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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs379157
log Bayes Factor = 53.3873
Chromosome 6   position 29,356,587  (GRCh37) Explore rs379157 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E10.9 Without complications
0.999 0.001 0.000
E00-E07 Disorders of thyroid gland
0.998 0.002 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.977 0.023 0.000
E10.1 With ketoacidosis
0.977 0.023 0.000
E10.3 With ophthalmic complications
0.974 0.026 0.000
E14 Unspecified diabetes mellitus
0.944 0.056 0.000
E13 Other specified diabetes mellitus
0.913 0.087 0.000
E10.2 With renal complications
0.897 0.103 0.000
E05.8 Other thyrotoxicosis
0.890 0.110 0.000
E10.4 With neurological complications
0.886 0.114 0.000
E13.9 Without complications
0.855 0.145 0.000
E14.3 With ophthalmic complications
0.817 0.183 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.812 0.188 0.000
E10.6 With other specified complications
0.809 0.191 0.000
E03 Other hypothyroidism
0.799 0.201 0.000
E14.4 With neurological complications
0.783 0.217 0.000
E14.8 With unspecified complications
0.783 0.217 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.241 0.759
E14.6 With other specified complications
0.734 0.266 0.000
E10.0 With coma
0.729 0.271 0.000
E10.7 With multiple complications
0.719 0.281 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.716 0.284 0.000
E00 Congenital iodine-deficiency syndrome
0.716 0.284 0.000
E14.2 Withrenal complications
0.709 0.290 0.000
E14.5 With peripheral circulatory complications
0.687 0.312 0.000
E14.1 With ketoacidosis
0.685 0.315 0.000
E14.7 With multiple complications
0.677 0.323 0.000
E14.0 With coma
0.677 0.323 0.000
E10.8 With unspecified complications
0.676 0.324 0.000
E03.8 Other specified hypothyroidism
0.666 0.334 0.000
E13.8 With unspecified complications
0.654 0.345 0.000
E13.7 With multiple complications
0.654 0.345 0.000
E13.6 With other specified complications
0.654 0.345 0.000
E13.5 With peripheral circulatory complications
0.654 0.345 0.000
E13.4 With neurological complications
0.654 0.345 0.000
E13.2 With renal complications
0.654 0.345 0.000
E13.1 With ketoacidosis
0.654 0.345 0.000
E13.0 With coma
0.654 0.345 0.000
E16.1 Other hypoglycaemia
0.647 0.352 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.647 0.353 0.000
E13.3 With ophthalmic complications
0.635 0.365 0.000
E10.5 With peripheral circulatory complications
0.627 0.373 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.610 0.390 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.600 0.400 0.000
E83 Disorders of mineral metabolism
0.000 0.404 0.595
E14.9 Without complications
0.580 0.420 0.000
E03.1 Congenital hypothyroidism without goitre
0.580 0.420 0.000
E40-E46 Malnutrition
0.580 0.420 0.000
E03.5 Myxoedema coma
0.573 0.427 0.000
E03.4 Atrophy of thyroid (acquired)
0.573 0.427 0.000
E03.3 Postinfectious hypothyroidism
0.573 0.427 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.436 0.564
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.513 0.487 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.513 0.487 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.513 0.487 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.513 0.487 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.513 0.487 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.513 0.487 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.513 0.487 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.513 0.487 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.479 0.520 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.540 0.460
E11 Non-insulin-dependent diabetes mellitus
0.449 0.551 0.000
E06 Thyroiditis
0.443 0.557 0.000
E07 Other disorders of thyroid
0.437 0.563 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.573 0.427
E83.8 Other disorders of mineral metabolism
0.000 0.573 0.427
E83.2 Disorders of zinc metabolism
0.000 0.573 0.427
E83.0 Disorders of copper metabolism
0.000 0.573 0.427
E50-E64 Other nutritional deficiencies
0.422 0.578 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.416 0.584 0.000
E45 Retarded development following protein-energy malnutrition
0.416 0.584 0.000
E43 Unspecified severe protein-energy malnutrition
0.416 0.584 0.000
E42 Marasmic kwashiorkor
0.416 0.584 0.000
E41 Nutritional marasmus
0.416 0.584 0.000
E40 Kwashiorkor
0.416 0.584 0.000
E11.6 With other specified complications
0.405 0.595 0.000
E11.1 With ketoacidosis
0.397 0.603 0.000
E11.0 With coma
0.388 0.612 0.000
E03.9 Hypothyroidism, unspecified
0.376 0.624 0.000
K90 Intestinal malabsorption
0.357 0.643 0.000
E11.5 With peripheral circulatory complications
0.336 0.664 0.000
E06.1 Subacute thyroiditis
0.332 0.668 0.000
E11.8 With unspecified complications
0.322 0.678 0.000
E11.7 With multiple complications
0.322 0.678 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.318 0.682 0.000
E06.4 Drug-induced thyroiditis
0.318 0.682 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.318 0.682 0.000
E06.0 Acute thyroiditis
0.318 0.682 0.000
E54 Ascorbic acid deficiency
0.317 0.683 0.000
E06.9 Thyroiditis, unspecified
0.316 0.684 0.000
E07.1 Dyshormogenetic goitre
0.313 0.686 0.000
E07.0 Hypersecretion of calcitonin
0.313 0.686 0.000
E56 Other vitamin deficiencies
0.313 0.686 0.000
E51 Thiamine deficiency
0.304 0.695 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.303 0.697 0.000
E63 Other nutritional deficiencies
0.303 0.697 0.000
E50 Vitamin A deficiency
0.303 0.697 0.000
E60 Dietary zinc deficiency
0.303 0.697 0.000
E59 Dietary selenium deficiency
0.303 0.697 0.000
E52 Niacin deficiency [pellagra]
0.303 0.697 0.000
E65-E68 Obesity and other hyperalimentation
0.302 0.698 0.000
E44.1 Mild protein-energy malnutrition
0.298 0.702 0.000
E44.0 Moderate protein-energy malnutrition
0.298 0.702 0.000
E06.5 Other chronic thyroiditis
0.281 0.718 0.000
E46 Unspecified protein-energy malnutrition
0.279 0.721 0.000
E55 Vitamin D deficiency
0.272 0.728 0.000
E58 Dietary calcium deficiency
0.269 0.731 0.000
E07.8 Other specified disorders of thyroid
0.263 0.737 0.000
K90.3 Pancreatic steatorrhoea
0.256 0.744 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.256 0.744 0.000
K90.1 Tropical sprue
0.256 0.744 0.000
E56.1 Deficiency of vitamin K
0.235 0.764 0.000
E53 Deficiency of other B group vitamins
0.229 0.771 0.000
E56.9 Vitamin deficiency, unspecified
0.225 0.775 0.000
E56.8 Deficiency of other vitamins
0.225 0.775 0.000
E56.0 Deficiency of vitamin E
0.225 0.775 0.000
E61 Deficiency of other nutrient elements
0.224 0.776 0.000
E51.2 Wernicke's encephalopathy
0.220 0.780 0.000
K90.8 Other intestinal malabsorption
0.219 0.781 0.000
E51.9 Thiamine deficiency, unspecified
0.218 0.781 0.000
E51.8 Other manifestations of thiamine deficiency
0.218 0.781 0.000
E51.1 Beriberi
0.218 0.781 0.000
E50.9 Vitamin A deficiency, unspecified
0.217 0.782 0.000
E50.8 Other manifestations of vitamin A deficiency
0.217 0.782 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.217 0.782 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.217 0.782 0.000
E50.5 Vitamin A deficiency with night blindness
0.217 0.782 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.217 0.782 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.217 0.782 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.217 0.782 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.217 0.782 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.217 0.782 0.000
E63.9 Nutritional deficiency, unspecified
0.217 0.782 0.000
E63.8 Other specified nutritional deficiencies
0.217 0.782 0.000
E63.1 Imbalance of constituents of food intake
0.217 0.782 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.217 0.782 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.217 0.782 0.000
E64.8 Sequelae of other nutritional deficiencies
0.217 0.782 0.000
E64.3 Sequelae of rickets
0.217 0.782 0.000
E64.2 Sequelae of vitamin C deficiency
0.217 0.782 0.000
E64.1 Sequelae of vitamin A deficiency
0.217 0.782 0.000
E64.0 Sequelae of protein-energy malnutrition
0.217 0.782 0.000
E67 Other hyperalimentation
0.216 0.783 0.000
E68 Sequelae of hyperalimentation
0.216 0.783 0.000
L40 Psoriasis
0.200 0.800 0.000
L40.9 Psoriasis, unspecified
0.196 0.804 0.000
E55.0 Rickets, active
0.195 0.805 0.000
L40.5 Arthropathic psoriasis
0.192 0.808 0.000
L40.0 Psoriasis vulgaris
0.185 0.815 0.000
E11.3 With ophthalmic complications
0.181 0.819 0.000
L40.4 Guttate psoriasis
0.181 0.819 0.000
E53.9 Vitamin B deficiency, unspecified
0.169 0.831 0.000
E53.1 Pyridoxine deficiency
0.164 0.835 0.000
E53.0 Riboflavin deficiency
0.164 0.835 0.000
E55.9 Vitamin D deficiency, unspecified
0.164 0.836 0.000
E61.9 Deficiency of nutrient element, unspecified
0.161 0.839 0.000
E61.8 Deficiency of other specified nutrient elements
0.161 0.839 0.000
E61.7 Deficiency of multiple nutrient elements
0.161 0.839 0.000
E61.6 Vanadium deficiency
0.161 0.839 0.000
E61.5 Molybdenum deficiency
0.161 0.839 0.000
E61.4 Chromium deficiency
0.161 0.839 0.000
E61.3 Manganese deficiency
0.161 0.839 0.000
E61.0 Copper deficiency
0.161 0.839 0.000
L40.1 Generalised pustular psoriasis
0.161 0.839 0.000
E67.8 Other specified hyperalimentation
0.155 0.844 0.000
E67.3 Hypervitaminosis D
0.155 0.844 0.000
E67.2 Megavitamin-B6 syndrome
0.155 0.844 0.000
E67.1 Hypercarotenaemia
0.155 0.844 0.000
E67.0 Hypervitaminosis A
0.155 0.844 0.000
E65 Localised adiposity
0.153 0.847 0.000
E07.9 Disorder of thyroid, unspecified
0.151 0.849 0.000
I83 Varicose veins of lower extremities
0.000 0.849 0.151
L40.3 Pustulosis palmaris et plantaris
0.150 0.849 0.000
L40.2 Acrodermatitis continua
0.144 0.856 0.000
E61.1 Iron deficiency
0.135 0.865 0.000
L40-L45 Papulosquamous disorders
0.133 0.867 0.000
E11.2 With renal complications
0.123 0.877 0.000
E61.2 Magnesium deficiency
0.123 0.877 0.000
L43 Lichen planus
0.119 0.881 0.000
L43.9 Lichen planus, unspecified
0.109 0.891 0.000
L40.8 Other psoriasis
0.104 0.896 0.000
L44 Other papulosquamous disorders
0.104 0.896 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.897 0.103
E06.3 Autoimmune thyroiditis
0.099 0.901 0.001
E11.4 With neurological complications
0.099 0.901 0.000
K90.9 Intestinal malabsorption, unspecified
0.098 0.901 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.902 0.098
L41 Parapsoriasis
0.096 0.904 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.096 0.904 0.000
L42 Pityriasis rosea
0.086 0.913 0.000
L43.3 Subacute (active) lichen planus
0.086 0.914 0.000
L43.2 Lichenoid drug reaction
0.086 0.914 0.000
L43.1 Bullous lichen planus
0.086 0.914 0.000
L43.0 Hypertrophic lichen planus
0.086 0.914 0.000
L43.8 Other lichen planus
0.085 0.915 0.000
L44.0 Pityriasis rubra pilaris
0.084 0.916 0.000
E53.8 Deficiency of other specified B group vitamins
0.080 0.920 0.000
L44.9 Papulosquamous disorder, unspecified
0.075 0.925 0.000
L44.8 Other specified papulosquamous disorders
0.075 0.925 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.075 0.925 0.000
L44.3 Lichen ruber moniliformis
0.075 0.925 0.000
L44.2 Lichen striatus
0.075 0.925 0.000
L44.1 Lichen nitidus
0.075 0.925 0.000
R31 Unspecified haematuria
0.000 0.930 0.070
L41.1 Pityriasis lichenoides chronica
0.069 0.930 0.000
L41.9 Parapsoriasis, unspecified
0.069 0.931 0.000
L41.8 Other parapsoriasis
0.069 0.931 0.000
L41.5 Retiform parapsoriasis
0.069 0.931 0.000
L41.4 Large plaque parapsoriasis
0.069 0.931 0.000
L41.3 Small plaque parapsoriasis
0.069 0.931 0.000
L41.2 Lymphomatoid papulosis
0.069 0.931 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.069 0.931 0.000
E04 Other non-toxic goitre
0.064 0.934 0.002
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.938 0.062
E20-E35 Disorders of other endocrine glands
0.061 0.939 0.000
H40.2 Primary angle-closure glaucoma
0.000 0.943 0.057
E83.5 Disorders of calcium metabolism
0.000 0.951 0.049
E04.8 Other specified non-toxic goitre
0.046 0.952 0.002
E24 Cushing's syndrome
0.046 0.954 0.000
E20 Hypoparathyroidism
0.045 0.955 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.044 0.956 0.000
E32 Diseases of thymus
0.044 0.956 0.000
E30 Disorders of puberty, not elsewhere classified
0.044 0.956 0.000
E25 Adrenogenital disorders
0.043 0.957 0.000
E29 Testicular dysfunction
0.042 0.958 0.000
E31 Polyglandular dysfunction
0.041 0.958 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.041 0.959 0.000
E24.2 Drug-induced Cushing's syndrome
0.038 0.962 0.000
E34 Other endocrine disorders
0.038 0.962 0.000
E04.0 Non-toxic diffuse goitre
0.033 0.965 0.002
E24.8 Other Cushing's syndrome
0.035 0.965 0.000
H40.5 Glaucoma secondary to other eye disorders
0.000 0.965 0.035
E21.4 Other specified disorders of parathyroid gland
0.034 0.966 0.000
E20.9 Hypoparathyroidism, unspecified
0.034 0.966 0.000
E21.3 Hyperparathyroidism, unspecified
0.034 0.966 0.000
E24.0 Pituitary-dependent Cushing's disease
0.034 0.966 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.033 0.967 0.000
E24.3 Ectopic ACTH syndrome
0.033 0.967 0.000
E24.1 Nelson's syndrome
0.033 0.967 0.000
H40 Glaucoma
0.000 0.967 0.033
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.033 0.967 0.000
E20.8 Other hypoparathyroidism
0.032 0.967 0.000
E20.1 Pseudohypoparathyroidism
0.032 0.967 0.000
E20.0 Idiopathic hypoparathyroidism
0.032 0.967 0.000
E30.9 Disorder of puberty, unspecified
0.031 0.968 0.000
E30.8 Other disorders of puberty
0.031 0.968 0.000
E30.1 Precocious puberty
0.031 0.968 0.000
E30.0 Delayed puberty
0.031 0.968 0.000
E32.9 Disease of thymus, unspecified
0.031 0.968 0.000
E32.8 Other diseases of thymus
0.031 0.968 0.000
E32.1 Abscess of thymus
0.031 0.968 0.000
E32.0 Persistent hyperplasia of thymus
0.031 0.968 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.031 0.968 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.031 0.968 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.031 0.968 0.000
E21.2 Other hyperparathyroidism
0.031 0.969 0.000
E25.9 Adrenogenital disorder, unspecified
0.031 0.969 0.000
E25.8 Other adrenogenital disorders
0.031 0.969 0.000
E26 Hyperaldosteronism
0.031 0.969 0.000
E29.9 Testicular dysfunction, unspecified
0.030 0.969 0.000
E29.8 Other testicular dysfunction
0.030 0.970 0.000
E29.0 Testicular hyperfunction
0.030 0.970 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.030 0.970 0.000
E31.9 Polyglandular dysfunction, unspecified
0.030 0.970 0.000
E31.8 Other polyglandular dysfunction
0.030 0.970 0.000
E31.1 Polyglandular hyperfunction
0.030 0.970 0.000
E23 Hypofunction and other disorders of pituitary gland
0.030 0.970 0.000
E34.3 Short stature, not elsewhere classified
0.029 0.970 0.000
E34.9 Endocrine disorder, unspecified
0.029 0.971 0.000
E28 Ovarian dysfunction
0.028 0.972 0.000
E29.1 Testicular hypofunction
0.028 0.972 0.000
E04.9 Non-toxic goitre, unspecified
0.027 0.972 0.001
E31.0 Autoimmune polyglandular failure
0.027 0.972 0.000
E34.5 Androgen resistance syndrome
0.027 0.973 0.000
E34.4 Constitutional tall stature
0.027 0.973 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.027 0.973 0.000
E34.1 Other hypersecretion of intestinal hormones
0.027 0.973 0.000
E22 Hyperfunction of pituitary gland
0.027 0.973 0.000
H40.3 Glaucoma secondary to eye trauma
0.000 0.974 0.026
E27 Other disorders of adrenal gland
0.025 0.975 0.000
H40.8 Other glaucoma
0.000 0.975 0.025
E24.9 Cushing's syndrome, unspecified
0.025 0.975 0.000
H40.6 Glaucoma secondary to drugs
0.000 0.976 0.024
E23.7 Disorder of pituitary gland, unspecified
0.024 0.976 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.023 0.977 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.023 0.977 0.000
E34.8 Other specified endocrine disorders
0.022 0.978 0.000
E26.8 Other hyperaldosteronism
0.022 0.978 0.000
E26.1 Secondary hyperaldosteronism
0.022 0.978 0.000
E23.2 Diabetes insipidus
0.022 0.978 0.000
M07.3 Other psoriatic arthropathies
0.022 0.978 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.022 0.978 0.000
E23.1 Drug-induced hypopituitarism
0.022 0.978 0.000
H40.4 Glaucoma secondary to eye inflammation
0.000 0.978 0.022
E34.0 Carcinoid syndrome
0.021 0.979 0.000
E28.9 Ovarian dysfunction, unspecified
0.020 0.979 0.000
E28.8 Other ovarian dysfunction
0.020 0.979 0.000
E28.1 Androgen excess
0.020 0.979 0.000
E28.0 Oestrogen excess
0.020 0.979 0.000
K90-K93 Other diseases of the digestive system
0.020 0.980 0.000
E22.1 Hyperprolactinaemia
0.020 0.980 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.019 0.980 0.000
E22.8 Other hyperfunction of pituitary gland
0.019 0.980 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.020 0.980 0.000
E27.1 Primary adrenocortical insufficiency
0.019 0.981 0.000
M07.38 Other psoriatic arthropathies (Other)
0.019 0.981 0.000
E27.9 Disorder of adrenal gland, unspecified
0.019 0.981 0.000
E26.9 Hyperaldosteronism, unspecified
0.019 0.981 0.000
E28.3 Primary ovarian failure
0.019 0.981 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.019 0.981 0.000
E27.5 Adrenomedullary hyperfunction
0.018 0.981 0.000
E27.0 Other adrenocortical overactivity
0.018 0.981 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.018 0.982 0.000
E23.6 Other disorders of pituitary gland
0.017 0.983 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.017 0.983 0.000
H40.0 Glaucoma suspect
0.000 0.983 0.017
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.016 0.984 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.016 0.984 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.016 0.984 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.016 0.984 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.016 0.984 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.016 0.984 0.000
E66 Obesity
0.015 0.984 0.000
E26.0 Primary hyperaldosteronism
0.015 0.984 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.015 0.985 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.015 0.985 0.000
E27.2 Addisonian crisis
0.014 0.985 0.000
H40-H42 Glaucoma
0.000 0.986 0.014
E11.9 Without complications
0.013 0.987 0.000
E66.1 Drug-induced obesity
0.011 0.989 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.011 0.989 0.000
K93.1 Megacolon in Chagas' disease
0.011 0.989 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.011 0.989 0.000
E27.8 Other specified disorders of adrenal gland
0.010 0.990 0.000
H42 Glaucoma in diseases classified elsewhere
0.000 0.990 0.010
E23.0 Hypopituitarism
0.010 0.990 0.000
E70-E90 Metabolic disorders
0.003 0.990 0.007
E28.2 Polycystic ovarian syndrome
0.009 0.991 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.009 0.991 0.000
M07 Psoriatic and enteropathic arthropathies
0.009 0.991 0.000
E22.0 Acromegaly and pituitary gigantism
0.008 0.991 0.001
E04.1 Non-toxic single thyroid nodule
0.007 0.991 0.002
E21.0 Primary hyperparathyroidism
0.009 0.991 0.000
H40.1 Primary open-angle glaucoma
0.000 0.991 0.009
E66.2 Extreme obesity with alveolar hypoventilation
0.008 0.992 0.000
H42.8 Glaucoma in other diseases classified elsewhere
0.000 0.992 0.007
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases
0.000 0.992 0.007
E70 Disorders of aromatic amino-acid metabolism
0.002 0.993 0.005
E84 Cystic fibrosis
0.002 0.993 0.005
E77 Disorders of glycoprotein metabolism
0.002 0.993 0.005
E76 Disorders of glycosaminoglycan metabolism
0.002 0.993 0.005
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.002 0.993 0.005
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.002 0.993 0.005
E79 Disorders of purine and pyrimidine metabolism
0.002 0.993 0.005
E72 Other disorders of amino-acid metabolism
0.002 0.993 0.005
M07.5 Arthropathy in ulcerative colitis
0.007 0.993 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.007 0.993 0.000
M07.2 Psoriatic spondylitis
0.007 0.993 0.000
M07.1 Arthritis mutilans
0.007 0.993 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.007 0.993 0.000
E73 Lactose intolerance
0.002 0.993 0.005
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.002 0.993 0.004
M07.6 Other enteropathic arthropathies
0.007 0.993 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.006 0.994 0.000
E74 Other disorders of carbohydrate metabolism
0.002 0.994 0.004
E85 Amyloidosis
0.002 0.994 0.005
E66.0 Obesity due to excess calories
0.005 0.994 0.001
E80 Disorders of porphyrin and bilirubin metabolism
0.001 0.994 0.005
O20.0 Threatened abortion
0.006 0.994 0.000
E04.2 Non-toxic multinodular goitre
0.002 0.994 0.004
C20 Malignant neoplasm of rectum
0.006 0.994 0.000
E70.3 Albinism
0.001 0.994 0.004
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.002 0.994 0.004
E70.8 Other disorders of aromatic amino-acid metabolism
0.002 0.994 0.004
E70.2 Disorders of tyrosine metabolism
0.002 0.994 0.004
E70.1 Other hyperphenylalaninaemias
0.002 0.994 0.004
E70.0 Classical phenylketonuria
0.002 0.994 0.004
E84.9 Cystic fibrosis, unspecified
0.001 0.994 0.004
H40.9 Glaucoma, unspecified
0.000 0.994 0.006
E84.8 Cystic fibrosis with other manifestations
0.002 0.994 0.004
E84.1 Cystic fibrosis with intestinal manifestations
0.002 0.994 0.004
E84.0 Cystic fibrosis with pulmonary manifestations
0.002 0.994 0.004
E71.3 Disorders of fatty-acid metabolism
0.002 0.994 0.004
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.002 0.994 0.004
E71.1 Other disorders of branched-chain amino-acid metabolism
0.002 0.994 0.004
E71.0 Maple-syrup-urine disease
0.002 0.994 0.004
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.002 0.994 0.004
E76.8 Other disorders of glucosaminoglycan metabolism
0.002 0.994 0.004
E76.3 Mucopolysaccharidosis, unspecified
0.002 0.994 0.004
E76.2 Other mucopolysaccharidoses
0.002 0.994 0.004
E76.1 Mucopolysaccharidosis, type II
0.002 0.994 0.004
E76.0 Mucopolysaccharidosis, type I
0.002 0.994 0.004
E77.9 Disorder of glycoprotein metabolism, unspecified
0.002 0.994 0.004
E77.8 Other disorders of glycoprotein metabolism
0.002 0.994 0.004
E77.1 Defects in glycoprotein degradation
0.002 0.994 0.004
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.002 0.994 0.004
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.002 0.994 0.004
E79.8 Other disorders of purine and pyrimidine metabolism
0.002 0.994 0.004
E79.1 Lesch-Nyhan syndrome
0.002 0.994 0.004
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.995 0.004
E72.9 Disorder of amino-acid metabolism, unspecified
0.002 0.995 0.004
E72.8 Other specified disorders of amino-acid metabolism
0.002 0.995 0.004
E72.5 Disorders of glycine metabolism
0.002 0.995 0.004
E72.4 Disorders of ornithine metabolism
0.002 0.995 0.004
E72.3 Disorders of lysine and hydroxylysine metabolism
0.002 0.995 0.004
E72.2 Disorders of urea cycle metabolism
0.002 0.995 0.004
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.002 0.995 0.004
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.005 0.995 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.005 0.995 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.005 0.995 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.005 0.995 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.005 0.995 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.005 0.995 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.005 0.995 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.005 0.995 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.005 0.995 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.005 0.995 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.005 0.995 0.000
M07.18 Arthritis mutilans (Other)
0.005 0.995 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.005 0.995 0.000
M07.16 Arthritis mutilans (Lower leg)
0.005 0.995 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.005 0.995 0.000
M07.14 Arthritis mutilans (Hand)
0.005 0.995 0.000
M07.13 Arthritis mutilans (Forearm)
0.005 0.995 0.000
M07.12 Arthritis mutilans (Upper arm)
0.005 0.995 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.005 0.995 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.005 0.995 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.005 0.995 0.000
M07.28 Psoriatic spondylitis (Other)
0.005 0.995 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.005 0.995 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.005 0.995 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.005 0.995 0.000
M07.24 Psoriatic spondylitis (Hand)
0.005 0.995 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.005 0.995 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.005 0.995 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.005 0.995 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.005 0.995 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.005 0.995 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.005 0.995 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.005 0.995 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.005 0.995 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.005 0.995 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.005 0.995 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.005 0.995 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.005 0.995 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.005 0.995 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.005 0.995 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.005 0.995 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.005 0.995 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.005 0.995 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.005 0.995 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.005 0.995 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.005 0.995 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.005 0.995 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.005 0.995 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.005 0.995 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.005 0.995 0.000
H66.3 Other chronic suppurative otitis media
0.000 0.995 0.005
E72.0 Disorders of amino-acid transport
0.002 0.995 0.004
E73.8 Other lactose intolerance
0.001 0.995 0.004
E73.1 Secondary lactase deficiency
0.001 0.995 0.004
E73.0 Congenital lactase deficiency
0.001 0.995 0.004
E75.6 Lipid storage disorder, unspecified
0.002 0.995 0.003
E75.4 Neuronal ceroid lipofuscinosis
0.002 0.995 0.003
E75.3 Sphingolipidosis, unspecified
0.002 0.995 0.003
E75.1 Other gangliosidosis
0.002 0.995 0.003
E75.0 GM2 gangliosidosis
0.002 0.995 0.003
M07.68 Other enteropathic arthropathies (Other)
0.005 0.995 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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