TreeWAS – Variant ID: rs3796392

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	0.023	0.977
I30-I52 Other forms of heart disease	0.022	0.978
I20-I25 Ischaemic heart diseases	0.021	0.979
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.020	0.980
# Top node	0.020	0.980
I25 Chronic ischaemic heart disease	0.020	0.980
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.019	0.981
I47 Paroxysmal tachycardia	0.019	0.981
I50 Heart failure	0.018	0.982
I20 Angina pectoris	0.018	0.982
I51 Complications and ill-defined descriptions of heart disease	0.018	0.982
S00-S09 Injuries to the head	0.018	0.982
I10-I15 Hypertensive diseases	0.018	0.982
I70-I79 Diseases of arteries, arterioles and capillaries	0.018	0.982
I34 Nonrheumatic mitral valve disorders	0.018	0.982
Chapter V Mental and behavioural disorders	0.017	0.983
I25.8 Other forms of chronic ischaemic heart disease	0.017	0.983
I60-I69 Cerebrovascular diseases	0.017	0.983
I45 Other conduction disorders	0.017	0.983
I35 Nonrheumatic aortic valve disorders	0.017	0.983
M20-M25 Other joint disorders	0.017	0.983
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.017	0.983
I25.2 Old myocardial infarction	0.017	0.983
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.017	0.983
M70-M79 Other soft tissue disorders	0.017	0.983
I47.2 Ventricular tachycardia	0.017	0.983
M15-M19 Arthrosis	0.017	0.983
I44 Atrioventricular and left bundle-branch block	0.017	0.983
I05-I09 Chronic rheumatic heart diseases	0.016	0.983
I00-I02 Acute rheumatic fever	0.016	0.983
Chapter XV Pregnancy, childbirth and the puerperium	0.016	0.983
M50-M54 Other dorsopathies	0.016	0.984
I52 Other heart disorders in diseases classified elsewhere	0.016	0.984
I49 Other cardiac arrhythmias	0.016	0.984
I48 Atrial fibrillation and flutter	0.016	0.984
I46 Cardiac arrest	0.016	0.984
I43 Cardiomyopathy in diseases classified elsewhere	0.016	0.984
I42 Cardiomyopathy	0.016	0.984
I41 Myocarditis in diseases classified elsewhere	0.016	0.984
I40 Acute myocarditis	0.016	0.984
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.016	0.984
I37 Pulmonary valve disorders	0.016	0.984
I36 Nonrheumatic tricuspid valve disorders	0.016	0.984
I33 Acute and subacute endocarditis	0.016	0.984
I32 Pericarditis in diseases classified elsewhere	0.016	0.984
I31 Other diseases of pericardium	0.016	0.984
I30 Acute pericarditis	0.016	0.984
I38 Endocarditis, valve unspecified	0.016	0.984
Chapter VII Diseases of the eye and adnexa	0.016	0.984
M05-M14 Inflammatory polyarthropathies	0.016	0.984
I25.1 Atherosclerotic heart disease	0.016	0.984
Chapter XIV Diseases of the genitourinary system	0.016	0.984
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.016	0.984
Chapter VI Diseases of the nervous system	0.016	0.984
I95-I99 Other and unspecified disorders of the circulatory system	0.016	0.984
F40-F48 Neurotic, stress-related and somatoform disorders	0.016	0.984
M65-M68 Disorders of synovium and tendon	0.016	0.984
M40-M43 Deforming dorsopathies	0.015	0.984
I24 Other acute ischaemic heart diseases	0.015	0.984
I23 Certain current complications following acute myocardial infarction	0.015	0.984
I22 Subsequent myocardial infarction	0.015	0.984
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.015	0.985
I50.1 Left ventricular failure	0.015	0.985
S01 Open wound of head	0.015	0.985
M75 Shoulder lesions	0.015	0.985
M45-M49 Spondylopathies	0.015	0.985
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.015	0.985
M91-M94 Chondropathies	0.015	0.985
M86-M90 Other osteopathies	0.015	0.985
M60-M63 Disorders of muscles	0.015	0.985
M00-M03 Infectious arthropathies	0.015	0.985
S09 Other and unspecified injuries of head	0.015	0.985
Chapter XXII Codes for special purposes	0.015	0.985
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.015	0.985
Chapter XVI Certain conditions originating in the perinatal period	0.015	0.985
I34.1 Mitral (valve) prolapse	0.015	0.985
I20.9 Angina pectoris, unspecified	0.015	0.985
F41 Other anxiety disorders	0.014	0.985
I25.6 Silent myocardial ischaemia	0.014	0.986
I25.5 Ischaemic cardiomyopathy	0.014	0.986
I25.4 Coronary artery aneurysm	0.014	0.986
I25.3 Aneurysm of heart	0.014	0.986
I25.0 Atherosclerotic cardiovascular disease, so described	0.014	0.986
S00 Superficial injury of head	0.014	0.986
Chapter I Certain infectious and parasitic diseases	0.014	0.986
Chapter XX External causes of morbidity and mortality	0.014	0.986
M25 Other joint disorders, not elsewhere classified	0.014	0.986
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.014	0.986
M80-M85 Disorders of bone density and structure	0.014	0.986
Chapter XII Diseases of the skin and subcutaneous tissue	0.014	0.986
I73 Other peripheral vascular diseases	0.014	0.986
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.014	0.986
T79-T79 Certain early complications of trauma	0.014	0.986
T66-T78 Other and unspecified effects of external causes	0.014	0.986
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.014	0.986
T36-T50 Poisoning by drugs, medicaments and biological substances	0.014	0.986
T33-T35 Frostbite	0.014	0.986
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.014	0.986
T26-T28 Burns and corrosions confined to eye and internal organs	0.014	0.986
T20-T25 Burns and corrosions of external body surface, specified by site	0.014	0.986
T15-T19 Effects of foreign body entering through natural orifice	0.014	0.986
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.014	0.986
T00-T07 Injuries involving multiple body regions	0.014	0.986
S90-S99 Injuries to the ankle and foot	0.014	0.986
S70-S79 Injuries to the hip and thigh	0.014	0.986
S40-S49 Injuries to the shoulder and upper arm	0.014	0.986
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.014	0.986
S20-S29 Injuries to the thorax	0.014	0.986
S10-S19 Injuries to the neck	0.014	0.986
I51.8 Other ill-defined heart diseases	0.014	0.986
S80-S89 Injuries to the knee and lower leg	0.014	0.986
I21 Acute myocardial infarction	0.014	0.986
I20.0 Unstable angina	0.014	0.986
I10 Essential (primary) hypertension	0.014	0.986
F41.9 Anxiety disorder, unspecified	0.014	0.986
I47.9 Paroxysmal tachycardia, unspecified	0.014	0.986
I47.0 Reentry ventricular arrhythmia	0.014	0.986
S60-S69 Injuries to the wrist and hand	0.014	0.986
Chapter II Neoplasms	0.014	0.986
I67 Other cerebrovascular diseases	0.014	0.986
Chapter VIII Diseases of the ear and mastoid process	0.014	0.986
N80-N98 Noninflammatory disorders of female genital tract	0.014	0.986
I50.0 Congestive heart failure	0.013	0.986
I45.1 Other and unspecified right bundle-branch block	0.013	0.986
I51.7 Cardiomegaly	0.013	0.986
I35.0 Aortic (valve) stenosis	0.013	0.986
M23 Internal derangement of knee	0.013	0.987
S50-S59 Injuries to the elbow and forearm	0.013	0.987
I47.1 Supraventricular tachycardia	0.013	0.987
I50.9 Heart failure, unspecified	0.013	0.987
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.013	0.987
M17 Gonarthrosis [arthrosis of knee]	0.013	0.987
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.013	0.987
M16 Coxarthrosis [arthrosis of hip]	0.013	0.987
I12 Hypertensive renal disease	0.013	0.987
M75.0 Adhesive capsulitis of shoulder	0.013	0.987
Chapter IV Endocrine, nutritional and metabolic diseases	0.013	0.987
N92 Excessive, frequent and irregular menstruation	0.013	0.987
T84.0 Mechanical complication of internal joint prosthesis	0.013	0.987
O60-O75 Complications of labour and delivery	0.013	0.987
I20.8 Other forms of angina pectoris	0.013	0.987
I20.1 Angina pectoris with documented spasm	0.013	0.987
I51.9 Heart disease, unspecified	0.013	0.987
I51.6 Cardiovascular disease, unspecified	0.013	0.987
I51.5 Myocardial degeneration	0.013	0.987
I51.4 Myocarditis, unspecified	0.013	0.987
I51.3 Intracardiac thrombosis, not elsewhere classified	0.013	0.987
I51.2 Rupture of papillary muscle, not elsewhere classified	0.013	0.987
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.013	0.987
I51.0 Cardiac septal defect, acquired	0.013	0.987
S08 Traumatic amputation of part of head	0.013	0.987
S07 Crushing injury of head	0.013	0.987
S06 Intracranial injury	0.013	0.987
S05 Injury of eye and orbit	0.013	0.987
S04 Injury of cranial nerves	0.013	0.987
S03 Dislocation, sprain and strain of joints and ligaments of head	0.013	0.987
S02 Fracture of skull and facial bones	0.013	0.987
I83 Varicose veins of lower extremities	0.013	0.987
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.013	0.987
I15 Secondary hypertension	0.013	0.987
I13 Hypertensive heart and renal disease	0.013	0.987
I11 Hypertensive heart disease	0.013	0.987
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.013	0.987
I78 Diseases of capillaries	0.013	0.987
I77 Other disorders of arteries and arterioles	0.013	0.987
I74 Arterial embolism and thrombosis	0.013	0.987
I72 Other aneurysm	0.013	0.987
I71 Aortic aneurysm and dissection	0.013	0.987
I70 Atherosclerosis	0.013	0.987
N00-N08 Glomerular diseases	0.013	0.987
M54 Dorsalgia	0.013	0.987
M51 Other intervertebral disk disorders	0.013	0.987
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.013	0.987
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.013	0.987
I34.8 Other nonrheumatic mitral valve disorders	0.013	0.987
I34.2 Nonrheumatic mitral (valve) stenosis	0.013	0.987
I26 Pulmonary embolism	0.013	0.987
H02 Other disorders of eyelid	0.013	0.987
M13 Other arthritis	0.013	0.987
F99-F99 Unspecified mental disorder	0.013	0.987
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.013	0.987
F80-F89 Disorders of psychological development	0.013	0.987
F70-F79 Mental retardation	0.013	0.987
F60-F69 Disorders of adult personality and behaviour	0.013	0.987
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.013	0.987
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.013	0.987
F00-F09 Organic, including symptomatic, mental disorders	0.013	0.987
M20 Acquired deformities of fingers and toes	0.013	0.987
I69 Sequelae of cerebrovascular disease	0.013	0.987
I68 Cerebrovascular disorders in diseases classified elsewhere	0.013	0.987
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.013	0.987
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.013	0.987
I62 Other nontraumatic intracranial haemorrhage	0.013	0.987
I61 Intracerebral haemorrhage	0.013	0.987
I60 Subarachnoid haemorrhage	0.013	0.987
I64 Stroke, not specified as haemorrhage or infarction	0.013	0.987
N92.0 Excessive and frequent menstruation with regular cycle	0.013	0.987
I63 Cerebral infarction	0.012	0.987
S09.9 Unspecified injury of head	0.012	0.987
I35.9 Aortic valve disorder, unspecified	0.012	0.987
I35.8 Other aortic valve disorders	0.012	0.987
I35.2 Aortic (valve) stenosis with insufficiency	0.012	0.987
I35.1 Aortic (valve) insufficiency	0.012	0.987
I45.9 Conduction disorder, unspecified	0.012	0.987
I45.8 Other specified conduction disorders	0.012	0.987
I45.6 Preexcitation syndrome	0.012	0.987
I45.5 Other specified heart block	0.012	0.987
I45.4 Nonspecific intraventricular block	0.012	0.987
I45.3 Trifascicular block	0.012	0.987
I45.2 Bifascicular block	0.012	0.987
I45.0 Right fascicular block	0.012	0.987
O80-O84 Delivery	0.012	0.987
I44.7 Left bundle-branch block, unspecified	0.012	0.987
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.012	0.987
M35 Other systemic involvement of connective tissue	0.012	0.987
M34 Systemic sclerosis	0.012	0.987
M33 Dermatopolymyositis	0.012	0.987
M32 Systemic lupus erythematosus	0.012	0.987
M31 Other necrotising vasculopathies	0.012	0.987
M30 Polyarteritis nodosa and related conditions	0.012	0.987
M24 Other specific joint derangements	0.012	0.987
M22 Disorders of patella	0.012	0.987
M21 Other acquired deformities of limbs	0.012	0.987
T88 Other complications of surgical and medical care, not elsewhere classified	0.012	0.987
T87 Complications peculiar to reattachment and amputation	0.012	0.987
T86 Failure and rejection of transplanted organs and tissues	0.012	0.987
T85 Complications of other internal prosthetic devices, implants and grafts	0.012	0.987
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.012	0.987
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.012	0.987
T80 Complications following infusion, transfusion and therapeutic injection	0.012	0.987
I34.0 Mitral (valve) insufficiency	0.012	0.987
I25.9 Chronic ischaemic heart disease, unspecified	0.012	0.987
T81 Complications of procedures, not elsewhere classified	0.012	0.987
I28 Other diseases of pulmonary vessels	0.012	0.988
I27 Other pulmonary heart diseases	0.012	0.988
M75.4 Impingement syndrome of shoulder	0.012	0.988
M19 Other arthrosis	0.012	0.988
M65 Synovitis and tenosynovitis	0.012	0.988
M25.5 Pain in joint	0.012	0.988
M10 Gout	0.012	0.988
N10-N16 Renal tubulo-interstitial diseases	0.012	0.988
M77 Other enthesopathies	0.012	0.988
M76 Enthesopathies of lower limb, excluding foot	0.012	0.988
M73 Soft tissue disorders in diseases classified elsewhere	0.012	0.988
M71 Other bursopathies	0.012	0.988
M70 Soft tissue disorders related to use, overuse and pressure	0.012	0.988
M18 Arthrosis of first carpometacarpal joint	0.012	0.988
M15 Polyarthrosis	0.012	0.988
M43 Other deforming dorsopathies	0.012	0.988
N25-N29 Other disorders of kidney and ureter	0.012	0.988
I44.6 Other and unspecified fascicular block	0.012	0.988
I44.5 Left posterior fascicular block	0.012	0.988
I44.4 Left anterior fascicular block	0.012	0.988
I44.3 Other and unspecified atrioventricular block	0.012	0.988
I44.2 Atrioventricular block, complete	0.012	0.988
I44.1 Atrioventricular block, second degree	0.012	0.988
I44.0 Atrioventricular block, first degree	0.012	0.988
F30-F39 Mood [affective] disorders	0.012	0.988
G20-G26 Extrapyramidal and movement disorders	0.012	0.988
O94-O99 Other obstetric conditions, not elsewhere classified	0.012	0.988
O85-O92 Complications predominantly related to the puerperium	0.012	0.988
O20-O29 Other maternal disorders predominantly related to pregnancy	0.012	0.988
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.012	0.988
O00-O08 Pregnancy with abortive outcome	0.012	0.988
I02 Rheumatic chorea	0.012	0.988
I01 Rheumatic fever with heart involvement	0.012	0.988
I00 Rheumatic fever without mention of heart involvement	0.012	0.988
I09 Other rheumatic heart diseases	0.012	0.988
I08 Multiple valve diseases	0.012	0.988
I07 Rheumatic tricuspid valve diseases	0.012	0.988
I06 Rheumatic aortic valve diseases	0.012	0.988
I05 Rheumatic mitral valve diseases	0.012	0.988
G40-G47 Episodic and paroxysmal disorders	0.012	0.988
S01.8 Open wound of other parts of head	0.012	0.988
M72 Fibroblastic disorders	0.012	0.988
M53 Other dorsopathies, not elsewhere classified	0.012	0.988
M50 Cervical disk disorders	0.012	0.988
S01.0 Open wound of scalp	0.012	0.988
S00.8 Superficial injury of other parts of head	0.012	0.988
M16.1 Other primary coxarthrosis	0.012	0.988
N20-N23 Urolithiasis	0.012	0.988
I30.9 Acute pericarditis, unspecified	0.012	0.988
I30.8 Other forms of acute pericarditis	0.012	0.988
I30.1 Infective pericarditis	0.012	0.988
I30.0 Acute nonspecific idiopathic pericarditis	0.012	0.988
I31.9 Disease of pericardium, unspecified	0.012	0.988
I31.8 Other specified diseases of pericardium	0.012	0.988
I31.3 Pericardial effusion (noninflammatory)	0.012	0.988
I31.2 Haemopericardium, not elsewhere classified	0.012	0.988
I31.1 Chronic constrictive pericarditis	0.012	0.988
I31.0 Chronic adhesive pericarditis	0.012	0.988
I32.8 Pericarditis in other diseases classified elsewhere	0.012	0.988
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.012	0.988
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.012	0.988
I33.9 Acute endocarditis, unspecified	0.012	0.988
I33.0 Acute and subacute infective endocarditis	0.012	0.988
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.012	0.988
I36.8 Other nonrheumatic tricuspid valve disorders	0.012	0.988
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.012	0.988
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.012	0.988
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.012	0.988
I37.9 Pulmonary valve disorder, unspecified	0.012	0.988
I37.8 Other pulmonary valve disorders	0.012	0.988
I37.2 Pulmonary valve stenosis with insufficiency	0.012	0.988
I37.1 Pulmonary valve insufficiency	0.012	0.988
I37.0 Pulmonary valve stenosis	0.012	0.988
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.012	0.988
I39.4 Multiple valve disorders in diseases classified elsewhere	0.012	0.988
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.012	0.988
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.012	0.988
I39.1 Aortic valve disorders in diseases classified elsewhere	0.012	0.988
I39.0 Mitral valve disorders in diseases classified elsewhere	0.012	0.988
I40.9 Acute myocarditis, unspecified	0.012	0.988
I40.8 Other acute myocarditis	0.012	0.988
I40.1 Isolated myocarditis	0.012	0.988
I40.0 Infective myocarditis	0.012	0.988
I41.8 Myocarditis in other diseases classified elsewhere	0.012	0.988
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.012	0.988
I41.1 Myocarditis in viral diseases classified elsewhere	0.012	0.988
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.012	0.988
I42.9 Cardiomyopathy, unspecified	0.012	0.988
I42.8 Other cardiomyopathies	0.012	0.988
I42.7 Cardiomyopathy due to drugs and other external agents	0.012	0.988
I42.6 Alcoholic cardiomyopathy	0.012	0.988
I42.5 Other restrictive cardiomyopathy	0.012	0.988
I42.4 Endocardial fibroelastosis	0.012	0.988
I42.3 Endomyocardial (eosinophilic) disease	0.012	0.988
I42.2 Other hypertrophic cardiomyopathy	0.012	0.988
I42.1 Obstructive hypertrophic cardiomyopathy	0.012	0.988
I42.0 Dilated cardiomyopathy	0.012	0.988
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.012	0.988
I43.2 Cardiomyopathy in nutritional diseases	0.012	0.988
I43.1 Cardiomyopathy in metabolic diseases	0.012	0.988
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.012	0.988
I46.9 Cardiac arrest, unspecified	0.012	0.988
I46.1 Sudden cardiac death, so described	0.012	0.988
I46.0 Cardiac arrest with successful resuscitation	0.012	0.988
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.012	0.988
I48.4 Atypical atrial flutter	0.012	0.988
I48.3 Typical atrial flutter	0.012	0.988
I48.2 Chronic atrial fibrillation	0.012	0.988
I48.1 Persistent atrial fibrillation	0.012	0.988
I48.0 Paroxysmal atrial fibrillation	0.012	0.988
I49.9 Cardiac arrhythmia, unspecified	0.012	0.988
I49.8 Other specified cardiac arrhythmias	0.012	0.988
I49.5 Sick sinus syndrome	0.012	0.988
I49.4 Other and unspecified premature depolarisation	0.012	0.988
I49.3 Ventricular premature depolarisation	0.012	0.988
I49.2 Junctional premature depolarisation	0.012	0.988
I49.1 Atrial premature depolarisation	0.012	0.988
I49.0 Ventricular fibrillation and flutter	0.012	0.988
I52.8 Other heart disorders in other diseases classified elsewhere	0.012	0.988
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.012	0.988
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.012	0.988
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.012	0.988
N70-N77 Inflammatory diseases of female pelvic organs	0.012	0.988
H55-H59 Other disorders of eye and adnexa	0.012	0.988
H53-H54 Visual disturbances and blindness	0.012	0.988
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.012	0.988
H46-H48 Disorders of optic nerve and visual pathways	0.012	0.988
H43-H45 Disorders of vitreous body and globe	0.012	0.988
H40-H42 Glaucoma	0.012	0.988
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.012	0.988
H10-H13 Disorders of conjunctiva	0.012	0.988
I80 Phlebitis and thrombophlebitis	0.012	0.988
M14 Arthropathies in other diseases classified elsewhere	0.012	0.988
M12 Other specific arthropathies	0.012	0.988
M11 Other crystal arthropathies	0.012	0.988
M09 Juvenile arthritis in diseases classified elsewhere	0.012	0.988
M08 Juvenile arthritis	0.012	0.988
M07 Psoriatic and enteropathic arthropathies	0.012	0.988
M05 Seropositive rheumatoid arthritis	0.012	0.988
N40-N51 Diseases of male genital organs	0.012	0.988
L80-L99 Other disorders of the skin and subcutaneous tissue	0.012	0.988
N99-N99 Other disorders of the genitourinary system	0.012	0.988
N60-N64 Disorders of breast	0.012	0.988
G50-G59 Nerve, nerve root and plexus disorders	0.012	0.988
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.011	0.988
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.011	0.988
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.011	0.988
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.011	0.988
T84.3 Mechanical complication of other bone devices, implants and grafts	0.011	0.988
T84.2 Mechanical complication of internal fixation device of other bones	0.011	0.988
T84.1 Mechanical complication of internal fixation device of bones of limb	0.011	0.988
G90-G99 Other disorders of the nervous system	0.011	0.988
G80-G83 Cerebral palsy and other paralytic syndromes	0.011	0.988
G70-G73 Diseases of myoneural junction and muscle	0.011	0.988
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.011	0.988
G35-G37 Demyelinating diseases of the central nervous system	0.011	0.988
G30-G32 Other degenerative diseases of the nervous system	0.011	0.988
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.011	0.988
G00-G09 Inflammatory diseases of the central nervous system	0.011	0.988
I73.9 Peripheral vascular disease, unspecified	0.011	0.988
F48 Other neurotic disorders	0.011	0.988
F45 Somatoform disorders	0.011	0.988
F44 Dissociative [conversion] disorders	0.011	0.988
F43 Reaction to severe stress, and adjustment disorders	0.011	0.988
F42 Obsessive-compulsive disorder	0.011	0.988
F40 Phobic anxiety disorders	0.011	0.988
I98 Other disorders of circulatory system in diseases classified elsewhere	0.011	0.988
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.011	0.988
I99 Other and unspecified disorders of circulatory system	0.011	0.988
H30-H36 Disorders of choroid and retina	0.011	0.988
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.011	0.988
M67 Other disorders of synovium and tendon	0.011	0.988
M66 Spontaneous rupture of synovium and tendon	0.011	0.988
M06 Other rheumatoid arthritis	0.011	0.989
M42 Spinal osteochondrosis	0.011	0.989
M41 Scoliosis	0.011	0.989
M40 Kyphosis and lordosis	0.011	0.989
I22.9 Subsequent myocardial infarction of unspecified site	0.011	0.989
I22.8 Subsequent myocardial infarction of other sites	0.011	0.989
I22.1 Subsequent myocardial infarction of inferior wall	0.011	0.989
I22.0 Subsequent myocardial infarction of anterior wall	0.011	0.989
I23.8 Other current complications following acute myocardial infarction	0.011	0.989
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.011	0.989
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.011	0.989
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.011	0.989
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.011	0.989
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.011	0.989
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.011	0.989
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.011	0.989
I24.9 Acute ischaemic heart disease, unspecified	0.011	0.989
I24.8 Other forms of acute ischaemic heart disease	0.011	0.989
I24.1 Dressler's syndrome	0.011	0.989
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.011	0.989
M20.5 Other deformities of toe(s) (acquired)	0.011	0.989
F10 Mental and behavioural disorders due to use of alcohol	0.011	0.989
M17.1 Other primary gonarthrosis	0.011	0.989
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.011	0.989
I88 Nonspecific lymphadenitis	0.011	0.989
I87 Other disorders of veins	0.011	0.989
I86 Varicose veins of other sites	0.011	0.989
I85 Oesophageal varices	0.011	0.989
I82 Other venous embolism and thrombosis	0.011	0.989
I81 Portal vein thrombosis	0.011	0.989
H02.8 Other specified disorders of eyelid	0.011	0.989
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.011	0.989
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.011	0.989
M79 Other soft tissue disorders, not elsewhere classified	0.011	0.989
I67.9 Cerebrovascular disease, unspecified	0.011	0.989
S01.9 Open wound of head, part unspecified	0.011	0.989
S01.7 Multiple open wounds of head	0.011	0.989
S01.5 Open wound of lip and oral cavity	0.011	0.989
S01.4 Open wound of cheek and temporomandibular area	0.011	0.989
S01.3 Open wound of ear	0.011	0.989
S01.2 Open wound of nose	0.011	0.989
S01.1 Open wound of eyelid and periocular area	0.011	0.989
B25-B34 Other viral diseases	0.011	0.989
M75.8 Other shoulder lesions	0.011	0.989
M75.9 Shoulder lesion, unspecified	0.011	0.989
M75.5 Bursitis of shoulder	0.011	0.989
M75.3 Calcific tendinitis of shoulder	0.011	0.989
M75.2 Bicipital tendinitis	0.011	0.989
M49 Spondylopathies in diseases classified elsewhere	0.011	0.989
M48 Other spondylopathies	0.011	0.989
M47 Spondylosis	0.011	0.989
M46 Other inflammatory spondylopathies	0.011	0.989
M45 Ankylosing spondylitis	0.011	0.989
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.011	0.989
M02 Reactive arthropathies	0.011	0.989
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.011	0.989
M00 Pyogenic arthritis	0.011	0.989
M63 Disorders of muscle in diseases classified elsewhere	0.011	0.989
M62 Other disorders of muscle	0.011	0.989
M61 Calcification and ossification of muscle	0.011	0.989
M60 Myositis	0.011	0.989
M90 Osteopathies in diseases classified elsewhere	0.011	0.989
M89 Other disorders of bone	0.011	0.989
M88 Paget's disease of bone [osteitis deformans]	0.011	0.989
M87 Osteonecrosis	0.011	0.989
M86 Osteomyelitis	0.011	0.989
M94 Other disorders of cartilage	0.011	0.989
M93 Other osteochondropathies	0.011	0.989
M92 Other juvenile osteochondrosis	0.011	0.989
M91 Juvenile osteochondrosis of hip and pelvis	0.011	0.989
M99 Biomechanical lesions, not elsewhere classified	0.011	0.989
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.011	0.989
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.011	0.989
B95-B98 Bacterial, viral and other infectious agents	0.011	0.989
H00 Hordeolum and chalazion	0.011	0.989
N02 Recurrent and persistent haematuria	0.011	0.989
S09.8 Other specified injuries of head	0.011	0.989
S09.7 Multiple injuries of head	0.011	0.989
S09.2 Traumatic rupture of ear drum	0.011	0.989
S09.1 Injury of muscle and tendon of head	0.011	0.989
S09.0 Injury of blood vessels of head, not elsewhere classified	0.011	0.989
P90-P96 Other disorders originating in the perinatal period	0.011	0.989
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.011	0.989
P75-P78 Digestive system disorders of fetus and newborn	0.011	0.989
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.011	0.989
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.011	0.989
P35-P39 Infections specific to the perinatal period	0.011	0.989
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.011	0.989
P10-P15 Birth trauma	0.011	0.989
P05-P08 Disorders related to length of gestation and fetal growth	0.011	0.989
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.011	0.989
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.011	0.989
Q80-Q89 Other congenital malformations	0.011	0.989
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.011	0.989

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations