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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3800316
log Bayes Factor = 57.3461
Chromosome 6   position 27,256,102  (GRCh37) Explore rs3800316 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.999 0.001 0.000
E16 Other disorders of pancreatic internal secretion
0.999 0.001 0.000
E16.2 Hypoglycaemia, unspecified
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
E10 Insulin-dependent diabetes mellitus
0.993 0.007 0.000
E03 Other hypothyroidism
0.992 0.008 0.000
E10.9 Without complications
0.987 0.013 0.000
E03.9 Hypothyroidism, unspecified
0.986 0.014 0.000
N40 Hyperplasia of prostate
0.000 0.022 0.978
E14 Unspecified diabetes mellitus
0.971 0.029 0.000
E20-E35 Disorders of other endocrine glands
0.937 0.063 0.000
E27 Other disorders of adrenal gland
0.926 0.074 0.000
E27.1 Primary adrenocortical insufficiency
0.898 0.102 0.000
E10.3 With ophthalmic complications
0.895 0.105 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.885 0.115 0.000
E14.9 Without complications
0.849 0.151 0.000
K90 Intestinal malabsorption
0.840 0.160 0.000
E13 Other specified diabetes mellitus
0.828 0.172 0.000
E14.3 With ophthalmic complications
0.827 0.173 0.000
E40-E46 Malnutrition
0.825 0.175 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.798 0.202 0.000
E14.6 With other specified complications
0.790 0.210 0.000
E14.1 With ketoacidosis
0.786 0.214 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.785 0.215 0.000
E14.2 Withrenal complications
0.764 0.236 0.000
E14.5 With peripheral circulatory complications
0.758 0.242 0.000
E31 Polyglandular dysfunction
0.753 0.247 0.000
E10.2 With renal complications
0.750 0.250 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.749 0.251 0.000
E16.1 Other hypoglycaemia
0.739 0.261 0.000
E34 Other endocrine disorders
0.734 0.266 0.000
E24 Cushing's syndrome
0.734 0.266 0.000
K90.9 Intestinal malabsorption, unspecified
0.729 0.271 0.000
E10.1 With ketoacidosis
0.729 0.271 0.000
E07 Other disorders of thyroid
0.729 0.271 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E10.5 With peripheral circulatory complications
0.717 0.283 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.716 0.284 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.716 0.284 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.716 0.284 0.000
E16.4 Abnormal secretion of gastrin
0.716 0.284 0.000
E16.3 Increased secretion of glucagon
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.714 0.286 0.000
E25 Adrenogenital disorders
0.713 0.287 0.000
E10.7 With multiple complications
0.712 0.288 0.000
E03.5 Myxoedema coma
0.712 0.288 0.000
E03.4 Atrophy of thyroid (acquired)
0.712 0.288 0.000
E03.3 Postinfectious hypothyroidism
0.712 0.288 0.000
E03.1 Congenital hypothyroidism without goitre
0.712 0.288 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.712 0.288 0.000
E13.9 Without complications
0.706 0.294 0.000
E10.6 With other specified complications
0.703 0.297 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.702 0.297 0.000
E46 Unspecified protein-energy malnutrition
0.700 0.300 0.000
E14.7 With multiple complications
0.696 0.304 0.000
E14.0 With coma
0.696 0.304 0.000
E20 Hypoparathyroidism
0.694 0.306 0.000
E03.8 Other specified hypothyroidism
0.686 0.314 0.000
E10.0 With coma
0.683 0.317 0.000
E05.8 Other thyrotoxicosis
0.681 0.319 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.679 0.321 0.000
E27.2 Addisonian crisis
0.678 0.322 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.672 0.328 0.000
E32 Diseases of thymus
0.672 0.328 0.000
E30 Disorders of puberty, not elsewhere classified
0.672 0.328 0.000
E14.4 With neurological complications
0.668 0.332 0.000
E14.8 With unspecified complications
0.666 0.334 0.000
E27.5 Adrenomedullary hyperfunction
0.664 0.336 0.000
E27.0 Other adrenocortical overactivity
0.664 0.336 0.000
E10.8 With unspecified complications
0.662 0.338 0.000
E24.2 Drug-induced Cushing's syndrome
0.652 0.348 0.000
E31.0 Autoimmune polyglandular failure
0.622 0.378 0.000
E34.9 Endocrine disorder, unspecified
0.619 0.381 0.000
E26 Hyperaldosteronism
0.615 0.385 0.000
K90.3 Pancreatic steatorrhoea
0.602 0.398 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.602 0.398 0.000
K90.1 Tropical sprue
0.602 0.398 0.000
E13.3 With ophthalmic complications
0.594 0.406 0.000
E13.8 With unspecified complications
0.594 0.406 0.000
E13.7 With multiple complications
0.594 0.406 0.000
E13.6 With other specified complications
0.594 0.406 0.000
E13.5 With peripheral circulatory complications
0.594 0.406 0.000
E13.4 With neurological complications
0.594 0.406 0.000
E13.2 With renal complications
0.594 0.406 0.000
E13.1 With ketoacidosis
0.594 0.406 0.000
E13.0 With coma
0.594 0.406 0.000
E27.9 Disorder of adrenal gland, unspecified
0.592 0.408 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.592 0.408 0.000
E45 Retarded development following protein-energy malnutrition
0.592 0.408 0.000
E43 Unspecified severe protein-energy malnutrition
0.592 0.408 0.000
E42 Marasmic kwashiorkor
0.592 0.408 0.000
E41 Nutritional marasmus
0.592 0.408 0.000
E40 Kwashiorkor
0.592 0.408 0.000
E23 Hypofunction and other disorders of pituitary gland
0.592 0.408 0.000
E22 Hyperfunction of pituitary gland
0.564 0.435 0.000
E34.8 Other specified endocrine disorders
0.563 0.437 0.000
E24.0 Pituitary-dependent Cushing's disease
0.557 0.443 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.553 0.447 0.000
E07.9 Disorder of thyroid, unspecified
0.553 0.447 0.000
E31.9 Polyglandular dysfunction, unspecified
0.540 0.460 0.000
E31.8 Other polyglandular dysfunction
0.540 0.460 0.000
E31.1 Polyglandular hyperfunction
0.540 0.460 0.000
E10.4 With neurological complications
0.536 0.464 0.000
E34.5 Androgen resistance syndrome
0.526 0.473 0.000
E34.4 Constitutional tall stature
0.526 0.473 0.000
E34.3 Short stature, not elsewhere classified
0.526 0.473 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.526 0.473 0.000
E34.1 Other hypersecretion of intestinal hormones
0.526 0.473 0.000
E24.8 Other Cushing's syndrome
0.526 0.473 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.526 0.473 0.000
E24.3 Ectopic ACTH syndrome
0.526 0.473 0.000
E24.1 Nelson's syndrome
0.526 0.473 0.000
E07.1 Dyshormogenetic goitre
0.522 0.477 0.000
E07.0 Hypersecretion of calcitonin
0.522 0.477 0.000
E20.9 Hypoparathyroidism, unspecified
0.520 0.480 0.000
E50-E64 Other nutritional deficiencies
0.517 0.483 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.513 0.487 0.000
E12.8 With unspecified complications
0.513 0.487 0.000
E12.7 With multiple complications
0.513 0.487 0.000
E12.6 With other specified complications
0.513 0.487 0.000
E12.5 With peripheral circulatory complications
0.513 0.487 0.000
E12.4 With neurological complications
0.513 0.487 0.000
E12.3 With ophthalmic complications
0.513 0.487 0.000
E12.2 With renal complications
0.513 0.487 0.000
E12.1 With ketoacidosis
0.513 0.487 0.000
E12.0 With coma
0.513 0.487 0.000
E25.9 Adrenogenital disorder, unspecified
0.511 0.488 0.000
E25.8 Other adrenogenital disorders
0.511 0.488 0.000
E07.8 Other specified disorders of thyroid
0.501 0.499 0.000
E20.8 Other hypoparathyroidism
0.498 0.502 0.000
E20.1 Pseudohypoparathyroidism
0.498 0.502 0.000
E20.0 Idiopathic hypoparathyroidism
0.498 0.502 0.000
E23.2 Diabetes insipidus
0.497 0.503 0.000
E28 Ovarian dysfunction
0.492 0.508 0.000
E06 Thyroiditis
0.491 0.509 0.000
E29 Testicular dysfunction
0.490 0.510 0.000
E30.9 Disorder of puberty, unspecified
0.482 0.518 0.000
E30.8 Other disorders of puberty
0.482 0.518 0.000
E30.1 Precocious puberty
0.482 0.518 0.000
E30.0 Delayed puberty
0.482 0.518 0.000
E32.9 Disease of thymus, unspecified
0.482 0.518 0.000
E32.8 Other diseases of thymus
0.482 0.518 0.000
E32.1 Abscess of thymus
0.482 0.518 0.000
E32.0 Persistent hyperplasia of thymus
0.482 0.518 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.482 0.518 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.482 0.518 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.482 0.518 0.000
E22.1 Hyperprolactinaemia
0.475 0.525 0.000
E27.8 Other specified disorders of adrenal gland
0.453 0.547 0.000
E26.9 Hyperaldosteronism, unspecified
0.441 0.559 0.000
E26.8 Other hyperaldosteronism
0.441 0.559 0.000
E26.1 Secondary hyperaldosteronism
0.441 0.559 0.000
E44.1 Mild protein-energy malnutrition
0.424 0.576 0.000
E44.0 Moderate protein-energy malnutrition
0.424 0.576 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.424 0.576 0.000
E23.1 Drug-induced hypopituitarism
0.424 0.576 0.000
K90.8 Other intestinal malabsorption
0.422 0.577 0.001
E34.0 Carcinoid syndrome
0.416 0.584 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.405 0.595 0.000
E22.8 Other hyperfunction of pituitary gland
0.405 0.595 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.399 0.601 0.000
E23.7 Disorder of pituitary gland, unspecified
0.386 0.614 0.000
E56 Other vitamin deficiencies
0.385 0.615 0.000
E26.0 Primary hyperaldosteronism
0.385 0.615 0.000
E51 Thiamine deficiency
0.382 0.618 0.000
E23.6 Other disorders of pituitary gland
0.377 0.623 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.371 0.629 0.000
E63 Other nutritional deficiencies
0.371 0.629 0.000
E50 Vitamin A deficiency
0.371 0.629 0.000
E60 Dietary zinc deficiency
0.371 0.629 0.000
E59 Dietary selenium deficiency
0.371 0.629 0.000
E54 Ascorbic acid deficiency
0.371 0.629 0.000
E52 Niacin deficiency [pellagra]
0.371 0.629 0.000
E61 Deficiency of other nutrient elements
0.365 0.635 0.000
E65-E68 Obesity and other hyperalimentation
0.355 0.645 0.000
E28.9 Ovarian dysfunction, unspecified
0.353 0.647 0.000
E28.8 Other ovarian dysfunction
0.353 0.647 0.000
E28.1 Androgen excess
0.353 0.647 0.000
E28.0 Oestrogen excess
0.353 0.647 0.000
E06.5 Other chronic thyroiditis
0.352 0.648 0.000
E06.4 Drug-induced thyroiditis
0.352 0.648 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.352 0.648 0.000
E06.1 Subacute thyroiditis
0.352 0.648 0.000
E06.0 Acute thyroiditis
0.352 0.648 0.000
E29.9 Testicular dysfunction, unspecified
0.351 0.648 0.000
E29.8 Other testicular dysfunction
0.351 0.648 0.000
E29.0 Testicular hyperfunction
0.351 0.648 0.000
E58 Dietary calcium deficiency
0.343 0.657 0.000
T42.4 Benzodiazepines
0.000 0.672 0.328
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.678 0.322
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.683 0.317
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.315 0.684 0.001
E23.0 Hypopituitarism
0.313 0.686 0.000
E55 Vitamin D deficiency
0.313 0.687 0.000
E24.9 Cushing's syndrome, unspecified
0.305 0.695 0.001
E28.3 Primary ovarian failure
0.298 0.701 0.000
E22.0 Acromegaly and pituitary gigantism
0.292 0.708 0.000
E56.1 Deficiency of vitamin K
0.290 0.710 0.000
E06.9 Thyroiditis, unspecified
0.287 0.713 0.000
E21.4 Other specified disorders of parathyroid gland
0.286 0.713 0.000
E21.2 Other hyperparathyroidism
0.286 0.713 0.000
E51.2 Wernicke's encephalopathy
0.285 0.714 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.284 0.716 0.000
E61.2 Magnesium deficiency
0.279 0.721 0.000
E53 Deficiency of other B group vitamins
0.278 0.722 0.000
E56.9 Vitamin deficiency, unspecified
0.276 0.724 0.000
E56.8 Deficiency of other vitamins
0.276 0.724 0.000
E56.0 Deficiency of vitamin E
0.276 0.724 0.000
E51.9 Thiamine deficiency, unspecified
0.274 0.726 0.000
E51.8 Other manifestations of thiamine deficiency
0.274 0.726 0.000
E51.1 Beriberi
0.274 0.726 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.730 0.270
T42.0 Hydantoin derivatives
0.000 0.733 0.267
E50.9 Vitamin A deficiency, unspecified
0.266 0.734 0.000
E50.8 Other manifestations of vitamin A deficiency
0.266 0.734 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.266 0.734 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.266 0.734 0.000
E50.5 Vitamin A deficiency with night blindness
0.266 0.734 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.266 0.734 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.266 0.734 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.266 0.734 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.266 0.734 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.266 0.734 0.000
E63.9 Nutritional deficiency, unspecified
0.266 0.734 0.000
E63.8 Other specified nutritional deficiencies
0.266 0.734 0.000
E63.1 Imbalance of constituents of food intake
0.266 0.734 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.266 0.734 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.266 0.734 0.000
E64.8 Sequelae of other nutritional deficiencies
0.266 0.734 0.000
E64.3 Sequelae of rickets
0.266 0.734 0.000
E64.2 Sequelae of vitamin C deficiency
0.266 0.734 0.000
E64.1 Sequelae of vitamin A deficiency
0.266 0.734 0.000
E64.0 Sequelae of protein-energy malnutrition
0.266 0.734 0.000
E28.2 Polycystic ovarian syndrome
0.263 0.737 0.000
E61.9 Deficiency of nutrient element, unspecified
0.262 0.738 0.000
E61.8 Deficiency of other specified nutrient elements
0.262 0.738 0.000
E61.7 Deficiency of multiple nutrient elements
0.262 0.738 0.000
E61.6 Vanadium deficiency
0.262 0.738 0.000
E61.5 Molybdenum deficiency
0.262 0.738 0.000
E61.4 Chromium deficiency
0.262 0.738 0.000
E61.3 Manganese deficiency
0.262 0.738 0.000
E61.0 Copper deficiency
0.262 0.738 0.000
E21.0 Primary hyperparathyroidism
0.256 0.744 0.000
E67 Other hyperalimentation
0.255 0.745 0.000
E68 Sequelae of hyperalimentation
0.255 0.745 0.000
N41 Inflammatory diseases of prostate
0.000 0.747 0.253
N41.1 Chronic prostatitis
0.000 0.748 0.252
N40-N51 Diseases of male genital organs
0.000 0.753 0.247
T42.1 Iminostilbenes
0.000 0.754 0.246
E21.3 Hyperparathyroidism, unspecified
0.245 0.755 0.000
E06.3 Autoimmune thyroiditis
0.243 0.757 0.000
N41.0 Acute prostatitis
0.000 0.758 0.242
E21.5 Disorder of parathyroid gland, unspecified
0.242 0.758 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.239 0.761 0.000
E61.1 Iron deficiency
0.235 0.765 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.769 0.231
T42.2 Succinimides and oxazolidinediones
0.000 0.769 0.231
E55.0 Rickets, active
0.224 0.775 0.000
E04 Other non-toxic goitre
0.216 0.784 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.786 0.214
E65 Localised adiposity
0.207 0.793 0.000
E53.1 Pyridoxine deficiency
0.200 0.800 0.000
E53.0 Riboflavin deficiency
0.200 0.800 0.000
E53.9 Vitamin B deficiency, unspecified
0.196 0.804 0.000
T42.3 Barbiturates
0.000 0.811 0.188
T39.1 4-Aminophenol derivatives
0.000 0.816 0.184
E67.8 Other specified hyperalimentation
0.183 0.817 0.000
E67.3 Hypervitaminosis D
0.183 0.817 0.000
E67.2 Megavitamin-B6 syndrome
0.183 0.817 0.000
E67.1 Hypercarotenaemia
0.183 0.817 0.000
E67.0 Hypervitaminosis A
0.183 0.817 0.000
N46 Male infertility
0.000 0.818 0.182
N41.3 Prostatocystitis
0.000 0.819 0.181
N41.2 Abscess of prostate
0.000 0.819 0.181
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.819 0.181
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.000 0.821 0.179
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.822 0.178
N51 Disorders of male genital organs in diseases classified elsewhere
0.000 0.822 0.177
E04.9 Non-toxic goitre, unspecified
0.174 0.825 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.829 0.171
N48 Other disorders of penis
0.000 0.829 0.171
E29.1 Testicular hypofunction
0.169 0.830 0.001
E55.9 Vitamin D deficiency, unspecified
0.166 0.834 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.000 0.843 0.157
T40.2 Other opioids
0.000 0.844 0.156
E04.8 Other specified non-toxic goitre
0.155 0.845 0.000
N41.8 Other inflammatory diseases of prostate
0.000 0.850 0.150
N44 Torsion of testis
0.000 0.854 0.145
N48.0 Leukoplakia of penis
0.000 0.857 0.143
N48.1 Balanoposthitis
0.000 0.857 0.143
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.857 0.143
N49.2 Inflammatory disorders of scrotum
0.000 0.859 0.141
N48.3 Priapism
0.000 0.859 0.141
T40.4 Other synthetic narcotics
0.000 0.860 0.140
N48.5 Ulcer of penis
0.000 0.862 0.138
N48.2 Other inflammatory disorders of penis
0.000 0.862 0.138
T40.6 Other and unspecified narcotics
0.000 0.863 0.137
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.865 0.135
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.867 0.133
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.870 0.130
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.870 0.129
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.871 0.129
E04.0 Non-toxic diffuse goitre
0.129 0.871 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.000 0.872 0.128
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.000 0.872 0.128
N49.0 Inflammatory disorders of seminal vesicle
0.000 0.872 0.128
T39.4 Antirheumatics, not elsewhere classified
0.000 0.872 0.128
T39.2 Pyrazolone derivatives
0.000 0.872 0.128
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.000 0.872 0.127
N51.2 Balanitis in diseases classified elsewhere
0.000 0.872 0.127
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.000 0.872 0.127
N51.0 Disorders of prostate in diseases classified elsewhere
0.000 0.872 0.127
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.873 0.127
T36 Poisoning by systemic antibiotics
0.000 0.873 0.127
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.877 0.123
T40.8 Lysergide [LSD]
0.000 0.877 0.123
T40.7 Cannabis (derivatives)
0.000 0.877 0.123
T40.5 Cocaine
0.000 0.877 0.123
T40.3 Methadone
0.000 0.877 0.123
T40.1 Heroin
0.000 0.877 0.123
T40.0 Opium
0.000 0.877 0.123
N45 Orchitis and epididymitis
0.000 0.879 0.121
N48.9 Disorder of penis, unspecified
0.000 0.879 0.121
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.879 0.121
T39.0 Salicylates
0.000 0.885 0.115
E83 Disorders of mineral metabolism
0.023 0.885 0.092
E53.8 Deficiency of other specified B group vitamins
0.114 0.886 0.000
N49.8 Inflammatory disorders of other specified male genital organs
0.000 0.886 0.113
N42 Other disorders of prostate
0.000 0.888 0.112
N48.4 Impotence of organic origin
0.000 0.892 0.108
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.895 0.104
E11 Non-insulin-dependent diabetes mellitus
0.103 0.897 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.897 0.103
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.897 0.103
N43 Hydrocele and spermatocele
0.000 0.899 0.101
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.903 0.097
T37.5 Antiviral drugs
0.000 0.903 0.097
T37.4 Anthelminthics
0.000 0.903 0.097
T37.3 Other antiprotozoal drugs
0.000 0.903 0.097
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.903 0.097
T37.1 Antimycobacterial drugs
0.000 0.903 0.097
T37.0 Sulphonamides
0.000 0.903 0.097
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.904 0.096
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.904 0.096
T47.7 Emetics
0.000 0.904 0.096
T47.6 Antidiarrhoeal drugs
0.000 0.904 0.096
T47.5 Digestants
0.000 0.904 0.096
T47.3 Saline and osmotic laxatives
0.000 0.904 0.096
T47.2 Stimulant laxatives
0.000 0.904 0.096
T47.0 Histamine H(2)-receptor antagonists
0.000 0.904 0.096
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.905 0.095
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.905 0.095
E11.6 With other specified complications
0.094 0.906 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.906 0.094
T41.5 Therapeutic gases
0.000 0.907 0.093
T41.4 Anaesthetic, unspecified
0.000 0.907 0.093
T41.3 Local anaesthetics
0.000 0.907 0.093
T41.2 Other and unspecified general anaesthetics
0.000 0.907 0.093
T41.1 Intravenous anaesthetics
0.000 0.907 0.093
T41.0 Inhaled anaesthetics
0.000 0.907 0.093
T50.8 Diagnostic agents
0.000 0.907 0.093
T50.7 Analeptics and opioid receptor antagonists
0.000 0.907 0.093
T50.5 Appetite depressants
0.000 0.907 0.093
T50.4 Drugs affecting uric acid metabolism
0.000 0.907 0.093
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.907 0.093
T50.1 Loop [high-ceiling] diuretics
0.000 0.907 0.093
T50.0 Mineralocorticoids and their antagonists
0.000 0.907 0.093
T49.9 Topical agent, unspecified
0.000 0.909 0.091
T49.8 Other topical agents
0.000 0.909 0.091
T49.7 Dental drugs, topically applied
0.000 0.909 0.091
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.909 0.091
T49.5 Ophthalmological drugs and preparations
0.000 0.909 0.091
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.909 0.091
T49.3 Emollients, demulcents and protectants
0.000 0.909 0.091
T49.2 Local astringents and local detergents
0.000 0.909 0.091
T49.1 Antipruritics
0.000 0.909 0.091
T36.9 Systemic antibiotic, unspecified
0.000 0.909 0.091
T36.8 Other systemic antibiotics
0.000 0.909 0.091
T36.7 Antifungal antibiotics, systemically used
0.000 0.909 0.091
T36.6 Rifamycins
0.000 0.909 0.091
T36.5 Aminoglycosides
0.000 0.909 0.091
T36.4 Tetracyclines
0.000 0.909 0.091
T36.3 Macrolides
0.000 0.909 0.091
T36.2 Chloramphenicol group
0.000 0.909 0.091
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.909 0.091
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.000 0.909 0.091
T47.4 Other laxatives
0.000 0.911 0.089
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.911 0.089
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.911 0.088
T36.0 Penicillins
0.000 0.912 0.088
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.913 0.087
T48.4 Expectorants
0.000 0.913 0.087
T48.3 Antitussives
0.000 0.913 0.087
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.913 0.087
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.913 0.087
T48.0 Oxytocic drugs
0.000 0.913 0.087
N42.0 Calculus of prostate
0.000 0.913 0.086
N42.1 Congestion and haemorrhage of prostate
0.000 0.915 0.085
E83.9 Disorder of mineral metabolism, unspecified
0.017 0.917 0.066
E83.8 Other disorders of mineral metabolism
0.017 0.917 0.066
E83.2 Disorders of zinc metabolism
0.017 0.917 0.066
E83.0 Disorders of copper metabolism
0.017 0.917 0.066
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.917 0.083
T48.5 Anti-common-cold drugs
0.000 0.918 0.082
E83.3 Disorders of phosphorus metabolism
0.008 0.919 0.072
N42.3 Dysplasia of prostate
0.000 0.919 0.080
T38.1 Thyroid hormones and substitutes
0.000 0.924 0.076
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.924 0.075
E11.2 With renal complications
0.074 0.926 0.000
E11.7 With multiple complications
0.074 0.926 0.000
T38.9 Other and unspecified hormone antagonists
0.000 0.926 0.074
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.926 0.074
T38.7 Androgens and anabolic congeners
0.000 0.926 0.074
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.926 0.074
T38.5 Other oestrogens and progestogens
0.000 0.926 0.074
T38.4 Oral contraceptives
0.000 0.926 0.074
T38.2 Antithyroid drugs
0.000 0.926 0.074
T38.0 Glucocorticoids and synthetic analogues
0.000 0.926 0.074
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.927 0.073
N43.0 Encysted hydrocele
0.000 0.927 0.073
N43.2 Other hydrocele
0.000 0.927 0.073
N42.2 Atrophy of prostate
0.000 0.928 0.072
N43.1 Infected hydrocele
0.000 0.929 0.071
E11.5 With peripheral circulatory complications
0.070 0.930 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.931 0.069
D12.2 Ascending colon
0.000 0.932 0.068
N43.4 Spermatocele
0.000 0.932 0.068
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.932 0.068
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.932 0.068
T46.7 Peripheral vasodilators
0.000 0.932 0.068
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.932 0.068
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.932 0.068
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.935 0.065
T46.1 Calcium-channel blockers
0.000 0.935 0.064
E11.0 With coma
0.064 0.936 0.000
N42.8 Other specified disorders of prostate
0.000 0.938 0.062
K90-K93 Other diseases of the digestive system
0.056 0.944 0.000
E11.8 With unspecified complications
0.055 0.945 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.945 0.054
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.945 0.054
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.945 0.054
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.945 0.054
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.945 0.054
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.945 0.054
T44.0 Anticholinesterase agents
0.000 0.945 0.054
E11.1 With ketoacidosis
0.054 0.946 0.000
E11.3 With ophthalmic complications
0.054 0.946 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.946 0.053
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.946 0.053
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.950 0.050
T45.8 Other primarily systemic and haematological agents
0.000 0.950 0.050
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.950 0.050
T45.6 Fibrinolysis-affecting drugs
0.000 0.950 0.050
T45.4 Iron and its compounds
0.000 0.950 0.050
T45.3 Enzymes, not elsewhere classified
0.000 0.950 0.050
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.951 0.048
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.951 0.048
T45.2 Vitamins, not elsewhere classified
0.000 0.952 0.048
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.000 0.953 0.047
D12.0 Caecum
0.000 0.953 0.047
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.956 0.043
E66 Obesity
0.042 0.958 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.958 0.042
R31 Unspecified haematuria
0.000 0.959 0.041
K93 Disorders of other digestive organs in diseases classified elsewhere
0.041 0.959 0.000
T45.5 Anticoagulants
0.000 0.960 0.040
D12.3 Transverse colon
0.000 0.960 0.040
D12.7 Rectosigmoid junction
0.000 0.960 0.040
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.960 0.039
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.961 0.039
N48.6 Balanitis xerotica obliterans
0.000 0.961 0.039
T45.0 Antiallergic and antiemetic drugs
0.000 0.963 0.037
E83.4 Disorders of magnesium metabolism
0.017 0.963 0.019
D12.9 Anus and anal canal
0.000 0.964 0.036
D12.1 Appendix
0.000 0.965 0.035
N47 Redundant prepuce, phimosis and paraphimosis
0.000 0.965 0.035
N50 Other disorders of male genital organs
0.000 0.967 0.033
E70-E90 Metabolic disorders
0.028 0.968 0.004
D12.4 Descending colon
0.000 0.968 0.032
E66.2 Extreme obesity with alveolar hypoventilation
0.031 0.969 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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