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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs380914
log Bayes Factor = 47.724
Chromosome 6   position 28,569,949  (GRCh37) Explore rs380914 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E83 Disorders of mineral metabolism
0.000 0.475 0.525
E83.3 Disorders of phosphorus metabolism
0.000 0.508 0.492
E83.4 Disorders of magnesium metabolism
0.000 0.620 0.380
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.623 0.377
E83.8 Other disorders of mineral metabolism
0.000 0.623 0.377
E83.2 Disorders of zinc metabolism
0.000 0.623 0.377
E83.0 Disorders of copper metabolism
0.000 0.623 0.377
K90 Intestinal malabsorption
0.314 0.686 0.000
E10.9 Without complications
0.275 0.725 0.000
E10 Insulin-dependent diabetes mellitus
0.273 0.727 0.000
E10.3 With ophthalmic complications
0.267 0.733 0.000
E10.4 With neurological complications
0.253 0.747 0.000
E10.6 With other specified complications
0.233 0.767 0.000
K90.8 Other intestinal malabsorption
0.230 0.770 0.000
K90.3 Pancreatic steatorrhoea
0.225 0.774 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.225 0.774 0.000
K90.1 Tropical sprue
0.225 0.774 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.222 0.777 0.000
E10.2 With renal complications
0.213 0.787 0.000
E10.1 With ketoacidosis
0.202 0.798 0.000
E10.0 With coma
0.185 0.815 0.000
E10.7 With multiple complications
0.180 0.819 0.000
E10.5 With peripheral circulatory complications
0.172 0.828 0.000
K90.9 Intestinal malabsorption, unspecified
0.165 0.835 0.000
E10.8 With unspecified complications
0.161 0.839 0.000
E10-E14 Diabetes mellitus
0.123 0.877 0.000
E05.9 Thyrotoxicosis, unspecified
0.119 0.881 0.000
E16.2 Hypoglycaemia, unspecified
0.101 0.899 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.097 0.903 0.000
E13 Other specified diabetes mellitus
0.096 0.904 0.000
E16 Other disorders of pancreatic internal secretion
0.095 0.905 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.092 0.908 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.090 0.910 0.000
E12 Malnutrition-related diabetes mellitus
0.088 0.912 0.000
E00-E07 Disorders of thyroid gland
0.083 0.917 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.082 0.917 0.000
E14 Unspecified diabetes mellitus
0.080 0.920 0.000
E40-E46 Malnutrition
0.079 0.921 0.000
E13.9 Without complications
0.076 0.924 0.000
E05.8 Other thyrotoxicosis
0.073 0.927 0.000
E46 Unspecified protein-energy malnutrition
0.071 0.929 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.070 0.930 0.000
E13.3 With ophthalmic complications
0.070 0.930 0.000
E05.5 Thyroid crisis or storm
0.069 0.931 0.000
E05.4 Thyrotoxicosis factitia
0.069 0.931 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.069 0.931 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.069 0.931 0.000
E13.8 With unspecified complications
0.069 0.931 0.000
E13.7 With multiple complications
0.069 0.931 0.000
E13.6 With other specified complications
0.069 0.931 0.000
E13.5 With peripheral circulatory complications
0.069 0.931 0.000
E13.4 With neurological complications
0.069 0.931 0.000
E13.2 With renal complications
0.069 0.931 0.000
E13.1 With ketoacidosis
0.069 0.931 0.000
E13.0 With coma
0.069 0.931 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.068 0.932 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.068 0.932 0.000
E16.4 Abnormal secretion of gastrin
0.068 0.932 0.000
E16.3 Increased secretion of glucagon
0.068 0.932 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.933 0.067
E15 Nondiabetic hypoglycaemic coma
0.066 0.934 0.000
E12.9 Without complications
0.063 0.936 0.000
E12.8 With unspecified complications
0.063 0.936 0.000
E12.7 With multiple complications
0.063 0.936 0.000
E12.6 With other specified complications
0.063 0.936 0.000
E12.5 With peripheral circulatory complications
0.063 0.936 0.000
E12.4 With neurological complications
0.063 0.936 0.000
E12.3 With ophthalmic complications
0.063 0.936 0.000
E12.2 With renal complications
0.063 0.936 0.000
E12.1 With ketoacidosis
0.063 0.936 0.000
E12.0 With coma
0.063 0.936 0.000
E14.4 With neurological complications
0.063 0.937 0.000
E14.3 With ophthalmic complications
0.062 0.938 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.059 0.940 0.000
E00 Congenital iodine-deficiency syndrome
0.059 0.940 0.000
E16.1 Other hypoglycaemia
0.059 0.941 0.000
E14.6 With other specified complications
0.058 0.942 0.000
E14.7 With multiple complications
0.058 0.942 0.000
E14.0 With coma
0.058 0.942 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.057 0.943 0.000
E45 Retarded development following protein-energy malnutrition
0.057 0.943 0.000
E43 Unspecified severe protein-energy malnutrition
0.057 0.943 0.000
E42 Marasmic kwashiorkor
0.057 0.943 0.000
E41 Nutritional marasmus
0.057 0.943 0.000
E40 Kwashiorkor
0.057 0.943 0.000
E14.2 Withrenal complications
0.056 0.944 0.000
E14.5 With peripheral circulatory complications
0.056 0.944 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.055 0.944 0.000
E14.1 With ketoacidosis
0.054 0.946 0.000
E50-E64 Other nutritional deficiencies
0.054 0.946 0.000
E06 Thyroiditis
0.053 0.947 0.000
E14.9 Without complications
0.053 0.947 0.000
E83.5 Disorders of calcium metabolism
0.000 0.950 0.050
E14.8 With unspecified complications
0.049 0.951 0.000
E80.4 Gilbert's syndrome
0.000 0.953 0.047
E07 Other disorders of thyroid
0.047 0.953 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.955 0.045
E70-E90 Metabolic disorders
0.001 0.956 0.043
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.043 0.957 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.043 0.957 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.043 0.957 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.043 0.957 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.043 0.957 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.043 0.957 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.043 0.957 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.043 0.957 0.000
E54 Ascorbic acid deficiency
0.042 0.958 0.000
E06.5 Other chronic thyroiditis
0.042 0.958 0.000
E44.1 Mild protein-energy malnutrition
0.041 0.959 0.000
E44.0 Moderate protein-energy malnutrition
0.041 0.959 0.000
E53 Deficiency of other B group vitamins
0.041 0.959 0.000
E06.9 Thyroiditis, unspecified
0.041 0.959 0.000
N50.8 Other specified disorders of male genital organs
0.040 0.960 0.000
E61 Deficiency of other nutrient elements
0.040 0.960 0.000
E56 Other vitamin deficiencies
0.039 0.961 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.039 0.961 0.000
E63 Other nutritional deficiencies
0.039 0.961 0.000
E50 Vitamin A deficiency
0.039 0.961 0.000
E60 Dietary zinc deficiency
0.039 0.961 0.000
E59 Dietary selenium deficiency
0.039 0.961 0.000
E52 Niacin deficiency [pellagra]
0.039 0.961 0.000
E06.4 Drug-induced thyroiditis
0.038 0.962 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.038 0.962 0.000
E06.0 Acute thyroiditis
0.038 0.962 0.000
E51 Thiamine deficiency
0.038 0.962 0.000
E80.1 Porphyria cutanea tarda
0.000 0.962 0.038
E07.8 Other specified disorders of thyroid
0.037 0.963 0.000
E06.1 Subacute thyroiditis
0.037 0.963 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.035 0.965 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.965 0.035
E85 Amyloidosis
0.000 0.965 0.034
E53.9 Vitamin B deficiency, unspecified
0.035 0.965 0.000
E07.1 Dyshormogenetic goitre
0.034 0.966 0.000
E07.0 Hypersecretion of calcitonin
0.034 0.966 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.967 0.033
E58 Dietary calcium deficiency
0.033 0.967 0.000
E61.1 Iron deficiency
0.033 0.967 0.000
E80.2 Other porphyria
0.000 0.967 0.033
E80.5 Crigler-Najjar syndrome
0.000 0.967 0.032
E80.3 Defects of catalase and peroxydase
0.000 0.967 0.032
E80.0 Hereditary erythropoietic porphyria
0.000 0.967 0.032
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.968 0.032
E77 Disorders of glycoprotein metabolism
0.001 0.969 0.031
E76 Disorders of glycosaminoglycan metabolism
0.001 0.969 0.031
E72 Other disorders of amino-acid metabolism
0.001 0.969 0.031
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.001 0.969 0.031
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.001 0.969 0.031
E80.6 Other disorders of bilirubin metabolism
0.000 0.969 0.031
E85.9 Amyloidosis, unspecified
0.000 0.970 0.030
E53.1 Pyridoxine deficiency
0.030 0.970 0.000
E53.0 Riboflavin deficiency
0.030 0.970 0.000
E74 Other disorders of carbohydrate metabolism
0.000 0.970 0.029
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.971 0.029
E61.9 Deficiency of nutrient element, unspecified
0.029 0.971 0.000
E61.8 Deficiency of other specified nutrient elements
0.029 0.971 0.000
E61.7 Deficiency of multiple nutrient elements
0.029 0.971 0.000
E61.6 Vanadium deficiency
0.029 0.971 0.000
E61.5 Molybdenum deficiency
0.029 0.971 0.000
E61.4 Chromium deficiency
0.029 0.971 0.000
E61.3 Manganese deficiency
0.029 0.971 0.000
E61.0 Copper deficiency
0.029 0.971 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.971 0.029
E56.1 Deficiency of vitamin K
0.028 0.971 0.000
E56.9 Vitamin deficiency, unspecified
0.028 0.972 0.000
E56.8 Deficiency of other vitamins
0.028 0.972 0.000
E56.0 Deficiency of vitamin E
0.028 0.972 0.000
S02.4 Fracture of malar and maxillary bones
0.028 0.972 0.000
E50.9 Vitamin A deficiency, unspecified
0.028 0.972 0.000
E50.8 Other manifestations of vitamin A deficiency
0.028 0.972 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.028 0.972 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.028 0.972 0.000
E50.5 Vitamin A deficiency with night blindness
0.028 0.972 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.028 0.972 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.028 0.972 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.028 0.972 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.028 0.972 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.028 0.972 0.000
E63.9 Nutritional deficiency, unspecified
0.028 0.972 0.000
E63.8 Other specified nutritional deficiencies
0.028 0.972 0.000
E63.1 Imbalance of constituents of food intake
0.028 0.972 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.028 0.972 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.028 0.972 0.000
E64.8 Sequelae of other nutritional deficiencies
0.028 0.972 0.000
E64.3 Sequelae of rickets
0.028 0.972 0.000
E64.2 Sequelae of vitamin C deficiency
0.028 0.972 0.000
E64.1 Sequelae of vitamin A deficiency
0.028 0.972 0.000
E64.0 Sequelae of protein-energy malnutrition
0.028 0.972 0.000
E65-E68 Obesity and other hyperalimentation
0.028 0.972 0.000
E51.9 Thiamine deficiency, unspecified
0.027 0.972 0.000
E51.8 Other manifestations of thiamine deficiency
0.027 0.972 0.000
E51.1 Beriberi
0.027 0.972 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.972 0.028
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.973 0.027
E73 Lactose intolerance
0.001 0.973 0.027
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.973 0.026
E51.2 Wernicke's encephalopathy
0.027 0.973 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.026 0.973 0.001
E85.3 Secondary systemic amyloidosis
0.000 0.974 0.025
E70.3 Albinism
0.000 0.974 0.025
E53.8 Deficiency of other specified B group vitamins
0.026 0.974 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.975 0.025
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.975 0.025
E79.1 Lesch-Nyhan syndrome
0.000 0.975 0.025
E85.8 Other amyloidosis
0.000 0.975 0.025
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.975 0.025
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.975 0.025
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.975 0.025
E84 Cystic fibrosis
0.001 0.975 0.024
E61.2 Magnesium deficiency
0.024 0.975 0.000
S02 Fracture of skull and facial bones
0.025 0.975 0.000
E55 Vitamin D deficiency
0.024 0.976 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.024 0.976 0.000
E89.1 Postprocedural hypoinsulinaemia
0.000 0.976 0.024
S02.8 Fractures of other skull and facial bones
0.024 0.976 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.976 0.024
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.976 0.024
E70.2 Disorders of tyrosine metabolism
0.000 0.976 0.024
E70.1 Other hyperphenylalaninaemias
0.000 0.976 0.024
E70.0 Classical phenylketonuria
0.000 0.976 0.024
E89.2 Postprocedural hypoparathyroidism
0.000 0.976 0.024
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.977 0.023
E89.5 Postprocedural testicular hypofunction
0.000 0.977 0.023
E06.3 Autoimmune thyroiditis
0.023 0.977 0.000
E71.3 Disorders of fatty-acid metabolism
0.001 0.977 0.022
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.001 0.977 0.022
E71.1 Other disorders of branched-chain amino-acid metabolism
0.001 0.977 0.022
E71.0 Maple-syrup-urine disease
0.001 0.977 0.022
E72.9 Disorder of amino-acid metabolism, unspecified
0.001 0.977 0.022
E72.8 Other specified disorders of amino-acid metabolism
0.001 0.977 0.022
E72.5 Disorders of glycine metabolism
0.001 0.977 0.022
E72.4 Disorders of ornithine metabolism
0.001 0.977 0.022
E72.3 Disorders of lysine and hydroxylysine metabolism
0.001 0.977 0.022
E72.2 Disorders of urea cycle metabolism
0.001 0.977 0.022
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.001 0.977 0.022
E72.0 Disorders of amino-acid transport
0.001 0.977 0.022
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.001 0.977 0.022
E76.8 Other disorders of glucosaminoglycan metabolism
0.001 0.977 0.022
E76.3 Mucopolysaccharidosis, unspecified
0.001 0.977 0.022
E76.2 Other mucopolysaccharidoses
0.001 0.977 0.022
E76.1 Mucopolysaccharidosis, type II
0.001 0.977 0.022
E76.0 Mucopolysaccharidosis, type I
0.001 0.977 0.022
E77.9 Disorder of glycoprotein metabolism, unspecified
0.001 0.977 0.022
E77.8 Other disorders of glycoprotein metabolism
0.001 0.977 0.022
E77.1 Defects in glycoprotein degradation
0.001 0.977 0.022
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.001 0.977 0.022
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.978 0.022
E89.4 Postprocedural ovarian failure
0.000 0.979 0.021
E74.9 Disorder of carbohydrate metabolism, unspecified
0.001 0.979 0.021
E74.8 Other specified disorders of carbohydrate metabolism
0.001 0.979 0.021
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.001 0.979 0.021
E74.2 Disorders of galactose metabolism
0.001 0.979 0.021
E74.1 Disorders of fructose metabolism
0.001 0.979 0.021
E74.0 Glycogen storage disease
0.001 0.979 0.021
E20-E35 Disorders of other endocrine glands
0.021 0.979 0.000
S02.2 Fracture of nasal bones
0.021 0.979 0.000
S02.3 Fracture of orbital floor
0.020 0.980 0.000
S02.5 Fracture of tooth
0.020 0.980 0.000
E67 Other hyperalimentation
0.020 0.980 0.000
E68 Sequelae of hyperalimentation
0.020 0.980 0.000
E20 Hypoparathyroidism
0.020 0.980 0.000
E85.4 Organ-limited amyloidosis
0.000 0.980 0.020
E73.8 Other lactose intolerance
0.001 0.980 0.019
E73.1 Secondary lactase deficiency
0.001 0.980 0.019
E73.0 Congenital lactase deficiency
0.001 0.980 0.019
E75.6 Lipid storage disorder, unspecified
0.001 0.980 0.019
E75.4 Neuronal ceroid lipofuscinosis
0.001 0.980 0.019
E75.3 Sphingolipidosis, unspecified
0.001 0.980 0.019
E75.1 Other gangliosidosis
0.001 0.980 0.019
E75.0 GM2 gangliosidosis
0.001 0.980 0.019
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.981 0.019
E20.9 Hypoparathyroidism, unspecified
0.019 0.981 0.000
E75.2 Other sphingolipidosis
0.001 0.981 0.018
E03 Other hypothyroidism
0.019 0.981 0.000
K90-K93 Other diseases of the digestive system
0.019 0.981 0.000
S02.0 Fracture of vault of skull
0.018 0.982 0.000
S02.20 Fracture of nasal bones (closed)
0.018 0.982 0.000
S02.41 Fracture of malar and maxillary bones (open)
0.018 0.982 0.000
S02.7 Multiple fractures involving skull and facial bones
0.018 0.982 0.000
E84.8 Cystic fibrosis with other manifestations
0.001 0.982 0.017
E84.1 Cystic fibrosis with intestinal manifestations
0.001 0.982 0.017
E55.0 Rickets, active
0.017 0.982 0.000
S02.30 Fracture of orbital floor (closed)
0.018 0.982 0.000
S02.81 Fractures of other skull and facial bones (open)
0.017 0.982 0.000
S02.50 Fracture of tooth (closed)
0.017 0.982 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.983 0.017
E84.0 Cystic fibrosis with pulmonary manifestations
0.001 0.983 0.016
E29 Testicular dysfunction
0.017 0.983 0.000
E24 Cushing's syndrome
0.016 0.984 0.000
E75.5 Other lipid storage disorders
0.001 0.984 0.015
E31 Polyglandular dysfunction
0.016 0.984 0.000
E73.9 Lactose intolerance, unspecified
0.000 0.984 0.015
E25 Adrenogenital disorders
0.015 0.984 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.015 0.985 0.000
E32 Diseases of thymus
0.015 0.985 0.000
E30 Disorders of puberty, not elsewhere classified
0.015 0.985 0.000
S02.21 Fracture of nasal bones (open)
0.015 0.985 0.000
S92.30 Fracture of metatarsal bone (closed)
0.015 0.985 0.000
E20.8 Other hypoparathyroidism
0.015 0.985 0.000
S02.31 Fracture of orbital floor (open)
0.015 0.985 0.000
S02.51 Fracture of tooth (open)
0.015 0.985 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.015 0.985 0.000
E67.8 Other specified hyperalimentation
0.014 0.985 0.000
E67.3 Hypervitaminosis D
0.014 0.985 0.000
E67.2 Megavitamin-B6 syndrome
0.014 0.985 0.000
E67.1 Hypercarotenaemia
0.014 0.985 0.000
E67.0 Hypervitaminosis A
0.014 0.985 0.000
E20.1 Pseudohypoparathyroidism
0.014 0.985 0.000
E20.0 Idiopathic hypoparathyroidism
0.014 0.985 0.000
E65 Localised adiposity
0.014 0.986 0.000
S02.00 Fracture of vault of skull (closed)
0.014 0.986 0.000
S02.1 Fracture of base of skull
0.014 0.986 0.000
E03.5 Myxoedema coma
0.014 0.986 0.000
E03.4 Atrophy of thyroid (acquired)
0.014 0.986 0.000
E03.3 Postinfectious hypothyroidism
0.014 0.986 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.013 0.986 0.000
S02.6 Fracture of mandible
0.014 0.986 0.000
S02.70 Multiple fractures involving skull and facial bones (closed)
0.013 0.986 0.000
E29.1 Testicular hypofunction
0.013 0.986 0.000
S02.01 Fracture of vault of skull (open)
0.013 0.987 0.000
E84.9 Cystic fibrosis, unspecified
0.001 0.987 0.012
S02.71 Multiple fractures involving skull and facial bones (open)
0.013 0.987 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.013 0.987 0.000
E24.0 Pituitary-dependent Cushing's disease
0.013 0.987 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.013 0.987 0.000
D50.8 Other iron deficiency anaemias
0.013 0.987 0.000
E88 Other metabolic disorders
0.001 0.988 0.012
S92.3 Fracture of metatarsal bone
0.012 0.988 0.000
E31.0 Autoimmune polyglandular failure
0.012 0.988 0.000
E24.2 Drug-induced Cushing's syndrome
0.012 0.988 0.000
E24.9 Cushing's syndrome, unspecified
0.012 0.988 0.000
E03.1 Congenital hypothyroidism without goitre
0.012 0.988 0.000
E29.8 Other testicular dysfunction
0.012 0.988 0.000
E29.0 Testicular hyperfunction
0.012 0.988 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.012 0.988 0.000
E24.3 Ectopic ACTH syndrome
0.012 0.988 0.000
E24.1 Nelson's syndrome
0.012 0.988 0.000
E34 Other endocrine disorders
0.012 0.988 0.000
E23 Hypofunction and other disorders of pituitary gland
0.012 0.988 0.000
E31.9 Polyglandular dysfunction, unspecified
0.012 0.988 0.000
E31.8 Other polyglandular dysfunction
0.012 0.988 0.000
E31.1 Polyglandular hyperfunction
0.012 0.988 0.000
E29.9 Testicular dysfunction, unspecified
0.012 0.988 0.000
E24.8 Other Cushing's syndrome
0.011 0.988 0.000
E26 Hyperaldosteronism
0.011 0.988 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.011 0.988 0.000
E25.9 Adrenogenital disorder, unspecified
0.011 0.989 0.000
E25.8 Other adrenogenital disorders
0.011 0.989 0.000
E07.9 Disorder of thyroid, unspecified
0.011 0.989 0.000
E30.9 Disorder of puberty, unspecified
0.011 0.989 0.000
E30.8 Other disorders of puberty
0.011 0.989 0.000
E30.1 Precocious puberty
0.011 0.989 0.000
E30.0 Delayed puberty
0.011 0.989 0.000
E32.9 Disease of thymus, unspecified
0.011 0.989 0.000
E32.8 Other diseases of thymus
0.011 0.989 0.000
E32.1 Abscess of thymus
0.011 0.989 0.000
E32.0 Persistent hyperplasia of thymus
0.011 0.989 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.011 0.989 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.011 0.989 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.011 0.989 0.000
I83 Varicose veins of lower extremities
0.000 0.989 0.011
E28 Ovarian dysfunction
0.011 0.989 0.000
R31 Unspecified haematuria
0.000 0.989 0.011
S02.91 Fracture of skull and facial bones, part unspecified (open)
0.011 0.989 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.011 0.989 0.000
E22 Hyperfunction of pituitary gland
0.011 0.989 0.000
E03.8 Other specified hypothyroidism
0.010 0.989 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.010 0.990 0.000
O04.9 Complete or unspecified, without complication
0.000 0.990 0.010
M07.30 Other psoriatic arthropathies (Multiple sites)
0.010 0.990 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.010 0.990 0.000
K93.1 Megacolon in Chagas' disease
0.010 0.990 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.010 0.990 0.000
S99.9 Unspecified injury of ankle and foot
0.010 0.990 0.000
S02.61 Fracture of mandible (open)
0.010 0.990 0.000
S92 Fracture of foot, except ankle
0.010 0.990 0.000
S02.11 Fracture of base of skull (open)
0.010 0.990 0.000
E88.8 Other specified metabolic disorders
0.001 0.990 0.009
E23.2 Diabetes insipidus
0.009 0.991 0.000
S92.31 Fracture of metatarsal bone (open)
0.009 0.991 0.000
S99 Other and unspecified injuries of ankle and foot
0.009 0.991 0.000
E21.4 Other specified disorders of parathyroid gland
0.009 0.991 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.000 0.991 0.009
E88.1 Lipodystrophy, not elsewhere classified
0.001 0.991 0.008
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.991 0.009
E23.7 Disorder of pituitary gland, unspecified
0.009 0.991 0.000
E34.9 Endocrine disorder, unspecified
0.009 0.991 0.000
S30.1 Contusion of abdominal wall
0.000 0.991 0.009
E34.5 Androgen resistance syndrome
0.009 0.991 0.000
E34.4 Constitutional tall stature
0.009 0.991 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.009 0.991 0.000
E34.1 Other hypersecretion of intestinal hormones
0.009 0.991 0.000
M07.3 Other psoriatic arthropathies
0.009 0.991 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.009 0.991 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.009 0.991 0.000
E23.1 Drug-induced hypopituitarism
0.009 0.991 0.000
E26.9 Hyperaldosteronism, unspecified
0.008 0.991 0.000
E26.8 Other hyperaldosteronism
0.008 0.991 0.000
E26.1 Secondary hyperaldosteronism
0.008 0.991 0.000
E34.3 Short stature, not elsewhere classified
0.008 0.991 0.000
E88.3 Tumour lysis syndrome
0.001 0.991 0.008
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.991 0.009
M13.0 Polyarthritis, unspecified
0.008 0.992 0.000
E34.8 Other specified endocrine disorders
0.008 0.992 0.000
E28.9 Ovarian dysfunction, unspecified
0.008 0.992 0.000
E28.8 Other ovarian dysfunction
0.008 0.992 0.000
E28.1 Androgen excess
0.008 0.992 0.000
E28.0 Oestrogen excess
0.008 0.992 0.000
O04 Medical abortion
0.000 0.992 0.008
M07.39 Other psoriatic arthropathies (Site unspecified)
0.008 0.992 0.000
E27 Other disorders of adrenal gland
0.008 0.992 0.000
S90-S99 Injuries to the ankle and foot
0.008 0.992 0.000
S92.9 Fracture of foot, unspecified
0.008 0.992 0.000
E21.2 Other hyperparathyroidism
0.008 0.992 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.008 0.992 0.000
E22.8 Other hyperfunction of pituitary gland
0.008 0.992 0.000
E04 Other non-toxic goitre
0.008 0.992 0.000
E23.6 Other disorders of pituitary gland
0.008 0.992 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.007 0.992 0.000
E21.3 Hyperparathyroidism, unspecified
0.008 0.992 0.000
M13.09 Polyarthritis, unspecified (Site unspecified)
0.008 0.992 0.000
S92.0 Fracture of calcaneus
0.008 0.992 0.000
S90 Superficial injury of ankle and foot
0.008 0.992 0.000
S92.4 Fracture of great toe
0.008 0.992 0.000
M07.38 Other psoriatic arthropathies (Other)
0.008 0.992 0.000
S90.8 Other superficial injuries of ankle and foot
0.008 0.992 0.000
E28.3 Primary ovarian failure
0.007 0.992 0.000
S92.2 Fracture of other tarsal bone(s)
0.007 0.993 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.007 0.993 0.000
S92.1 Fracture of talus
0.007 0.993 0.000
S92.7 Multiple fractures of foot
0.007 0.993 0.000
E88.2 Lipomatosis, not elsewhere classified
0.001 0.993 0.006
S99.8 Other specified injuries of ankle and foot
0.007 0.993 0.000
S92.5 Fracture of other toe
0.007 0.993 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.007 0.993 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.007 0.993 0.000
O04.8 Complete or unspecified, with other and unspecified complications
0.000 0.993 0.007
E21.5 Disorder of parathyroid gland, unspecified
0.007 0.993 0.000
M13.06 Polyarthritis, unspecified (Lower leg)
0.007 0.993 0.000
S92.90 Fracture of foot, unspecified (closed)
0.007 0.993 0.000
E88.9 Metabolic disorder, unspecified
0.001 0.993 0.006
S99.7 Multiple injuries of ankle and foot
0.007 0.993 0.000
E22.1 Hyperprolactinaemia
0.007 0.993 0.000
L43.9 Lichen planus, unspecified
0.007 0.993 0.000
E34.0 Carcinoid syndrome
0.006 0.993 0.000
M45 Ankylosing spondylitis
0.000 0.993 0.007
S02.10 Fracture of base of skull (closed)
0.007 0.993 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.006 0.993 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.006 0.993 0.000
E27.9 Disorder of adrenal gland, unspecified
0.007 0.993 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.007 0.993 0.000
E27.1 Primary adrenocortical insufficiency
0.006 0.994 0.000
M13.08 Polyarthritis, unspecified (Other)
0.006 0.994 0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.006 0.994 0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.006 0.994 0.000
M13.03 Polyarthritis, unspecified (Forearm)
0.006 0.994 0.000
M13.02 Polyarthritis, unspecified (Upper arm)
0.006 0.994 0.000
M13.01 Polyarthritis, unspecified (Shoulder region)
0.006 0.994 0.000
E27.2 Addisonian crisis
0.006 0.994 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.994 0.006
O04.7 Complete or unspecified, complicated by embolism
0.000 0.994 0.006
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.994 0.006
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.994 0.006
O04.3 Incomplete, with other and unspecified complications
0.000 0.994 0.006
O04.2 Incomplete, complicated by embolism
0.000 0.994 0.006
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.994 0.006
E27.5 Adrenomedullary hyperfunction
0.006 0.994 0.000
E27.0 Other adrenocortical overactivity
0.006 0.994 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.006 0.994 0.000
S98 Traumatic amputation of ankle and foot
0.006 0.994 0.000
S95 Injury of blood vessels at ankle and foot level
0.006 0.994 0.000
S94 Injury of nerves at ankle and foot level
0.006 0.994 0.000
S92.91 Fracture of foot, unspecified (open)
0.006 0.994 0.000
S92.00 Fracture of calcaneus (closed)
0.006 0.994 0.000
E04.8 Other specified non-toxic goitre
0.006 0.994 0.000
S92.40 Fracture of great toe (closed)
0.006 0.994 0.000
L40 Psoriasis
0.006 0.994 0.000
N50 Other disorders of male genital organs
0.006 0.994 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.006 0.994 0.000
S92.41 Fracture of great toe (open)
0.006 0.994 0.000
S97 Crushing injury of ankle and foot
0.006 0.994 0.000
S92.01 Fracture of calcaneus (open)
0.006 0.994 0.000
S90.1 Contusion of toe(s) without damage to nail
0.006 0.994 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.006 0.994 0.000
S90.2 Contusion of toe(s) with damage to nail
0.006 0.994 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.994 0.006
S02.60 Fracture of mandible (closed)
0.006 0.994 0.000
M07 Psoriatic and enteropathic arthropathies
0.006 0.994 0.000
L40.5 Arthropathic psoriasis
0.006 0.994 0.000
S90.0 Contusion of ankle
0.006 0.994 0.000
S92.50 Fracture of other toe (closed)
0.006 0.994 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.006 0.994 0.000
L40.4 Guttate psoriasis
0.005 0.994 0.000
S92.21 Fracture of other tarsal bone(s) (open)
0.005 0.994 0.000
S92.11 Fracture of talus (open)
0.005 0.995 0.000
L40.0 Psoriasis vulgaris
0.005 0.995 0.000
S92.71 Multiple fractures of foot (open)
0.005 0.995 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.005 0.995 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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