TreeWAS – Variant ID: rs3811321

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.1 Aortic (valve) insufficiency	0.033	0.967	0.000
I35 Nonrheumatic aortic valve disorders	0.033	0.967	0.000
I50 Heart failure	0.032	0.968	0.000
I30-I52 Other forms of heart disease	0.032	0.968	0.000
I50.0 Congestive heart failure	0.032	0.968	0.000
I34 Nonrheumatic mitral valve disorders	0.031	0.969	0.000
I33 Acute and subacute endocarditis	0.030	0.970	0.000
I34.1 Mitral (valve) prolapse	0.030	0.970	0.000
I33.0 Acute and subacute infective endocarditis	0.029	0.971	0.000
I46 Cardiac arrest	0.029	0.971	0.000
I50.9 Heart failure, unspecified	0.028	0.972	0.000
I51 Complications and ill-defined descriptions of heart disease	0.028	0.972	0.000
I35.0 Aortic (valve) stenosis	0.028	0.972	0.000
I35.8 Other aortic valve disorders	0.026	0.974	0.000
I51.7 Cardiomegaly	0.026	0.974	0.000
I46.0 Cardiac arrest with successful resuscitation	0.025	0.975	0.000
I49 Other cardiac arrhythmias	0.025	0.975	0.000
I35.9 Aortic valve disorder, unspecified	0.024	0.976	0.000
I47 Paroxysmal tachycardia	0.024	0.976	0.000
I52 Other heart disorders in diseases classified elsewhere	0.023	0.977	0.000
I48 Atrial fibrillation and flutter	0.023	0.977	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.023	0.977	0.000
I41 Myocarditis in diseases classified elsewhere	0.023	0.977	0.000
I40 Acute myocarditis	0.023	0.977	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.023	0.977	0.000
I32 Pericarditis in diseases classified elsewhere	0.023	0.977	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.977	0.023
I51.8 Other ill-defined heart diseases	0.023	0.977	0.000
I46.9 Cardiac arrest, unspecified	0.023	0.977	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.977	0.023
I31 Other diseases of pericardium	0.023	0.977	0.000
I36 Nonrheumatic tricuspid valve disorders	0.022	0.978	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.022	0.978	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.022	0.978	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.022	0.978	0.000
I33.9 Acute endocarditis, unspecified	0.022	0.978	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.022	0.978	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.978	0.022
I49.4 Other and unspecified premature depolarisation	0.022	0.978	0.000
I51.6 Cardiovascular disease, unspecified	0.021	0.979	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.979	0.021
I37 Pulmonary valve disorders	0.021	0.979	0.000
C34.0 Main bronchus	0.000	0.979	0.021
I46.1 Sudden cardiac death, so described	0.021	0.979	0.000
I51.5 Myocardial degeneration	0.020	0.980	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.020	0.980	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.020	0.980	0.000
I47.1 Supraventricular tachycardia	0.020	0.980	0.000
I49.3 Ventricular premature depolarisation	0.020	0.980	0.000
I34.0 Mitral (valve) insufficiency	0.020	0.980	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.020	0.980	0.000
I51.4 Myocarditis, unspecified	0.020	0.980	0.000
I30 Acute pericarditis	0.020	0.980	0.000
I50.1 Left ventricular failure	0.020	0.980	0.000
I51.0 Cardiac septal defect, acquired	0.019	0.981	0.000
I38 Endocarditis, valve unspecified	0.019	0.981	0.000
I49.8 Other specified cardiac arrhythmias	0.019	0.981	0.000
C34.2 Middle lobe, bronchus or lung	0.000	0.981	0.018
I31.3 Pericardial effusion (noninflammatory)	0.018	0.982	0.000
I47.0 Reentry ventricular arrhythmia	0.018	0.982	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.018	0.982	0.000
I49.2 Junctional premature depolarisation	0.018	0.982	0.000
I49.5 Sick sinus syndrome	0.018	0.982	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.018	0.982	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.017	0.983	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.017	0.983	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.017	0.983	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.017	0.983	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.017	0.983	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.017	0.983	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.017	0.983	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.017	0.983	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.017	0.983	0.000
I40.9 Acute myocarditis, unspecified	0.017	0.983	0.000
I40.8 Other acute myocarditis	0.017	0.983	0.000
I40.1 Isolated myocarditis	0.017	0.983	0.000
I40.0 Infective myocarditis	0.017	0.983	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.017	0.983	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.017	0.983	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.017	0.983	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.017	0.983	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.017	0.983	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.017	0.983	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.017	0.983	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.017	0.983	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.017	0.983	0.000
I48.4 Atypical atrial flutter	0.017	0.983	0.000
I48.3 Typical atrial flutter	0.017	0.983	0.000
I48.2 Chronic atrial fibrillation	0.017	0.983	0.000
I48.1 Persistent atrial fibrillation	0.017	0.983	0.000
I48.0 Paroxysmal atrial fibrillation	0.017	0.983	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.017	0.983	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.017	0.983	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.017	0.983	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.983	0.017
I49.0 Ventricular fibrillation and flutter	0.017	0.983	0.000
M06.9 Rheumatoid arthritis, unspecified	0.017	0.983	0.000
I31.8 Other specified diseases of pericardium	0.016	0.983	0.000
I31.2 Haemopericardium, not elsewhere classified	0.016	0.983	0.000
I31.1 Chronic constrictive pericarditis	0.016	0.983	0.000
I31.0 Chronic adhesive pericarditis	0.016	0.983	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.016	0.984	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.016	0.984	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.016	0.984	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.016	0.984	0.000
I49.1 Atrial premature depolarisation	0.016	0.984	0.000
I44 Atrioventricular and left bundle-branch block	0.016	0.984	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.015	0.985	0.000
I37.9 Pulmonary valve disorder, unspecified	0.015	0.985	0.000
I37.8 Other pulmonary valve disorders	0.015	0.985	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.015	0.985	0.000
I37.0 Pulmonary valve stenosis	0.015	0.985	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.015	0.985	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.015	0.985	0.000
I42 Cardiomyopathy	0.014	0.985	0.000
I30.8 Other forms of acute pericarditis	0.014	0.986	0.000
I30.1 Infective pericarditis	0.014	0.986	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.014	0.986	0.000
I51.9 Heart disease, unspecified	0.014	0.986	0.000
I44.2 Atrioventricular block, complete	0.014	0.986	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.014	0.986	0.000
I49.9 Cardiac arrhythmia, unspecified	0.013	0.987	0.000
I44.3 Other and unspecified atrioventricular block	0.013	0.987	0.000
I37.1 Pulmonary valve insufficiency	0.013	0.987	0.000
I31.9 Disease of pericardium, unspecified	0.013	0.987	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.012	0.988	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.012	0.988	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.012	0.988	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.012	0.988	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.012	0.988	0.000
I44.5 Left posterior fascicular block	0.011	0.988	0.000
I44.4 Left anterior fascicular block	0.011	0.988	0.000
I42.9 Cardiomyopathy, unspecified	0.011	0.989	0.000
I42.6 Alcoholic cardiomyopathy	0.011	0.989	0.000
Z95.4 Presence of other heart-valve replacement	0.011	0.989	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.011	0.989	0.000
I42.5 Other restrictive cardiomyopathy	0.011	0.989	0.000
I42.4 Endocardial fibroelastosis	0.011	0.989	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.011	0.989	0.000
I30.9 Acute pericarditis, unspecified	0.010	0.989	0.000
I44.6 Other and unspecified fascicular block	0.010	0.990	0.000
I47.2 Ventricular tachycardia	0.010	0.990	0.000
M06 Other rheumatoid arthritis	0.009	0.991	0.000
I45 Other conduction disorders	0.009	0.991	0.000
I42.0 Dilated cardiomyopathy	0.009	0.991	0.000
I42.8 Other cardiomyopathies	0.009	0.991	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.009	0.991	0.000
I44.1 Atrioventricular block, second degree	0.009	0.991	0.000
I44.0 Atrioventricular block, first degree	0.009	0.991	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.008	0.991	0.000
I42.2 Other hypertrophic cardiomyopathy	0.008	0.992	0.000
M06.3 Rheumatoid nodule	0.007	0.992	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.993	0.007
I45.3 Trifascicular block	0.007	0.993	0.000
I45.2 Bifascicular block	0.007	0.993	0.000
M06.8 Other specified rheumatoid arthritis	0.007	0.993	0.000
M06.4 Inflammatory polyarthropathy	0.007	0.993	0.000
M06.2 Rheumatoid bursitis	0.007	0.993	0.000
M06.1 Adult-onset Still's disease	0.007	0.993	0.000
M06.0 Seronegative rheumatoid arthritis	0.007	0.993	0.000
I45.4 Nonspecific intraventricular block	0.007	0.993	0.000
I45.0 Right fascicular block	0.007	0.993	0.000
I72.8 Aneurysm of other specified arteries	0.007	0.993	0.000
Q27.3 Peripheral arteriovenous malformation	0.007	0.993	0.000
Q27 Other congenital malformations of peripheral vascular system	0.006	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
I45.9 Conduction disorder, unspecified	0.006	0.994	0.000
I45.8 Other specified conduction disorders	0.006	0.994	0.000
M06.34 Rheumatoid nodule (Hand)	0.006	0.994	0.000
I71 Aortic aneurysm and dissection	0.006	0.994	0.000
I72 Other aneurysm	0.006	0.994	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.006	0.994	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.006	0.994	0.000
I45.5 Other specified heart block	0.006	0.994	0.000
I81 Portal vein thrombosis	0.006	0.994	0.000
Q28 Other congenital malformations of circulatory system	0.006	0.994	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.994	0.006
I44.7 Left bundle-branch block, unspecified	0.006	0.994	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.006	0.994	0.000
M06.38 Rheumatoid nodule (Other)	0.006	0.994	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.006	0.994	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.006	0.994	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.006	0.994	0.000
M06.33 Rheumatoid nodule (Forearm)	0.006	0.994	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.006	0.994	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.006	0.994	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.006	0.994	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.006	0.994	0.000
Chapter IX Diseases of the circulatory system	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.994	0.005
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.994	0.005
C31 Malignant neoplasm of accessory sinuses	0.000	0.994	0.005
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.994	0.005
C37 Malignant neoplasm of thymus	0.000	0.994	0.005
C33 Malignant neoplasm of trachea	0.000	0.994	0.005
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.006	0.994	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.005	0.994	0.000
Q23 Congenital malformations of aortic and mitral valves	0.005	0.994	0.000
O03.4 Incomplete, without complication	0.000	0.995	0.005
I27 Other pulmonary heart diseases	0.005	0.995	0.000
K92.0 Haematemesis	0.000	0.995	0.005
N20.2 Calculus of kidney with calculus of ureter	0.005	0.995	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.005	0.995	0.000
I45.6 Preexcitation syndrome	0.005	0.995	0.000
N20 Calculus of kidney and ureter	0.005	0.995	0.000
N23 Unspecified renal colic	0.005	0.995	0.000
I72.4 Aneurysm of artery of lower extremity	0.005	0.995	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.005	0.995	0.000
M06.18 Adult-onset Still's disease (Other)	0.005	0.995	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.005	0.995	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.005	0.995	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.005	0.995	0.000
M06.14 Adult-onset Still's disease (Hand)	0.005	0.995	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.005	0.995	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.005	0.995	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.005	0.995	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.005	0.995	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.005	0.995	0.000
M06.28 Rheumatoid bursitis (Other)	0.005	0.995	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.005	0.995	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.005	0.995	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.005	0.995	0.000
M06.24 Rheumatoid bursitis (Hand)	0.005	0.995	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.005	0.995	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.005	0.995	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.005	0.995	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.005	0.995	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.005	0.995	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.005	0.995	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.005	0.995	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.005	0.995	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.005	0.995	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.005	0.995	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.005	0.995	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.005	0.995	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.005	0.995	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.005	0.995	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.005	0.995	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.005	0.995	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.005	0.995	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.005	0.995	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.005	0.995	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.005	0.995	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.005	0.995	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.005	0.995	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.005	0.995	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.005	0.995	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.005	0.995	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.005	0.995	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.005	0.995	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.005	0.995	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.005	0.995	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.005	0.995	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.005	0.995	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.005	0.995	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.005	0.995	0.000
I86 Varicose veins of other sites	0.005	0.995	0.000
I27.0 Primary pulmonary hypertension	0.005	0.995	0.000
I71.0 Dissection of aorta [any part]	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
I86.4 Gastric varices	0.005	0.995	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.005	0.995	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.005	0.995	0.000
I74 Arterial embolism and thrombosis	0.005	0.995	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.005	0.995	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.995	0.005
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.005	0.995	0.000
I27.2 Other secondary pulmonary hypertension	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.005	0.995	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.005	0.995	0.000
Q27.4 Congenital phlebectasia	0.005	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.005	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.005	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.005	0.995	0.000
Q25.1 Coarctation of aorta	0.005	0.995	0.000
I74.8 Embolism and thrombosis of other arteries	0.005	0.995	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.005	0.995	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.005	0.995	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.005	0.995	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.005	0.995	0.000
I72.9 Aneurysm of unspecified site	0.005	0.995	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.005	0.995	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.005	0.995	0.000
I72.2 Aneurysm of renal artery	0.005	0.995	0.000
I72.1 Aneurysm of artery of upper extremity	0.005	0.995	0.000
N20.9 Urinary calculus, unspecified	0.005	0.995	0.000
N20.1 Calculus of ureter	0.005	0.995	0.000
Q21 Congenital malformations of cardiac septa	0.005	0.995	0.000
I80 Phlebitis and thrombophlebitis	0.005	0.995	0.000
K70 Alcoholic liver disease	0.000	0.995	0.005
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.005	0.995	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.995	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.995	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.995	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.995	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.995	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.004	0.995	0.000
I85 Oesophageal varices	0.004	0.995	0.000
N20-N23 Urolithiasis	0.005	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
I27.9 Pulmonary heart disease, unspecified	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
I72.0 Aneurysm of carotid artery	0.004	0.996	0.000
I78 Diseases of capillaries	0.004	0.996	0.000
C32 Malignant neoplasm of larynx	0.000	0.996	0.004
I00-I02 Acute rheumatic fever	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
Q25.3 Stenosis of aorta	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.004	0.996	0.000
C30.1 Middle ear	0.000	0.996	0.004
C30.0 Nasal cavity	0.000	0.996	0.004
C31.9 Accessory sinus, unspecified	0.000	0.996	0.004
C31.8 Overlapping lesion of accessory sinuses	0.000	0.996	0.004
C31.3 Sphenoidal sinus	0.000	0.996	0.004
C31.2 Frontal sinus	0.000	0.996	0.004
C31.1 Ethmoidal sinus	0.000	0.996	0.004
C31.0 Maxillary sinus	0.000	0.996	0.004
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.996	0.004
C38.4 Pleura	0.000	0.996	0.004
C38.3 Mediastinum, part unspecified	0.000	0.996	0.004
C38.2 Posterior mediastinum	0.000	0.996	0.004
C38.1 Anterior mediastinum	0.000	0.996	0.004
C38.0 Heart	0.000	0.996	0.004
C39.9 Ill-defined sites within the respiratory system	0.000	0.996	0.004
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.996	0.004
C39.0 Upper respiratory tract, part unspecified	0.000	0.996	0.004
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.004	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.004	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.004	0.996	0.000
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
Q23.2 Congenital mitral stenosis	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
I86.1 Scrotal varices	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
O03 Spontaneous abortion	0.000	0.996	0.004
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
I27.1 Kyphoscoliotic heart disease	0.004	0.996	0.000
I85.0 Oesophageal varices with bleeding	0.004	0.996	0.000
I86.8 Varicose veins of other specified sites	0.004	0.996	0.000
O03.9 Complete or unspecified, without complication	0.000	0.996	0.004
I77 Other disorders of arteries and arterioles	0.004	0.996	0.000
I27.8 Other specified pulmonary heart diseases	0.004	0.996	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.004	0.996	0.000
I82 Other venous embolism and thrombosis	0.004	0.996	0.000
I86.3 Vulval varices	0.004	0.996	0.000
I86.2 Pelvic varices	0.004	0.996	0.000
I86.0 Sublingual varices	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.004	0.996	0.000
W19.2 School, other institution and public administrative area	0.000	0.996	0.004
I87 Other disorders of veins	0.004	0.996	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.004	0.996	0.000
I72.3 Aneurysm of iliac artery	0.004	0.996	0.000
N20.0 Calculus of kidney	0.004	0.996	0.000
Q65 Congenital deformities of hip	0.004	0.996	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.004	0.996	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.004	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.004	0.996	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.004	0.996	0.000
I88 Nonspecific lymphadenitis	0.004	0.996	0.000
Q39 Congenital malformations of oesophagus	0.004	0.996	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.004	0.996	0.000
I28 Other diseases of pulmonary vessels	0.004	0.996	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.004	0.996	0.000
Q35-Q37 Cleft lip and cleft palate	0.004	0.996	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.004	0.996	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.004	0.996	0.000
Z96.0 Presence of urogenital implants	0.000	0.996	0.004
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.004	0.996	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.004	0.996	0.000
I82.8 Embolism and thrombosis of other specified veins	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.004	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.004	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.004	0.996	0.000
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.004	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.004	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.004	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.004	0.996	0.000
Q22.0 Pulmonary valve atresia	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
L57.0 Actinic keratosis	0.004	0.996	0.000
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.000	0.996	0.004
I70 Atherosclerosis	0.003	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
Q45 Other congenital malformations of digestive system	0.004	0.996	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.004	0.996	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.004	0.996	0.000
Q40 Other congenital malformations of upper alimentary tract	0.004	0.996	0.000
Q05 Spina bifida	0.004	0.996	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.004	0.996	0.000
I78.8 Other diseases of capillaries	0.004	0.996	0.000
Q65.8 Other congenital deformities of hip	0.004	0.996	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.003	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.003	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.003	0.996	0.000
Q21.3 Tetralogy of Fallot	0.003	0.996	0.000
Q21.2 Atrioventricular septal defect	0.003	0.996	0.000
Q82 Other congenital malformations of skin	0.003	0.996	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.996	0.003
Q50-Q56 Congenital malformations of genital organs	0.003	0.996	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.996	0.000
I73.9 Peripheral vascular disease, unspecified	0.004	0.996	0.000
K70.0 Alcoholic fatty liver	0.000	0.996	0.003
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.004	0.996	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.996	0.000
I79.1 Aortitis in diseases classified elsewhere	0.003	0.996	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.003	0.996	0.000
I87.8 Other specified disorders of veins	0.003	0.996	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.003	0.996	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
I74.5 Embolism and thrombosis of iliac artery	0.003	0.997	0.000
I78.9 Disease of capillaries, unspecified	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
C32.8 Overlapping lesion of larynx	0.000	0.997	0.003
C32.3 Laryngeal cartilage	0.000	0.997	0.003
C32.2 Subglottis	0.000	0.997	0.003
I02 Rheumatic chorea	0.003	0.997	0.000
I01 Rheumatic fever with heart involvement	0.003	0.997	0.000
I00 Rheumatic fever without mention of heart involvement	0.003	0.997	0.000
N21 Calculus of lower urinary tract	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.997	0.000
Q38.8 Other congenital malformations of pharynx	0.003	0.997	0.000
Q38.6 Other congenital malformations of mouth	0.003	0.997	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.003	0.997	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.003	0.997	0.000
Q38.3 Other congenital malformations of tongue	0.003	0.997	0.000
Q38.2 Macroglossia	0.003	0.997	0.000
Q38.1 Ankyloglossia	0.003	0.997	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.003	0.997	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
Q39.4 Oesophageal web	0.003	0.997	0.000
C32.1 Supraglottis	0.000	0.997	0.003
Q05.9 Spina bifida, unspecified	0.003	0.997	0.000
W19.4 Street and highway	0.000	0.997	0.003
I77.6 Arteritis, unspecified	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.997	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations