TreeWAS – Variant ID: rs3811345

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K55.2 Angiodysplasia of colon	0.000	0.970	0.030
H90.2 Conductive hearing loss, unspecified	0.030	0.970	0.000
H90 Conductive and sensorineural hearing loss	0.028	0.972	0.000
H90-H95 Other disorders of ear	0.025	0.975	0.000
H90.3 Sensorineural hearing loss, bilateral	0.025	0.975	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.024	0.976	0.000
H93 Other disorders of ear, not elsewhere classified	0.023	0.977	0.000
H93.1 Tinnitus	0.023	0.977	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.023	0.977	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.022	0.978	0.000
H90.5 Sensorineural hearing loss, unspecified	0.022	0.978	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.021	0.979	0.000
H92 Otalgia and effusion of ear	0.020	0.980	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.019	0.981	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.018	0.982	0.000
H91 Other hearing loss	0.018	0.982	0.000
H92.1 Otorrhoea	0.017	0.983	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.017	0.983	0.000
H93.8 Other specified disorders of ear	0.017	0.983	0.000
H93.3 Disorders of acoustic nerve	0.017	0.983	0.000
H93.2 Other abnormal auditory perceptions	0.017	0.983	0.000
H93.0 Degenerative and vascular disorders of ear	0.017	0.983	0.000
H91.1 Presbycusis	0.015	0.984	0.000
H92.2 Otorrhagia	0.015	0.985	0.000
H93.9 Disorder of ear, unspecified	0.015	0.985	0.000
S02.20 Fracture of nasal bones (closed)	0.015	0.985	0.000
S02.2 Fracture of nasal bones	0.014	0.986	0.000
H90.0 Conductive hearing loss, bilateral	0.014	0.986	0.000
S02 Fracture of skull and facial bones	0.014	0.986	0.000
H91.8 Other specified hearing loss	0.013	0.987	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.013	0.987	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.013	0.987	0.000
H91.2 Sudden idiopathic hearing loss	0.013	0.987	0.000
H91.0 Ototoxic hearing loss	0.013	0.987	0.000
Chapter VIII Diseases of the ear and mastoid process	0.013	0.987	0.000
H91.3 Deaf mutism, not elsewhere classified	0.013	0.987	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.013	0.987	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.013	0.987	0.000
H95.1 Other disorders following mastoidectomy	0.013	0.987	0.000
S06 Intracranial injury	0.012	0.988	0.000
H74.0 Tympanosclerosis	0.012	0.988	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.012	0.988	0.000
S02.4 Fracture of malar and maxillary bones	0.012	0.988	0.000
H65-H75 Diseases of middle ear and mastoid	0.012	0.988	0.000
H92.0 Otalgia	0.012	0.988	0.000
S06.2 Diffuse brain injury	0.012	0.988	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.012	0.988	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.012	0.988	0.000
S02.5 Fracture of tooth	0.012	0.988	0.000
S02.8 Fractures of other skull and facial bones	0.012	0.988	0.000
H74 Other disorders of middle ear and mastoid	0.012	0.988	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.012	0.988	0.000
S02.6 Fracture of mandible	0.011	0.989	0.000
S06.5 Traumatic subdural haemorrhage	0.011	0.989	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.011	0.989	0.000
S02.0 Fracture of vault of skull	0.011	0.989	0.000
S00-S09 Injuries to the head	0.011	0.989	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.011	0.989	0.000
K55 Vascular disorders of intestine	0.000	0.989	0.011
H72 Perforation of tympanic membrane	0.011	0.989	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.011	0.989	0.000
S02.3 Fracture of orbital floor	0.010	0.989	0.000
S02.21 Fracture of nasal bones (open)	0.010	0.989	0.000
S02.7 Multiple fractures involving skull and facial bones	0.010	0.989	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.010	0.990	0.000
H65 Nonsuppurative otitis media	0.010	0.990	0.000
S05 Injury of eye and orbit	0.010	0.990	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.010	0.990	0.000
H70 Mastoiditis and related conditions	0.010	0.990	0.000
S02.50 Fracture of tooth (closed)	0.010	0.990	0.000
H65.3 Chronic mucoid otitis media	0.010	0.990	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.010	0.990	0.000
S06.9 Intracranial injury, unspecified	0.010	0.990	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.010	0.990	0.000
S06.3 Focal brain injury	0.010	0.990	0.000
H73 Other disorders of tympanic membrane	0.009	0.991	0.000
S06.7 Intracranial injury with prolonged coma	0.009	0.991	0.000
S06.1 Traumatic cerebral oedema	0.009	0.991	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.991	0.009
S02.60 Fracture of mandible (closed)	0.009	0.991	0.000
H74.1 Adhesive middle ear disease	0.009	0.991	0.000
S02.1 Fracture of base of skull	0.009	0.991	0.000
S06.8 Other intracranial injuries	0.009	0.991	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.009	0.991	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.009	0.991	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.009	0.991	0.000
H68 Eustachian salpingitis and obstruction	0.009	0.991	0.000
H67 Otitis media in diseases classified elsewhere	0.009	0.991	0.000
S02.00 Fracture of vault of skull (closed)	0.009	0.991	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.009	0.991	0.000
S02.51 Fracture of tooth (open)	0.008	0.991	0.000
S02.81 Fractures of other skull and facial bones (open)	0.008	0.991	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.008	0.991	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.009	0.991	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.008	0.991	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.991	0.008
H70.9 Mastoiditis, unspecified	0.008	0.991	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.008	0.991	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.008	0.992	0.000
H72.8 Other perforations of tympanic membrane	0.008	0.992	0.000
H72.1 Attic perforation of tympanic membrane	0.008	0.992	0.000
S02.61 Fracture of mandible (open)	0.008	0.992	0.000
S06.4 Epidural haemorrhage	0.008	0.992	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.008	0.992	0.000
S05.1 Contusion of eyeball and orbital tissues	0.008	0.992	0.000
S02.01 Fracture of vault of skull (open)	0.008	0.992	0.000
S08 Traumatic amputation of part of head	0.008	0.992	0.000
S07 Crushing injury of head	0.008	0.992	0.000
S04 Injury of cranial nerves	0.008	0.992	0.000
H80-H83 Diseases of inner ear	0.008	0.992	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.008	0.992	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.008	0.992	0.000
H60-H62 Diseases of external ear	0.008	0.992	0.000
S02.31 Fracture of orbital floor (open)	0.008	0.992	0.000
S02.30 Fracture of orbital floor (closed)	0.008	0.992	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.008	0.992	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.008	0.992	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.008	0.992	0.000
H72.2 Other marginal perforations of tympanic membrane	0.008	0.992	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.007	0.992	0.000
H65.1 Other acute nonsuppurative otitis media	0.007	0.992	0.000
H65.0 Acute serous otitis media	0.007	0.992	0.000
S05.7 Avulsion of eye	0.007	0.992	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.007	0.992	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.007	0.992	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.007	0.992	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.007	0.992	0.000
H65.2 Chronic serous otitis media	0.007	0.992	0.000
H73.8 Other specified disorders of tympanic membrane	0.007	0.993	0.000
H70.8 Other mastoiditis and related conditions	0.007	0.993	0.000
H70.2 Petrositis	0.007	0.993	0.000
H70.1 Chronic mastoiditis	0.007	0.993	0.000
H70.0 Acute mastoiditis	0.007	0.993	0.000
S05.8 Other injuries of eye and orbit	0.007	0.993	0.000
S06.0 Concussion	0.007	0.993	0.000
F31.9 Bipolar affective disorder, unspecified	0.007	0.993	0.000
H66 Suppurative and unspecified otitis media	0.007	0.993	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.007	0.993	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.007	0.993	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.007	0.993	0.000
H73.1 Chronic myringitis	0.007	0.993	0.000
H73.0 Acute myringitis	0.007	0.993	0.000
S01 Open wound of head	0.007	0.993	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.007	0.993	0.000
F31 Bipolar affective disorder	0.007	0.993	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.007	0.993	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.007	0.993	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.007	0.993	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.007	0.993	0.000
H81 Disorders of vestibular function	0.007	0.993	0.000
S01.2 Open wound of nose	0.007	0.993	0.000
H74.4 Polyp of middle ear	0.007	0.993	0.000
I44.1 Atrioventricular block, second degree	0.000	0.993	0.007
K55.8 Other vascular disorders of intestine	0.000	0.993	0.007
S02.11 Fracture of base of skull (open)	0.007	0.993	0.000
S01.5 Open wound of lip and oral cavity	0.007	0.993	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.007	0.993	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.006	0.993	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.006	0.993	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.006	0.993	0.000
H68.1 Obstruction of Eustachian tube	0.006	0.993	0.000
H68.0 Eustachian salpingitis	0.006	0.993	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.006	0.993	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
S09 Other and unspecified injuries of head	0.007	0.993	0.000
H91.9 Hearing loss, unspecified	0.007	0.993	0.000
S05.9 Injury of eye and orbit, part unspecified	0.006	0.993	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.006	0.993	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.006	0.994	0.000
Q25 Congenital malformations of great arteries	0.006	0.994	0.000
H65.4 Other chronic nonsuppurative otitis media	0.006	0.994	0.000
S01.8 Open wound of other parts of head	0.006	0.994	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.006	0.994	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.006	0.994	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.006	0.994	0.000
S04.9 Injury of unspecified cranial nerve	0.006	0.994	0.000
S04.8 Injury of other cranial nerves	0.006	0.994	0.000
S04.7 Injury of accessory nerve	0.006	0.994	0.000
S04.6 Injury of acoustic nerve	0.006	0.994	0.000
S04.5 Injury of facial nerve	0.006	0.994	0.000
S04.4 Injury of abducent nerve	0.006	0.994	0.000
S04.3 Injury of trigeminal nerve	0.006	0.994	0.000
S04.2 Injury of trochlear nerve	0.006	0.994	0.000
S04.1 Injury of oculomotor nerve	0.006	0.994	0.000
S04.0 Injury of optic nerve and pathways	0.006	0.994	0.000
S07.9 Crushing injury of head, part unspecified	0.006	0.994	0.000
S07.8 Crushing injury of other parts of head	0.006	0.994	0.000
S07.1 Crushing injury of skull	0.006	0.994	0.000
S07.0 Crushing injury of face	0.006	0.994	0.000
S08.9 Traumatic amputation of unspecified part of head	0.006	0.994	0.000
S08.8 Traumatic amputation of other parts of head	0.006	0.994	0.000
S08.1 Traumatic amputation of ear	0.006	0.994	0.000
S08.0 Avulsion of scalp	0.006	0.994	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.006	0.994	0.000
Q21 Congenital malformations of cardiac septa	0.006	0.994	0.000
Q21.0 Ventricular septal defect	0.006	0.994	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.006	0.994	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.006	0.994	0.000
S03.4 Sprain and strain of jaw	0.006	0.994	0.000
S03.3 Dislocation of other and unspecified parts of head	0.006	0.994	0.000
S03.1 Dislocation of septal cartilage of nose	0.006	0.994	0.000
S03.0 Dislocation of jaw	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
H81.9 Disorder of vestibular function, unspecified	0.006	0.994	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
H81.2 Vestibular neuronitis	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
H81.0 Meniere's disease	0.006	0.994	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.006	0.994	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.994	0.006
F31.8 Other bipolar affective disorders	0.006	0.994	0.000
S03.2 Dislocation of tooth	0.005	0.994	0.000
Q25.4 Other congenital malformations of aorta	0.006	0.994	0.000
S06.01 Concussion (with open intracranial wound)	0.005	0.994	0.000
Q25.0 Patent ductus arteriosus	0.005	0.994	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.005	0.994	0.000
H66.0 Acute suppurative otitis media	0.005	0.994	0.000
H61 Other disorders of external ear	0.005	0.994	0.000
Q25.1 Coarctation of aorta	0.005	0.995	0.000
Q25.3 Stenosis of aorta	0.005	0.995	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.005	0.995	0.000
Q21.1 Atrial septal defect	0.005	0.995	0.000
H80 Otosclerosis	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
F31.7 Bipolar affective disorder, currently in remission	0.005	0.995	0.000
H81.8 Other disorders of vestibular function	0.005	0.995	0.000
H81.4 Vertigo of central origin	0.005	0.995	0.000
H81.3 Other peripheral vertigo	0.005	0.995	0.000
S02.10 Fracture of base of skull (closed)	0.005	0.995	0.000
T90 Sequelae of injuries of head	0.005	0.995	0.000
H66.4 Suppurative otitis media, unspecified	0.005	0.995	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.005	0.995	0.000
S09.7 Multiple injuries of head	0.005	0.995	0.000
S09.2 Traumatic rupture of ear drum	0.005	0.995	0.000
S09.1 Injury of muscle and tendon of head	0.005	0.995	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.005	0.995	0.000
S01.9 Open wound of head, part unspecified	0.005	0.995	0.000
S01.3 Open wound of ear	0.005	0.995	0.000
S09.8 Other specified injuries of head	0.005	0.995	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.005	0.995	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.005	0.995	0.000
H69.0 Patulous Eustachian tube	0.005	0.995	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.005	0.995	0.000
Q25.8 Other congenital malformations of great arteries	0.005	0.995	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.005	0.995	0.000
Q25.6 Stenosis of pulmonary artery	0.005	0.995	0.000
Q25.5 Atresia of pulmonary artery	0.005	0.995	0.000
Q25.2 Atresia of aorta	0.005	0.995	0.000
H61.0 Perichondritis of external ear	0.005	0.995	0.000
H60 Otitis externa	0.005	0.995	0.000
H61.9 Disorder of external ear, unspecified	0.005	0.995	0.000
H72.0 Central perforation of tympanic membrane	0.004	0.995	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.005	0.995	0.000
Q21.8 Other congenital malformations of cardiac septa	0.005	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
T90.8 Sequelae of other specified injuries of head	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.004	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.995	0.000
H83 Other diseases of inner ear	0.004	0.995	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H62.2 Otitis externa in mycoses	0.004	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.995	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.995	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
H69.8 Other specified disorders of Eustachian tube	0.004	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.996	0.004
T90.4 Sequelae of injury of eye and orbit	0.004	0.996	0.000
Q27 Other congenital malformations of peripheral vascular system	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.004	0.996	0.000
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
Q24.5 Malformation of coronary vessels	0.004	0.996	0.000
J45.0 Predominantly allergic asthma	0.000	0.996	0.004
T47.0 Histamine H(2)-receptor antagonists	0.004	0.996	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.996	0.000
S83.2 Tear of meniscus, current	0.000	0.996	0.004
H66.9 Otitis media, unspecified	0.004	0.996	0.000
H80.8 Other otosclerosis	0.004	0.996	0.000
H80.2 Cochlear otosclerosis	0.004	0.996	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.004	0.996	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.004	0.996	0.000
Q24.6 Congenital heart block	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
Q24.0 Dextrocardia	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
C34.9 Bronchus or lung, unspecified	0.004	0.996	0.000
H60.0 Abscess of external ear	0.004	0.996	0.000
Q43.0 Meckel's diverticulum	0.004	0.996	0.000
T90.3 Sequelae of injury of cranial nerves	0.004	0.996	0.000
T90.1 Sequelae of open wound of head	0.004	0.996	0.000
T90.0 Sequelae of superficial injury of head	0.004	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q80-Q89 Other congenital malformations	0.004	0.996	0.000
H61.8 Other specified disorders of external ear	0.004	0.996	0.000
H60.8 Other otitis externa	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H83.9 Disease of inner ear, unspecified	0.004	0.996	0.000
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.996	0.004
Q43 Other congenital malformations of intestine	0.004	0.996	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.004	0.996	0.000
S01.7 Multiple open wounds of head	0.004	0.996	0.000
T90.5 Sequelae of intracranial injury	0.004	0.996	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.003	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.996	0.000
S01.0 Open wound of scalp	0.004	0.996	0.000
T90.9 Sequelae of unspecified injury of head	0.004	0.996	0.000
L73.2 Hidradenitis suppurativa	0.004	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.003	0.996	0.000
H60.2 Malignant otitis externa	0.003	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.996	0.000
T47.7 Emetics	0.003	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.996	0.000
T47.5 Digestants	0.003	0.996	0.000
T47.4 Other laxatives	0.003	0.996	0.000
T47.3 Saline and osmotic laxatives	0.003	0.996	0.000
T47.2 Stimulant laxatives	0.003	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.003	0.996	0.000
T46.7 Peripheral vasodilators	0.003	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
H71 Cholesteatoma of middle ear	0.003	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.996	0.000
H61.1 Non-infective disorders of pinna	0.003	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.996	0.000
Q20.4 Double inlet ventricle	0.003	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.996	0.000
Q20.2 Double outlet left ventricle	0.003	0.996	0.000
Q20.1 Double outlet right ventricle	0.003	0.996	0.000
Q20.0 Common arterial trunk	0.003	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.996	0.000
Q26.1 Persistent left superior vena cava	0.003	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.996	0.000
H83.3 Noise effects on inner ear	0.003	0.996	0.000
H83.2 Labyrinthine dysfunction	0.003	0.996	0.000
H83.1 Labyrinthine fistula	0.003	0.996	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.004	0.996	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.003	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.003	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.003	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
H83.8 Other specified diseases of inner ear	0.003	0.996	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.996	0.000
I77.1 Stricture of artery	0.000	0.997	0.003
Q66 Congenital deformities of feet	0.003	0.997	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.003	0.997	0.000
L73 Other follicular disorders	0.003	0.997	0.000
T25 Burn and corrosion of ankle and foot	0.003	0.997	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.997	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q27.4 Congenital phlebectasia	0.003	0.997	0.000
Q27.2 Other congenital malformations of renal artery	0.003	0.997	0.000
Q27.1 Congenital renal artery stenosis	0.003	0.997	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.003	0.997	0.000
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
T21 Burn and corrosion of trunk	0.003	0.997	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.003	0.997	0.000
Q87.4 Marfan's syndrome	0.003	0.997	0.000
Q89 Other congenital malformations, not elsewhere classified	0.003	0.997	0.000
S09.9 Unspecified injury of head	0.003	0.997	0.000
L60.8 Other nail disorders	0.003	0.997	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.997	0.003
T91.1 Sequelae of fracture of spine	0.003	0.997	0.000
Q82 Other congenital malformations of skin	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
T46.1 Calcium-channel blockers	0.003	0.997	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.997	0.000
T02 Fractures involving multiple body regions	0.003	0.997	0.000
T36 Poisoning by systemic antibiotics	0.003	0.997	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.003	0.997	0.000
L73.9 Follicular disorder, unspecified	0.003	0.997	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.997	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.997	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.997	0.000
Q23.3 Congenital mitral insufficiency	0.003	0.997	0.000
Q23.2 Congenital mitral stenosis	0.003	0.997	0.000
Q66.8 Other congenital deformities of feet	0.003	0.997	0.000
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.003	0.997	0.000
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.001
Q23.0 Congenital stenosis of aortic valve	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
L73.8 Other specified follicular disorders	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.003	0.997	0.000
H60.3 Other infective otitis externa	0.003	0.997	0.000
L29.9 Pruritus, unspecified	0.000	0.997	0.003
K58 Irritable bowel syndrome	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
T21.3 Burn of third degree of trunk	0.003	0.997	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.003	0.997	0.000
Q84 Other congenital malformations of integument	0.003	0.997	0.000
Q81 Epidermolysis bullosa	0.003	0.997	0.000
Q80 Congenital ichthyosis	0.003	0.997	0.000
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.003	0.997	0.000
T25.2 Burn of second degree of ankle and foot	0.003	0.997	0.000
T45.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
S01.4 Open wound of cheek and temporomandibular area	0.002	0.997	0.001
K31.1 Adult hypertrophic pyloric stenosis	0.003	0.997	0.000
T21.0 Burn of unspecified degree of trunk	0.003	0.997	0.000
T56.8 Other metals	0.003	0.997	0.000
T98 Sequelae of other and unspecified effects of external causes	0.003	0.997	0.000
Q43.7 Persistent cloaca	0.003	0.997	0.000
Q43.6 Congenital fistula of rectum and anus	0.003	0.997	0.000
Q43.5 Ectopic anus	0.003	0.997	0.000
Q43.4 Duplication of intestine	0.003	0.997	0.000
Q43.2 Other congenital functional disorders of colon	0.003	0.997	0.000
Q43.1 Hirschsprung's disease	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
D23.1 Skin of eyelid, including canthus	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.997	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.997	0.000
Q73 Reduction defects of unspecified limb	0.003	0.997	0.000
Q72 Reduction defects of lower limb	0.003	0.997	0.000
Q71 Reduction defects of upper limb	0.003	0.997	0.000
Q70 Syndactyly	0.003	0.997	0.000
Q69 Polydactyly	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.997	0.000
Q83 Congenital malformations of breast	0.003	0.997	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.003	0.997	0.000
C67.3 Anterior wall of bladder	0.003	0.997	0.000
C34 Malignant neoplasm of bronchus and lung	0.003	0.997	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations