TreeWAS – Variant ID: rs381815

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.253	0.747	0.000
I10-I15 Hypertensive diseases	0.129	0.871	0.000
I15 Secondary hypertension	0.112	0.888	0.000
I15.1 Hypertension secondary to other renal disorders	0.093	0.906	0.000
I13 Hypertensive heart and renal disease	0.092	0.907	0.000
I15.0 Renovascular hypertension	0.092	0.908	0.000
I15.8 Other secondary hypertension	0.091	0.909	0.000
I12 Hypertensive renal disease	0.090	0.910	0.000
I12.9 Hypertensive renal disease without renal failure	0.081	0.919	0.000
I15.2 Hypertension secondary to endocrine disorders	0.081	0.919	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.066	0.933	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.066	0.933	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.066	0.933	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.066	0.933	0.000
I15.9 Seconday hypertension, unspecified	0.066	0.933	0.000
I11 Hypertensive heart disease	0.066	0.934	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.041	0.958	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.032	0.967	0.000
I27.0 Primary pulmonary hypertension	0.030	0.970	0.000
I27 Other pulmonary heart diseases	0.030	0.970	0.000
I27.2 Other secondary pulmonary hypertension	0.029	0.971	0.000
I51.7 Cardiomegaly	0.028	0.972	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.026	0.974	0.000
I27.8 Other specified pulmonary heart diseases	0.025	0.975	0.000
Chapter IX Diseases of the circulatory system	0.025	0.975	0.000
I31.9 Disease of pericardium, unspecified	0.024	0.976	0.000
I33.0 Acute and subacute infective endocarditis	0.024	0.976	0.000
I31 Other diseases of pericardium	0.023	0.977	0.000
I33 Acute and subacute endocarditis	0.023	0.977	0.000
I30-I52 Other forms of heart disease	0.022	0.978	0.000
I51 Complications and ill-defined descriptions of heart disease	0.022	0.978	0.000
I47 Paroxysmal tachycardia	0.022	0.978	0.000
I27.1 Kyphoscoliotic heart disease	0.022	0.978	0.000
I05-I09 Chronic rheumatic heart diseases	0.021	0.979	0.000
I45 Other conduction disorders	0.020	0.980	0.000
I31.0 Chronic adhesive pericarditis	0.020	0.980	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.980	0.020
I45.1 Other and unspecified right bundle-branch block	0.020	0.980	0.000
I47.0 Reentry ventricular arrhythmia	0.020	0.980	0.000
I28 Other diseases of pulmonary vessels	0.019	0.981	0.000
O03.9 Complete or unspecified, without complication	0.019	0.981	0.000
I45.5 Other specified heart block	0.019	0.981	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.019	0.981	0.000
I85.0 Oesophageal varices with bleeding	0.019	0.981	0.000
I51.4 Myocarditis, unspecified	0.019	0.981	0.000
I31.1 Chronic constrictive pericarditis	0.018	0.982	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.018	0.982	0.000
I45.3 Trifascicular block	0.018	0.982	0.000
I09 Other rheumatic heart diseases	0.017	0.983	0.000
I47.1 Supraventricular tachycardia	0.017	0.983	0.000
I31.8 Other specified diseases of pericardium	0.017	0.983	0.000
I31.2 Haemopericardium, not elsewhere classified	0.017	0.983	0.000
I33.9 Acute endocarditis, unspecified	0.017	0.983	0.000
I05 Rheumatic mitral valve diseases	0.017	0.983	0.000
I85 Oesophageal varices	0.017	0.983	0.000
I08 Multiple valve diseases	0.017	0.983	0.000
I00-I02 Acute rheumatic fever	0.016	0.984	0.000
I52 Other heart disorders in diseases classified elsewhere	0.016	0.984	0.000
I48 Atrial fibrillation and flutter	0.016	0.984	0.000
I41 Myocarditis in diseases classified elsewhere	0.016	0.984	0.000
I40 Acute myocarditis	0.016	0.984	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.016	0.984	0.000
I32 Pericarditis in diseases classified elsewhere	0.016	0.984	0.000
I07 Rheumatic tricuspid valve diseases	0.016	0.984	0.000
I05.2 Mitral stenosis with insufficiency	0.016	0.984	0.000
I51.5 Myocardial degeneration	0.016	0.984	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.016	0.984	0.000
I47.2 Ventricular tachycardia	0.016	0.984	0.000
I34 Nonrheumatic mitral valve disorders	0.016	0.984	0.000
I51.9 Heart disease, unspecified	0.016	0.984	0.000
I08.0 Disorders of both mitral and aortic valves	0.016	0.984	0.000
I30 Acute pericarditis	0.015	0.985	0.000
I85.9 Oesophageal varices without bleeding	0.015	0.985	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.015	0.985	0.000
I06 Rheumatic aortic valve diseases	0.015	0.985	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.015	0.985	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.015	0.985	0.000
I45.8 Other specified conduction disorders	0.015	0.985	0.000
I45.0 Right fascicular block	0.015	0.985	0.000
I09.9 Rheumatic heart disease, unspecified	0.015	0.985	0.000
I36 Nonrheumatic tricuspid valve disorders	0.014	0.986	0.000
I26 Pulmonary embolism	0.014	0.986	0.000
I08.8 Other multiple valve diseases	0.014	0.986	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.014	0.986	0.000
I28.1 Aneurysm of pulmonary artery	0.014	0.986	0.000
I27.9 Pulmonary heart disease, unspecified	0.014	0.986	0.000
C90.0 Multiple myeloma	0.000	0.986	0.014
I28.8 Other specified diseases of pulmonary vessels	0.013	0.987	0.000
I37 Pulmonary valve disorders	0.013	0.987	0.000
I45.4 Nonspecific intraventricular block	0.013	0.987	0.000
I05.1 Rheumatic mitral insufficiency	0.013	0.987	0.000
I09.8 Other specified rheumatic heart diseases	0.013	0.987	0.000
I09.2 Chronic rheumatic pericarditis	0.013	0.987	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.013	0.987	0.000
I09.0 Rheumatic myocarditis	0.013	0.987	0.000
I51.6 Cardiovascular disease, unspecified	0.012	0.987	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.012	0.988	0.000
I07.1 Tricuspid insufficiency	0.012	0.988	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.012	0.988	0.000
I05.8 Other mitral valve diseases	0.012	0.988	0.000
I34.1 Mitral (valve) prolapse	0.012	0.988	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.988	0.012
I51.3 Intracardiac thrombosis, not elsewhere classified	0.012	0.988	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.012	0.988	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.012	0.988	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.012	0.988	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.012	0.988	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.012	0.988	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.012	0.988	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.012	0.988	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.012	0.988	0.000
I40.9 Acute myocarditis, unspecified	0.012	0.988	0.000
I40.8 Other acute myocarditis	0.012	0.988	0.000
I40.1 Isolated myocarditis	0.012	0.988	0.000
I40.0 Infective myocarditis	0.012	0.988	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.012	0.988	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.012	0.988	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.012	0.988	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.012	0.988	0.000
I48.4 Atypical atrial flutter	0.012	0.988	0.000
I48.3 Typical atrial flutter	0.012	0.988	0.000
I48.2 Chronic atrial fibrillation	0.012	0.988	0.000
I48.1 Persistent atrial fibrillation	0.012	0.988	0.000
I48.0 Paroxysmal atrial fibrillation	0.012	0.988	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.012	0.988	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.012	0.988	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.012	0.988	0.000
I02 Rheumatic chorea	0.012	0.988	0.000
I01 Rheumatic fever with heart involvement	0.012	0.988	0.000
I07.9 Tricuspid valve disease, unspecified	0.012	0.988	0.000
I07.8 Other tricuspid valve diseases	0.012	0.988	0.000
I07.2 Tricuspid stenosis with insufficiency	0.012	0.988	0.000
I07.0 Tricuspid stenosis	0.012	0.988	0.000
I31.3 Pericardial effusion (noninflammatory)	0.012	0.988	0.000
I12.0 Hypertensive renal disease with renal failure	0.012	0.988	0.000
I45.9 Conduction disorder, unspecified	0.011	0.988	0.000
I30.8 Other forms of acute pericarditis	0.011	0.989	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.011	0.989	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.011	0.989	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.011	0.989	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.011	0.989	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.011	0.989	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
I30.1 Infective pericarditis	0.011	0.989	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.011	0.989	0.000
I06.8 Other rheumatic aortic valve diseases	0.011	0.989	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.011	0.989	0.000
I06.1 Rheumatic aortic insufficiency	0.011	0.989	0.000
I46 Cardiac arrest	0.011	0.989	0.000
I88 Nonspecific lymphadenitis	0.011	0.989	0.000
I34.0 Mitral (valve) insufficiency	0.011	0.989	0.000
I06.0 Rheumatic aortic stenosis	0.011	0.989	0.000
I42 Cardiomyopathy	0.011	0.989	0.000
I30.9 Acute pericarditis, unspecified	0.011	0.989	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.010	0.989	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.010	0.989	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.010	0.989	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.010	0.989	0.000
I88.9 Nonspecific lymphadenitis, unspecified	0.010	0.990	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.010	0.990	0.000
I00 Rheumatic fever without mention of heart involvement	0.010	0.990	0.000
I08.9 Multiple valve disease, unspecified	0.010	0.990	0.000
I72.0 Aneurysm of carotid artery	0.010	0.990	0.000
I81 Portal vein thrombosis	0.010	0.990	0.000
I44 Atrioventricular and left bundle-branch block	0.010	0.990	0.000
I45.2 Bifascicular block	0.010	0.990	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.010	0.990	0.000
I37.9 Pulmonary valve disorder, unspecified	0.009	0.990	0.000
I37.8 Other pulmonary valve disorders	0.009	0.990	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.009	0.990	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.010	0.990	0.000
I72 Other aneurysm	0.009	0.991	0.000
I51.0 Cardiac septal defect, acquired	0.009	0.991	0.000
I37.0 Pulmonary valve stenosis	0.009	0.991	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.991	0.009
I78 Diseases of capillaries	0.009	0.991	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.991	0.009
I05.9 Mitral valve disease, unspecified	0.009	0.991	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.991	0.009
G04.1 Tropical spastic paraplegia	0.000	0.991	0.009
G04.0 Acute disseminated encephalitis	0.000	0.991	0.009
S22.4 Multiple fractures of ribs	0.000	0.991	0.009
I45.6 Preexcitation syndrome	0.009	0.991	0.000
S22.50 Flail chest (closed)	0.000	0.991	0.009
S22.5 Flail chest	0.000	0.991	0.009
I01.9 Acute rheumatic heart disease, unspecified	0.009	0.991	0.000
I01.8 Other acute rheumatic heart disease	0.009	0.991	0.000
I01.2 Acute rheumatic myocarditis	0.009	0.991	0.000
I01.1 Acute rheumatic endocarditis	0.009	0.991	0.000
I01.0 Acute rheumatic pericarditis	0.009	0.991	0.000
I02.9 Rheumatic chorea without heart involvement	0.009	0.991	0.000
I02.0 Rheumatic chorea with heart involvement	0.009	0.991	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.991	0.009
I86 Varicose veins of other sites	0.009	0.991	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.008	0.992	0.000
I46.9 Cardiac arrest, unspecified	0.008	0.992	0.000
I05.0 Mitral stenosis	0.008	0.992	0.000
H53.8 Other visual disturbances	0.000	0.992	0.008
I46.1 Sudden cardiac death, so described	0.008	0.992	0.000
I88.1 Chronic lymphadenitis, except mesenteric	0.008	0.992	0.000
I88.0 Nonspecific mesenteric lymphadenitis	0.008	0.992	0.000
I88.8 Other nonspecific lymphadenitis	0.008	0.992	0.000
I44.3 Other and unspecified atrioventricular block	0.008	0.992	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.992	0.008
I42.0 Dilated cardiomyopathy	0.008	0.992	0.000
I42.5 Other restrictive cardiomyopathy	0.008	0.992	0.000
I42.4 Endocardial fibroelastosis	0.008	0.992	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.008	0.992	0.000
I87 Other disorders of veins	0.008	0.992	0.000
I42.6 Alcoholic cardiomyopathy	0.008	0.992	0.000
I86.2 Pelvic varices	0.008	0.992	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.008	0.992	0.000
I72.4 Aneurysm of artery of lower extremity	0.008	0.992	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.992	0.008
I78.1 Naevus, nonneoplastic	0.008	0.992	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.992	0.008
I44.4 Left anterior fascicular block	0.008	0.992	0.000
I42.2 Other hypertrophic cardiomyopathy	0.008	0.992	0.000
I51.8 Other ill-defined heart diseases	0.008	0.992	0.000
I42.9 Cardiomyopathy, unspecified	0.008	0.992	0.000
I72.2 Aneurysm of renal artery	0.008	0.992	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.992	0.008
I78.9 Disease of capillaries, unspecified	0.008	0.992	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.008	0.992	0.000
I78.8 Other diseases of capillaries	0.008	0.992	0.000
S22.3 Fracture of rib	0.000	0.992	0.008
I44.5 Left posterior fascicular block	0.007	0.993	0.000
S22.2 Fracture of sternum	0.000	0.993	0.007
I44.6 Other and unspecified fascicular block	0.007	0.993	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.993	0.007
I37.1 Pulmonary valve insufficiency	0.007	0.993	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.007	0.993	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.007	0.993	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.007	0.993	0.000
I72.1 Aneurysm of artery of upper extremity	0.007	0.993	0.000
I70 Atherosclerosis	0.007	0.993	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.993	0.007
I72.9 Aneurysm of unspecified site	0.007	0.993	0.000
S02.20 Fracture of nasal bones (closed)	0.007	0.993	0.000
C90.3 Solitary plasmacytoma	0.000	0.993	0.007
G00 Bacterial meningitis, not elsewhere classified	0.000	0.993	0.007
I87.9 Disorder of vein, unspecified	0.007	0.993	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.993	0.007
S22.8 Fracture of other parts of bony thorax	0.000	0.993	0.007
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.007	0.993	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.993	0.007
I44.0 Atrioventricular block, first degree	0.007	0.993	0.000
I87.1 Compression of vein	0.007	0.993	0.000
S22.51 Flail chest (open)	0.000	0.993	0.006
C90.1 Plasma cell leukaemia	0.000	0.993	0.006
I86.0 Sublingual varices	0.006	0.993	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.006	0.994	0.000
S22.30 Fracture of rib (closed)	0.000	0.994	0.006
H54.9 Unspecified visual impairment (binocular)	0.000	0.994	0.006
I86.3 Vulval varices	0.006	0.994	0.000
I86.4 Gastric varices	0.006	0.994	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.000	0.994	0.006
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.994	0.006
S22.20 Fracture of sternum (closed)	0.000	0.994	0.006
G00.1 Pneumococcal meningitis	0.000	0.994	0.006
I42.1 Obstructive hypertrophic cardiomyopathy	0.006	0.994	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.006	0.994	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.994	0.006
I87.0 Postphlebitic syndrome	0.006	0.994	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.000	0.994	0.006
Q61.0 Congenital single renal cyst	0.006	0.994	0.000
I44.7 Left bundle-branch block, unspecified	0.006	0.994	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.000	0.994	0.006
S22.01 Fracture of thoracic vertebra (open)	0.000	0.994	0.006
G03 Meningitis due to other and unspecified causes	0.000	0.994	0.006
G09 Sequelae of inflammatory diseases of central nervous system	0.000	0.994	0.006
I71 Aortic aneurysm and dissection	0.006	0.994	0.000
I42.8 Other cardiomyopathies	0.006	0.994	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.000	0.994	0.006
I44.2 Atrioventricular block, complete	0.006	0.994	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
S22.31 Fracture of rib (open)	0.000	0.994	0.006
I86.8 Varicose veins of other specified sites	0.006	0.994	0.000
I70.9 Generalised and unspecified atherosclerosis	0.006	0.994	0.000
S22.21 Fracture of sternum (open)	0.000	0.994	0.005
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.994	0.005
G00.9 Bacterial meningitis, unspecified	0.000	0.994	0.005
I50 Heart failure	0.005	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.005	0.995	0.000
I79.1 Aortitis in diseases classified elsewhere	0.005	0.995	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.005	0.995	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.995	0.005
O03 Spontaneous abortion	0.005	0.995	0.000
I72.8 Aneurysm of other specified arteries	0.005	0.995	0.000
S02.2 Fracture of nasal bones	0.005	0.995	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.005	0.995	0.000
G00.8 Other bacterial meningitis	0.000	0.995	0.005
G00.3 Staphylococcal meningitis	0.000	0.995	0.005
G00.2 Streptococcal meningitis	0.000	0.995	0.005
G00.0 Haemophilus meningitis	0.000	0.995	0.005
I44.1 Atrioventricular block, second degree	0.005	0.995	0.000
G93.3 Postviral fatigue syndrome	0.005	0.995	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.995	0.005
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.995	0.005
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.995	0.005
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.995	0.005
I70.8 Atherosclerosis of other arteries	0.005	0.995	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.995	0.005
G02.0 Meningitis in viral diseases classified elsewhere	0.000	0.995	0.005
I87.8 Other specified disorders of veins	0.005	0.995	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.005	0.995	0.000
I72.3 Aneurysm of iliac artery	0.005	0.995	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.005	0.995	0.000
I82 Other venous embolism and thrombosis	0.005	0.995	0.000
I38 Endocarditis, valve unspecified	0.005	0.995	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.000	0.995	0.005
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.000	0.995	0.005
T79.7 Traumatic subcutaneous emphysema	0.000	0.995	0.005
Z73.9 Problem related to life-management difficulty, unspecified	0.005	0.995	0.000
H53.1 Subjective visual disturbances	0.000	0.995	0.005
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.005	0.995	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.000	0.995	0.004
G02.1 Meningitis in mycoses	0.000	0.995	0.004
S02.21 Fracture of nasal bones (open)	0.005	0.995	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.995	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.995	0.005
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.995	0.005
I86.1 Scrotal varices	0.004	0.995	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.995	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.995	0.000
G03.9 Meningitis, unspecified	0.000	0.995	0.004
I70.0 Atherosclerosis of aorta	0.004	0.995	0.000
G03.8 Meningitis due to other specified causes	0.000	0.996	0.004
G03.2 Benign recurrent meningitis [Mollaret]	0.000	0.996	0.004
G03.1 Chronic meningitis	0.000	0.996	0.004
G03.0 Nonpyogenic meningitis	0.000	0.996	0.004
I71.8 Aortic aneurysm of unspecified site, ruptured	0.004	0.996	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.004	0.996	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.004	0.996	0.000
N97.9 Female infertility, unspecified	0.004	0.996	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.000	0.996	0.004
N97.1 Female infertility of tubal origin	0.004	0.996	0.000
H53 Visual disturbances	0.000	0.996	0.004
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
I89.0 Lymphoedema, not elsewhere classified	0.004	0.996	0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.996	0.000
O03.3 Incomplete, with other and unspecified complications	0.004	0.996	0.000
Q61 Cystic kidney disease	0.004	0.996	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.996	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.004	0.996	0.000
O03.7 Complete or unspecified, complicated by embolism	0.004	0.996	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.004	0.996	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.004	0.996	0.000
O03.2 Incomplete, complicated by embolism	0.004	0.996	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.004	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
N10 Acute tubulo-interstitial nephritis	0.004	0.996	0.000
N97 Female infertility	0.004	0.996	0.000
H53.4 Visual field defects	0.000	0.996	0.004
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.996	0.004
T79.8 Other early complications of trauma	0.000	0.996	0.004
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.000	0.996	0.004
N97.4 Female infertility associated with male factors	0.004	0.996	0.000
T79.9 Unspecified early complication of trauma	0.000	0.996	0.004
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.996	0.004
T79.1 Fat embolism (traumatic)	0.000	0.996	0.004
T79.0 Air embolism (traumatic)	0.000	0.996	0.004
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.004	0.996	0.000
I82.1 Thrombophlebitis migrans	0.004	0.996	0.000
I82.0 Budd-Chiari syndrome	0.004	0.996	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.996	0.004
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.004	0.996	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.004	0.996	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.003	0.996	0.000
S27.2 Traumatic heamopneumothorax	0.000	0.996	0.004
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.004	0.996	0.000
T79.5 Traumatic anuria	0.000	0.996	0.003
G90.0 Idiopathic peripheral autonomic neuropathy	0.004	0.996	0.000
N97.0 Female infertility associated with anovulation	0.003	0.996	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.003	0.996	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.003	0.997	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
T79.4 Traumatic shock	0.000	0.997	0.003
H53.6 Night blindness	0.000	0.997	0.003
H53.5 Colour vision deficiencies	0.000	0.997	0.003
H53.3 Other disorders of binocular vision	0.000	0.997	0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.003	0.997	0.000
I50.9 Heart failure, unspecified	0.003	0.997	0.000
K22.9 Disease of oesophagus, unspecified	0.003	0.997	0.000
Q61.8 Other cystic kidney diseases	0.003	0.997	0.000
Q61.4 Renal dysplasia	0.003	0.997	0.000
Q61.1 Polycystic kidney, infantile type	0.003	0.997	0.000
S02.8 Fractures of other skull and facial bones	0.003	0.997	0.000
G06.2 Extradural and subdural abscess, unspecified	0.000	0.997	0.003
G93.2 Benign intracranial hypertension	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.003	0.997	0.000
N97.3 Female infertility of cervical origin	0.003	0.997	0.000
N97.2 Female infertility of uterine origin	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.000
I97.1 Other functional disturbances following cardiac surgery	0.003	0.997	0.000
I97.0 Postcardiotomy syndrome	0.003	0.997	0.000
I82.3 Embolism and thrombosis of renal vein	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.003	0.997	0.000
N97.8 Female infertility of other origin	0.003	0.997	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.003	0.997	0.000
G06.0 Intracranial abscess and granuloma	0.000	0.997	0.003
I97.9 Postprocedural disorder of circulatory system, unspecified	0.003	0.997	0.000
Q61.5 Medullary cystic kidney	0.003	0.997	0.000
G90.2 Horner's syndrome	0.003	0.997	0.000
I82.2 Embolism and thrombosis of vena cava	0.003	0.997	0.000
T92 Sequelae of injuries of upper limb	0.000	0.997	0.003
G06.1 Intraspinal abscess and granuloma	0.000	0.997	0.003
G90 Disorders of autonomic nervous system	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.997	0.003
I98 Other disorders of circulatory system in diseases classified elsewhere	0.003	0.997	0.000
S20-S29 Injuries to the thorax	0.000	0.997	0.003
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.997	0.003
S02.9 Fracture of skull and facial bones, part unspecified	0.003	0.997	0.000
G93 Other disorders of brain	0.003	0.997	0.000
H54 Blindness and low vision	0.000	0.997	0.003
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.003	0.997	0.000
H53-H54 Visual disturbances and blindness	0.000	0.997	0.003
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
G93.0 Cerebral cysts	0.003	0.997	0.000
H53.0 Amblyopia ex anopsia	0.000	0.997	0.003
I71.0 Dissection of aorta [any part]	0.003	0.997	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.003	0.997	0.000
I83 Varicose veins of lower extremities	0.003	0.997	0.000
S02.81 Fractures of other skull and facial bones (open)	0.003	0.997	0.000
S27.3 Other injuries of lung	0.000	0.997	0.003
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.003	0.997	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.003	0.997	0.000
S02.6 Fracture of mandible	0.003	0.997	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.997	0.003
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.997	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.997	0.003
I82.8 Embolism and thrombosis of other specified veins	0.002	0.997	0.000
S02.30 Fracture of orbital floor (closed)	0.003	0.997	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.997	0.000
G81.9 Hemiplegia, unspecified	0.000	0.997	0.003
I71.3 Abdominal aortic aneurysm, ruptured	0.002	0.997	0.000
S02.0 Fracture of vault of skull	0.002	0.997	0.000
H54.5 Low vision, one eye	0.000	0.997	0.002
T92.0 Sequelae of open wound of upper limb	0.000	0.997	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.998	0.002
I89.1 Lymphangitis	0.002	0.998	0.001
G90.8 Other disorders of autonomic nervous system	0.002	0.998	0.000
G90.4 Autonomic dysreflexia	0.002	0.998	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.998	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.998	0.002
S27.6 Injury of pleura	0.000	0.998	0.002
S27.5 Injury of thoracic trachea	0.000	0.998	0.002
S27.4 Injury of bronchus	0.000	0.998	0.002
I50.1 Left ventricular failure	0.002	0.998	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.002	0.998	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
I98.0 Cardiovascular syphilis	0.002	0.998	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.998	0.002
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.998	0.002
S26 Injury of heart	0.000	0.998	0.002
S25 Injury of blood vessels of thorax	0.000	0.998	0.002
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.998	0.002
E28.2 Polycystic ovarian syndrome	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
G93.7 Reye's syndrome	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.000	0.998	0.002
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
S20.3 Other superficial injuries of front wall of thorax	0.000	0.998	0.002
I73 Other peripheral vascular diseases	0.002	0.998	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.998	0.002
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
M75.0 Adhesive capsulitis of shoulder	0.000	0.998	0.002
L43.9 Lichen planus, unspecified	0.000	0.998	0.002
S29 Other and unspecified injuries of thorax	0.000	0.998	0.002
S24 Injury of nerves and spinal cord at thorax level	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.002	0.998	0.000
T79-T79 Certain early complications of trauma	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
N80.8 Other endometriosis	0.000	0.998	0.002
G90.3 Multisystem degeneration	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.002	0.998	0.000
S20 Superficial injury of thorax	0.000	0.998	0.002
S02.01 Fracture of vault of skull (open)	0.002	0.998	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.002	0.998	0.001
S02.5 Fracture of tooth	0.002	0.998	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.998	0.002
H54.4 Blindness, one eye	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations