TreeWAS – Variant ID: rs3819715

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	1.000
E10.9 Without complications	0.000	1.000
E10.3 With ophthalmic complications	0.000	1.000
K90.0 Coeliac disease	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	1.000
E10-E14 Diabetes mellitus	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	1.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999
E00-E07 Disorders of thyroid gland	0.001	0.999
E03 Other hypothyroidism	0.001	0.999
M05 Seropositive rheumatoid arthritis	0.001	0.999
M06 Other rheumatoid arthritis	0.002	0.998
M05-M14 Inflammatory polyarthropathies	0.002	0.998
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.003	0.997
Chapter IV Endocrine, nutritional and metabolic diseases	0.004	0.996
E10.4 With neurological complications	0.015	0.985
E10.1 With ketoacidosis	0.016	0.984
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.017	0.983
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.018	0.982
E11 Non-insulin-dependent diabetes mellitus	0.019	0.981
E05.9 Thyrotoxicosis, unspecified	0.019	0.981
E05.0 Thyrotoxicosis with diffuse goitre	0.026	0.974
E11.3 With ophthalmic complications	0.030	0.970
E10.5 With peripheral circulatory complications	0.032	0.968
E14 Unspecified diabetes mellitus	0.051	0.949
E10.2 With renal complications	0.051	0.949
H36.0 Diabetic retinopathy	0.052	0.948
E10.8 With unspecified complications	0.060	0.940
E10.0 With coma	0.081	0.919
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.101	0.899
E10.6 With other specified complications	0.113	0.887
M06.3 Rheumatoid nodule	0.122	0.878
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.126	0.874
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.127	0.873
M07 Psoriatic and enteropathic arthropathies	0.150	0.850
E14.3 With ophthalmic complications	0.150	0.850
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.156	0.844
E02 Subclinical iodine-deficiency hypothyroidism	0.164	0.836
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.173	0.827
E11.9 Without complications	0.173	0.827
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.195	0.805
E11.8 With unspecified complications	0.202	0.798
E11.1 With ketoacidosis	0.208	0.792
M06.98 Rheumatoid arthritis, unspecified (Other)	0.209	0.791
E16 Other disorders of pancreatic internal secretion	0.213	0.787
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.214	0.786
E14.8 With unspecified complications	0.214	0.786
E14.1 With ketoacidosis	0.231	0.769
M05.8 Other seropositive rheumatoid arthritis	0.231	0.768
E14.4 With neurological complications	0.242	0.758
M06.34 Rheumatoid nodule (Hand)	0.244	0.756
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.255	0.745
M07.3 Other psoriatic arthropathies	0.255	0.745
E50-E64 Other nutritional deficiencies	0.259	0.741
E11.2 With renal complications	0.266	0.734
M13 Other arthritis	0.267	0.733
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.268	0.732
M12 Other specific arthropathies	0.270	0.730
E16.2 Hypoglycaemia, unspecified	0.272	0.728
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.273	0.727
M05.2 Rheumatoid vasculitis	0.282	0.717
E10.7 With multiple complications	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.283	0.717
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.283	0.717
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.283	0.717
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.283	0.717
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.283	0.717
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.284	0.716
E00 Congenital iodine-deficiency syndrome	0.284	0.716
E03.5 Myxoedema coma	0.284	0.716
E03.4 Atrophy of thyroid (acquired)	0.284	0.716
E03.3 Postinfectious hypothyroidism	0.284	0.716
E03.0 Congenital hypothyroidism with diffuse goitre	0.284	0.716
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.284	0.716
M05.1 Rheumatoid lung disease	0.284	0.716
M05.0 Felty's syndrome	0.284	0.716
M06.2 Rheumatoid bursitis	0.284	0.716
M06.1 Adult-onset Still's disease	0.284	0.716
M09 Juvenile arthritis in diseases classified elsewhere	0.285	0.715
M08 Juvenile arthritis	0.285	0.715
E05.5 Thyroid crisis or storm	0.285	0.715
E05.4 Thyrotoxicosis factitia	0.285	0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.285	0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.285	0.715
E11.7 With multiple complications	0.296	0.703
E14.5 With peripheral circulatory complications	0.297	0.703
E11.4 With neurological complications	0.298	0.702
E05.8 Other thyrotoxicosis	0.302	0.698
M06.32 Rheumatoid nodule (Upper arm)	0.316	0.684
E14.7 With multiple complications	0.319	0.681
E14.6 With other specified complications	0.319	0.681
E14.0 With coma	0.319	0.681
E14.2 Withrenal complications	0.333	0.666
M35.3 Polymyalgia rheumatica	0.339	0.661
M11 Other crystal arthropathies	0.339	0.661
M06.37 Rheumatoid nodule (Ankle and foot)	0.345	0.655
M06.4 Inflammatory polyarthropathy	0.347	0.653
E03.1 Congenital hypothyroidism without goitre	0.348	0.652
M35 Other systemic involvement of connective tissue	0.349	0.651
M13.0 Polyarthritis, unspecified	0.351	0.649
M35.0 Sicca syndrome [Sjogren]	0.352	0.648
M06.8 Other specified rheumatoid arthritis	0.368	0.632
M06.39 Rheumatoid nodule (Site unspecified)	0.370	0.630
M06.38 Rheumatoid nodule (Other)	0.370	0.630
M06.36 Rheumatoid nodule (Lower leg)	0.370	0.630
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.370	0.630
M06.33 Rheumatoid nodule (Forearm)	0.370	0.630
M06.31 Rheumatoid nodule (Shoulder region)	0.370	0.630
M06.30 Rheumatoid nodule (Multiple sites)	0.370	0.630
E16.0 Drug-induced hypoglycaemia without coma	0.372	0.628
E15 Nondiabetic hypoglycaemic coma	0.373	0.627
M07.39 Other psoriatic arthropathies (Site unspecified)	0.376	0.624
E61 Deficiency of other nutrient elements	0.379	0.621
M14 Arthropathies in other diseases classified elsewhere	0.381	0.619
M07.6 Other enteropathic arthropathies	0.390	0.610
M07.5 Arthropathy in ulcerative colitis	0.390	0.610
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.390	0.610
M07.2 Psoriatic spondylitis	0.390	0.610
M07.1 Arthritis mutilans	0.390	0.610
M07.0 Distal interphalangeal psoriatic arthropathy	0.390	0.610
E14.9 Without complications	0.396	0.604
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.396	0.604
E51 Thiamine deficiency	0.413	0.587
M13.00 Polyarthritis, unspecified (Multiple sites)	0.415	0.585
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.423	0.577
M35.1 Other overlap syndromes	0.424	0.576
M07.30 Other psoriatic arthropathies (Multiple sites)	0.425	0.575
M13.1 Monoarthritis, not elsewhere classified	0.430	0.570
E11.0 With coma	0.435	0.565
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.435	0.565
E16.9 Disorder of pancreatic internal secretion, unspecified	0.436	0.564
E16.8 Other specified disorders of pancreatic internal secretion	0.436	0.564
E16.4 Abnormal secretion of gastrin	0.436	0.564
E16.3 Increased secretion of glucagon	0.436	0.564
M13.8 Other specified arthritis	0.436	0.564
M07.36 Other psoriatic arthropathies (Lower leg)	0.444	0.556
M07.34 Other psoriatic arthropathies (Hand)	0.447	0.553
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.449	0.551
M05.88 Other seropositive rheumatoid arthritis (Other)	0.449	0.551
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.449	0.551
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.449	0.551
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.449	0.551
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.449	0.551
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.449	0.551
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.449	0.551
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.449	0.551
E65-E68 Obesity and other hyperalimentation	0.453	0.547
E40-E46 Malnutrition	0.454	0.546
M35.7 Hypermobility syndrome	0.459	0.541
M12.3 Palindromic rheumatism	0.462	0.538
E11.5 With peripheral circulatory complications	0.463	0.537
M07.38 Other psoriatic arthropathies (Other)	0.466	0.534
M07.33 Other psoriatic arthropathies (Forearm)	0.466	0.534
M07.32 Other psoriatic arthropathies (Upper arm)	0.466	0.534
M07.31 Other psoriatic arthropathies (Shoulder region)	0.466	0.534
E64 Sequelae of malnutrition and other nutritional deficiencies	0.468	0.532
E63 Other nutritional deficiencies	0.468	0.532
E50 Vitamin A deficiency	0.468	0.532
E60 Dietary zinc deficiency	0.468	0.532
E59 Dietary selenium deficiency	0.468	0.532
E52 Niacin deficiency [pellagra]	0.468	0.532
E13 Other specified diabetes mellitus	0.471	0.528
M11.9 Crystal arthropathy, unspecified	0.474	0.525
M12.8 Other specific arthropathies, not elsewhere classified	0.477	0.523
M12.5 Traumatic arthropathy	0.477	0.523
M12.4 Intermittent hydrarthrosis	0.477	0.523
M12.1 Kaschin-Beck disease	0.477	0.523
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.477	0.523
M12.2 Villonodular synovitis (pigmented)	0.477	0.523
E58 Dietary calcium deficiency	0.480	0.520
M05.29 Rheumatoid vasculitis (Site unspecified)	0.484	0.516
M05.28 Rheumatoid vasculitis (Other)	0.485	0.514
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.485	0.514
M05.26 Rheumatoid vasculitis (Lower leg)	0.485	0.514
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.485	0.514
M05.24 Rheumatoid vasculitis (Hand)	0.485	0.514
M05.23 Rheumatoid vasculitis (Forearm)	0.485	0.514
M05.22 Rheumatoid vasculitis (Upper arm)	0.485	0.514
M05.21 Rheumatoid vasculitis (Shoulder region)	0.485	0.514
M05.20 Rheumatoid vasculitis (Multiple sites)	0.485	0.514
E12.9 Without complications	0.486	0.514
E12.8 With unspecified complications	0.486	0.514
E12.7 With multiple complications	0.486	0.514
E12.6 With other specified complications	0.486	0.514
E12.5 With peripheral circulatory complications	0.486	0.514
E12.4 With neurological complications	0.486	0.514
E12.3 With ophthalmic complications	0.486	0.514
E12.2 With renal complications	0.486	0.514
E12.1 With ketoacidosis	0.486	0.514
E12.0 With coma	0.486	0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.486	0.514
E56 Other vitamin deficiencies	0.486	0.513
M05.09 Felty's syndrome (Site unspecified)	0.487	0.513
M05.08 Felty's syndrome (Other)	0.487	0.513
M05.07 Felty's syndrome (Ankle and foot)	0.487	0.513
M05.06 Felty's syndrome (Lower leg)	0.487	0.513
M05.05 Felty's syndrome (Pelvic region and thigh)	0.487	0.513
M05.04 Felty's syndrome (Hand)	0.487	0.513
M05.03 Felty's syndrome (Forearm)	0.487	0.513
M05.02 Felty's syndrome (Upper arm)	0.487	0.513
M05.01 Felty's syndrome (Shoulder region)	0.487	0.513
M05.00 Felty's syndrome (Multiple sites)	0.487	0.513
M05.19 Rheumatoid lung disease (Site unspecified)	0.487	0.513
M05.18 Rheumatoid lung disease (Other)	0.487	0.513
M05.17 Rheumatoid lung disease (Ankle and foot)	0.487	0.513
M05.16 Rheumatoid lung disease (Lower leg)	0.487	0.513
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.487	0.513
M05.14 Rheumatoid lung disease (Hand)	0.487	0.513
M05.13 Rheumatoid lung disease (Forearm)	0.487	0.513
M05.12 Rheumatoid lung disease (Upper arm)	0.487	0.513
M05.11 Rheumatoid lung disease (Shoulder region)	0.487	0.513
M05.10 Rheumatoid lung disease (Multiple sites)	0.487	0.513
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.487	0.513
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.487	0.513
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.487	0.513
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.487	0.513
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.487	0.513
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.487	0.513
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.487	0.513
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.487	0.513
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.487	0.513
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.487	0.513
M06.19 Adult-onset Still's disease (Site unspecified)	0.487	0.513
M06.18 Adult-onset Still's disease (Other)	0.487	0.513
M06.17 Adult-onset Still's disease (Ankle and foot)	0.487	0.513
M06.16 Adult-onset Still's disease (Lower leg)	0.487	0.513
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.487	0.513
M06.14 Adult-onset Still's disease (Hand)	0.487	0.513
M06.13 Adult-onset Still's disease (Forearm)	0.487	0.513
M06.12 Adult-onset Still's disease (Upper arm)	0.487	0.513
M06.11 Adult-onset Still's disease (Shoulder region)	0.487	0.513
M06.10 Adult-onset Still's disease (Multiple sites)	0.487	0.513
M06.29 Rheumatoid bursitis (Site unspecified)	0.487	0.513
M06.28 Rheumatoid bursitis (Other)	0.487	0.513
M06.27 Rheumatoid bursitis (Ankle and foot)	0.487	0.513
M06.26 Rheumatoid bursitis (Lower leg)	0.487	0.513
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.487	0.513
M06.24 Rheumatoid bursitis (Hand)	0.487	0.513
M06.23 Rheumatoid bursitis (Forearm)	0.487	0.513
M06.22 Rheumatoid bursitis (Upper arm)	0.487	0.513
M06.21 Rheumatoid bursitis (Shoulder region)	0.487	0.513
M06.20 Rheumatoid bursitis (Multiple sites)	0.487	0.513
M08.9 Juvenile arthritis, unspecified	0.487	0.513
M08.8 Other juvenile arthritis	0.487	0.513
M08.4 Pauciarticular juvenile arthritis	0.487	0.513
M08.3 Juvenile polyarthritis (seronegative)	0.487	0.513
M08.2 Juvenile arthritis with systemic onset	0.487	0.513
M08.1 Juvenile ankylosing spondylitis	0.487	0.513
M08.0 Juvenile rheumatoid arthritis	0.487	0.513
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.487	0.513
M09.2 Juvenile arthritis in ulcerative colitis	0.487	0.513
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.487	0.513
M09.0 Juvenile arthritis in psoriasis	0.487	0.513
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.491	0.509
M10 Gout	0.499	0.501
E61.2 Magnesium deficiency	0.500	0.500
E06 Thyroiditis	0.503	0.497
E54 Ascorbic acid deficiency	0.505	0.495
E61.1 Iron deficiency	0.505	0.495
E53 Deficiency of other B group vitamins	0.513	0.487
M13.09 Polyarthritis, unspecified (Site unspecified)	0.513	0.487
E55 Vitamin D deficiency	0.523	0.477
E51.2 Wernicke's encephalopathy	0.524	0.476
M11.1 Familial chondrocalcinosis	0.526	0.474
M11.0 Hydroxyapatite deposition disease	0.526	0.474
M06.48 Inflammatory polyarthropathy (Other)	0.531	0.468
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.531	0.468
M06.46 Inflammatory polyarthropathy (Lower leg)	0.531	0.468
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.531	0.468
M06.44 Inflammatory polyarthropathy (Hand)	0.531	0.468
M06.43 Inflammatory polyarthropathy (Forearm)	0.531	0.468
M06.42 Inflammatory polyarthropathy (Upper arm)	0.531	0.468
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.531	0.468
M35.9 Systemic involvement of connective tissue, unspecified	0.533	0.467
M35.6 Relapsing panniculitis [Weber-Christian]	0.533	0.467
M35.5 Multifocal fibrosclerosis	0.533	0.467
M35.4 Diffuse (eosinophilic) fasciitis	0.533	0.467
M13.08 Polyarthritis, unspecified (Other)	0.534	0.466
M13.07 Polyarthritis, unspecified (Ankle and foot)	0.534	0.466
M13.06 Polyarthritis, unspecified (Lower leg)	0.534	0.466
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)	0.534	0.466
M13.03 Polyarthritis, unspecified (Forearm)	0.534	0.466
M13.02 Polyarthritis, unspecified (Upper arm)	0.534	0.466
M13.01 Polyarthritis, unspecified (Shoulder region)	0.534	0.466
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.542	0.458
E16.1 Other hypoglycaemia	0.544	0.456
E07 Other disorders of thyroid	0.544	0.456
M13.04 Polyarthritis, unspecified (Hand)	0.545	0.455
M06.88 Other specified rheumatoid arthritis (Other)	0.547	0.453
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.547	0.453
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.547	0.453
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.547	0.453
M06.84 Other specified rheumatoid arthritis (Hand)	0.547	0.453
M06.83 Other specified rheumatoid arthritis (Forearm)	0.547	0.453
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.547	0.453
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.547	0.453
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.547	0.453
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.547	0.453
M11.8 Other specified crystal arthropathies	0.547	0.452
E61.9 Deficiency of nutrient element, unspecified	0.555	0.445
E61.8 Deficiency of other specified nutrient elements	0.555	0.445
E61.7 Deficiency of multiple nutrient elements	0.555	0.445
E61.6 Vanadium deficiency	0.555	0.445
E61.5 Molybdenum deficiency	0.555	0.445
E61.4 Chromium deficiency	0.555	0.445
E61.3 Manganese deficiency	0.555	0.445
E61.0 Copper deficiency	0.555	0.445
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.556	0.444
M14.4 Arthropathy in amyloidosis	0.556	0.444
M14.3 Lipoid dermatoarthritis	0.556	0.444
M14.1 Crystal arthropathy in other metabolic disorders	0.556	0.444
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.556	0.444
M13.89 Other specified arthritis (Site unspecified)	0.560	0.440
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.563	0.437
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.563	0.437
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.563	0.437
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.563	0.437
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.563	0.437
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.563	0.437
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.563	0.437
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.563	0.437
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.563	0.437
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.563	0.437
M07.19 Arthritis mutilans (Site unspecified)	0.563	0.437
M07.18 Arthritis mutilans (Other)	0.563	0.437
M07.17 Arthritis mutilans (Ankle and foot)	0.563	0.437
M07.16 Arthritis mutilans (Lower leg)	0.563	0.437
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.563	0.437
M07.14 Arthritis mutilans (Hand)	0.563	0.437
M07.13 Arthritis mutilans (Forearm)	0.563	0.437
M07.12 Arthritis mutilans (Upper arm)	0.563	0.437
M07.11 Arthritis mutilans (Shoulder region)	0.563	0.437
M07.10 Arthritis mutilans (Multiple sites)	0.563	0.437
M07.29 Psoriatic spondylitis (Site unspecified)	0.563	0.437
M07.28 Psoriatic spondylitis (Other)	0.563	0.437
M07.27 Psoriatic spondylitis (Ankle and foot)	0.563	0.437
M07.26 Psoriatic spondylitis (Lower leg)	0.563	0.437
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.563	0.437
M07.24 Psoriatic spondylitis (Hand)	0.563	0.437
M07.23 Psoriatic spondylitis (Forearm)	0.563	0.437
M07.22 Psoriatic spondylitis (Upper arm)	0.563	0.437
M07.21 Psoriatic spondylitis (Shoulder region)	0.563	0.437
M07.20 Psoriatic spondylitis (Multiple sites)	0.563	0.437
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.563	0.437
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.563	0.437
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.563	0.437
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.563	0.437
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.563	0.437
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.563	0.437
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.563	0.437
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.563	0.437
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.563	0.437
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.563	0.437
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.563	0.437
M07.58 Arthropathy in ulcerative colitis (Other)	0.563	0.437
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.563	0.437
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.563	0.437
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.563	0.437
M07.54 Arthropathy in ulcerative colitis (Hand)	0.563	0.437
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.563	0.437
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.563	0.437
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.563	0.437
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.563	0.437
M07.69 Other enteropathic arthropathies (Site unspecified)	0.563	0.437
M07.68 Other enteropathic arthropathies (Other)	0.563	0.437
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.563	0.437
M07.66 Other enteropathic arthropathies (Lower leg)	0.563	0.437
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.563	0.437
M07.64 Other enteropathic arthropathies (Hand)	0.563	0.437
M07.63 Other enteropathic arthropathies (Forearm)	0.563	0.437
M07.62 Other enteropathic arthropathies (Upper arm)	0.563	0.437
M07.61 Other enteropathic arthropathies (Shoulder region)	0.563	0.437
M07.60 Other enteropathic arthropathies (Multiple sites)	0.563	0.437
M13.80 Other specified arthritis (Multiple sites)	0.570	0.429
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.571	0.429
M14.8 Arthropathies in other specified diseases classified elsewhere	0.575	0.425
E51.9 Thiamine deficiency, unspecified	0.579	0.421
E51.8 Other manifestations of thiamine deficiency	0.579	0.421
E51.1 Beriberi	0.579	0.421
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.581	0.419
M14.6 Neuropathic arthropathy	0.586	0.414
H36 Retinal disorders in diseases classified elsewhere	0.586	0.413
M14.2 Diabetic arthropathy	0.591	0.409
M13.19 Monoarthritis, not elsewhere classified (Site unspecified)	0.591	0.409
M13.18 Monoarthritis, not elsewhere classified (Other)	0.591	0.409
M13.17 Monoarthritis, not elsewhere classified (Ankle and foot)	0.591	0.409
M13.15 Monoarthritis, not elsewhere classified (Pelvic region and thigh)	0.591	0.409
M13.14 Monoarthritis, not elsewhere classified (Hand)	0.591	0.409
M13.13 Monoarthritis, not elsewhere classified (Forearm)	0.591	0.409
M13.12 Monoarthritis, not elsewhere classified (Upper arm)	0.591	0.409
M13.11 Monoarthritis, not elsewhere classified (Shoulder region)	0.591	0.409
M13.10 Monoarthritis, not elsewhere classified (Multiple sites)	0.591	0.409
M12.24 Villonodular synovitis (pigmented) (Hand)	0.592	0.408
M13.88 Other specified arthritis (Other)	0.595	0.404
M13.87 Other specified arthritis (Ankle and foot)	0.595	0.404
M13.85 Other specified arthritis (Pelvic region and thigh)	0.595	0.404
M13.84 Other specified arthritis (Hand)	0.595	0.404
M13.83 Other specified arthritis (Forearm)	0.595	0.404
M13.82 Other specified arthritis (Upper arm)	0.595	0.404
M13.81 Other specified arthritis (Shoulder region)	0.595	0.404
M12.30 Palindromic rheumatism (Multiple sites)	0.601	0.399
E53.9 Vitamin B deficiency, unspecified	0.604	0.396
E67 Other hyperalimentation	0.608	0.392
E68 Sequelae of hyperalimentation	0.608	0.392
E44 Protein-energy malnutrition of moderate and mild degree	0.608	0.391
E45 Retarded development following protein-energy malnutrition	0.608	0.391
E43 Unspecified severe protein-energy malnutrition	0.608	0.391
E42 Marasmic kwashiorkor	0.608	0.391
E41 Nutritional marasmus	0.608	0.391
E40 Kwashiorkor	0.608	0.391
M35.8 Other specified systemic involvement of connective tissue	0.609	0.391
M35.2 Behcet's disease	0.612	0.388
M12.39 Palindromic rheumatism (Site unspecified)	0.612	0.387
M12.38 Palindromic rheumatism (Other)	0.614	0.386
M12.37 Palindromic rheumatism (Ankle and foot)	0.614	0.386
M12.36 Palindromic rheumatism (Lower leg)	0.614	0.386
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.614	0.386
M12.34 Palindromic rheumatism (Hand)	0.614	0.386
M12.33 Palindromic rheumatism (Forearm)	0.614	0.386
M12.32 Palindromic rheumatism (Upper arm)	0.614	0.386
M12.31 Palindromic rheumatism (Shoulder region)	0.614	0.386
E50.9 Vitamin A deficiency, unspecified	0.619	0.381
E50.8 Other manifestations of vitamin A deficiency	0.619	0.381
E50.7 Other ocular manifestations of vitamin A deficiency	0.619	0.381
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.619	0.381
E50.5 Vitamin A deficiency with night blindness	0.619	0.381
E50.4 Vitamin A deficiency with keratomalacia	0.619	0.381
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.619	0.381
E50.2 Vitamin A deficiency with corneal xerosis	0.619	0.381
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.619	0.381
E50.0 Vitamin A deficiency with conjunctival xerosis	0.619	0.381
E63.9 Nutritional deficiency, unspecified	0.619	0.381
E63.8 Other specified nutritional deficiencies	0.619	0.381
E63.1 Imbalance of constituents of food intake	0.619	0.381
E63.0 Essential fatty acid [EFA] deficiency	0.619	0.381
E64.9 Sequelae of unspecified nutritional deficiency	0.619	0.381
E64.8 Sequelae of other nutritional deficiencies	0.619	0.381
E64.3 Sequelae of rickets	0.619	0.381
E64.2 Sequelae of vitamin C deficiency	0.619	0.381
E64.1 Sequelae of vitamin A deficiency	0.619	0.381
E64.0 Sequelae of protein-energy malnutrition	0.619	0.381
M13.86 Other specified arthritis (Lower leg)	0.621	0.379
E13.8 With unspecified complications	0.621	0.379
E13.7 With multiple complications	0.621	0.379
E13.6 With other specified complications	0.621	0.379
E13.5 With peripheral circulatory complications	0.621	0.379
E13.4 With neurological complications	0.621	0.379
E13.2 With renal complications	0.621	0.379
E13.1 With ketoacidosis	0.621	0.379
E13.0 With coma	0.621	0.379
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.623	0.377
M11.98 Crystal arthropathy, unspecified (Other)	0.623	0.377
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.623	0.377
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.623	0.377
M11.94 Crystal arthropathy, unspecified (Hand)	0.623	0.377
M11.93 Crystal arthropathy, unspecified (Forearm)	0.623	0.377
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.623	0.377
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.623	0.377
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.623	0.377
E66 Obesity	0.624	0.375
M12.09 Chronic postrheumatic arthropathy [Jaccoud] (Site unspecified)	0.625	0.375
M12.08 Chronic postrheumatic arthropathy [Jaccoud] (Other)	0.625	0.375
M12.07 Chronic postrheumatic arthropathy [Jaccoud] (Ankle and foot)	0.625	0.375
M12.06 Chronic postrheumatic arthropathy [Jaccoud] (Lower leg)	0.625	0.375
M12.05 Chronic postrheumatic arthropathy [Jaccoud] (Pelvic region and thigh)	0.625	0.375
M12.04 Chronic postrheumatic arthropathy [Jaccoud] (Hand)	0.625	0.375
M12.03 Chronic postrheumatic arthropathy [Jaccoud] (Forearm)	0.625	0.375
M12.02 Chronic postrheumatic arthropathy [Jaccoud] (Upper arm)	0.625	0.375
M12.01 Chronic postrheumatic arthropathy [Jaccoud] (Shoulder region)	0.625	0.375
M12.00 Chronic postrheumatic arthropathy [Jaccoud] (Multiple sites)	0.625	0.375
M12.19 Kaschin-Beck disease (Site unspecified)	0.625	0.375
M12.18 Kaschin-Beck disease (Other)	0.625	0.375
M12.17 Kaschin-Beck disease (Ankle and foot)	0.625	0.375
M12.16 Kaschin-Beck disease (Lower leg)	0.625	0.375
M12.15 Kaschin-Beck disease (Pelvic region and thigh)	0.625	0.375
M12.14 Kaschin-Beck disease (Hand)	0.625	0.375
M12.13 Kaschin-Beck disease (Forearm)	0.625	0.375
M12.12 Kaschin-Beck disease (Upper arm)	0.625	0.375
M12.11 Kaschin-Beck disease (Shoulder region)	0.625	0.375
M12.10 Kaschin-Beck disease (Multiple sites)	0.625	0.375
M12.49 Intermittent hydrarthrosis (Site unspecified)	0.625	0.375
M12.48 Intermittent hydrarthrosis (Other)	0.625	0.375
M12.47 Intermittent hydrarthrosis (Ankle and foot)	0.625	0.375
M12.46 Intermittent hydrarthrosis (Lower leg)	0.625	0.375
M12.45 Intermittent hydrarthrosis (Pelvic region and thigh)	0.625	0.375
M12.44 Intermittent hydrarthrosis (Hand)	0.625	0.375
M12.43 Intermittent hydrarthrosis (Forearm)	0.625	0.375
M12.42 Intermittent hydrarthrosis (Upper arm)	0.625	0.375

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations