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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3823418
log Bayes Factor = 85.6252
Chromosome 6   position 31,100,942  (GRCh37) Explore rs3823418 on Ensembl!
Variant rs3823418 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
M07.39 Other psoriatic arthropathies (Site unspecified)
1.000 0.000 0.000
L40.0 Psoriasis vulgaris
0.999 0.001 0.000
K90.0 Coeliac disease
0.000 0.002 0.998
M07.3 Other psoriatic arthropathies
0.997 0.003 0.000
E10.9 Without complications
0.000 0.006 0.994
E10.3 With ophthalmic complications
0.000 0.012 0.988
M07.30 Other psoriatic arthropathies (Multiple sites)
0.986 0.014 0.000
E10-E14 Diabetes mellitus
0.000 0.015 0.985
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.017 0.983
E10.4 With neurological complications
0.000 0.023 0.977
E10.1 With ketoacidosis
0.000 0.036 0.964
E05.9 Thyrotoxicosis, unspecified
0.000 0.038 0.962
E10.2 With renal complications
0.000 0.104 0.896
L40.1 Generalised pustular psoriasis
0.885 0.115 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.884 0.116 0.000
E10.5 With peripheral circulatory complications
0.000 0.123 0.877
M07.34 Other psoriatic arthropathies (Hand)
0.853 0.147 0.000
M07.38 Other psoriatic arthropathies (Other)
0.852 0.148 0.000
E50-E64 Other nutritional deficiencies
0.000 0.158 0.842
L40.8 Other psoriasis
0.842 0.158 0.000
L40.4 Guttate psoriasis
0.825 0.175 0.000
E10.0 With coma
0.000 0.193 0.807
M07.36 Other psoriatic arthropathies (Lower leg)
0.789 0.211 0.000
E53 Deficiency of other B group vitamins
0.000 0.250 0.750
E14 Unspecified diabetes mellitus
0.000 0.277 0.723
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.715 0.285 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.715 0.285 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.715 0.285 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.294 0.706
E06 Thyroiditis
0.000 0.299 0.701
E10.8 With unspecified complications
0.000 0.306 0.694
E10.6 With other specified complications
0.000 0.307 0.693
E53.8 Deficiency of other specified B group vitamins
0.000 0.317 0.683
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.317 0.683
E07 Other disorders of thyroid
0.000 0.317 0.683
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.330 0.670
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.370 0.629
E55 Vitamin D deficiency
0.000 0.376 0.624
E03.8 Other specified hypothyroidism
0.000 0.380 0.620
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.396 0.604
E63 Other nutritional deficiencies
0.000 0.396 0.604
E56 Other vitamin deficiencies
0.000 0.396 0.604
E51 Thiamine deficiency
0.000 0.396 0.604
E50 Vitamin A deficiency
0.000 0.396 0.604
E60 Dietary zinc deficiency
0.000 0.396 0.604
E59 Dietary selenium deficiency
0.000 0.396 0.604
E58 Dietary calcium deficiency
0.000 0.396 0.604
E54 Ascorbic acid deficiency
0.000 0.396 0.604
E52 Niacin deficiency [pellagra]
0.000 0.396 0.604
E65-E68 Obesity and other hyperalimentation
0.000 0.398 0.602
E14.3 With ophthalmic complications
0.000 0.428 0.572
E61 Deficiency of other nutrient elements
0.000 0.442 0.558
E53.9 Vitamin B deficiency, unspecified
0.000 0.462 0.538
E53.1 Pyridoxine deficiency
0.000 0.462 0.538
E53.0 Riboflavin deficiency
0.000 0.462 0.538
E06.3 Autoimmune thyroiditis
0.000 0.465 0.535
E07.9 Disorder of thyroid, unspecified
0.000 0.478 0.522
E14.8 With unspecified complications
0.000 0.482 0.518
E14.7 With multiple complications
0.000 0.482 0.518
E14.6 With other specified complications
0.000 0.482 0.518
E14.2 Withrenal complications
0.000 0.482 0.518
E14.1 With ketoacidosis
0.000 0.482 0.518
E14.0 With coma
0.000 0.482 0.518
E20-E35 Disorders of other endocrine glands
0.000 0.483 0.517
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E13 Other specified diabetes mellitus
0.001 0.491 0.508
E14.4 With neurological complications
0.000 0.491 0.509
E12.9 Without complications
0.000 0.493 0.506
E12.8 With unspecified complications
0.000 0.493 0.506
E12.7 With multiple complications
0.000 0.493 0.506
E12.6 With other specified complications
0.000 0.493 0.506
E12.5 With peripheral circulatory complications
0.000 0.493 0.506
E12.4 With neurological complications
0.000 0.493 0.506
E12.3 With ophthalmic complications
0.000 0.493 0.506
E12.2 With renal complications
0.000 0.493 0.506
E12.1 With ketoacidosis
0.000 0.493 0.506
E12.0 With coma
0.000 0.493 0.506
E06.5 Other chronic thyroiditis
0.000 0.497 0.503
E06.4 Drug-induced thyroiditis
0.000 0.497 0.503
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.497 0.503
E06.1 Subacute thyroiditis
0.000 0.497 0.503
E06.0 Acute thyroiditis
0.000 0.497 0.503
E14.9 Without complications
0.000 0.498 0.502
E40-E46 Malnutrition
0.001 0.500 0.500
E14.5 With peripheral circulatory complications
0.000 0.502 0.497
E07.1 Dyshormogenetic goitre
0.000 0.510 0.490
E07.0 Hypersecretion of calcitonin
0.000 0.510 0.490
E15 Nondiabetic hypoglycaemic coma
0.000 0.520 0.480
E55.9 Vitamin D deficiency, unspecified
0.000 0.532 0.468
E27 Other disorders of adrenal gland
0.000 0.539 0.461
E27.1 Primary adrenocortical insufficiency
0.000 0.547 0.453
E55.0 Rickets, active
0.000 0.552 0.447
E06.9 Thyroiditis, unspecified
0.000 0.554 0.446
E16 Other disorders of pancreatic internal secretion
0.000 0.555 0.445
M07 Psoriatic and enteropathic arthropathies
0.430 0.561 0.009
E50.9 Vitamin A deficiency, unspecified
0.000 0.567 0.433
E50.8 Other manifestations of vitamin A deficiency
0.000 0.567 0.433
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.567 0.433
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.567 0.433
E50.5 Vitamin A deficiency with night blindness
0.000 0.567 0.433
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.567 0.433
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.567 0.433
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.567 0.433
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.567 0.433
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.567 0.433
E51.9 Thiamine deficiency, unspecified
0.000 0.567 0.433
E51.8 Other manifestations of thiamine deficiency
0.000 0.567 0.433
E51.2 Wernicke's encephalopathy
0.000 0.567 0.433
E51.1 Beriberi
0.000 0.567 0.433
E56.9 Vitamin deficiency, unspecified
0.000 0.567 0.433
E56.8 Deficiency of other vitamins
0.000 0.567 0.433
E56.1 Deficiency of vitamin K
0.000 0.567 0.433
E56.0 Deficiency of vitamin E
0.000 0.567 0.433
E63.9 Nutritional deficiency, unspecified
0.000 0.567 0.433
E63.8 Other specified nutritional deficiencies
0.000 0.567 0.433
E63.1 Imbalance of constituents of food intake
0.000 0.567 0.433
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.567 0.433
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.567 0.433
E64.8 Sequelae of other nutritional deficiencies
0.000 0.567 0.433
E64.3 Sequelae of rickets
0.000 0.567 0.433
E64.2 Sequelae of vitamin C deficiency
0.000 0.567 0.433
E64.1 Sequelae of vitamin A deficiency
0.000 0.567 0.433
E64.0 Sequelae of protein-energy malnutrition
0.000 0.567 0.433
E28 Ovarian dysfunction
0.000 0.567 0.433
E67 Other hyperalimentation
0.000 0.569 0.431
E68 Sequelae of hyperalimentation
0.000 0.569 0.431
E07.8 Other specified disorders of thyroid
0.000 0.589 0.411
E34 Other endocrine disorders
0.000 0.590 0.410
E66 Obesity
0.000 0.591 0.409
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.594 0.405
E61.9 Deficiency of nutrient element, unspecified
0.000 0.600 0.400
E61.8 Deficiency of other specified nutrient elements
0.000 0.600 0.400
E61.7 Deficiency of multiple nutrient elements
0.000 0.600 0.400
E61.6 Vanadium deficiency
0.000 0.600 0.400
E61.5 Molybdenum deficiency
0.000 0.600 0.400
E61.4 Chromium deficiency
0.000 0.600 0.400
E61.3 Manganese deficiency
0.000 0.600 0.400
E61.2 Magnesium deficiency
0.000 0.600 0.400
E61.0 Copper deficiency
0.000 0.600 0.400
E29 Testicular dysfunction
0.000 0.602 0.398
E66.8 Other obesity
0.000 0.608 0.392
K90 Intestinal malabsorption
0.000 0.613 0.387
E20 Hypoparathyroidism
0.000 0.618 0.382
E28.3 Primary ovarian failure
0.000 0.621 0.379
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.629 0.370
E32 Diseases of thymus
0.000 0.629 0.370
E31 Polyglandular dysfunction
0.000 0.629 0.370
E30 Disorders of puberty, not elsewhere classified
0.000 0.629 0.370
E13.8 With unspecified complications
0.001 0.635 0.364
E13.7 With multiple complications
0.001 0.635 0.364
E13.6 With other specified complications
0.001 0.635 0.364
E13.5 With peripheral circulatory complications
0.001 0.635 0.364
E13.4 With neurological complications
0.001 0.635 0.364
E13.3 With ophthalmic complications
0.001 0.635 0.364
E13.2 With renal complications
0.001 0.635 0.364
E13.1 With ketoacidosis
0.001 0.635 0.364
E13.0 With coma
0.001 0.635 0.364
E04 Other non-toxic goitre
0.000 0.638 0.362
E65 Localised adiposity
0.000 0.640 0.359
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.641 0.358
E45 Retarded development following protein-energy malnutrition
0.001 0.641 0.358
E43 Unspecified severe protein-energy malnutrition
0.001 0.641 0.358
E42 Marasmic kwashiorkor
0.001 0.641 0.358
E41 Nutritional marasmus
0.001 0.641 0.358
E40 Kwashiorkor
0.001 0.641 0.358
E26 Hyperaldosteronism
0.000 0.645 0.355
E61.1 Iron deficiency
0.000 0.646 0.354
E22 Hyperfunction of pituitary gland
0.000 0.661 0.339
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.667 0.332
E34.8 Other specified endocrine disorders
0.000 0.668 0.332
E27.5 Adrenomedullary hyperfunction
0.000 0.669 0.331
E27.0 Other adrenocortical overactivity
0.000 0.669 0.331
E27.8 Other specified disorders of adrenal gland
0.000 0.675 0.325
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.681 0.319
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.681 0.319
E16.4 Abnormal secretion of gastrin
0.000 0.681 0.319
E16.3 Increased secretion of glucagon
0.000 0.681 0.319
E16.2 Hypoglycaemia, unspecified
0.000 0.683 0.317
E27.2 Addisonian crisis
0.000 0.684 0.316
M07.6 Other enteropathic arthropathies
0.309 0.685 0.006
M07.5 Arthropathy in ulcerative colitis
0.309 0.685 0.006
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.309 0.685 0.006
M07.2 Psoriatic spondylitis
0.309 0.685 0.006
M07.1 Arthritis mutilans
0.309 0.685 0.006
M07.0 Distal interphalangeal psoriatic arthropathy
0.309 0.685 0.006
E29.1 Testicular hypofunction
0.000 0.687 0.313
E28.9 Ovarian dysfunction, unspecified
0.000 0.689 0.311
E28.8 Other ovarian dysfunction
0.000 0.689 0.311
E28.1 Androgen excess
0.000 0.689 0.311
E28.0 Oestrogen excess
0.000 0.689 0.311
E67.8 Other specified hyperalimentation
0.000 0.690 0.309
E67.3 Hypervitaminosis D
0.000 0.690 0.309
E67.2 Megavitamin-B6 syndrome
0.000 0.690 0.309
E67.1 Hypercarotenaemia
0.000 0.690 0.309
E67.0 Hypervitaminosis A
0.000 0.690 0.309
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.692 0.308
E34.9 Endocrine disorder, unspecified
0.000 0.692 0.308
E25 Adrenogenital disorders
0.000 0.693 0.306
E16.1 Other hypoglycaemia
0.000 0.701 0.299
E28.2 Polycystic ovarian syndrome
0.000 0.703 0.296
E34.5 Androgen resistance syndrome
0.000 0.706 0.294
E34.4 Constitutional tall stature
0.000 0.706 0.294
E34.3 Short stature, not elsewhere classified
0.000 0.706 0.294
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.706 0.294
E34.1 Other hypersecretion of intestinal hormones
0.000 0.706 0.294
K90.8 Other intestinal malabsorption
0.000 0.706 0.294
E66.1 Drug-induced obesity
0.000 0.706 0.293
E20.9 Hypoparathyroidism, unspecified
0.000 0.714 0.286
E29.9 Testicular dysfunction, unspecified
0.000 0.714 0.285
E29.8 Other testicular dysfunction
0.000 0.714 0.285
E29.0 Testicular hyperfunction
0.000 0.714 0.285
E34.0 Carcinoid syndrome
0.000 0.721 0.279
K90.3 Pancreatic steatorrhoea
0.000 0.723 0.277
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.723 0.277
K90.1 Tropical sprue
0.000 0.723 0.277
E20.8 Other hypoparathyroidism
0.000 0.726 0.274
E20.1 Pseudohypoparathyroidism
0.000 0.726 0.274
E20.0 Idiopathic hypoparathyroidism
0.000 0.726 0.274
E30.9 Disorder of puberty, unspecified
0.000 0.734 0.266
E30.8 Other disorders of puberty
0.000 0.734 0.266
E30.1 Precocious puberty
0.000 0.734 0.266
E30.0 Delayed puberty
0.000 0.734 0.266
E31.9 Polyglandular dysfunction, unspecified
0.000 0.734 0.266
E31.8 Other polyglandular dysfunction
0.000 0.734 0.266
E31.1 Polyglandular hyperfunction
0.000 0.734 0.266
E31.0 Autoimmune polyglandular failure
0.000 0.734 0.266
E32.9 Disease of thymus, unspecified
0.000 0.734 0.266
E32.8 Other diseases of thymus
0.000 0.734 0.266
E32.1 Abscess of thymus
0.000 0.734 0.266
E32.0 Persistent hyperplasia of thymus
0.000 0.734 0.266
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.734 0.266
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.734 0.266
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.734 0.266
E22.1 Hyperprolactinaemia
0.000 0.740 0.260
E04.8 Other specified non-toxic goitre
0.000 0.740 0.260
E44.1 Mild protein-energy malnutrition
0.001 0.742 0.257
E44.0 Moderate protein-energy malnutrition
0.001 0.742 0.257
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.743 0.257
E26.9 Hyperaldosteronism, unspecified
0.000 0.745 0.255
E26.8 Other hyperaldosteronism
0.000 0.745 0.255
E26.1 Secondary hyperaldosteronism
0.000 0.745 0.255
E22.0 Acromegaly and pituitary gigantism
0.000 0.746 0.254
K90.9 Intestinal malabsorption, unspecified
0.000 0.748 0.252
E24 Cushing's syndrome
0.001 0.755 0.245
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.757 0.243
E22.8 Other hyperfunction of pituitary gland
0.000 0.757 0.243
E04.0 Non-toxic diffuse goitre
0.000 0.757 0.243
E26.0 Primary hyperaldosteronism
0.000 0.760 0.240
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.764 0.236
E66.0 Obesity due to excess calories
0.000 0.765 0.235
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.769 0.231
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.221 0.774 0.005
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.221 0.774 0.005
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.221 0.774 0.005
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.221 0.774 0.005
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.221 0.774 0.005
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.221 0.774 0.005
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.221 0.774 0.005
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.221 0.774 0.005
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.221 0.774 0.005
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.221 0.774 0.005
M07.19 Arthritis mutilans (Site unspecified)
0.221 0.774 0.005
M07.18 Arthritis mutilans (Other)
0.221 0.774 0.005
M07.17 Arthritis mutilans (Ankle and foot)
0.221 0.774 0.005
M07.16 Arthritis mutilans (Lower leg)
0.221 0.774 0.005
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.221 0.774 0.005
M07.14 Arthritis mutilans (Hand)
0.221 0.774 0.005
M07.13 Arthritis mutilans (Forearm)
0.221 0.774 0.005
M07.12 Arthritis mutilans (Upper arm)
0.221 0.774 0.005
M07.11 Arthritis mutilans (Shoulder region)
0.221 0.774 0.005
M07.10 Arthritis mutilans (Multiple sites)
0.221 0.774 0.005
M07.29 Psoriatic spondylitis (Site unspecified)
0.221 0.774 0.005
M07.28 Psoriatic spondylitis (Other)
0.221 0.774 0.005
M07.27 Psoriatic spondylitis (Ankle and foot)
0.221 0.774 0.005
M07.26 Psoriatic spondylitis (Lower leg)
0.221 0.774 0.005
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.221 0.774 0.005
M07.24 Psoriatic spondylitis (Hand)
0.221 0.774 0.005
M07.23 Psoriatic spondylitis (Forearm)
0.221 0.774 0.005
M07.22 Psoriatic spondylitis (Upper arm)
0.221 0.774 0.005
M07.21 Psoriatic spondylitis (Shoulder region)
0.221 0.774 0.005
M07.20 Psoriatic spondylitis (Multiple sites)
0.221 0.774 0.005
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.221 0.774 0.005
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.221 0.774 0.005
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.221 0.774 0.005
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.221 0.774 0.005
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.221 0.774 0.005
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.221 0.774 0.005
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.221 0.774 0.005
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.221 0.774 0.005
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.221 0.774 0.005
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.221 0.774 0.005
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.221 0.774 0.005
M07.58 Arthropathy in ulcerative colitis (Other)
0.221 0.774 0.005
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.221 0.774 0.005
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.221 0.774 0.005
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.221 0.774 0.005
M07.54 Arthropathy in ulcerative colitis (Hand)
0.221 0.774 0.005
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.221 0.774 0.005
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.221 0.774 0.005
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.221 0.774 0.005
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.221 0.774 0.005
M07.69 Other enteropathic arthropathies (Site unspecified)
0.221 0.774 0.005
M07.68 Other enteropathic arthropathies (Other)
0.221 0.774 0.005
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.221 0.774 0.005
M07.66 Other enteropathic arthropathies (Lower leg)
0.221 0.774 0.005
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.221 0.774 0.005
M07.64 Other enteropathic arthropathies (Hand)
0.221 0.774 0.005
M07.63 Other enteropathic arthropathies (Forearm)
0.221 0.774 0.005
M07.62 Other enteropathic arthropathies (Upper arm)
0.221 0.774 0.005
M07.61 Other enteropathic arthropathies (Shoulder region)
0.221 0.774 0.005
M07.60 Other enteropathic arthropathies (Multiple sites)
0.221 0.774 0.005
E25.9 Adrenogenital disorder, unspecified
0.000 0.780 0.220
E25.8 Other adrenogenital disorders
0.000 0.780 0.220
E04.1 Non-toxic single thyroid nodule
0.000 0.785 0.215
E27.9 Disorder of adrenal gland, unspecified
0.001 0.798 0.202
L40-L45 Papulosquamous disorders
0.197 0.803 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.804 0.196
E23 Hypofunction and other disorders of pituitary gland
0.000 0.805 0.194
E04.2 Non-toxic multinodular goitre
0.000 0.807 0.193
J47 Bronchiectasis
0.000 0.808 0.192
E24.8 Other Cushing's syndrome
0.001 0.824 0.176
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.824 0.176
E24.3 Ectopic ACTH syndrome
0.001 0.824 0.176
E24.2 Drug-induced Cushing's syndrome
0.001 0.824 0.176
E24.1 Nelson's syndrome
0.001 0.824 0.176
E13.9 Without complications
0.001 0.832 0.166
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.836 0.164
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.839 0.160
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.843 0.156
E46 Unspecified protein-energy malnutrition
0.002 0.846 0.153
L44 Other papulosquamous disorders
0.141 0.858 0.000
L41 Parapsoriasis
0.141 0.858 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.141 0.858 0.000
M35.3 Polymyalgia rheumatica
0.000 0.859 0.141
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.860 0.139
E23.1 Drug-induced hypopituitarism
0.000 0.860 0.139
E24.9 Cushing's syndrome, unspecified
0.001 0.865 0.134
E23.2 Diabetes insipidus
0.000 0.867 0.133
E23.6 Other disorders of pituitary gland
0.000 0.871 0.129
E24.0 Pituitary-dependent Cushing's disease
0.001 0.876 0.123
E23.7 Disorder of pituitary gland, unspecified
0.000 0.878 0.121
L42 Pityriasis rosea
0.121 0.879 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.885 0.115
E21.2 Other hyperparathyroidism
0.000 0.885 0.115
M35 Other systemic involvement of connective tissue
0.000 0.885 0.115
M35.0 Sicca syndrome [Sjogren]
0.000 0.892 0.108
L41.9 Parapsoriasis, unspecified
0.102 0.898 0.000
L41.8 Other parapsoriasis
0.102 0.898 0.000
L41.5 Retiform parapsoriasis
0.102 0.898 0.000
L41.4 Large plaque parapsoriasis
0.102 0.898 0.000
L41.3 Small plaque parapsoriasis
0.102 0.898 0.000
L41.2 Lymphomatoid papulosis
0.102 0.898 0.000
L41.1 Pityriasis lichenoides chronica
0.102 0.898 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.102 0.898 0.000
L44.9 Papulosquamous disorder, unspecified
0.102 0.898 0.000
L44.8 Other specified papulosquamous disorders
0.102 0.898 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.102 0.898 0.000
L44.3 Lichen ruber moniliformis
0.102 0.898 0.000
L44.2 Lichen striatus
0.102 0.898 0.000
L44.1 Lichen nitidus
0.102 0.898 0.000
L44.0 Pityriasis rubra pilaris
0.102 0.898 0.000
E70-E90 Metabolic disorders
0.000 0.900 0.100
M35.1 Other overlap syndromes
0.000 0.903 0.097
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.904 0.096
E21.0 Primary hyperparathyroidism
0.000 0.905 0.095
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.908 0.092
E73 Lactose intolerance
0.000 0.911 0.089
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.911 0.089
M06.9 Rheumatoid arthritis, unspecified
0.000 0.911 0.089
E83 Disorders of mineral metabolism
0.000 0.917 0.083
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.917 0.082
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.917 0.082
M35.5 Multifocal fibrosclerosis
0.000 0.917 0.082
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.917 0.082
M35.2 Behcet's disease
0.000 0.917 0.082
E73.9 Lactose intolerance, unspecified
0.000 0.918 0.082
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.918 0.082
E85 Amyloidosis
0.000 0.919 0.081
E21.3 Hyperparathyroidism, unspecified
0.000 0.921 0.079
L43 Lichen planus
0.078 0.921 0.000
M35.7 Hypermobility syndrome
0.000 0.922 0.078
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.922 0.078
M35.8 Other specified systemic involvement of connective tissue
0.000 0.922 0.078
E74 Other disorders of carbohydrate metabolism
0.000 0.923 0.077
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.925 0.075
E83.4 Disorders of magnesium metabolism
0.000 0.925 0.075
E83.3 Disorders of phosphorus metabolism
0.000 0.926 0.074
E11 Non-insulin-dependent diabetes mellitus
0.000 0.927 0.073
E84 Cystic fibrosis
0.000 0.928 0.072
E79 Disorders of purine and pyrimidine metabolism
0.000 0.928 0.072
E77 Disorders of glycoprotein metabolism
0.000 0.928 0.072
E76 Disorders of glycosaminoglycan metabolism
0.000 0.928 0.072
E72 Other disorders of amino-acid metabolism
0.000 0.928 0.072
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.928 0.072
E70 Disorders of aromatic amino-acid metabolism
0.000 0.928 0.072
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.928 0.072
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.929 0.071
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.929 0.071
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.930 0.070
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.931 0.069
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.932 0.068
E11.3 With ophthalmic complications
0.000 0.934 0.066
E85.9 Amyloidosis, unspecified
0.000 0.934 0.066
E23.0 Hypopituitarism
0.001 0.935 0.064
E73.8 Other lactose intolerance
0.000 0.936 0.064
E73.1 Secondary lactase deficiency
0.000 0.936 0.064
E73.0 Congenital lactase deficiency
0.000 0.936 0.064
Z93.2 Ileostomy status
0.000 0.938 0.062
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.938 0.062
E85.4 Organ-limited amyloidosis
0.000 0.939 0.061
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.939 0.061
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.940 0.060
E83.8 Other disorders of mineral metabolism
0.000 0.940 0.060
E83.2 Disorders of zinc metabolism
0.000 0.940 0.060
E83.0 Disorders of copper metabolism
0.000 0.940 0.060
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.941 0.059
E85.8 Other amyloidosis
0.000 0.942 0.058
E85.3 Secondary systemic amyloidosis
0.000 0.942 0.058
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.942 0.058
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.942 0.058
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.942 0.058
N20.1 Calculus of ureter
0.057 0.943 0.000
L43.3 Subacute (active) lichen planus
0.056 0.943 0.000
L43.2 Lichenoid drug reaction
0.056 0.943 0.000
L43.1 Bullous lichen planus
0.056 0.943 0.000
L43.0 Hypertrophic lichen planus
0.056 0.943 0.000
N20.0 Calculus of kidney
0.056 0.944 0.000
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.944 0.055
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.944 0.055
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.944 0.055
E74.2 Disorders of galactose metabolism
0.000 0.944 0.055
E74.1 Disorders of fructose metabolism
0.000 0.944 0.055
E74.0 Glycogen storage disease
0.000 0.944 0.055
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.000 0.944 0.056
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.945 0.055
E11.8 With unspecified complications
0.000 0.946 0.054
N20 Calculus of kidney and ureter
0.053 0.947 0.000
E11.7 With multiple complications
0.000 0.948 0.052
M06 Other rheumatoid arthritis
0.007 0.948 0.045
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.948 0.052
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.948 0.052
E70.3 Albinism
0.000 0.948 0.052
E70.2 Disorders of tyrosine metabolism
0.000 0.948 0.052
E70.1 Other hyperphenylalaninaemias
0.000 0.948 0.052
E70.0 Classical phenylketonuria
0.000 0.948 0.052
E71.3 Disorders of fatty-acid metabolism
0.000 0.948 0.052
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.948 0.052
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.948 0.052
E71.0 Maple-syrup-urine disease
0.000 0.948 0.052
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.948 0.052
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.948 0.052
E72.5 Disorders of glycine metabolism
0.000 0.948 0.052
E72.4 Disorders of ornithine metabolism
0.000 0.948 0.052
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.948 0.052
E72.2 Disorders of urea cycle metabolism
0.000 0.948 0.052
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.948 0.052
E72.0 Disorders of amino-acid transport
0.000 0.948 0.052
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.948 0.052
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.948 0.052
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.948 0.052
E76.2 Other mucopolysaccharidoses
0.000 0.948 0.052
E76.1 Mucopolysaccharidosis, type II
0.000 0.948 0.052
E76.0 Mucopolysaccharidosis, type I
0.000 0.948 0.052
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.948 0.052
E77.8 Other disorders of glycoprotein metabolism
0.000 0.948 0.052
E77.1 Defects in glycoprotein degradation
0.000 0.948 0.052
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.948 0.052
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.948 0.052

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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