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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3823419
log Bayes Factor = 85.964
Chromosome 6   position 31,101,001  (GRCh37) Explore rs3823419 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.000 1.000
L40.0 Psoriasis vulgaris
0.999 0.001 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.999 0.001 0.000
K90.0 Coeliac disease
0.000 0.002 0.998
E10.9 Without complications
0.000 0.003 0.997
M07.3 Other psoriatic arthropathies
0.996 0.004 0.000
E10-E14 Diabetes mellitus
0.000 0.012 0.988
E10.3 With ophthalmic complications
0.000 0.013 0.987
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.013 0.987
M07.30 Other psoriatic arthropathies (Multiple sites)
0.980 0.020 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.020 0.980
E10.4 With neurological complications
0.000 0.024 0.976
E10.1 With ketoacidosis
0.000 0.039 0.961
E10.5 With peripheral circulatory complications
0.000 0.097 0.903
E10.2 With renal complications
0.000 0.101 0.899
L40.1 Generalised pustular psoriasis
0.886 0.114 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.883 0.117 0.000
E50-E64 Other nutritional deficiencies
0.000 0.138 0.862
M07.34 Other psoriatic arthropathies (Hand)
0.853 0.147 0.000
M07.38 Other psoriatic arthropathies (Other)
0.851 0.149 0.000
L40.8 Other psoriasis
0.844 0.156 0.000
L40.4 Guttate psoriasis
0.825 0.175 0.000
E10.0 With coma
0.000 0.195 0.805
M07.36 Other psoriatic arthropathies (Lower leg)
0.790 0.210 0.000
E53 Deficiency of other B group vitamins
0.000 0.238 0.762
E10.8 With unspecified complications
0.000 0.259 0.741
E06 Thyroiditis
0.000 0.280 0.720
E14 Unspecified diabetes mellitus
0.000 0.281 0.719
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.714 0.286 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.714 0.286 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.714 0.286 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.714 0.286 0.000
E12 Malnutrition-related diabetes mellitus
0.000 0.292 0.708
E10.6 With other specified complications
0.000 0.300 0.700
E53.8 Deficiency of other specified B group vitamins
0.000 0.309 0.691
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.319 0.681
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.321 0.679
E55 Vitamin D deficiency
0.000 0.323 0.677
E07 Other disorders of thyroid
0.000 0.330 0.670
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.380 0.620
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.382 0.618
E63 Other nutritional deficiencies
0.000 0.382 0.618
E56 Other vitamin deficiencies
0.000 0.382 0.618
E51 Thiamine deficiency
0.000 0.382 0.618
E50 Vitamin A deficiency
0.000 0.382 0.618
E60 Dietary zinc deficiency
0.000 0.382 0.618
E59 Dietary selenium deficiency
0.000 0.382 0.618
E58 Dietary calcium deficiency
0.000 0.382 0.618
E54 Ascorbic acid deficiency
0.000 0.382 0.618
E52 Niacin deficiency [pellagra]
0.000 0.382 0.618
E03.8 Other specified hypothyroidism
0.000 0.383 0.616
E65-E68 Obesity and other hyperalimentation
0.000 0.397 0.603
E61 Deficiency of other nutrient elements
0.000 0.425 0.574
E06.3 Autoimmune thyroiditis
0.000 0.434 0.566
E14.3 With ophthalmic complications
0.000 0.438 0.562
E53.9 Vitamin B deficiency, unspecified
0.000 0.453 0.546
E53.1 Pyridoxine deficiency
0.000 0.453 0.546
E53.0 Riboflavin deficiency
0.000 0.453 0.546
E55.9 Vitamin D deficiency, unspecified
0.000 0.456 0.544
E20-E35 Disorders of other endocrine glands
0.000 0.468 0.532
E06.5 Other chronic thyroiditis
0.000 0.483 0.516
E06.4 Drug-induced thyroiditis
0.000 0.483 0.516
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.483 0.516
E06.1 Subacute thyroiditis
0.000 0.483 0.516
E06.0 Acute thyroiditis
0.000 0.483 0.516
E14.8 With unspecified complications
0.000 0.484 0.515
E14.7 With multiple complications
0.000 0.484 0.515
E14.6 With other specified complications
0.000 0.484 0.515
E14.2 Withrenal complications
0.000 0.484 0.515
E14.1 With ketoacidosis
0.000 0.484 0.515
E14.0 With coma
0.000 0.484 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E13 Other specified diabetes mellitus
0.001 0.489 0.510
E12.9 Without complications
0.000 0.492 0.508
E12.8 With unspecified complications
0.000 0.492 0.508
E12.7 With multiple complications
0.000 0.492 0.508
E12.6 With other specified complications
0.000 0.492 0.508
E12.5 With peripheral circulatory complications
0.000 0.492 0.508
E12.4 With neurological complications
0.000 0.492 0.508
E12.3 With ophthalmic complications
0.000 0.492 0.508
E12.2 With renal complications
0.000 0.492 0.508
E12.1 With ketoacidosis
0.000 0.492 0.508
E12.0 With coma
0.000 0.492 0.508
E14.4 With neurological complications
0.000 0.495 0.505
E14.9 Without complications
0.000 0.496 0.504
E07.9 Disorder of thyroid, unspecified
0.000 0.497 0.502
E40-E46 Malnutrition
0.001 0.498 0.501
E14.5 With peripheral circulatory complications
0.000 0.506 0.494
E15 Nondiabetic hypoglycaemic coma
0.000 0.513 0.487
E55.0 Rickets, active
0.000 0.515 0.485
E07.1 Dyshormogenetic goitre
0.000 0.520 0.480
E07.0 Hypersecretion of calcitonin
0.000 0.520 0.480
E27 Other disorders of adrenal gland
0.000 0.531 0.469
E27.1 Primary adrenocortical insufficiency
0.000 0.540 0.460
E16 Other disorders of pancreatic internal secretion
0.000 0.541 0.459
E06.9 Thyroiditis, unspecified
0.000 0.544 0.456
E28 Ovarian dysfunction
0.000 0.549 0.451
E50.9 Vitamin A deficiency, unspecified
0.000 0.557 0.443
E50.8 Other manifestations of vitamin A deficiency
0.000 0.557 0.443
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.557 0.443
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.557 0.443
E50.5 Vitamin A deficiency with night blindness
0.000 0.557 0.443
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.557 0.443
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.557 0.443
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.557 0.443
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.557 0.443
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.557 0.443
E51.9 Thiamine deficiency, unspecified
0.000 0.557 0.443
E51.8 Other manifestations of thiamine deficiency
0.000 0.557 0.443
E51.2 Wernicke's encephalopathy
0.000 0.557 0.443
E51.1 Beriberi
0.000 0.557 0.443
E56.9 Vitamin deficiency, unspecified
0.000 0.557 0.443
E56.8 Deficiency of other vitamins
0.000 0.557 0.443
E56.1 Deficiency of vitamin K
0.000 0.557 0.443
E56.0 Deficiency of vitamin E
0.000 0.557 0.443
E63.9 Nutritional deficiency, unspecified
0.000 0.557 0.443
E63.8 Other specified nutritional deficiencies
0.000 0.557 0.443
E63.1 Imbalance of constituents of food intake
0.000 0.557 0.443
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.557 0.443
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.557 0.443
E64.8 Sequelae of other nutritional deficiencies
0.000 0.557 0.443
E64.3 Sequelae of rickets
0.000 0.557 0.443
E64.2 Sequelae of vitamin C deficiency
0.000 0.557 0.443
E64.1 Sequelae of vitamin A deficiency
0.000 0.557 0.443
E64.0 Sequelae of protein-energy malnutrition
0.000 0.557 0.443
M07 Psoriatic and enteropathic arthropathies
0.431 0.565 0.004
E67 Other hyperalimentation
0.000 0.568 0.432
E68 Sequelae of hyperalimentation
0.000 0.568 0.432
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.572 0.427
E34 Other endocrine disorders
0.000 0.581 0.419
E29 Testicular dysfunction
0.000 0.587 0.413
E61.9 Deficiency of nutrient element, unspecified
0.000 0.588 0.412
E61.8 Deficiency of other specified nutrient elements
0.000 0.588 0.412
E61.7 Deficiency of multiple nutrient elements
0.000 0.588 0.412
E61.6 Vanadium deficiency
0.000 0.588 0.412
E61.5 Molybdenum deficiency
0.000 0.588 0.412
E61.4 Chromium deficiency
0.000 0.588 0.412
E61.3 Manganese deficiency
0.000 0.588 0.412
E61.2 Magnesium deficiency
0.000 0.588 0.412
E61.0 Copper deficiency
0.000 0.588 0.412
E66 Obesity
0.000 0.589 0.411
E07.8 Other specified disorders of thyroid
0.000 0.599 0.401
E28.3 Primary ovarian failure
0.000 0.605 0.395
E66.8 Other obesity
0.000 0.606 0.394
E20 Hypoparathyroidism
0.000 0.611 0.389
E26 Hyperaldosteronism
0.000 0.617 0.383
K90 Intestinal malabsorption
0.000 0.618 0.382
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.618 0.381
E32 Diseases of thymus
0.000 0.618 0.381
E31 Polyglandular dysfunction
0.000 0.618 0.381
E30 Disorders of puberty, not elsewhere classified
0.000 0.618 0.381
E61.1 Iron deficiency
0.000 0.632 0.368
E13.8 With unspecified complications
0.001 0.634 0.366
E13.7 With multiple complications
0.001 0.634 0.366
E13.6 With other specified complications
0.001 0.634 0.366
E13.5 With peripheral circulatory complications
0.001 0.634 0.366
E13.4 With neurological complications
0.001 0.634 0.366
E13.3 With ophthalmic complications
0.001 0.634 0.366
E13.2 With renal complications
0.001 0.634 0.366
E13.1 With ketoacidosis
0.001 0.634 0.366
E13.0 With coma
0.001 0.634 0.366
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.640 0.360
E45 Retarded development following protein-energy malnutrition
0.001 0.640 0.360
E43 Unspecified severe protein-energy malnutrition
0.001 0.640 0.360
E42 Marasmic kwashiorkor
0.001 0.640 0.360
E41 Nutritional marasmus
0.001 0.640 0.360
E40 Kwashiorkor
0.001 0.640 0.360
E65 Localised adiposity
0.000 0.642 0.358
E22 Hyperfunction of pituitary gland
0.000 0.647 0.352
E04 Other non-toxic goitre
0.000 0.658 0.342
E34.8 Other specified endocrine disorders
0.000 0.660 0.339
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.662 0.338
E27.5 Adrenomedullary hyperfunction
0.000 0.663 0.337
E27.0 Other adrenocortical overactivity
0.000 0.663 0.337
E16.2 Hypoglycaemia, unspecified
0.000 0.665 0.335
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.671 0.329
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.671 0.329
E16.4 Abnormal secretion of gastrin
0.000 0.671 0.329
E16.3 Increased secretion of glucagon
0.000 0.671 0.329
E27.8 Other specified disorders of adrenal gland
0.000 0.671 0.329
E29.1 Testicular hypofunction
0.000 0.672 0.328
E28.9 Ovarian dysfunction, unspecified
0.000 0.676 0.323
E28.8 Other ovarian dysfunction
0.000 0.676 0.323
E28.1 Androgen excess
0.000 0.676 0.323
E28.0 Oestrogen excess
0.000 0.676 0.323
E28.2 Polycystic ovarian syndrome
0.000 0.679 0.321
E27.2 Addisonian crisis
0.000 0.680 0.320
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.683 0.317
E25 Adrenogenital disorders
0.000 0.684 0.315
E34.9 Endocrine disorder, unspecified
0.000 0.686 0.314
M07.6 Other enteropathic arthropathies
0.309 0.688 0.003
M07.5 Arthropathy in ulcerative colitis
0.309 0.688 0.003
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.309 0.688 0.003
M07.2 Psoriatic spondylitis
0.309 0.688 0.003
M07.1 Arthritis mutilans
0.309 0.688 0.003
M07.0 Distal interphalangeal psoriatic arthropathy
0.309 0.688 0.003
E67.8 Other specified hyperalimentation
0.000 0.690 0.310
E67.3 Hypervitaminosis D
0.000 0.690 0.310
E67.2 Megavitamin-B6 syndrome
0.000 0.690 0.310
E67.1 Hypercarotenaemia
0.000 0.690 0.310
E67.0 Hypervitaminosis A
0.000 0.690 0.310
E16.1 Other hypoglycaemia
0.000 0.692 0.308
E34.5 Androgen resistance syndrome
0.000 0.699 0.301
E34.4 Constitutional tall stature
0.000 0.699 0.301
E34.3 Short stature, not elsewhere classified
0.000 0.699 0.301
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.699 0.301
E34.1 Other hypersecretion of intestinal hormones
0.000 0.699 0.301
E29.9 Testicular dysfunction, unspecified
0.000 0.704 0.296
E29.8 Other testicular dysfunction
0.000 0.704 0.296
E29.0 Testicular hyperfunction
0.000 0.704 0.296
E66.1 Drug-induced obesity
0.000 0.705 0.295
K90.8 Other intestinal malabsorption
0.000 0.710 0.290
E20.9 Hypoparathyroidism, unspecified
0.000 0.713 0.287
E34.0 Carcinoid syndrome
0.000 0.715 0.285
E20.8 Other hypoparathyroidism
0.000 0.721 0.279
E20.1 Pseudohypoparathyroidism
0.000 0.721 0.279
E20.0 Idiopathic hypoparathyroidism
0.000 0.721 0.279
E26.0 Primary hyperaldosteronism
0.000 0.724 0.276
E26.9 Hyperaldosteronism, unspecified
0.000 0.725 0.275
E26.8 Other hyperaldosteronism
0.000 0.725 0.275
E26.1 Secondary hyperaldosteronism
0.000 0.725 0.275
K90.3 Pancreatic steatorrhoea
0.000 0.726 0.274
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.726 0.274
K90.1 Tropical sprue
0.000 0.726 0.274
E30.9 Disorder of puberty, unspecified
0.000 0.726 0.273
E30.8 Other disorders of puberty
0.000 0.726 0.273
E30.1 Precocious puberty
0.000 0.726 0.273
E30.0 Delayed puberty
0.000 0.726 0.273
E31.9 Polyglandular dysfunction, unspecified
0.000 0.726 0.273
E31.8 Other polyglandular dysfunction
0.000 0.726 0.273
E31.1 Polyglandular hyperfunction
0.000 0.726 0.273
E31.0 Autoimmune polyglandular failure
0.000 0.726 0.273
E32.9 Disease of thymus, unspecified
0.000 0.726 0.273
E32.8 Other diseases of thymus
0.000 0.726 0.273
E32.1 Abscess of thymus
0.000 0.726 0.273
E32.0 Persistent hyperplasia of thymus
0.000 0.726 0.273
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.726 0.273
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.726 0.273
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.726 0.273
E22.1 Hyperprolactinaemia
0.000 0.730 0.270
E22.0 Acromegaly and pituitary gigantism
0.000 0.737 0.263
E44.1 Mild protein-energy malnutrition
0.001 0.742 0.258
E44.0 Moderate protein-energy malnutrition
0.001 0.742 0.258
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.747 0.253
E22.8 Other hyperfunction of pituitary gland
0.000 0.747 0.253
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.748 0.252
E24 Cushing's syndrome
0.001 0.749 0.251
K90.9 Intestinal malabsorption, unspecified
0.000 0.751 0.249
E04.8 Other specified non-toxic goitre
0.000 0.754 0.245
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.763 0.236
E66.0 Obesity due to excess calories
0.000 0.765 0.235
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.768 0.231
E04.0 Non-toxic diffuse goitre
0.000 0.771 0.229
E25.9 Adrenogenital disorder, unspecified
0.000 0.773 0.226
E25.8 Other adrenogenital disorders
0.000 0.773 0.226
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.222 0.776 0.002
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.222 0.776 0.002
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.222 0.776 0.002
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.222 0.776 0.002
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.222 0.776 0.002
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.222 0.776 0.002
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.222 0.776 0.002
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.222 0.776 0.002
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.222 0.776 0.002
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.222 0.776 0.002
M07.19 Arthritis mutilans (Site unspecified)
0.222 0.776 0.002
M07.18 Arthritis mutilans (Other)
0.222 0.776 0.002
M07.17 Arthritis mutilans (Ankle and foot)
0.222 0.776 0.002
M07.16 Arthritis mutilans (Lower leg)
0.222 0.776 0.002
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.222 0.776 0.002
M07.14 Arthritis mutilans (Hand)
0.222 0.776 0.002
M07.13 Arthritis mutilans (Forearm)
0.222 0.776 0.002
M07.12 Arthritis mutilans (Upper arm)
0.222 0.776 0.002
M07.11 Arthritis mutilans (Shoulder region)
0.222 0.776 0.002
M07.10 Arthritis mutilans (Multiple sites)
0.222 0.776 0.002
M07.29 Psoriatic spondylitis (Site unspecified)
0.222 0.776 0.002
M07.28 Psoriatic spondylitis (Other)
0.222 0.776 0.002
M07.27 Psoriatic spondylitis (Ankle and foot)
0.222 0.776 0.002
M07.26 Psoriatic spondylitis (Lower leg)
0.222 0.776 0.002
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.222 0.776 0.002
M07.24 Psoriatic spondylitis (Hand)
0.222 0.776 0.002
M07.23 Psoriatic spondylitis (Forearm)
0.222 0.776 0.002
M07.22 Psoriatic spondylitis (Upper arm)
0.222 0.776 0.002
M07.21 Psoriatic spondylitis (Shoulder region)
0.222 0.776 0.002
M07.20 Psoriatic spondylitis (Multiple sites)
0.222 0.776 0.002
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.222 0.776 0.002
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.222 0.776 0.002
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.222 0.776 0.002
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.222 0.776 0.002
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.222 0.776 0.002
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.222 0.776 0.002
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.222 0.776 0.002
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.222 0.776 0.002
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.222 0.776 0.002
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.222 0.776 0.002
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.222 0.776 0.002
M07.58 Arthropathy in ulcerative colitis (Other)
0.222 0.776 0.002
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.222 0.776 0.002
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.222 0.776 0.002
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.222 0.776 0.002
M07.54 Arthropathy in ulcerative colitis (Hand)
0.222 0.776 0.002
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.222 0.776 0.002
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.222 0.776 0.002
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.222 0.776 0.002
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.222 0.776 0.002
M07.69 Other enteropathic arthropathies (Site unspecified)
0.222 0.776 0.002
M07.68 Other enteropathic arthropathies (Other)
0.222 0.776 0.002
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.222 0.776 0.002
M07.66 Other enteropathic arthropathies (Lower leg)
0.222 0.776 0.002
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.222 0.776 0.002
M07.64 Other enteropathic arthropathies (Hand)
0.222 0.776 0.002
M07.63 Other enteropathic arthropathies (Forearm)
0.222 0.776 0.002
M07.62 Other enteropathic arthropathies (Upper arm)
0.222 0.776 0.002
M07.61 Other enteropathic arthropathies (Shoulder region)
0.222 0.776 0.002
M07.60 Other enteropathic arthropathies (Multiple sites)
0.222 0.776 0.002
E27.9 Disorder of adrenal gland, unspecified
0.001 0.796 0.204
E04.1 Non-toxic single thyroid nodule
0.000 0.799 0.201
L40-L45 Papulosquamous disorders
0.199 0.800 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.803 0.196
E04.9 Non-toxic goitre, unspecified
0.000 0.818 0.182
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.819 0.181
E24.8 Other Cushing's syndrome
0.001 0.820 0.180
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.820 0.180
E24.3 Ectopic ACTH syndrome
0.001 0.820 0.180
E24.2 Drug-induced Cushing's syndrome
0.001 0.820 0.180
E24.1 Nelson's syndrome
0.001 0.820 0.180
E04.2 Non-toxic multinodular goitre
0.000 0.825 0.175
E13.9 Without complications
0.001 0.831 0.167
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.837 0.162
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.839 0.160
E46 Unspecified protein-energy malnutrition
0.002 0.845 0.154
L44 Other papulosquamous disorders
0.143 0.857 0.000
L41 Parapsoriasis
0.143 0.857 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.143 0.857 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.859 0.141
E23.1 Drug-induced hypopituitarism
0.000 0.859 0.141
E24.9 Cushing's syndrome, unspecified
0.001 0.863 0.137
E23.2 Diabetes insipidus
0.000 0.866 0.134
M35.3 Polymyalgia rheumatica
0.000 0.866 0.134
J47 Bronchiectasis
0.000 0.869 0.131
E23.6 Other disorders of pituitary gland
0.000 0.870 0.130
E24.0 Pituitary-dependent Cushing's disease
0.001 0.874 0.125
E23.7 Disorder of pituitary gland, unspecified
0.000 0.877 0.122
L42 Pityriasis rosea
0.122 0.877 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.883 0.117
E21.2 Other hyperparathyroidism
0.000 0.883 0.117
E70-E90 Metabolic disorders
0.000 0.886 0.114
E11 Non-insulin-dependent diabetes mellitus
0.000 0.889 0.111
M35 Other systemic involvement of connective tissue
0.000 0.893 0.107
E11.3 With ophthalmic complications
0.000 0.896 0.104
L41.9 Parapsoriasis, unspecified
0.103 0.897 0.000
L41.8 Other parapsoriasis
0.103 0.897 0.000
L41.5 Retiform parapsoriasis
0.103 0.897 0.000
L41.4 Large plaque parapsoriasis
0.103 0.897 0.000
L41.3 Small plaque parapsoriasis
0.103 0.897 0.000
L41.2 Lymphomatoid papulosis
0.103 0.897 0.000
L41.1 Pityriasis lichenoides chronica
0.103 0.897 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.103 0.897 0.000
L44.9 Papulosquamous disorder, unspecified
0.103 0.897 0.000
L44.8 Other specified papulosquamous disorders
0.103 0.897 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.103 0.897 0.000
L44.3 Lichen ruber moniliformis
0.103 0.897 0.000
L44.2 Lichen striatus
0.103 0.897 0.000
L44.1 Lichen nitidus
0.103 0.897 0.000
L44.0 Pityriasis rubra pilaris
0.103 0.897 0.000
E73 Lactose intolerance
0.000 0.898 0.102
M35.0 Sicca syndrome [Sjogren]
0.000 0.900 0.100
E83 Disorders of mineral metabolism
0.000 0.901 0.099
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.903 0.097
E21.0 Primary hyperparathyroidism
0.000 0.905 0.095
E73.9 Lactose intolerance, unspecified
0.000 0.907 0.093
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.907 0.092
E85 Amyloidosis
0.000 0.908 0.092
M35.1 Other overlap syndromes
0.000 0.910 0.090
E83.4 Disorders of magnesium metabolism
0.000 0.910 0.090
E74 Other disorders of carbohydrate metabolism
0.000 0.913 0.087
E83.3 Disorders of phosphorus metabolism
0.000 0.913 0.087
E84 Cystic fibrosis
0.000 0.918 0.082
E79 Disorders of purine and pyrimidine metabolism
0.000 0.918 0.082
E77 Disorders of glycoprotein metabolism
0.000 0.918 0.082
E76 Disorders of glycosaminoglycan metabolism
0.000 0.918 0.082
E72 Other disorders of amino-acid metabolism
0.000 0.918 0.082
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.918 0.082
E70 Disorders of aromatic amino-acid metabolism
0.000 0.918 0.082
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.918 0.082
E11.8 With unspecified complications
0.000 0.918 0.082
L43 Lichen planus
0.080 0.920 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.920 0.080
E11.7 With multiple complications
0.000 0.920 0.080
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.922 0.078
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.923 0.077
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.923 0.077
M35.5 Multifocal fibrosclerosis
0.000 0.923 0.077
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.923 0.077
M35.2 Behcet's disease
0.000 0.923 0.077
E85.9 Amyloidosis, unspecified
0.000 0.926 0.074
E73.8 Other lactose intolerance
0.000 0.927 0.073
E73.1 Secondary lactase deficiency
0.000 0.927 0.073
E73.0 Congenital lactase deficiency
0.000 0.927 0.073
E11.5 With peripheral circulatory complications
0.000 0.927 0.073
M35.7 Hypermobility syndrome
0.000 0.928 0.072
E11.0 With coma
0.000 0.928 0.072
M35.8 Other specified systemic involvement of connective tissue
0.000 0.928 0.072
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.929 0.071
E83.8 Other disorders of mineral metabolism
0.000 0.929 0.071
E83.2 Disorders of zinc metabolism
0.000 0.929 0.071
E83.0 Disorders of copper metabolism
0.000 0.929 0.071
E85.4 Organ-limited amyloidosis
0.000 0.931 0.069
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.932 0.068
E85.8 Other amyloidosis
0.000 0.934 0.066
E85.3 Secondary systemic amyloidosis
0.000 0.934 0.066
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.934 0.066
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.934 0.066
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.934 0.066
E23.0 Hypopituitarism
0.001 0.935 0.064
E11.1 With ketoacidosis
0.000 0.937 0.063
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.937 0.063
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.937 0.063
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.937 0.063
E74.2 Disorders of galactose metabolism
0.000 0.937 0.063
E74.1 Disorders of fructose metabolism
0.000 0.937 0.063
E74.0 Glycogen storage disease
0.000 0.937 0.063
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.940 0.059
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.941 0.059
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.941 0.059
E70.3 Albinism
0.000 0.941 0.059
E70.2 Disorders of tyrosine metabolism
0.000 0.941 0.059
E70.1 Other hyperphenylalaninaemias
0.000 0.941 0.059
E70.0 Classical phenylketonuria
0.000 0.941 0.059
E71.3 Disorders of fatty-acid metabolism
0.000 0.941 0.059
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.941 0.059
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.941 0.059
E71.0 Maple-syrup-urine disease
0.000 0.941 0.059
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.941 0.059
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.941 0.059
E72.5 Disorders of glycine metabolism
0.000 0.941 0.059
E72.4 Disorders of ornithine metabolism
0.000 0.941 0.059
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.941 0.059
E72.2 Disorders of urea cycle metabolism
0.000 0.941 0.059
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.941 0.059
E72.0 Disorders of amino-acid transport
0.000 0.941 0.059
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.941 0.059
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.941 0.059
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.941 0.059
E76.2 Other mucopolysaccharidoses
0.000 0.941 0.059
E76.1 Mucopolysaccharidosis, type II
0.000 0.941 0.059
E76.0 Mucopolysaccharidosis, type I
0.000 0.941 0.059
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.941 0.059
E77.8 Other disorders of glycoprotein metabolism
0.000 0.941 0.059
E77.1 Defects in glycoprotein degradation
0.000 0.941 0.059
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.941 0.059
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.941 0.059
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.941 0.059
E79.1 Lesch-Nyhan syndrome
0.000 0.941 0.059
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.941 0.059
E84.9 Cystic fibrosis, unspecified
0.000 0.941 0.059
E84.8 Cystic fibrosis with other manifestations
0.000 0.941 0.059
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.941 0.059
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.941 0.059
L43.3 Subacute (active) lichen planus
0.057 0.942 0.000
L43.2 Lichenoid drug reaction
0.057 0.942 0.000
L43.1 Bullous lichen planus
0.057 0.942 0.000
L43.0 Hypertrophic lichen planus
0.057 0.942 0.000
E75.6 Lipid storage disorder, unspecified
0.000 0.944 0.056
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.944 0.056
E75.3 Sphingolipidosis, unspecified
0.000 0.944 0.056
E75.2 Other sphingolipidosis
0.000 0.944 0.056
E75.1 Other gangliosidosis
0.000 0.944 0.056
E75.0 GM2 gangliosidosis
0.000 0.944 0.056
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.000 0.944 0.056

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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