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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3828905
log Bayes Factor = 64.4863
Chromosome 6   position 31,464,902  (GRCh37) Explore rs3828905 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.997 0.003 0.000
R31 Unspecified haematuria
0.997 0.003 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.006 0.994
E10-E14 Diabetes mellitus
0.000 0.007 0.993
E05.9 Thyrotoxicosis, unspecified
0.000 0.008 0.992
E00-E07 Disorders of thyroid gland
0.000 0.012 0.988
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.012 0.988
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.017 0.983
E10.2 With renal complications
0.000 0.024 0.976
E10.9 Without complications
0.000 0.029 0.971
G35 Multiple sclerosis
0.000 0.041 0.959
E10.3 With ophthalmic complications
0.000 0.041 0.959
M45.X2 Ankylosing spondylitis (Cervical region)
0.951 0.049 0.000
E10.1 With ketoacidosis
0.000 0.068 0.932
K90 Intestinal malabsorption
0.000 0.070 0.930
E10.4 With neurological complications
0.000 0.082 0.918
K90.9 Intestinal malabsorption, unspecified
0.000 0.089 0.911
E20-E35 Disorders of other endocrine glands
0.000 0.102 0.898
E27 Other disorders of adrenal gland
0.000 0.107 0.893
E50-E64 Other nutritional deficiencies
0.000 0.114 0.886
E27.1 Primary adrenocortical insufficiency
0.000 0.126 0.874
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.130 0.870
E10.8 With unspecified complications
0.000 0.137 0.863
I25 Chronic ischaemic heart disease
0.859 0.141 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.145 0.855
I20-I25 Ischaemic heart diseases
0.854 0.146 0.000
E05.8 Other thyrotoxicosis
0.000 0.146 0.854
G37 Other demyelinating diseases of central nervous system
0.000 0.147 0.853
I20 Angina pectoris
0.853 0.147 0.000
I25.1 Atherosclerotic heart disease
0.850 0.150 0.000
I20.0 Unstable angina
0.847 0.153 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.155 0.845
M45.X6 Ankylosing spondylitis (Lumbar region)
0.840 0.160 0.000
E11.5 With peripheral circulatory complications
0.000 0.175 0.825
I24 Other acute ischaemic heart diseases
0.815 0.185 0.000
E10.5 With peripheral circulatory complications
0.000 0.185 0.815
E10.6 With other specified complications
0.000 0.189 0.811
E06 Thyroiditis
0.000 0.193 0.807
I20.9 Angina pectoris, unspecified
0.788 0.212 0.000
E53 Deficiency of other B group vitamins
0.000 0.213 0.787
I25.9 Chronic ischaemic heart disease, unspecified
0.786 0.214 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.216 0.784
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.773 0.227 0.000
E61 Deficiency of other nutrient elements
0.000 0.228 0.772
I25.5 Ischaemic cardiomyopathy
0.770 0.230 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.233 0.767
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.252 0.748
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.261 0.739
I20.1 Angina pectoris with documented spasm
0.737 0.263 0.000
E34 Other endocrine disorders
0.000 0.271 0.729
E27.2 Addisonian crisis
0.000 0.279 0.721
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.280 0.720
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E10.7 With multiple complications
0.000 0.284 0.716
E20 Hypoparathyroidism
0.000 0.285 0.715
E06.9 Thyroiditis, unspecified
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.287 0.713
E12 Malnutrition-related diabetes mellitus
0.000 0.288 0.712
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.289 0.711
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.291 0.708
E00 Congenital iodine-deficiency syndrome
0.000 0.291 0.708
I24.8 Other forms of acute ischaemic heart disease
0.709 0.291 0.000
E14 Unspecified diabetes mellitus
0.000 0.299 0.701
I25.2 Old myocardial infarction
0.700 0.300 0.000
E11.4 With neurological complications
0.000 0.302 0.698
E07 Other disorders of thyroid
0.000 0.310 0.690
E53.8 Deficiency of other specified B group vitamins
0.000 0.311 0.689
E40-E46 Malnutrition
0.000 0.317 0.683
I23 Certain current complications following acute myocardial infarction
0.682 0.318 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.682 0.318 0.000
E11.6 With other specified complications
0.000 0.329 0.671
E11.3 With ophthalmic complications
0.000 0.331 0.669
K90.3 Pancreatic steatorrhoea
0.000 0.333 0.667
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.333 0.667
K90.1 Tropical sprue
0.000 0.333 0.667
E61.1 Iron deficiency
0.000 0.341 0.659
K90.8 Other intestinal malabsorption
0.000 0.344 0.656
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.356 0.644
E32 Diseases of thymus
0.000 0.356 0.644
E31 Polyglandular dysfunction
0.000 0.356 0.644
E30 Disorders of puberty, not elsewhere classified
0.000 0.356 0.644
I25.4 Coronary artery aneurysm
0.641 0.359 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.360 0.640
E27.0 Other adrenocortical overactivity
0.000 0.360 0.640
E51 Thiamine deficiency
0.000 0.360 0.639
E25 Adrenogenital disorders
0.000 0.361 0.639
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.365 0.635
E63 Other nutritional deficiencies
0.000 0.365 0.635
E50 Vitamin A deficiency
0.000 0.365 0.635
E60 Dietary zinc deficiency
0.000 0.365 0.635
E59 Dietary selenium deficiency
0.000 0.365 0.635
E54 Ascorbic acid deficiency
0.000 0.365 0.635
E52 Niacin deficiency [pellagra]
0.000 0.365 0.635
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.371 0.629
E53.9 Vitamin B deficiency, unspecified
0.000 0.373 0.627
I25.6 Silent myocardial ischaemia
0.627 0.373 0.000
E10.0 With coma
0.000 0.380 0.620
E11.7 With multiple complications
0.000 0.387 0.613
E61.2 Magnesium deficiency
0.000 0.388 0.612
G37.5 Concentric sclerosis [Balo]
0.000 0.388 0.611
G37.4 Subacute necrotising myelitis
0.000 0.388 0.611
G37.2 Central pontine myelinolysis
0.000 0.388 0.611
G37.1 Central demyelination of corpus callosum
0.000 0.388 0.611
G37.0 Diffuse sclerosis
0.000 0.388 0.611
E56 Other vitamin deficiencies
0.000 0.391 0.608
G36 Other acute disseminated demyelination
0.000 0.392 0.608
E11.1 With ketoacidosis
0.000 0.397 0.603
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.400 0.600
E11.8 With unspecified complications
0.000 0.401 0.599
E34.9 Endocrine disorder, unspecified
0.000 0.404 0.596
E55 Vitamin D deficiency
0.000 0.412 0.588
I24.9 Acute ischaemic heart disease, unspecified
0.584 0.416 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.416 0.584
E14.3 With ophthalmic complications
0.000 0.417 0.583
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.421 0.579
E06.4 Drug-induced thyroiditis
0.000 0.421 0.578
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.421 0.578
E06.1 Subacute thyroiditis
0.000 0.421 0.578
E06.0 Acute thyroiditis
0.000 0.421 0.578
E58 Dietary calcium deficiency
0.000 0.426 0.574
E53.1 Pyridoxine deficiency
0.000 0.435 0.564
E53.0 Riboflavin deficiency
0.000 0.435 0.564
E14.1 With ketoacidosis
0.000 0.439 0.561
I23.8 Other current complications following acute myocardial infarction
0.559 0.441 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.442 0.558
E61.9 Deficiency of nutrient element, unspecified
0.000 0.447 0.553
E61.8 Deficiency of other specified nutrient elements
0.000 0.447 0.553
E61.7 Deficiency of multiple nutrient elements
0.000 0.447 0.553
E61.6 Vanadium deficiency
0.000 0.447 0.553
E61.5 Molybdenum deficiency
0.000 0.447 0.553
E61.4 Chromium deficiency
0.000 0.447 0.553
E61.3 Manganese deficiency
0.000 0.447 0.553
E61.0 Copper deficiency
0.000 0.447 0.553
E21.0 Primary hyperparathyroidism
0.000 0.448 0.552
E14.5 With peripheral circulatory complications
0.000 0.450 0.550
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.450 0.550
E29 Testicular dysfunction
0.000 0.451 0.549
E27.9 Disorder of adrenal gland, unspecified
0.000 0.451 0.548
E13 Other specified diabetes mellitus
0.000 0.454 0.546
I25.3 Aneurysm of heart
0.545 0.455 0.000
E06.5 Other chronic thyroiditis
0.000 0.458 0.542
E34.8 Other specified endocrine disorders
0.000 0.463 0.537
E07.9 Disorder of thyroid, unspecified
0.000 0.464 0.536
E24 Cushing's syndrome
0.000 0.469 0.531
E26 Hyperaldosteronism
0.000 0.470 0.530
E06.3 Autoimmune thyroiditis
0.000 0.471 0.529
E34.0 Carcinoid syndrome
0.000 0.472 0.528
E34.5 Androgen resistance syndrome
0.000 0.477 0.523
E34.4 Constitutional tall stature
0.000 0.477 0.523
E34.3 Short stature, not elsewhere classified
0.000 0.477 0.523
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.477 0.523
E34.1 Other hypersecretion of intestinal hormones
0.000 0.477 0.523
E14.6 With other specified complications
0.000 0.478 0.521
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.481 0.519
E14.8 With unspecified complications
0.000 0.482 0.518
E20.8 Other hypoparathyroidism
0.000 0.487 0.513
E20.1 Pseudohypoparathyroidism
0.000 0.487 0.513
E20.0 Idiopathic hypoparathyroidism
0.000 0.487 0.513
E12.9 Without complications
0.000 0.489 0.510
E12.8 With unspecified complications
0.000 0.489 0.510
E12.7 With multiple complications
0.000 0.489 0.510
E12.6 With other specified complications
0.000 0.489 0.510
E12.5 With peripheral circulatory complications
0.000 0.489 0.510
E12.4 With neurological complications
0.000 0.489 0.510
E12.3 With ophthalmic complications
0.000 0.489 0.510
E12.2 With renal complications
0.000 0.489 0.510
E12.1 With ketoacidosis
0.000 0.489 0.510
E12.0 With coma
0.000 0.489 0.510
E21.4 Other specified disorders of parathyroid gland
0.000 0.490 0.510
E11.2 With renal complications
0.000 0.490 0.510
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.492 0.508
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.492 0.508
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.492 0.508
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.492 0.508
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.492 0.508
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.492 0.508
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.492 0.508
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.492 0.508
E14.7 With multiple complications
0.000 0.497 0.503
E14.2 Withrenal complications
0.000 0.497 0.503
E14.0 With coma
0.000 0.497 0.503
E07.1 Dyshormogenetic goitre
0.000 0.505 0.495
E07.0 Hypersecretion of calcitonin
0.000 0.505 0.495
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.510 0.490
E45 Retarded development following protein-energy malnutrition
0.000 0.510 0.490
E43 Unspecified severe protein-energy malnutrition
0.000 0.510 0.490
E42 Marasmic kwashiorkor
0.000 0.510 0.490
E41 Nutritional marasmus
0.000 0.510 0.490
E40 Kwashiorkor
0.000 0.510 0.490
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.489 0.511 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.489 0.511 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.489 0.511 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.489 0.511 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.489 0.511 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.489 0.511 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.489 0.511 0.000
E21.2 Other hyperparathyroidism
0.000 0.513 0.487
I25.0 Atherosclerotic cardiovascular disease, so described
0.478 0.521 0.000
I24.1 Dressler's syndrome
0.478 0.521 0.000
E14.4 With neurological complications
0.000 0.526 0.474
E46 Unspecified protein-energy malnutrition
0.000 0.535 0.464
E51.2 Wernicke's encephalopathy
0.000 0.537 0.463
E30.9 Disorder of puberty, unspecified
0.000 0.538 0.462
E30.8 Other disorders of puberty
0.000 0.538 0.462
E30.1 Precocious puberty
0.000 0.538 0.462
E30.0 Delayed puberty
0.000 0.538 0.462
E31.9 Polyglandular dysfunction, unspecified
0.000 0.538 0.462
E31.8 Other polyglandular dysfunction
0.000 0.538 0.462
E31.1 Polyglandular hyperfunction
0.000 0.538 0.462
E31.0 Autoimmune polyglandular failure
0.000 0.538 0.462
E32.9 Disease of thymus, unspecified
0.000 0.538 0.462
E32.8 Other diseases of thymus
0.000 0.538 0.462
E32.1 Abscess of thymus
0.000 0.538 0.462
E32.0 Persistent hyperplasia of thymus
0.000 0.538 0.462
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.538 0.462
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.538 0.462
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.538 0.462
E51.9 Thiamine deficiency, unspecified
0.000 0.541 0.458
E51.8 Other manifestations of thiamine deficiency
0.000 0.541 0.458
E51.1 Beriberi
0.000 0.541 0.458
E25.9 Adrenogenital disorder, unspecified
0.000 0.542 0.458
E25.8 Other adrenogenital disorders
0.000 0.542 0.458
E50.9 Vitamin A deficiency, unspecified
0.000 0.544 0.455
E50.8 Other manifestations of vitamin A deficiency
0.000 0.544 0.455
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.544 0.455
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.544 0.455
E50.5 Vitamin A deficiency with night blindness
0.000 0.544 0.455
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.544 0.455
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.544 0.455
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.544 0.455
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.544 0.455
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.544 0.455
E63.9 Nutritional deficiency, unspecified
0.000 0.544 0.455
E63.8 Other specified nutritional deficiencies
0.000 0.544 0.455
E63.1 Imbalance of constituents of food intake
0.000 0.544 0.455
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.544 0.455
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.544 0.455
E64.8 Sequelae of other nutritional deficiencies
0.000 0.544 0.455
E64.3 Sequelae of rickets
0.000 0.544 0.455
E64.2 Sequelae of vitamin C deficiency
0.000 0.544 0.455
E64.1 Sequelae of vitamin A deficiency
0.000 0.544 0.455
E64.0 Sequelae of protein-energy malnutrition
0.000 0.544 0.455
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.547 0.453
I22 Subsequent myocardial infarction
0.443 0.557 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.564 0.436
E56.8 Deficiency of other vitamins
0.000 0.564 0.436
E56.0 Deficiency of vitamin E
0.000 0.564 0.436
G36.9 Acute disseminated demyelination, unspecified
0.000 0.564 0.436
G36.8 Other specified acute disseminated demyelination
0.000 0.564 0.436
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.564 0.436
I21 Acute myocardial infarction
0.431 0.569 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.423 0.577 0.000
E55.0 Rickets, active
0.000 0.579 0.421
E21.3 Hyperparathyroidism, unspecified
0.000 0.579 0.421
G36.0 Neuromyelitis optica [Devic]
0.000 0.579 0.421
E07.8 Other specified disorders of thyroid
0.000 0.580 0.420
R30.0 Dysuria
0.418 0.582 0.000
R30-R39 Symptoms and signs involving the urinary system
0.411 0.589 0.000
R30 Pain associated with micturition
0.410 0.590 0.000
E56.1 Deficiency of vitamin K
0.000 0.590 0.409
I22.1 Subsequent myocardial infarction of inferior wall
0.405 0.595 0.000
E28 Ovarian dysfunction
0.000 0.600 0.400
E15 Nondiabetic hypoglycaemic coma
0.000 0.606 0.394
E29.9 Testicular dysfunction, unspecified
0.000 0.606 0.394
E29.8 Other testicular dysfunction
0.000 0.606 0.394
E29.0 Testicular hyperfunction
0.000 0.606 0.394
E11.0 With coma
0.000 0.606 0.393
E13.8 With unspecified complications
0.000 0.608 0.391
E13.7 With multiple complications
0.000 0.608 0.391
E13.6 With other specified complications
0.000 0.608 0.391
E13.5 With peripheral circulatory complications
0.000 0.608 0.391
E13.4 With neurological complications
0.000 0.608 0.391
E13.2 With renal complications
0.000 0.608 0.391
E13.1 With ketoacidosis
0.000 0.608 0.391
E13.0 With coma
0.000 0.608 0.391
E13.3 With ophthalmic complications
0.000 0.609 0.391
E24.8 Other Cushing's syndrome
0.000 0.619 0.381
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.619 0.381
E24.3 Ectopic ACTH syndrome
0.000 0.619 0.381
E24.1 Nelson's syndrome
0.000 0.619 0.381
E26.8 Other hyperaldosteronism
0.000 0.620 0.380
E26.1 Secondary hyperaldosteronism
0.000 0.620 0.380
R34 Anuria and oliguria
0.378 0.622 0.000
E22 Hyperfunction of pituitary gland
0.000 0.625 0.375
E55.9 Vitamin D deficiency, unspecified
0.000 0.626 0.374
E24.0 Pituitary-dependent Cushing's disease
0.000 0.632 0.368
E26.9 Hyperaldosteronism, unspecified
0.000 0.635 0.365
E24.2 Drug-induced Cushing's syndrome
0.000 0.646 0.354
E44.1 Mild protein-energy malnutrition
0.000 0.649 0.351
E44.0 Moderate protein-energy malnutrition
0.000 0.649 0.351
E65-E68 Obesity and other hyperalimentation
0.000 0.664 0.336
E24.9 Cushing's syndrome, unspecified
0.000 0.675 0.325
I21.X Presumed acute myicardial infaction (unconfirmed)
0.309 0.691 0.000
I21.9 Acute myocardial infarction, unspecified
0.305 0.695 0.000
E29.1 Testicular hypofunction
0.000 0.701 0.299
R30.1 Vesical tenesmus
0.298 0.702 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.703 0.297
E03 Other hypothyroidism
0.001 0.707 0.291
E26.0 Primary hyperaldosteronism
0.000 0.709 0.291
E28.9 Ovarian dysfunction, unspecified
0.000 0.713 0.287
E28.8 Other ovarian dysfunction
0.000 0.713 0.287
E28.1 Androgen excess
0.000 0.713 0.287
E28.0 Oestrogen excess
0.000 0.713 0.287
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.731 0.269
E22.8 Other hyperfunction of pituitary gland
0.000 0.731 0.269
E28.3 Primary ovarian failure
0.000 0.742 0.257
R36 Urethral discharge
0.252 0.748 0.000
I22.8 Subsequent myocardial infarction of other sites
0.248 0.752 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.242 0.758 0.000
E67 Other hyperalimentation
0.000 0.759 0.241
E68 Sequelae of hyperalimentation
0.000 0.759 0.241
E22.1 Hyperprolactinaemia
0.000 0.764 0.236
E16 Other disorders of pancreatic internal secretion
0.000 0.764 0.236
M25.55 Pain in joint (Pelvic region and thigh)
0.000 0.769 0.231
E13.9 Without complications
0.000 0.773 0.227
E23.7 Disorder of pituitary gland, unspecified
0.000 0.775 0.225
M25.54 Pain in joint (Hand)
0.000 0.782 0.218
M25.5 Pain in joint
0.000 0.782 0.218
I20.8 Other forms of angina pectoris
0.218 0.782 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.787 0.213
E23.1 Drug-induced hypopituitarism
0.000 0.787 0.213
E03.5 Myxoedema coma
0.001 0.790 0.209
E03.4 Atrophy of thyroid (acquired)
0.001 0.790 0.209
E03.3 Postinfectious hypothyroidism
0.001 0.790 0.209
E03.0 Congenital hypothyroidism with diffuse goitre
0.001 0.790 0.209
E22.0 Acromegaly and pituitary gigantism
0.000 0.790 0.210
E03.1 Congenital hypothyroidism without goitre
0.001 0.794 0.205
I22.0 Subsequent myocardial infarction of anterior wall
0.194 0.805 0.000
E03.8 Other specified hypothyroidism
0.001 0.807 0.193
M25 Other joint disorders, not elsewhere classified
0.000 0.807 0.193
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.809 0.191
M25.6 Stiffness of joint, not elsewhere classified
0.000 0.809 0.191
R30.9 Painful micturition, unspecified
0.190 0.810 0.000
M25.53 Pain in joint (Forearm)
0.000 0.813 0.187
M25.7 Osteophyte
0.000 0.814 0.186
M25.58 Pain in joint (Other)
0.000 0.816 0.184
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.000 0.817 0.183
E23.2 Diabetes insipidus
0.000 0.817 0.183
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.001 0.820 0.179
E67.8 Other specified hyperalimentation
0.000 0.827 0.173
E67.3 Hypervitaminosis D
0.000 0.827 0.173
E67.2 Megavitamin-B6 syndrome
0.000 0.827 0.173
E67.1 Hypercarotenaemia
0.000 0.827 0.173
E67.0 Hypervitaminosis A
0.000 0.827 0.173
M25.71 Osteophyte (Shoulder region)
0.000 0.829 0.171
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.831 0.169
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.831 0.169
E16.4 Abnormal secretion of gastrin
0.000 0.831 0.169
E16.3 Increased secretion of glucagon
0.000 0.831 0.169
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.000 0.832 0.168
M25.9 Joint disorder, unspecified
0.000 0.837 0.163
M25.77 Osteophyte (Ankle and foot)
0.000 0.840 0.160
E11.9 Without complications
0.000 0.841 0.159
M25.72 Osteophyte (Upper arm)
0.000 0.841 0.159
E65 Localised adiposity
0.000 0.842 0.158
E04 Other non-toxic goitre
0.000 0.843 0.157
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.000 0.844 0.156
M25.76 Osteophyte (Lower leg)
0.000 0.848 0.152
M25.74 Osteophyte (Hand)
0.000 0.851 0.149
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.000 0.853 0.147
E16.1 Other hypoglycaemia
0.000 0.854 0.146
M25.50 Pain in joint (Multiple sites)
0.000 0.854 0.146
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.000 0.855 0.145
M25.96 Joint disorder, unspecified (Lower leg)
0.000 0.855 0.145
M25.52 Pain in joint (Upper arm)
0.000 0.855 0.145
M25.0 Haemarthrosis
0.000 0.857 0.143
M25.73 Osteophyte (Forearm)
0.000 0.857 0.143
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.857 0.142
I21.1 Acute transmural myocardial infarction of inferior wall
0.141 0.859 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.000 0.860 0.140
M25.2 Flail joint
0.000 0.861 0.139
M25.1 Fistula of joint
0.000 0.861 0.139
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.000 0.863 0.137
I22.9 Subsequent myocardial infarction of unspecified site
0.137 0.863 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.000 0.865 0.135
M25.57 Pain in joint (Ankle and foot)
0.000 0.865 0.135
M25.70 Osteophyte (Multiple sites)
0.000 0.866 0.134
M25.79 Osteophyte (Site unspecified)
0.000 0.867 0.133
M25.91 Joint disorder, unspecified (Shoulder region)
0.000 0.869 0.131
R39 Other symptoms and signs involving the urinary system
0.129 0.871 0.000
E23.6 Other disorders of pituitary gland
0.001 0.873 0.126
M25.94 Joint disorder, unspecified (Hand)
0.000 0.876 0.124
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.000 0.877 0.123
M25.59 Pain in joint (Site unspecified)
0.000 0.877 0.123
M25.78 Osteophyte (Other)
0.000 0.881 0.119
E04.0 Non-toxic diffuse goitre
0.000 0.882 0.118
M25.98 Joint disorder, unspecified (Other)
0.000 0.883 0.117
M25.92 Joint disorder, unspecified (Upper arm)
0.000 0.883 0.117
M25.90 Joint disorder, unspecified (Multiple sites)
0.000 0.883 0.117
E28.2 Polycystic ovarian syndrome
0.001 0.883 0.116
E16.2 Hypoglycaemia, unspecified
0.000 0.883 0.117
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.885 0.115
E04.8 Other specified non-toxic goitre
0.000 0.887 0.113
E23.0 Hypopituitarism
0.000 0.887 0.113
M25.99 Joint disorder, unspecified (Site unspecified)
0.000 0.887 0.113
M25.93 Joint disorder, unspecified (Forearm)
0.000 0.888 0.112
M25.95 Joint disorder, unspecified (Pelvic region and thigh)
0.000 0.889 0.111
H20.9 Iridocyclitis, unspecified
0.108 0.892 0.000
M25.06 Haemarthrosis (Lower leg)
0.000 0.892 0.108
M25.09 Haemarthrosis (Site unspecified)
0.000 0.897 0.103
M25.08 Haemarthrosis (Other)
0.000 0.897 0.103
M25.07 Haemarthrosis (Ankle and foot)
0.000 0.897 0.103
M25.05 Haemarthrosis (Pelvic region and thigh)
0.000 0.897 0.103
M25.04 Haemarthrosis (Hand)
0.000 0.897 0.103
M25.03 Haemarthrosis (Forearm)
0.000 0.897 0.103
M25.02 Haemarthrosis (Upper arm)
0.000 0.897 0.103
M25.01 Haemarthrosis (Shoulder region)
0.000 0.897 0.103
M25.00 Haemarthrosis (Multiple sites)
0.000 0.897 0.103
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.000 0.898 0.102
I21.0 Acute transmural myocardial infarction of anterior wall
0.101 0.899 0.000
M25.19 Fistula of joint (Site unspecified)
0.000 0.900 0.100
M25.18 Fistula of joint (Other)
0.000 0.900 0.100
M25.17 Fistula of joint (Ankle and foot)
0.000 0.900 0.100
M25.16 Fistula of joint (Lower leg)
0.000 0.900 0.100
M25.15 Fistula of joint (Pelvic region and thigh)
0.000 0.900 0.100
M25.14 Fistula of joint (Hand)
0.000 0.900 0.100
M25.13 Fistula of joint (Forearm)
0.000 0.900 0.100
M25.12 Fistula of joint (Upper arm)
0.000 0.900 0.100
M25.11 Fistula of joint (Shoulder region)
0.000 0.900 0.100
M25.10 Fistula of joint (Multiple sites)
0.000 0.900 0.100
M25.29 Flail joint (Site unspecified)
0.000 0.900 0.100
M25.28 Flail joint (Other)
0.000 0.900 0.100
M25.27 Flail joint (Ankle and foot)
0.000 0.900 0.100
M25.26 Flail joint (Lower leg)
0.000 0.900 0.100
M25.25 Flail joint (Pelvic region and thigh)
0.000 0.900 0.100
M25.24 Flail joint (Hand)
0.000 0.900 0.100
M25.23 Flail joint (Forearm)
0.000 0.900 0.100
M25.22 Flail joint (Upper arm)
0.000 0.900 0.100
M25.21 Flail joint (Shoulder region)
0.000 0.900 0.100
M25.20 Flail joint (Multiple sites)
0.000 0.900 0.100
M25.97 Joint disorder, unspecified (Ankle and foot)
0.000 0.902 0.098
S02.4 Fracture of malar and maxillary bones
0.000 0.905 0.095
C71 Malignant neoplasm of brain
0.095 0.905 0.000
C71.9 Brain, unspecified
0.094 0.906 0.000
C71.2 Temporal lobe
0.094 0.906 0.000
R39.2 Extrarenal uraemia
0.093 0.907 0.000
C71.0 Cerebrum, except lobes and ventricles
0.091 0.909 0.000
R39.0 Extravasation of urine
0.086 0.913 0.000
E66 Obesity
0.000 0.914 0.086
S02 Fracture of skull and facial bones
0.000 0.919 0.081
C71.3 Parietal lobe
0.081 0.919 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.078 0.922 0.000
S06 Intracranial injury
0.000 0.923 0.077
S00-S09 Injuries to the head
0.000 0.924 0.076
M25.3 Other instability of joint
0.000 0.928 0.072
S06.3 Focal brain injury
0.000 0.929 0.071
S02.6 Fracture of mandible
0.000 0.929 0.071
S06.0 Concussion
0.000 0.931 0.069
K90-K93 Other diseases of the digestive system
0.000 0.931 0.069
M25.8 Other specified joint disorders
0.000 0.931 0.069
S02.41 Fracture of malar and maxillary bones (open)
0.000 0.931 0.069
C71.7 Brain stem
0.069 0.931 0.000
C71.6 Cerebellum
0.069 0.931 0.000
C71.5 Cerebral ventricle
0.069 0.931 0.000
C71.8 Overlapping lesion of brain
0.068 0.932 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.932 0.068
S06.2 Diffuse brain injury
0.000 0.933 0.066
S06.5 Traumatic subdural haemorrhage
0.000 0.934 0.066
S00 Superficial injury of head
0.000 0.935 0.065
S05 Injury of eye and orbit
0.000 0.935 0.064
C71.4 Occipital lobe
0.064 0.936 0.000
S06.00 Concussion (without open intracranial wound)
0.000 0.936 0.064
S02.60 Fracture of mandible (closed)
0.000 0.936 0.064
R32 Unspecified urinary incontinence
0.063 0.937 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.937 0.063
S00.1 Contusion of eyelid and periocular area
0.000 0.938 0.062
E66.1 Drug-induced obesity
0.000 0.938 0.062
S02.9 Fracture of skull and facial bones, part unspecified
0.000 0.939 0.061
M45-M49 Spondylopathies
0.061 0.939 0.000
S09 Other and unspecified injuries of head
0.000 0.940 0.060
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.941 0.059
S09.8 Other specified injuries of head
0.000 0.941 0.059
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.942 0.058
I21.4 Acute subendocardial myocardial infarction
0.058 0.942 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.943 0.057
S06.4 Epidural haemorrhage
0.000 0.943 0.057
N93.8 Other specified abnormal uterine and vaginal bleeding
0.000 0.944 0.056
E04.2 Non-toxic multinodular goitre
0.000 0.944 0.056
S02.5 Fracture of tooth
0.000 0.944 0.055
S05.8 Other injuries of eye and orbit
0.000 0.945 0.055
S06.7 Intracranial injury with prolonged coma
0.000 0.945 0.055
C71.1 Frontal lobe
0.055 0.945 0.000
S02.7 Multiple fractures involving skull and facial bones
0.000 0.945 0.055
S02.3 Fracture of orbital floor
0.000 0.945 0.055
S05.9 Injury of eye and orbit, part unspecified
0.000 0.945 0.055
S02.0 Fracture of vault of skull
0.000 0.945 0.054
S08 Traumatic amputation of part of head
0.000 0.945 0.054
S07 Crushing injury of head
0.000 0.945 0.054

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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