TreeWAS – Variant ID: rs3849942

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.649	0.351	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.649	0.351	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.634	0.366	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.598	0.402	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.597	0.403	0.000
T39.1 4-Aminophenol derivatives	0.583	0.417	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.581	0.419	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.581	0.419	0.000
T36 Poisoning by systemic antibiotics	0.578	0.422	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.569	0.431	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.562	0.438	0.000
T40.2 Other opioids	0.548	0.452	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.541	0.459	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.524	0.476	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.505	0.495	0.000
T36.0 Penicillins	0.500	0.500	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.498	0.502	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.497	0.503	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.493	0.507	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.492	0.508	0.000
T43.2 Other and unspecified antidepressants	0.479	0.521	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.477	0.523	0.000
T39.0 Salicylates	0.473	0.527	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.470	0.530	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.467	0.533	0.000
T42.0 Hydantoin derivatives	0.466	0.534	0.000
T39.4 Antirheumatics, not elsewhere classified	0.465	0.534	0.000
T39.2 Pyrazolone derivatives	0.465	0.534	0.000
T38.1 Thyroid hormones and substitutes	0.462	0.538	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.460	0.540	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.459	0.540	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.459	0.541	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.455	0.545	0.000
T42.1 Iminostilbenes	0.455	0.545	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.450	0.550	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.449	0.551	0.000
T38.0 Glucocorticoids and synthetic analogues	0.448	0.551	0.000
T36.4 Tetracyclines	0.448	0.552	0.000
T42.4 Benzodiazepines	0.442	0.558	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.436	0.563	0.000
T36.8 Other systemic antibiotics	0.434	0.566	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.429	0.571	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.429	0.571	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.429	0.571	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.429	0.571	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.429	0.571	0.000
T44.0 Anticholinesterase agents	0.429	0.571	0.000
T38.9 Other and unspecified hormone antagonists	0.428	0.572	0.000
T38.7 Androgens and anabolic congeners	0.428	0.572	0.000
T38.5 Other oestrogens and progestogens	0.428	0.572	0.000
T38.4 Oral contraceptives	0.428	0.572	0.000
T38.2 Antithyroid drugs	0.428	0.572	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.426	0.574	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.425	0.575	0.000
T36.3 Macrolides	0.424	0.576	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.416	0.583	0.000
T46.7 Peripheral vasodilators	0.416	0.583	0.000
T40.5 Cocaine	0.416	0.584	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.414	0.586	0.000
T36.9 Systemic antibiotic, unspecified	0.414	0.586	0.000
T36.7 Antifungal antibiotics, systemically used	0.414	0.586	0.000
T36.6 Rifamycins	0.414	0.586	0.000
T36.5 Aminoglycosides	0.414	0.586	0.000
T36.2 Chloramphenicol group	0.414	0.586	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.414	0.586	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.413	0.587	0.000
T40.3 Methadone	0.412	0.588	0.000
T46.1 Calcium-channel blockers	0.409	0.590	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.408	0.592	0.000
T40.8 Lysergide [LSD]	0.408	0.592	0.000
T40.7 Cannabis (derivatives)	0.408	0.592	0.000
T40.0 Opium	0.408	0.592	0.000
T42.3 Barbiturates	0.405	0.595	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.403	0.596	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.403	0.597	0.000
T42.2 Succinimides and oxazolidinediones	0.403	0.597	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.397	0.603	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.389	0.611	0.000
T40.6 Other and unspecified narcotics	0.385	0.615	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.384	0.615	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.376	0.624	0.000
T48.5 Anti-common-cold drugs	0.369	0.631	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.366	0.634	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.364	0.636	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.364	0.636	0.000
T40.1 Heroin	0.359	0.641	0.000
T43.9 Psychotropic drug, unspecified	0.355	0.645	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.353	0.647	0.000
T48.4 Expectorants	0.353	0.647	0.000
T48.3 Antitussives	0.353	0.647	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.353	0.647	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.353	0.647	0.000
T48.0 Oxytocic drugs	0.353	0.647	0.000
T43.6 Psychostimulants with abuse potential	0.348	0.652	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.341	0.658	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.337	0.662	0.000
T45.8 Other primarily systemic and haematological agents	0.337	0.662	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.337	0.662	0.000
T45.6 Fibrinolysis-affecting drugs	0.337	0.662	0.000
T45.4 Iron and its compounds	0.337	0.662	0.000
T45.3 Enzymes, not elsewhere classified	0.337	0.662	0.000
T45.0 Antiallergic and antiemetic drugs	0.335	0.665	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.330	0.669	0.000
T49.9 Topical agent, unspecified	0.329	0.670	0.000
T49.8 Other topical agents	0.329	0.670	0.000
T49.7 Dental drugs, topically applied	0.329	0.670	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.329	0.670	0.000
T49.5 Ophthalmological drugs and preparations	0.329	0.670	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.329	0.670	0.000
T49.3 Emollients, demulcents and protectants	0.329	0.670	0.000
T49.2 Local astringents and local detergents	0.329	0.670	0.000
T49.1 Antipruritics	0.329	0.670	0.000
T45.2 Vitamins, not elsewhere classified	0.324	0.676	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.324	0.676	0.000
T41.5 Therapeutic gases	0.322	0.678	0.000
T41.4 Anaesthetic, unspecified	0.322	0.678	0.000
T41.3 Local anaesthetics	0.322	0.678	0.000
T41.1 Intravenous anaesthetics	0.322	0.678	0.000
T41.0 Inhaled anaesthetics	0.322	0.678	0.000
T47.2 Stimulant laxatives	0.315	0.685	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.312	0.688	0.000
T41.2 Other and unspecified general anaesthetics	0.305	0.695	0.000
T47.6 Antidiarrhoeal drugs	0.305	0.695	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.305	0.695	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.297	0.703	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.297	0.703	0.000
T47.7 Emetics	0.297	0.703	0.000
T47.5 Digestants	0.297	0.703	0.000
T47.3 Saline and osmotic laxatives	0.297	0.703	0.000
T47.4 Other laxatives	0.292	0.708	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.289	0.710	0.000
T37.5 Antiviral drugs	0.289	0.710	0.000
T37.4 Anthelminthics	0.289	0.710	0.000
T37.3 Other antiprotozoal drugs	0.289	0.710	0.000
T37.1 Antimycobacterial drugs	0.289	0.710	0.000
T37.0 Sulphonamides	0.289	0.710	0.000
T45.5 Anticoagulants	0.283	0.717	0.000
T47.0 Histamine H(2)-receptor antagonists	0.273	0.727	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.272	0.728	0.000
T40.4 Other synthetic narcotics	0.270	0.729	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.267	0.732	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.256	0.744	0.000
T50.8 Diagnostic agents	0.248	0.751	0.000
T50.1 Loop [high-ceiling] diuretics	0.247	0.753	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.246	0.754	0.000
T50.7 Analeptics and opioid receptor antagonists	0.245	0.755	0.000
T50.5 Appetite depressants	0.245	0.755	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.245	0.755	0.000
T50.0 Mineralocorticoids and their antagonists	0.245	0.755	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.228	0.771	0.000
T50.4 Drugs affecting uric acid metabolism	0.207	0.793	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.194	0.806	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.144	0.855	0.000
K29.8 Duodenitis	0.038	0.962	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.985	0.015
H50.1 Divergent concomitant strabismus	0.013	0.987	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.013	0.987	0.000
Z71.2 Person consulting for explanation of investigation findings	0.012	0.988	0.000
Z71.9 Counselling, unspecified	0.011	0.989	0.000
Z71.8 Other specified counselling	0.011	0.989	0.000
Z71.3 Dietary counselling and surveillance	0.011	0.989	0.000
Z71.1 Person with feared complaint in whom no diagnosis is made	0.011	0.989	0.000
K90.0 Coeliac disease	0.010	0.990	0.000
Z71.6 Tobacco abuse counselling	0.010	0.990	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.009	0.991	0.000
Z71.5 Drug abuse counselling and surveillance	0.009	0.991	0.000
Z71.0 Person consulting on behalf of another person	0.009	0.991	0.000
C83.3 Large cell (diffuse)	0.000	0.991	0.009
Z71.4 Alcohol abuse counselling and surveillance	0.009	0.991	0.000
H50 Other strabismus	0.008	0.992	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.992	0.008
H50.2 Vertical strabismus	0.008	0.992	0.000
Z73 Problems related to life-management difficulty	0.007	0.992	0.000
H50.5 Heterophoria	0.007	0.993	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.007	0.993	0.000
Z73.3 Stress, not elsewhere classified	0.007	0.993	0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.000	0.993	0.007
H50.4 Other and unspecified heterotropia	0.007	0.993	0.000
Z73.8 Other problems related to life-management difficulty	0.007	0.993	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.006	0.994	0.000
H50.8 Other specified strabismus	0.006	0.994	0.000
H50.0 Convergent concomitant strabismus	0.006	0.994	0.000
H50.3 Intermittent heterotropia	0.006	0.994	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.994	0.006
H50.6 Mechanical strabismus	0.006	0.994	0.000
Z73.5 Social role conflict, not elsewhere classified	0.006	0.994	0.000
Z73.4 Inadequate social skills, not elsewhere classified	0.006	0.994	0.000
Z73.2 Lack of relaxation and leisure	0.006	0.994	0.000
Z73.1 Accentuation of personality traits	0.006	0.994	0.000
Z73.0 Burn-out	0.006	0.994	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.994	0.006
Z75.3 Unavailability and inaccessibility of health-care facilities	0.005	0.994	0.000
Z73.6 Limitation of activities due to disability	0.005	0.995	0.000
Z75 Problems related to medical facilities and other health care	0.005	0.995	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.995	0.005
Z75.5 Holiday relief care	0.005	0.995	0.000
K90 Intestinal malabsorption	0.005	0.995	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.005	0.995	0.000
H50.9 Strabismus, unspecified	0.005	0.995	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.995	0.005
Z70 Counselling related to sexual attitude, behaviour and orientation	0.004	0.995	0.000
Z74 Problems related to care-provider dependency	0.004	0.995	0.000
Z75.8 Other problems related to medical facilities and other health care	0.004	0.996	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.996	0.004
F05.9 Delirium, unspecified	0.004	0.996	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.004	0.996	0.000
Z74.0 Reduced mobility	0.004	0.996	0.000
Z89 Acquired absence of limb	0.000	0.996	0.004
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.004	0.996	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.004	0.996	0.000
K90.8 Other intestinal malabsorption	0.004	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.004	0.996	0.000
Z75.0 Medical services not available in home	0.004	0.996	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.004	0.996	0.000
Z74.9 Problem related to care-provider dependency, unspecified	0.004	0.996	0.000
Z74.3 Need for continuous supervision	0.004	0.996	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.996	0.004
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.996	0.004
O69.3 Labour and delivery complicated by short cord	0.000	0.996	0.004
Z89.5 Acquired absence of leg at or below knee	0.000	0.996	0.004
Z75.4 Unavailability and inaccessibility of other helping agencies	0.004	0.996	0.000
K90.3 Pancreatic steatorrhoea	0.004	0.996	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.004	0.996	0.000
K90.1 Tropical sprue	0.004	0.996	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.996	0.004
Z70.9 Sex counselling, unspecified	0.003	0.996	0.000
Z70.8 Other sex counselling	0.003	0.996	0.000
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.003	0.996	0.000
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.003	0.996	0.000
Z70.0 Counselling related to sexual attitude	0.003	0.996	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.996	0.004
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.997	0.003
Z89.9 Acquired absence of limb, unspecified	0.000	0.997	0.003
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.003	0.997	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.997	0.003
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.003	0.997	0.000
Z91.5 Personal history of self-harm	0.003	0.997	0.000
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.003	0.997	0.000
Z76 Persons encountering health services in other circumstances	0.003	0.997	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.997	0.003
Z89.1 Acquired absence of hand and wrist	0.000	0.997	0.003
H61.2 Impacted cerumen	0.003	0.997	0.000
Z75.2 Other waiting period for investigation and treatment	0.003	0.997	0.000
Z41 Procedures for purposes other than remedying health state	0.000	0.997	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.997	0.003
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.003	0.997	0.000
K90.9 Intestinal malabsorption, unspecified	0.003	0.997	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.997	0.000
S61 Open wound of wrist and hand	0.000	0.997	0.003
S82.6 Fracture of lateral malleolus	0.000	0.997	0.003
I84.1 Internal haemorrhoids with other complications	0.003	0.997	0.000
Z99.3 Dependence on wheelchair	0.000	0.997	0.003
Z74.1 Need for assistance with personal care	0.002	0.997	0.000
H61.0 Perichondritis of external ear	0.003	0.997	0.000
I45.1 Other and unspecified right bundle-branch block	0.003	0.997	0.000
S61.7 Multiple open wounds of wrist and hand	0.000	0.997	0.003
H52.3 Anisometropia and aniseikonia	0.000	0.997	0.003
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
L29.0 Pruritus ani	0.003	0.997	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.000	0.997	0.003
Z41.2 Routine and ritual circumcision	0.000	0.997	0.002
Z74.8 Other problems related to care-provider dependency	0.002	0.997	0.000
Z76.5 Malingerer [conscious situation]	0.002	0.997	0.000
Z76.4 Other boarder in health-care facility	0.002	0.997	0.000
Z76.2 Health supervision and care of other healthy infant and child	0.002	0.997	0.000
Z76.1 Health supervision and care of foundling	0.002	0.997	0.000
Z76.0 Issue of repeat prescription	0.002	0.997	0.000
Z41.3 Ear piercing	0.000	0.997	0.002
Z41.0 Hair transplant	0.000	0.997	0.002
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.000	0.997	0.002
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
C91.1 Chronic lymphocytic leukaemia	0.003	0.997	0.000
Z74.2 Need for assistance at home and no other household member able to render care	0.002	0.997	0.000
Z11.2 Special screening examination for other bacterial diseases	0.002	0.997	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.002	0.997	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.997	0.002
Z76.8 Persons encountering health services in other specified circumstances	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
Z11 Special screening examination for infectious and parasitic diseases	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
M25.57 Pain in joint (Ankle and foot)	0.002	0.998	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.998	0.002
E10.1 With ketoacidosis	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
Z76.3 Healthy person accompanying sick person	0.002	0.998	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.002	0.998	0.000
Z11.5 Special screening examination for other viral diseases	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
C83.7 Burkitt's tumour	0.000	0.998	0.002
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
M79.08 Rheumatism, unspecified (Other)	0.002	0.998	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
Q60.0 Renal agenesis, unilateral	0.000	0.998	0.002
Z11.1 Special screening examination for respiratory tuberculosis	0.002	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
Z11.8 Special screening examination for other infectious and parasitic diseases	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
O40 Polyhydramnios	0.000	0.998	0.002
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.002	0.998	0.000
J39.2 Other diseases of pharynx	0.002	0.998	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.998	0.002
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.000	0.998	0.002
M79.0 Rheumatism, unspecified	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
L53.9 Erythematous condition, unspecified	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
D18.0 Haemangioma, any site	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
Q61 Cystic kidney disease	0.000	0.998	0.002
K62.6 Ulcer of anus and rectum	0.002	0.998	0.000
M84.2 Delayed union of fracture	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
W06.0 Home	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
M84.3 Stress fracture, not elsewhere classified	0.002	0.998	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.002
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.998	0.002
L29.2 Pruritus vulvae	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
Z76.9 Persons encountering health services in unspecified circumstances	0.001	0.998	0.000
R52.1 Chronic intractable pain	0.002	0.998	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.998	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.998	0.002
M84.27 Delayed union of fracture (Ankle and foot)	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M79.04 Rheumatism, unspecified (Hand)	0.002	0.998	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.002	0.998	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.002	0.998	0.000
M71.12 Other infective bursitis (Upper arm)	0.000	0.998	0.002
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.998	0.000
K59.8 Other specified functional intestinal disorders	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
L29 Pruritus	0.002	0.998	0.000
Q64 Other congenital malformations of urinary system	0.000	0.998	0.002
Z72 Problems related to lifestyle	0.002	0.998	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
Z49.0 Preparatory care for dialysis	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.001	0.998	0.000
M84.28 Delayed union of fracture (Other)	0.001	0.998	0.000
M84.24 Delayed union of fracture (Hand)	0.001	0.998	0.000
M84.23 Delayed union of fracture (Forearm)	0.001	0.998	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.001	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.998	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.998	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.998	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.998	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.998	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.998	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.998	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.998	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.998	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.001	0.998	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.001	0.998	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.001	0.998	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.001	0.998	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.001	0.998	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.001	0.998	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.001	0.998	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.001	0.998	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.001	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.998	0.002
M79.06 Rheumatism, unspecified (Lower leg)	0.001	0.998	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.001	0.998	0.000
L81.4 Other melanin hyperpigmentation	0.002	0.998	0.000
R50.8 Other specified fever	0.000	0.998	0.002
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.001	0.998	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.001	0.998	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.001	0.998	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.001	0.998	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.998	0.002
M84.83 Other disorders of continuity of bone (Forearm)	0.001	0.998	0.000
Q60.3 Renal hypoplasia, unilateral	0.000	0.998	0.001
Q60.2 Renal agenesis, unspecified	0.000	0.998	0.001
M84.22 Delayed union of fracture (Upper arm)	0.001	0.998	0.000
F05.1 Delirium superimposed on dementia	0.001	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.001	0.998	0.000
Q60.6 Potter's syndrome	0.000	0.998	0.001
Q60.5 Renal hypoplasia, unspecified	0.000	0.998	0.001
Q60.4 Renal hypoplasia, bilateral	0.000	0.998	0.001
Q60.1 Renal agenesis, bilateral	0.000	0.998	0.001
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.001
M84.26 Delayed union of fracture (Lower leg)	0.001	0.998	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.001	0.998	0.000
C83.0 Small cell (diffuse)	0.000	0.998	0.001
K92.9 Disease of digestive system, unspecified	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.001
Z72.5 High-risk sexual behaviour	0.001	0.998	0.000
Z72.6 Gambling and betting	0.001	0.998	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
K38.1 Appendicular concretions	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.001
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.002
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.001
F02.3 Dementia in Parkinson's disease	0.001	0.998	0.000
Q60-Q64 Congenital malformations of the urinary system	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.001	0.998	0.000
L29.1 Pruritus scroti	0.001	0.998	0.000
N75.0 Cyst of Bartholin's gland	0.001	0.998	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.998	0.001
Q64.8 Other specified congenital malformations of urinary system	0.000	0.998	0.001
Q64.6 Congenital diverticulum of bladder	0.000	0.998	0.001
Q64.5 Congenital absence of bladder and urethra	0.000	0.998	0.001
Q64.2 Congenital posterior urethral valves	0.000	0.998	0.001
Q64.1 Exstrophy of urinary bladder	0.000	0.998	0.001
Q64.0 Epispadias	0.000	0.998	0.001
Z72.9 Problem related to lifestyle, unspecified	0.001	0.999	0.000
Z72.3 Lack of physical exercise	0.001	0.999	0.000
D14.3 Bronchus and lung	0.001	0.999	0.000
L29.8 Other pruritus	0.001	0.999	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.001	0.999	0.000
H35.6 Retinal haemorrhage	0.001	0.999	0.000
Q64.4 Malformation of urachus	0.000	0.999	0.001
S27.0 Traumatic pneumothorax	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.999	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.999	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.001	0.999	0.000
C71.9 Brain, unspecified	0.000	0.999	0.001
D13.1 Stomach	0.000	0.999	0.001
K38.2 Diverticulum of appendix	0.000	0.999	0.001
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.999	0.001
X63.0 Home	0.001	0.999	0.000
H61.8 Other specified disorders of external ear	0.001	0.999	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.999	0.001
L81.8 Other specified disorders of pigmentation	0.001	0.999	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.001	0.999	0.000
C50.4 Upper-outer quadrant of breast	0.000	0.999	0.001
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.999	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.999	0.001
F02 Dementia in other diseases classified elsewhere	0.001	0.999	0.000
M71.16 Other infective bursitis (Lower leg)	0.000	0.999	0.001
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.999	0.001
K38.9 Disease of appendix, unspecified	0.000	0.999	0.001
N75.1 Abscess of Bartholin's gland	0.001	0.999	0.000
Z94.1 Heart transplant status	0.000	0.999	0.001
K38 Other diseases of appendix	0.000	0.999	0.001
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
L29.3 Anogenital pruritus, unspecified	0.001	0.999	0.000
L81.2 Freckles	0.001	0.999	0.000
Q63.2 Ectopic kidney	0.000	0.999	0.001
R22.1 Localised swelling, mass and lump, neck	0.001	0.999	0.000
Z94.0 Kidney transplant status	0.000	0.999	0.001
Q63 Other congenital malformations of kidney	0.000	0.999	0.001
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
D16.1 Short bones of upper limb	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.999	0.001
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.999	0.001
S50.1 Contusion of other and unspecified parts of forearm	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations