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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3864294
log Bayes Factor = 48.2882
Chromosome 6   position 28,641,957  (GRCh37) Explore rs3864294 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10.9 Without complications
0.000 0.141 0.859
E10 Insulin-dependent diabetes mellitus
0.000 0.147 0.853
E10.3 With ophthalmic complications
0.000 0.208 0.792
E10.6 With other specified complications
0.000 0.262 0.738
E10.4 With neurological complications
0.000 0.274 0.726
E10.1 With ketoacidosis
0.000 0.280 0.720
E10.2 With renal complications
0.000 0.282 0.718
E10.5 With peripheral circulatory complications
0.000 0.336 0.664
E10-E14 Diabetes mellitus
0.000 0.362 0.638
E10.0 With coma
0.000 0.377 0.622
E10.7 With multiple complications
0.000 0.388 0.612
E14 Unspecified diabetes mellitus
0.000 0.404 0.596
E13 Other specified diabetes mellitus
0.000 0.436 0.564
E14.9 Without complications
0.000 0.464 0.536
E13.9 Without complications
0.000 0.493 0.507
E10.8 With unspecified complications
0.000 0.499 0.500
E14.6 With other specified complications
0.000 0.531 0.469
E14.1 With ketoacidosis
0.000 0.540 0.460
E12 Malnutrition-related diabetes mellitus
0.000 0.543 0.457
E14.2 Withrenal complications
0.000 0.546 0.454
E14.5 With peripheral circulatory complications
0.000 0.560 0.440
E14.3 With ophthalmic complications
0.000 0.571 0.429
E14.7 With multiple complications
0.000 0.573 0.427
E14.0 With coma
0.000 0.573 0.427
K90 Intestinal malabsorption
0.000 0.577 0.423
E14.8 With unspecified complications
0.000 0.579 0.421
E14.4 With neurological complications
0.000 0.584 0.416
E13.3 With ophthalmic complications
0.000 0.585 0.415
E13.8 With unspecified complications
0.000 0.596 0.404
E13.7 With multiple complications
0.000 0.596 0.404
E13.6 With other specified complications
0.000 0.596 0.404
E13.5 With peripheral circulatory complications
0.000 0.596 0.404
E13.4 With neurological complications
0.000 0.596 0.404
E13.2 With renal complications
0.000 0.596 0.404
E13.1 With ketoacidosis
0.000 0.596 0.404
E13.0 With coma
0.000 0.596 0.404
E83 Disorders of mineral metabolism
0.403 0.597 0.000
E83.3 Disorders of phosphorus metabolism
0.380 0.620 0.000
K90.8 Other intestinal malabsorption
0.000 0.661 0.339
E12.9 Without complications
0.000 0.672 0.328
E12.8 With unspecified complications
0.000 0.672 0.328
E12.7 With multiple complications
0.000 0.672 0.328
E12.6 With other specified complications
0.000 0.672 0.328
E12.5 With peripheral circulatory complications
0.000 0.672 0.328
E12.4 With neurological complications
0.000 0.672 0.328
E12.3 With ophthalmic complications
0.000 0.672 0.328
E12.2 With renal complications
0.000 0.672 0.328
E12.1 With ketoacidosis
0.000 0.672 0.328
E12.0 With coma
0.000 0.672 0.328
K90.3 Pancreatic steatorrhoea
0.000 0.696 0.304
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.696 0.304
K90.1 Tropical sprue
0.000 0.696 0.304
K90.9 Intestinal malabsorption, unspecified
0.000 0.701 0.299
E83.8 Other disorders of mineral metabolism
0.289 0.711 0.000
E83.2 Disorders of zinc metabolism
0.289 0.711 0.000
E83.0 Disorders of copper metabolism
0.289 0.711 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.288 0.712 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.746 0.254
E83.4 Disorders of magnesium metabolism
0.224 0.776 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.850 0.150
E16 Other disorders of pancreatic internal secretion
0.000 0.859 0.141
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.862 0.138
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.864 0.136
E40-E46 Malnutrition
0.000 0.882 0.118
E46 Unspecified protein-energy malnutrition
0.000 0.895 0.105
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.898 0.101
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.898 0.101
E16.4 Abnormal secretion of gastrin
0.000 0.898 0.101
E16.3 Increased secretion of glucagon
0.000 0.898 0.101
E15 Nondiabetic hypoglycaemic coma
0.000 0.901 0.099
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.901 0.099
E16.1 Other hypoglycaemia
0.000 0.910 0.090
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.915 0.085
E45 Retarded development following protein-energy malnutrition
0.000 0.915 0.085
E43 Unspecified severe protein-energy malnutrition
0.000 0.915 0.085
E42 Marasmic kwashiorkor
0.000 0.915 0.085
E41 Nutritional marasmus
0.000 0.915 0.085
E40 Kwashiorkor
0.000 0.915 0.085
E65-E68 Obesity and other hyperalimentation
0.000 0.935 0.065
E44.1 Mild protein-energy malnutrition
0.000 0.939 0.061
E44.0 Moderate protein-energy malnutrition
0.000 0.939 0.061
E11 Non-insulin-dependent diabetes mellitus
0.000 0.939 0.061
E11.6 With other specified complications
0.000 0.942 0.058
E50-E64 Other nutritional deficiencies
0.000 0.945 0.055
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.054 0.946 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.053 0.947 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.049 0.951 0.000
E65 Localised adiposity
0.000 0.951 0.049
E67 Other hyperalimentation
0.000 0.953 0.047
E68 Sequelae of hyperalimentation
0.000 0.953 0.047
E11.7 With multiple complications
0.000 0.956 0.044
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.043 0.957 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.042 0.957 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.042 0.958 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.042 0.958 0.000
E83.5 Disorders of calcium metabolism
0.041 0.959 0.000
E51 Thiamine deficiency
0.000 0.959 0.041
E11.2 With renal complications
0.000 0.959 0.041
E56 Other vitamin deficiencies
0.000 0.959 0.041
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.961 0.039
E63 Other nutritional deficiencies
0.000 0.961 0.039
E50 Vitamin A deficiency
0.000 0.961 0.039
E60 Dietary zinc deficiency
0.000 0.961 0.039
E59 Dietary selenium deficiency
0.000 0.961 0.039
E54 Ascorbic acid deficiency
0.000 0.961 0.039
E52 Niacin deficiency [pellagra]
0.000 0.961 0.039
E53 Deficiency of other B group vitamins
0.000 0.961 0.039
E11.1 With ketoacidosis
0.000 0.961 0.039
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.039 0.961 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.038 0.962 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.038 0.962 0.000
E11.0 With coma
0.000 0.963 0.037
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.037 0.963 0.000
E11.8 With unspecified complications
0.000 0.964 0.036
E00-E07 Disorders of thyroid gland
0.000 0.964 0.036
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.965 0.035
E53.9 Vitamin B deficiency, unspecified
0.000 0.965 0.035
E67.8 Other specified hyperalimentation
0.000 0.966 0.033
E67.3 Hypervitaminosis D
0.000 0.966 0.033
E67.2 Megavitamin-B6 syndrome
0.000 0.966 0.033
E67.1 Hypercarotenaemia
0.000 0.966 0.033
E67.0 Hypervitaminosis A
0.000 0.966 0.033
E05.9 Thyrotoxicosis, unspecified
0.000 0.966 0.034
M05 Seropositive rheumatoid arthritis
0.033 0.967 0.000
M07.3 Other psoriatic arthropathies
0.000 0.967 0.032
E58 Dietary calcium deficiency
0.000 0.968 0.032
E11.5 With peripheral circulatory complications
0.000 0.968 0.032
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.968 0.031
E51.2 Wernicke's encephalopathy
0.000 0.969 0.031
K51.9 Ulcerative colitis, unspecified
0.031 0.969 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.969 0.031
E56.1 Deficiency of vitamin K
0.000 0.969 0.031
E51.9 Thiamine deficiency, unspecified
0.000 0.970 0.029
E51.8 Other manifestations of thiamine deficiency
0.000 0.970 0.029
E51.1 Beriberi
0.000 0.970 0.029
E56.9 Vitamin deficiency, unspecified
0.000 0.970 0.029
E56.8 Deficiency of other vitamins
0.000 0.970 0.029
E56.0 Deficiency of vitamin E
0.000 0.970 0.029
E50.9 Vitamin A deficiency, unspecified
0.000 0.971 0.028
E50.8 Other manifestations of vitamin A deficiency
0.000 0.971 0.028
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.971 0.028
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.971 0.028
E50.5 Vitamin A deficiency with night blindness
0.000 0.971 0.028
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.971 0.028
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.971 0.028
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.971 0.028
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.971 0.028
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.971 0.028
E63.9 Nutritional deficiency, unspecified
0.000 0.971 0.028
E63.8 Other specified nutritional deficiencies
0.000 0.971 0.028
E63.1 Imbalance of constituents of food intake
0.000 0.971 0.028
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.971 0.028
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.971 0.028
E64.8 Sequelae of other nutritional deficiencies
0.000 0.971 0.028
E64.3 Sequelae of rickets
0.000 0.971 0.028
E64.2 Sequelae of vitamin C deficiency
0.000 0.971 0.028
E64.1 Sequelae of vitamin A deficiency
0.000 0.971 0.028
E64.0 Sequelae of protein-energy malnutrition
0.000 0.971 0.028
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.972 0.028
E53.1 Pyridoxine deficiency
0.000 0.972 0.028
E53.0 Riboflavin deficiency
0.000 0.972 0.028
E61 Deficiency of other nutrient elements
0.000 0.972 0.028
M05.2 Rheumatoid vasculitis
0.027 0.973 0.000
E55 Vitamin D deficiency
0.000 0.974 0.026
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.974 0.026
E00 Congenital iodine-deficiency syndrome
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.974 0.025
M05.8 Other seropositive rheumatoid arthritis
0.025 0.975 0.000
E07 Other disorders of thyroid
0.000 0.975 0.025
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.975 0.025
M05.1 Rheumatoid lung disease
0.024 0.975 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.024 0.976 0.000
M05.0 Felty's syndrome
0.024 0.976 0.000
K51 Ulcerative colitis
0.024 0.976 0.000
M07.38 Other psoriatic arthropathies (Other)
0.000 0.976 0.023
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.976 0.023
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.976 0.023
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.976 0.023
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.976 0.023
E05.8 Other thyrotoxicosis
0.000 0.977 0.023
E05.5 Thyroid crisis or storm
0.000 0.977 0.023
E05.4 Thyrotoxicosis factitia
0.000 0.977 0.023
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.977 0.023
E06 Thyroiditis
0.000 0.978 0.022
M05.20 Rheumatoid vasculitis (Multiple sites)
0.022 0.978 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.978 0.021
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.978 0.021
M05.29 Rheumatoid vasculitis (Site unspecified)
0.021 0.979 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.979 0.021
E07.8 Other specified disorders of thyroid
0.000 0.979 0.021
K51.5 Mucosal proctocolitis
0.021 0.979 0.000
E61.9 Deficiency of nutrient element, unspecified
0.000 0.980 0.020
E61.8 Deficiency of other specified nutrient elements
0.000 0.980 0.020
E61.7 Deficiency of multiple nutrient elements
0.000 0.980 0.020
E61.6 Vanadium deficiency
0.000 0.980 0.020
E61.5 Molybdenum deficiency
0.000 0.980 0.020
E61.4 Chromium deficiency
0.000 0.980 0.020
E61.3 Manganese deficiency
0.000 0.980 0.020
E61.0 Copper deficiency
0.000 0.980 0.020
K51.3 Ulcerative (chronic) rectosigmoiditis
0.020 0.980 0.000
K51.4 Pseudopolyposis of colon
0.020 0.980 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.020 0.980 0.000
M05.28 Rheumatoid vasculitis (Other)
0.020 0.980 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.020 0.980 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.020 0.980 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.020 0.980 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.020 0.980 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.020 0.980 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.020 0.980 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.020 0.980 0.000
E55.0 Rickets, active
0.000 0.981 0.019
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.981 0.019
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.981 0.019
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.981 0.019
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.981 0.019
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.981 0.019
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.981 0.019
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.981 0.019
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.981 0.019
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.018
M05.19 Rheumatoid lung disease (Site unspecified)
0.018 0.981 0.000
E06.9 Thyroiditis, unspecified
0.000 0.982 0.018
K51.2 Ulcerative (chronic) proctitis
0.018 0.982 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.018 0.982 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.018 0.982 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.018 0.982 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.018 0.982 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.018 0.982 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.018 0.982 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.018 0.982 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.018 0.982 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.018 0.982 0.000
E07.1 Dyshormogenetic goitre
0.000 0.982 0.018
E07.0 Hypersecretion of calcitonin
0.000 0.982 0.018
M05.18 Rheumatoid lung disease (Other)
0.018 0.982 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.018 0.982 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.018 0.982 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.018 0.982 0.000
M05.14 Rheumatoid lung disease (Hand)
0.018 0.982 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.018 0.982 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.018 0.982 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.018 0.982 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.018 0.982 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.018 0.982 0.000
M05.09 Felty's syndrome (Site unspecified)
0.017 0.983 0.000
M05.08 Felty's syndrome (Other)
0.017 0.983 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.017 0.983 0.000
M05.06 Felty's syndrome (Lower leg)
0.017 0.983 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.017 0.983 0.000
M05.04 Felty's syndrome (Hand)
0.017 0.983 0.000
M05.03 Felty's syndrome (Forearm)
0.017 0.983 0.000
M05.02 Felty's syndrome (Upper arm)
0.017 0.983 0.000
M05.01 Felty's syndrome (Shoulder region)
0.017 0.983 0.000
M05.00 Felty's syndrome (Multiple sites)
0.017 0.983 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.017 0.983 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.017 0.983 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.017 0.983 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.017 0.983 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.017 0.983 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.017 0.983 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.017 0.983 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.017 0.983 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.017 0.983 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.017 0.983 0.000
E61.2 Magnesium deficiency
0.000 0.983 0.017
K51.0 Ulcerative (chronic) enterocolitis
0.017 0.983 0.000
E06.1 Subacute thyroiditis
0.000 0.983 0.017
E06.4 Drug-induced thyroiditis
0.000 0.984 0.016
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.984 0.016
E06.0 Acute thyroiditis
0.000 0.984 0.016
E06.5 Other chronic thyroiditis
0.000 0.984 0.015
E20-E35 Disorders of other endocrine glands
0.000 0.984 0.016
M07 Psoriatic and enteropathic arthropathies
0.002 0.985 0.014
E11.3 With ophthalmic complications
0.000 0.985 0.015
E61.1 Iron deficiency
0.000 0.985 0.014
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.986 0.014
L43.9 Lichen planus, unspecified
0.000 0.986 0.014
J31.0 Chronic rhinitis
0.000 0.986 0.014
E20 Hypoparathyroidism
0.000 0.986 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.013
E03 Other hypothyroidism
0.000 0.987 0.013
E20.9 Hypoparathyroidism, unspecified
0.000 0.987 0.013
E53.8 Deficiency of other specified B group vitamins
0.000 0.987 0.013
E24 Cushing's syndrome
0.000 0.987 0.013
E07.9 Disorder of thyroid, unspecified
0.000 0.988 0.012
E29 Testicular dysfunction
0.000 0.988 0.012
K51.8 Other ulcerative colitis
0.012 0.988 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.989 0.011
E32 Diseases of thymus
0.000 0.989 0.011
E30 Disorders of puberty, not elsewhere classified
0.000 0.989 0.011
E25 Adrenogenital disorders
0.000 0.989 0.011
L43 Lichen planus
0.000 0.989 0.011
M07.5 Arthropathy in ulcerative colitis
0.001 0.989 0.010
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.989 0.010
M07.2 Psoriatic spondylitis
0.001 0.989 0.010
M07.1 Arthritis mutilans
0.001 0.989 0.010
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.989 0.010
E31 Polyglandular dysfunction
0.000 0.989 0.011
E03.8 Other specified hypothyroidism
0.000 0.989 0.011
E11.4 With neurological complications
0.000 0.989 0.011
M07.6 Other enteropathic arthropathies
0.001 0.989 0.010
Z87.8 Personal history of other specified conditions
0.011 0.989 0.000
E20.8 Other hypoparathyroidism
0.000 0.990 0.010
E20.1 Pseudohypoparathyroidism
0.000 0.990 0.010
E20.0 Idiopathic hypoparathyroidism
0.000 0.990 0.010
L40.5 Arthropathic psoriasis
0.000 0.990 0.010
E24.9 Cushing's syndrome, unspecified
0.000 0.990 0.010
K92.2 Gastro-intestinal haemorrhage, unspecified
0.010 0.990 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.990 0.010
E24.0 Pituitary-dependent Cushing's disease
0.000 0.990 0.010
E03.5 Myxoedema coma
0.000 0.990 0.010
E03.4 Atrophy of thyroid (acquired)
0.000 0.990 0.010
E03.3 Postinfectious hypothyroidism
0.000 0.990 0.010
E21.3 Hyperparathyroidism, unspecified
0.000 0.990 0.010
E24.2 Drug-induced Cushing's syndrome
0.000 0.991 0.009
L40-L45 Papulosquamous disorders
0.000 0.991 0.009
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.991 0.009
E24.3 Ectopic ACTH syndrome
0.000 0.991 0.009
E24.1 Nelson's syndrome
0.000 0.991 0.009
E29.1 Testicular hypofunction
0.000 0.991 0.009
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.991 0.009
L40 Psoriasis
0.000 0.991 0.009
E28 Ovarian dysfunction
0.000 0.991 0.009
E29.9 Testicular dysfunction, unspecified
0.000 0.991 0.009
E29.8 Other testicular dysfunction
0.000 0.991 0.009
E29.0 Testicular hyperfunction
0.000 0.991 0.009
E24.8 Other Cushing's syndrome
0.000 0.991 0.009
E30.9 Disorder of puberty, unspecified
0.000 0.991 0.008
E30.8 Other disorders of puberty
0.000 0.991 0.008
E30.1 Precocious puberty
0.000 0.991 0.008
E30.0 Delayed puberty
0.000 0.991 0.008
E32.9 Disease of thymus, unspecified
0.000 0.991 0.008
E32.8 Other diseases of thymus
0.000 0.991 0.008
E32.1 Abscess of thymus
0.000 0.991 0.008
E32.0 Persistent hyperplasia of thymus
0.000 0.991 0.008
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.991 0.008
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.991 0.008
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.991 0.008
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.992 0.008
E25.9 Adrenogenital disorder, unspecified
0.000 0.992 0.008
E25.8 Other adrenogenital disorders
0.000 0.992 0.008
L43.3 Subacute (active) lichen planus
0.000 0.992 0.008
L43.2 Lichenoid drug reaction
0.000 0.992 0.008
L43.1 Bullous lichen planus
0.000 0.992 0.008
L43.0 Hypertrophic lichen planus
0.000 0.992 0.008
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.992 0.007
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.992 0.007
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.992 0.007
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.992 0.007
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.992 0.007
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.992 0.007
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.992 0.007
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.992 0.007
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.992 0.007
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.992 0.007
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.992 0.007
M07.18 Arthritis mutilans (Other)
0.001 0.992 0.007
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.992 0.007
M07.16 Arthritis mutilans (Lower leg)
0.001 0.992 0.007
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.992 0.007
M07.14 Arthritis mutilans (Hand)
0.001 0.992 0.007
M07.13 Arthritis mutilans (Forearm)
0.001 0.992 0.007
M07.12 Arthritis mutilans (Upper arm)
0.001 0.992 0.007
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.992 0.007
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.992 0.007
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.992 0.007
M07.28 Psoriatic spondylitis (Other)
0.001 0.992 0.007
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.992 0.007
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.992 0.007
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.992 0.007
M07.24 Psoriatic spondylitis (Hand)
0.001 0.992 0.007
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.992 0.007
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.992 0.007
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.992 0.007
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.992 0.007
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.992 0.007
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.992 0.007
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.992 0.007
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.992 0.007
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.992 0.007
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.992 0.007
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.992 0.007
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.992 0.007
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.992 0.007
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.992 0.007
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.992 0.007
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.992 0.007
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.992 0.007
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.992 0.007
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.992 0.007
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.992 0.007
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.992 0.007
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.992 0.007
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.992 0.007
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.992 0.007
E31.9 Polyglandular dysfunction, unspecified
0.000 0.992 0.008
E31.8 Other polyglandular dysfunction
0.000 0.992 0.008
E31.1 Polyglandular hyperfunction
0.000 0.992 0.008
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.001 0.992 0.007
E03.1 Congenital hypothyroidism without goitre
0.000 0.992 0.008
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.992 0.008
M07.68 Other enteropathic arthropathies (Other)
0.001 0.992 0.007
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.992 0.007
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.992 0.007
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.992 0.007
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.992 0.007
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.992 0.007
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.992 0.007
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.992 0.007
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.992 0.007
L42 Pityriasis rosea
0.000 0.992 0.008
E31.0 Autoimmune polyglandular failure
0.000 0.992 0.008
L43.8 Other lichen planus
0.000 0.992 0.008
E34 Other endocrine disorders
0.000 0.992 0.008
E26 Hyperaldosteronism
0.000 0.992 0.008
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.992 0.007
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.992 0.008
E21.4 Other specified disorders of parathyroid gland
0.000 0.993 0.007
E21.2 Other hyperparathyroidism
0.000 0.993 0.007
N50.8 Other specified disorders of male genital organs
0.000 0.993 0.007
E23 Hypofunction and other disorders of pituitary gland
0.000 0.993 0.007
D63.0 Anaemia in neoplastic disease
0.007 0.993 0.000
L44 Other papulosquamous disorders
0.000 0.993 0.007
L41 Parapsoriasis
0.000 0.993 0.007
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.993 0.007
L40.4 Guttate psoriasis
0.000 0.993 0.007
L40.2 Acrodermatitis continua
0.000 0.993 0.007
L40.1 Generalised pustular psoriasis
0.000 0.993 0.007
E28.9 Ovarian dysfunction, unspecified
0.000 0.993 0.007
E28.8 Other ovarian dysfunction
0.000 0.993 0.007
E28.1 Androgen excess
0.000 0.993 0.007
E28.0 Oestrogen excess
0.000 0.993 0.007
E66 Obesity
0.000 0.993 0.007
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.993 0.007
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.007 0.993 0.000
L40.3 Pustulosis palmaris et plantaris
0.000 0.993 0.006
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.993 0.006
E28.3 Primary ovarian failure
0.000 0.994 0.006
L40.8 Other psoriasis
0.000 0.994 0.006
L40.0 Psoriasis vulgaris
0.000 0.994 0.006
E34.9 Endocrine disorder, unspecified
0.000 0.994 0.006
L40.9 Psoriasis, unspecified
0.000 0.994 0.006
E22 Hyperfunction of pituitary gland
0.000 0.994 0.006
E34.5 Androgen resistance syndrome
0.000 0.994 0.006
E34.4 Constitutional tall stature
0.000 0.994 0.006
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.994 0.006
E34.1 Other hypersecretion of intestinal hormones
0.000 0.994 0.006
E26.8 Other hyperaldosteronism
0.000 0.994 0.006
E26.1 Secondary hyperaldosteronism
0.000 0.994 0.006
E55.9 Vitamin D deficiency, unspecified
0.000 0.994 0.006
E23.2 Diabetes insipidus
0.000 0.994 0.006
J38.4 Oedema of larynx
0.006 0.994 0.000
E34.8 Other specified endocrine disorders
0.000 0.994 0.005
E06.3 Autoimmune thyroiditis
0.000 0.995 0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.995 0.005
E23.1 Drug-induced hypopituitarism
0.000 0.995 0.005
E34.3 Short stature, not elsewhere classified
0.000 0.995 0.005
E26.9 Hyperaldosteronism, unspecified
0.000 0.995 0.005
E27 Other disorders of adrenal gland
0.000 0.995 0.005
L41.9 Parapsoriasis, unspecified
0.000 0.995 0.005
L41.8 Other parapsoriasis
0.000 0.995 0.005
L41.5 Retiform parapsoriasis
0.000 0.995 0.005
L41.4 Large plaque parapsoriasis
0.000 0.995 0.005
L41.3 Small plaque parapsoriasis
0.000 0.995 0.005
L41.2 Lymphomatoid papulosis
0.000 0.995 0.005
L41.1 Pityriasis lichenoides chronica
0.000 0.995 0.005
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.995 0.005
L44.9 Papulosquamous disorder, unspecified
0.000 0.995 0.005
L44.8 Other specified papulosquamous disorders
0.000 0.995 0.005
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.995 0.005
L44.3 Lichen ruber moniliformis
0.000 0.995 0.005
L44.2 Lichen striatus
0.000 0.995 0.005
L44.1 Lichen nitidus
0.000 0.995 0.005
L44.0 Pityriasis rubra pilaris
0.000 0.995 0.005
E23.7 Disorder of pituitary gland, unspecified
0.000 0.995 0.005
E66.1 Drug-induced obesity
0.000 0.995 0.005
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.005 0.995 0.000
T63.4 Venom of other arthropods
0.005 0.995 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.995 0.005
T80.2 Infections following infusion, transfusion and therapeutic injection
0.000 0.995 0.005
E22.8 Other hyperfunction of pituitary gland
0.000 0.995 0.004
M05-M14 Inflammatory polyarthropathies
0.004 0.995 0.001
I71 Aortic aneurysm and dissection
0.005 0.995 0.000
E66.0 Obesity due to excess calories
0.000 0.995 0.004
R25.2 Cramp and spasm
0.000 0.995 0.004
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.996 0.004
M06.3 Rheumatoid nodule
0.004 0.996 0.000
H40.2 Primary angle-closure glaucoma
0.004 0.996 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.996 0.004
M06.34 Rheumatoid nodule (Hand)
0.004 0.996 0.000
E34.0 Carcinoid syndrome
0.000 0.996 0.004
M06 Other rheumatoid arthritis
0.004 0.996 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.004 0.996 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.996 0.004
E27.0 Other adrenocortical overactivity
0.000 0.996 0.004
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.996 0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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