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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3868075
log Bayes Factor = 59.8234
Chromosome 6   position 31,167,815  (GRCh37) Explore rs3868075 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
R31 Unspecified haematuria
0.997 0.003 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.005 0.995
D80-D89 Certain disorders involving the immune mechanism
0.000 0.006 0.994
D86 Sarcoidosis
0.000 0.007 0.993
D86.9 Sarcoidosis, unspecified
0.000 0.012 0.988
L40 Psoriasis
0.000 0.014 0.986
D60-D64 Aplastic and other anaemias
0.000 0.014 0.986
D64 Other anaemias
0.000 0.019 0.981
D64.9 Anaemia, unspecified
0.000 0.025 0.975
L40.5 Arthropathic psoriasis
0.000 0.032 0.968
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.032 0.968
D69 Purpura and other haemorrhagic conditions
0.000 0.040 0.960
D69.6 Thrombocytopenia, unspecified
0.000 0.045 0.955
D50-D53 Nutritional anaemias
0.000 0.076 0.924
D86.3 Sarcoidosis of skin
0.000 0.077 0.923
D80 Immunodeficiency with predominantly antibody defects
0.000 0.100 0.900
L40.0 Psoriasis vulgaris
0.000 0.120 0.880
E03 Other hypothyroidism
0.000 0.147 0.853
D66 Hereditary factor VIII deficiency
0.000 0.148 0.852
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.166 0.834
D62 Acute posthaemorrhagic anaemia
0.000 0.167 0.833
D69.2 Other nonthrombocytopenic purpura
0.000 0.177 0.823
D51 Vitamin B12 deficiency anaemia
0.000 0.187 0.813
D64.8 Other specified anaemias
0.000 0.192 0.808
D69.4 Other primary thrombocytopenia
0.000 0.196 0.804
L40.1 Generalised pustular psoriasis
0.000 0.197 0.803
D55-D59 Haemolytic anaemias
0.000 0.199 0.801
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.201 0.799
D50 Iron deficiency anaemia
0.000 0.211 0.789
D70 Agranulocytosis
0.000 0.211 0.789
D69.5 Secondary thrombocytopenia
0.000 0.216 0.784
D84 Other immunodeficiencies
0.000 0.228 0.772
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.228 0.772
D50.9 Iron deficiency anaemia, unspecified
0.000 0.228 0.772
D61 Other aplastic anaemias
0.000 0.231 0.769
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.233 0.767
D86.0 Sarcoidosis of lung
0.000 0.235 0.765
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.238 0.762
D52 Folate deficiency anaemia
0.000 0.241 0.759
L40.8 Other psoriasis
0.000 0.264 0.735
L40.3 Pustulosis palmaris et plantaris
0.000 0.266 0.734
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.270 0.730
D83 Common variable immunodeficiency
0.000 0.270 0.729
E00-E07 Disorders of thyroid gland
0.000 0.274 0.726
D72 Other disorders of white blood cells
0.000 0.281 0.719
L40.4 Guttate psoriasis
0.000 0.281 0.719
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.282 0.718
D81 Combined immunodeficiencies
0.000 0.287 0.713
L40.2 Acrodermatitis continua
0.000 0.293 0.707
E05.9 Thyrotoxicosis, unspecified
0.000 0.293 0.707
D64.4 Congenital dyserythropoietic anaemia
0.000 0.297 0.703
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.297 0.703
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.297 0.703
D64.0 Hereditary sideroblastic anaemia
0.000 0.297 0.703
D86.1 Sarcoidosis of lymph nodes
0.000 0.302 0.698
D64.3 Other sideroblastic anaemias
0.000 0.303 0.697
D69.8 Other specified haemorrhagic conditions
0.000 0.312 0.688
D59 Acquired haemolytic anaemia
0.000 0.330 0.670
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.332 0.668
D58 Other hereditary haemolytic anaemias
0.000 0.351 0.649
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.351 0.649
E03.8 Other specified hypothyroidism
0.000 0.354 0.646
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.355 0.645
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.355 0.645
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.355 0.645
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.355 0.645
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.355 0.645
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.356 0.644
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.356 0.644
D67 Hereditary factor IX deficiency
0.000 0.357 0.643
D52.9 Folate deficiency anaemia, unspecified
0.000 0.360 0.640
D69.1 Qualitative platelet defects
0.000 0.368 0.632
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.368 0.632
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.370 0.630
D61.9 Aplastic anaemia, unspecified
0.000 0.371 0.629
D84.9 Immunodeficiency, unspecified
0.000 0.373 0.627
D82 Immunodeficiency associated with other major defects
0.000 0.374 0.626
D84.1 Defects in the complement system
0.000 0.384 0.616
E03.5 Myxoedema coma
0.000 0.388 0.611
E03.4 Atrophy of thyroid (acquired)
0.000 0.388 0.611
E03.3 Postinfectious hypothyroidism
0.000 0.388 0.611
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.389 0.611
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.392 0.608
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.397 0.603
E03.1 Congenital hypothyroidism without goitre
0.000 0.399 0.601
D74 Methaemoglobinaemia
0.000 0.402 0.598
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.000 0.402 0.598
D71 Functional disorders of polymorphonuclear neutrophils
0.000 0.402 0.598
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.405 0.595
D72.1 Eosinophilia
0.000 0.409 0.591
D72.8 Other specified disorders of white blood cells
0.000 0.412 0.588
D51.2 Transcobalamin II deficiency
0.000 0.417 0.583
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.417 0.583
D58.0 Hereditary spherocytosis
0.000 0.417 0.582
D59.1 Other autoimmune haemolytic anaemias
0.000 0.425 0.575
D57 Sickle-cell disorders
0.000 0.426 0.574
D55 Anaemia due to enzyme disorders
0.000 0.426 0.574
D61.0 Constitutional aplastic anaemia
0.000 0.430 0.570
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.433 0.567
D50.1 Sideropenic dysphagia
0.000 0.434 0.566
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.436 0.564
D53 Other nutritional anaemias
0.000 0.436 0.564
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.439 0.561
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.445 0.555
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.446 0.553
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.446 0.553
D89.3 Immune reconstitution syndrome
0.000 0.446 0.553
D61.8 Other specified aplastic anaemias
0.000 0.449 0.551
D61.3 Idiopathic aplastic anaemia
0.000 0.449 0.551
D61.2 Aplastic anaemia due to other external agents
0.000 0.449 0.551
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.450 0.550
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.453 0.547
D86.8 Sarcoidosis of other and combined sites
0.000 0.454 0.546
D52.8 Other folate deficiency anaemias
0.000 0.456 0.544
D52.1 Drug-induced folate deficiency anaemia
0.000 0.456 0.544
D52.0 Dietary folate deficiency anaemia
0.000 0.456 0.544
D83.9 Common variable immunodeficiency, unspecified
0.000 0.460 0.540
D69.3 Idiopathic thrombocytopenic purpura
0.000 0.467 0.533
D83.8 Other common variable immunodeficiencies
0.000 0.477 0.523
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.477 0.523
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.477 0.523
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.477 0.523
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.479 0.521
E00 Congenital iodine-deficiency syndrome
0.000 0.479 0.521
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.482 0.518
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.482 0.518
D69.0 Allergic purpura
0.000 0.483 0.517
D72.9 Disorder of white blood cells, unspecified
0.000 0.484 0.515
D72.0 Genetic anomalies of leukocytes
0.000 0.484 0.515
E05.5 Thyroid crisis or storm
0.000 0.485 0.515
E05.4 Thyrotoxicosis factitia
0.000 0.485 0.515
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.485 0.515
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.485 0.515
D81.9 Combined immunodeficiency, unspecified
0.000 0.489 0.511
D81.8 Other combined immunodeficiencies
0.000 0.489 0.511
D81.7 Major histocompatibility complex class II deficiency
0.000 0.489 0.511
D81.6 Major histocompatibility complex class I deficiency
0.000 0.489 0.511
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.489 0.511
D81.4 Nezelof's syndrome
0.000 0.489 0.511
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.489 0.511
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.489 0.511
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.489 0.511
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.489 0.511
D76.3 Other histiocytosis syndromes
0.000 0.493 0.507
D61.1 Drug-induced aplastic anaemia
0.000 0.495 0.505
D59.8 Other acquired haemolytic anaemias
0.000 0.519 0.480
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.519 0.480
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.519 0.480
D59.3 Haemolytic-uraemic syndrome
0.000 0.519 0.480
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.519 0.480
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.519 0.480
D60.8 Other acquired pure red cell aplasias
0.000 0.521 0.479
D60.1 Transient acquired pure red cell aplasia
0.000 0.521 0.479
D60.0 Chronic acquired pure red cell aplasia
0.000 0.521 0.479
D69.9 Haemorrhagic condition, unspecified
0.000 0.530 0.470
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.535 0.465
D58.1 Hereditary elliptocytosis
0.000 0.535 0.465
D76.2 Haemophagocytic syndrome, infection-associated
0.000 0.538 0.462
D76.1 Haemophagocytic lymphohistiocytosis
0.000 0.538 0.462
D76.0 Langerhans' cell histiocytosis, not elsewhere classified
0.000 0.538 0.462
D89.1 Cryoglobulinaemia
0.000 0.539 0.461
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.551 0.449
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.551 0.449
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.551 0.449
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.551 0.449
D82.2 Immunodeficiency with short-limbed stature
0.000 0.551 0.449
D82.0 Wiskott-Aldrich syndrome
0.000 0.551 0.449
K90 Intestinal malabsorption
0.000 0.551 0.449
E07 Other disorders of thyroid
0.000 0.555 0.445
D56 Thalassaemia
0.000 0.558 0.442
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.560 0.440
D58.2 Other haemoglobinopathies
0.000 0.562 0.437
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.563 0.437
D84.8 Other specified immunodeficiencies
0.000 0.564 0.435
E04 Other non-toxic goitre
0.000 0.567 0.433
D74.9 Methaemoglobinaemia, unspecified
0.000 0.571 0.429
D74.8 Other methaemoglobinaemias
0.000 0.571 0.429
D74.0 Congenital methaemoglobinaemia
0.000 0.571 0.429
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.588 0.412
D55.8 Other anaemias due to enzyme disorders
0.000 0.588 0.412
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.588 0.412
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.588 0.412
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.588 0.412
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.588 0.412
D57.8 Other sickle-cell disorders
0.000 0.588 0.412
D57.3 Sickle-cell trait
0.000 0.588 0.412
D57.2 Double heterozygous sickling disorders
0.000 0.588 0.412
D57.1 Sickle-cell anaemia without crisis
0.000 0.588 0.412
D57.0 Sickle-cell anaemia with crisis
0.000 0.588 0.412
D53.8 Other specified nutritional anaemias
0.000 0.595 0.404
D53.2 Scorbutic anaemia
0.000 0.595 0.404
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.595 0.404
D53.0 Protein deficiency anaemia
0.000 0.595 0.404
K75 Other inflammatory liver diseases
0.000 0.601 0.399
K75.4 Autoimmune hepatitis
0.000 0.607 0.393
E04.0 Non-toxic diffuse goitre
0.000 0.607 0.393
K70-K77 Diseases of liver
0.000 0.609 0.391
K75.8 Other specified inflammatory liver diseases
0.000 0.610 0.390
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.614 0.386
K73 Chronic hepatitis, not elsewhere classified
0.000 0.615 0.385
E06 Thyroiditis
0.000 0.617 0.382
K70 Alcoholic liver disease
0.000 0.620 0.380
E07.8 Other specified disorders of thyroid
0.000 0.625 0.375
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.626 0.373
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.626 0.373
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.626 0.373
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.626 0.373
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.626 0.373
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.626 0.373
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.626 0.373
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.626 0.373
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.632 0.368
D82.1 Di George's syndrome
0.001 0.638 0.361
K73.9 Chronic hepatitis, unspecified
0.000 0.648 0.352
K90.9 Intestinal malabsorption, unspecified
0.000 0.652 0.348
D50.8 Other iron deficiency anaemias
0.000 0.653 0.347
K70.9 Alcoholic liver disease, unspecified
0.000 0.653 0.347
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.656 0.344
E05.8 Other thyrotoxicosis
0.001 0.657 0.343
K70.1 Alcoholic hepatitis
0.000 0.658 0.342
K70.0 Alcoholic fatty liver
0.000 0.665 0.335
K72 Hepatic failure, not elsewhere classified
0.000 0.672 0.328
K90.3 Pancreatic steatorrhoea
0.000 0.678 0.322
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.678 0.322
K90.1 Tropical sprue
0.000 0.678 0.322
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.680 0.320
E07.1 Dyshormogenetic goitre
0.000 0.681 0.319
E07.0 Hypersecretion of calcitonin
0.000 0.681 0.319
K75.0 Abscess of liver
0.000 0.681 0.319
D56.9 Thalassaemia, unspecified
0.000 0.683 0.317
D56.8 Other thalassaemias
0.000 0.683 0.317
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.683 0.317
D56.2 Delta-beta thalassaemia
0.000 0.683 0.317
D56.0 Alpha thalassaemia
0.000 0.683 0.317
E06.3 Autoimmune thyroiditis
0.000 0.685 0.315
E04.8 Other specified non-toxic goitre
0.000 0.690 0.310
D53.9 Nutritional anaemia, unspecified
0.000 0.694 0.305
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.695 0.305
K75.2 Nonspecific reactive hepatitis
0.000 0.714 0.286
K75.1 Phlebitis of portal vein
0.000 0.714 0.286
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.715 0.285
K72.0 Acute and subacute hepatic failure
0.000 0.716 0.284
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.716 0.283
K77 Liver disorders in diseases classified elsewhere
0.000 0.719 0.280
K74 Fibrosis and cirrhosis of liver
0.000 0.720 0.280
D56.1 Beta thalassaemia
0.001 0.722 0.278
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.723 0.276
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.723 0.276
K74.0 Hepatic fibrosis
0.000 0.725 0.275
E06.4 Drug-induced thyroiditis
0.000 0.725 0.274
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.725 0.274
E06.0 Acute thyroiditis
0.000 0.725 0.274
E04.2 Non-toxic multinodular goitre
0.000 0.726 0.274
E06.5 Other chronic thyroiditis
0.000 0.733 0.267
D75 Other diseases of blood and blood-forming organs
0.000 0.749 0.251
K72.9 Hepatic failure, unspecified
0.000 0.752 0.248
K90.8 Other intestinal malabsorption
0.000 0.752 0.247
D56.3 Thalassaemia trait
0.001 0.753 0.246
K71 Toxic liver disease
0.000 0.767 0.233
K70.4 Alcoholic hepatic failure
0.000 0.775 0.225
D73 Diseases of spleen
0.000 0.776 0.223
K72.1 Chronic hepatic failure
0.000 0.782 0.218
E04.1 Non-toxic single thyroid nodule
0.000 0.788 0.212
D75.0 Familial erythrocytosis
0.000 0.794 0.205
D75.9 Disease of blood and blood-forming organs, unspecified
0.000 0.796 0.204
D63.1 Anaemia in other chronic diseases classified elsewhere
0.000 0.796 0.203
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.799 0.201
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.799 0.201
K74.4 Secondary biliary cirrhosis
0.000 0.799 0.201
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.799 0.201
E06.9 Thyroiditis, unspecified
0.001 0.801 0.199
M06.9 Rheumatoid arthritis, unspecified
0.194 0.806 0.000
M06 Other rheumatoid arthritis
0.188 0.812 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.818 0.182
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.180 0.820 0.000
K74.1 Hepatic sclerosis
0.000 0.821 0.179
L40-L45 Papulosquamous disorders
0.001 0.822 0.178
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.175 0.825 0.000
D73.1 Hypersplenism
0.000 0.829 0.170
M06.0 Seronegative rheumatoid arthritis
0.170 0.830 0.000
M06.3 Rheumatoid nodule
0.169 0.831 0.000
K71.9 Toxic liver disease, unspecified
0.000 0.833 0.167
K71.8 Toxic liver disease with other disorders of liver
0.000 0.833 0.167
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.833 0.167
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.833 0.167
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.833 0.167
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.833 0.167
K71.2 Toxic liver disease with acute hepatitis
0.000 0.833 0.167
K71.0 Toxic liver disease with cholestasis
0.000 0.833 0.167
K70.3 Alcoholic cirrhosis of liver
0.000 0.834 0.166
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.166 0.834 0.000
E06.1 Subacute thyroiditis
0.001 0.835 0.164
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.163 0.837 0.000
M06.34 Rheumatoid nodule (Hand)
0.161 0.839 0.000
D73.2 Chronic congestive splenomegaly
0.000 0.839 0.160
D73.9 Disease of spleen, unspecified
0.000 0.840 0.160
D73.3 Abscess of spleen
0.000 0.841 0.159
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.158 0.842 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.158 0.842 0.000
D73.5 Infarction of spleen
0.000 0.843 0.157
E04.9 Non-toxic goitre, unspecified
0.000 0.846 0.154
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.154 0.846 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.153 0.847 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.149 0.851 0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.851 0.148
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.146 0.854 0.000
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.855 0.145
M06.8 Other specified rheumatoid arthritis
0.139 0.861 0.000
M06.4 Inflammatory polyarthropathy
0.138 0.862 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.138 0.862 0.000
M05 Seropositive rheumatoid arthritis
0.136 0.864 0.000
M05-M14 Inflammatory polyarthropathies
0.136 0.864 0.000
M06.2 Rheumatoid bursitis
0.135 0.865 0.000
M06.1 Adult-onset Still's disease
0.135 0.865 0.000
D73.4 Cyst of spleen
0.001 0.866 0.134
M06.04 Seronegative rheumatoid arthritis (Hand)
0.131 0.869 0.000
G35 Multiple sclerosis
0.000 0.869 0.131
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.130 0.870 0.000
K74.5 Biliary cirrhosis, unspecified
0.000 0.872 0.128
L44 Other papulosquamous disorders
0.001 0.872 0.127
L41 Parapsoriasis
0.001 0.872 0.127
L45 Papulosquamous disorders in diseases classified elsewhere
0.001 0.872 0.127
K74.6 Other and unspecified cirrhosis of liver
0.000 0.873 0.127
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.127 0.873 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.125 0.875 0.000
M06.33 Rheumatoid nodule (Forearm)
0.124 0.876 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.122 0.878 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.122 0.878 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.122 0.878 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.121 0.878 0.000
M06.38 Rheumatoid nodule (Other)
0.121 0.878 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.121 0.878 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.121 0.878 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.121 0.878 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.120 0.880 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.119 0.881 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.118 0.882 0.000
D75.2 Essential thrombocytosis
0.000 0.884 0.115
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.115 0.885 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.113 0.886 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.000 0.887 0.113
D73.8 Other diseases of spleen
0.001 0.889 0.110
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.111 0.889 0.000
M14 Arthropathies in other diseases classified elsewhere
0.110 0.890 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.110 0.890 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.110 0.890 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.109 0.891 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.107 0.892 0.000
M05.1 Rheumatoid lung disease
0.106 0.894 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.105 0.895 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.105 0.895 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.104 0.895 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.102 0.898 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.100 0.900 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.100 0.900 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.100 0.900 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.100 0.900 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.100 0.900 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.100 0.900 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.100 0.900 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.100 0.900 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.100 0.900 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.100 0.900 0.000
M08 Juvenile arthritis
0.099 0.900 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.099 0.901 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.099 0.901 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.099 0.901 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.099 0.901 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.099 0.901 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.099 0.901 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.099 0.901 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.099 0.901 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.099 0.901 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.098 0.902 0.000
M05.0 Felty's syndrome
0.098 0.902 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.097 0.902 0.000
M05.2 Rheumatoid vasculitis
0.097 0.903 0.000
L42 Pityriasis rosea
0.001 0.903 0.096
M06.19 Adult-onset Still's disease (Site unspecified)
0.097 0.903 0.000
M06.18 Adult-onset Still's disease (Other)
0.097 0.903 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.097 0.903 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.097 0.903 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.097 0.903 0.000
M06.14 Adult-onset Still's disease (Hand)
0.097 0.903 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.097 0.903 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.097 0.903 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.097 0.903 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.097 0.903 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.097 0.903 0.000
M06.28 Rheumatoid bursitis (Other)
0.097 0.903 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.097 0.903 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.097 0.903 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.097 0.903 0.000
M06.24 Rheumatoid bursitis (Hand)
0.097 0.903 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.097 0.903 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.097 0.903 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.097 0.903 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.097 0.903 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.096 0.904 0.000
K75.9 Inflammatory liver disease, unspecified
0.001 0.906 0.094
M11 Other crystal arthropathies
0.094 0.906 0.000
M14.6 Neuropathic arthropathy
0.093 0.907 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.093 0.907 0.000
L41.9 Parapsoriasis, unspecified
0.001 0.908 0.092
L41.8 Other parapsoriasis
0.001 0.908 0.092
L41.5 Retiform parapsoriasis
0.001 0.908 0.092
L41.4 Large plaque parapsoriasis
0.001 0.908 0.092
L41.3 Small plaque parapsoriasis
0.001 0.908 0.092
L41.2 Lymphomatoid papulosis
0.001 0.908 0.092
L41.1 Pityriasis lichenoides chronica
0.001 0.908 0.092
L41.0 Pityriasis lichenoides et varioliformis acuta
0.001 0.908 0.092
L44.9 Papulosquamous disorder, unspecified
0.001 0.908 0.092
L44.8 Other specified papulosquamous disorders
0.001 0.908 0.092
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.001 0.908 0.092
L44.3 Lichen ruber moniliformis
0.001 0.908 0.092
L44.2 Lichen striatus
0.001 0.908 0.092
L44.1 Lichen nitidus
0.001 0.908 0.092
L44.0 Pityriasis rubra pilaris
0.001 0.908 0.092
M12 Other specific arthropathies
0.091 0.909 0.000
M05.8 Other seropositive rheumatoid arthritis
0.089 0.911 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.089 0.911 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.084 0.916 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.917 0.083
D68 Other coagulation defects
0.000 0.918 0.082
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.079 0.921 0.000
M14.4 Arthropathy in amyloidosis
0.079 0.921 0.000
M14.3 Lipoid dermatoarthritis
0.079 0.921 0.000
M14.2 Diabetic arthropathy
0.079 0.921 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.079 0.921 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.079 0.921 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.076 0.923 0.000
M05.18 Rheumatoid lung disease (Other)
0.076 0.924 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.076 0.924 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.076 0.924 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.076 0.924 0.000
M05.14 Rheumatoid lung disease (Hand)
0.076 0.924 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.076 0.924 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.076 0.924 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.076 0.924 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.076 0.924 0.000
M11.9 Crystal arthropathy, unspecified
0.074 0.926 0.000
M08.0 Juvenile rheumatoid arthritis
0.073 0.926 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.926 0.074
M13 Other arthritis
0.073 0.927 0.000
M08.9 Juvenile arthritis, unspecified
0.071 0.928 0.000
M08.8 Other juvenile arthritis
0.071 0.928 0.000
M08.4 Pauciarticular juvenile arthritis
0.071 0.928 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.071 0.928 0.000
M08.2 Juvenile arthritis with systemic onset
0.071 0.928 0.000
M08.1 Juvenile ankylosing spondylitis
0.071 0.928 0.000
M07 Psoriatic and enteropathic arthropathies
0.062 0.929 0.009
M05.09 Felty's syndrome (Site unspecified)
0.070 0.930 0.000
M05.08 Felty's syndrome (Other)
0.070 0.930 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.070 0.930 0.000
M05.06 Felty's syndrome (Lower leg)
0.070 0.930 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.070 0.930 0.000
M05.04 Felty's syndrome (Hand)
0.070 0.930 0.000
M05.03 Felty's syndrome (Forearm)
0.070 0.930 0.000
M05.02 Felty's syndrome (Upper arm)
0.070 0.930 0.000
M05.01 Felty's syndrome (Shoulder region)
0.070 0.930 0.000
M05.00 Felty's syndrome (Multiple sites)
0.070 0.930 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.070 0.930 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.070 0.930 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.070 0.930 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.070 0.930 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.070 0.930 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.070 0.930 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.070 0.930 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.070 0.930 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.070 0.930 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.070 0.930 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.070 0.930 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.070 0.930 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.070 0.930 0.000
M09.0 Juvenile arthritis in psoriasis
0.070 0.930 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.070 0.930 0.000
M05.28 Rheumatoid vasculitis (Other)
0.070 0.930 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.070 0.930 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.070 0.930 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.070 0.930 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.070 0.930 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.070 0.930 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.070 0.930 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.070 0.930 0.000
M10 Gout
0.069 0.931 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.069 0.931 0.000
M11.8 Other specified crystal arthropathies
0.068 0.932 0.000
M11.1 Familial chondrocalcinosis
0.068 0.932 0.000
M11.0 Hydroxyapatite deposition disease
0.068 0.932 0.000
D68.6 Other Thrombophilia
0.000 0.934 0.066
K74.3 Primary biliary cirrhosis
0.000 0.934 0.066
K90-K93 Other diseases of the digestive system
0.000 0.934 0.066
M12.8 Other specific arthropathies, not elsewhere classified
0.065 0.935 0.000
M12.5 Traumatic arthropathy
0.065 0.935 0.000
M12.4 Intermittent hydrarthrosis
0.065 0.935 0.000
M12.1 Kaschin-Beck disease
0.065 0.935 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.065 0.935 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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