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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3871467
log Bayes Factor = 30.2882
Chromosome 6   position 29,677,249  (GRCh37) Explore rs3871467 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.001 0.999
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.046 0.954
G37 Other demyelinating diseases of central nervous system
0.000 0.056 0.944
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.072 0.928
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.146 0.854
G36 Other acute disseminated demyelination
0.000 0.305 0.695
G37.5 Concentric sclerosis [Balo]
0.000 0.323 0.677
G37.4 Subacute necrotising myelitis
0.000 0.323 0.677
G37.2 Central pontine myelinolysis
0.000 0.323 0.677
G37.1 Central demyelination of corpus callosum
0.000 0.323 0.677
G37.0 Diffuse sclerosis
0.000 0.323 0.677
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.396 0.603
E05.9 Thyrotoxicosis, unspecified
0.000 0.451 0.549
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.457 0.543
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.476 0.524
G36.0 Neuromyelitis optica [Devic]
0.000 0.490 0.510
G36.9 Acute disseminated demyelination, unspecified
0.000 0.501 0.498
G36.8 Other specified acute disseminated demyelination
0.000 0.501 0.498
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.501 0.498
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.513 0.487
E00-E07 Disorders of thyroid gland
0.000 0.550 0.450
E06 Thyroiditis
0.000 0.553 0.447
I84.9 Unspecified haemorrhoids without complication
0.445 0.555 0.000
E06.3 Autoimmune thyroiditis
0.000 0.570 0.430
E06.9 Thyroiditis, unspecified
0.000 0.583 0.417
E05.5 Thyroid crisis or storm
0.000 0.610 0.390
E05.4 Thyrotoxicosis factitia
0.000 0.610 0.390
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.610 0.390
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.610 0.390
E05.8 Other thyrotoxicosis
0.000 0.642 0.358
E06.5 Other chronic thyroiditis
0.000 0.658 0.342
E07 Other disorders of thyroid
0.000 0.660 0.340
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.677 0.323
E00 Congenital iodine-deficiency syndrome
0.000 0.677 0.323
E06.4 Drug-induced thyroiditis
0.000 0.679 0.321
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.679 0.321
E06.0 Acute thyroiditis
0.000 0.679 0.321
E03 Other hypothyroidism
0.000 0.683 0.317
K90 Intestinal malabsorption
0.000 0.686 0.314
E06.1 Subacute thyroiditis
0.000 0.689 0.311
E07.8 Other specified disorders of thyroid
0.000 0.724 0.276
E03.9 Hypothyroidism, unspecified
0.000 0.743 0.257
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.754 0.246
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.754 0.246
E07.1 Dyshormogenetic goitre
0.000 0.756 0.244
E07.0 Hypersecretion of calcitonin
0.000 0.756 0.244
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.768 0.231
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.768 0.231
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.768 0.231
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.768 0.231
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.768 0.231
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.768 0.231
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.768 0.231
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.768 0.231
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.772 0.228
K90.8 Other intestinal malabsorption
0.000 0.772 0.228
E03.5 Myxoedema coma
0.000 0.772 0.227
E03.4 Atrophy of thyroid (acquired)
0.000 0.772 0.227
E03.3 Postinfectious hypothyroidism
0.000 0.772 0.227
K90.3 Pancreatic steatorrhoea
0.000 0.775 0.225
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.775 0.225
K90.1 Tropical sprue
0.000 0.775 0.225
K90.9 Intestinal malabsorption, unspecified
0.000 0.777 0.223
E07.9 Disorder of thyroid, unspecified
0.000 0.779 0.221
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.792 0.208
E83 Disorders of mineral metabolism
0.000 0.797 0.203
E03.8 Other specified hypothyroidism
0.000 0.806 0.194
E03.1 Congenital hypothyroidism without goitre
0.000 0.812 0.187
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.839 0.161
S06.3 Focal brain injury
0.000 0.841 0.159
E83.8 Other disorders of mineral metabolism
0.000 0.854 0.145
E83.2 Disorders of zinc metabolism
0.000 0.854 0.145
E83.0 Disorders of copper metabolism
0.000 0.854 0.145
M35.0 Sicca syndrome [Sjogren]
0.000 0.856 0.144
E83.3 Disorders of phosphorus metabolism
0.000 0.863 0.137
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.864 0.136
E83.5 Disorders of calcium metabolism
0.000 0.874 0.126
S06 Intracranial injury
0.000 0.876 0.124
S06.5 Traumatic subdural haemorrhage
0.000 0.882 0.118
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.886 0.114
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.886 0.114
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.891 0.109
E89.0 Postprocedural hypothyroidism
0.000 0.896 0.104
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.902 0.098
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.902 0.098
E70-E90 Metabolic disorders
0.000 0.903 0.097
S06.1 Traumatic cerebral oedema
0.000 0.905 0.095
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.905 0.095
S06.9 Intracranial injury, unspecified
0.000 0.910 0.090
S06.7 Intracranial injury with prolonged coma
0.000 0.911 0.089
E89.2 Postprocedural hypoparathyroidism
0.000 0.915 0.085
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.915 0.085
S06.4 Epidural haemorrhage
0.000 0.917 0.083
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.921 0.079
E40-E46 Malnutrition
0.000 0.921 0.079
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.922 0.078
S06.2 Diffuse brain injury
0.000 0.922 0.078
S06.0 Concussion
0.000 0.923 0.077
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.000 0.926 0.074
S06.8 Other intracranial injuries
0.000 0.927 0.073
E89.4 Postprocedural ovarian failure
0.000 0.927 0.073
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.930 0.070
E89.1 Postprocedural hypoinsulinaemia
0.000 0.930 0.070
E77 Disorders of glycoprotein metabolism
0.000 0.930 0.070
E76 Disorders of glycosaminoglycan metabolism
0.000 0.930 0.070
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.930 0.070
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.930 0.070
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.931 0.069
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.000 0.932 0.068
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.932 0.068
E70 Disorders of aromatic amino-acid metabolism
0.000 0.932 0.068
E73 Lactose intolerance
0.000 0.932 0.068
E46 Unspecified protein-energy malnutrition
0.000 0.933 0.067
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.933 0.067
I71 Aortic aneurysm and dissection
0.000 0.934 0.066
E84 Cystic fibrosis
0.000 0.934 0.066
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.000 0.935 0.065
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.000 0.935 0.064
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.936 0.064
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.936 0.064
E74 Other disorders of carbohydrate metabolism
0.000 0.937 0.063
E72 Other disorders of amino-acid metabolism
0.000 0.938 0.062
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.940 0.060
E79 Disorders of purine and pyrimidine metabolism
0.000 0.940 0.060
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.940 0.060
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.940 0.060
E04 Other non-toxic goitre
0.000 0.942 0.058
E80.6 Other disorders of bilirubin metabolism
0.000 0.943 0.057
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.943 0.057
E45 Retarded development following protein-energy malnutrition
0.000 0.943 0.057
E43 Unspecified severe protein-energy malnutrition
0.000 0.943 0.057
E42 Marasmic kwashiorkor
0.000 0.943 0.057
E41 Nutritional marasmus
0.000 0.943 0.057
E40 Kwashiorkor
0.000 0.943 0.057
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.944 0.056
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.944 0.056
S06.01 Concussion (with open intracranial wound)
0.000 0.944 0.055
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.946 0.054
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.947 0.052
E89.5 Postprocedural testicular hypofunction
0.000 0.948 0.052
E75.5 Other lipid storage disorders
0.000 0.948 0.051
E80.1 Porphyria cutanea tarda
0.000 0.949 0.051
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.950 0.050
E71.3 Disorders of fatty-acid metabolism
0.000 0.950 0.050
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.950 0.050
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.950 0.050
E71.0 Maple-syrup-urine disease
0.000 0.950 0.050
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.950 0.050
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.950 0.050
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.950 0.050
E76.2 Other mucopolysaccharidoses
0.000 0.950 0.050
E76.1 Mucopolysaccharidosis, type II
0.000 0.950 0.050
E76.0 Mucopolysaccharidosis, type I
0.000 0.950 0.050
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.950 0.050
E77.8 Other disorders of glycoprotein metabolism
0.000 0.950 0.050
E77.1 Defects in glycoprotein degradation
0.000 0.950 0.050
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.950 0.050
E84.9 Cystic fibrosis, unspecified
0.000 0.950 0.050
E75.6 Lipid storage disorder, unspecified
0.000 0.951 0.049
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.951 0.049
E75.3 Sphingolipidosis, unspecified
0.000 0.951 0.049
E75.1 Other gangliosidosis
0.000 0.951 0.049
E75.0 GM2 gangliosidosis
0.000 0.951 0.049
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.951 0.049
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.951 0.049
E70.2 Disorders of tyrosine metabolism
0.000 0.951 0.049
E70.1 Other hyperphenylalaninaemias
0.000 0.951 0.049
E70.0 Classical phenylketonuria
0.000 0.951 0.049
E73.8 Other lactose intolerance
0.000 0.951 0.049
E73.1 Secondary lactase deficiency
0.000 0.951 0.049
E73.0 Congenital lactase deficiency
0.000 0.951 0.049
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.952 0.048
E80.5 Crigler-Najjar syndrome
0.000 0.952 0.048
E80.3 Defects of catalase and peroxydase
0.000 0.952 0.048
E80.0 Hereditary erythropoietic porphyria
0.000 0.952 0.048
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.952 0.048
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.952 0.048
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.952 0.048
E84.8 Cystic fibrosis with other manifestations
0.000 0.952 0.048
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.952 0.048
I72 Other aneurysm
0.000 0.953 0.047
E88 Other metabolic disorders
0.000 0.953 0.047
E70.3 Albinism
0.000 0.953 0.047
E73.9 Lactose intolerance, unspecified
0.000 0.953 0.046
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.954 0.046
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.954 0.045
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.954 0.045
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.954 0.045
E74.2 Disorders of galactose metabolism
0.000 0.954 0.045
E74.1 Disorders of fructose metabolism
0.000 0.954 0.045
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.955 0.045
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.955 0.045
E72.5 Disorders of glycine metabolism
0.000 0.955 0.045
E72.4 Disorders of ornithine metabolism
0.000 0.955 0.045
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.955 0.045
E72.2 Disorders of urea cycle metabolism
0.000 0.955 0.045
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.955 0.045
I72.4 Aneurysm of artery of lower extremity
0.000 0.955 0.045
E74.0 Glycogen storage disease
0.000 0.956 0.044
I73 Other peripheral vascular diseases
0.000 0.956 0.044
E72.0 Disorders of amino-acid transport
0.000 0.956 0.044
E75.2 Other sphingolipidosis
0.000 0.956 0.044
S06.00 Concussion (without open intracranial wound)
0.000 0.956 0.044
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.956 0.044
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.957 0.043
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.957 0.043
E79.1 Lesch-Nyhan syndrome
0.000 0.957 0.043
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.957 0.043
E04.0 Non-toxic diffuse goitre
0.000 0.957 0.043
I73.9 Peripheral vascular disease, unspecified
0.000 0.958 0.042
E80.2 Other porphyria
0.000 0.958 0.042
E04.8 Other specified non-toxic goitre
0.000 0.958 0.042
E89.3 Postprocedural hypopituitarism
0.000 0.958 0.041
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.959 0.041
E44.1 Mild protein-energy malnutrition
0.000 0.959 0.041
E44.0 Moderate protein-energy malnutrition
0.000 0.959 0.041
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.960 0.040
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.961 0.039
I74 Arterial embolism and thrombosis
0.000 0.961 0.039
I71.0 Dissection of aorta [any part]
0.000 0.961 0.039
I72.9 Aneurysm of unspecified site
0.000 0.961 0.039
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.961 0.039
I72.1 Aneurysm of artery of upper extremity
0.000 0.962 0.038
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.962 0.038
I70 Atherosclerosis
0.000 0.963 0.037
E86 Volume depletion
0.000 0.963 0.037
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.964 0.036
E88.9 Metabolic disorder, unspecified
0.000 0.964 0.036
I72.8 Aneurysm of other specified arteries
0.000 0.964 0.036
I74.8 Embolism and thrombosis of other arteries
0.000 0.965 0.035
E65-E68 Obesity and other hyperalimentation
0.000 0.965 0.035
E15 Nondiabetic hypoglycaemic coma
0.000 0.965 0.035
M35 Other systemic involvement of connective tissue
0.000 0.965 0.035
E88.2 Lipomatosis, not elsewhere classified
0.000 0.965 0.034
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.966 0.034
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.966 0.034
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.966 0.034
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.966 0.034
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.966 0.034
I72.2 Aneurysm of renal artery
0.000 0.967 0.033
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.967 0.032
E80.4 Gilbert's syndrome
0.000 0.968 0.032
E88.3 Tumour lysis syndrome
0.000 0.968 0.032
I70.8 Atherosclerosis of other arteries
0.000 0.969 0.031
I72.3 Aneurysm of iliac artery
0.000 0.969 0.031
I79.1 Aortitis in diseases classified elsewhere
0.000 0.969 0.031
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.969 0.031
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.969 0.031
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.969 0.031
M35.7 Hypermobility syndrome
0.000 0.970 0.030
E83.4 Disorders of magnesium metabolism
0.000 0.970 0.030
I73.8 Other specified peripheral vascular diseases
0.000 0.970 0.030
E88.8 Other specified metabolic disorders
0.000 0.971 0.029
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.971 0.029
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.971 0.029
E85 Amyloidosis
0.001 0.972 0.027
I72.0 Aneurysm of carotid artery
0.000 0.972 0.028
I70.1 Atherosclerosis of renal artery
0.000 0.973 0.027
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.973 0.027
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.973 0.027
I70.9 Generalised and unspecified atherosclerosis
0.000 0.974 0.026
I70.0 Atherosclerosis of aorta
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.974 0.026
E67 Other hyperalimentation
0.000 0.975 0.025
E68 Sequelae of hyperalimentation
0.000 0.975 0.025
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.975 0.025
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.975 0.025
M35.5 Multifocal fibrosclerosis
0.000 0.975 0.025
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.975 0.025
K50.9 Crohn's disease, unspecified
0.025 0.975 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.976 0.024
E50-E64 Other nutritional deficiencies
0.000 0.976 0.024
I77 Other disorders of arteries and arterioles
0.000 0.976 0.024
M35.1 Other overlap syndromes
0.000 0.977 0.023
E27.1 Primary adrenocortical insufficiency
0.000 0.977 0.023
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.977 0.023
M35.2 Behcet's disease
0.000 0.977 0.023
M35.8 Other specified systemic involvement of connective tissue
0.000 0.977 0.022
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.978 0.022
I77.2 Rupture of artery
0.000 0.978 0.022
E20-E35 Disorders of other endocrine glands
0.000 0.978 0.022
R31 Unspecified haematuria
0.021 0.979 0.000
E85.8 Other amyloidosis
0.001 0.979 0.020
E04.9 Non-toxic goitre, unspecified
0.000 0.979 0.021
E65 Localised adiposity
0.000 0.979 0.021
I73.0 Raynaud's syndrome
0.000 0.979 0.021
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.979 0.021
E85.2 Heredofamilial amyloidosis, unspecified
0.001 0.979 0.020
E85.1 Neuropathic heredofamilial amyloidosis
0.001 0.979 0.020
E85.0 Nonneuropathic heredofamilial amyloidosis
0.001 0.979 0.020
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.980 0.020
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.980 0.020
E27 Other disorders of adrenal gland
0.000 0.980 0.020
K50 Crohn's disease [regional enteritis]
0.019 0.981 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.981 0.019
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.981 0.019
E20 Hypoparathyroidism
0.000 0.981 0.019
E51 Thiamine deficiency
0.000 0.981 0.019
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.018
E67.8 Other specified hyperalimentation
0.000 0.982 0.018
E67.3 Hypervitaminosis D
0.000 0.982 0.018
E67.2 Megavitamin-B6 syndrome
0.000 0.982 0.018
E67.1 Hypercarotenaemia
0.000 0.982 0.018
E67.0 Hypervitaminosis A
0.000 0.982 0.018
I77.8 Other specified disorders of arteries and arterioles
0.000 0.982 0.018
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.982 0.018
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.982 0.018
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.982 0.018
K50.8 Other Crohn's disease
0.018 0.982 0.000
E25 Adrenogenital disorders
0.000 0.982 0.018
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.982 0.017
E63 Other nutritional deficiencies
0.000 0.982 0.017
E50 Vitamin A deficiency
0.000 0.982 0.017
E60 Dietary zinc deficiency
0.000 0.982 0.017
E59 Dietary selenium deficiency
0.000 0.982 0.017
E52 Niacin deficiency [pellagra]
0.000 0.982 0.017
E56 Other vitamin deficiencies
0.000 0.983 0.017
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.983 0.017
I77.5 Necrosis of artery
0.000 0.983 0.017
I77.4 Coeliac artery compression syndrome
0.000 0.983 0.017
I77.3 Arterial fibromuscular dysplasia
0.000 0.983 0.017
K51.2 Ulcerative (chronic) proctitis
0.017 0.983 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.983 0.017
E20.9 Hypoparathyroidism, unspecified
0.000 0.983 0.017
E85.3 Secondary systemic amyloidosis
0.001 0.983 0.015
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.984 0.016
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.984 0.016
E32 Diseases of thymus
0.000 0.984 0.016
E31 Polyglandular dysfunction
0.000 0.984 0.016
E30 Disorders of puberty, not elsewhere classified
0.000 0.984 0.016
E54 Ascorbic acid deficiency
0.000 0.984 0.015
E58 Dietary calcium deficiency
0.000 0.984 0.015
K51 Ulcerative colitis
0.016 0.984 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.985 0.015
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.985 0.015
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.985 0.015
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.985 0.015
E51.2 Wernicke's encephalopathy
0.000 0.985 0.015
E16 Other disorders of pancreatic internal secretion
0.000 0.985 0.015
E23.6 Other disorders of pituitary gland
0.000 0.985 0.015
E27.5 Adrenomedullary hyperfunction
0.000 0.986 0.014
E27.0 Other adrenocortical overactivity
0.000 0.986 0.014
E04.2 Non-toxic multinodular goitre
0.000 0.986 0.014
K51.0 Ulcerative (chronic) enterocolitis
0.014 0.986 0.000
E26 Hyperaldosteronism
0.000 0.986 0.014
E55 Vitamin D deficiency
0.000 0.986 0.014
K50-K52 Noninfective enteritis and colitis
0.014 0.986 0.000
I78 Diseases of capillaries
0.000 0.986 0.014
E20.8 Other hypoparathyroidism
0.000 0.986 0.014
E20.1 Pseudohypoparathyroidism
0.000 0.986 0.014
E20.0 Idiopathic hypoparathyroidism
0.000 0.986 0.014
E51.9 Thiamine deficiency, unspecified
0.000 0.986 0.013
E51.8 Other manifestations of thiamine deficiency
0.000 0.986 0.013
E51.1 Beriberi
0.000 0.986 0.013
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.013
E29 Testicular dysfunction
0.000 0.986 0.013
I77.6 Arteritis, unspecified
0.000 0.987 0.013
E23.7 Disorder of pituitary gland, unspecified
0.000 0.987 0.013
E25.9 Adrenogenital disorder, unspecified
0.000 0.987 0.013
E25.8 Other adrenogenital disorders
0.000 0.987 0.013
E78.4 Other hyperlipidaemia
0.000 0.987 0.013
E50.9 Vitamin A deficiency, unspecified
0.000 0.987 0.013
E50.8 Other manifestations of vitamin A deficiency
0.000 0.987 0.013
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.987 0.013
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.987 0.013
E50.5 Vitamin A deficiency with night blindness
0.000 0.987 0.013
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.987 0.013
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.987 0.013
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.987 0.013
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.987 0.013
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.987 0.013
E63.9 Nutritional deficiency, unspecified
0.000 0.987 0.013
E63.8 Other specified nutritional deficiencies
0.000 0.987 0.013
E63.1 Imbalance of constituents of food intake
0.000 0.987 0.013
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.987 0.013
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.987 0.013
E64.8 Sequelae of other nutritional deficiencies
0.000 0.987 0.013
E64.3 Sequelae of rickets
0.000 0.987 0.013
E64.2 Sequelae of vitamin C deficiency
0.000 0.987 0.013
E64.1 Sequelae of vitamin A deficiency
0.000 0.987 0.013
E64.0 Sequelae of protein-energy malnutrition
0.000 0.987 0.013
E85.4 Organ-limited amyloidosis
0.001 0.987 0.011
A08.4 Viral intestinal infection, unspecified
0.000 0.987 0.013
K50.1 Crohn's disease of large intestine
0.013 0.987 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.987 0.012
E56.8 Deficiency of other vitamins
0.000 0.987 0.012
E56.0 Deficiency of vitamin E
0.000 0.987 0.012
E27.2 Addisonian crisis
0.000 0.987 0.012
E53 Deficiency of other B group vitamins
0.000 0.987 0.013
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.987 0.013
E56.1 Deficiency of vitamin K
0.000 0.987 0.012
E78.6 Lipoprotein deficiency
0.000 0.987 0.012
B37.9 Candidiasis, unspecified
0.000 0.988 0.012
K51.1 Ulcerative (chronic) ileocolitis
0.012 0.988 0.000
E78.3 Hyperchylomicronaemia
0.000 0.988 0.012
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.988 0.012
E23.1 Drug-induced hypopituitarism
0.000 0.988 0.012
I77.0 Arteriovenous fistula, acquired
0.000 0.988 0.012
K51.8 Other ulcerative colitis
0.012 0.988 0.000
E34 Other endocrine disorders
0.000 0.988 0.012
K51.5 Mucosal proctocolitis
0.012 0.988 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.988 0.011
E30.8 Other disorders of puberty
0.000 0.988 0.011
E30.1 Precocious puberty
0.000 0.988 0.011
E30.0 Delayed puberty
0.000 0.988 0.011
E31.9 Polyglandular dysfunction, unspecified
0.000 0.988 0.011
E31.8 Other polyglandular dysfunction
0.000 0.988 0.011
E31.1 Polyglandular hyperfunction
0.000 0.988 0.011
E31.0 Autoimmune polyglandular failure
0.000 0.988 0.011
E32.9 Disease of thymus, unspecified
0.000 0.988 0.011
E32.8 Other diseases of thymus
0.000 0.988 0.011
E32.1 Abscess of thymus
0.000 0.988 0.011
E32.0 Persistent hyperplasia of thymus
0.000 0.988 0.011
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.988 0.011
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.988 0.011
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.988 0.011
N76 Other inflammation of vagina and vulva
0.000 0.988 0.012
I74.5 Embolism and thrombosis of iliac artery
0.000 0.989 0.011
E27.9 Disorder of adrenal gland, unspecified
0.000 0.989 0.011
E78.1 Pure hyperglyceridaemia
0.000 0.989 0.011
B37 Candidiasis
0.000 0.989 0.011
E23.2 Diabetes insipidus
0.000 0.989 0.011
K51.4 Pseudopolyposis of colon
0.011 0.989 0.000
N76.8 Other specified inflammation of vagina and vulva
0.000 0.989 0.011
N76.2 Acute vulvitis
0.000 0.989 0.011
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.989 0.011
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.989 0.011
E16.4 Abnormal secretion of gastrin
0.000 0.989 0.011
E16.3 Increased secretion of glucagon
0.000 0.989 0.011
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.008 0.989 0.003
N76.3 Subacute and chronic vulvitis
0.000 0.989 0.011
E24 Cushing's syndrome
0.000 0.989 0.011
B37.3 Candidiasis of vulva and vagina
0.000 0.989 0.011
G60.0 Hereditary motor and sensory neuropathy
0.010 0.989 0.000
E85.9 Amyloidosis, unspecified
0.002 0.989 0.009
N76.4 Abscess of vulva
0.000 0.990 0.010
B37.8 Candidiasis of other sites
0.000 0.990 0.010
E26.8 Other hyperaldosteronism
0.000 0.990 0.010
E26.1 Secondary hyperaldosteronism
0.000 0.990 0.010
E55.0 Rickets, active
0.000 0.990 0.010
G61 Inflammatory polyneuropathy
0.010 0.990 0.001
B37.0 Candidal stomatitis
0.000 0.990 0.010
G61.0 Guillain-Barre syndrome
0.010 0.990 0.000
E10-E14 Diabetes mellitus
0.000 0.990 0.010
G60 Hereditary and idiopathic neuropathy
0.009 0.990 0.001
E29.8 Other testicular dysfunction
0.000 0.990 0.010
E29.0 Testicular hyperfunction
0.000 0.990 0.010
E26.9 Hyperaldosteronism, unspecified
0.000 0.990 0.010
N76.0 Acute vaginitis
0.000 0.990 0.010
E61 Deficiency of other nutrient elements
0.000 0.990 0.010
E28 Ovarian dysfunction
0.000 0.990 0.009
G63 Polyneuropathy in diseases classified elsewhere
0.008 0.990 0.001
I31.3 Pericardial effusion (noninflammatory)
0.000 0.991 0.009
M35.3 Polymyalgia rheumatica
0.000 0.991 0.009
E29.9 Testicular dysfunction, unspecified
0.000 0.991 0.009
E53.1 Pyridoxine deficiency
0.000 0.991 0.009
E53.0 Riboflavin deficiency
0.000 0.991 0.009
E78.2 Mixed hyperlipidaemia
0.000 0.991 0.009
E34.9 Endocrine disorder, unspecified
0.000 0.991 0.009
I78.9 Disease of capillaries, unspecified
0.000 0.991 0.009
E23.0 Hypopituitarism
0.000 0.991 0.009
K51.9 Ulcerative colitis, unspecified
0.009 0.991 0.000
E26.0 Primary hyperaldosteronism
0.000 0.991 0.009
B37.7 Candidal septicaemia
0.000 0.991 0.009
N76.1 Subacute and chronic vaginitis
0.000 0.991 0.009
E34.5 Androgen resistance syndrome
0.000 0.991 0.009
E34.4 Constitutional tall stature
0.000 0.991 0.009
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.991 0.009
E34.1 Other hypersecretion of intestinal hormones
0.000 0.991 0.009
N76.5 Ulceration of vagina
0.000 0.991 0.009
E53.9 Vitamin B deficiency, unspecified
0.000 0.991 0.009
G63.2 Diabetic polyneuropathy
0.009 0.991 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.991 0.009
G61.8 Other inflammatory polyneuropathies
0.008 0.991 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.992 0.008
E34.0 Carcinoid syndrome
0.000 0.992 0.008
E29.1 Testicular hypofunction
0.000 0.992 0.008
E34.3 Short stature, not elsewhere classified
0.000 0.992 0.008
B37.6 Candidal endocarditis
0.000 0.992 0.008
B37.5 Candidal meningitis
0.000 0.992 0.008
E22 Hyperfunction of pituitary gland
0.000 0.992 0.008
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.992 0.008
G61.9 Inflammatory polyneuropathy, unspecified
0.008 0.992 0.000
G64 Other disorders of peripheral nervous system
0.006 0.992 0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.992 0.008
E24.3 Ectopic ACTH syndrome
0.000 0.992 0.008
E24.1 Nelson's syndrome
0.000 0.992 0.008
E16.1 Other hypoglycaemia
0.000 0.992 0.008
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.992 0.008
I78.8 Other diseases of capillaries
0.000 0.992 0.008
K50.0 Crohn's disease of small intestine
0.008 0.992 0.000
E24.2 Drug-induced Cushing's syndrome
0.000 0.992 0.007
G61.1 Serum neuropathy
0.007 0.992 0.001
E04.1 Non-toxic single thyroid nodule
0.000 0.992 0.007
E13 Other specified diabetes mellitus
0.000 0.992 0.007
B37.2 Candidiasis of skin and nail
0.000 0.992 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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