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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3873374
log Bayes Factor = 44.0138
Chromosome 6   position 31,251,311  (GRCh37) Explore rs3873374 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.006 0.994
M45 Ankylosing spondylitis
0.000 0.035 0.965
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.058 0.942
L40.0 Psoriasis vulgaris
0.000 0.067 0.933
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.108 0.892
L40.8 Other psoriasis
0.000 0.216 0.784
L40.3 Pustulosis palmaris et plantaris
0.000 0.246 0.754
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.308 0.692
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.308 0.692
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.308 0.692
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.308 0.692
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.308 0.692
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.308 0.692
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.308 0.692
E03 Other hypothyroidism
0.000 0.370 0.630
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.383 0.617
M07.3 Other psoriatic arthropathies
0.000 0.406 0.594
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.415 0.585
E03.8 Other specified hypothyroidism
0.000 0.459 0.541
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.470 0.530
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.541 0.459
E03.5 Myxoedema coma
0.000 0.548 0.452
E03.4 Atrophy of thyroid (acquired)
0.000 0.548 0.452
E03.3 Postinfectious hypothyroidism
0.000 0.548 0.452
M07.38 Other psoriatic arthropathies (Other)
0.000 0.574 0.426
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.574 0.426
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.574 0.426
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.574 0.426
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.574 0.426
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.574 0.426
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.581 0.419
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.590 0.410
E03.1 Congenital hypothyroidism without goitre
0.000 0.604 0.396
G35 Multiple sclerosis
0.000 0.620 0.380
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.693 0.307
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.698 0.302
G30-G32 Other degenerative diseases of the nervous system
0.000 0.700 0.300
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.704 0.296
Chapter VI Diseases of the nervous system
0.000 0.721 0.279
G31.2 Degeneration of nervous system due to alcohol
0.000 0.723 0.277
G31.8 Other specified degenerative diseases of nervous system
0.000 0.726 0.274
G30 Alzheimer's disease
0.000 0.728 0.272
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.740 0.260
K90 Intestinal malabsorption
0.000 0.741 0.259
M07 Psoriatic and enteropathic arthropathies
0.001 0.747 0.252
G31.0 Circumscribed brain atrophy
0.000 0.750 0.250
G30.9 Alzheimer's disease, unspecified
0.000 0.754 0.246
G62 Other polyneuropathies
0.000 0.759 0.241
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.762 0.238
G62.9 Polyneuropathy, unspecified
0.000 0.767 0.233
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.770 0.230
G70-G73 Diseases of myoneural junction and muscle
0.000 0.780 0.220
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.780 0.220
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.782 0.218
L40-L45 Papulosquamous disorders
0.000 0.782 0.218
G30.1 Alzheimer's disease with late onset
0.000 0.790 0.210
G61 Inflammatory polyneuropathy
0.000 0.797 0.203
G30.0 Alzheimer's disease with early onset
0.000 0.798 0.202
G36 Other acute disseminated demyelination
0.000 0.798 0.202
G83 Other paralytic syndromes
0.000 0.800 0.200
G60 Hereditary and idiopathic neuropathy
0.000 0.801 0.199
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.802 0.198
G03 Meningitis due to other and unspecified causes
0.000 0.806 0.194
G30.8 Other Alzheimer's disease
0.000 0.809 0.191
G62.1 Alcoholic polyneuropathy
0.000 0.809 0.191
G00 Bacterial meningitis, not elsewhere classified
0.000 0.810 0.190
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.811 0.189
G83.4 Cauda equina syndrome
0.000 0.812 0.188
G64 Other disorders of peripheral nervous system
0.000 0.814 0.186
K90.3 Pancreatic steatorrhoea
0.000 0.814 0.186
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.814 0.186
K90.1 Tropical sprue
0.000 0.814 0.186
M07.6 Other enteropathic arthropathies
0.001 0.818 0.181
M07.5 Arthropathy in ulcerative colitis
0.001 0.818 0.181
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.818 0.181
M07.2 Psoriatic spondylitis
0.001 0.818 0.181
M07.1 Arthritis mutilans
0.001 0.818 0.181
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.818 0.181
K90.8 Other intestinal malabsorption
0.000 0.819 0.181
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.820 0.180
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.821 0.179
G71 Primary disorders of muscles
0.000 0.822 0.178
G61.8 Other inflammatory polyneuropathies
0.000 0.823 0.177
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.826 0.174
G62.2 Polyneuropathy due to other toxic agents
0.000 0.827 0.173
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.828 0.172
G83.9 Paralytic syndrome, unspecified
0.000 0.828 0.172
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.829 0.171
G60.0 Hereditary motor and sensory neuropathy
0.000 0.834 0.166
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.835 0.165
G62.8 Other specified polyneuropathies
0.000 0.837 0.163
G03.9 Meningitis, unspecified
0.000 0.838 0.162
G72 Other myopathies
0.000 0.840 0.160
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.841 0.159
G06.1 Intraspinal abscess and granuloma
0.000 0.841 0.159
G06.0 Intracranial abscess and granuloma
0.000 0.841 0.159
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.842 0.158
G70 Myasthenia gravis and other myoneural disorders
0.000 0.843 0.157
L44 Other papulosquamous disorders
0.000 0.843 0.156
L41 Parapsoriasis
0.000 0.843 0.156
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.843 0.156
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.846 0.154
G00.1 Pneumococcal meningitis
0.000 0.846 0.154
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.846 0.153
L42 Pityriasis rosea
0.000 0.849 0.151
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.849 0.151
G81 Hemiplegia
0.000 0.849 0.151
K90.9 Intestinal malabsorption, unspecified
0.000 0.850 0.150
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.852 0.148
G83.1 Monoplegia of lower limb
0.000 0.852 0.148
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.853 0.147
G61.1 Serum neuropathy
0.000 0.854 0.146
G36.9 Acute disseminated demyelination, unspecified
0.000 0.855 0.145
G36.8 Other specified acute disseminated demyelination
0.000 0.855 0.145
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.855 0.145
G83.5 Locked-in syndrome
0.000 0.856 0.144
G83.3 Monoplegia, unspecified
0.000 0.856 0.144
G83.0 Diplegia of upper limbs
0.000 0.856 0.144
G60.3 Idiopathic progressive neuropathy
0.000 0.857 0.143
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.857 0.143
G60.1 Refsum's disease
0.000 0.857 0.143
G00.9 Bacterial meningitis, unspecified
0.000 0.860 0.140
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.860 0.139
G03.8 Meningitis due to other specified causes
0.000 0.861 0.139
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.861 0.139
G03.1 Chronic meningitis
0.000 0.861 0.139
G03.0 Nonpyogenic meningitis
0.000 0.861 0.139
G06.2 Extradural and subdural abscess, unspecified
0.000 0.862 0.138
G00.8 Other bacterial meningitis
0.000 0.863 0.136
G00.3 Staphylococcal meningitis
0.000 0.863 0.136
G00.2 Streptococcal meningitis
0.000 0.863 0.136
G00.0 Haemophilus meningitis
0.000 0.863 0.136
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.863 0.136
G61.0 Guillain-Barre syndrome
0.000 0.866 0.134
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.870 0.130
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.870 0.130
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.870 0.130
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.870 0.130
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.870 0.130
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.870 0.130
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.870 0.130
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.870 0.130
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.870 0.130
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.870 0.130
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.870 0.130
M07.18 Arthritis mutilans (Other)
0.001 0.870 0.130
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.870 0.130
M07.16 Arthritis mutilans (Lower leg)
0.001 0.870 0.130
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.870 0.130
M07.14 Arthritis mutilans (Hand)
0.001 0.870 0.130
M07.13 Arthritis mutilans (Forearm)
0.001 0.870 0.130
M07.12 Arthritis mutilans (Upper arm)
0.001 0.870 0.130
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.870 0.130
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.870 0.130
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.870 0.130
M07.28 Psoriatic spondylitis (Other)
0.001 0.870 0.130
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.870 0.130
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.870 0.130
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.870 0.130
M07.24 Psoriatic spondylitis (Hand)
0.001 0.870 0.130
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.870 0.130
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.870 0.130
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.870 0.130
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.870 0.130
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.870 0.130
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.870 0.130
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.870 0.130
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.870 0.130
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.870 0.130
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.870 0.130
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.870 0.130
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.870 0.130
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.870 0.130
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.870 0.130
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.870 0.130
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.870 0.130
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.870 0.130
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.870 0.130
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.870 0.130
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.870 0.130
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.870 0.130
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.870 0.130
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.870 0.130
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.870 0.130
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.870 0.130
M07.68 Other enteropathic arthropathies (Other)
0.001 0.870 0.130
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.870 0.130
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.870 0.130
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.870 0.130
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.870 0.130
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.870 0.130
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.870 0.130
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.870 0.130
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.870 0.130
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.870 0.130
G36.0 Neuromyelitis optica [Devic]
0.000 0.870 0.130
G83.8 Other specified paralytic syndromes
0.000 0.871 0.129
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.871 0.128
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.871 0.128
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.871 0.128
G62.0 Drug-induced polyneuropathy
0.000 0.871 0.128
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.872 0.128
G71.9 Primary disorder of muscle, unspecified
0.000 0.872 0.128
G71.8 Other primary disorders of muscles
0.000 0.872 0.128
G71.2 Congenital myopathies
0.000 0.872 0.128
G71.1 Myotonic disorders
0.000 0.873 0.127
G37 Other demyelinating diseases of central nervous system
0.000 0.873 0.126
G82 Paraplegia and tetraplegia
0.000 0.873 0.127
G12 Spinal muscular atrophy and related syndromes
0.000 0.874 0.126
G80 Infantile cerebral palsy
0.000 0.874 0.126
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.875 0.125
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.875 0.125
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.875 0.125
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.875 0.125
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.875 0.125
G63.1 Polyneuropathy in neoplastic disease
0.000 0.875 0.125
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.875 0.125
G81.1 Spastic hemiplegia
0.000 0.876 0.123
G72.9 Myopathy, unspecified
0.000 0.879 0.121
G70.0 Myasthenia gravis
0.000 0.879 0.121
G72.8 Other specified myopathies
0.000 0.884 0.116
G72.0 Drug-induced myopathy
0.000 0.885 0.115
G72.3 Periodic paralysis
0.000 0.885 0.115
G72.2 Myopathy due to other toxic agents
0.000 0.885 0.115
G72.1 Alcoholic myopathy
0.000 0.885 0.115
G71.0 Muscular dystrophy
0.000 0.886 0.114
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.886 0.114
G73.7 Myopathy other diseases classified elsewhere
0.000 0.886 0.113
G73.6 Myopathy in metabolic diseases
0.000 0.886 0.113
G73.5 Myopathy in endocrine diseases
0.000 0.886 0.113
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.886 0.113
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.886 0.113
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.886 0.113
G73.1 Eaton-Lambert syndrome
0.000 0.886 0.113
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.886 0.113
G70.8 Other specified myoneural disorders
0.000 0.887 0.113
G70.2 Congenital and developmental myasthenia
0.000 0.887 0.113
G70.1 Toxic myoneural disorders
0.000 0.887 0.113
L41.9 Parapsoriasis, unspecified
0.000 0.887 0.112
L41.8 Other parapsoriasis
0.000 0.887 0.112
L41.5 Retiform parapsoriasis
0.000 0.887 0.112
L41.4 Large plaque parapsoriasis
0.000 0.887 0.112
L41.3 Small plaque parapsoriasis
0.000 0.887 0.112
L41.2 Lymphomatoid papulosis
0.000 0.887 0.112
L41.1 Pityriasis lichenoides chronica
0.000 0.887 0.112
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.887 0.112
L44.9 Papulosquamous disorder, unspecified
0.000 0.887 0.112
L44.8 Other specified papulosquamous disorders
0.000 0.887 0.112
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.887 0.112
L44.3 Lichen ruber moniliformis
0.000 0.887 0.112
L44.2 Lichen striatus
0.000 0.887 0.112
L44.1 Lichen nitidus
0.000 0.887 0.112
L44.0 Pityriasis rubra pilaris
0.000 0.887 0.112
G63.2 Diabetic polyneuropathy
0.000 0.888 0.112
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.889 0.111
D64.9 Anaemia, unspecified
0.000 0.891 0.109
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.891 0.108
G02.1 Meningitis in mycoses
0.000 0.891 0.108
G81.0 Flaccid hemiplegia
0.000 0.892 0.108
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.893 0.106
G04.1 Tropical spastic paraplegia
0.000 0.893 0.106
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.894 0.106
G11 Hereditary ataxia
0.000 0.895 0.105
G83.2 Monoplegia of upper limb
0.000 0.895 0.104
D64 Other anaemias
0.000 0.896 0.104
G82.1 Spastic paraplegia
0.000 0.897 0.103
G12.2 Motor neuron disease
0.000 0.897 0.103
G70.9 Myoneural disorder, unspecified
0.000 0.898 0.101
G14 Postpolio syndrome
0.000 0.900 0.099
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.901 0.099
D50 Iron deficiency anaemia
0.000 0.903 0.097
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.903 0.097
D50.9 Iron deficiency anaemia, unspecified
0.000 0.904 0.096
D60-D64 Aplastic and other anaemias
0.000 0.904 0.096
D50-D53 Nutritional anaemias
0.000 0.904 0.096
G80.2 Infantile hemiplegia
0.000 0.904 0.096
G80.0 Spastic cerebral palsy
0.000 0.906 0.094
D61 Other aplastic anaemias
0.000 0.908 0.092
G37.5 Concentric sclerosis [Balo]
0.000 0.909 0.091
G37.4 Subacute necrotising myelitis
0.000 0.909 0.091
G37.2 Central pontine myelinolysis
0.000 0.909 0.091
G37.1 Central demyelination of corpus callosum
0.000 0.909 0.091
G37.0 Diffuse sclerosis
0.000 0.909 0.091
D61.9 Aplastic anaemia, unspecified
0.000 0.909 0.091
G82.3 Flaccid tetraplegia
0.000 0.909 0.091
G82.0 Flaccid paraplegia
0.000 0.909 0.091
G12.9 Spinal muscular atrophy, unspecified
0.000 0.909 0.091
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.909 0.091
G12.1 Other inherited spinal muscular atrophy
0.000 0.909 0.091
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.909 0.091
G80.8 Other infantile cerebral palsy
0.000 0.909 0.091
G80.4 Ataxic cerebral palsy
0.000 0.909 0.091
G80.3 Dyskinetic cerebral palsy
0.000 0.909 0.091
D64.8 Other specified anaemias
0.000 0.910 0.090
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.911 0.089
N39.3 Stress incontinence
0.089 0.911 0.000
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.911 0.089
G82.4 Spastic tetraplegia
0.000 0.912 0.088
D50.8 Other iron deficiency anaemias
0.000 0.912 0.088
G82.5 Tetraplegia, unspecified
0.000 0.913 0.087
G04.0 Acute disseminated encephalitis
0.000 0.913 0.086
G10 Huntington's disease
0.000 0.914 0.085
D51 Vitamin B12 deficiency anaemia
0.000 0.917 0.083
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.918 0.082
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.918 0.082
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.918 0.082
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.918 0.082
D80-D89 Certain disorders involving the immune mechanism
0.000 0.919 0.081
G11.4 Hereditary spastic paraplegia
0.000 0.919 0.080
G80.1 Spastic diplegia
0.000 0.920 0.080
D52 Folate deficiency anaemia
0.000 0.921 0.079
M45-M49 Spondylopathies
0.000 0.922 0.077
G20-G26 Extrapyramidal and movement disorders
0.000 0.923 0.077
G11.8 Other hereditary ataxias
0.000 0.924 0.075
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.924 0.075
G11.2 Late-onset cerebellar ataxia
0.000 0.924 0.075
G11.0 Congenital nonprogressive ataxia
0.000 0.924 0.075
G81.9 Hemiplegia, unspecified
0.000 0.925 0.075
D64.4 Congenital dyserythropoietic anaemia
0.000 0.925 0.075
D64.3 Other sideroblastic anaemias
0.000 0.925 0.075
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.925 0.075
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.925 0.075
D64.0 Hereditary sideroblastic anaemia
0.000 0.925 0.075
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.926 0.074
K75 Other inflammatory liver diseases
0.000 0.927 0.073
D80 Immunodeficiency with predominantly antibody defects
0.000 0.927 0.073
K75.8 Other specified inflammatory liver diseases
0.000 0.929 0.071
D53 Other nutritional anaemias
0.000 0.929 0.071
D50.1 Sideropenic dysphagia
0.000 0.930 0.070
G11.1 Early-onset cerebellar ataxia
0.000 0.930 0.069
K75.4 Autoimmune hepatitis
0.000 0.931 0.069
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.931 0.069
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.931 0.069
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.931 0.069
K70 Alcoholic liver disease
0.000 0.931 0.069
K70-K77 Diseases of liver
0.000 0.932 0.068
K75.0 Abscess of liver
0.000 0.933 0.067
D52.9 Folate deficiency anaemia, unspecified
0.000 0.933 0.067
G11.9 Hereditary ataxia, unspecified
0.000 0.933 0.066
D61.8 Other specified aplastic anaemias
0.000 0.934 0.066
D61.3 Idiopathic aplastic anaemia
0.000 0.934 0.066
D61.2 Aplastic anaemia due to other external agents
0.000 0.934 0.066
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.934 0.066
K70.1 Alcoholic hepatitis
0.000 0.937 0.063
K72 Hepatic failure, not elsewhere classified
0.000 0.937 0.063
L43 Lichen planus
0.001 0.937 0.062
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.937 0.063
K73 Chronic hepatitis, not elsewhere classified
0.000 0.937 0.063
D61.0 Constitutional aplastic anaemia
0.000 0.938 0.062
G80.9 Infantile cerebral palsy, unspecified
0.000 0.938 0.062
R31 Unspecified haematuria
0.062 0.938 0.000
G90-G99 Other disorders of the nervous system
0.000 0.938 0.062
K70.4 Alcoholic hepatic failure
0.000 0.939 0.061
D86 Sarcoidosis
0.000 0.939 0.061
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.939 0.060
K70.0 Alcoholic fatty liver
0.000 0.939 0.061
D55-D59 Haemolytic anaemias
0.000 0.940 0.060
D51.2 Transcobalamin II deficiency
0.000 0.940 0.060
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.940 0.060
D61.1 Drug-induced aplastic anaemia
0.000 0.940 0.060
D83 Common variable immunodeficiency
0.000 0.941 0.059
D81 Combined immunodeficiencies
0.000 0.941 0.059
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.942 0.058
D84 Other immunodeficiencies
0.000 0.943 0.057
G25 Other extrapyramidal and movement disorders
0.000 0.943 0.057
D52.8 Other folate deficiency anaemias
0.000 0.943 0.057
D52.1 Drug-induced folate deficiency anaemia
0.000 0.943 0.057
D52.0 Dietary folate deficiency anaemia
0.000 0.943 0.057
K72.9 Hepatic failure, unspecified
0.000 0.943 0.057
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.944 0.056
G21 Secondary Parkinsonism
0.000 0.945 0.055
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.000 0.945 0.055
G22 Parkinsonism in diseases classified elsewhere
0.000 0.945 0.055
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.945 0.055
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.945 0.055
K72.0 Acute and subacute hepatic failure
0.000 0.945 0.055
G98 Other disorders of nervous system, not elsewhere classified
0.000 0.945 0.055
M46 Other inflammatory spondylopathies
0.000 0.945 0.054
K73.9 Chronic hepatitis, unspecified
0.000 0.946 0.054
D86.3 Sarcoidosis of skin
0.000 0.946 0.054
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.946 0.054
D86.0 Sarcoidosis of lung
0.000 0.947 0.053
K75.2 Nonspecific reactive hepatitis
0.000 0.947 0.052
K75.1 Phlebitis of portal vein
0.000 0.947 0.052
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.947 0.052
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.947 0.052
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.947 0.052
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.947 0.052
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.947 0.052
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.947 0.052
G93 Other disorders of brain
0.000 0.948 0.052
D53.9 Nutritional anaemia, unspecified
0.000 0.948 0.052
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.948 0.052
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.948 0.052
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.948 0.052
D82 Immunodeficiency associated with other major defects
0.000 0.948 0.052
G23 Other degenerative diseases of basal ganglia
0.000 0.948 0.052
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.949 0.051
D53.8 Other specified nutritional anaemias
0.000 0.949 0.051
D53.2 Scorbutic anaemia
0.000 0.949 0.051
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.949 0.051
D53.0 Protein deficiency anaemia
0.000 0.949 0.051
D89.1 Cryoglobulinaemia
0.000 0.949 0.051
G93.0 Cerebral cysts
0.000 0.950 0.050
K70.9 Alcoholic liver disease, unspecified
0.000 0.950 0.050
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.950 0.050
D60.8 Other acquired pure red cell aplasias
0.000 0.950 0.050
D60.1 Transient acquired pure red cell aplasia
0.000 0.950 0.050
D60.0 Chronic acquired pure red cell aplasia
0.000 0.950 0.050
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.950 0.049
D89.3 Immune reconstitution syndrome
0.000 0.950 0.049
E00-E07 Disorders of thyroid gland
0.000 0.950 0.049
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.951 0.049
K77 Liver disorders in diseases classified elsewhere
0.000 0.951 0.049
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.951 0.049
M49 Spondylopathies in diseases classified elsewhere
0.000 0.952 0.048
G25.0 Essential tremor
0.000 0.953 0.047
D84.9 Immunodeficiency, unspecified
0.000 0.953 0.047
D59 Acquired haemolytic anaemia
0.000 0.954 0.046
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.001 0.954 0.046
G25.3 Myoclonus
0.000 0.954 0.046
G93.5 Compression of brain
0.000 0.954 0.046
G94 Other disorders of brain in diseases classified elsewhere
0.000 0.954 0.046
L43.3 Subacute (active) lichen planus
0.001 0.954 0.045
L43.2 Lichenoid drug reaction
0.001 0.954 0.045
L43.1 Bullous lichen planus
0.001 0.954 0.045
L43.0 Hypertrophic lichen planus
0.001 0.954 0.045
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.955 0.045
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.955 0.045
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.955 0.045
D86.1 Sarcoidosis of lymph nodes
0.000 0.955 0.045
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.000 0.955 0.045
D62 Acute posthaemorrhagic anaemia
0.000 0.955 0.045
K70.3 Alcoholic cirrhosis of liver
0.000 0.955 0.045
G92 Toxic encephalopathy
0.000 0.956 0.044
K71 Toxic liver disease
0.000 0.956 0.043
D83.9 Common variable immunodeficiency, unspecified
0.000 0.956 0.043
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.957 0.043
D55 Anaemia due to enzyme disorders
0.000 0.957 0.043
G82.2 Paraplegia, unspecified
0.000 0.957 0.043
G25.2 Other specified forms of tremor
0.000 0.957 0.043
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.000 0.957 0.043
D83.8 Other common variable immunodeficiencies
0.000 0.957 0.043
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.957 0.043
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.957 0.043
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.957 0.043
G91 Hydrocephalus
0.000 0.958 0.042
K72.1 Chronic hepatic failure
0.000 0.958 0.042
D81.9 Combined immunodeficiency, unspecified
0.000 0.958 0.042
D81.8 Other combined immunodeficiencies
0.000 0.958 0.042
D81.7 Major histocompatibility complex class II deficiency
0.000 0.958 0.042
D81.6 Major histocompatibility complex class I deficiency
0.000 0.958 0.042
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.958 0.042
D81.4 Nezelof's syndrome
0.000 0.958 0.042
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.958 0.042
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.958 0.042
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.958 0.042
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.958 0.042
M46.0 Spinal enthesopathy
0.000 0.958 0.042
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.958 0.041
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.959 0.041
G25.6 Drug-induced tics and other tics of organic origin
0.000 0.959 0.041
G25.5 Other chorea
0.000 0.959 0.041
G25.4 Drug-induced chorea
0.000 0.959 0.041
G25.1 Drug-induced tremor
0.000 0.959 0.041
D58 Other hereditary haemolytic anaemias
0.000 0.959 0.041
G93.8 Other specified disorders of brain
0.000 0.959 0.041
D56 Thalassaemia
0.000 0.959 0.040
D57 Sickle-cell disorders
0.000 0.960 0.040
D84.1 Defects in the complement system
0.000 0.960 0.040
G21.9 Secondary Parkinsonism, unspecified
0.000 0.960 0.040
G21.8 Other secondary Parkinsonism
0.000 0.960 0.040
G21.4 Vascular parkinsonism
0.000 0.960 0.040
G21.3 Postencephalitic Parkinsonism
0.000 0.960 0.040
G21.2 Secondary Parkinsonism due to other external agents
0.000 0.960 0.040
G21.1 Other drug-induced secondary Parkinsonism
0.000 0.960 0.040
G21.0 Malignant neuroleptic syndrome
0.000 0.960 0.040
G93.1 Anoxic brain damage, not elsewhere classified
0.000 0.960 0.040
M46.2 Osteomyelitis of vertebra
0.000 0.961 0.039
M46.8 Other specified inflammatory spondylopathies
0.000 0.961 0.039
M46.5 Other infective spondylopathies
0.000 0.961 0.039
M46.1 Sacro-iliitis, not elsewhere classified
0.000 0.961 0.039
E07 Other disorders of thyroid
0.000 0.962 0.038
G25.9 Extrapyramidal and movement disorder, unspecified
0.000 0.962 0.038
G93.7 Reye's syndrome
0.000 0.962 0.038
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.962 0.037
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.962 0.037
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.962 0.037
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.962 0.037
D82.2 Immunodeficiency with short-limbed stature
0.000 0.962 0.037
D82.0 Wiskott-Aldrich syndrome
0.000 0.962 0.037
G23.9 Degenerative disease of basal ganglia, unspecified
0.000 0.963 0.037

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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