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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3873379
log Bayes Factor = 43.597
Chromosome 6   position 31,262,169  (GRCh37) Explore rs3873379 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.006 0.994
M45 Ankylosing spondylitis
0.000 0.035 0.965
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.059 0.941
L40.0 Psoriasis vulgaris
0.000 0.074 0.926
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.108 0.892
L40.8 Other psoriasis
0.000 0.204 0.796
L40.3 Pustulosis palmaris et plantaris
0.000 0.246 0.754
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.308 0.692
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.308 0.692
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.308 0.692
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.308 0.692
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.308 0.692
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.308 0.692
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.308 0.692
E03 Other hypothyroidism
0.000 0.336 0.664
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.392 0.608
M07.3 Other psoriatic arthropathies
0.000 0.414 0.586
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.422 0.578
E03.8 Other specified hypothyroidism
0.000 0.430 0.570
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.435 0.565
E03.5 Myxoedema coma
0.000 0.524 0.476
E03.4 Atrophy of thyroid (acquired)
0.000 0.524 0.476
E03.3 Postinfectious hypothyroidism
0.000 0.524 0.476
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.548 0.452
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.568 0.432
M07.38 Other psoriatic arthropathies (Other)
0.000 0.580 0.420
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.580 0.420
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.580 0.420
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.580 0.420
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.580 0.420
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.580 0.420
E03.1 Congenital hypothyroidism without goitre
0.000 0.583 0.417
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.587 0.413
G35 Multiple sclerosis
0.000 0.646 0.354
K90 Intestinal malabsorption
0.000 0.666 0.334
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.698 0.302
G30-G32 Other degenerative diseases of the nervous system
0.000 0.704 0.296
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.708 0.292
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.709 0.291
Chapter VI Diseases of the nervous system
0.000 0.726 0.274
G31.2 Degeneration of nervous system due to alcohol
0.000 0.727 0.273
G30 Alzheimer's disease
0.000 0.728 0.272
G31.8 Other specified degenerative diseases of nervous system
0.000 0.731 0.269
M07 Psoriatic and enteropathic arthropathies
0.001 0.734 0.265
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.000 0.744 0.256
L40-L45 Papulosquamous disorders
0.000 0.745 0.255
G30.9 Alzheimer's disease, unspecified
0.000 0.750 0.250
G31.0 Circumscribed brain atrophy
0.000 0.754 0.246
K90.3 Pancreatic steatorrhoea
0.000 0.761 0.239
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.761 0.239
K90.1 Tropical sprue
0.000 0.761 0.239
G62 Other polyneuropathies
0.000 0.761 0.239
D64.9 Anaemia, unspecified
0.000 0.765 0.235
G00-G09 Inflammatory diseases of the central nervous system
0.000 0.766 0.234
K90.8 Other intestinal malabsorption
0.000 0.767 0.233
D64 Other anaemias
0.000 0.769 0.231
G62.9 Polyneuropathy, unspecified
0.000 0.769 0.231
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.773 0.227
D50-D53 Nutritional anaemias
0.000 0.777 0.223
D60-D64 Aplastic and other anaemias
0.000 0.777 0.223
D50 Iron deficiency anaemia
0.000 0.778 0.222
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.783 0.217
D50.9 Iron deficiency anaemia, unspecified
0.000 0.783 0.217
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.784 0.216
G80-G83 Cerebral palsy and other paralytic syndromes
0.000 0.785 0.215
G70-G73 Diseases of myoneural junction and muscle
0.000 0.785 0.215
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.789 0.211
D61 Other aplastic anaemias
0.000 0.790 0.210
G30.1 Alzheimer's disease with late onset
0.000 0.791 0.209
D61.9 Aplastic anaemia, unspecified
0.000 0.795 0.205
K90.9 Intestinal malabsorption, unspecified
0.000 0.795 0.205
D64.8 Other specified anaemias
0.000 0.795 0.205
G61 Inflammatory polyneuropathy
0.000 0.796 0.204
D50.8 Other iron deficiency anaemias
0.000 0.798 0.202
G30.0 Alzheimer's disease with early onset
0.000 0.798 0.202
D80-D89 Certain disorders involving the immune mechanism
0.000 0.799 0.201
G83 Other paralytic syndromes
0.000 0.803 0.197
D51 Vitamin B12 deficiency anaemia
0.000 0.804 0.196
G60 Hereditary and idiopathic neuropathy
0.000 0.805 0.195
G36 Other acute disseminated demyelination
0.000 0.805 0.195
G06 Intracranial and intraspinal abscess and granuloma
0.000 0.806 0.194
G30.8 Other Alzheimer's disease
0.000 0.809 0.191
M07.6 Other enteropathic arthropathies
0.001 0.809 0.190
M07.5 Arthropathy in ulcerative colitis
0.001 0.809 0.190
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.809 0.190
M07.2 Psoriatic spondylitis
0.001 0.809 0.190
M07.1 Arthritis mutilans
0.001 0.809 0.190
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.809 0.190
G03 Meningitis due to other and unspecified causes
0.000 0.810 0.190
G62.1 Alcoholic polyneuropathy
0.000 0.811 0.189
G00 Bacterial meningitis, not elsewhere classified
0.000 0.813 0.187
G09 Sequelae of inflammatory diseases of central nervous system
0.000 0.815 0.185
G83.4 Cauda equina syndrome
0.000 0.815 0.185
G64 Other disorders of peripheral nervous system
0.000 0.816 0.184
L44 Other papulosquamous disorders
0.000 0.817 0.183
L41 Parapsoriasis
0.000 0.817 0.183
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.817 0.183
D52 Folate deficiency anaemia
0.000 0.817 0.183
D80 Immunodeficiency with predominantly antibody defects
0.000 0.822 0.178
G61.8 Other inflammatory polyneuropathies
0.000 0.822 0.178
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
0.000 0.823 0.177
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.823 0.177
L42 Pityriasis rosea
0.000 0.823 0.176
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.000 0.824 0.176
G71 Primary disorders of muscles
0.000 0.827 0.173
G62.2 Polyneuropathy due to other toxic agents
0.000 0.829 0.171
G01 Meningitis in bacterial diseases classified elsewhere
0.000 0.831 0.169
G83.9 Paralytic syndrome, unspecified
0.000 0.831 0.169
D53 Other nutritional anaemias
0.000 0.831 0.168
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.000 0.832 0.168
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.832 0.168
G63 Polyneuropathy in diseases classified elsewhere
0.000 0.834 0.166
D64.4 Congenital dyserythropoietic anaemia
0.000 0.834 0.166
D64.3 Other sideroblastic anaemias
0.000 0.834 0.166
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.834 0.166
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.834 0.166
D64.0 Hereditary sideroblastic anaemia
0.000 0.834 0.166
K75 Other inflammatory liver diseases
0.000 0.835 0.165
D86 Sarcoidosis
0.000 0.836 0.164
G60.0 Hereditary motor and sensory neuropathy
0.000 0.837 0.163
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere
0.000 0.837 0.163
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.838 0.162
K75.8 Other specified inflammatory liver diseases
0.000 0.839 0.161
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.840 0.160
G62.8 Other specified polyneuropathies
0.000 0.840 0.160
D50.1 Sideropenic dysphagia
0.000 0.840 0.160
G03.9 Meningitis, unspecified
0.000 0.841 0.159
K75.4 Autoimmune hepatitis
0.000 0.842 0.158
K70-K77 Diseases of liver
0.000 0.843 0.157
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.844 0.156
G06.0 Intracranial abscess and granuloma
0.000 0.844 0.156
G06.1 Intraspinal abscess and granuloma
0.000 0.844 0.156
K70 Alcoholic liver disease
0.000 0.845 0.155
K75.0 Abscess of liver
0.000 0.845 0.155
G72 Other myopathies
0.000 0.845 0.155
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.000 0.845 0.154
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.000 0.846 0.154
D52.9 Folate deficiency anaemia, unspecified
0.000 0.846 0.154
D80.1 Nonfamilial hypogammaglobulinaemia
0.000 0.847 0.153
G70 Myasthenia gravis and other myoneural disorders
0.000 0.848 0.152
D61.8 Other specified aplastic anaemias
0.000 0.849 0.151
D61.3 Idiopathic aplastic anaemia
0.000 0.849 0.151
D61.2 Aplastic anaemia due to other external agents
0.000 0.849 0.151
G00.1 Pneumococcal meningitis
0.000 0.849 0.150
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.850 0.150
G04 Encephalitis, myelitis and encephalomyelitis
0.000 0.851 0.149
G81 Hemiplegia
0.000 0.851 0.149
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.000 0.851 0.148
G61.1 Serum neuropathy
0.000 0.853 0.147
D86.0 Sarcoidosis of lung
0.000 0.854 0.146
D83 Common variable immunodeficiency
0.000 0.854 0.146
G83.1 Monoplegia of lower limb
0.000 0.855 0.145
K72 Hepatic failure, not elsewhere classified
0.000 0.856 0.144
D81 Combined immunodeficiencies
0.000 0.856 0.144
D55-D59 Haemolytic anaemias
0.000 0.856 0.144
D86.3 Sarcoidosis of skin
0.000 0.856 0.144
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.000 0.856 0.144
K73 Chronic hepatitis, not elsewhere classified
0.000 0.857 0.143
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.000 0.857 0.143
K70.1 Alcoholic hepatitis
0.000 0.857 0.143
G61.0 Guillain-Barre syndrome
0.000 0.858 0.142
G83.5 Locked-in syndrome
0.000 0.858 0.141
G83.3 Monoplegia, unspecified
0.000 0.858 0.141
G83.0 Diplegia of upper limbs
0.000 0.858 0.141
D61.0 Constitutional aplastic anaemia
0.000 0.859 0.141
D51.2 Transcobalamin II deficiency
0.000 0.859 0.141
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.859 0.141
D84 Other immunodeficiencies
0.000 0.859 0.141
G60.3 Idiopathic progressive neuropathy
0.000 0.860 0.140
G60.2 Neuropathy in association with hereditary ataxia
0.000 0.860 0.140
G60.1 Refsum's disease
0.000 0.860 0.140
G36.9 Acute disseminated demyelination, unspecified
0.000 0.860 0.140
G36.8 Other specified acute disseminated demyelination
0.000 0.860 0.140
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.860 0.140
K70.4 Alcoholic hepatic failure
0.000 0.862 0.138
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.863 0.136
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.863 0.136
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.863 0.136
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.863 0.136
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.863 0.136
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.863 0.136
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.863 0.136
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.863 0.136
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.863 0.136
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.863 0.136
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.863 0.136
M07.18 Arthritis mutilans (Other)
0.001 0.863 0.136
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.863 0.136
M07.16 Arthritis mutilans (Lower leg)
0.001 0.863 0.136
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.863 0.136
M07.14 Arthritis mutilans (Hand)
0.001 0.863 0.136
M07.13 Arthritis mutilans (Forearm)
0.001 0.863 0.136
M07.12 Arthritis mutilans (Upper arm)
0.001 0.863 0.136
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.863 0.136
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.863 0.136
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.863 0.136
M07.28 Psoriatic spondylitis (Other)
0.001 0.863 0.136
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.863 0.136
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.863 0.136
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.863 0.136
M07.24 Psoriatic spondylitis (Hand)
0.001 0.863 0.136
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.863 0.136
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.863 0.136
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.863 0.136
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.863 0.136
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.863 0.136
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.863 0.136
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.863 0.136
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.863 0.136
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.863 0.136
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.863 0.136
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.863 0.136
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.863 0.136
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.863 0.136
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.863 0.136
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.863 0.136
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.863 0.136
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.863 0.136
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.863 0.136
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.863 0.136
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.863 0.136
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.863 0.136
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.863 0.136
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.863 0.136
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.863 0.136
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.863 0.136
M07.68 Other enteropathic arthropathies (Other)
0.001 0.863 0.136
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.863 0.136
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.863 0.136
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.863 0.136
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.863 0.136
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.863 0.136
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.863 0.136
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.863 0.136
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.863 0.136
G00.9 Bacterial meningitis, unspecified
0.000 0.863 0.137
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.000 0.863 0.137
D61.1 Drug-induced aplastic anaemia
0.000 0.863 0.137
G03.8 Meningitis due to other specified causes
0.000 0.863 0.136
G03.2 Benign recurrent meningitis [Mollaret]
0.000 0.863 0.136
G03.1 Chronic meningitis
0.000 0.863 0.136
G03.0 Nonpyogenic meningitis
0.000 0.863 0.136
K70.0 Alcoholic fatty liver
0.000 0.864 0.136
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.000 0.864 0.136
G06.2 Extradural and subdural abscess, unspecified
0.000 0.864 0.135
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.865 0.135
G00.8 Other bacterial meningitis
0.000 0.866 0.134
G00.3 Staphylococcal meningitis
0.000 0.866 0.134
G00.2 Streptococcal meningitis
0.000 0.866 0.134
G00.0 Haemophilus meningitis
0.000 0.866 0.134
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere
0.000 0.866 0.134
L41.9 Parapsoriasis, unspecified
0.000 0.869 0.131
L41.8 Other parapsoriasis
0.000 0.869 0.131
L41.5 Retiform parapsoriasis
0.000 0.869 0.131
L41.4 Large plaque parapsoriasis
0.000 0.869 0.131
L41.3 Small plaque parapsoriasis
0.000 0.869 0.131
L41.2 Lymphomatoid papulosis
0.000 0.869 0.131
L41.1 Pityriasis lichenoides chronica
0.000 0.869 0.131
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.869 0.131
L44.9 Papulosquamous disorder, unspecified
0.000 0.869 0.131
L44.8 Other specified papulosquamous disorders
0.000 0.869 0.131
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.869 0.131
L44.3 Lichen ruber moniliformis
0.000 0.869 0.131
L44.2 Lichen striatus
0.000 0.869 0.131
L44.1 Lichen nitidus
0.000 0.869 0.131
L44.0 Pityriasis rubra pilaris
0.000 0.869 0.131
D52.8 Other folate deficiency anaemias
0.000 0.869 0.131
D52.1 Drug-induced folate deficiency anaemia
0.000 0.869 0.131
D52.0 Dietary folate deficiency anaemia
0.000 0.869 0.131
G82 Paraplegia and tetraplegia
0.000 0.869 0.131
G61.9 Inflammatory polyneuropathy, unspecified
0.000 0.869 0.130
D53.9 Nutritional anaemia, unspecified
0.000 0.871 0.129
D80.8 Other immunodeficiencies with predominantly antibody defects
0.000 0.872 0.128
D80.7 Transient hypogammaglobulinaemia of infancy
0.000 0.872 0.128
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.000 0.872 0.128
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.000 0.872 0.128
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.000 0.872 0.128
D80.0 Hereditary hypogammaglobulinaemia
0.000 0.872 0.128
K72.9 Hepatic failure, unspecified
0.000 0.872 0.128
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.872 0.128
D82 Immunodeficiency associated with other major defects
0.000 0.873 0.127
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.873 0.127
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.873 0.127
G62.0 Drug-induced polyneuropathy
0.000 0.873 0.127
G83.8 Other specified paralytic syndromes
0.000 0.874 0.126
D86.1 Sarcoidosis of lymph nodes
0.000 0.874 0.126
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere
0.000 0.874 0.126
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere
0.000 0.874 0.126
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere
0.000 0.874 0.126
G60.8 Other hereditary and idiopathic neuropathies
0.000 0.874 0.126
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.874 0.125
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.000 0.875 0.125
G36.0 Neuromyelitis optica [Devic]
0.000 0.875 0.125
G71.9 Primary disorder of muscle, unspecified
0.000 0.876 0.124
G71.8 Other primary disorders of muscles
0.000 0.876 0.124
G71.2 Congenital myopathies
0.000 0.876 0.124
G80 Infantile cerebral palsy
0.000 0.876 0.124
K72.0 Acute and subacute hepatic failure
0.000 0.876 0.124
G71.1 Myotonic disorders
0.000 0.877 0.123
D89.1 Cryoglobulinaemia
0.000 0.877 0.123
K73.9 Chronic hepatitis, unspecified
0.000 0.877 0.123
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.877 0.123
D62 Acute posthaemorrhagic anaemia
0.000 0.878 0.122
G12 Spinal muscular atrophy and related syndromes
0.000 0.878 0.122
G81.1 Spastic hemiplegia
0.000 0.878 0.122
D53.8 Other specified nutritional anaemias
0.000 0.879 0.121
D53.2 Scorbutic anaemia
0.000 0.879 0.121
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.879 0.121
D53.0 Protein deficiency anaemia
0.000 0.879 0.121
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.879 0.121
D89.3 Immune reconstitution syndrome
0.000 0.879 0.121
G63.8 Polyneuropathy in other diseases classified elsewhere
0.000 0.881 0.119
G63.6 Polyneuropathy in other musculoskeletal disorders
0.000 0.881 0.119
G63.5 Polyneuropathy in systemic connective tissue disorders
0.000 0.881 0.119
G63.4 Polyneuropathy in nutritional deficiency
0.000 0.881 0.119
G63.3 Polyneuropathy in other endocrine and metabolic diseases
0.000 0.881 0.119
G63.1 Polyneuropathy in neoplastic disease
0.000 0.881 0.119
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere
0.000 0.881 0.119
K75.2 Nonspecific reactive hepatitis
0.000 0.881 0.119
K75.1 Phlebitis of portal vein
0.000 0.881 0.119
K70.9 Alcoholic liver disease, unspecified
0.000 0.882 0.118
G37 Other demyelinating diseases of central nervous system
0.000 0.882 0.118
G72.9 Myopathy, unspecified
0.000 0.883 0.117
G70.0 Myasthenia gravis
0.000 0.884 0.116
D60.9 Acquired pure red cell aplasia, unspecified
0.000 0.885 0.115
D60.8 Other acquired pure red cell aplasias
0.000 0.885 0.115
D60.1 Transient acquired pure red cell aplasia
0.000 0.885 0.115
D60.0 Chronic acquired pure red cell aplasia
0.000 0.885 0.115
D84.9 Immunodeficiency, unspecified
0.000 0.886 0.114
K77 Liver disorders in diseases classified elsewhere
0.000 0.887 0.113
G72.8 Other specified myopathies
0.000 0.888 0.112
G72.0 Drug-induced myopathy
0.000 0.888 0.112
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.000 0.888 0.112
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.888 0.112
G72.3 Periodic paralysis
0.000 0.889 0.111
G72.2 Myopathy due to other toxic agents
0.000 0.889 0.111
G72.1 Alcoholic myopathy
0.000 0.889 0.111
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere
0.000 0.889 0.111
D59 Acquired haemolytic anaemia
0.000 0.889 0.111
G71.0 Muscular dystrophy
0.000 0.889 0.111
G73.7 Myopathy other diseases classified elsewhere
0.000 0.889 0.111
G73.6 Myopathy in metabolic diseases
0.000 0.889 0.111
G73.5 Myopathy in endocrine diseases
0.000 0.889 0.111
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere
0.000 0.889 0.111
G73.3 Myasthenic syndromes in other diseases classified elsewhere
0.000 0.889 0.111
G73.2 Other myasthenic syndromes in neoplastic disease
0.000 0.889 0.111
G73.1 Eaton-Lambert syndrome
0.000 0.889 0.111
G73.0 Myasthenic syndromes in endocrine diseases
0.000 0.889 0.111
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.000 0.889 0.110
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.889 0.110
G70.8 Other specified myoneural disorders
0.000 0.891 0.109
G70.2 Congenital and developmental myasthenia
0.000 0.891 0.109
G70.1 Toxic myoneural disorders
0.000 0.891 0.109
E00-E07 Disorders of thyroid gland
0.000 0.892 0.108
G82.1 Spastic paraplegia
0.000 0.892 0.108
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified
0.000 0.893 0.107
G04.1 Tropical spastic paraplegia
0.000 0.893 0.107
G81.0 Flaccid hemiplegia
0.000 0.893 0.107
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere
0.000 0.893 0.107
G02.1 Meningitis in mycoses
0.000 0.893 0.107
D83.9 Common variable immunodeficiency, unspecified
0.000 0.894 0.106
D83.8 Other common variable immunodeficiencies
0.000 0.895 0.105
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.000 0.895 0.105
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.000 0.895 0.105
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.000 0.895 0.105
N39.3 Stress incontinence
0.104 0.896 0.000
D81.9 Combined immunodeficiency, unspecified
0.000 0.896 0.103
D81.8 Other combined immunodeficiencies
0.000 0.896 0.103
D81.7 Major histocompatibility complex class II deficiency
0.000 0.896 0.103
D81.6 Major histocompatibility complex class I deficiency
0.000 0.896 0.103
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.000 0.896 0.103
D81.4 Nezelof's syndrome
0.000 0.896 0.103
D81.3 Adenosine deaminase [ADA] deficiency
0.000 0.896 0.103
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.000 0.896 0.103
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.000 0.896 0.103
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.000 0.896 0.103
D55 Anaemia due to enzyme disorders
0.000 0.896 0.103
G72.4 Inflammatory myopathy, not elsewhere classified
0.000 0.897 0.103
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.897 0.103
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.897 0.103
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.000 0.897 0.103
M45-M49 Spondylopathies
0.000 0.897 0.103
G83.2 Monoplegia of upper limb
0.000 0.897 0.102
G11 Hereditary ataxia
0.000 0.898 0.102
G63.2 Diabetic polyneuropathy
0.000 0.898 0.102
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.000 0.899 0.101
K71 Toxic liver disease
0.000 0.900 0.100
K70.3 Alcoholic cirrhosis of liver
0.000 0.900 0.100
G12.2 Motor neuron disease
0.000 0.901 0.099
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.901 0.098
G70.9 Myoneural disorder, unspecified
0.000 0.902 0.098
D84.1 Defects in the complement system
0.000 0.902 0.098
D58 Other hereditary haemolytic anaemias
0.000 0.902 0.098
D56 Thalassaemia
0.000 0.903 0.097
G14 Postpolio syndrome
0.000 0.903 0.096
D86.9 Sarcoidosis, unspecified
0.000 0.903 0.097
D57 Sickle-cell disorders
0.000 0.903 0.096
K72.1 Chronic hepatic failure
0.000 0.904 0.096
G80.2 Infantile hemiplegia
0.000 0.906 0.094
G82.3 Flaccid tetraplegia
0.000 0.906 0.094
G82.0 Flaccid paraplegia
0.000 0.906 0.094
G80.0 Spastic cerebral palsy
0.000 0.908 0.092
D82.9 Immunodeficiency associated with major defect, unspecified
0.000 0.908 0.091
D82.8 Immunodeficiency associated with other specified major defects
0.000 0.908 0.091
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.000 0.908 0.091
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.000 0.908 0.091
D82.2 Immunodeficiency with short-limbed stature
0.000 0.908 0.091
D82.0 Wiskott-Aldrich syndrome
0.000 0.908 0.091
G82.4 Spastic tetraplegia
0.000 0.909 0.091
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.910 0.090
G82.5 Tetraplegia, unspecified
0.000 0.910 0.090
G80.8 Other infantile cerebral palsy
0.000 0.911 0.089
G80.4 Ataxic cerebral palsy
0.000 0.911 0.089
G80.3 Dyskinetic cerebral palsy
0.000 0.911 0.089
G12.9 Spinal muscular atrophy, unspecified
0.000 0.912 0.088
G12.8 Other spinal muscular atrophies and related syndromes
0.000 0.912 0.088
G12.1 Other inherited spinal muscular atrophy
0.000 0.912 0.088
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]
0.000 0.912 0.088
D59.1 Other autoimmune haemolytic anaemias
0.000 0.913 0.087
G04.0 Acute disseminated encephalitis
0.000 0.913 0.087
G02.0 Meningitis in viral diseases classified elsewhere
0.000 0.913 0.087
E07 Other disorders of thyroid
0.000 0.913 0.087
G37.5 Concentric sclerosis [Balo]
0.000 0.915 0.084
G37.4 Subacute necrotising myelitis
0.000 0.915 0.084
G37.2 Central pontine myelinolysis
0.000 0.915 0.084
G37.1 Central demyelination of corpus callosum
0.000 0.915 0.084
G37.0 Diffuse sclerosis
0.000 0.915 0.084
G10 Huntington's disease
0.000 0.917 0.083
K90-K93 Other diseases of the digestive system
0.000 0.918 0.082
D84.8 Other specified immunodeficiencies
0.000 0.919 0.081
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.919 0.081
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.919 0.081
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
0.000 0.920 0.080
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema
0.000 0.920 0.080
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
0.000 0.920 0.080
G13.0 Paraneoplastic neuromyopathy and neuropathy
0.000 0.920 0.080
D59.8 Other acquired haemolytic anaemias
0.000 0.920 0.080
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.920 0.080
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.920 0.080
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.920 0.080
D59.3 Haemolytic-uraemic syndrome
0.000 0.920 0.080
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.920 0.080
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.920 0.080
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.920 0.079
E07.8 Other specified disorders of thyroid
0.000 0.921 0.079
G80.1 Spastic diplegia
0.000 0.921 0.079
G11.4 Hereditary spastic paraplegia
0.000 0.922 0.078
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.922 0.078
E00 Congenital iodine-deficiency syndrome
0.000 0.922 0.078
D82.1 Di George's syndrome
0.000 0.925 0.075
G20-G26 Extrapyramidal and movement disorders
0.000 0.925 0.075
D63 Anaemia in chronic diseases classified elsewhere
0.000 0.925 0.075
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.925 0.075
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.926 0.074
D55.8 Other anaemias due to enzyme disorders
0.000 0.926 0.074
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.926 0.074
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.926 0.074
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.926 0.074
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.926 0.074
G81.9 Hemiplegia, unspecified
0.000 0.926 0.074
L43 Lichen planus
0.001 0.926 0.073
G11.8 Other hereditary ataxias
0.000 0.927 0.073
G11.3 Cerebellar ataxia with defective DNA repair
0.000 0.927 0.073
G11.2 Late-onset cerebellar ataxia
0.000 0.927 0.073
G11.0 Congenital nonprogressive ataxia
0.000 0.927 0.073
K71.9 Toxic liver disease, unspecified
0.000 0.928 0.072
K71.8 Toxic liver disease with other disorders of liver
0.000 0.928 0.072
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.928 0.072
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.928 0.072
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.928 0.072
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.928 0.072
K71.2 Toxic liver disease with acute hepatitis
0.000 0.928 0.072
K71.0 Toxic liver disease with cholestasis
0.000 0.928 0.072
D58.0 Hereditary spherocytosis
0.000 0.928 0.072
M46 Other inflammatory spondylopathies
0.000 0.928 0.072
D56.1 Beta thalassaemia
0.000 0.929 0.071
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.930 0.070
D58.1 Hereditary elliptocytosis
0.000 0.930 0.070
D56.9 Thalassaemia, unspecified
0.000 0.930 0.069
D56.8 Other thalassaemias
0.000 0.930 0.069
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.930 0.069
D56.2 Delta-beta thalassaemia
0.000 0.930 0.069
D56.0 Alpha thalassaemia
0.000 0.930 0.069
D57.8 Other sickle-cell disorders
0.000 0.930 0.069
D57.3 Sickle-cell trait
0.000 0.930 0.069
D57.2 Double heterozygous sickling disorders
0.000 0.930 0.069
D57.0 Sickle-cell anaemia with crisis
0.000 0.930 0.069
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.931 0.069
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.931 0.069
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.931 0.068
G11.1 Early-onset cerebellar ataxia
0.000 0.933 0.067
K75.9 Inflammatory liver disease, unspecified
0.000 0.935 0.065

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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