TreeWAS – Variant ID: rs3873386

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	0.000	0.000	1.000
M45.X9 Ankylosing spondylitis (Site unspecified)	1.000	0.000	0.000
R31 Unspecified haematuria	1.000	0.000	0.000
G35 Multiple sclerosis	0.000	0.004	0.996
M45 Ankylosing spondylitis	0.992	0.008	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.986	0.014	0.000
E03 Other hypothyroidism	0.000	0.050	0.950
L40 Psoriasis	0.000	0.061	0.939
E03.8 Other specified hypothyroidism	0.000	0.123	0.877
L40.5 Arthropathic psoriasis	0.000	0.131	0.869
L40.0 Psoriasis vulgaris	0.000	0.134	0.866
M45.X2 Ankylosing spondylitis (Cervical region)	0.818	0.182	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.197	0.803
L40.1 Generalised pustular psoriasis	0.000	0.231	0.769
E00-E07 Disorders of thyroid gland	0.000	0.254	0.746
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.270	0.730
M45.X6 Ankylosing spondylitis (Lumbar region)	0.721	0.278	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.711	0.289	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.711	0.289	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.711	0.289	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.711	0.289	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.711	0.289	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.711	0.289	0.000
K75 Other inflammatory liver diseases	0.000	0.291	0.709
K75.4 Autoimmune hepatitis	0.000	0.295	0.705
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.298	0.702
K90 Intestinal malabsorption	0.000	0.300	0.700
K75.8 Other specified inflammatory liver diseases	0.000	0.301	0.699
E05.9 Thyrotoxicosis, unspecified	0.000	0.310	0.690
E03.5 Myxoedema coma	0.000	0.319	0.681
E03.4 Atrophy of thyroid (acquired)	0.000	0.319	0.681
E03.3 Postinfectious hypothyroidism	0.000	0.319	0.681
K70-K77 Diseases of liver	0.000	0.324	0.676
L40.2 Acrodermatitis continua	0.000	0.327	0.673
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.335	0.665
L40.3 Pustulosis palmaris et plantaris	0.000	0.343	0.657
L40.8 Other psoriasis	0.000	0.344	0.656
E03.1 Congenital hypothyroidism without goitre	0.000	0.347	0.653
K73 Chronic hepatitis, not elsewhere classified	0.000	0.357	0.643
K70 Alcoholic liver disease	0.000	0.362	0.638
K75.0 Abscess of liver	0.000	0.386	0.614
M05.9 Seropositive rheumatoid arthritis, unspecified	0.594	0.406	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.410	0.590
K70.1 Alcoholic hepatitis	0.000	0.416	0.584
M05 Seropositive rheumatoid arthritis	0.580	0.420	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.420	0.580
K70.4 Alcoholic hepatic failure	0.000	0.426	0.574
M06 Other rheumatoid arthritis	0.571	0.429	0.000
M05-M14 Inflammatory polyarthropathies	0.570	0.430	0.000
E07 Other disorders of thyroid	0.000	0.431	0.569
K72 Hepatic failure, not elsewhere classified	0.000	0.432	0.568
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.568	0.432	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.435	0.565
M06.9 Rheumatoid arthritis, unspecified	0.556	0.444	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.549	0.451	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.548	0.452	0.000
D64.9 Anaemia, unspecified	0.000	0.453	0.547
D64 Other anaemias	0.000	0.457	0.543
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.458	0.542
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.465	0.535
E00 Congenital iodine-deficiency syndrome	0.000	0.465	0.535
D60-D64 Aplastic and other anaemias	0.000	0.469	0.531
K74 Fibrosis and cirrhosis of liver	0.000	0.469	0.531
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.473	0.527
L40.4 Guttate psoriasis	0.000	0.473	0.527
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.527	0.473	0.000
K70.0 Alcoholic fatty liver	0.000	0.475	0.525
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.476	0.524
E05.5 Thyroid crisis or storm	0.000	0.477	0.523
E05.4 Thyrotoxicosis factitia	0.000	0.477	0.523
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.477	0.523
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.478	0.522
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.481	0.519
E07.8 Other specified disorders of thyroid	0.000	0.484	0.516
D61 Other aplastic anaemias	0.000	0.484	0.516
K74.0 Hepatic fibrosis	0.000	0.489	0.511
D61.9 Aplastic anaemia, unspecified	0.000	0.491	0.509
K90.8 Other intestinal malabsorption	0.000	0.491	0.508
K75.2 Nonspecific reactive hepatitis	0.000	0.492	0.508
K75.1 Phlebitis of portal vein	0.000	0.492	0.508
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.496	0.504
K72.0 Acute and subacute hepatic failure	0.000	0.497	0.503
M45-M49 Spondylopathies	0.502	0.498	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.498	0.502
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.498	0.502
K90.1 Tropical sprue	0.000	0.498	0.502
M06.3 Rheumatoid nodule	0.500	0.500	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.500	0.500
D50-D53 Nutritional anaemias	0.000	0.503	0.497
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.489	0.511	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.512	0.488
D64.8 Other specified anaemias	0.000	0.512	0.488
K77 Liver disorders in diseases classified elsewhere	0.000	0.515	0.485
M06.4 Inflammatory polyarthropathy	0.480	0.520	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.521	0.479
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.476	0.524	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.473	0.526	0.000
M06.0 Seronegative rheumatoid arthritis	0.473	0.527	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.472	0.528	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.533	0.467
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.539	0.461
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.539	0.461
M08 Juvenile arthritis	0.455	0.545	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.446	0.554	0.000
M14 Arthropathies in other diseases classified elsewhere	0.445	0.555	0.000
M06.34 Rheumatoid nodule (Hand)	0.443	0.557	0.000
M05.1 Rheumatoid lung disease	0.442	0.558	0.000
E06 Thyroiditis	0.000	0.560	0.440
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.440	0.560	0.000
M12 Other specific arthropathies	0.434	0.566	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.434	0.566	0.000
K72.9 Hepatic failure, unspecified	0.000	0.571	0.428
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.426	0.574	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.423	0.577	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.423	0.577	0.000
M05.2 Rheumatoid vasculitis	0.422	0.578	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.418	0.582	0.000
K71 Toxic liver disease	0.000	0.583	0.417
D52 Folate deficiency anaemia	0.000	0.583	0.416
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.416	0.584	0.000
M05.0 Felty's syndrome	0.416	0.584	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.584	0.416
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.411	0.589	0.000
M06.8 Other specified rheumatoid arthritis	0.410	0.590	0.000
M06.2 Rheumatoid bursitis	0.409	0.590	0.000
M06.1 Adult-onset Still's disease	0.409	0.590	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.409	0.591	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.409	0.591	0.000
E07.1 Dyshormogenetic goitre	0.000	0.592	0.408
E07.0 Hypersecretion of calcitonin	0.000	0.592	0.408
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.593	0.407
M49 Spondylopathies in diseases classified elsewhere	0.406	0.593	0.000
D50 Iron deficiency anaemia	0.000	0.596	0.404
L40-L45 Papulosquamous disorders	0.000	0.597	0.403
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.403	0.597	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.402	0.598	0.000
M11 Other crystal arthropathies	0.402	0.598	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.399	0.601	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.601	0.399
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.396	0.604	0.000
D64.4 Congenital dyserythropoietic anaemia	0.000	0.611	0.389
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.611	0.389
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.611	0.389
D64.0 Hereditary sideroblastic anaemia	0.000	0.611	0.389
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.616	0.384
M05.8 Other seropositive rheumatoid arthritis	0.384	0.616	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.616	0.383
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.616	0.383
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.616	0.383
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.616	0.383
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.616	0.383
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.616	0.383
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.616	0.383
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.616	0.383
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.619	0.381
D64.3 Other sideroblastic anaemias	0.000	0.619	0.381
K74.4 Secondary biliary cirrhosis	0.000	0.619	0.380
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.619	0.380
M06.32 Rheumatoid nodule (Upper arm)	0.380	0.620	0.000
E06.3 Autoimmune thyroiditis	0.000	0.622	0.378
M06.30 Rheumatoid nodule (Multiple sites)	0.378	0.622	0.000
D53 Other nutritional anaemias	0.000	0.627	0.373
M08.0 Juvenile rheumatoid arthritis	0.372	0.628	0.000
D69 Purpura and other haemorrhagic conditions	0.000	0.629	0.371
M06.33 Rheumatoid nodule (Forearm)	0.371	0.629	0.000
D50.9 Iron deficiency anaemia, unspecified	0.000	0.629	0.371
D61.8 Other specified aplastic anaemias	0.000	0.630	0.370
D61.3 Idiopathic aplastic anaemia	0.000	0.630	0.370
D61.2 Aplastic anaemia due to other external agents	0.000	0.630	0.370
D55-D59 Haemolytic anaemias	0.000	0.631	0.369
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.369	0.631	0.000
D69.6 Thrombocytopenia, unspecified	0.000	0.636	0.364
G36 Other acute disseminated demyelination	0.000	0.637	0.363
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.637	0.363
D52.9 Folate deficiency anaemia, unspecified	0.000	0.641	0.359
M06.39 Rheumatoid nodule (Site unspecified)	0.359	0.641	0.000
M06.38 Rheumatoid nodule (Other)	0.359	0.641	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.359	0.641	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.359	0.641	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.359	0.641	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.358	0.642	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.642	0.358
G37 Other demyelinating diseases of central nervous system	0.000	0.642	0.358
M06.04 Seronegative rheumatoid arthritis (Hand)	0.355	0.645	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.355	0.645	0.000
D61.1 Drug-induced aplastic anaemia	0.000	0.645	0.354
K74.1 Hepatic sclerosis	0.000	0.650	0.350
K72.1 Chronic hepatic failure	0.000	0.650	0.350
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.349	0.651	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.652	0.347
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.652	0.347
D80 Immunodeficiency with predominantly antibody defects	0.000	0.652	0.348
M06.48 Inflammatory polyarthropathy (Other)	0.344	0.655	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.344	0.655	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.344	0.655	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.344	0.655	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.344	0.655	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.344	0.655	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.344	0.655	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.344	0.655	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.656	0.344
D51.2 Transcobalamin II deficiency	0.000	0.656	0.344
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.656	0.344
M05.19 Rheumatoid lung disease (Site unspecified)	0.343	0.657	0.000
E05.8 Other thyrotoxicosis	0.001	0.657	0.342
M13 Other arthritis	0.341	0.659	0.000
D61.0 Constitutional aplastic anaemia	0.000	0.659	0.341
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.340	0.660	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.339	0.660	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.339	0.660	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.339	0.660	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.339	0.661	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.661	0.339
M49.5 Collapsed vertebra in diseases classified elsewhere	0.338	0.662	0.000
M12.2 Villonodular synovitis (pigmented)	0.337	0.663	0.000
M48 Other spondylopathies	0.336	0.664	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.669	0.331
K90-K93 Other diseases of the digestive system	0.000	0.669	0.331
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.671	0.328
K74.5 Biliary cirrhosis, unspecified	0.000	0.673	0.326
M08.9 Juvenile arthritis, unspecified	0.326	0.674	0.000
M08.8 Other juvenile arthritis	0.326	0.674	0.000
M08.4 Pauciarticular juvenile arthritis	0.326	0.674	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.326	0.674	0.000
M08.2 Juvenile arthritis with systemic onset	0.326	0.674	0.000
M08.1 Juvenile ankylosing spondylitis	0.326	0.674	0.000
D69.4 Other primary thrombocytopenia	0.000	0.677	0.323
M14.6 Neuropathic arthropathy	0.323	0.677	0.000
M14.2 Diabetic arthropathy	0.321	0.679	0.000
M14.4 Arthropathy in amyloidosis	0.319	0.681	0.000
M14.3 Lipoid dermatoarthritis	0.319	0.681	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.319	0.681	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.319	0.681	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.319	0.681	0.000
M05.18 Rheumatoid lung disease (Other)	0.317	0.683	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.317	0.683	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.317	0.683	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.317	0.683	0.000
M05.14 Rheumatoid lung disease (Hand)	0.317	0.683	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.317	0.683	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.317	0.683	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.317	0.683	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.317	0.683	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.683	0.317
M05.20 Rheumatoid vasculitis (Multiple sites)	0.316	0.684	0.000
E06.4 Drug-induced thyroiditis	0.000	0.684	0.315
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.684	0.315
E06.0 Acute thyroiditis	0.000	0.684	0.315
M06.37 Rheumatoid nodule (Ankle and foot)	0.314	0.686	0.000
D84 Other immunodeficiencies	0.000	0.687	0.313
M12.3 Palindromic rheumatism	0.312	0.688	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.311	0.688	0.000
M12.5 Traumatic arthropathy	0.311	0.688	0.000
M12.4 Intermittent hydrarthrosis	0.311	0.688	0.000
M12.1 Kaschin-Beck disease	0.311	0.688	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.311	0.688	0.000
Chapter VI Diseases of the nervous system	0.000	0.689	0.311
M11.9 Crystal arthropathy, unspecified	0.310	0.690	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.310	0.690	0.000
M07 Psoriatic and enteropathic arthropathies	0.308	0.691	0.001
D59 Acquired haemolytic anaemia	0.000	0.692	0.308
Chapter XI Diseases of the digestive system	0.000	0.692	0.308
K71.0 Toxic liver disease with cholestasis	0.000	0.692	0.307
D83 Common variable immunodeficiency	0.000	0.694	0.306
M46 Other inflammatory spondylopathies	0.304	0.696	0.000
M05.28 Rheumatoid vasculitis (Other)	0.303	0.697	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.303	0.697	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.303	0.697	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.303	0.697	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.303	0.697	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.303	0.697	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.303	0.697	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.303	0.697	0.000
M48.9 Spondylopathy, unspecified	0.302	0.698	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.302	0.698	0.000
M00-M03 Infectious arthropathies	0.301	0.699	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.300	0.700	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.700	0.300
E06.5 Other chronic thyroiditis	0.000	0.700	0.299
K71.9 Toxic liver disease, unspecified	0.000	0.701	0.299
K71.8 Toxic liver disease with other disorders of liver	0.000	0.701	0.299
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.701	0.299
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.701	0.299
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.701	0.299
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.701	0.299
K71.2 Toxic liver disease with acute hepatitis	0.000	0.701	0.299
D52.8 Other folate deficiency anaemias	0.000	0.701	0.299
D52.1 Drug-induced folate deficiency anaemia	0.000	0.701	0.299
D52.0 Dietary folate deficiency anaemia	0.000	0.701	0.299
M05.09 Felty's syndrome (Site unspecified)	0.298	0.701	0.000
M05.08 Felty's syndrome (Other)	0.298	0.701	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.298	0.701	0.000
M05.06 Felty's syndrome (Lower leg)	0.298	0.701	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.298	0.701	0.000
M05.04 Felty's syndrome (Hand)	0.298	0.701	0.000
M05.03 Felty's syndrome (Forearm)	0.298	0.701	0.000
M05.02 Felty's syndrome (Upper arm)	0.298	0.701	0.000
M05.01 Felty's syndrome (Shoulder region)	0.298	0.701	0.000
M05.00 Felty's syndrome (Multiple sites)	0.298	0.701	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.298	0.701	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.298	0.701	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.298	0.701	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.298	0.701	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.298	0.701	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.298	0.701	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.298	0.701	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.298	0.701	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.298	0.701	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.298	0.701	0.000
D81 Combined immunodeficiencies	0.000	0.702	0.298
M91-M94 Chondropathies	0.298	0.702	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.705	0.295
M05.29 Rheumatoid vasculitis (Site unspecified)	0.295	0.705	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.705	0.295
M06.88 Other specified rheumatoid arthritis (Other)	0.294	0.706	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.294	0.706	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.294	0.706	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.294	0.706	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.294	0.706	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.294	0.706	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.294	0.706	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.294	0.706	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.294	0.706	0.000
M06.18 Adult-onset Still's disease (Other)	0.294	0.706	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.294	0.706	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.294	0.706	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.294	0.706	0.000
M06.14 Adult-onset Still's disease (Hand)	0.294	0.706	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.294	0.706	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.294	0.706	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.294	0.706	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.294	0.706	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.294	0.706	0.000
M06.28 Rheumatoid bursitis (Other)	0.294	0.706	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.294	0.706	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.294	0.706	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.294	0.706	0.000
M06.24 Rheumatoid bursitis (Hand)	0.294	0.706	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.294	0.706	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.294	0.706	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.294	0.706	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.294	0.706	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.293	0.707	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.293	0.707	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.293	0.707	0.000
M09.0 Juvenile arthritis in psoriasis	0.293	0.707	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.000	0.707	0.293
M49.8 Spondylopathy in other diseases classified elsewhere	0.291	0.708	0.000
M49.4 Neuropathic spondylopathy	0.291	0.708	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.291	0.708	0.000
M49.2 Enterobacterial spondylitis	0.291	0.708	0.000
M49.1 Brucella spondylitis	0.291	0.708	0.000
M49.0 Tuberculosis of spine	0.291	0.708	0.000
D50.1 Sideropenic dysphagia	0.000	0.710	0.289
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.711	0.289
L44 Other papulosquamous disorders	0.000	0.711	0.289
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.711	0.289
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.711	0.289
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.712	0.288
M14.8 Arthropathies in other specified diseases classified elsewhere	0.288	0.712	0.000
M11.1 Familial chondrocalcinosis	0.288	0.712	0.000
M11.0 Hydroxyapatite deposition disease	0.288	0.712	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.287	0.713	0.000
# Top node	0.000	0.714	0.286
M13.1 Monoarthritis, not elsewhere classified	0.285	0.715	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.285	0.715	0.000
D53.9 Nutritional anaemia, unspecified	0.000	0.716	0.284
M12.24 Villonodular synovitis (pigmented) (Hand)	0.282	0.718	0.000
M11.2 Other chondrocalcinosis	0.282	0.718	0.000
G70-G73 Diseases of myoneural junction and muscle	0.000	0.719	0.281
D58 Other hereditary haemolytic anaemias	0.000	0.720	0.280
D69.2 Other nonthrombocytopenic purpura	0.000	0.724	0.276
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.724	0.276
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.275	0.724	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.275	0.724	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.275	0.724	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.275	0.724	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.275	0.724	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.275	0.724	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.275	0.724	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.275	0.724	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.275	0.724	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.275	0.725	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.726	0.274
D60.9 Acquired pure red cell aplasia, unspecified	0.000	0.727	0.273
D60.8 Other acquired pure red cell aplasias	0.000	0.727	0.273
D60.1 Transient acquired pure red cell aplasia	0.000	0.727	0.273
D60.0 Chronic acquired pure red cell aplasia	0.000	0.727	0.273
M65-M68 Disorders of synovium and tendon	0.273	0.727	0.000
L42 Pityriasis rosea	0.000	0.727	0.272
D82 Immunodeficiency associated with other major defects	0.000	0.727	0.272
M46.4 Discitis, unspecified	0.272	0.728	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.728	0.272
L10-L14 Bullous disorders	0.000	0.729	0.271
D53.8 Other specified nutritional anaemias	0.000	0.733	0.267
D53.2 Scorbutic anaemia	0.000	0.733	0.267
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.733	0.267
D53.0 Protein deficiency anaemia	0.000	0.733	0.267
M08.08 Juvenile rheumatoid arthritis (Other)	0.267	0.733	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.267	0.733	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.267	0.733	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.267	0.733	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.267	0.733	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.267	0.733	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.267	0.733	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.267	0.733	0.000
D69.8 Other specified haemorrhagic conditions	0.000	0.733	0.266
D69.1 Qualitative platelet defects	0.000	0.733	0.266
D59.1 Other autoimmune haemolytic anaemias	0.000	0.734	0.266
L50-L54 Urticaria and erythema	0.000	0.735	0.265
D55 Anaemia due to enzyme disorders	0.000	0.735	0.264
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.736	0.264
D86 Sarcoidosis	0.000	0.736	0.264
L41 Parapsoriasis	0.000	0.736	0.263
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.264	0.736	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.736	0.263
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.737	0.263
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.737	0.263
M60-M63 Disorders of muscles	0.263	0.737	0.000
G36.9 Acute disseminated demyelination, unspecified	0.000	0.739	0.260
G36.8 Other specified acute disseminated demyelination	0.000	0.739	0.260
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.739	0.260
M11.8 Other specified crystal arthropathies	0.260	0.740	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.258	0.742	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.743	0.257
G37.5 Concentric sclerosis [Balo]	0.000	0.743	0.256
G37.4 Subacute necrotising myelitis	0.000	0.743	0.256
G37.2 Central pontine myelinolysis	0.000	0.743	0.256
G37.1 Central demyelination of corpus callosum	0.000	0.743	0.256
G37.0 Diffuse sclerosis	0.000	0.743	0.256
E20-E35 Disorders of other endocrine glands	0.000	0.743	0.257
D66 Hereditary factor VIII deficiency	0.000	0.745	0.255
D69.5 Secondary thrombocytopenia	0.000	0.746	0.254
E27 Other disorders of adrenal gland	0.000	0.746	0.254
D69.0 Allergic purpura	0.000	0.746	0.254
E27.1 Primary adrenocortical insufficiency	0.000	0.747	0.253
M13.0 Polyarthritis, unspecified	0.253	0.747	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.749	0.251
M13.8 Other specified arthritis	0.251	0.749	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.751	0.249
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.751	0.249
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.751	0.249
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.751	0.249
L13 Other bullous disorders	0.000	0.751	0.249
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.752	0.248
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.754	0.246
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.755	0.245
M13.16 Monoarthritis, not elsewhere classified (Lower leg)	0.245	0.755	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.245	0.755	0.000
D57 Sickle-cell disorders	0.000	0.756	0.244
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.243	0.756	0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.242	0.757	0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.242	0.757	0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.242	0.757	0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.242	0.757	0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.242	0.757	0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.242	0.757	0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.242	0.757	0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.242	0.757	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.758	0.242
M48.99 Spondylopathy, unspecified (Site unspecified)	0.242	0.758	0.000
M12.29 Villonodular synovitis (pigmented) (Site unspecified)	0.242	0.758	0.000
M12.28 Villonodular synovitis (pigmented) (Other)	0.242	0.758	0.000
M12.27 Villonodular synovitis (pigmented) (Ankle and foot)	0.242	0.758	0.000
M12.25 Villonodular synovitis (pigmented) (Pelvic region and thigh)	0.242	0.758	0.000
M12.23 Villonodular synovitis (pigmented) (Forearm)	0.242	0.758	0.000
M12.22 Villonodular synovitis (pigmented) (Upper arm)	0.242	0.758	0.000
M12.21 Villonodular synovitis (pigmented) (Shoulder region)	0.242	0.758	0.000
M12.20 Villonodular synovitis (pigmented) (Multiple sites)	0.242	0.758	0.000
M48.4 Fatigue fracture of vertebra	0.241	0.759	0.000
M48.3 Traumatic spondylopathy	0.241	0.759	0.000
M48.2 Kissing spine	0.241	0.759	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.241	0.759	0.000
M48.8 Other specified spondylopathies	0.241	0.759	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.760	0.240
M12.39 Palindromic rheumatism (Site unspecified)	0.238	0.761	0.000
D58.0 Hereditary spherocytosis	0.000	0.762	0.238
D67 Hereditary factor IX deficiency	0.000	0.762	0.238
L53 Other erythematous conditions	0.000	0.762	0.238
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.762	0.238
D89.3 Immune reconstitution syndrome	0.000	0.762	0.238
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.763	0.237
M66 Spontaneous rupture of synovium and tendon	0.237	0.763	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.237	0.763	0.000
D84.1 Defects in the complement system	0.000	0.763	0.237
M94 Other disorders of cartilage	0.237	0.763	0.000
M10 Gout	0.236	0.764	0.000
M02 Reactive arthropathies	0.236	0.764	0.000
G36.0 Neuromyelitis optica [Devic]	0.000	0.765	0.235
L13.0 Dermatitis herpetiformis	0.000	0.766	0.234
M08.19 Juvenile ankylosing spondylitis (Site unspecified)	0.234	0.766	0.000
M08.18 Juvenile ankylosing spondylitis (Other)	0.234	0.766	0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)	0.234	0.766	0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)	0.234	0.766	0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)	0.234	0.766	0.000
M08.14 Juvenile ankylosing spondylitis (Hand)	0.234	0.766	0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)	0.234	0.766	0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)	0.234	0.766	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations