TreeWAS – Variant ID: rs387608

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	1.000
E03.9 Hypothyroidism, unspecified	0.000	1.000
E10.9 Without complications	0.000	1.000
M06.9 Rheumatoid arthritis, unspecified	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	1.000
E10-E14 Diabetes mellitus	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	1.000
E03 Other hypothyroidism	0.000	1.000
E10.3 With ophthalmic complications	0.001	0.999
M06 Other rheumatoid arthritis	0.002	0.998
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998
E11 Non-insulin-dependent diabetes mellitus	0.002	0.998
E10.1 With ketoacidosis	0.007	0.993
E11.3 With ophthalmic complications	0.013	0.987
M05-M14 Inflammatory polyarthropathies	0.017	0.983
L20-L30 Dermatitis and eczema	0.020	0.980
E05.9 Thyrotoxicosis, unspecified	0.021	0.979
Chapter XII Diseases of the skin and subcutaneous tissue	0.021	0.979
E05.0 Thyrotoxicosis with diffuse goitre	0.032	0.968
M05 Seropositive rheumatoid arthritis	0.036	0.964
L40-L45 Papulosquamous disorders	0.036	0.964
L27 Dermatitis due to substances taken internally	0.038	0.962
M06.0 Seronegative rheumatoid arthritis	0.039	0.961
E65-E68 Obesity and other hyperalimentation	0.047	0.953
L27.0 Generalised skin eruption due to drugs and medicaments	0.048	0.952
M05.9 Seropositive rheumatoid arthritis, unspecified	0.049	0.951
L40 Psoriasis	0.053	0.947
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.058	0.942
E10.5 With peripheral circulatory complications	0.062	0.938
L30 Other dermatitis	0.062	0.938
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.064	0.936
L29 Pruritus	0.069	0.931
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.072	0.928
E66 Obesity	0.080	0.920
L00-L08 Infections of the skin and subcutaneous tissue	0.083	0.917
E66.8 Other obesity	0.083	0.917
L30.9 Dermatitis, unspecified	0.086	0.914
L40.5 Arthropathic psoriasis	0.088	0.912
L57 Skin changes due to chronic exposure to nonionising radiation	0.089	0.911
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.092	0.908
E11.5 With peripheral circulatory complications	0.092	0.908
L29.0 Pruritus ani	0.113	0.887
L57.0 Actinic keratosis	0.114	0.886
E10.4 With neurological complications	0.116	0.884
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.117	0.883
E11.9 Without complications	0.119	0.881
E14 Unspecified diabetes mellitus	0.124	0.876
E10.2 With renal complications	0.127	0.873
L08 Other local infections of skin and subcutaneous tissue	0.129	0.871
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.130	0.870
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.130	0.870
M35 Other systemic involvement of connective tissue	0.137	0.863
M35.3 Polymyalgia rheumatica	0.140	0.860
M35.0 Sicca syndrome [Sjogren]	0.147	0.853
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.148	0.852
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.148	0.852
M06.3 Rheumatoid nodule	0.161	0.839
E11.2 With renal complications	0.171	0.829
H36.0 Diabetic retinopathy	0.172	0.828
L40.0 Psoriasis vulgaris	0.180	0.820
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.182	0.818
M07 Psoriatic and enteropathic arthropathies	0.184	0.816
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.185	0.815
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.188	0.812
L21 Seborrhoeic dermatitis	0.190	0.810
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.194	0.806
L02 Cutaneous abscess, furuncle and carbuncle	0.197	0.803
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.204	0.796
L43 Lichen planus	0.204	0.796
D64.9 Anaemia, unspecified	0.209	0.791
E06 Thyroiditis	0.213	0.787
E14.9 Without complications	0.215	0.785
M20-M25 Other joint disorders	0.219	0.781
D64 Other anaemias	0.220	0.780
# Top node	0.223	0.777
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.225	0.774
D60-D64 Aplastic and other anaemias	0.226	0.774
M06.98 Rheumatoid arthritis, unspecified (Other)	0.227	0.773
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.228	0.772
M14 Arthropathies in other diseases classified elsewhere	0.240	0.760
E10.6 With other specified complications	0.245	0.755
H36 Retinal disorders in diseases classified elsewhere	0.251	0.749
L40.9 Psoriasis, unspecified	0.259	0.741
E10.8 With unspecified complications	0.260	0.740
M35.1 Other overlap syndromes	0.263	0.737
M35.7 Hypermobility syndrome	0.266	0.734
E14.3 With ophthalmic complications	0.269	0.731
M10 Gout	0.274	0.726
E20-E35 Disorders of other endocrine glands	0.274	0.726
L29.8 Other pruritus	0.280	0.720
M34 Systemic sclerosis	0.281	0.719
L56 Other acute skin changes due to ultraviolet radiation	0.281	0.719
E10.7 With multiple complications	0.283	0.717
E10.0 With coma	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.283	0.717
E02 Subclinical iodine-deficiency hypothyroidism	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.283	0.717
E03.5 Myxoedema coma	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.283	0.717
M06.8 Other specified rheumatoid arthritis	0.284	0.716
M06.2 Rheumatoid bursitis	0.284	0.716
M06.1 Adult-onset Still's disease	0.284	0.716
E27 Other disorders of adrenal gland	0.284	0.716
E05.5 Thyroid crisis or storm	0.284	0.716
E05.4 Thyrotoxicosis factitia	0.284	0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.284	0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.284	0.716
E11.7 With multiple complications	0.284	0.715
E11.4 With neurological complications	0.285	0.715
E11.8 With unspecified complications	0.292	0.708
L40.8 Other psoriasis	0.294	0.706
M12 Other specific arthropathies	0.295	0.705
M09 Juvenile arthritis in diseases classified elsewhere	0.295	0.705
M08 Juvenile arthritis	0.295	0.705
L25 Unspecified contact dermatitis	0.297	0.703
L24 Irritant contact dermatitis	0.297	0.703
L26 Exfoliative dermatitis	0.297	0.703
L22 Diaper [napkin] dermatitis	0.297	0.703
M22 Disorders of patella	0.297	0.703
L20 Atopic dermatitis	0.298	0.702
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.300	0.700
L29.9 Pruritus, unspecified	0.300	0.700
L80-L99 Other disorders of the skin and subcutaneous tissue	0.302	0.698
M07.3 Other psoriatic arthropathies	0.304	0.696
M06.34 Rheumatoid nodule (Hand)	0.304	0.696
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.305	0.695
E27.1 Primary adrenocortical insufficiency	0.307	0.693
H30-H36 Disorders of choroid and retina	0.307	0.693
L50-L54 Urticaria and erythema	0.308	0.692
M05.8 Other seropositive rheumatoid arthritis	0.309	0.691
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.309	0.691
M05.2 Rheumatoid vasculitis	0.309	0.691
M05.1 Rheumatoid lung disease	0.309	0.691
M05.0 Felty's syndrome	0.309	0.691
L44 Other papulosquamous disorders	0.309	0.691
L41 Parapsoriasis	0.309	0.691
L45 Papulosquamous disorders in diseases classified elsewhere	0.309	0.691
L27.9 Dermatitis due to unspecified substance taken internally	0.311	0.689
L27.8 Dermatitis due to other substances taken internally	0.311	0.689
L27.2 Dermatitis due to ingested food	0.311	0.689
M06.08 Seronegative rheumatoid arthritis (Other)	0.311	0.689
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.311	0.689
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.311	0.689
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.311	0.689
M06.04 Seronegative rheumatoid arthritis (Hand)	0.311	0.689
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.311	0.689
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.311	0.689
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.311	0.689
E05.8 Other thyrotoxicosis	0.311	0.689
L21.9 Seborrhoeic dermatitis, unspecified	0.312	0.688
E65 Localised adiposity	0.315	0.685
E67 Other hyperalimentation	0.316	0.684
E68 Sequelae of hyperalimentation	0.316	0.684
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.318	0.682
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.318	0.682
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.318	0.682
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.318	0.682
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.318	0.682
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.318	0.682
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.318	0.682
L10-L14 Bullous disorders	0.321	0.679
L40.4 Guttate psoriasis	0.321	0.679
L40.3 Pustulosis palmaris et plantaris	0.321	0.679
L40.2 Acrodermatitis continua	0.321	0.679
L40.1 Generalised pustular psoriasis	0.321	0.679
M06.4 Inflammatory polyarthropathy	0.324	0.675
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.324	0.676
L58 Radiodermatitis	0.324	0.676
L55 Sunburn	0.324	0.676
L30.5 Pityriasis alba	0.328	0.672
L30.4 Erythema intertrigo	0.328	0.672
L30.3 Infective dermatitis	0.328	0.672
L30.2 Cutaneous autosensitisation	0.328	0.672
L30.1 Dyshidrosis [pompholyx]	0.328	0.672
L30.0 Nummular dermatitis	0.328	0.672
E11.1 With ketoacidosis	0.330	0.670
E11.0 With coma	0.330	0.670
L29.3 Anogenital pruritus, unspecified	0.332	0.667
L29.1 Pruritus scroti	0.332	0.667
L43.8 Other lichen planus	0.333	0.667
Chapter VII Diseases of the eye and adnexa	0.333	0.667
M31 Other necrotising vasculopathies	0.336	0.664
E06.3 Autoimmune thyroiditis	0.338	0.662
L23 Allergic contact dermatitis	0.340	0.660
E66.1 Drug-induced obesity	0.340	0.660
L42 Pityriasis rosea	0.342	0.658
L01 Impetigo	0.342	0.658
L00 Staphylococcal scalded skin syndrome	0.342	0.658
D50-D53 Nutritional anaemias	0.342	0.658
D61 Other aplastic anaemias	0.345	0.655
E11.6 With other specified complications	0.346	0.654
L28 Lichen simplex chronicus and prurigo	0.346	0.654
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.347	0.653
L57.5 Actinic granuloma	0.347	0.653
L57.3 Poikiloderma of Civatte	0.347	0.653
L57.2 Cutis rhomboidalis nuchae	0.347	0.653
L57.1 Actinic reticuloid	0.347	0.653
L97 Ulcer of lower limb, not elsewhere classified	0.348	0.652
M06.37 Rheumatoid nodule (Ankle and foot)	0.350	0.650
L92 Granulomatous disorders of skin and subcutaneous tissue	0.355	0.645
L29.2 Pruritus vulvae	0.366	0.634
M22.2 Patellofemoral disorders	0.367	0.633
M13 Other arthritis	0.368	0.632
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.370	0.629
E14.8 With unspecified complications	0.372	0.628
E14.7 With multiple complications	0.372	0.628
E14.6 With other specified complications	0.372	0.628
E14.5 With peripheral circulatory complications	0.372	0.628
E14.1 With ketoacidosis	0.372	0.628
E14.0 With coma	0.372	0.628
L57.4 Cutis laxa senilis	0.373	0.627
M34.1 CR(E)ST syndrome	0.373	0.627
H35 Other retinal disorders	0.373	0.627
L08.1 Erythrasma	0.376	0.624
L08.0 Pyoderma	0.376	0.624
E50-E64 Other nutritional deficiencies	0.377	0.623
E40-E46 Malnutrition	0.379	0.621
E66.0 Obesity due to excess calories	0.381	0.619
M35.9 Systemic involvement of connective tissue, unspecified	0.381	0.618
M35.8 Other specified systemic involvement of connective tissue	0.381	0.618
M35.6 Relapsing panniculitis [Weber-Christian]	0.381	0.618
M35.5 Multifocal fibrosclerosis	0.381	0.618
M35.4 Diffuse (eosinophilic) fasciitis	0.381	0.618
M31.3 Wegener's granulomatosis	0.384	0.616
E13 Other specified diabetes mellitus	0.385	0.615
E20 Hypoparathyroidism	0.385	0.615
L04 Acute lymphadenitis	0.385	0.614
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.387	0.613
E27.4 Other and unspecified adrenocortical insufficiency	0.391	0.609
H35.3 Degeneration of macula and posterior pole	0.396	0.604
M06.39 Rheumatoid nodule (Site unspecified)	0.398	0.602
M06.38 Rheumatoid nodule (Other)	0.398	0.602
M06.36 Rheumatoid nodule (Lower leg)	0.398	0.602
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.398	0.602
M06.33 Rheumatoid nodule (Forearm)	0.398	0.602
M06.32 Rheumatoid nodule (Upper arm)	0.398	0.602
M06.31 Rheumatoid nodule (Shoulder region)	0.398	0.602
M06.30 Rheumatoid nodule (Multiple sites)	0.398	0.602
M34.9 Systemic sclerosis, unspecified	0.399	0.601
E27.8 Other specified disorders of adrenal gland	0.399	0.601
M14.6 Neuropathic arthropathy	0.399	0.600
L27.1 Localised skin eruption due to drugs and medicaments	0.402	0.598
E27.2 Addisonian crisis	0.409	0.591
M11 Other crystal arthropathies	0.409	0.591
E14.4 With neurological complications	0.409	0.591
L30.8 Other specified dermatitis	0.410	0.590
M30 Polyarteritis nodosa and related conditions	0.411	0.589
L83 Acanthosis nigricans	0.414	0.586
L43.9 Lichen planus, unspecified	0.414	0.586
M07.6 Other enteropathic arthropathies	0.415	0.585
M07.5 Arthropathy in ulcerative colitis	0.415	0.585
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.415	0.585
M07.2 Psoriatic spondylitis	0.415	0.585
M07.1 Arthritis mutilans	0.415	0.585
M07.0 Distal interphalangeal psoriatic arthropathy	0.415	0.585
M07.30 Other psoriatic arthropathies (Multiple sites)	0.417	0.583
H53-H54 Visual disturbances and blindness	0.418	0.582
L21.8 Other seborrhoeic dermatitis	0.419	0.581
L21.1 Seborrhoeic infantile dermatitis	0.419	0.581
L21.0 Seborrhoea capitis	0.419	0.581
L03 Cellulitis	0.421	0.579
M33 Dermatopolymyositis	0.424	0.576
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.424	0.575
M10.9 Gout, unspecified	0.426	0.574
L43.3 Subacute (active) lichen planus	0.429	0.571
L43.2 Lichenoid drug reaction	0.429	0.571
L43.1 Bullous lichen planus	0.429	0.571
L43.0 Hypertrophic lichen planus	0.429	0.571
D51 Vitamin B12 deficiency anaemia	0.429	0.571
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.430	0.570
L50 Urticaria	0.430	0.570
M22.3 Other derangements of patella	0.430	0.570
M35.2 Behcet's disease	0.430	0.570
D61.9 Aplastic anaemia, unspecified	0.430	0.569
E06.5 Other chronic thyroiditis	0.435	0.564
E06.4 Drug-induced thyroiditis	0.435	0.564
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.435	0.564
E06.1 Subacute thyroiditis	0.435	0.564
E06.0 Acute thyroiditis	0.435	0.564
L91 Hypertrophic disorders of skin	0.436	0.564
M13.0 Polyarthritis, unspecified	0.440	0.560
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.440	0.560
D64.4 Congenital dyserythropoietic anaemia	0.440	0.560
D64.3 Other sideroblastic anaemias	0.440	0.560
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.440	0.560
D64.1 Secondary sideroblastic anaemia due to disease	0.440	0.560
D64.0 Hereditary sideroblastic anaemia	0.440	0.560
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.441	0.559
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.442	0.558
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.443	0.557
Chapter XVI Certain conditions originating in the perinatal period	0.443	0.557
M32 Systemic lupus erythematosus	0.444	0.556
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.445	0.555
L05 Pilonidal cyst	0.446	0.554
D64.8 Other specified anaemias	0.447	0.553
H35.4 Peripheral retinal degeneration	0.449	0.551
M34.8 Other forms of systemic sclerosis	0.450	0.550
L95 Vasculitis limited to skin, not elsewhere classified	0.451	0.549
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.451	0.549
M14.8 Arthropathies in other specified diseases classified elsewhere	0.455	0.545
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.455	0.545
M14.4 Arthropathy in amyloidosis	0.455	0.545
M14.3 Lipoid dermatoarthritis	0.455	0.545
M14.2 Diabetic arthropathy	0.455	0.545
M14.1 Crystal arthropathy in other metabolic disorders	0.455	0.545
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.455	0.545
H53 Visual disturbances	0.455	0.545
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.459	0.541
M07.39 Other psoriatic arthropathies (Site unspecified)	0.463	0.537
H36.8 Other retinal disorders in diseases classified elsewhere	0.463	0.537
Chapter VI Diseases of the nervous system	0.464	0.536
D55-D59 Haemolytic anaemias	0.464	0.536
E66.2 Extreme obesity with alveolar hypoventilation	0.465	0.535
E20.9 Hypoparathyroidism, unspecified	0.465	0.535
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.472	0.528
M13.00 Polyarthritis, unspecified (Multiple sites)	0.475	0.525
M10.4 Other secondary gout	0.479	0.521
M10.3 Gout due to impairment of renal function	0.479	0.521
M10.2 Drug-induced gout	0.479	0.521
M10.1 Lead-induced gout	0.479	0.521
E35 Disorders of endocrine glands in diseases classified elsewhere	0.479	0.521
E32 Diseases of thymus	0.479	0.521
E31 Polyglandular dysfunction	0.479	0.521
E30 Disorders of puberty, not elsewhere classified	0.479	0.521
E14.2 Withrenal complications	0.480	0.520
M22.8 Other disorders of patella	0.482	0.518
M34.2 Systemic sclerosis induced by drugs and chemicals	0.484	0.516
M34.0 Progressive systemic sclerosis	0.484	0.516
E07 Other disorders of thyroid	0.484	0.515
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.484	0.515
L56.4 Polymorphous light eruption	0.484	0.515
L56.3 Solar urticaria	0.484	0.515
L56.2 Photocontact dermatitis [berloque dermatitis]	0.484	0.515
L56.1 Drug photoallergic response	0.484	0.515
L56.0 Drug phototoxic response	0.484	0.515
E06.9 Thyroiditis, unspecified	0.484	0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.486	0.514
E12.9 Without complications	0.486	0.514
E12.8 With unspecified complications	0.486	0.514
E12.7 With multiple complications	0.486	0.514
E12.6 With other specified complications	0.486	0.514
E12.5 With peripheral circulatory complications	0.486	0.514
E12.4 With neurological complications	0.486	0.514
E12.3 With ophthalmic complications	0.486	0.514
E12.2 With renal complications	0.486	0.514
E12.1 With ketoacidosis	0.486	0.514
E12.0 With coma	0.486	0.514
L94 Other localised connective tissue disorders	0.486	0.514
M06.19 Adult-onset Still's disease (Site unspecified)	0.487	0.513
M06.18 Adult-onset Still's disease (Other)	0.487	0.513
M06.17 Adult-onset Still's disease (Ankle and foot)	0.487	0.513
M06.16 Adult-onset Still's disease (Lower leg)	0.487	0.513
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.487	0.513
M06.14 Adult-onset Still's disease (Hand)	0.487	0.513
M06.13 Adult-onset Still's disease (Forearm)	0.487	0.513
M06.12 Adult-onset Still's disease (Upper arm)	0.487	0.513
M06.11 Adult-onset Still's disease (Shoulder region)	0.487	0.513
M06.10 Adult-onset Still's disease (Multiple sites)	0.487	0.513
M06.29 Rheumatoid bursitis (Site unspecified)	0.487	0.513
M06.28 Rheumatoid bursitis (Other)	0.487	0.513
M06.27 Rheumatoid bursitis (Ankle and foot)	0.487	0.513
M06.26 Rheumatoid bursitis (Lower leg)	0.487	0.513
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.487	0.513
M06.24 Rheumatoid bursitis (Hand)	0.487	0.513
M06.23 Rheumatoid bursitis (Forearm)	0.487	0.513
M06.22 Rheumatoid bursitis (Upper arm)	0.487	0.513
M06.21 Rheumatoid bursitis (Shoulder region)	0.487	0.513
M06.20 Rheumatoid bursitis (Multiple sites)	0.487	0.513
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.487	0.513
M06.88 Other specified rheumatoid arthritis (Other)	0.487	0.513
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.487	0.513
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.487	0.513
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.487	0.513
M06.84 Other specified rheumatoid arthritis (Hand)	0.487	0.513
M06.83 Other specified rheumatoid arthritis (Forearm)	0.487	0.513
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.487	0.513
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.487	0.513
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.487	0.513
E27.5 Adrenomedullary hyperfunction	0.487	0.513
E27.3 Drug-induced adrenocortical insufficiency	0.487	0.513
E27.0 Other adrenocortical overactivity	0.487	0.513
E28 Ovarian dysfunction	0.487	0.513
M07.36 Other psoriatic arthropathies (Lower leg)	0.488	0.511
G90-G99 Other disorders of the nervous system	0.490	0.510
H53.9 Visual disturbance, unspecified	0.490	0.510
L50.0 Allergic urticaria	0.490	0.510
M08.9 Juvenile arthritis, unspecified	0.495	0.505
M08.8 Other juvenile arthritis	0.495	0.505
M08.4 Pauciarticular juvenile arthritis	0.495	0.505
M08.3 Juvenile polyarthritis (seronegative)	0.495	0.505
M08.2 Juvenile arthritis with systemic onset	0.495	0.505
M08.1 Juvenile ankylosing spondylitis	0.495	0.505
M08.0 Juvenile rheumatoid arthritis	0.495	0.505
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.495	0.505
M09.2 Juvenile arthritis in ulcerative colitis	0.495	0.505
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.495	0.505
M09.0 Juvenile arthritis in psoriasis	0.495	0.505
M12.8 Other specific arthropathies, not elsewhere classified	0.495	0.505
M12.5 Traumatic arthropathy	0.495	0.505
M12.4 Intermittent hydrarthrosis	0.495	0.505
M12.3 Palindromic rheumatism	0.495	0.505
M12.2 Villonodular synovitis (pigmented)	0.495	0.505
M12.1 Kaschin-Beck disease	0.495	0.505
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.495	0.505
M22.4 Chondromalacia patellae	0.495	0.505
L24.9 Irritant contact dermatitis, unspecified cause	0.496	0.504
L24.8 Irritant contact dermatitis due to other agents	0.496	0.504
L24.7 Irritant contact dermatitis due to plants, except food	0.496	0.504
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.496	0.504
L24.5 Irritant contact dermatitis due to other chemical products	0.496	0.504
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.496	0.504
L24.3 Irritant contact dermatitis due to cosmetics	0.496	0.504
L24.2 Irritant contact dermatitis due to solvents	0.496	0.504
L24.1 Irritant contact dermatitis due to oils and greases	0.496	0.504
L24.0 Irritant contact dermatitis due to detergents	0.496	0.504
L25.9 Unspecified contact dermatitis, unspecified cause	0.496	0.504
L25.8 Unspecified contact dermatitis due to other agents	0.496	0.504
L25.5 Unspecified contact dermatitis due to plants, except food	0.496	0.504
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.496	0.504
L25.3 Unspecified contact dermatitis due to other chemical products	0.496	0.504
L25.2 Unspecified contact dermatitis due to dyes	0.496	0.504
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.496	0.504
L25.0 Unspecified contact dermatitis due to cosmetics	0.496	0.504
M22.1 Recurrent subluxation of patella	0.496	0.504
G91 Hydrocephalus	0.496	0.504
L20.8 Other atopic dermatitis	0.497	0.503
L20.0 Besnier's prurigo	0.497	0.503
E15 Nondiabetic hypoglycaemic coma	0.498	0.502
L20.9 Atopic dermatitis, unspecified	0.498	0.502
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.499	0.500
L87 Transepidermal elimination disorders	0.499	0.500
L88 Pyoderma gangrenosum	0.499	0.500
L86 Keratoderma in diseases classified elsewhere	0.499	0.500
M07.38 Other psoriatic arthropathies (Other)	0.501	0.499
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.501	0.499
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.501	0.499
M07.34 Other psoriatic arthropathies (Hand)	0.501	0.499
M07.33 Other psoriatic arthropathies (Forearm)	0.501	0.499
M07.32 Other psoriatic arthropathies (Upper arm)	0.501	0.499
M07.31 Other psoriatic arthropathies (Shoulder region)	0.501	0.499
G91.9 Hydrocephalus, unspecified	0.501	0.499
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.503	0.497
H32 Chorioretinal disorders in diseases classified elsewhere	0.503	0.497
H30 Chorioretinal inflammation	0.503	0.497
L54 Erythema in diseases classified elsewhere	0.504	0.496
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.504	0.496
M05.09 Felty's syndrome (Site unspecified)	0.504	0.496
M05.08 Felty's syndrome (Other)	0.504	0.496
M05.07 Felty's syndrome (Ankle and foot)	0.504	0.496
M05.06 Felty's syndrome (Lower leg)	0.504	0.496
M05.05 Felty's syndrome (Pelvic region and thigh)	0.504	0.496
M05.04 Felty's syndrome (Hand)	0.504	0.496
M05.03 Felty's syndrome (Forearm)	0.504	0.496
M05.02 Felty's syndrome (Upper arm)	0.504	0.496
M05.01 Felty's syndrome (Shoulder region)	0.504	0.496
M05.00 Felty's syndrome (Multiple sites)	0.504	0.496
M05.19 Rheumatoid lung disease (Site unspecified)	0.504	0.496
M05.18 Rheumatoid lung disease (Other)	0.504	0.496
M05.17 Rheumatoid lung disease (Ankle and foot)	0.504	0.496
M05.16 Rheumatoid lung disease (Lower leg)	0.504	0.496
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.504	0.496
M05.14 Rheumatoid lung disease (Hand)	0.504	0.496
M05.13 Rheumatoid lung disease (Forearm)	0.504	0.496
M05.12 Rheumatoid lung disease (Upper arm)	0.504	0.496
M05.11 Rheumatoid lung disease (Shoulder region)	0.504	0.496
M05.10 Rheumatoid lung disease (Multiple sites)	0.504	0.496
M05.29 Rheumatoid vasculitis (Site unspecified)	0.504	0.496
M05.28 Rheumatoid vasculitis (Other)	0.504	0.496
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.504	0.496
M05.26 Rheumatoid vasculitis (Lower leg)	0.504	0.496
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.504	0.496
M05.24 Rheumatoid vasculitis (Hand)	0.504	0.496
M05.23 Rheumatoid vasculitis (Forearm)	0.504	0.496
M05.22 Rheumatoid vasculitis (Upper arm)	0.504	0.496
M05.21 Rheumatoid vasculitis (Shoulder region)	0.504	0.496
M05.20 Rheumatoid vasculitis (Multiple sites)	0.504	0.496
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.504	0.496
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.504	0.496
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.504	0.496
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.504	0.496
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.504	0.496
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.504	0.496
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.504	0.496
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.504	0.496
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.504	0.496
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.504	0.496
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.504	0.496

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations