TreeWAS – Variant ID: rs3899697

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D69.6 Thrombocytopenia, unspecified	0.093	0.907	0.000
D69 Purpura and other haemorrhagic conditions	0.090	0.910	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.079	0.921	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.079	0.921	0.000
D68.9 Coagulation defect, unspecified	0.079	0.921	0.000
D68 Other coagulation defects	0.078	0.922	0.000
D69.4 Other primary thrombocytopenia	0.074	0.926	0.000
D69.9 Haemorrhagic condition, unspecified	0.073	0.927	0.000
D68.5 Primary Thrombophilia	0.073	0.927	0.000
D69.2 Other nonthrombocytopenic purpura	0.070	0.930	0.000
D66 Hereditary factor VIII deficiency	0.066	0.934	0.000
D69.0 Allergic purpura	0.064	0.936	0.000
D68.1 Hereditary factor XI deficiency	0.063	0.937	0.000
D69.8 Other specified haemorrhagic conditions	0.063	0.937	0.000
D68.0 Von Willebrand's disease	0.062	0.938	0.000
D69.1 Qualitative platelet defects	0.061	0.939	0.000
D69.5 Secondary thrombocytopenia	0.058	0.942	0.000
D68.4 Acquired coagulation factor deficiency	0.057	0.943	0.000
D67 Hereditary factor IX deficiency	0.056	0.944	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.047	0.952	0.000
D68.6 Other Thrombophilia	0.045	0.955	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.044	0.956	0.000
D68.8 Other specified coagulation defects	0.042	0.958	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.032	0.968	0.000
M81.9 Osteoporosis, unspecified	0.019	0.981	0.000
M81.98 Osteoporosis, unspecified (Other)	0.019	0.981	0.000
I77.1 Stricture of artery	0.017	0.983	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.017	0.983	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.015	0.985	0.000
D68.2 Hereditary deficiency of other clotting factors	0.014	0.985	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.014	0.985	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.014	0.986	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.014	0.986	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.987	0.013
I77 Other disorders of arteries and arterioles	0.012	0.988	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.012	0.988	0.000
C81.9 Hodgkin's disease, unspecified	0.011	0.989	0.000
I77.8 Other specified disorders of arteries and arterioles	0.011	0.989	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.010	0.989	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.010	0.990	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.010	0.990	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.990	0.010
L89.9 Decubitus ulcer and pressure area, unspecified	0.000	0.990	0.010
L89 Decubitus ulcer	0.000	0.990	0.010
I77.2 Rupture of artery	0.009	0.991	0.000
I77.5 Necrosis of artery	0.009	0.991	0.000
I77.4 Coeliac artery compression syndrome	0.009	0.991	0.000
I77.3 Arterial fibromuscular dysplasia	0.009	0.991	0.000
C81 Hodgkin's disease	0.009	0.991	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.991	0.009
L89.1 Stage II decubitus ulcer	0.000	0.992	0.008
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.992	0.008
L89.2 Stage III decubitus ulcer	0.000	0.992	0.008
I77.0 Arteriovenous fistula, acquired	0.008	0.992	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.008	0.992	0.000
T18.1 Foreign body in oesophagus	0.000	0.992	0.008
C81.1 Nodular sclerosis	0.008	0.992	0.000
C81.0 Lymphocytic predominance	0.007	0.993	0.000
I77.6 Arteritis, unspecified	0.007	0.993	0.000
C81.7 Other Hodgkin's disease	0.007	0.993	0.000
C81.2 Mixed cellularity	0.007	0.993	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.006	0.993	0.000
C81.3 Lymphocytic depletion	0.006	0.993	0.000
S70 Superficial injury of hip and thigh	0.000	0.993	0.007
M81.99 Osteoporosis, unspecified (Site unspecified)	0.006	0.994	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.006	0.994	0.000
O21.0 Mild hyperemesis gravidarum	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.006	0.994	0.000
S70.0 Contusion of hip	0.000	0.994	0.006
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O14.0 Moderate preeclampsia	0.005	0.995	0.000
I74.5 Embolism and thrombosis of iliac artery	0.005	0.995	0.000
O12.1 Gestational proteinuria	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.005	0.995	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.005	0.995	0.000
O12.0 Gestational oedema	0.005	0.995	0.000
O14.1 Severe preeclampsia	0.005	0.995	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.995	0.005
O21.2 Late vomiting of pregnancy	0.005	0.995	0.000
O21 Excessive vomiting in pregnancy	0.005	0.995	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.005	0.995	0.000
S70.8 Other superficial injuries of hip and thigh	0.000	0.995	0.005
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O12.2 Gestational oedema with proteinuria	0.005	0.995	0.000
S70.1 Contusion of thigh	0.000	0.995	0.005
H35.5 Hereditary retinal dystrophy	0.000	0.995	0.005
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
O14.2 HELLP syndrome	0.004	0.996	0.000
D55-D59 Haemolytic anaemias	0.004	0.996	0.000
I74 Arterial embolism and thrombosis	0.004	0.996	0.000
O15 Eclampsia	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
I72.3 Aneurysm of iliac artery	0.004	0.996	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.996	0.004
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.004	0.996	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.996	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.004	0.996	0.000
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
T18 Foreign body in alimentary tract	0.000	0.996	0.004
I70-I79 Diseases of arteries, arterioles and capillaries	0.004	0.996	0.000
S52.6 Fracture of lower end of both ulna and radius	0.004	0.996	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.004	0.996	0.000
H35.2 Other proliferative retinopathy	0.000	0.996	0.004
D57 Sickle-cell disorders	0.004	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.004	0.996	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.004	0.996	0.000
D59 Acquired haemolytic anaemia	0.004	0.996	0.000
O23 Infections of genito-urinary tract in pregnancy	0.004	0.996	0.000
O21.8 Other vomiting complicating pregnancy	0.003	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.000	0.996	0.004
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.996	0.004
H52.3 Anisometropia and aniseikonia	0.003	0.996	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
H35 Other retinal disorders	0.000	0.997	0.003
T18.2 Foreign body in stomach	0.000	0.997	0.003
T18.0 Foreign body in mouth	0.000	0.997	0.003
I74.9 Embolism and thrombosis of unspecified artery	0.003	0.997	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D55 Anaemia due to enzyme disorders	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.000	0.997	0.003
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.003	0.997	0.000
D57.1 Sickle-cell anaemia without crisis	0.003	0.997	0.000
O15.9 Eclampsia, unspecified as to time period	0.003	0.997	0.000
O15.2 Eclampsia in the puerperium	0.003	0.997	0.000
O15.1 Eclampsia in labour	0.003	0.997	0.000
O15.0 Eclampsia in pregnancy	0.003	0.997	0.000
M54.37 Sciatica (Lumbosacral region)	0.000	0.997	0.003
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
I72 Other aneurysm	0.003	0.997	0.000
O22 Venous complications in pregnancy	0.003	0.997	0.000
G41.9 Status epilepticus, unspecified	0.003	0.997	0.000
G62.8 Other specified polyneuropathies	0.003	0.997	0.000
H35.9 Retinal disorder, unspecified	0.000	0.997	0.003
M81.3 Postsurgical malabsorption osteoporosis	0.003	0.997	0.000
O28 Abnormal findings on antenatal screening of mother	0.003	0.997	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.003	0.997	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.003	0.997	0.000
D56 Thalassaemia	0.003	0.997	0.000
T18.5 Foreign body in anus and rectum	0.000	0.997	0.003
D59.1 Other autoimmune haemolytic anaemias	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.003	0.997	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.003	0.997	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.003	0.997	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.003	0.997	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.997	0.003
T18.4 Foreign body in colon	0.000	0.997	0.003
D61 Other aplastic anaemias	0.003	0.997	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.003	0.997	0.000
I78 Diseases of capillaries	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.003	0.997	0.000
O25 Malnutrition in pregnancy	0.003	0.997	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
D60-D64 Aplastic and other anaemias	0.003	0.997	0.000
D57.8 Other sickle-cell disorders	0.003	0.997	0.000
D57.3 Sickle-cell trait	0.003	0.997	0.000
D57.2 Double heterozygous sickling disorders	0.003	0.997	0.000
D57.0 Sickle-cell anaemia with crisis	0.003	0.997	0.000
O23.0 Infections of kidney in pregnancy	0.003	0.997	0.000
D58 Other hereditary haemolytic anaemias	0.003	0.997	0.000
M23.49 Loose body in knee-Unspec lig/men	0.003	0.997	0.000
O22.4 Haemorrhoids in pregnancy	0.003	0.997	0.000
D59.8 Other acquired haemolytic anaemias	0.003	0.997	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.003	0.997	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.003	0.997	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.003	0.997	0.000
D59.3 Haemolytic-uraemic syndrome	0.003	0.997	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.003	0.997	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.003	0.997	0.000
O23.2 Infections of urethra in pregnancy	0.003	0.997	0.000
O23.1 Infections of bladder in pregnancy	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
D12.2 Ascending colon	0.000	0.997	0.003
H52.0 Hypermetropia	0.003	0.997	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.003	0.997	0.000
N64.8 Other specified disorders of breast	0.000	0.997	0.003
D59.9 Acquired haemolytic anaemia, unspecified	0.003	0.997	0.000
T18.3 Foreign body in small intestine	0.000	0.997	0.003
I74.8 Embolism and thrombosis of other arteries	0.003	0.997	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.003	0.997	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.997	0.003
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
I72.2 Aneurysm of renal artery	0.003	0.997	0.000
D61.1 Drug-induced aplastic anaemia	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.000	0.997	0.003
I72.0 Aneurysm of carotid artery	0.003	0.997	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.003	0.997	0.000
H35.1 Retinopathy of prematurity	0.000	0.997	0.003
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
D61.9 Aplastic anaemia, unspecified	0.003	0.997	0.000
D61.0 Constitutional aplastic anaemia	0.003	0.997	0.000
O22.1 Genital varices in pregnancy	0.003	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
H52 Disorders of refraction and accommodation	0.003	0.997	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.002	0.997	0.000
D55.8 Other anaemias due to enzyme disorders	0.002	0.997	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.002	0.997	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.002	0.997	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.002	0.997	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.002	0.997	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
H52.7 Disorder of refraction, unspecified	0.003	0.997	0.000
I79.1 Aortitis in diseases classified elsewhere	0.002	0.997	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.002	0.997	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.003	0.997	0.000
D56.3 Thalassaemia trait	0.002	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.88 Other osteoporosis (Other)	0.002	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.997	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.002	0.997	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.002	0.997	0.000
O22.9 Venous complication in pregnancy, unspecified	0.002	0.997	0.000
O22.8 Other venous complications in pregnancy	0.002	0.997	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.002	0.997	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.002	0.997	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.002	0.997	0.000
Y60.4 During endoscopic examination	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.997	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.002	0.997	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.002	0.997	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.002	0.997	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.002	0.997	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.002	0.997	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.997	0.003
H35.7 Separation of retinal layers	0.000	0.997	0.003
D56.9 Thalassaemia, unspecified	0.002	0.997	0.000
D56.8 Other thalassaemias	0.002	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.002	0.997	0.000
D56.2 Delta-beta thalassaemia	0.002	0.997	0.000
D56.0 Alpha thalassaemia	0.002	0.997	0.000
I72.9 Aneurysm of unspecified site	0.002	0.997	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.997	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.002	0.997	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.002	0.997	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.002	0.997	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.002	0.997	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.002	0.997	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.003	0.997	0.000
D61.8 Other specified aplastic anaemias	0.002	0.997	0.000
D61.3 Idiopathic aplastic anaemia	0.002	0.997	0.000
D61.2 Aplastic anaemia due to other external agents	0.002	0.997	0.000
D76.3 Other histiocytosis syndromes	0.002	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.997	0.000
K42 Umbilical hernia	0.002	0.997	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.998	0.000
I78.9 Disease of capillaries, unspecified	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.002	0.998	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.6 Failed or difficult intubation during pregnancy	0.002	0.998	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.002	0.998	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.002	0.998	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.002	0.998	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.002	0.998	0.000
D58.1 Hereditary elliptocytosis	0.002	0.998	0.000
D58.2 Other haemoglobinopathies	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
D50-D53 Nutritional anaemias	0.002	0.998	0.000
I78.8 Other diseases of capillaries	0.002	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
I72.1 Aneurysm of artery of upper extremity	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
H52.4 Presbyopia	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.998	0.002
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
G63.2 Diabetic polyneuropathy	0.002	0.998	0.000
H52.6 Other disorders of refraction	0.002	0.998	0.000
H52.5 Disorders of accommodation	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.002	0.998	0.000
H11.9 Disorder of conjunctiva, unspecified	0.002	0.998	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.998	0.002
M23.4 Loose body in knee	0.002	0.998	0.000
C50.2 Upper-inner quadrant of breast	0.000	0.998	0.002
D56.1 Beta thalassaemia	0.002	0.998	0.000
D58.0 Hereditary spherocytosis	0.002	0.998	0.000
D53 Other nutritional anaemias	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
D83 Common variable immunodeficiency	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.002	0.998	0.000
M23.40 Loose body in knee-Mult sites	0.002	0.998	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
Z48.9 Surgical follow-up care, unspecified	0.000	0.998	0.002
O97 Death from sequelae of direct obstetric causes	0.002	0.998	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.002	0.998	0.000
O95 Obstetric death of unspecified cause	0.002	0.998	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M23.46 Loose body in knee-O/unsp lat men	0.002	0.998	0.000
K42.1 Umbilical hernia with gangrene	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.998	0.000
C62.9 Testis, unspecified	0.002	0.998	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.998	0.002
A49.0 Staphylococcal infection, unspecified	0.000	0.998	0.002
D53.9 Nutritional anaemia, unspecified	0.002	0.998	0.000
M47.8 Other spondylosis	0.000	0.998	0.002
S52.10 Fracture of upper end of radius (closed)	0.000	0.998	0.002
D60.8 Other acquired pure red cell aplasias	0.002	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.002	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
H35.6 Retinal haemorrhage	0.000	0.998	0.002
D60.9 Acquired pure red cell aplasia, unspecified	0.002	0.998	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
D72 Other disorders of white blood cells	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.002	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.002	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.002	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.002	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.002	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.002	0.998	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.002	0.998	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.002	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.998	0.002
Z48.8 Other specified surgical follow-up care	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
D50.8 Other iron deficiency anaemias	0.002	0.998	0.000
M23.47 Loose body in knee-Capsular lig	0.002	0.998	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.002	0.998	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.002	0.998	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.001	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.998	0.002
V23.4 Driver injured in traffic accident	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.002	0.998	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.998	0.002
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
D35.0 Adrenal gland	0.000	0.998	0.002
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
W18.5 Trade and service area	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.998	0.000
D14.3 Bronchus and lung	0.000	0.998	0.002
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
H50.2 Vertical strabismus	0.002	0.998	0.000
D72.1 Eosinophilia	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
D64 Other anaemias	0.002	0.998	0.000
G62 Other polyneuropathies	0.002	0.998	0.000
D72.9 Disorder of white blood cells, unspecified	0.001	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
D14.4 Respiratory system, unspecified	0.000	0.998	0.001
D14.2 Trachea	0.000	0.998	0.001
D81.9 Combined immunodeficiency, unspecified	0.001	0.998	0.000
D81.8 Other combined immunodeficiencies	0.001	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.001	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.001	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.001	0.998	0.000
D81.4 Nezelof's syndrome	0.001	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.001	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations