TreeWAS – Variant ID: rs3905706

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D89.2 Hypergammaglobulinaemia, unspecified	0.272	0.728	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.270	0.730	0.000
D80-D89 Certain disorders involving the immune mechanism	0.262	0.738	0.000
D80 Immunodeficiency with predominantly antibody defects	0.254	0.746	0.000
D86 Sarcoidosis	0.244	0.756	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.235	0.765	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.221	0.779	0.000
D89.1 Cryoglobulinaemia	0.217	0.783	0.000
D86.8 Sarcoidosis of other and combined sites	0.212	0.788	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.210	0.790	0.000
D84 Other immunodeficiencies	0.205	0.795	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.205	0.795	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.203	0.797	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.196	0.804	0.000
D86.0 Sarcoidosis of lung	0.194	0.806	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.193	0.807	0.000
D89.3 Immune reconstitution syndrome	0.193	0.807	0.000
D83 Common variable immunodeficiency	0.189	0.811	0.000
D82 Immunodeficiency associated with other major defects	0.188	0.812	0.000
D81 Combined immunodeficiencies	0.188	0.812	0.000
D86.3 Sarcoidosis of skin	0.187	0.813	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.186	0.814	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.182	0.818	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.182	0.818	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.182	0.818	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.182	0.818	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.182	0.818	0.000
D86.9 Sarcoidosis, unspecified	0.181	0.819	0.000
D86.1 Sarcoidosis of lymph nodes	0.181	0.819	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.169	0.831	0.000
D84.1 Defects in the complement system	0.169	0.831	0.000
D84.8 Other specified immunodeficiencies	0.158	0.842	0.000
C15.9 Oesophagus, unspecified	0.151	0.849	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.147	0.853	0.000
C15 Malignant neoplasm of oesophagus	0.146	0.854	0.000
C25.9 Pancreas, unspecified	0.145	0.855	0.000
C25 Malignant neoplasm of pancreas	0.139	0.861	0.000
C15.5 Lower third of oesophagus	0.137	0.863	0.000
D83.9 Common variable immunodeficiency, unspecified	0.136	0.863	0.000
D83.8 Other common variable immunodeficiencies	0.136	0.864	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.136	0.864	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.136	0.864	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.136	0.864	0.000
D81.9 Combined immunodeficiency, unspecified	0.135	0.865	0.000
D81.8 Other combined immunodeficiencies	0.135	0.865	0.000
D81.7 Major histocompatibility complex class II deficiency	0.135	0.865	0.000
D81.6 Major histocompatibility complex class I deficiency	0.135	0.865	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.135	0.865	0.000
D81.4 Nezelof's syndrome	0.135	0.865	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.135	0.865	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.135	0.865	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.135	0.865	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.135	0.865	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.135	0.865	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.135	0.865	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.135	0.865	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.135	0.865	0.000
D82.2 Immunodeficiency with short-limbed stature	0.135	0.865	0.000
D82.1 Di George's syndrome	0.135	0.865	0.000
D82.0 Wiskott-Aldrich syndrome	0.135	0.865	0.000
C15-C26 Malignant neoplasms of digestive organs	0.133	0.867	0.000
C16 Malignant neoplasm of stomach	0.133	0.867	0.000
C16.9 Stomach, unspecified	0.130	0.870	0.000
D84.9 Immunodeficiency, unspecified	0.124	0.876	0.000
C16.0 Cardia	0.113	0.887	0.000
C25.1 Body of pancreas	0.108	0.892	0.000
C25.4 Endocrine pancreas	0.108	0.892	0.000
C23 Malignant neoplasm of gallbladder	0.106	0.894	0.000
C25.3 Pancreatic duct	0.106	0.894	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.105	0.895	0.000
C16.6 Greater curvature of stomach, unspecified	0.105	0.895	0.000
C25.7 Other parts of pancreas	0.105	0.895	0.000
C15.8 Overlapping lesion of oesophagus	0.105	0.895	0.000
C15.2 Abdominal part of oesophagus	0.105	0.895	0.000
C15.1 Thoracic part of oesophagus	0.105	0.895	0.000
C15.0 Cervical part of oesophagus	0.105	0.895	0.000
C16.3 Pyloric antrum	0.104	0.896	0.000
C25.0 Head of pancreas	0.102	0.898	0.000
C16.2 Body of stomach	0.101	0.899	0.000
C15.3 Upper third of oesophagus	0.101	0.899	0.000
C25.8 Overlapping lesion of pancreas	0.100	0.900	0.000
C16.8 Overlapping lesion of stomach	0.095	0.905	0.000
C16.4 Pylorus	0.095	0.905	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.094	0.906	0.000
N20.1 Calculus of ureter	0.092	0.908	0.000
C16.1 Fundus of stomach	0.090	0.910	0.000
C25.2 Tail of pancreas	0.085	0.915	0.000
C15.4 Middle third of oesophagus	0.085	0.915	0.000
C26.9 Ill-defined sites within the digestive system	0.084	0.916	0.000
C21 Malignant neoplasm of anus and anal canal	0.083	0.917	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.079	0.921	0.000
C26.0 Intestinal tract, part unspecified	0.078	0.922	0.000
C17 Malignant neoplasm of small intestine	0.076	0.924	0.000
C26.8 Overlapping lesion of digestive system	0.076	0.924	0.000
C26.1 Spleen	0.076	0.924	0.000
C16.5 Lesser curvature of stomach, unspecified	0.074	0.926	0.000
C24.1 Ampulla of Vater	0.072	0.928	0.000
C24.8 Overlapping lesion of biliary tract	0.067	0.932	0.000
C24.9 Biliary tract, unspecified	0.064	0.936	0.000
N20 Calculus of kidney and ureter	0.064	0.936	0.000
C24.0 Extrahepatic bile duct	0.063	0.937	0.000
C17.0 Duodenum	0.061	0.939	0.000
N20.2 Calculus of kidney with calculus of ureter	0.061	0.939	0.000
C22.1 Intrahepatic bile duct carcinoma	0.061	0.939	0.000
C21.0 Anus, unspecified	0.060	0.940	0.000
C21.2 Cloacogenic zone	0.060	0.940	0.000
O26.8 Other specified pregnancy-related conditions	0.057	0.943	0.000
C22.7 Other specified carcinomas of liver	0.057	0.943	0.000
C22.4 Other sarcomas of liver	0.057	0.943	0.000
C22.3 Angiosarcoma of liver	0.057	0.943	0.000
C22.2 Hepatoblastoma	0.057	0.943	0.000
C17.8 Overlapping lesion of small intestine	0.055	0.945	0.000
C17.3 Meckel's diverticulum	0.055	0.945	0.000
C22.0 Liver cell carcinoma	0.055	0.945	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.054	0.945	0.000
C21.1 Anal canal	0.053	0.947	0.000
C17.1 Jejunum	0.053	0.947	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.047	0.953	0.000
C17.9 Small intestine, unspecified	0.046	0.953	0.000
C17.2 Ileum	0.038	0.961	0.000
N20.0 Calculus of kidney	0.037	0.963	0.000
N20.9 Urinary calculus, unspecified	0.035	0.965	0.000
C22.9 Liver, unspecified	0.034	0.966	0.000
C20 Malignant neoplasm of rectum	0.028	0.972	0.000
C18 Malignant neoplasm of colon	0.026	0.974	0.000
N20-N23 Urolithiasis	0.024	0.976	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.024	0.976	0.000
C18.6 Descending colon	0.022	0.978	0.000
C18.1 Appendix	0.021	0.979	0.000
C18.4 Transverse colon	0.021	0.979	0.000
N23 Unspecified renal colic	0.020	0.980	0.000
O26.2 Pregnancy care of habitual aborter	0.019	0.981	0.000
C18.7 Sigmoid colon	0.019	0.981	0.000
C18.8 Overlapping lesion of colon	0.019	0.981	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.018	0.982	0.000
O26.0 Excessive weight gain in pregnancy	0.018	0.982	0.000
O26.5 Maternal hypotension syndrome	0.017	0.982	0.000
O26.4 Herpes gestationis	0.017	0.982	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.017	0.982	0.000
O26.1 Low weight gain in pregnancy	0.017	0.982	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.017	0.983	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.017	0.983	0.000
C18.3 Hepatic flexure	0.016	0.984	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.015	0.985	0.000
I35.9 Aortic valve disorder, unspecified	0.014	0.986	0.000
I35.0 Aortic (valve) stenosis	0.014	0.986	0.000
I35.8 Other aortic valve disorders	0.013	0.987	0.000
I35 Nonrheumatic aortic valve disorders	0.013	0.987	0.000
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.013	0.987	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.013	0.987	0.000
C18.5 Splenic flexure	0.012	0.988	0.000
N21 Calculus of lower urinary tract	0.012	0.988	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.012	0.988	0.000
O26.9 Pregnancy-related condition, unspecified	0.011	0.989	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.011	0.989	0.000
I78.1 Naevus, nonneoplastic	0.000	0.990	0.010
O21 Excessive vomiting in pregnancy	0.010	0.990	0.000
C18.2 Ascending colon	0.010	0.990	0.000
O20 Haemorrhage in early pregnancy	0.009	0.991	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.009	0.991	0.000
O22 Venous complications in pregnancy	0.009	0.991	0.000
O28 Abnormal findings on antenatal screening of mother	0.009	0.991	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.009	0.991	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.009	0.991	0.000
O29 Complications of anaesthesia during pregnancy	0.009	0.991	0.000
O25 Malnutrition in pregnancy	0.009	0.991	0.000
O23 Infections of genito-urinary tract in pregnancy	0.008	0.991	0.000
O21.2 Late vomiting of pregnancy	0.008	0.992	0.000
N21.0 Calculus in bladder	0.008	0.992	0.000
N21.1 Calculus in urethra	0.008	0.992	0.000
O20.8 Other haemorrhage in early pregnancy	0.008	0.992	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.008	0.992	0.000
O21.0 Mild hyperemesis gravidarum	0.007	0.992	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.007	0.992	0.000
O21.8 Other vomiting complicating pregnancy	0.007	0.993	0.000
O21.9 Vomiting of pregnancy, unspecified	0.007	0.993	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.007	0.993	0.000
O22.4 Haemorrhoids in pregnancy	0.007	0.993	0.000
N21.8 Other lower urinary tract calculus	0.007	0.993	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.007	0.993	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.007	0.993	0.000
N13 Obstructive and reflux uropathy	0.007	0.993	0.000
N13.6 Pyonephrosis	0.007	0.993	0.000
O22.9 Venous complication in pregnancy, unspecified	0.006	0.993	0.000
O22.8 Other venous complications in pregnancy	0.006	0.993	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.006	0.993	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.006	0.993	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.006	0.993	0.000
O22.1 Genital varices in pregnancy	0.006	0.993	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.006	0.993	0.000
O20.0 Threatened abortion	0.007	0.993	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.006	0.993	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.006	0.993	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.006	0.993	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.006	0.993	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.006	0.993	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.006	0.993	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.006	0.993	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.007	0.993	0.000
C18.0 Caecum	0.006	0.993	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.006	0.993	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.006	0.993	0.000
O29.6 Failed or difficult intubation during pregnancy	0.006	0.993	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.006	0.993	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.006	0.993	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.006	0.993	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.006	0.993	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.006	0.993	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.006	0.993	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.006	0.994	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.006	0.994	0.000
O23.2 Infections of urethra in pregnancy	0.006	0.994	0.000
O23.1 Infections of bladder in pregnancy	0.006	0.994	0.000
O23.0 Infections of kidney in pregnancy	0.006	0.994	0.000
I78 Diseases of capillaries	0.000	0.994	0.006
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.994	0.006
D55-D59 Haemolytic anaemias	0.006	0.994	0.000
O23.5 Infections of the genital tract in pregnancy	0.006	0.994	0.000
O24 Diabetes mellitus in pregnancy	0.006	0.994	0.000
D68 Other coagulation defects	0.006	0.994	0.000
Z51.8 Other specified medical care	0.006	0.994	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.005	0.995	0.000
D67 Hereditary factor IX deficiency	0.005	0.995	0.000
D35.1 Parathyroid gland	0.005	0.995	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.005	0.995	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.005	0.995	0.000
D68.5 Primary Thrombophilia	0.005	0.995	0.000
I78.8 Other diseases of capillaries	0.000	0.995	0.005
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.005	0.995	0.000
I78.9 Disease of capillaries, unspecified	0.000	0.995	0.005
D69 Purpura and other haemorrhagic conditions	0.005	0.995	0.000
D57 Sickle-cell disorders	0.005	0.995	0.000
D68.0 Von Willebrand's disease	0.005	0.995	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.005	0.995	0.000
D68.2 Hereditary deficiency of other clotting factors	0.005	0.995	0.000
D58 Other hereditary haemolytic anaemias	0.004	0.996	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.004	0.996	0.000
D55 Anaemia due to enzyme disorders	0.004	0.996	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.004	0.996	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.004	0.996	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.004	0.996	0.000
D68.4 Acquired coagulation factor deficiency	0.004	0.996	0.000
D68.1 Hereditary factor XI deficiency	0.004	0.996	0.000
D56 Thalassaemia	0.004	0.996	0.000
D68.6 Other Thrombophilia	0.004	0.996	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.004	0.996	0.000
D69.6 Thrombocytopenia, unspecified	0.004	0.996	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.004	0.996	0.000
D57.1 Sickle-cell anaemia without crisis	0.004	0.996	0.000
D69.0 Allergic purpura	0.004	0.996	0.000
D68.8 Other specified coagulation defects	0.004	0.996	0.000
N13.8 Other obstructive and reflux uropathy	0.004	0.996	0.000
D69.9 Haemorrhagic condition, unspecified	0.004	0.996	0.000
D66 Hereditary factor VIII deficiency	0.004	0.996	0.000
S02.10 Fracture of base of skull (closed)	0.004	0.996	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.004	0.996	0.000
D69.8 Other specified haemorrhagic conditions	0.004	0.996	0.000
D69.2 Other nonthrombocytopenic purpura	0.004	0.996	0.000
D69.1 Qualitative platelet defects	0.004	0.996	0.000
D57.8 Other sickle-cell disorders	0.003	0.996	0.000
D57.3 Sickle-cell trait	0.003	0.996	0.000
D57.2 Double heterozygous sickling disorders	0.003	0.996	0.000
D57.0 Sickle-cell anaemia with crisis	0.003	0.996	0.000
D58.0 Hereditary spherocytosis	0.003	0.996	0.000
I30.9 Acute pericarditis, unspecified	0.004	0.996	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.003	0.996	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.003	0.996	0.000
D58.2 Other haemoglobinopathies	0.003	0.996	0.000
D58.1 Hereditary elliptocytosis	0.003	0.996	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.003	0.997	0.000
D55.8 Other anaemias due to enzyme disorders	0.003	0.997	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.003	0.997	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.003	0.997	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.003	0.997	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.003	0.997	0.000
C18.9 Colon, unspecified	0.003	0.997	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.003	0.997	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.997	0.000
D50-D53 Nutritional anaemias	0.003	0.997	0.000
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
D59 Acquired haemolytic anaemia	0.003	0.997	0.000
D56.9 Thalassaemia, unspecified	0.003	0.997	0.000
D56.8 Other thalassaemias	0.003	0.997	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.003	0.997	0.000
D56.2 Delta-beta thalassaemia	0.003	0.997	0.000
D56.1 Beta thalassaemia	0.003	0.997	0.000
D56.0 Alpha thalassaemia	0.003	0.997	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.997	0.000
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
E85.4 Organ-limited amyloidosis	0.003	0.997	0.000
N13.4 Hydroureter	0.003	0.997	0.000
E85 Amyloidosis	0.003	0.997	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000
Z96.0 Presence of urogenital implants	0.003	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.003	0.997	0.000
D56.3 Thalassaemia trait	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
E85.8 Other amyloidosis	0.003	0.997	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.003	0.997	0.000
O41.0 Oligohydramnios	0.003	0.997	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
D51 Vitamin B12 deficiency anaemia	0.003	0.997	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.997	0.000
I30.1 Infective pericarditis	0.003	0.997	0.000
D59.8 Other acquired haemolytic anaemias	0.002	0.997	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.002	0.997	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.002	0.997	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.002	0.997	0.000
D59.3 Haemolytic-uraemic syndrome	0.002	0.997	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.002	0.997	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.002	0.997	0.000
N13.3 Other and unspecified hydronephrosis	0.003	0.997	0.000
D69.5 Secondary thrombocytopenia	0.002	0.997	0.000
Z90.3 Acquired absence of part of stomach	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.002	0.997	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.002	0.997	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.002	0.997	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.002	0.997	0.000
I30 Acute pericarditis	0.002	0.997	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
G90.2 Horner's syndrome	0.000	0.998	0.002
D53 Other nutritional anaemias	0.002	0.998	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.002	0.998	0.000
Z95.4 Presence of other heart-valve replacement	0.002	0.998	0.000
G71.1 Myotonic disorders	0.002	0.998	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.002	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.002	0.998	0.000
D51.2 Transcobalamin II deficiency	0.002	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.002	0.998	0.000
K83.1 Obstruction of bile duct	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
D52 Folate deficiency anaemia	0.002	0.998	0.000
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.002	0.998	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.002	0.998	0.000
G95.9 Disease of spinal cord, unspecified	0.000	0.998	0.002
I30.8 Other forms of acute pericarditis	0.002	0.998	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.002	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.002	0.998	0.000
D53.8 Other specified nutritional anaemias	0.002	0.998	0.000
D53.2 Scorbutic anaemia	0.002	0.998	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.002	0.998	0.000
D53.0 Protein deficiency anaemia	0.002	0.998	0.000
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
G71 Primary disorders of muscles	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
J06.9 Acute upper respiratory infection, unspecified	0.002	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.002	0.998	0.000
K76.9 Liver disease, unspecified	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
R54 Senility	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
Z71.1 Person with feared complaint in whom no diagnosis is made	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
D52.8 Other folate deficiency anaemias	0.002	0.998	0.000
D52.1 Drug-induced folate deficiency anaemia	0.002	0.998	0.000
D52.0 Dietary folate deficiency anaemia	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
G70 Myasthenia gravis and other myoneural disorders	0.002	0.998	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
G70.9 Myoneural disorder, unspecified	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
D53.9 Nutritional anaemia, unspecified	0.001	0.998	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.002	0.998	0.000
G71.8 Other primary disorders of muscles	0.002	0.998	0.000
G71.2 Congenital myopathies	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.998	0.002
Z11.2 Special screening examination for other bacterial diseases	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
A04.5 Campylobacter enteritis	0.000	0.998	0.002
G71.0 Muscular dystrophy	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.001	0.998	0.000
S02.11 Fracture of base of skull (open)	0.001	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.998	0.002
I82.9 Embolism and thrombosis of unspecified vein	0.000	0.998	0.002
N11.1 Chronic obstructive pyelonephritis	0.001	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.001	0.998	0.000
G70.8 Other specified myoneural disorders	0.001	0.998	0.000
G70.2 Congenital and developmental myasthenia	0.001	0.998	0.000
G70.1 Toxic myoneural disorders	0.001	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.001	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.001	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.001	0.998	0.000
N14.0 Analgesic nephropathy	0.001	0.998	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
Z43.1 Attention to gastrostomy	0.002	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.000	0.998	0.001
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.998	0.002
M43.0 Spondylolysis	0.001	0.998	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.998	0.000
D60.8 Other acquired pure red cell aplasias	0.001	0.998	0.000
D60.1 Transient acquired pure red cell aplasia	0.001	0.998	0.000
D60.0 Chronic acquired pure red cell aplasia	0.001	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.001	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.001
G72.0 Drug-induced myopathy	0.001	0.999	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.001	0.999	0.000
O14.1 Severe preeclampsia	0.001	0.999	0.000
Z11.5 Special screening examination for other viral diseases	0.001	0.999	0.000
E88 Other metabolic disorders	0.001	0.999	0.000
G70-G73 Diseases of myoneural junction and muscle	0.001	0.999	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.999	0.001
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.001	0.999	0.000
M43.09 Spondylolysis (Site unspecified)	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.001	0.999	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.001	0.999	0.000
E88.3 Tumour lysis syndrome	0.001	0.999	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.001	0.999	0.000
O12.0 Gestational oedema	0.001	0.999	0.000
Z12.4 Special screening examination for neoplasm of cervix	0.001	0.999	0.000
H80.9 Otosclerosis, unspecified	0.001	0.999	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.001	0.999	0.000
G72 Other myopathies	0.001	0.999	0.000
I08 Multiple valve diseases	0.001	0.999	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.001	0.999	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.001	0.999	0.000
C43.5 Malignant melanoma of trunk	0.000	0.999	0.001
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.001	0.999	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.001	0.999	0.000
N15.0 Balkan nephropathy	0.001	0.999	0.000
O41 Other disorders of amniotic fluid and membranes	0.001	0.999	0.000
M24.07 Loose body in joint (Ankle and foot)	0.001	0.999	0.000
T20.0 Burn of unspecified degree of head and neck	0.001	0.999	0.000
G95 Other diseases of spinal cord	0.000	0.999	0.001
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M43.07 Spondylolysis (Lumbosacral region)	0.001	0.999	0.000
M43.05 Spondylolysis (Thoracolumbar region)	0.001	0.999	0.000
M43.04 Spondylolysis (Thoracic region)	0.001	0.999	0.000
M43.03 Spondylolysis (Cervicothoracic region)	0.001	0.999	0.000
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.001	0.999	0.000
M43.00 Spondylolysis (Multiple sites in spine)	0.001	0.999	0.000
G30.8 Other Alzheimer's disease	0.000	0.999	0.001
G30.1 Alzheimer's disease with late onset	0.000	0.999	0.001
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.001	0.999	0.000
R44.1 Visual hallucinations	0.001	0.999	0.000
M43.02 Spondylolysis (Cervical region)	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.999	0.001
E88.9 Metabolic disorder, unspecified	0.001	0.999	0.000
N76.4 Abscess of vulva	0.001	0.999	0.000
O14.0 Moderate preeclampsia	0.001	0.999	0.000
Q38.7 Pharyngeal pouch	0.000	0.999	0.001
Q51.2 Other doubling of uterus	0.001	0.999	0.000
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.999	0.001
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.001	0.999	0.000
E88.2 Lipomatosis, not elsewhere classified	0.001	0.999	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.999	0.001
L27.0 Generalised skin eruption due to drugs and medicaments	0.001	0.999	0.000
N10 Acute tubulo-interstitial nephritis	0.001	0.999	0.000
M70.46 Prepatellar bursitis-Lower Leg	0.000	0.999	0.001
E88.8 Other specified metabolic disorders	0.001	0.999	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.001	0.999	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.999	0.001
Z11.1 Special screening examination for respiratory tuberculosis	0.001	0.999	0.000
E89.3 Postprocedural hypopituitarism	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations