TreeWAS – Variant ID: rs3909130

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
L40 Psoriasis	1.000	0.000	0.000
E00-E07 Disorders of thyroid gland	0.000	0.000	1.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.002	0.998
E10.9 Without complications	0.000	0.003	0.997
L40.0 Psoriasis vulgaris	0.997	0.003	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.004	0.996
E10-E14 Diabetes mellitus	0.000	0.017	0.983
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.018	0.982
E10.4 With neurological complications	0.000	0.043	0.957
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.060	0.940
M07.39 Other psoriatic arthropathies (Site unspecified)	0.937	0.063	0.000
M07.3 Other psoriatic arthropathies	0.937	0.063	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.932	0.068	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.090	0.910
E10.3 With ophthalmic complications	0.000	0.098	0.902
L40.8 Other psoriasis	0.891	0.109	0.000
E10.5 With peripheral circulatory complications	0.000	0.110	0.890
E16.2 Hypoglycaemia, unspecified	0.000	0.110	0.890
E07 Other disorders of thyroid	0.000	0.117	0.883
E10.1 With ketoacidosis	0.000	0.129	0.871
L40.1 Generalised pustular psoriasis	0.854	0.146	0.000
E07.9 Disorder of thyroid, unspecified	0.000	0.165	0.835
E10.6 With other specified complications	0.000	0.168	0.832
M07.34 Other psoriatic arthropathies (Hand)	0.823	0.177	0.000
E10.2 With renal complications	0.000	0.187	0.812
E10.0 With coma	0.000	0.190	0.810
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.199	0.801
M07.36 Other psoriatic arthropathies (Lower leg)	0.799	0.201	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.778	0.222	0.000
E06 Thyroiditis	0.000	0.232	0.768
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.247	0.753
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.267	0.733
E50-E64 Other nutritional deficiencies	0.000	0.274	0.726
E05.8 Other thyrotoxicosis	0.000	0.283	0.717
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.717
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E03.1 Congenital hypothyroidism without goitre	0.000	0.283	0.717
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.284	0.716
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.288	0.712
E12 Malnutrition-related diabetes mellitus	0.000	0.295	0.704
E15 Nondiabetic hypoglycaemic coma	0.000	0.326	0.674
M07.38 Other psoriatic arthropathies (Other)	0.671	0.328	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.671	0.328	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.671	0.328	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.671	0.328	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.671	0.328	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.347	0.652
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.347	0.652
E16.4 Abnormal secretion of gastrin	0.000	0.347	0.652
E16.3 Increased secretion of glucagon	0.000	0.347	0.652
E07.1 Dyshormogenetic goitre	0.000	0.367	0.633
E07.0 Hypersecretion of calcitonin	0.000	0.367	0.633
E03.8 Other specified hypothyroidism	0.000	0.398	0.602
E06.3 Autoimmune thyroiditis	0.000	0.403	0.597
E55 Vitamin D deficiency	0.000	0.427	0.573
E16.1 Other hypoglycaemia	0.000	0.440	0.559
E13 Other specified diabetes mellitus	0.000	0.441	0.558
E06.9 Thyroiditis, unspecified	0.000	0.443	0.557
E10.8 With unspecified complications	0.000	0.448	0.551
E06.5 Other chronic thyroiditis	0.000	0.449	0.551
E06.4 Drug-induced thyroiditis	0.000	0.449	0.551
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.449	0.551
E06.1 Subacute thyroiditis	0.000	0.449	0.551
E06.0 Acute thyroiditis	0.000	0.449	0.551
K90 Intestinal malabsorption	0.000	0.478	0.522
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.479	0.520
E63 Other nutritional deficiencies	0.000	0.479	0.520
E56 Other vitamin deficiencies	0.000	0.479	0.520
E51 Thiamine deficiency	0.000	0.479	0.520
E50 Vitamin A deficiency	0.000	0.479	0.520
E60 Dietary zinc deficiency	0.000	0.479	0.520
E59 Dietary selenium deficiency	0.000	0.479	0.520
E58 Dietary calcium deficiency	0.000	0.479	0.520
E54 Ascorbic acid deficiency	0.000	0.479	0.520
E52 Niacin deficiency [pellagra]	0.000	0.479	0.520
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E65-E68 Obesity and other hyperalimentation	0.000	0.488	0.512
E12.9 Without complications	0.000	0.495	0.505
E12.8 With unspecified complications	0.000	0.495	0.505
E12.7 With multiple complications	0.000	0.495	0.505
E12.6 With other specified complications	0.000	0.495	0.505
E12.5 With peripheral circulatory complications	0.000	0.495	0.505
E12.4 With neurological complications	0.000	0.495	0.505
E12.3 With ophthalmic complications	0.000	0.495	0.505
E12.2 With renal complications	0.000	0.495	0.505
E12.1 With ketoacidosis	0.000	0.495	0.505
E12.0 With coma	0.000	0.495	0.505
E61 Deficiency of other nutrient elements	0.000	0.495	0.505
E53 Deficiency of other B group vitamins	0.000	0.504	0.496
E40-E46 Malnutrition	0.001	0.511	0.488
E14 Unspecified diabetes mellitus	0.000	0.533	0.467
E55.9 Vitamin D deficiency, unspecified	0.000	0.537	0.463
E04 Other non-toxic goitre	0.000	0.551	0.449
E07.8 Other specified disorders of thyroid	0.000	0.554	0.446
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.562	0.438
K90.9 Intestinal malabsorption, unspecified	0.000	0.587	0.413
E14.3 With ophthalmic complications	0.000	0.588	0.412
E55.0 Rickets, active	0.000	0.589	0.411
M07 Psoriatic and enteropathic arthropathies	0.409	0.590	0.000
E13.8 With unspecified complications	0.000	0.599	0.400
E13.7 With multiple complications	0.000	0.599	0.400
E13.6 With other specified complications	0.000	0.599	0.400
E13.5 With peripheral circulatory complications	0.000	0.599	0.400
E13.4 With neurological complications	0.000	0.599	0.400
E13.3 With ophthalmic complications	0.000	0.599	0.400
E13.2 With renal complications	0.000	0.599	0.400
E13.1 With ketoacidosis	0.000	0.599	0.400
E13.0 With coma	0.000	0.599	0.400
E53.9 Vitamin B deficiency, unspecified	0.000	0.622	0.378
K90.3 Pancreatic steatorrhoea	0.000	0.626	0.374
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.626	0.374
K90.1 Tropical sprue	0.000	0.626	0.374
E50.9 Vitamin A deficiency, unspecified	0.000	0.627	0.373
E50.8 Other manifestations of vitamin A deficiency	0.000	0.627	0.373
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.627	0.373
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.627	0.373
E50.5 Vitamin A deficiency with night blindness	0.000	0.627	0.373
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.627	0.373
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.627	0.373
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.627	0.373
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.627	0.373
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.627	0.373
E51.9 Thiamine deficiency, unspecified	0.000	0.627	0.373
E51.8 Other manifestations of thiamine deficiency	0.000	0.627	0.373
E51.2 Wernicke's encephalopathy	0.000	0.627	0.373
E51.1 Beriberi	0.000	0.627	0.373
E56.9 Vitamin deficiency, unspecified	0.000	0.627	0.373
E56.8 Deficiency of other vitamins	0.000	0.627	0.373
E56.1 Deficiency of vitamin K	0.000	0.627	0.373
E56.0 Deficiency of vitamin E	0.000	0.627	0.373
E63.9 Nutritional deficiency, unspecified	0.000	0.627	0.373
E63.8 Other specified nutritional deficiencies	0.000	0.627	0.373
E63.1 Imbalance of constituents of food intake	0.000	0.627	0.373
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.627	0.373
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.627	0.373
E64.8 Sequelae of other nutritional deficiencies	0.000	0.627	0.373
E64.3 Sequelae of rickets	0.000	0.627	0.373
E64.2 Sequelae of vitamin C deficiency	0.000	0.627	0.373
E64.1 Sequelae of vitamin A deficiency	0.000	0.627	0.373
E64.0 Sequelae of protein-energy malnutrition	0.000	0.627	0.373
E61.2 Magnesium deficiency	0.000	0.631	0.369
E67 Other hyperalimentation	0.000	0.633	0.367
E68 Sequelae of hyperalimentation	0.000	0.633	0.367
E61.9 Deficiency of nutrient element, unspecified	0.000	0.638	0.362
E61.8 Deficiency of other specified nutrient elements	0.000	0.638	0.362
E61.7 Deficiency of multiple nutrient elements	0.000	0.638	0.362
E61.6 Vanadium deficiency	0.000	0.638	0.362
E61.5 Molybdenum deficiency	0.000	0.638	0.362
E61.4 Chromium deficiency	0.000	0.638	0.362
E61.3 Manganese deficiency	0.000	0.638	0.362
E61.0 Copper deficiency	0.000	0.638	0.362
E53.1 Pyridoxine deficiency	0.000	0.644	0.356
E53.0 Riboflavin deficiency	0.000	0.644	0.356
E04.9 Non-toxic goitre, unspecified	0.000	0.647	0.353
E44 Protein-energy malnutrition of moderate and mild degree	0.001	0.649	0.350
E45 Retarded development following protein-energy malnutrition	0.001	0.649	0.350
E43 Unspecified severe protein-energy malnutrition	0.001	0.649	0.350
E42 Marasmic kwashiorkor	0.001	0.649	0.350
E41 Nutritional marasmus	0.001	0.649	0.350
E40 Kwashiorkor	0.001	0.649	0.350
E61.1 Iron deficiency	0.000	0.661	0.339
E14.7 With multiple complications	0.000	0.665	0.335
E14.6 With other specified complications	0.000	0.665	0.335
E14.2 Withrenal complications	0.000	0.665	0.335
E14.0 With coma	0.000	0.665	0.335
E14.1 With ketoacidosis	0.000	0.671	0.329
E04.8 Other specified non-toxic goitre	0.000	0.678	0.322
E14.8 With unspecified complications	0.000	0.680	0.320
E14.5 With peripheral circulatory complications	0.000	0.698	0.302
E53.8 Deficiency of other specified B group vitamins	0.000	0.699	0.301
E66 Obesity	0.000	0.705	0.295
M07.6 Other enteropathic arthropathies	0.294	0.706	0.000
M07.5 Arthropathy in ulcerative colitis	0.294	0.706	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.294	0.706	0.000
M07.2 Psoriatic spondylitis	0.294	0.706	0.000
M07.1 Arthritis mutilans	0.294	0.706	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.294	0.706	0.000
E65 Localised adiposity	0.000	0.713	0.287
E66.8 Other obesity	0.000	0.726	0.274
E04.0 Non-toxic diffuse goitre	0.000	0.726	0.274
E14.4 With neurological complications	0.000	0.729	0.270
E67.8 Other specified hyperalimentation	0.000	0.736	0.263
E67.3 Hypervitaminosis D	0.000	0.736	0.263
E67.2 Megavitamin-B6 syndrome	0.000	0.736	0.263
E67.1 Hypercarotenaemia	0.000	0.736	0.263
E67.0 Hypervitaminosis A	0.000	0.736	0.263
E13.9 Without complications	0.001	0.745	0.254
K90.8 Other intestinal malabsorption	0.001	0.745	0.254
E04.2 Non-toxic multinodular goitre	0.000	0.745	0.255
E44.1 Mild protein-energy malnutrition	0.001	0.748	0.251
E44.0 Moderate protein-energy malnutrition	0.001	0.748	0.251
E20-E35 Disorders of other endocrine glands	0.000	0.768	0.232
L40-L45 Papulosquamous disorders	0.225	0.775	0.000
E66.1 Drug-induced obesity	0.000	0.788	0.212
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.211	0.789	0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.211	0.789	0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.211	0.789	0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.211	0.789	0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.211	0.789	0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.211	0.789	0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.211	0.789	0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.211	0.789	0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.211	0.789	0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.211	0.789	0.000
M07.19 Arthritis mutilans (Site unspecified)	0.211	0.789	0.000
M07.18 Arthritis mutilans (Other)	0.211	0.789	0.000
M07.17 Arthritis mutilans (Ankle and foot)	0.211	0.789	0.000
M07.16 Arthritis mutilans (Lower leg)	0.211	0.789	0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.211	0.789	0.000
M07.14 Arthritis mutilans (Hand)	0.211	0.789	0.000
M07.13 Arthritis mutilans (Forearm)	0.211	0.789	0.000
M07.12 Arthritis mutilans (Upper arm)	0.211	0.789	0.000
M07.11 Arthritis mutilans (Shoulder region)	0.211	0.789	0.000
M07.10 Arthritis mutilans (Multiple sites)	0.211	0.789	0.000
M07.29 Psoriatic spondylitis (Site unspecified)	0.211	0.789	0.000
M07.28 Psoriatic spondylitis (Other)	0.211	0.789	0.000
M07.27 Psoriatic spondylitis (Ankle and foot)	0.211	0.789	0.000
M07.26 Psoriatic spondylitis (Lower leg)	0.211	0.789	0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.211	0.789	0.000
M07.24 Psoriatic spondylitis (Hand)	0.211	0.789	0.000
M07.23 Psoriatic spondylitis (Forearm)	0.211	0.789	0.000
M07.22 Psoriatic spondylitis (Upper arm)	0.211	0.789	0.000
M07.21 Psoriatic spondylitis (Shoulder region)	0.211	0.789	0.000
M07.20 Psoriatic spondylitis (Multiple sites)	0.211	0.789	0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.211	0.789	0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.211	0.789	0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.211	0.789	0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.211	0.789	0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.211	0.789	0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.211	0.789	0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.211	0.789	0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.211	0.789	0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.211	0.789	0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.211	0.789	0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.211	0.789	0.000
M07.58 Arthropathy in ulcerative colitis (Other)	0.211	0.789	0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.211	0.789	0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.211	0.789	0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.211	0.789	0.000
M07.54 Arthropathy in ulcerative colitis (Hand)	0.211	0.789	0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.211	0.789	0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.211	0.789	0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.211	0.789	0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.211	0.789	0.000
M07.69 Other enteropathic arthropathies (Site unspecified)	0.211	0.789	0.000
M07.68 Other enteropathic arthropathies (Other)	0.211	0.789	0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.211	0.789	0.000
M07.66 Other enteropathic arthropathies (Lower leg)	0.211	0.789	0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.211	0.789	0.000
M07.64 Other enteropathic arthropathies (Hand)	0.211	0.789	0.000
M07.63 Other enteropathic arthropathies (Forearm)	0.211	0.789	0.000
M07.62 Other enteropathic arthropathies (Upper arm)	0.211	0.789	0.000
M07.61 Other enteropathic arthropathies (Shoulder region)	0.211	0.789	0.000
M07.60 Other enteropathic arthropathies (Multiple sites)	0.211	0.789	0.000
E27 Other disorders of adrenal gland	0.000	0.792	0.208
E27.1 Primary adrenocortical insufficiency	0.000	0.794	0.206
E04.1 Non-toxic single thyroid nodule	0.000	0.801	0.199
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.817	0.183
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.000	0.824	0.176
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.833	0.166
E32 Diseases of thymus	0.000	0.833	0.166
E31 Polyglandular dysfunction	0.000	0.833	0.166
E30 Disorders of puberty, not elsewhere classified	0.000	0.833	0.166
E25 Adrenogenital disorders	0.000	0.833	0.166
E34 Other endocrine disorders	0.000	0.836	0.164
L44 Other papulosquamous disorders	0.161	0.838	0.000
L41 Parapsoriasis	0.161	0.838	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.161	0.838	0.000
E29 Testicular dysfunction	0.000	0.842	0.158
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.157	0.843	0.000
E20 Hypoparathyroidism	0.000	0.843	0.157
E66.0 Obesity due to excess calories	0.000	0.843	0.156
L42 Pityriasis rosea	0.156	0.843	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.845	0.155
T36-T50 Poisoning by drugs, medicaments and biological substances	0.155	0.845	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.153	0.847	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.151	0.849	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.850	0.149
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.850	0.149
E27.0 Other adrenocortical overactivity	0.000	0.850	0.149
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.144	0.856	0.000
E22 Hyperfunction of pituitary gland	0.000	0.856	0.144
T43.2 Other and unspecified antidepressants	0.144	0.856	0.000
E26 Hyperaldosteronism	0.000	0.856	0.143
E24 Cushing's syndrome	0.000	0.858	0.142
E27.2 Addisonian crisis	0.000	0.860	0.140
E28 Ovarian dysfunction	0.000	0.863	0.137
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.135	0.864	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.865	0.133
T43.0 Tricyclic and tetracyclic antidepressants	0.134	0.866	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.133	0.867	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.132	0.868	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.871	0.129
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.128	0.872	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.127	0.873	0.000
T43.6 Psychostimulants with abuse potential	0.124	0.876	0.000
E34.0 Carcinoid syndrome	0.000	0.877	0.122
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.122	0.878	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.120	0.880	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.880	0.119
E25.8 Other adrenogenital disorders	0.000	0.880	0.119
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.880	0.119
E30.9 Disorder of puberty, unspecified	0.000	0.880	0.119
E30.8 Other disorders of puberty	0.000	0.880	0.119
E30.1 Precocious puberty	0.000	0.880	0.119
E30.0 Delayed puberty	0.000	0.880	0.119
E31.9 Polyglandular dysfunction, unspecified	0.000	0.880	0.119
E31.8 Other polyglandular dysfunction	0.000	0.880	0.119
E31.1 Polyglandular hyperfunction	0.000	0.880	0.119
E31.0 Autoimmune polyglandular failure	0.000	0.880	0.119
E32.9 Disease of thymus, unspecified	0.000	0.880	0.119
E32.8 Other diseases of thymus	0.000	0.880	0.119
E32.1 Abscess of thymus	0.000	0.880	0.119
E32.0 Persistent hyperplasia of thymus	0.000	0.880	0.119
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.880	0.119
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.880	0.119
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.880	0.119
T47.1 Other antacids and anti-gastric-secretion drugs	0.118	0.882	0.000
E34.5 Androgen resistance syndrome	0.000	0.882	0.117
E34.4 Constitutional tall stature	0.000	0.882	0.117
E34.3 Short stature, not elsewhere classified	0.000	0.882	0.117
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.882	0.117
E34.1 Other hypersecretion of intestinal hormones	0.000	0.882	0.117
T50.9 Other and unspecified drugs, medicaments and biological substances	0.117	0.883	0.000
T36 Poisoning by systemic antibiotics	0.117	0.883	0.000
L41.9 Parapsoriasis, unspecified	0.116	0.884	0.000
L41.8 Other parapsoriasis	0.116	0.884	0.000
L41.5 Retiform parapsoriasis	0.116	0.884	0.000
L41.4 Large plaque parapsoriasis	0.116	0.884	0.000
L41.3 Small plaque parapsoriasis	0.116	0.884	0.000
L41.2 Lymphomatoid papulosis	0.116	0.884	0.000
L41.1 Pityriasis lichenoides chronica	0.116	0.884	0.000
L41.0 Pityriasis lichenoides et varioliformis acuta	0.116	0.884	0.000
L44.9 Papulosquamous disorder, unspecified	0.116	0.884	0.000
L44.8 Other specified papulosquamous disorders	0.116	0.884	0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.116	0.884	0.000
L44.3 Lichen ruber moniliformis	0.116	0.884	0.000
L44.2 Lichen striatus	0.116	0.884	0.000
L44.1 Lichen nitidus	0.116	0.884	0.000
L44.0 Pityriasis rubra pilaris	0.116	0.884	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.116	0.884	0.000
E22.1 Hyperprolactinaemia	0.000	0.886	0.114
E29.9 Testicular dysfunction, unspecified	0.000	0.887	0.113
E29.8 Other testicular dysfunction	0.000	0.887	0.113
E29.0 Testicular hyperfunction	0.000	0.887	0.113
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.113	0.887	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.113	0.887	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.113	0.887	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.113	0.887	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.113	0.887	0.000
T44.0 Anticholinesterase agents	0.113	0.887	0.000
E20.8 Other hypoparathyroidism	0.000	0.887	0.113
E20.1 Pseudohypoparathyroidism	0.000	0.887	0.113
E20.0 Idiopathic hypoparathyroidism	0.000	0.887	0.113
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.112	0.888	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.111	0.889	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.111	0.889	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.111	0.889	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.111	0.889	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.111	0.889	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.111	0.889	0.000
T43.9 Psychotropic drug, unspecified	0.110	0.890	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.110	0.890	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.110	0.890	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.106	0.894	0.000
T47.4 Other laxatives	0.106	0.894	0.000
E29.1 Testicular hypofunction	0.000	0.896	0.104
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.896	0.103
E22.8 Other hyperfunction of pituitary gland	0.000	0.896	0.103
E20.9 Hypoparathyroidism, unspecified	0.000	0.897	0.103
E24.2 Drug-induced Cushing's syndrome	0.000	0.897	0.103
E26.9 Hyperaldosteronism, unspecified	0.000	0.897	0.103
E26.8 Other hyperaldosteronism	0.000	0.897	0.103
E26.1 Secondary hyperaldosteronism	0.000	0.897	0.103
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.897	0.103
E24.8 Other Cushing's syndrome	0.000	0.898	0.102
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.898	0.102
E24.3 Ectopic ACTH syndrome	0.000	0.898	0.102
E24.1 Nelson's syndrome	0.000	0.898	0.102
E28.9 Ovarian dysfunction, unspecified	0.000	0.901	0.098
E28.8 Other ovarian dysfunction	0.000	0.901	0.098
E28.1 Androgen excess	0.000	0.901	0.098
E28.0 Oestrogen excess	0.000	0.901	0.098
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.097	0.903	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.097	0.903	0.000
T47.7 Emetics	0.097	0.903	0.000
T47.6 Antidiarrhoeal drugs	0.097	0.903	0.000
T47.5 Digestants	0.097	0.903	0.000
T47.3 Saline and osmotic laxatives	0.097	0.903	0.000
T47.2 Stimulant laxatives	0.097	0.903	0.000
T47.0 Histamine H(2)-receptor antagonists	0.097	0.903	0.000
E22.0 Acromegaly and pituitary gigantism	0.000	0.904	0.096
T50.8 Diagnostic agents	0.095	0.904	0.000
T50.7 Analeptics and opioid receptor antagonists	0.095	0.904	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.095	0.904	0.000
T50.5 Appetite depressants	0.095	0.904	0.000
T50.4 Drugs affecting uric acid metabolism	0.095	0.904	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.095	0.904	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.095	0.904	0.000
T50.1 Loop [high-ceiling] diuretics	0.095	0.904	0.000
T50.0 Mineralocorticoids and their antagonists	0.095	0.904	0.000
E28.3 Primary ovarian failure	0.000	0.905	0.095
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.095	0.905	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.093	0.907	0.000
E27.9 Disorder of adrenal gland, unspecified	0.001	0.907	0.092
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.907	0.092
E24.0 Pituitary-dependent Cushing's disease	0.000	0.908	0.092
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.092	0.908	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.092	0.908	0.000
T42.3 Barbiturates	0.092	0.908	0.000
T42.2 Succinimides and oxazolidinediones	0.092	0.908	0.000
T45.0 Antiallergic and antiemetic drugs	0.091	0.908	0.000
T38.1 Thyroid hormones and substitutes	0.091	0.909	0.000
E34.8 Other specified endocrine disorders	0.000	0.909	0.091
E23 Hypofunction and other disorders of pituitary gland	0.000	0.909	0.090
T36.0 Penicillins	0.090	0.910	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.090	0.910	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.910	0.090
T42.0 Hydantoin derivatives	0.089	0.911	0.000
T38.9 Other and unspecified hormone antagonists	0.087	0.912	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.087	0.912	0.000
T38.7 Androgens and anabolic congeners	0.087	0.912	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.087	0.912	0.000
T38.5 Other oestrogens and progestogens	0.087	0.912	0.000
T38.4 Oral contraceptives	0.087	0.912	0.000
T38.2 Antithyroid drugs	0.087	0.912	0.000
T38.0 Glucocorticoids and synthetic analogues	0.087	0.912	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.087	0.912	0.000
T42.1 Iminostilbenes	0.087	0.913	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.087	0.913	0.000
T36.9 Systemic antibiotic, unspecified	0.084	0.916	0.000
T36.8 Other systemic antibiotics	0.084	0.916	0.000
T36.7 Antifungal antibiotics, systemically used	0.084	0.916	0.000
T36.6 Rifamycins	0.084	0.916	0.000
T36.5 Aminoglycosides	0.084	0.916	0.000
T36.4 Tetracyclines	0.084	0.916	0.000
T36.3 Macrolides	0.084	0.916	0.000
T36.2 Chloramphenicol group	0.084	0.916	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.084	0.916	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.083	0.917	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.083	0.917	0.000
T46.7 Peripheral vasodilators	0.083	0.917	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.083	0.917	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.083	0.917	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.083	0.917	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.082	0.917	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.080	0.919	0.000
T45.8 Other primarily systemic and haematological agents	0.080	0.919	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.080	0.919	0.000
T45.6 Fibrinolysis-affecting drugs	0.080	0.919	0.000
T45.4 Iron and its compounds	0.080	0.919	0.000
T45.3 Enzymes, not elsewhere classified	0.080	0.919	0.000
T45.2 Vitamins, not elsewhere classified	0.080	0.919	0.000
E26.0 Primary hyperaldosteronism	0.000	0.920	0.080
L43 Lichen planus	0.079	0.920	0.001
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.080	0.920	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.080	0.920	0.000
T37.5 Antiviral drugs	0.080	0.920	0.000
T37.4 Anthelminthics	0.080	0.920	0.000
T37.3 Other antiprotozoal drugs	0.080	0.920	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.080	0.920	0.000
T37.1 Antimycobacterial drugs	0.080	0.920	0.000
T37.0 Sulphonamides	0.080	0.920	0.000
T41.5 Therapeutic gases	0.080	0.920	0.000
T41.4 Anaesthetic, unspecified	0.080	0.920	0.000
T41.3 Local anaesthetics	0.080	0.920	0.000
T41.2 Other and unspecified general anaesthetics	0.080	0.920	0.000
T41.1 Intravenous anaesthetics	0.080	0.920	0.000
T41.0 Inhaled anaesthetics	0.080	0.920	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.080	0.920	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.080	0.920	0.000
T48.5 Anti-common-cold drugs	0.080	0.920	0.000
T48.4 Expectorants	0.080	0.920	0.000
T48.3 Antitussives	0.080	0.920	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.080	0.920	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations