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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3916232
log Bayes Factor = 61.1574
Chromosome 6   position 30,823,366  (GRCh37) Explore rs3916232 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
L40 Psoriasis
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.005 0.995
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.005 0.995
E10-E14 Diabetes mellitus
0.000 0.006 0.994
L40.0 Psoriasis vulgaris
0.992 0.008 0.000
E10.4 With neurological complications
0.000 0.030 0.970
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.068 0.932
E10.5 With peripheral circulatory complications
0.000 0.093 0.907
E50-E64 Other nutritional deficiencies
0.000 0.109 0.891
E16 Other disorders of pancreatic internal secretion
0.000 0.113 0.887
E10.3 With ophthalmic complications
0.000 0.122 0.878
E16.2 Hypoglycaemia, unspecified
0.000 0.146 0.854
L40.8 Other psoriasis
0.848 0.152 0.000
E10.1 With ketoacidosis
0.000 0.155 0.845
L40.1 Generalised pustular psoriasis
0.836 0.164 0.000
E10.2 With renal complications
0.000 0.166 0.834
E07 Other disorders of thyroid
0.000 0.175 0.825
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.188 0.812
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.808 0.192 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.806 0.194 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.796 0.204 0.000
T43.2 Other and unspecified antidepressants
0.796 0.204 0.000
E55 Vitamin D deficiency
0.000 0.205 0.795
E06 Thyroiditis
0.000 0.210 0.790
E07.9 Disorder of thyroid, unspecified
0.000 0.248 0.752
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.750 0.250 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.740 0.260 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.734 0.266 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.274 0.726
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.720 0.280 0.000
E05.8 Other thyrotoxicosis
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.717 0.283 0.000
L40.3 Pustulosis palmaris et plantaris
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
T43.4 Butyrophenone and thioxanthene neuroleptics
0.717 0.283 0.000
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.287 0.713
E53 Deficiency of other B group vitamins
0.000 0.288 0.712
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.293 0.707
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.304 0.696
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.693 0.307 0.000
E10.8 With unspecified complications
0.000 0.322 0.678
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.678 0.322 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.670 0.330 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.332 0.668
T43.6 Psychostimulants with abuse potential
0.665 0.335 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.655 0.345 0.000
E13 Other specified diabetes mellitus
0.000 0.349 0.651
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.361 0.639
E63 Other nutritional deficiencies
0.000 0.361 0.639
E56 Other vitamin deficiencies
0.000 0.361 0.639
E51 Thiamine deficiency
0.000 0.361 0.639
E50 Vitamin A deficiency
0.000 0.361 0.639
E60 Dietary zinc deficiency
0.000 0.361 0.639
E59 Dietary selenium deficiency
0.000 0.361 0.639
E58 Dietary calcium deficiency
0.000 0.361 0.639
E54 Ascorbic acid deficiency
0.000 0.361 0.639
E52 Niacin deficiency [pellagra]
0.000 0.361 0.639
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.364 0.636
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.364 0.636
E16.4 Abnormal secretion of gastrin
0.000 0.364 0.636
E16.3 Increased secretion of glucagon
0.000 0.364 0.636
E06.3 Autoimmune thyroiditis
0.000 0.367 0.633
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.633 0.367 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.628 0.372 0.000
E03.8 Other specified hypothyroidism
0.000 0.379 0.620
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.619 0.381 0.000
E61 Deficiency of other nutrient elements
0.000 0.382 0.618
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.617 0.383 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.392 0.608
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.606 0.394 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.606 0.394 0.000
E07.1 Dyshormogenetic goitre
0.000 0.408 0.592
E07.0 Hypersecretion of calcitonin
0.000 0.408 0.592
E53.8 Deficiency of other specified B group vitamins
0.000 0.416 0.584
T47.1 Other antacids and anti-gastric-secretion drugs
0.581 0.419 0.000
T43.9 Psychotropic drug, unspecified
0.579 0.421 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.579 0.421 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.579 0.421 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.578 0.422 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.578 0.422 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.578 0.422 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.578 0.422 0.000
T45.0 Antiallergic and antiemetic drugs
0.576 0.424 0.000
E06.9 Thyroiditis, unspecified
0.000 0.425 0.575
T43.3 Phenothiazine antipsychotics and neuroleptics
0.572 0.428 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.571 0.429 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.571 0.429 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.571 0.429 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.571 0.429 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.571 0.429 0.000
T44.0 Anticholinesterase agents
0.571 0.429 0.000
E55.0 Rickets, active
0.000 0.430 0.570
E06.5 Other chronic thyroiditis
0.000 0.433 0.566
E06.4 Drug-induced thyroiditis
0.000 0.433 0.566
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.433 0.566
E06.1 Subacute thyroiditis
0.000 0.433 0.566
E06.0 Acute thyroiditis
0.000 0.433 0.566
E16.1 Other hypoglycaemia
0.000 0.438 0.561
T36 Poisoning by systemic antibiotics
0.558 0.441 0.000
T47.4 Other laxatives
0.550 0.449 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.546 0.454 0.000
T39.0 Salicylates
0.528 0.472 0.000
E40-E46 Malnutrition
0.001 0.476 0.523
T39.1 4-Aminophenol derivatives
0.517 0.483 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.516 0.483 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.516 0.483 0.000
T42.3 Barbiturates
0.516 0.483 0.000
T42.2 Succinimides and oxazolidinediones
0.516 0.483 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.515 0.485 0.000
M07.3 Other psoriatic arthropathies
0.515 0.485 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.489 0.511
E12.8 With unspecified complications
0.000 0.489 0.511
E12.7 With multiple complications
0.000 0.489 0.511
E12.6 With other specified complications
0.000 0.489 0.511
E12.5 With peripheral circulatory complications
0.000 0.489 0.511
E12.4 With neurological complications
0.000 0.489 0.511
E12.3 With ophthalmic complications
0.000 0.489 0.511
E12.2 With renal complications
0.000 0.489 0.511
E12.1 With ketoacidosis
0.000 0.489 0.511
E12.0 With coma
0.000 0.489 0.511
E53.9 Vitamin B deficiency, unspecified
0.000 0.489 0.511
E53.1 Pyridoxine deficiency
0.000 0.489 0.511
E53.0 Riboflavin deficiency
0.000 0.489 0.511
M07.39 Other psoriatic arthropathies (Site unspecified)
0.507 0.493 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.505 0.495 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.497 0.503 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.497 0.503 0.000
T47.7 Emetics
0.497 0.503 0.000
T47.6 Antidiarrhoeal drugs
0.497 0.503 0.000
T47.5 Digestants
0.497 0.503 0.000
T47.3 Saline and osmotic laxatives
0.497 0.503 0.000
T47.2 Stimulant laxatives
0.497 0.503 0.000
T47.0 Histamine H(2)-receptor antagonists
0.497 0.503 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.496 0.503 0.000
T42.1 Iminostilbenes
0.492 0.507 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.487 0.513 0.000
T42.0 Hydantoin derivatives
0.486 0.514 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.486 0.514 0.000
T45.8 Other primarily systemic and haematological agents
0.486 0.514 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.486 0.514 0.000
T45.6 Fibrinolysis-affecting drugs
0.486 0.514 0.000
T45.5 Anticoagulants
0.486 0.514 0.000
T45.4 Iron and its compounds
0.486 0.514 0.000
T45.3 Enzymes, not elsewhere classified
0.486 0.514 0.000
T45.2 Vitamins, not elsewhere classified
0.486 0.514 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.479 0.521 0.000
T50.8 Diagnostic agents
0.469 0.530 0.000
T50.7 Analeptics and opioid receptor antagonists
0.469 0.530 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.469 0.530 0.000
T50.5 Appetite depressants
0.469 0.530 0.000
T50.4 Drugs affecting uric acid metabolism
0.469 0.530 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.469 0.530 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.469 0.530 0.000
T50.1 Loop [high-ceiling] diuretics
0.469 0.530 0.000
T50.0 Mineralocorticoids and their antagonists
0.469 0.530 0.000
E13.8 With unspecified complications
0.000 0.533 0.467
E13.7 With multiple complications
0.000 0.533 0.467
E13.6 With other specified complications
0.000 0.533 0.467
E13.5 With peripheral circulatory complications
0.000 0.533 0.467
E13.4 With neurological complications
0.000 0.533 0.467
E13.3 With ophthalmic complications
0.000 0.533 0.467
E13.2 With renal complications
0.000 0.533 0.467
E13.1 With ketoacidosis
0.000 0.533 0.467
E13.0 With coma
0.000 0.533 0.467
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.461 0.539 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.542 0.458
E50.8 Other manifestations of vitamin A deficiency
0.000 0.542 0.458
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.542 0.458
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.542 0.458
E50.5 Vitamin A deficiency with night blindness
0.000 0.542 0.458
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.542 0.458
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.542 0.458
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.542 0.458
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.542 0.458
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.542 0.458
E51.9 Thiamine deficiency, unspecified
0.000 0.542 0.458
E51.8 Other manifestations of thiamine deficiency
0.000 0.542 0.458
E51.2 Wernicke's encephalopathy
0.000 0.542 0.458
E51.1 Beriberi
0.000 0.542 0.458
E56.9 Vitamin deficiency, unspecified
0.000 0.542 0.458
E56.8 Deficiency of other vitamins
0.000 0.542 0.458
E56.1 Deficiency of vitamin K
0.000 0.542 0.458
E56.0 Deficiency of vitamin E
0.000 0.542 0.458
E63.9 Nutritional deficiency, unspecified
0.000 0.542 0.458
E63.8 Other specified nutritional deficiencies
0.000 0.542 0.458
E63.1 Imbalance of constituents of food intake
0.000 0.542 0.458
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.542 0.458
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.542 0.458
E64.8 Sequelae of other nutritional deficiencies
0.000 0.542 0.458
E64.3 Sequelae of rickets
0.000 0.542 0.458
E64.2 Sequelae of vitamin C deficiency
0.000 0.542 0.458
E64.1 Sequelae of vitamin A deficiency
0.000 0.542 0.458
E64.0 Sequelae of protein-energy malnutrition
0.000 0.542 0.458
T46.1 Calcium-channel blockers
0.453 0.547 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.451 0.548 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.450 0.549 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.450 0.549 0.000
T46.7 Peripheral vasodilators
0.450 0.549 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.450 0.549 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.450 0.549 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.450 0.549 0.000
K90 Intestinal malabsorption
0.000 0.551 0.449
E61.9 Deficiency of nutrient element, unspecified
0.000 0.556 0.443
E61.8 Deficiency of other specified nutrient elements
0.000 0.556 0.443
E61.7 Deficiency of multiple nutrient elements
0.000 0.556 0.443
E61.6 Vanadium deficiency
0.000 0.556 0.443
E61.5 Molybdenum deficiency
0.000 0.556 0.443
E61.4 Chromium deficiency
0.000 0.556 0.443
E61.3 Manganese deficiency
0.000 0.556 0.443
E61.2 Magnesium deficiency
0.000 0.556 0.443
E61.0 Copper deficiency
0.000 0.556 0.443
T39.4 Antirheumatics, not elsewhere classified
0.442 0.558 0.000
T39.2 Pyrazolone derivatives
0.442 0.558 0.000
T38.1 Thyroid hormones and substitutes
0.436 0.563 0.000
E67 Other hyperalimentation
0.000 0.564 0.436
E68 Sequelae of hyperalimentation
0.000 0.564 0.436
T38.9 Other and unspecified hormone antagonists
0.434 0.565 0.000
T38.8 Other and unspecified hormones and their synthetic substitutes
0.434 0.565 0.000
T38.7 Androgens and anabolic congeners
0.434 0.565 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.434 0.565 0.000
T38.5 Other oestrogens and progestogens
0.434 0.565 0.000
T38.4 Oral contraceptives
0.434 0.565 0.000
T38.2 Antithyroid drugs
0.434 0.565 0.000
T38.0 Glucocorticoids and synthetic analogues
0.434 0.565 0.000
E07.8 Other specified disorders of thyroid
0.000 0.571 0.428
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.427 0.573 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.575 0.425
M07.36 Other psoriatic arthropathies (Lower leg)
0.424 0.576 0.000
E66 Obesity
0.000 0.577 0.423
E61.1 Iron deficiency
0.000 0.577 0.423
T43.5 Other and unspecified antipsychotics and neuroleptics
0.415 0.584 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.414 0.585 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.414 0.585 0.000
T37.5 Antiviral drugs
0.414 0.585 0.000
T37.4 Anthelminthics
0.414 0.585 0.000
T37.3 Other antiprotozoal drugs
0.414 0.585 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.414 0.585 0.000
T37.1 Antimycobacterial drugs
0.414 0.585 0.000
T37.0 Sulphonamides
0.414 0.585 0.000
T41.5 Therapeutic gases
0.414 0.585 0.000
T41.4 Anaesthetic, unspecified
0.414 0.585 0.000
T41.3 Local anaesthetics
0.414 0.585 0.000
T41.2 Other and unspecified general anaesthetics
0.414 0.585 0.000
T41.1 Intravenous anaesthetics
0.414 0.585 0.000
T41.0 Inhaled anaesthetics
0.414 0.585 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.414 0.585 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.414 0.585 0.000
T48.5 Anti-common-cold drugs
0.414 0.585 0.000
T48.4 Expectorants
0.414 0.585 0.000
T48.3 Antitussives
0.414 0.585 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.414 0.585 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.414 0.585 0.000
T48.0 Oxytocic drugs
0.414 0.585 0.000
T49.9 Topical agent, unspecified
0.414 0.585 0.000
T49.8 Other topical agents
0.414 0.585 0.000
T49.7 Dental drugs, topically applied
0.414 0.585 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.414 0.585 0.000
T49.5 Ophthalmological drugs and preparations
0.414 0.585 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.414 0.585 0.000
T49.3 Emollients, demulcents and protectants
0.414 0.585 0.000
T49.2 Local astringents and local detergents
0.414 0.585 0.000
T49.1 Antipruritics
0.414 0.585 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.414 0.585 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.408 0.592 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.407 0.592 0.000
E13.9 Without complications
0.000 0.595 0.404
T36.9 Systemic antibiotic, unspecified
0.400 0.599 0.000
T36.8 Other systemic antibiotics
0.400 0.599 0.000
T36.7 Antifungal antibiotics, systemically used
0.400 0.599 0.000
T36.6 Rifamycins
0.400 0.599 0.000
T36.5 Aminoglycosides
0.400 0.599 0.000
T36.4 Tetracyclines
0.400 0.599 0.000
T36.3 Macrolides
0.400 0.599 0.000
T36.2 Chloramphenicol group
0.400 0.599 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.400 0.599 0.000
E66.8 Other obesity
0.000 0.604 0.396
E27 Other disorders of adrenal gland
0.000 0.609 0.391
E27.1 Primary adrenocortical insufficiency
0.000 0.618 0.382
T36.0 Penicillins
0.381 0.619 0.000
T42.4 Benzodiazepines
0.376 0.624 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.001 0.624 0.375
E45 Retarded development following protein-energy malnutrition
0.001 0.624 0.375
E43 Unspecified severe protein-energy malnutrition
0.001 0.624 0.375
E42 Marasmic kwashiorkor
0.001 0.624 0.375
E41 Nutritional marasmus
0.001 0.624 0.375
E40 Kwashiorkor
0.001 0.624 0.375
E14 Unspecified diabetes mellitus
0.000 0.625 0.375
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.371 0.629 0.000
M07.38 Other psoriatic arthropathies (Other)
0.369 0.631 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.369 0.631 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.369 0.631 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.369 0.631 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.369 0.631 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.641 0.359
E65 Localised adiposity
0.000 0.649 0.351
K90.9 Intestinal malabsorption, unspecified
0.000 0.660 0.340
T40.5 Cocaine
0.331 0.669 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.678 0.322
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.678 0.322
K90.1 Tropical sprue
0.000 0.678 0.322
E67.8 Other specified hyperalimentation
0.000 0.687 0.313
E67.3 Hypervitaminosis D
0.000 0.687 0.313
E67.2 Megavitamin-B6 syndrome
0.000 0.687 0.313
E67.1 Hypercarotenaemia
0.000 0.687 0.313
E67.0 Hypervitaminosis A
0.000 0.687 0.313
E22 Hyperfunction of pituitary gland
0.000 0.691 0.309
E04 Other non-toxic goitre
0.000 0.692 0.308
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.695 0.305
E32 Diseases of thymus
0.000 0.695 0.305
E31 Polyglandular dysfunction
0.000 0.695 0.305
E30 Disorders of puberty, not elsewhere classified
0.000 0.695 0.305
E25 Adrenogenital disorders
0.000 0.695 0.305
E66.1 Drug-induced obesity
0.000 0.696 0.303
E34 Other endocrine disorders
0.000 0.699 0.301
E27.8 Other specified disorders of adrenal gland
0.000 0.700 0.300
E14.3 With ophthalmic complications
0.000 0.703 0.297
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.293 0.707 0.000
T40.8 Lysergide [LSD]
0.293 0.707 0.000
T40.7 Cannabis (derivatives)
0.293 0.707 0.000
T40.3 Methadone
0.293 0.707 0.000
T40.1 Heroin
0.293 0.707 0.000
T40.0 Opium
0.293 0.707 0.000
E20 Hypoparathyroidism
0.000 0.713 0.287
E27.2 Addisonian crisis
0.000 0.713 0.287
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.713 0.287
E29 Testicular dysfunction
0.000 0.719 0.281
E27.5 Adrenomedullary hyperfunction
0.000 0.719 0.281
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.719 0.281
E27.0 Other adrenocortical overactivity
0.000 0.719 0.281
T40.4 Other synthetic narcotics
0.274 0.726 0.000
E28 Ovarian dysfunction
0.000 0.727 0.273
E26 Hyperaldosteronism
0.000 0.728 0.272
E44.1 Mild protein-energy malnutrition
0.001 0.731 0.269
E44.0 Moderate protein-energy malnutrition
0.001 0.731 0.269
E14.7 With multiple complications
0.000 0.731 0.269
E14.6 With other specified complications
0.000 0.731 0.269
E14.5 With peripheral circulatory complications
0.000 0.731 0.269
E14.2 Withrenal complications
0.000 0.731 0.269
E14.0 With coma
0.000 0.731 0.269
E22.1 Hyperprolactinaemia
0.000 0.738 0.262
E14.8 With unspecified complications
0.000 0.742 0.258
E14.1 With ketoacidosis
0.000 0.745 0.254
E24 Cushing's syndrome
0.000 0.746 0.254
L40-L45 Papulosquamous disorders
0.253 0.746 0.001
E66.0 Obesity due to excess calories
0.000 0.749 0.251
K90.8 Other intestinal malabsorption
0.000 0.756 0.244
T40.6 Other and unspecified narcotics
0.243 0.757 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.765 0.234
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.776 0.224
M07 Psoriatic and enteropathic arthropathies
0.223 0.777 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.778 0.222
E22.8 Other hyperfunction of pituitary gland
0.000 0.778 0.222
E04.8 Other specified non-toxic goitre
0.000 0.779 0.221
E34.0 Carcinoid syndrome
0.000 0.780 0.219
E25.9 Adrenogenital disorder, unspecified
0.000 0.781 0.219
E25.8 Other adrenogenital disorders
0.000 0.781 0.219
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.781 0.219
E30.9 Disorder of puberty, unspecified
0.000 0.781 0.219
E30.8 Other disorders of puberty
0.000 0.781 0.219
E30.1 Precocious puberty
0.000 0.781 0.219
E30.0 Delayed puberty
0.000 0.781 0.219
E31.9 Polyglandular dysfunction, unspecified
0.000 0.781 0.219
E31.8 Other polyglandular dysfunction
0.000 0.781 0.219
E31.1 Polyglandular hyperfunction
0.000 0.781 0.219
E31.0 Autoimmune polyglandular failure
0.000 0.781 0.219
E32.9 Disease of thymus, unspecified
0.000 0.781 0.219
E32.8 Other diseases of thymus
0.000 0.781 0.219
E32.1 Abscess of thymus
0.000 0.781 0.219
E32.0 Persistent hyperplasia of thymus
0.000 0.781 0.219
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.781 0.219
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.781 0.219
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.781 0.219
E14.4 With neurological complications
0.000 0.784 0.216
E34.5 Androgen resistance syndrome
0.000 0.784 0.216
E34.4 Constitutional tall stature
0.000 0.784 0.216
E34.3 Short stature, not elsewhere classified
0.000 0.784 0.216
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.784 0.216
E34.1 Other hypersecretion of intestinal hormones
0.000 0.784 0.216
E04.9 Non-toxic goitre, unspecified
0.000 0.784 0.215
E34.9 Endocrine disorder, unspecified
0.000 0.785 0.215
E34.8 Other specified endocrine disorders
0.000 0.790 0.210
E28.3 Primary ovarian failure
0.000 0.794 0.206
E20.8 Other hypoparathyroidism
0.000 0.794 0.206
E20.1 Pseudohypoparathyroidism
0.000 0.794 0.206
E20.0 Idiopathic hypoparathyroidism
0.000 0.794 0.206
E29.9 Testicular dysfunction, unspecified
0.000 0.798 0.202
E29.8 Other testicular dysfunction
0.000 0.798 0.202
E29.0 Testicular hyperfunction
0.000 0.798 0.202
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.196 0.804 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.804 0.196
E28.8 Other ovarian dysfunction
0.000 0.804 0.196
E28.1 Androgen excess
0.000 0.804 0.196
E28.0 Oestrogen excess
0.000 0.804 0.196
E22.0 Acromegaly and pituitary gigantism
0.000 0.805 0.195
E26.9 Hyperaldosteronism, unspecified
0.000 0.805 0.195
E26.8 Other hyperaldosteronism
0.000 0.805 0.195
E26.1 Secondary hyperaldosteronism
0.000 0.805 0.195
F33 Recurrent depressive disorder
0.194 0.806 0.000
F33.9 Recurrent depressive disorder, unspecified
0.193 0.807 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.809 0.191
F30-F39 Mood [affective] disorders
0.190 0.810 0.000
L42 Pityriasis rosea
0.188 0.812 0.000
E21.0 Primary hyperparathyroidism
0.000 0.812 0.188
E20.9 Hypoparathyroidism, unspecified
0.000 0.812 0.188
E46 Unspecified protein-energy malnutrition
0.001 0.814 0.185
E04.0 Non-toxic diffuse goitre
0.000 0.816 0.184
E24.8 Other Cushing's syndrome
0.000 0.817 0.182
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.817 0.182
E24.3 Ectopic ACTH syndrome
0.000 0.817 0.182
E24.2 Drug-induced Cushing's syndrome
0.000 0.817 0.182
E24.1 Nelson's syndrome
0.000 0.817 0.182
L44 Other papulosquamous disorders
0.182 0.818 0.001
L41 Parapsoriasis
0.182 0.818 0.001
L45 Papulosquamous disorders in diseases classified elsewhere
0.182 0.818 0.001
Chapter V Mental and behavioural disorders
0.182 0.818 0.000
E29.1 Testicular hypofunction
0.000 0.822 0.178
E27.9 Disorder of adrenal gland, unspecified
0.001 0.823 0.176
F60-F69 Disorders of adult personality and behaviour
0.176 0.824 0.000
F60 Specific personality disorders
0.174 0.826 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.832 0.168
E21.2 Other hyperparathyroidism
0.000 0.832 0.168
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.168 0.832 0.000
F60.3 Emotionally unstable personality disorder
0.165 0.835 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.164 0.836 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.837 0.163
E26.0 Primary hyperaldosteronism
0.000 0.838 0.162
F34 Persistent mood [affective] disorders
0.161 0.839 0.000
M07.6 Other enteropathic arthropathies
0.160 0.840 0.000
M07.5 Arthropathy in ulcerative colitis
0.160 0.840 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.160 0.840 0.000
M07.2 Psoriatic spondylitis
0.160 0.840 0.000
M07.1 Arthritis mutilans
0.160 0.840 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.160 0.840 0.000
F30 Manic episode
0.158 0.842 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.157 0.842 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.843 0.157
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.156 0.844 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.844 0.156
F40 Phobic anxiety disorders
0.155 0.845 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.155 0.845 0.000
F32 Depressive episode
0.154 0.846 0.000
T40.2 Other opioids
0.152 0.848 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.151 0.849 0.000
E21.3 Hyperparathyroidism, unspecified
0.000 0.852 0.148
E28.2 Polycystic ovarian syndrome
0.000 0.853 0.147
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.147 0.853 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.147 0.853 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.854 0.146
F33.1 Recurrent depressive disorder, current episode moderate
0.144 0.856 0.000
F60.7 Dependent personality disorder
0.143 0.856 0.000
F60.5 Anankastic personality disorder
0.143 0.857 0.000
F40.2 Specific (isolated) phobias
0.142 0.858 0.000
F32.0 Mild depressive episode
0.140 0.860 0.000
F50 Eating disorders
0.140 0.860 0.000
F34.1 Dysthymia
0.140 0.860 0.000
F25 Schizoaffective disorders
0.140 0.860 0.000
F48 Other neurotic disorders
0.140 0.860 0.000
F52.2 Failure of genital response
0.139 0.861 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.861 0.139
F33.8 Other recurrent depressive disorders
0.139 0.861 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.139 0.861 0.000
F38 Other mood [affective] disorders
0.136 0.863 0.000
F70-F79 Mental retardation
0.132 0.868 0.000
F60.9 Personality disorder, unspecified
0.131 0.868 0.000
F69 Unspecified disorder of adult personality and behaviour
0.131 0.869 0.000
F30.2 Mania with psychotic symptoms
0.131 0.869 0.000
L41.9 Parapsoriasis, unspecified
0.130 0.869 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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