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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3922717
log Bayes Factor = 74.1852
Chromosome 6   position 27,030,924  (GRCh37) Explore rs3922717 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E03 Other hypothyroidism
0.999 0.001 0.000
E03.9 Hypothyroidism, unspecified
0.999 0.001 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.998 0.002 0.000
E05.9 Thyrotoxicosis, unspecified
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.989 0.011 0.000
E16 Other disorders of pancreatic internal secretion
0.981 0.019 0.000
E16.2 Hypoglycaemia, unspecified
0.975 0.025 0.000
E14 Unspecified diabetes mellitus
0.968 0.032 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.058 0.942
R31 Unspecified haematuria
0.000 0.066 0.934
E10.2 With renal complications
0.909 0.091 0.000
E10.6 With other specified complications
0.908 0.092 0.000
E20-E35 Disorders of other endocrine glands
0.905 0.095 0.000
E14.9 Without complications
0.904 0.096 0.000
E10.4 With neurological complications
0.898 0.102 0.000
E10.3 With ophthalmic complications
0.895 0.105 0.000
E14.3 With ophthalmic complications
0.847 0.153 0.000
E27 Other disorders of adrenal gland
0.826 0.174 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.824 0.176 0.000
E10.8 With unspecified complications
0.816 0.184 0.000
E27.1 Primary adrenocortical insufficiency
0.809 0.191 0.000
E50-E64 Other nutritional deficiencies
0.791 0.209 0.000
E21.3 Hyperparathyroidism, unspecified
0.788 0.212 0.000
K90 Intestinal malabsorption
0.784 0.216 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.773 0.227 0.000
E28 Ovarian dysfunction
0.771 0.229 0.000
E11 Non-insulin-dependent diabetes mellitus
0.771 0.229 0.000
E14.8 With unspecified complications
0.770 0.230 0.000
E10.7 With multiple complications
0.757 0.243 0.000
E14.2 Withrenal complications
0.747 0.253 0.000
E40-E46 Malnutrition
0.739 0.261 0.000
E23 Hypofunction and other disorders of pituitary gland
0.739 0.261 0.000
E11.5 With peripheral circulatory complications
0.735 0.265 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.734 0.266 0.000
E14.6 With other specified complications
0.733 0.267 0.000
E13 Other specified diabetes mellitus
0.731 0.269 0.000
E10.5 With peripheral circulatory complications
0.729 0.271 0.000
E10.1 With ketoacidosis
0.728 0.272 0.000
E06 Thyroiditis
0.725 0.275 0.000
E11.3 With ophthalmic complications
0.722 0.278 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E03.5 Myxoedema coma
0.716 0.284 0.000
E03.4 Atrophy of thyroid (acquired)
0.716 0.284 0.000
E03.3 Postinfectious hypothyroidism
0.716 0.284 0.000
E03.1 Congenital hypothyroidism without goitre
0.716 0.284 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.716 0.284 0.000
E05.5 Thyroid crisis or storm
0.716 0.284 0.000
E05.4 Thyrotoxicosis factitia
0.716 0.284 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.716 0.284 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.716 0.284 0.000
E15 Nondiabetic hypoglycaemic coma
0.709 0.291 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.703 0.296 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.703 0.296 0.000
E16.4 Abnormal secretion of gastrin
0.703 0.296 0.000
E16.3 Increased secretion of glucagon
0.703 0.296 0.000
E03.8 Other specified hypothyroidism
0.699 0.301 0.000
E10.0 With coma
0.697 0.303 0.000
E28.2 Polycystic ovarian syndrome
0.696 0.304 0.000
E14.7 With multiple complications
0.694 0.306 0.000
E14.0 With coma
0.694 0.306 0.000
E14.5 With peripheral circulatory complications
0.691 0.309 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.665 0.334 0.000
E53 Deficiency of other B group vitamins
0.665 0.335 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.664 0.336 0.000
E23.2 Diabetes insipidus
0.664 0.336 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.649 0.351 0.000
E32 Diseases of thymus
0.649 0.351 0.000
E31 Polyglandular dysfunction
0.649 0.351 0.000
E30 Disorders of puberty, not elsewhere classified
0.649 0.351 0.000
E20 Hypoparathyroidism
0.641 0.359 0.000
E16.1 Other hypoglycaemia
0.638 0.361 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.637 0.363 0.000
E25 Adrenogenital disorders
0.636 0.364 0.000
E61 Deficiency of other nutrient elements
0.622 0.378 0.000
E14.1 With ketoacidosis
0.620 0.380 0.000
E14.4 With neurological complications
0.619 0.380 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.612 0.388 0.000
E11.0 With coma
0.612 0.388 0.000
E26 Hyperaldosteronism
0.608 0.392 0.000
E05.8 Other thyrotoxicosis
0.607 0.393 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.605 0.395 0.000
E07 Other disorders of thyroid
0.595 0.405 0.000
E27.5 Adrenomedullary hyperfunction
0.593 0.407 0.000
E27.0 Other adrenocortical overactivity
0.593 0.407 0.000
E21.4 Other specified disorders of parathyroid gland
0.591 0.409 0.000
E21.2 Other hyperparathyroidism
0.591 0.409 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.587 0.413 0.000
E23.6 Other disorders of pituitary gland
0.585 0.415 0.000
E58 Dietary calcium deficiency
0.576 0.424 0.000
K90.9 Intestinal malabsorption, unspecified
0.570 0.430 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.567 0.433 0.000
E63 Other nutritional deficiencies
0.567 0.433 0.000
E56 Other vitamin deficiencies
0.567 0.433 0.000
E51 Thiamine deficiency
0.567 0.433 0.000
E50 Vitamin A deficiency
0.567 0.433 0.000
E60 Dietary zinc deficiency
0.567 0.433 0.000
E59 Dietary selenium deficiency
0.567 0.433 0.000
E54 Ascorbic acid deficiency
0.567 0.433 0.000
E52 Niacin deficiency [pellagra]
0.567 0.433 0.000
K90.8 Other intestinal malabsorption
0.567 0.433 0.000
E11.1 With ketoacidosis
0.563 0.437 0.000
E53.8 Deficiency of other specified B group vitamins
0.562 0.438 0.000
K90.3 Pancreatic steatorrhoea
0.562 0.438 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.562 0.438 0.000
K90.1 Tropical sprue
0.562 0.438 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.561 0.439 0.000
E24 Cushing's syndrome
0.555 0.445 0.000
E28.9 Ovarian dysfunction, unspecified
0.553 0.447 0.000
E28.8 Other ovarian dysfunction
0.553 0.447 0.000
E28.1 Androgen excess
0.553 0.447 0.000
E28.0 Oestrogen excess
0.553 0.447 0.000
E11.7 With multiple complications
0.552 0.447 0.000
E46 Unspecified protein-energy malnutrition
0.551 0.449 0.000
E13.9 Without complications
0.538 0.462 0.000
E06.9 Thyroiditis, unspecified
0.532 0.468 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.530 0.470 0.000
E45 Retarded development following protein-energy malnutrition
0.530 0.470 0.000
E43 Unspecified severe protein-energy malnutrition
0.530 0.470 0.000
E42 Marasmic kwashiorkor
0.530 0.470 0.000
E41 Nutritional marasmus
0.530 0.470 0.000
E40 Kwashiorkor
0.530 0.470 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.530 0.470 0.000
E23.1 Drug-induced hypopituitarism
0.530 0.470 0.000
E11.6 With other specified complications
0.529 0.471 0.000
E06.3 Autoimmune thyroiditis
0.528 0.472 0.000
E13.3 With ophthalmic complications
0.525 0.475 0.000
E13.8 With unspecified complications
0.524 0.476 0.000
E13.7 With multiple complications
0.524 0.476 0.000
E13.6 With other specified complications
0.524 0.476 0.000
E13.5 With peripheral circulatory complications
0.524 0.476 0.000
E13.4 With neurological complications
0.524 0.476 0.000
E13.2 With renal complications
0.524 0.476 0.000
E13.1 With ketoacidosis
0.524 0.476 0.000
E13.0 With coma
0.524 0.476 0.000
E61.1 Iron deficiency
0.523 0.477 0.000
E06.4 Drug-induced thyroiditis
0.520 0.480 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.520 0.480 0.000
E06.1 Subacute thyroiditis
0.520 0.480 0.000
E06.0 Acute thyroiditis
0.520 0.480 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.000 0.487 0.513
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.000 0.487 0.513
E27.2 Addisonian crisis
0.512 0.488 0.000
E29 Testicular dysfunction
0.508 0.492 0.000
K40 Inguinal hernia
0.000 0.492 0.508
E06.5 Other chronic thyroiditis
0.506 0.494 0.000
E53.9 Vitamin B deficiency, unspecified
0.499 0.501 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.496 0.503 0.000
E21.0 Primary hyperparathyroidism
0.493 0.507 0.000
E23.7 Disorder of pituitary gland, unspecified
0.492 0.508 0.000
E28.3 Primary ovarian failure
0.490 0.510 0.000
E34 Other endocrine disorders
0.478 0.522 0.000
E11.8 With unspecified complications
0.477 0.523 0.000
E53.1 Pyridoxine deficiency
0.477 0.523 0.000
E53.0 Riboflavin deficiency
0.477 0.523 0.000
E27.9 Disorder of adrenal gland, unspecified
0.476 0.524 0.000
E30.9 Disorder of puberty, unspecified
0.465 0.535 0.000
E30.8 Other disorders of puberty
0.465 0.535 0.000
E30.1 Precocious puberty
0.465 0.535 0.000
E30.0 Delayed puberty
0.465 0.535 0.000
E31.9 Polyglandular dysfunction, unspecified
0.465 0.535 0.000
E31.8 Other polyglandular dysfunction
0.465 0.535 0.000
E31.1 Polyglandular hyperfunction
0.465 0.535 0.000
E31.0 Autoimmune polyglandular failure
0.465 0.535 0.000
E32.9 Disease of thymus, unspecified
0.465 0.535 0.000
E32.8 Other diseases of thymus
0.465 0.535 0.000
E32.1 Abscess of thymus
0.465 0.535 0.000
E32.0 Persistent hyperplasia of thymus
0.465 0.535 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.465 0.535 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.465 0.535 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.465 0.535 0.000
E20.8 Other hypoparathyroidism
0.459 0.540 0.000
E20.1 Pseudohypoparathyroidism
0.459 0.540 0.000
E20.0 Idiopathic hypoparathyroidism
0.459 0.540 0.000
E25.9 Adrenogenital disorder, unspecified
0.456 0.544 0.000
E25.8 Other adrenogenital disorders
0.456 0.544 0.000
E20.9 Hypoparathyroidism, unspecified
0.451 0.548 0.000
E24.2 Drug-induced Cushing's syndrome
0.448 0.552 0.000
E61.9 Deficiency of nutrient element, unspecified
0.446 0.554 0.000
E61.8 Deficiency of other specified nutrient elements
0.446 0.554 0.000
E61.7 Deficiency of multiple nutrient elements
0.446 0.554 0.000
E61.6 Vanadium deficiency
0.446 0.554 0.000
E61.5 Molybdenum deficiency
0.446 0.554 0.000
E61.4 Chromium deficiency
0.446 0.554 0.000
E61.3 Manganese deficiency
0.446 0.554 0.000
E61.0 Copper deficiency
0.446 0.554 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.443 0.556 0.000
E22 Hyperfunction of pituitary gland
0.440 0.560 0.000
E26.9 Hyperaldosteronism, unspecified
0.436 0.564 0.000
E26.8 Other hyperaldosteronism
0.436 0.564 0.000
E26.1 Secondary hyperaldosteronism
0.436 0.564 0.000
E55 Vitamin D deficiency
0.427 0.572 0.000
E07.1 Dyshormogenetic goitre
0.426 0.573 0.000
E07.0 Hypersecretion of calcitonin
0.426 0.573 0.000
E04 Other non-toxic goitre
0.425 0.575 0.000
E65-E68 Obesity and other hyperalimentation
0.418 0.582 0.000
E50.9 Vitamin A deficiency, unspecified
0.407 0.593 0.000
E50.8 Other manifestations of vitamin A deficiency
0.407 0.593 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.407 0.593 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.407 0.593 0.000
E50.5 Vitamin A deficiency with night blindness
0.407 0.593 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.407 0.593 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.407 0.593 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.407 0.593 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.407 0.593 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.407 0.593 0.000
E51.9 Thiamine deficiency, unspecified
0.407 0.593 0.000
E51.8 Other manifestations of thiamine deficiency
0.407 0.593 0.000
E51.2 Wernicke's encephalopathy
0.407 0.593 0.000
E51.1 Beriberi
0.407 0.593 0.000
E56.9 Vitamin deficiency, unspecified
0.407 0.593 0.000
E56.8 Deficiency of other vitamins
0.407 0.593 0.000
E56.1 Deficiency of vitamin K
0.407 0.593 0.000
E56.0 Deficiency of vitamin E
0.407 0.593 0.000
E63.9 Nutritional deficiency, unspecified
0.407 0.593 0.000
E63.8 Other specified nutritional deficiencies
0.407 0.593 0.000
E63.1 Imbalance of constituents of food intake
0.407 0.593 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.407 0.593 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.407 0.593 0.000
E64.8 Sequelae of other nutritional deficiencies
0.407 0.593 0.000
E64.3 Sequelae of rickets
0.407 0.593 0.000
E64.2 Sequelae of vitamin C deficiency
0.407 0.593 0.000
E64.1 Sequelae of vitamin A deficiency
0.407 0.593 0.000
E64.0 Sequelae of protein-energy malnutrition
0.407 0.593 0.000
E61.2 Magnesium deficiency
0.406 0.594 0.000
E07.8 Other specified disorders of thyroid
0.403 0.596 0.000
E24.8 Other Cushing's syndrome
0.398 0.602 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.398 0.602 0.000
E24.3 Ectopic ACTH syndrome
0.398 0.602 0.000
E24.1 Nelson's syndrome
0.398 0.602 0.000
E26.0 Primary hyperaldosteronism
0.395 0.604 0.000
E04.9 Non-toxic goitre, unspecified
0.393 0.607 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.000 0.615 0.385
E44.1 Mild protein-energy malnutrition
0.380 0.620 0.000
E44.0 Moderate protein-energy malnutrition
0.380 0.620 0.000
E29.9 Testicular dysfunction, unspecified
0.364 0.636 0.000
E29.8 Other testicular dysfunction
0.364 0.636 0.000
E29.0 Testicular hyperfunction
0.364 0.636 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.000 0.636 0.364
K40.1 Bilateral inguinal hernia, with gangrene
0.000 0.636 0.364
E23.0 Hypopituitarism
0.356 0.644 0.000
E34.8 Other specified endocrine disorders
0.353 0.647 0.000
E22.1 Hyperprolactinaemia
0.350 0.650 0.000
E34.5 Androgen resistance syndrome
0.343 0.657 0.000
E34.4 Constitutional tall stature
0.343 0.657 0.000
E34.3 Short stature, not elsewhere classified
0.343 0.657 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.343 0.657 0.000
E34.1 Other hypersecretion of intestinal hormones
0.343 0.657 0.000
D64.9 Anaemia, unspecified
0.342 0.658 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.000 0.660 0.340
E07.9 Disorder of thyroid, unspecified
0.339 0.661 0.000
E24.0 Pituitary-dependent Cushing's disease
0.336 0.663 0.000
E27.8 Other specified disorders of adrenal gland
0.333 0.667 0.001
I83 Varicose veins of lower extremities
0.000 0.669 0.331
E22.9 Hyperfunction of pituitary gland, unspecified
0.315 0.684 0.000
E22.8 Other hyperfunction of pituitary gland
0.315 0.684 0.000
E55.0 Rickets, active
0.307 0.693 0.000
E04.8 Other specified non-toxic goitre
0.305 0.695 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.699 0.301
E67 Other hyperalimentation
0.300 0.700 0.000
E68 Sequelae of hyperalimentation
0.300 0.700 0.000
E24.9 Cushing's syndrome, unspecified
0.290 0.710 0.000
E34.0 Carcinoid syndrome
0.268 0.732 0.000
E34.9 Endocrine disorder, unspecified
0.264 0.735 0.000
E29.1 Testicular hypofunction
0.223 0.777 0.000
E65 Localised adiposity
0.218 0.782 0.000
E22.0 Acromegaly and pituitary gigantism
0.217 0.783 0.000
E67.8 Other specified hyperalimentation
0.215 0.785 0.000
E67.3 Hypervitaminosis D
0.215 0.785 0.000
E67.2 Megavitamin-B6 syndrome
0.215 0.785 0.000
E67.1 Hypercarotenaemia
0.215 0.785 0.000
E67.0 Hypervitaminosis A
0.215 0.785 0.000
E11.2 With renal complications
0.210 0.789 0.001
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.183 0.816 0.000
E11.9 Without complications
0.174 0.826 0.000
E66 Obesity
0.171 0.829 0.000
E04.0 Non-toxic diffuse goitre
0.168 0.831 0.001
E04.1 Non-toxic single thyroid nodule
0.168 0.831 0.000
E55.9 Vitamin D deficiency, unspecified
0.167 0.833 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.833 0.166
D64 Other anaemias
0.159 0.841 0.000
E11.4 With neurological complications
0.155 0.845 0.000
E66.8 Other obesity
0.130 0.870 0.000
K40-K46 Hernia
0.000 0.871 0.129
K44 Diaphragmatic hernia
0.000 0.872 0.128
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.000 0.873 0.127
E66.0 Obesity due to excess calories
0.124 0.876 0.000
E66.1 Drug-induced obesity
0.123 0.877 0.000
D64.4 Congenital dyserythropoietic anaemia
0.114 0.886 0.000
D64.3 Other sideroblastic anaemias
0.114 0.886 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.114 0.886 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.114 0.886 0.000
D64.0 Hereditary sideroblastic anaemia
0.114 0.886 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.111 0.889 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.896 0.104
D64.8 Other specified anaemias
0.098 0.901 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.902 0.098
K44.1 Diaphragmatic hernia with gangrene
0.000 0.908 0.092
E83 Disorders of mineral metabolism
0.030 0.910 0.060
E04.2 Non-toxic multinodular goitre
0.088 0.912 0.000
K46 Unspecified abdominal hernia
0.000 0.919 0.081
K41 Femoral hernia
0.000 0.933 0.067
H34 Retinal vascular occlusions
0.065 0.935 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.022 0.935 0.043
E83.8 Other disorders of mineral metabolism
0.022 0.935 0.043
E83.2 Disorders of zinc metabolism
0.022 0.935 0.043
E83.0 Disorders of copper metabolism
0.022 0.935 0.043
H34.8 Other retinal vascular occlusions
0.065 0.935 0.000
K45 Other abdominal hernia
0.000 0.936 0.064
H36.0 Diabetic retinopathy
0.062 0.938 0.000
H30-H36 Disorders of choroid and retina
0.061 0.939 0.000
H36 Retinal disorders in diseases classified elsewhere
0.061 0.939 0.000
D60-D64 Aplastic and other anaemias
0.061 0.939 0.000
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.942 0.058
H34.2 Other retinal artery occlusions
0.058 0.942 0.000
H35.8 Other specified retinal disorders
0.058 0.942 0.000
E70-E90 Metabolic disorders
0.055 0.944 0.001
H35 Other retinal disorders
0.056 0.944 0.000
E83.3 Disorders of phosphorus metabolism
0.015 0.946 0.039
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.946 0.054
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.948 0.052
H34.1 Central retinal artery occlusion
0.051 0.948 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.950 0.050
K51 Ulcerative colitis
0.000 0.950 0.050
K90-K93 Other diseases of the digestive system
0.048 0.950 0.002
H35.4 Peripheral retinal degeneration
0.050 0.950 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.951 0.049
H34.9 Retinal vascular occlusion, unspecified
0.048 0.952 0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.952 0.048
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.952 0.048
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.952 0.048
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.952 0.048
H35.0 Background retinopathy and retinal vascular changes
0.048 0.952 0.000
H34.0 Transient retinal artery occlusion
0.047 0.953 0.000
K45.1 Other specified abdominal hernia with gangrene
0.000 0.954 0.046
K51.8 Other ulcerative colitis
0.000 0.954 0.046
K43 Ventral hernia
0.000 0.954 0.046
H30 Chorioretinal inflammation
0.045 0.955 0.000
H31 Other disorders of choroid
0.045 0.955 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.044 0.956 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.044 0.956 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.044 0.956 0.000
K51.2 Ulcerative (chronic) proctitis
0.000 0.956 0.044
H35.7 Separation of retinal layers
0.043 0.957 0.000
L30.9 Dermatitis, unspecified
0.043 0.957 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.043 0.957 0.000
K51.5 Mucosal proctocolitis
0.000 0.957 0.043
E84 Cystic fibrosis
0.041 0.958 0.001
E79 Disorders of purine and pyrimidine metabolism
0.040 0.959 0.001
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.959 0.041
E77 Disorders of glycoprotein metabolism
0.040 0.959 0.001
E76 Disorders of glycosaminoglycan metabolism
0.040 0.959 0.001
E72 Other disorders of amino-acid metabolism
0.040 0.959 0.001
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.040 0.959 0.001
E70 Disorders of aromatic amino-acid metabolism
0.040 0.959 0.001
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.040 0.959 0.001
H35.1 Retinopathy of prematurity
0.041 0.959 0.000
E73 Lactose intolerance
0.040 0.960 0.001
D50-D53 Nutritional anaemias
0.040 0.960 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.960 0.040
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.039 0.960 0.001
K51.9 Ulcerative colitis, unspecified
0.000 0.960 0.040
D63 Anaemia in chronic diseases classified elsewhere
0.040 0.960 0.000
K51.4 Pseudopolyposis of colon
0.000 0.961 0.039
H47 Other disorders of optic [2nd] nerve and visual pathways
0.039 0.961 0.000
E87.0 Hyperosmolality and hypernatraemia
0.039 0.961 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.961 0.038
E87 Other disorders of fluid, electrolyte and acid-base balance
0.038 0.962 0.000
H47.0 Disorders of optic nerve, not elsewhere classified
0.038 0.962 0.000
H35.6 Retinal haemorrhage
0.038 0.962 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.037 0.962 0.001
L30 Other dermatitis
0.038 0.962 0.000
E85 Amyloidosis
0.037 0.962 0.001
W20-W49 Exposure to inanimate mechanical forces
0.038 0.962 0.000
E74 Other disorders of carbohydrate metabolism
0.036 0.963 0.001
H46-H48 Disorders of optic nerve and visual pathways
0.037 0.963 0.000
D50 Iron deficiency anaemia
0.037 0.963 0.000
L43.9 Lichen planus, unspecified
0.037 0.963 0.000
H35.2 Other proliferative retinopathy
0.036 0.963 0.000
D50.8 Other iron deficiency anaemias
0.037 0.963 0.000
E89.2 Postprocedural hypoparathyroidism
0.036 0.963 0.000
D51 Vitamin B12 deficiency anaemia
0.036 0.964 0.000
D80-D89 Certain disorders involving the immune mechanism
0.036 0.964 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.035 0.964 0.001
E83.4 Disorders of magnesium metabolism
0.025 0.964 0.010
W49 Exposure to other and unspecified inanimate mechanical forces
0.035 0.965 0.000
D61 Other aplastic anaemias
0.035 0.965 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.035 0.965 0.000
E87.7 Fluid overload
0.035 0.965 0.000
Chapter VII Diseases of the eye and adnexa
0.035 0.965 0.000
H31.9 Disorder of choroid, unspecified
0.035 0.965 0.000
H47.3 Other disorders of optic disk
0.035 0.965 0.000
W22 Striking against or struck by other objects
0.035 0.965 0.000
Chapter XX External causes of morbidity and mortality
0.034 0.966 0.000
H47.2 Optic atrophy
0.034 0.966 0.000
H31.0 Chorioretinal scars
0.034 0.966 0.000
W49.0 Home
0.034 0.966 0.000
L43 Lichen planus
0.033 0.967 0.000
D55-D59 Haemolytic anaemias
0.033 0.967 0.000
V10-V19 Pedal cyclist injured in transport accident
0.033 0.967 0.000
H31.8 Other specified disorders of choroid
0.033 0.967 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.967 0.033
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.967 0.033
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.967 0.033
K43.4 Parastomal hernia with gangrene
0.000 0.967 0.033
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.967 0.033
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.967 0.033
K43.1 Ventral hernia with gangrene
0.000 0.967 0.033
L30.8 Other specified dermatitis
0.033 0.967 0.000
H30.9 Chorioretinal inflammation, unspecified
0.033 0.967 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.033 0.967 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.033 0.967 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.032 0.968 0.000
E87.3 Alkalosis
0.032 0.968 0.000
H30.8 Other chorioretinal inflammations
0.032 0.968 0.000
H30.2 Posterior cyclitis
0.032 0.968 0.000
H30.1 Disseminated chorioretinal inflammation
0.032 0.968 0.000
H30.0 Focal chorioretinal inflammation
0.032 0.968 0.000
X20-X29 Contact with venomous animals and plants
0.032 0.968 0.000
H31.4 Choroidal detachment
0.032 0.968 0.000
H31.2 Hereditary choroidal dystrophy
0.032 0.968 0.000
V18.0 Driver injured in nontraffic accident
0.032 0.968 0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.032 0.968 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.032 0.968 0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene
0.001 0.968 0.031
X23.9 Unspecified place
0.032 0.968 0.000
D60.9 Acquired pure red cell aplasia, unspecified
0.031 0.968 0.000
D60.8 Other acquired pure red cell aplasias
0.031 0.968 0.000
D60.1 Transient acquired pure red cell aplasia
0.031 0.968 0.000
D60.0 Chronic acquired pure red cell aplasia
0.031 0.968 0.000
L20-L30 Dermatitis and eczema
0.032 0.968 0.000
X23 Contact with hornets, wasps and bees
0.031 0.969 0.000
S20-S29 Injuries to the thorax
0.031 0.969 0.000
E84.9 Cystic fibrosis, unspecified
0.031 0.969 0.001
K42 Umbilical hernia
0.000 0.969 0.031
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.031 0.969 0.000
# Top node
0.031 0.969 0.000
H31.3 Choroidal haemorrhage and rupture
0.031 0.969 0.000
S21 Open wound of thorax
0.031 0.969 0.000
W29 Contact with other powered hand tools and household machinery
0.031 0.969 0.000
L40-L45 Papulosquamous disorders
0.031 0.969 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.030 0.970 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.030 0.970 0.001
E84.8 Cystic fibrosis with other manifestations
0.029 0.970 0.001
E84.1 Cystic fibrosis with intestinal manifestations
0.029 0.970 0.001
E84.0 Cystic fibrosis with pulmonary manifestations
0.029 0.970 0.001
V01-V09 Pedestrian injured in transport accident
0.030 0.970 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.029 0.970 0.001
E79.8 Other disorders of purine and pyrimidine metabolism
0.029 0.970 0.001
E79.1 Lesch-Nyhan syndrome
0.029 0.970 0.001
S21.9 Open wound of thorax, part unspecified
0.030 0.970 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.029 0.971 0.001
E70.8 Other disorders of aromatic amino-acid metabolism
0.029 0.971 0.001
E70.3 Albinism
0.029 0.971 0.001
E70.2 Disorders of tyrosine metabolism
0.029 0.971 0.001
E70.1 Other hyperphenylalaninaemias
0.029 0.971 0.001
E70.0 Classical phenylketonuria
0.029 0.971 0.001
E71.3 Disorders of fatty-acid metabolism
0.029 0.971 0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.029 0.971 0.001
E71.1 Other disorders of branched-chain amino-acid metabolism
0.029 0.971 0.001
E71.0 Maple-syrup-urine disease
0.029 0.971 0.001
E72.9 Disorder of amino-acid metabolism, unspecified
0.029 0.971 0.001
E72.8 Other specified disorders of amino-acid metabolism
0.029 0.971 0.001
E72.5 Disorders of glycine metabolism
0.029 0.971 0.001
E72.4 Disorders of ornithine metabolism
0.029 0.971 0.001
E72.3 Disorders of lysine and hydroxylysine metabolism
0.029 0.971 0.001
E72.2 Disorders of urea cycle metabolism
0.029 0.971 0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.029 0.971 0.001
E72.0 Disorders of amino-acid transport
0.029 0.971 0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.029 0.971 0.001
E76.8 Other disorders of glucosaminoglycan metabolism
0.029 0.971 0.001
E76.3 Mucopolysaccharidosis, unspecified
0.029 0.971 0.001
E76.2 Other mucopolysaccharidoses
0.029 0.971 0.001
E76.1 Mucopolysaccharidosis, type II
0.029 0.971 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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