TreeWAS – Variant ID: rs3923809

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Q61.3 Polycystic kidney, unspecified	0.000	0.738	0.262
Q61 Cystic kidney disease	0.000	0.775	0.225
Q61.2 Polycystic kidney, adult type	0.000	0.776	0.224
Q61.8 Other cystic kidney diseases	0.000	0.838	0.161
Q61.1 Polycystic kidney, infantile type	0.000	0.838	0.161
Q61.4 Renal dysplasia	0.000	0.839	0.161
Q61.9 Cystic kidney disease, unspecified	0.000	0.850	0.150
Q61.5 Medullary cystic kidney	0.000	0.855	0.145
Q61.0 Congenital single renal cyst	0.000	0.893	0.107
Q60-Q64 Congenital malformations of the urinary system	0.000	0.933	0.067
Q60 Renal agenesis and other reduction defects of kidney	0.000	0.944	0.056
J38.7 Other diseases of larynx	0.048	0.952	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.954	0.046
Q60.2 Renal agenesis, unspecified	0.000	0.955	0.044
Q64 Other congenital malformations of urinary system	0.000	0.956	0.044
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.000	0.958	0.042
Q60.6 Potter's syndrome	0.000	0.959	0.041
Q60.5 Renal hypoplasia, unspecified	0.000	0.959	0.041
Q60.4 Renal hypoplasia, bilateral	0.000	0.959	0.041
Q60.3 Renal hypoplasia, unilateral	0.000	0.959	0.041
Q60.1 Renal agenesis, bilateral	0.000	0.959	0.041
E23 Hypofunction and other disorders of pituitary gland	0.000	0.967	0.033
Q64.9 Congenital malformation of urinary system, unspecified	0.000	0.968	0.032
Q64.8 Other specified congenital malformations of urinary system	0.000	0.968	0.032
Q64.7 Other congenital malformations of bladder and urethra	0.000	0.968	0.032
Q64.6 Congenital diverticulum of bladder	0.000	0.968	0.032
Q64.5 Congenital absence of bladder and urethra	0.000	0.968	0.032
Q64.4 Malformation of urachus	0.000	0.968	0.032
Q64.2 Congenital posterior urethral valves	0.000	0.968	0.032
Q64.1 Exstrophy of urinary bladder	0.000	0.968	0.032
Q64.0 Epispadias	0.000	0.968	0.032
E23.0 Hypopituitarism	0.000	0.968	0.032
E23.2 Diabetes insipidus	0.000	0.969	0.031
Q62.8 Other congenital malformations of ureter	0.000	0.970	0.030
Q62.7 Congenital vesico-uretero-renal reflux	0.000	0.970	0.030
Q62.6 Malposition of ureter	0.000	0.970	0.030
Q62.4 Agenesis of ureter	0.000	0.970	0.030
Q62.3 Other obstructive defects of renal pelvis and ureter	0.000	0.970	0.030
Q62.2 Congenital megaloureter	0.000	0.970	0.030
Q62.1 Atresia and stenosis of ureter	0.000	0.970	0.030
Q62.0 Congenital hydronephrosis	0.000	0.970	0.030
E29.1 Testicular hypofunction	0.000	0.971	0.029
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.000	0.972	0.028
E29 Testicular dysfunction	0.000	0.972	0.028
E20-E35 Disorders of other endocrine glands	0.000	0.972	0.028
E23.7 Disorder of pituitary gland, unspecified	0.000	0.973	0.027
E24 Cushing's syndrome	0.000	0.974	0.026
E23.6 Other disorders of pituitary gland	0.000	0.975	0.025
Q63 Other congenital malformations of kidney	0.000	0.976	0.024
Q62.5 Duplication of ureter	0.000	0.976	0.023
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.976	0.024
E23.1 Drug-induced hypopituitarism	0.000	0.976	0.024
E22 Hyperfunction of pituitary gland	0.000	0.977	0.023
E27 Other disorders of adrenal gland	0.000	0.977	0.023
E24.9 Cushing's syndrome, unspecified	0.000	0.977	0.023
E24.0 Pituitary-dependent Cushing's disease	0.000	0.978	0.022
E24.2 Drug-induced Cushing's syndrome	0.000	0.979	0.021
E25 Adrenogenital disorders	0.000	0.979	0.021
E22.1 Hyperprolactinaemia	0.000	0.979	0.021
E29.9 Testicular dysfunction, unspecified	0.000	0.980	0.020
E29.8 Other testicular dysfunction	0.000	0.980	0.020
E29.0 Testicular hyperfunction	0.000	0.980	0.020
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.980	0.020
E32 Diseases of thymus	0.000	0.980	0.020
E31 Polyglandular dysfunction	0.000	0.980	0.020
E30 Disorders of puberty, not elsewhere classified	0.000	0.980	0.020
E20 Hypoparathyroidism	0.000	0.981	0.019
E24.8 Other Cushing's syndrome	0.000	0.981	0.019
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.981	0.019
E24.3 Ectopic ACTH syndrome	0.000	0.981	0.019
E24.1 Nelson's syndrome	0.000	0.981	0.019
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.982	0.018
E27.1 Primary adrenocortical insufficiency	0.000	0.982	0.018
E27.9 Disorder of adrenal gland, unspecified	0.000	0.983	0.017
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.983	0.017
Q63.8 Other specified congenital malformations of kidney	0.000	0.983	0.017
Q63.3 Hyperplastic and giant kidney	0.000	0.983	0.017
E27.8 Other specified disorders of adrenal gland	0.000	0.983	0.017
E26 Hyperaldosteronism	0.000	0.983	0.017
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.983	0.017
E22.8 Other hyperfunction of pituitary gland	0.000	0.983	0.017
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.983	0.017
E34 Other endocrine disorders	0.000	0.983	0.017
E27.5 Adrenomedullary hyperfunction	0.000	0.983	0.017
E27.0 Other adrenocortical overactivity	0.000	0.983	0.017
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.983	0.017
E22.0 Acromegaly and pituitary gigantism	0.000	0.984	0.016
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.984	0.016
E25.9 Adrenogenital disorder, unspecified	0.000	0.985	0.015
E25.8 Other adrenogenital disorders	0.000	0.985	0.015
E27.2 Addisonian crisis	0.000	0.985	0.015
I07.1 Tricuspid insufficiency	0.015	0.985	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.015	0.985	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.985	0.014
E30.8 Other disorders of puberty	0.000	0.985	0.014
E30.1 Precocious puberty	0.000	0.985	0.014
E30.0 Delayed puberty	0.000	0.985	0.014
E31.9 Polyglandular dysfunction, unspecified	0.000	0.985	0.014
E31.8 Other polyglandular dysfunction	0.000	0.985	0.014
E31.1 Polyglandular hyperfunction	0.000	0.985	0.014
E31.0 Autoimmune polyglandular failure	0.000	0.985	0.014
E32.9 Disease of thymus, unspecified	0.000	0.985	0.014
E32.8 Other diseases of thymus	0.000	0.985	0.014
E32.1 Abscess of thymus	0.000	0.985	0.014
E32.0 Persistent hyperplasia of thymus	0.000	0.985	0.014
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.985	0.014
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.985	0.014
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.985	0.014
I21.4 Acute subendocardial myocardial infarction	0.000	0.986	0.014
Z57.5 Occupational exposure to toxic agents in other industries	0.014	0.986	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.986	0.014
E20.8 Other hypoparathyroidism	0.000	0.986	0.014
E20.1 Pseudohypoparathyroidism	0.000	0.986	0.014
E20.0 Idiopathic hypoparathyroidism	0.000	0.986	0.014
Q63.2 Ectopic kidney	0.001	0.986	0.013
Z57 Occupational exposure to risk-factors	0.013	0.987	0.000
E26.9 Hyperaldosteronism, unspecified	0.000	0.987	0.013
E26.8 Other hyperaldosteronism	0.000	0.987	0.012
E26.1 Secondary hyperaldosteronism	0.000	0.987	0.012
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.987	0.013
E20.9 Hypoparathyroidism, unspecified	0.000	0.987	0.012
Z57.3 Occupational exposure to other air contaminants	0.012	0.988	0.000
E34.5 Androgen resistance syndrome	0.000	0.988	0.012
E34.4 Constitutional tall stature	0.000	0.988	0.012
E34.3 Short stature, not elsewhere classified	0.000	0.988	0.012
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.988	0.012
E34.1 Other hypersecretion of intestinal hormones	0.000	0.988	0.012
E34.0 Carcinoid syndrome	0.000	0.988	0.012
J38.5 Laryngeal spasm	0.012	0.988	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.988	0.012
E34.8 Other specified endocrine disorders	0.000	0.988	0.012
H54.7 Unspecified visual loss	0.012	0.988	0.000
Z59 Problems related to housing and economic circumstances	0.012	0.988	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.012	0.988	0.000
H54 Blindness and low vision	0.011	0.989	0.000
J38.4 Oedema of larynx	0.011	0.989	0.000
Q63.0 Accessory kidney	0.000	0.989	0.011
Z57.8 Occupational exposure to other risk-factors	0.011	0.989	0.000
H54.0 Blindness, both eyes	0.011	0.989	0.000
E28 Ovarian dysfunction	0.000	0.989	0.011
Z59.8 Other problems relating to housing and economic circumstances	0.011	0.989	0.000
J38.0 Paralysis of vocal cords and larynx	0.011	0.989	0.000
J38.2 Nodules of vocal cords	0.011	0.989	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.989	0.011
Q50-Q56 Congenital malformations of genital organs	0.000	0.989	0.011
Z63 Other problems related to primary support group, including family circumstances	0.011	0.989	0.000
Q80-Q89 Other congenital malformations	0.000	0.990	0.010
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.000	0.990	0.010
H54.1 Blindness, one eye, low vision, other eye	0.010	0.990	0.000
Z56 Problems related to employment and unemployment	0.010	0.990	0.000
C67.9 Bladder, unspecified	0.010	0.990	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.990	0.010
Z59.0 Homelessness	0.010	0.990	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.010	0.990	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.010	0.990	0.000
Z57.7 Occupational exposure to vibration	0.010	0.990	0.000
Z57.6 Occupational exposure to extreme temperature	0.010	0.990	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.010	0.990	0.000
Z57.1 Occupational exposure to radiation	0.010	0.990	0.000
Z57.0 Occupational exposure to noise	0.010	0.990	0.000
Z63.8 Other specified problems related to primary support group	0.010	0.990	0.000
Z49.0 Preparatory care for dialysis	0.000	0.990	0.010
E34.9 Endocrine disorder, unspecified	0.000	0.990	0.009
J38.1 Polyp of vocal cord and larynx	0.010	0.990	0.000
H54.5 Low vision, one eye	0.009	0.991	0.000
J38.6 Stenosis of larynx	0.009	0.991	0.000
H54.4 Blindness, one eye	0.009	0.991	0.000
E26.0 Primary hyperaldosteronism	0.000	0.991	0.009
Z61 Problems related to negative life events in childhood	0.009	0.991	0.000
Z63.7 Other stressful life events affecting family and household	0.009	0.991	0.000
Q53 Undescended testicle	0.000	0.991	0.009
J38.3 Other diseases of vocal cords	0.009	0.991	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.991	0.009
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.991	0.009
S27.0 Traumatic pneumothorax	0.000	0.991	0.009
Q30-Q34 Congenital malformations of the respiratory system	0.000	0.991	0.009
E10 Insulin-dependent diabetes mellitus	0.009	0.991	0.000
Z49 Care involving dialysis	0.000	0.991	0.009
Z56.6 Other physical and mental strain related to work	0.009	0.991	0.000
Z65 Problems related to other psychosocial circumstances	0.009	0.991	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.000	0.991	0.009
Z49.1 Extracorporeal dialysis	0.000	0.991	0.009
Z59.7 Insufficient social insurance and welfare support	0.009	0.991	0.000
Z59.6 Low income	0.009	0.991	0.000
Z59.5 Extreme poverty	0.009	0.991	0.000
Z59.4 Lack of adequate food	0.009	0.991	0.000
Z59.3 Problems related to living in residential institution	0.009	0.991	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.009	0.991	0.000
Z64 Problems related to certain psychosocial circumstances	0.009	0.991	0.000
E10.3 With ophthalmic complications	0.009	0.991	0.000
Z62 Other problems related to upbringing	0.009	0.991	0.000
Z55 Problems related to education and literacy	0.009	0.991	0.000
Z63.4 Disappearance and death of family member	0.009	0.991	0.000
C67.3 Anterior wall of bladder	0.009	0.991	0.000
Q51.3 Bicornate uterus	0.000	0.991	0.009
C67 Malignant neoplasm of bladder	0.009	0.991	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.000	0.991	0.008
Q89 Other congenital malformations, not elsewhere classified	0.000	0.991	0.008
Z59.1 Inadequate housing	0.008	0.991	0.000
Z58 Problems related to physical environment	0.008	0.991	0.000
H54.3 Unqualified visual loss, both eyes	0.008	0.992	0.000
Q96 Turner's syndrome	0.000	0.992	0.008
Q51.2 Other doubling of uterus	0.000	0.992	0.008
Z49.2 Other dialysis	0.000	0.992	0.008
Q82 Other congenital malformations of skin	0.000	0.992	0.008
Q35-Q37 Cleft lip and cleft palate	0.000	0.992	0.008
E10.9 Without complications	0.008	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.000	0.992	0.008
E28.8 Other ovarian dysfunction	0.000	0.992	0.008
E28.1 Androgen excess	0.000	0.992	0.008
E28.0 Oestrogen excess	0.000	0.992	0.008
H54.6 Unqualified visual loss, one eye	0.008	0.992	0.000
H54.2 Low vision, both eyes	0.008	0.992	0.000
Q53.1 Undescended testicle, unilateral	0.000	0.992	0.008
Q54 Hypospadias	0.000	0.992	0.008
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.992	0.008
E21.2 Other hyperparathyroidism	0.000	0.992	0.008
Z63.6 Dependent relative needing care at home	0.008	0.992	0.000
E10.5 With peripheral circulatory complications	0.008	0.992	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.992	0.008
Z56.0 Unemployment, unspecified	0.008	0.992	0.000
E10.4 With neurological complications	0.008	0.992	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.992	0.008
Q55 Other congenital malformations of male genital organs	0.000	0.992	0.008
Q83 Congenital malformations of breast	0.000	0.992	0.008
Z63.9 Problem related to primary support group, unspecified	0.008	0.992	0.000
Z63.3 Absence of family member	0.008	0.992	0.000
Z63.2 Inadequate family support	0.008	0.992	0.000
Z63.1 Problems in relationship with parents and in-laws	0.008	0.992	0.000
H53.4 Visual field defects	0.008	0.992	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.000	0.992	0.008
Q84 Other congenital malformations of integument	0.000	0.992	0.008
Q81 Epidermolysis bullosa	0.000	0.992	0.008
Q80 Congenital ichthyosis	0.000	0.992	0.008
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.992	0.008
Q87.4 Marfan's syndrome	0.000	0.992	0.008
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.008	0.992	0.000
E10.0 With coma	0.008	0.992	0.000
H53.9 Visual disturbance, unspecified	0.008	0.992	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.000	0.992	0.007
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.000	0.992	0.007
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.000	0.992	0.007
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.000	0.992	0.007
Q91 Edwards' syndrome and Patau's syndrome	0.000	0.992	0.007
Q90 Down's syndrome	0.000	0.992	0.007
E21.4 Other specified disorders of parathyroid gland	0.000	0.992	0.007
Z56.7 Other and unspecified problems related to employment	0.007	0.992	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.992	0.007
Z56.5 Uncongenial work	0.007	0.992	0.000
Z56.4 Discord with boss and workmates	0.007	0.992	0.000
Z56.2 Threat of job loss	0.007	0.992	0.000
Z56.1 Change of job	0.007	0.992	0.000
Q82.8 Other specified congenital malformations of skin	0.000	0.993	0.007
Q98.4 Klinefelter's syndrome, unspecified	0.000	0.993	0.007
Q52 Other congenital malformations of female genitalia	0.000	0.993	0.007
H53-H54 Visual disturbances and blindness	0.007	0.993	0.000
C67.4 Posterior wall of bladder	0.007	0.993	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.993	0.007
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.993	0.007
Q51.6 Embryonic cyst of cervix	0.000	0.993	0.007
Q51.5 Agenesis and aplasia of cervix	0.000	0.993	0.007
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.993	0.007
Q51.0 Agenesis and aplasia of uterus	0.000	0.993	0.007
C67.0 Trigone of bladder	0.007	0.993	0.000
Q39 Congenital malformations of oesophagus	0.000	0.993	0.007
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.993	0.007
Z58.7 Exposure to tobacco smoke	0.007	0.993	0.000
Q00-Q07 Congenital malformations of the nervous system	0.000	0.993	0.007
Q44.6 Cystic disease of liver	0.000	0.993	0.007
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.993	0.007
C67.1 Dome of bladder	0.007	0.993	0.000
I07 Rheumatic tricuspid valve diseases	0.007	0.993	0.000
Q51.4 Unicornate uterus	0.000	0.993	0.007
Q99 Other chromosome abnormalities, not elsewhere classified	0.000	0.993	0.007
Z56.3 Stressful work schedule	0.007	0.993	0.000
Q96.9 Turner's syndrome, unspecified	0.000	0.993	0.007
H53 Visual disturbances	0.007	0.993	0.000
Q54.9 Hypospadias, unspecified	0.000	0.993	0.007
Z61.9 Negative life events in childhood, unspecified	0.007	0.993	0.000
Z61.8 Other negative life events in childhood	0.007	0.993	0.000
Z61.7 Personal frightening experience in childhood	0.007	0.993	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.007	0.993	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.007	0.993	0.000
Z61.2 Altered pattern of family relationships in childhood	0.007	0.993	0.000
Z61.1 Removal from home in childhood	0.007	0.993	0.000
Z61.0 Loss of love relationship in childhood	0.007	0.993	0.000
Q53.9 Undescended testicle, unspecified	0.000	0.993	0.007
Q53.2 Undescended testicle, bilateral	0.000	0.993	0.007
Q53.0 Ectopic testis	0.000	0.993	0.007
E10.7 With multiple complications	0.007	0.993	0.000
Q83.8 Other congenital malformations of breast	0.000	0.993	0.007
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.993	0.007
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.993	0.007
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.993	0.007
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.993	0.007
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.993	0.007
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.993	0.007
E10.8 With unspecified complications	0.007	0.993	0.000
Q34 Other congenital malformations of respiratory system	0.000	0.993	0.006
Q33 Congenital malformations of lung	0.000	0.993	0.006
Q32 Congenital malformations of trachea and bronchus	0.000	0.993	0.006
Q31 Congenital malformations of larynx	0.000	0.993	0.006
Q30 Congenital malformations of nose	0.000	0.993	0.006
Z65.8 Other specified problems related to psychosocial circumstances	0.006	0.993	0.000
E10.6 With other specified complications	0.007	0.993	0.000
E10.1 With ketoacidosis	0.007	0.993	0.000
Z61.6 Problems related to alleged physical abuse of child	0.006	0.993	0.000
H26.2 Complicated cataract	0.007	0.993	0.000
Z63.5 Disruption of family by separation and divorce	0.006	0.993	0.000
Z65.9 Problem related to unspecified psychosocial circumstances	0.006	0.993	0.000
Z65.5 Exposure to disaster, war and other hostilities	0.006	0.993	0.000
Z65.4 Victim of crime and terrorism	0.006	0.993	0.000
Z65.3 Problems related to other legal circumstances	0.006	0.993	0.000
Z65.2 Problems related to release from prison	0.006	0.993	0.000
Z65.1 Imprisonment and other incarceration	0.006	0.993	0.000
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.006	0.993	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.000	0.993	0.006
Q41 Congenital absence, atresia and stenosis of small intestine	0.000	0.993	0.006
Z64.4 Discord with counsellors	0.006	0.993	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.006	0.993	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.006	0.993	0.000
Z64.1 Problems related to multiparity	0.006	0.993	0.000
Z64.0 Problems related to unwanted pregnancy	0.006	0.993	0.000
Z55.9 Problems relating to education and literacy, unspecified	0.006	0.993	0.000
Z55.8 Other problems relating to education and literacy	0.006	0.993	0.000
Z55.4 Educational maladjustment and discord with teachers and classmates	0.006	0.993	0.000
Z55.3 Underachievement in school	0.006	0.993	0.000
Z55.2 Failed examinations	0.006	0.993	0.000
Z55.1 Schooling unavailable and unattainable	0.006	0.993	0.000
Z55.0 Illiteracy and low-level literacy	0.006	0.993	0.000
Z62.9 Problem related to upbringing, unspecified	0.006	0.993	0.000
Z62.8 Other specified problems related to upbringing	0.006	0.993	0.000
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.006	0.993	0.000
Z62.5 Other problems related to neglect in upbringing	0.006	0.993	0.000
Z62.4 Emotional neglect of child	0.006	0.993	0.000
Z62.3 Hostility towards and scapegoating of child	0.006	0.993	0.000
Z62.2 Institutional upbringing	0.006	0.993	0.000
Z62.1 Parental overprotection	0.006	0.993	0.000
Z62.0 Inadequate parental supervision and control	0.006	0.993	0.000
C67.7 Urachus	0.006	0.994	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.000	0.994	0.006
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.000	0.994	0.006
Q98.7 Male with sex chromosome mosaicism	0.000	0.994	0.006
Q98.6 Male with structurally abnormal sex chromosome	0.000	0.994	0.006
Q98.5 Karyotype 47,XYY	0.000	0.994	0.006
Q98.3 Other male with 46,XX karyotype	0.000	0.994	0.006
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.000	0.994	0.006
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.000	0.994	0.006
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.000	0.994	0.006
Q89.9 Congenital malformation, unspecified	0.000	0.994	0.006
Q89.8 Other specified congenital malformations	0.000	0.994	0.006
Q89.7 Multiple congenital malformations, not elsewhere classified	0.000	0.994	0.006
Q89.4 Conjoined twins	0.000	0.994	0.006
Q89.1 Congenital malformations of adrenal gland	0.000	0.994	0.006
Q89.0 Congenital malformations of spleen	0.000	0.994	0.006
Z58.9 Problem related to physical environment, unspecified	0.006	0.994	0.000
Z58.6 Inadequate drinking-water supply	0.006	0.994	0.000
Z58.4 Exposure to radiation	0.006	0.994	0.000
Z58.3 Exposure to soil pollution	0.006	0.994	0.000
Z58.2 Exposure to water pollution	0.006	0.994	0.000
Z58.0 Exposure to noise	0.006	0.994	0.000
N93.0 Postcoital and contact bleeding	0.006	0.994	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.994	0.006
Q82.2 Mastocytosis	0.000	0.994	0.006
Q96.8 Other variants of Turner's syndrome	0.000	0.994	0.006
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.000	0.994	0.006
Q96.3 Mosaicism, 45,X/46,XX or XY	0.000	0.994	0.006
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.000	0.994	0.006
Q96.1 Karyotype 46,X iso (Xq)	0.000	0.994	0.006
Q96.0 Karyotype 45,X	0.000	0.994	0.006
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.994	0.006
Q45 Other congenital malformations of digestive system	0.000	0.994	0.006
S27 Injury of other and unspecified intrathoracic organs	0.000	0.994	0.006
Q82.9 Congenital malformation of skin, unspecified	0.000	0.994	0.006
Q82.4 Ectodermal dysplasia (anhidrotic)	0.000	0.994	0.006
Q82.3 Incontinentia pigmenti	0.000	0.994	0.006
Q82.1 Xeroderma pigmentosum	0.000	0.994	0.006
Q54.1 Hypospadias, penile	0.000	0.994	0.006
Z58.8 Other problems related to physical environment	0.006	0.994	0.000
E28.3 Primary ovarian failure	0.000	0.994	0.006
Q55.6 Other congenital malformations of penis	0.000	0.994	0.006
Q36 Cleft lip	0.000	0.994	0.006
S27.1 Traumatic haemothorax	0.000	0.994	0.006
Q82.5 Congenital nonneoplastic naevus	0.000	0.994	0.006
C67.5 Bladder neck	0.006	0.994	0.000
Q54.8 Other hypospadias	0.000	0.994	0.006
Q54.4 Congenital chordee	0.000	0.994	0.006
Q54.3 Hypospadias, perineal	0.000	0.994	0.006
Q54.2 Hypospadias, penoscrotal	0.000	0.994	0.006
Q35 Cleft palate	0.000	0.994	0.006
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.994	0.006
Q39.6 Diverticulum of oesophagus	0.000	0.994	0.006
Q56.4 Indeterminate sex, unspecified	0.000	0.994	0.006
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.994	0.006
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.994	0.006
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.994	0.006
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.994	0.006
Z58.1 Exposure to air pollution	0.006	0.994	0.000
Q89.3 Situs inversus	0.000	0.994	0.006
Q39.4 Oesophageal web	0.000	0.994	0.006
Q44.7 Other congenital malformations of liver	0.000	0.994	0.006
Q44.5 Other congenital malformations of bile ducts	0.000	0.994	0.006
Q44.4 Choledochal cyst	0.000	0.994	0.006
Q44.3 Congenital stenosis and stricture of bile ducts	0.000	0.994	0.006
Q44.2 Atresia of bile ducts	0.000	0.994	0.006
Q44.1 Other congenital malformations of gallbladder	0.000	0.994	0.006
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.000	0.994	0.006
Q55.9 Congenital malformation of male genital organ, unspecified	0.000	0.994	0.006
Q55.8 Other specified congenital malformations of male genital organs	0.000	0.994	0.006
Q55.5 Congenital absence and aplasia of penis	0.000	0.994	0.006
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.000	0.994	0.006
Q55.3 Atresia of vas deferens	0.000	0.994	0.006
Q55.1 Hypoplasia of testis and scrotum	0.000	0.994	0.006
Q55.0 Absence and aplasia of testis	0.000	0.994	0.006
Q83.9 Congenital malformation of breast, unspecified	0.000	0.994	0.006
Q83.2 Absent nipple	0.000	0.994	0.006
Q83.0 Congenital absence of breast with absent nipple	0.000	0.994	0.006
E10.2 With renal complications	0.006	0.994	0.000
Q80.9 Congenital ichthyosis, unspecified	0.000	0.994	0.006
Q80.8 Other congenital ichthyosis	0.000	0.994	0.006
Q80.4 Harlequin foetus	0.000	0.994	0.006
Q80.3 Congenital bullous ichthyosiform erythroderma	0.000	0.994	0.006
Q80.2 Lamellar ichthyosis	0.000	0.994	0.006
Q80.1 X-linked ichthyosis	0.000	0.994	0.006
Q80.0 Ichthyosis vulgaris	0.000	0.994	0.006
Q81.9 Epidermolysis bullosa, unspecified	0.000	0.994	0.006
Q81.8 Other epidermolysis bullosa	0.000	0.994	0.006
Q81.2 Epidermolysis bullosa dystrophica	0.000	0.994	0.006
Q81.1 Epidermolysis bullosa letalis	0.000	0.994	0.006
Q81.0 Epidermolysis bullosa simplex	0.000	0.994	0.006
Q84.9 Congenital malformation of integument, unspecified	0.000	0.994	0.006
Q84.8 Other specified congenital malformations of integument	0.000	0.994	0.006
Q84.6 Other congenital malformations of nails	0.000	0.994	0.006
Q84.5 Enlarged and hypertrophic nails	0.000	0.994	0.006
Q84.4 Congenital leukonychia	0.000	0.994	0.006
Q84.3 Anonychia	0.000	0.994	0.006
Q84.2 Other congenital malformations of hair	0.000	0.994	0.006
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.000	0.994	0.006
Q84.0 Congenital alopecia	0.000	0.994	0.006
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.000	0.994	0.006
Q86.2 Dysmorphism due to warfarin	0.000	0.994	0.006
Q86.1 Foetal hydantoin syndrome	0.000	0.994	0.006
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.000	0.994	0.006
Q40 Other congenital malformations of upper alimentary tract	0.000	0.994	0.006
Q37 Cleft palate with cleft lip	0.000	0.994	0.006
Q90.2 Trisomy 21, translocation	0.000	0.994	0.005
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.000	0.994	0.005
Q90.0 Trisomy 21, meiotic nondisjunction	0.000	0.994	0.005
Q91.7 Patau's syndrome, unspecified	0.000	0.994	0.005
Q91.6 Trisomy 13, translocation	0.000	0.994	0.005
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.000	0.994	0.005
Q91.4 Trisomy 13, meiotic nondisjunction	0.000	0.994	0.005
Q91.3 Edwards' syndrome, unspecified	0.000	0.994	0.005
Q91.2 Trisomy 18, translocation	0.000	0.994	0.005
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.000	0.994	0.005
Q91.0 Trisomy 18, meiotic nondisjunction	0.000	0.994	0.005
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.000	0.994	0.005
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.000	0.994	0.005
Q92.7 Triploidy and polyploidy	0.000	0.994	0.005
Q92.6 Extra marker chromosomes	0.000	0.994	0.005
Q92.5 Duplications with other complex rearrangements	0.000	0.994	0.005
Q92.4 Duplications seen only at prometaphase	0.000	0.994	0.005
Q92.3 Minor partial trisomy	0.000	0.994	0.005
Q92.2 Major partial trisomy	0.000	0.994	0.005
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.000	0.994	0.005
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.000	0.994	0.005
Q93.9 Deletion from autosomes, unspecified	0.000	0.994	0.005
Q93.8 Other deletions from the autosomes	0.000	0.994	0.005
Q93.7 Deletions with other complex rearrangements	0.000	0.994	0.005
Q93.6 Deletions seen only at prometaphase	0.000	0.994	0.005
Q93.5 Other deletions of part of a chromosome	0.000	0.994	0.005
Q93.4 Deletion of short arm of chromosome 5	0.000	0.994	0.005
Q93.3 Deletion of short arm of chromosome 4	0.000	0.994	0.005
Q93.2 Chromosome replaced with ring or dicentric	0.000	0.994	0.005
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.000	0.994	0.005
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.000	0.994	0.005
Q95.9 Balanced rearrangement and structural marker, unspecified	0.000	0.994	0.005
Q95.8 Other balanced rearrangements and structural markers	0.000	0.994	0.005
Q95.5 Individuals with autosomal fragile site	0.000	0.994	0.005
Q95.4 Individuals with marker heterochromatin	0.000	0.994	0.005
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.000	0.994	0.005
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.000	0.994	0.005
Q95.1 Chromosome inversion in normal individual	0.000	0.994	0.005
Q95.0 Balanced translocation and insertion in normal individual	0.000	0.994	0.005
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.000	0.994	0.005
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.000	0.994	0.005
Q97.3 Female with 46,XY karyotype	0.000	0.994	0.005
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.000	0.994	0.005
Q97.1 Female with more than three X chromosomes	0.000	0.994	0.005
Q97.0 Karyotype 47,XXX	0.000	0.994	0.005
Q17 Other congenital malformations of ear	0.000	0.994	0.006
Q90.9 Down's syndrome, unspecified	0.000	0.994	0.005
Z57.2 Occupational exposure to dust	0.006	0.994	0.000
Z58.5 Exposure to other pollution	0.005	0.994	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.994	0.005
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.994	0.005
Q52.7 Other congenital malformations of vulva	0.000	0.994	0.005
Q52.6 Congenital malformation of clitoris	0.000	0.994	0.005
Q52.4 Other congenital malformations of vagina	0.000	0.994	0.005
Q52.3 Imperforate hymen	0.000	0.994	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations