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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs393544
log Bayes Factor = 13.0948
Chromosome 6   position 32,074,518  (GRCh37) Explore rs393544 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.001 0.999
E10.9 Without complications
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
L40.9 Psoriasis, unspecified
0.000 0.002 0.998
L40 Psoriasis
0.000 0.002 0.998
E10-E14 Diabetes mellitus
0.000 0.003 0.997
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.003 0.997
L40.5 Arthropathic psoriasis
0.000 0.008 0.992
L40-L45 Papulosquamous disorders
0.000 0.022 0.978
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.024 0.976
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.032 0.968
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.035 0.965
L08 Other local infections of skin and subcutaneous tissue
0.000 0.049 0.951
E10.3 With ophthalmic complications
0.000 0.051 0.949
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.061 0.939
E05.9 Thyrotoxicosis, unspecified
0.000 0.062 0.938
L20-L30 Dermatitis and eczema
0.000 0.102 0.898
M06 Other rheumatoid arthritis
0.000 0.112 0.888
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.112 0.888
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.125 0.875
E04 Other non-toxic goitre
0.000 0.128 0.872
E10.1 With ketoacidosis
0.000 0.137 0.863
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.148 0.852
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.151 0.849
L29 Pruritus
0.000 0.156 0.844
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.156 0.844
L03 Cellulitis
0.000 0.161 0.839
E10.5 With peripheral circulatory complications
0.000 0.176 0.824
E06 Thyroiditis
0.000 0.188 0.812
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.190 0.810
E10.4 With neurological complications
0.000 0.194 0.806
L40.0 Psoriasis vulgaris
0.000 0.198 0.802
E04.2 Non-toxic multinodular goitre
0.000 0.201 0.799
M06.0 Seronegative rheumatoid arthritis
0.000 0.218 0.782
E50-E64 Other nutritional deficiencies
0.000 0.221 0.779
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.226 0.774
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.232 0.768
L29.0 Pruritus ani
0.000 0.235 0.765
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.235 0.765
L03.3 Cellulitis of trunk
0.000 0.241 0.759
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.261 0.739
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.264 0.736
L03.1 Cellulitis of other parts of limb
0.000 0.264 0.736
E40-E46 Malnutrition
0.000 0.275 0.725
E13 Other specified diabetes mellitus
0.000 0.282 0.718
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.716
E10.6 With other specified complications
0.000 0.283 0.716
E10.2 With renal complications
0.000 0.283 0.716
E10.0 With coma
0.000 0.283 0.716
L40.8 Other psoriasis
0.000 0.284 0.716
L40.4 Guttate psoriasis
0.000 0.284 0.716
L40.3 Pustulosis palmaris et plantaris
0.000 0.284 0.716
L40.2 Acrodermatitis continua
0.000 0.284 0.716
L40.1 Generalised pustular psoriasis
0.000 0.284 0.716
E12 Malnutrition-related diabetes mellitus
0.000 0.285 0.715
M05-M14 Inflammatory polyarthropathies
0.000 0.288 0.712
L27 Dermatitis due to substances taken internally
0.000 0.290 0.710
L29.2 Pruritus vulvae
0.000 0.292 0.708
L05 Pilonidal cyst
0.000 0.296 0.704
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.297 0.703
L44 Other papulosquamous disorders
0.000 0.299 0.701
L41 Parapsoriasis
0.000 0.299 0.701
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.299 0.701
E05.8 Other thyrotoxicosis
0.000 0.300 0.700
E05.5 Thyroid crisis or storm
0.000 0.300 0.700
E05.4 Thyrotoxicosis factitia
0.000 0.300 0.700
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.300 0.700
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.300 0.700
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.300 0.700
L10-L14 Bullous disorders
0.000 0.306 0.694
L04 Acute lymphadenitis
0.000 0.308 0.692
L01 Impetigo
0.000 0.308 0.692
L00 Staphylococcal scalded skin syndrome
0.000 0.308 0.692
E06.3 Autoimmune thyroiditis
0.000 0.309 0.691
L43 Lichen planus
0.000 0.315 0.685
L08.1 Erythrasma
0.000 0.318 0.682
L08.0 Pyoderma
0.000 0.318 0.682
E55 Vitamin D deficiency
0.000 0.330 0.670
E03.8 Other specified hypothyroidism
0.000 0.334 0.666
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.338 0.662
E10.8 With unspecified complications
0.000 0.339 0.661
K90.0 Coeliac disease
0.659 0.341 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.342 0.658
L28 Lichen simplex chronicus and prurigo
0.000 0.348 0.652
E65-E68 Obesity and other hyperalimentation
0.000 0.350 0.650
L25 Unspecified contact dermatitis
0.000 0.356 0.644
L24 Irritant contact dermatitis
0.000 0.356 0.644
L23 Allergic contact dermatitis
0.000 0.356 0.644
L21 Seborrhoeic dermatitis
0.000 0.356 0.644
L26 Exfoliative dermatitis
0.000 0.356 0.644
L22 Diaper [napkin] dermatitis
0.000 0.356 0.644
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.357 0.643
L29.9 Pruritus, unspecified
0.000 0.360 0.640
M06.8 Other specified rheumatoid arthritis
0.000 0.363 0.637
M06.4 Inflammatory polyarthropathy
0.000 0.363 0.637
M06.2 Rheumatoid bursitis
0.000 0.363 0.637
M06.1 Adult-onset Still's disease
0.000 0.363 0.637
L20 Atopic dermatitis
0.000 0.367 0.633
E04.8 Other specified non-toxic goitre
0.000 0.375 0.625
E04.0 Non-toxic diffuse goitre
0.000 0.375 0.625
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.377 0.623
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.381 0.619
E04.9 Non-toxic goitre, unspecified
0.000 0.381 0.619
M06.3 Rheumatoid nodule
0.000 0.384 0.615
M07 Psoriatic and enteropathic arthropathies
0.000 0.386 0.614
# Top node
0.000 0.393 0.607
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.394 0.606
L29.8 Other pruritus
0.000 0.395 0.605
L29.3 Anogenital pruritus, unspecified
0.000 0.395 0.605
L29.1 Pruritus scroti
0.000 0.395 0.605
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.395 0.605
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.396 0.604
M05 Seropositive rheumatoid arthritis
0.000 0.398 0.602
L42 Pityriasis rosea
0.000 0.398 0.601
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.403 0.597
D60-D64 Aplastic and other anaemias
0.000 0.405 0.595
E55.9 Vitamin D deficiency, unspecified
0.000 0.409 0.591
L30 Other dermatitis
0.000 0.411 0.589
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.412 0.588
Chapter X Diseases of the respiratory system
0.000 0.417 0.583
E06.5 Other chronic thyroiditis
0.000 0.418 0.582
E06.4 Drug-induced thyroiditis
0.000 0.418 0.582
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.418 0.582
E06.1 Subacute thyroiditis
0.000 0.418 0.582
E06.0 Acute thyroiditis
0.000 0.418 0.582
D64 Other anaemias
0.000 0.418 0.582
L03.2 Cellulitis of face
0.000 0.419 0.581
L50-L54 Urticaria and erythema
0.000 0.422 0.578
D64.9 Anaemia, unspecified
0.000 0.427 0.573
E04.1 Non-toxic single thyroid nodule
0.000 0.431 0.569
L03.8 Cellulitis of other sites
0.000 0.431 0.568
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.435 0.564
E14 Unspecified diabetes mellitus
0.000 0.437 0.563
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.439 0.561
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.439 0.561
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.439 0.561
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.439 0.561
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.439 0.561
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.439 0.561
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.439 0.561
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.439 0.561
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.440 0.560
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.441 0.559
E63 Other nutritional deficiencies
0.000 0.441 0.559
E56 Other vitamin deficiencies
0.000 0.441 0.559
E51 Thiamine deficiency
0.000 0.441 0.559
E50 Vitamin A deficiency
0.000 0.441 0.559
E60 Dietary zinc deficiency
0.000 0.441 0.559
E59 Dietary selenium deficiency
0.000 0.441 0.559
E58 Dietary calcium deficiency
0.000 0.441 0.559
E54 Ascorbic acid deficiency
0.000 0.441 0.559
E52 Niacin deficiency [pellagra]
0.000 0.441 0.559
E20-E35 Disorders of other endocrine glands
0.000 0.443 0.557
E06.9 Thyroiditis, unspecified
0.000 0.445 0.555
E07 Other disorders of thyroid
0.000 0.450 0.550
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.452 0.548
L58 Radiodermatitis
0.000 0.452 0.548
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.452 0.548
L55 Sunburn
0.000 0.452 0.548
E53 Deficiency of other B group vitamins
0.000 0.454 0.546
M07.3 Other psoriatic arthropathies
0.000 0.456 0.544
L05.0 Pilonidal cyst with abscess
0.000 0.458 0.542
Chapter I Certain infectious and parasitic diseases
0.000 0.468 0.532
D80-D89 Certain disorders involving the immune mechanism
0.000 0.468 0.532
E46 Unspecified protein-energy malnutrition
0.000 0.470 0.530
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.472 0.528
M14 Arthropathies in other diseases classified elsewhere
0.000 0.477 0.523
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.477 0.523
J09-J18 Influenza and pneumonia
0.000 0.478 0.522
J40-J47 Chronic lower respiratory diseases
0.000 0.479 0.521
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.480 0.520
E45 Retarded development following protein-energy malnutrition
0.000 0.480 0.520
E43 Unspecified severe protein-energy malnutrition
0.000 0.480 0.520
E42 Marasmic kwashiorkor
0.000 0.480 0.520
E41 Nutritional marasmus
0.000 0.480 0.520
E40 Kwashiorkor
0.000 0.480 0.520
L03.0 Cellulitis of finger and toe
0.000 0.481 0.519
E13.9 Without complications
0.000 0.483 0.517
E70-E90 Metabolic disorders
0.000 0.483 0.517
D61 Other aplastic anaemias
0.000 0.483 0.517
M11 Other crystal arthropathies
0.000 0.484 0.516
E13.8 With unspecified complications
0.000 0.485 0.515
E13.7 With multiple complications
0.000 0.485 0.515
E13.6 With other specified complications
0.000 0.485 0.515
E13.5 With peripheral circulatory complications
0.000 0.485 0.515
E13.4 With neurological complications
0.000 0.485 0.515
E13.3 With ophthalmic complications
0.000 0.485 0.515
E13.2 With renal complications
0.000 0.485 0.515
E13.1 With ketoacidosis
0.000 0.485 0.515
E13.0 With coma
0.000 0.485 0.515
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
J20-J22 Other acute lower respiratory infections
0.000 0.486 0.514
E12.9 Without complications
0.000 0.487 0.513
E12.8 With unspecified complications
0.000 0.487 0.513
E12.7 With multiple complications
0.000 0.487 0.513
E12.6 With other specified complications
0.000 0.487 0.513
E12.5 With peripheral circulatory complications
0.000 0.487 0.513
E12.4 With neurological complications
0.000 0.487 0.513
E12.3 With ophthalmic complications
0.000 0.487 0.513
E12.2 With renal complications
0.000 0.487 0.513
E12.1 With ketoacidosis
0.000 0.487 0.513
E12.0 With coma
0.000 0.487 0.513
M12 Other specific arthropathies
0.000 0.489 0.511
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.489 0.511
M08 Juvenile arthritis
0.000 0.489 0.511
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.491 0.509
L27.8 Dermatitis due to other substances taken internally
0.000 0.491 0.509
L27.2 Dermatitis due to ingested food
0.000 0.491 0.509
B25-B34 Other viral diseases
0.000 0.492 0.508
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.493 0.507
L41.9 Parapsoriasis, unspecified
0.000 0.497 0.503
L41.8 Other parapsoriasis
0.000 0.497 0.503
L41.5 Retiform parapsoriasis
0.000 0.497 0.503
L41.4 Large plaque parapsoriasis
0.000 0.497 0.503
L41.3 Small plaque parapsoriasis
0.000 0.497 0.503
L41.2 Lymphomatoid papulosis
0.000 0.497 0.503
L41.1 Pityriasis lichenoides chronica
0.000 0.497 0.503
L41.0 Pityriasis lichenoides et varioliformis acuta
0.000 0.497 0.503
L44.9 Papulosquamous disorder, unspecified
0.000 0.497 0.503
L44.8 Other specified papulosquamous disorders
0.000 0.497 0.503
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.000 0.497 0.503
L44.3 Lichen ruber moniliformis
0.000 0.497 0.503
L44.2 Lichen striatus
0.000 0.497 0.503
L44.1 Lichen nitidus
0.000 0.497 0.503
L44.0 Pityriasis rubra pilaris
0.000 0.497 0.503
J18 Pneumonia, organism unspecified
0.000 0.502 0.498
L13 Other bullous disorders
0.000 0.502 0.497
L12 Pemphigoid
0.000 0.502 0.497
L11 Other acantholytic disorders
0.000 0.502 0.497
L10 Pemphigus
0.000 0.502 0.497
L14 Bullous disorders in diseases classified elsewhere
0.000 0.502 0.497
J47 Bronchiectasis
0.000 0.504 0.496
L01.1 Impetiginisation of other dermatoses
0.000 0.504 0.496
L01.0 Impetigo [any organism] [any site]
0.000 0.504 0.496
L04.9 Acute lymphadenitis, unspecified
0.000 0.504 0.496
L04.8 Acute lymphadenitis of other sites
0.000 0.504 0.496
L04.3 Acute lymphadenitis of lower limb
0.000 0.504 0.496
L04.2 Acute lymphadenitis of upper limb
0.000 0.504 0.496
L04.1 Acute lymphadenitis of trunk
0.000 0.504 0.496
L04.0 Acute lymphadenitis of face, head and neck
0.000 0.504 0.496
E27 Other disorders of adrenal gland
0.000 0.505 0.495
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.506 0.494
L43.8 Other lichen planus
0.000 0.509 0.491
L43.3 Subacute (active) lichen planus
0.000 0.509 0.491
L43.2 Lichenoid drug reaction
0.000 0.509 0.491
L43.1 Bullous lichen planus
0.000 0.509 0.491
L43.0 Hypertrophic lichen planus
0.000 0.509 0.491
J18.1 Lobar pneumonia, unspecified
0.000 0.510 0.490
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.512 0.488
E65 Localised adiposity
0.000 0.512 0.488
B34 Viral infection of unspecified site
0.000 0.518 0.482
E61 Deficiency of other nutrient elements
0.000 0.519 0.481
E55.0 Rickets, active
0.000 0.520 0.480
D50-D53 Nutritional anaemias
0.000 0.523 0.477
L28.0 Lichen simplex chronicus
0.000 0.524 0.475
L43.9 Lichen planus, unspecified
0.000 0.524 0.475
D86 Sarcoidosis
0.000 0.525 0.475
L05.9 Pilonidal cyst without abscess
0.000 0.526 0.474
J81 Pulmonary oedema
0.000 0.528 0.472
L28.2 Other prurigo
0.000 0.532 0.468
L28.1 Prurigo nodularis
0.000 0.532 0.468
L03.9 Cellulitis, unspecified
0.000 0.533 0.467
J44 Other chronic obstructive pulmonary disease
0.000 0.533 0.467
E67 Other hyperalimentation
0.000 0.534 0.466
E68 Sequelae of hyperalimentation
0.000 0.534 0.466
J22 Unspecified acute lower respiratory infection
0.000 0.535 0.465
J30-J39 Other diseases of upper respiratory tract
0.000 0.536 0.464
B34.9 Viral infection, unspecified
0.000 0.537 0.463
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.538 0.462
L21.8 Other seborrhoeic dermatitis
0.000 0.538 0.462
L21.1 Seborrhoeic infantile dermatitis
0.000 0.538 0.462
L21.0 Seborrhoea capitis
0.000 0.538 0.462
L23.9 Allergic contact dermatitis, unspecified cause
0.000 0.538 0.462
L23.8 Allergic contact dermatitis due to other agents
0.000 0.538 0.462
L23.7 Allergic contact dermatitis due to plants, except food
0.000 0.538 0.462
L23.6 Allergic contact dermatitis due to food in contact with the skin
0.000 0.538 0.462
L23.5 Allergic contact dermatitis due to other chemical products
0.000 0.538 0.462
L23.4 Allergic contact dermatitis due to dyes
0.000 0.538 0.462
L23.3 Allergic contact dermatitis due to drugs in contact with the skin
0.000 0.538 0.462
L23.2 Allergic contact dermatitis due to cosmetics
0.000 0.538 0.462
L23.1 Allergic contact dermatitis due to adhesives
0.000 0.538 0.462
L23.0 Allergic contact dermatitis due to metals
0.000 0.538 0.462
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.538 0.462
L24.8 Irritant contact dermatitis due to other agents
0.000 0.538 0.462
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.538 0.462
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.538 0.462
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.538 0.462
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.538 0.462
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.538 0.462
L24.2 Irritant contact dermatitis due to solvents
0.000 0.538 0.462
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.538 0.462
L24.0 Irritant contact dermatitis due to detergents
0.000 0.538 0.462
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.538 0.462
L25.8 Unspecified contact dermatitis due to other agents
0.000 0.538 0.462
L25.5 Unspecified contact dermatitis due to plants, except food
0.000 0.538 0.462
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.000 0.538 0.462
L25.3 Unspecified contact dermatitis due to other chemical products
0.000 0.538 0.462
L25.2 Unspecified contact dermatitis due to dyes
0.000 0.538 0.462
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin
0.000 0.538 0.462
L25.0 Unspecified contact dermatitis due to cosmetics
0.000 0.538 0.462
D55-D59 Haemolytic anaemias
0.000 0.538 0.461
D61.9 Aplastic anaemia, unspecified
0.000 0.539 0.461
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.541 0.459
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.543 0.456
M06.18 Adult-onset Still's disease (Other)
0.000 0.543 0.456
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.543 0.456
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.543 0.456
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.543 0.456
M06.14 Adult-onset Still's disease (Hand)
0.000 0.543 0.456
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.543 0.456
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.543 0.456
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.543 0.456
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.543 0.456
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.543 0.456
M06.28 Rheumatoid bursitis (Other)
0.000 0.543 0.456
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.543 0.456
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.543 0.456
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.543 0.456
M06.24 Rheumatoid bursitis (Hand)
0.000 0.543 0.456
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.543 0.456
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.543 0.456
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.543 0.456
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.543 0.456
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.543 0.456
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.543 0.456
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.543 0.456
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.543 0.456
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.543 0.456
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.543 0.456
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.543 0.456
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.543 0.456
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.543 0.456
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.543 0.456
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.543 0.456
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.543 0.456
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.543 0.456
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.543 0.456
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.543 0.456
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.543 0.456
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.543 0.456
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.543 0.456
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.543 0.456
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.543 0.456
L57.0 Actinic keratosis
0.000 0.544 0.456
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.545 0.455
L20.8 Other atopic dermatitis
0.000 0.546 0.454
L20.0 Besnier's prurigo
0.000 0.546 0.454
J80 Adult respiratory distress syndrome
0.000 0.546 0.454
E86 Volume depletion
0.000 0.552 0.448
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.553 0.447
E15 Nondiabetic hypoglycaemic coma
0.000 0.553 0.447
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.556 0.444
L57.5 Actinic granuloma
0.000 0.556 0.444
L57.4 Cutis laxa senilis
0.000 0.556 0.444
L57.3 Poikiloderma of Civatte
0.000 0.556 0.444
L57.2 Cutis rhomboidalis nuchae
0.000 0.556 0.444
L57.1 Actinic reticuloid
0.000 0.556 0.444
L20.9 Atopic dermatitis, unspecified
0.000 0.558 0.442
L30.8 Other specified dermatitis
0.000 0.558 0.442
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.559 0.441
M06.38 Rheumatoid nodule (Other)
0.000 0.559 0.441
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.559 0.441
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.559 0.441
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.559 0.441
M06.33 Rheumatoid nodule (Forearm)
0.000 0.559 0.441
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.559 0.441
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.559 0.441
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.559 0.441
M07.6 Other enteropathic arthropathies
0.000 0.560 0.440
M07.5 Arthropathy in ulcerative colitis
0.000 0.560 0.440
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.560 0.440
M07.2 Psoriatic spondylitis
0.000 0.560 0.440
M07.1 Arthritis mutilans
0.000 0.560 0.440
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.560 0.440
B35-B49 Mycoses
0.000 0.563 0.437
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.000 0.564 0.435
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.565 0.435
D62 Acute posthaemorrhagic anaemia
0.000 0.566 0.434
M05.8 Other seropositive rheumatoid arthritis
0.000 0.568 0.432
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.568 0.432
M05.2 Rheumatoid vasculitis
0.000 0.568 0.432
M05.1 Rheumatoid lung disease
0.000 0.568 0.432
M05.0 Felty's syndrome
0.000 0.568 0.432
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.570 0.430
E11 Non-insulin-dependent diabetes mellitus
0.000 0.571 0.429
J33 Nasal polyp
0.000 0.571 0.429
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.573 0.427
E27.1 Primary adrenocortical insufficiency
0.000 0.573 0.427
J35 Chronic diseases of tonsils and adenoids
0.000 0.574 0.426
E89.0 Postprocedural hypothyroidism
0.000 0.574 0.425
J10 Influenza due to identified influenza virus
0.000 0.577 0.423
L30.5 Pityriasis alba
0.000 0.578 0.422
L30.4 Erythema intertrigo
0.000 0.578 0.422
L30.3 Infective dermatitis
0.000 0.578 0.422
L30.2 Cutaneous autosensitisation
0.000 0.578 0.422
L30.1 Dyshidrosis [pompholyx]
0.000 0.578 0.422
L30.0 Nummular dermatitis
0.000 0.578 0.422
M06.34 Rheumatoid nodule (Hand)
0.000 0.580 0.420
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.581 0.419
M91-M94 Chondropathies
0.000 0.581 0.419
D64.8 Other specified anaemias
0.000 0.583 0.417
D64.4 Congenital dyserythropoietic anaemia
0.000 0.583 0.417
D64.3 Other sideroblastic anaemias
0.000 0.583 0.417
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.583 0.417
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.583 0.417
D64.0 Hereditary sideroblastic anaemia
0.000 0.583 0.417
M80-M85 Disorders of bone density and structure
0.000 0.583 0.417
M86-M90 Other osteopathies
0.000 0.583 0.417
E28 Ovarian dysfunction
0.000 0.583 0.416
L54 Erythema in diseases classified elsewhere
0.000 0.585 0.414
L51 Erythema multiforme
0.000 0.585 0.414
J40 Bronchitis, not specified as acute or chronic
0.000 0.586 0.414
A30-A49 Other bacterial diseases
0.000 0.586 0.414
B25 Cytomegaloviral disease
0.000 0.589 0.411
L60-L75 Disorders of skin appendages
0.000 0.589 0.411
J35.0 Chronic tonsillitis
0.000 0.589 0.411
L50 Urticaria
0.000 0.593 0.407
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.593 0.407
D86.9 Sarcoidosis, unspecified
0.000 0.594 0.406
E14.8 With unspecified complications
0.000 0.596 0.403
E14.7 With multiple complications
0.000 0.596 0.403
E14.6 With other specified complications
0.000 0.596 0.403
E14.5 With peripheral circulatory complications
0.000 0.596 0.403
E14.4 With neurological complications
0.000 0.596 0.403
E14.2 Withrenal complications
0.000 0.596 0.403
E14.1 With ketoacidosis
0.000 0.596 0.403
E14.0 With coma
0.000 0.596 0.403
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.596 0.404
M60-M63 Disorders of muscles
0.000 0.597 0.403
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.597 0.403
E14.3 With ophthalmic complications
0.000 0.597 0.403
E50.9 Vitamin A deficiency, unspecified
0.000 0.599 0.401
E50.8 Other manifestations of vitamin A deficiency
0.000 0.599 0.401
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.599 0.401
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.599 0.401
E50.5 Vitamin A deficiency with night blindness
0.000 0.599 0.401
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.599 0.401
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.599 0.401
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.599 0.401
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.599 0.401
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.599 0.401
E51.9 Thiamine deficiency, unspecified
0.000 0.599 0.401
E51.8 Other manifestations of thiamine deficiency
0.000 0.599 0.401
E51.2 Wernicke's encephalopathy
0.000 0.599 0.401
E51.1 Beriberi
0.000 0.599 0.401
E56.9 Vitamin deficiency, unspecified
0.000 0.599 0.401
E56.8 Deficiency of other vitamins
0.000 0.599 0.401
E56.1 Deficiency of vitamin K
0.000 0.599 0.401
E56.0 Deficiency of vitamin E
0.000 0.599 0.401
E63.9 Nutritional deficiency, unspecified
0.000 0.599 0.401
E63.8 Other specified nutritional deficiencies
0.000 0.599 0.401
E63.1 Imbalance of constituents of food intake
0.000 0.599 0.401
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.599 0.401
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.599 0.401
E64.8 Sequelae of other nutritional deficiencies
0.000 0.599 0.401
E64.3 Sequelae of rickets
0.000 0.599 0.401
E64.2 Sequelae of vitamin C deficiency
0.000 0.599 0.401
E64.1 Sequelae of vitamin A deficiency
0.000 0.599 0.401
E64.0 Sequelae of protein-energy malnutrition
0.000 0.599 0.401
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.600 0.400
J32 Chronic sinusitis
0.000 0.600 0.400
E88 Other metabolic disorders
0.000 0.600 0.400
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.600 0.399
E32 Diseases of thymus
0.000 0.600 0.399
E31 Polyglandular dysfunction
0.000 0.600 0.399
E30 Disorders of puberty, not elsewhere classified
0.000 0.600 0.399
E25 Adrenogenital disorders
0.000 0.600 0.399
E20 Hypoparathyroidism
0.000 0.600 0.399
A80-A89 Viral infections of the central nervous system
0.000 0.601 0.399
M00-M03 Infectious arthropathies
0.000 0.601 0.399
B65-B83 Helminthiases
0.000 0.602 0.398
D86.0 Sarcoidosis of lung
0.000 0.603 0.397
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.604 0.396
D50 Iron deficiency anaemia
0.000 0.605 0.395
E07.8 Other specified disorders of thyroid
0.000 0.605 0.394
E07.1 Dyshormogenetic goitre
0.000 0.605 0.394
E07.0 Hypersecretion of calcitonin
0.000 0.605 0.394
M10 Gout
0.000 0.605 0.395

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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