TreeWAS – Variant ID: rs39861

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M19.93 Arthrosis, unspecified (Forearm)	0.039	0.961	0.000
S62.5 Fracture of thumb	0.026	0.974	0.000
S62 Fracture at wrist and hand level	0.026	0.974	0.000
S62.51 Fracture of thumb (open)	0.025	0.975	0.000
S62.50 Fracture of thumb (closed)	0.023	0.977	0.000
S62.6 Fracture of other finger	0.023	0.977	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.023	0.977	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.023	0.977	0.000
S62.60 Fracture of other finger (closed)	0.022	0.978	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.022	0.978	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.978	0.022
N41.1 Chronic prostatitis	0.000	0.979	0.021
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.021	0.979	0.000
S60-S69 Injuries to the wrist and hand	0.021	0.979	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.021	0.979	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.021	0.979	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.021	0.979	0.000
S62.3 Fracture of other metacarpal bone	0.021	0.979	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.980	0.020
S62.1 Fracture of other carpal bone(s)	0.020	0.980	0.000
T42.4 Benzodiazepines	0.000	0.980	0.020
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.020	0.980	0.000
G93 Other disorders of brain	0.020	0.980	0.000
G90-G99 Other disorders of the nervous system	0.019	0.981	0.000
S62.2 Fracture of first metacarpal bone	0.019	0.981	0.000
G93.0 Cerebral cysts	0.019	0.981	0.000
G96 Other disorders of central nervous system	0.019	0.981	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.019	0.981	0.000
G93.6 Cerebral oedema	0.018	0.982	0.000
G96.0 Cerebrospinal fluid leak	0.018	0.982	0.000
G93.2 Benign intracranial hypertension	0.018	0.982	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.018	0.982	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.018	0.982	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.018	0.982	0.000
S69 Other and unspecified injuries of wrist and hand	0.018	0.982	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.018	0.982	0.000
S62.31 Fracture of other metacarpal bone (open)	0.017	0.983	0.000
S64 Injury of nerves at wrist and hand level	0.017	0.983	0.000
T42.1 Iminostilbenes	0.000	0.983	0.017
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.983	0.017
S67 Crushing injury of wrist and hand	0.017	0.983	0.000
S62.4 Multiple fractures of metacarpal bones	0.017	0.983	0.000
G95 Other diseases of spinal cord	0.017	0.983	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.016	0.983	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.016	0.983	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.016	0.983	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.016	0.983	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.016	0.984	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.016	0.984	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.016	0.984	0.000
S60 Superficial injury of wrist and hand	0.016	0.984	0.000
G95.0 Syringomyelia and syringobulbia	0.016	0.984	0.000
S64.4 Injury of digital nerve of other finger	0.016	0.984	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.015	0.985	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.015	0.985	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.015	0.985	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.985	0.015
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.985	0.015
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.985	0.015
T42.3 Barbiturates	0.000	0.985	0.015
T42.2 Succinimides and oxazolidinediones	0.000	0.985	0.015
S62.7 Multiple fractures of fingers	0.015	0.985	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.015	0.985	0.000
S65 Injury of blood vessels at wrist and hand level	0.015	0.985	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.015	0.985	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.015	0.985	0.000
T42.0 Hydantoin derivatives	0.000	0.986	0.014
G94 Other disorders of brain in diseases classified elsewhere	0.014	0.986	0.000
G93.7 Reye's syndrome	0.014	0.986	0.000
S69.7 Multiple injuries of wrist and hand	0.014	0.986	0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.014	0.986	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.014	0.986	0.000
S60.2 Contusion of other parts of wrist and hand	0.014	0.986	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.014	0.986	0.000
G92 Toxic encephalopathy	0.014	0.986	0.000
S62.21 Fracture of first metacarpal bone (open)	0.014	0.986	0.000
S69.9 Unspecified injury of wrist and hand	0.014	0.986	0.000
G96.9 Disorder of central nervous system, unspecified	0.014	0.986	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.014	0.986	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.014	0.986	0.000
G95.1 Vascular myelopathies	0.014	0.986	0.000
S69.8 Other specified injuries of wrist and hand	0.014	0.986	0.000
G96.8 Other specified disorders of central nervous system	0.013	0.986	0.000
S68 Traumatic amputation of wrist and hand	0.013	0.987	0.000
G93.5 Compression of brain	0.012	0.987	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.013	0.987	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.012	0.987	0.000
S64.8 Injury of other nerves at wrist and hand level	0.012	0.987	0.000
G93.8 Other specified disorders of brain	0.013	0.987	0.000
S64.1 Injury of median nerve at wrist and hand level	0.012	0.988	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.012	0.988	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.012	0.988	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.012	0.988	0.000
S62.61 Fracture of other finger (open)	0.012	0.988	0.000
G90 Disorders of autonomic nervous system	0.012	0.988	0.000
S63.1 Dislocation finger	0.012	0.988	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.012	0.988	0.000
S63.2 Multiple dislocations of fingers	0.012	0.988	0.000
S65.1 Injury of radial artery at wrist and hand level	0.012	0.988	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.012	0.988	0.000
G95.8 Other specified diseases of spinal cord	0.012	0.988	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.012	0.988	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.012	0.988	0.000
I71.0 Dissection of aorta [any part]	0.012	0.988	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.012	0.988	0.000
G94.1 Hydrocephalus in neoplastic disease	0.012	0.988	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.011	0.988	0.000
G93.9 Disorder of brain, unspecified	0.011	0.989	0.000
I71 Aortic aneurysm and dissection	0.011	0.989	0.000
S60.1 Contusion of finger(s) with damage to nail	0.011	0.989	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.011	0.989	0.000
G93.3 Postviral fatigue syndrome	0.011	0.989	0.000
S63.0 Dislocation of wrist	0.011	0.989	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.011	0.989	0.000
S65.8 Injury of other blood vessels at wrist and hand level	0.011	0.989	0.000
S65.7 Injury of multiple blood vessels at wrist and hand level	0.011	0.989	0.000
S65.4 Injury of blood vessel(s) of thumb	0.011	0.989	0.000
S65.3 Injury of deep palmar arch	0.011	0.989	0.000
S65.2 Injury of superficial palmar arch	0.011	0.989	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.010	0.989	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.010	0.989	0.000
S63.5 Sprain and strain of wrist	0.010	0.989	0.000
G95.9 Disease of spinal cord, unspecified	0.010	0.989	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.010	0.990	0.000
S63.6 Sprain and strain of finger(s)	0.010	0.990	0.000
S64.3 Injury of digital nerve of thumb	0.010	0.990	0.000
S62.70 Multiple fractures of fingers (closed)	0.010	0.990	0.000
G93.4 Encephalopathy, unspecified	0.010	0.990	0.000
G95.2 Cord compression, unspecified	0.010	0.990	0.000
S65.5 Injury of blood vessel(s) of other finger	0.010	0.990	0.000
S60.0 Contusion of finger(s) without damage to nail	0.010	0.990	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.010	0.990	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.010	0.990	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.009	0.990	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.990	0.010
S60.8 Other superficial injuries of wrist and hand	0.009	0.990	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.009	0.990	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.009	0.991	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.009	0.991	0.000
S68.4 Traumatic amputation of hand at wrist level	0.009	0.991	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.009	0.991	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.009	0.991	0.000
G90.8 Other disorders of autonomic nervous system	0.009	0.991	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.009	0.991	0.000
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.009	0.991	0.000
G90.4 Autonomic dysreflexia	0.009	0.991	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.009	0.991	0.000
G90.2 Horner's syndrome	0.009	0.991	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.009	0.991	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.009	0.991	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.008	0.991	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.009	0.991	0.000
S62.71 Multiple fractures of fingers (open)	0.008	0.992	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.008	0.992	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.008	0.992	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.008	0.992	0.000
G90.3 Multisystem degeneration	0.008	0.992	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.008	0.992	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.008	0.992	0.000
H61.2 Impacted cerumen	0.000	0.992	0.008
I71.3 Abdominal aortic aneurysm, ruptured	0.008	0.992	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.007	0.992	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.993	0.007
Y54.3 Benzothiadiazine derivatives	0.007	0.993	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.007	0.993	0.000
D52.9 Folate deficiency anaemia, unspecified	0.007	0.993	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.994	0.006
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.994	0.006
J84.1 Other interstitial pulmonary diseases with fibrosis	0.006	0.994	0.000
G97.8 Other postprocedural disorders of nervous system	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.994	0.006
Y84.8 Other medical procedures	0.000	0.994	0.006
K35.3 Acute appendicitis with localized peritonitis	0.000	0.994	0.006
T50.8 Diagnostic agents	0.000	0.994	0.005
T50.7 Analeptics and opioid receptor antagonists	0.000	0.994	0.005
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.994	0.005
T50.5 Appetite depressants	0.000	0.994	0.005
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.994	0.005
T50.1 Loop [high-ceiling] diuretics	0.000	0.994	0.005
T50.0 Mineralocorticoids and their antagonists	0.000	0.994	0.005
Q24 Other congenital malformations of heart	0.005	0.994	0.000
H50.9 Strabismus, unspecified	0.005	0.995	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.995	0.005
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.995	0.005
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.995	0.005
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.005	0.995	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.995	0.005
Q20-Q28 Congenital malformations of the circulatory system	0.005	0.995	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.995	0.005
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.995	0.005
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.995	0.005
Y54.4 Loop [high-ceiling] diuretics	0.005	0.995	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.995	0.005
T50.4 Drugs affecting uric acid metabolism	0.000	0.995	0.005
Q24.6 Congenital heart block	0.005	0.995	0.000
Y54.7 Agents affecting calcification	0.005	0.995	0.000
C71.2 Temporal lobe	0.005	0.995	0.000
Q21 Congenital malformations of cardiac septa	0.005	0.995	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.005	0.995	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.995	0.005
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
Y54.8 Agents affecting uric acid metabolism	0.005	0.995	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.995	0.005
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.995	0.005
O69.3 Labour and delivery complicated by short cord	0.000	0.995	0.005
D52 Folate deficiency anaemia	0.005	0.995	0.000
Q24.0 Dextrocardia	0.005	0.995	0.000
Q24.5 Malformation of coronary vessels	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.995	0.005
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.005	0.995	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.995	0.004
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.995	0.004
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.995	0.004
O69.8 Labour and delivery complicated by other cord complications	0.000	0.995	0.004
Q21.1 Atrial septal defect	0.005	0.995	0.000
X62.9 Unspecified place	0.000	0.995	0.005
Y54.9 Mineral salts, not elsewhere classified	0.004	0.995	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.995	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.995	0.000
Y54.0 Mineralocorticoids	0.004	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.004	0.995	0.000
Y54.5 Other diuretics	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.996	0.004
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.996	0.004
G91 Hydrocephalus	0.004	0.996	0.001
Q28 Other congenital malformations of circulatory system	0.004	0.996	0.000
Q24.4 Congenital subaortic stenosis	0.004	0.996	0.000
Q24.3 Pulmonary infundibular stenosis	0.004	0.996	0.000
Q24.2 Cor triatriatum	0.004	0.996	0.000
Q24.1 Levocardia	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.996	0.004
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.996	0.004
T46.7 Peripheral vasodilators	0.000	0.996	0.004
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.996	0.004
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.996	0.004
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.996	0.004
T47.7 Emetics	0.000	0.996	0.004
T47.6 Antidiarrhoeal drugs	0.000	0.996	0.004
T47.5 Digestants	0.000	0.996	0.004
T47.3 Saline and osmotic laxatives	0.000	0.996	0.004
T47.0 Histamine H(2)-receptor antagonists	0.000	0.996	0.004
Q26 Congenital malformations of great veins	0.004	0.996	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q25.4 Other congenital malformations of aorta	0.004	0.996	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.996	0.004
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.996	0.004
T38.7 Androgens and anabolic congeners	0.000	0.996	0.004
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.996	0.004
T38.5 Other oestrogens and progestogens	0.000	0.996	0.004
T38.4 Oral contraceptives	0.000	0.996	0.004
T38.2 Antithyroid drugs	0.000	0.996	0.004
T38.0 Glucocorticoids and synthetic analogues	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.000	0.996	0.004
Q22.5 Ebstein's anomaly	0.004	0.996	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
C71 Malignant neoplasm of brain	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
M19.94 Arthrosis, unspecified (Hand)	0.000	0.996	0.004
C71.9 Brain, unspecified	0.004	0.996	0.000
Q54 Hypospadias	0.004	0.996	0.000
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.000	0.996	0.004
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.004
Q21.9 Congenital malformation of cardiac septum, unspecified	0.004	0.996	0.000
Q21.3 Tetralogy of Fallot	0.004	0.996	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.996	0.004
Q23.3 Congenital mitral insufficiency	0.004	0.996	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.004	0.996	0.000
Q21.8 Other congenital malformations of cardiac septa	0.004	0.996	0.000
Q21.4 Aortopulmonary septal defect	0.004	0.996	0.000
Q21.2 Atrioventricular septal defect	0.004	0.996	0.000
T47.4 Other laxatives	0.000	0.996	0.004
Z85.6 Personal history of leukaemia	0.000	0.996	0.004
Q23.0 Congenital stenosis of aortic valve	0.004	0.996	0.000
N41 Inflammatory diseases of prostate	0.000	0.996	0.004
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
D52.8 Other folate deficiency anaemias	0.003	0.996	0.000
D52.1 Drug-induced folate deficiency anaemia	0.003	0.996	0.000
D52.0 Dietary folate deficiency anaemia	0.003	0.996	0.000
I45.5 Other specified heart block	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.003	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.003	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.003	0.996	0.000
Q25.3 Stenosis of aorta	0.003	0.996	0.000
Q25.2 Atresia of aorta	0.003	0.996	0.000
T41.5 Therapeutic gases	0.000	0.996	0.003
T41.4 Anaesthetic, unspecified	0.000	0.996	0.003
T41.3 Local anaesthetics	0.000	0.996	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.996	0.003
T41.1 Intravenous anaesthetics	0.000	0.996	0.003
T41.0 Inhaled anaesthetics	0.000	0.996	0.003
T49.9 Topical agent, unspecified	0.000	0.996	0.003
T49.8 Other topical agents	0.000	0.996	0.003
T49.7 Dental drugs, topically applied	0.000	0.996	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.996	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.996	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.996	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.996	0.003
T49.2 Local astringents and local detergents	0.000	0.996	0.003
T49.1 Antipruritics	0.000	0.996	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.003
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
Q25.0 Patent ductus arteriosus	0.003	0.996	0.000
Q54.1 Hypospadias, penile	0.003	0.996	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.003	0.996	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.996	0.003
T37.5 Antiviral drugs	0.000	0.996	0.003
T37.4 Anthelminthics	0.000	0.996	0.003
T37.3 Other antiprotozoal drugs	0.000	0.996	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.996	0.003
T37.1 Antimycobacterial drugs	0.000	0.996	0.003
T37.0 Sulphonamides	0.000	0.996	0.003
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.003	0.996	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.003	0.996	0.000
Q23.4 Hypoplastic left heart syndrome	0.003	0.996	0.000
Q23.2 Congenital mitral stenosis	0.003	0.996	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.003	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
Q54.0 Hypospadias, balanic	0.003	0.997	0.000
S82.30 Fracture of lower end of tibia (closed)	0.003	0.997	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.003	0.997	0.001
Q28.9 Congenital malformation of circulatory system, unspecified	0.003	0.997	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.003	0.997	0.000
Q28.3 Other malformations of cerebral vessels	0.003	0.997	0.000
Q28.1 Other malformations of precerebral vessels	0.003	0.997	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.997	0.003
Q55 Other congenital malformations of male genital organs	0.003	0.997	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.003	0.997	0.000
D51.2 Transcobalamin II deficiency	0.003	0.997	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
G91.8 Other hydrocephalus	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
H61 Other disorders of external ear	0.000	0.997	0.003
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.003	0.997	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q20.6 Isomerism of atrial appendages	0.003	0.997	0.000
Q20.5 Discordant atrioventricular connexion	0.003	0.997	0.000
Q20.4 Double inlet ventricle	0.003	0.997	0.000
Q20.3 Discordant ventriculoarterial connexion	0.003	0.997	0.000
Q20.2 Double outlet left ventricle	0.003	0.997	0.000
Q20.1 Double outlet right ventricle	0.003	0.997	0.000
Q20.0 Common arterial trunk	0.003	0.997	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.003	0.997	0.000
Q26.8 Other congenital malformations of great veins	0.003	0.997	0.000
Q26.6 Portal vein-hepatic artery fistula	0.003	0.997	0.000
Q26.5 Anomalous portal venous connexion	0.003	0.997	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.003	0.997	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.003	0.997	0.000
Q26.1 Persistent left superior vena cava	0.003	0.997	0.000
Q26.0 Congenital stenosis of vena cava	0.003	0.997	0.000
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.003
T36.8 Other systemic antibiotics	0.000	0.997	0.003
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.003
T36.6 Rifamycins	0.000	0.997	0.003
T36.5 Aminoglycosides	0.000	0.997	0.003
T36.4 Tetracyclines	0.000	0.997	0.003
T36.3 Macrolides	0.000	0.997	0.003
T36.2 Chloramphenicol group	0.000	0.997	0.003
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.003
Q35-Q37 Cleft lip and cleft palate	0.003	0.997	0.000
C71.7 Brain stem	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
C71.5 Cerebral ventricle	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.000	0.997	0.003
D50-D53 Nutritional anaemias	0.003	0.997	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.997	0.003
Q54.8 Other hypospadias	0.003	0.997	0.000
Q54.4 Congenital chordee	0.003	0.997	0.000
Q54.3 Hypospadias, perineal	0.003	0.997	0.000
Q54.2 Hypospadias, penoscrotal	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
R57.2 Septic shock	0.000	0.997	0.003
C44.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
Q55.6 Other congenital malformations of penis	0.003	0.997	0.000
I45.6 Preexcitation syndrome	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
G91.0 Communicating hydrocephalus	0.003	0.997	0.001
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
W29.9 Unspecified place	0.003	0.997	0.000
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
Q53 Undescended testicle	0.003	0.997	0.000
C53.9 Cervix uteri, unspecified	0.003	0.997	0.000
Q52 Other congenital malformations of female genitalia	0.003	0.997	0.000
S22.30 Fracture of rib (closed)	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
G91.2 Normal-pressure hydrocephalus	0.002	0.997	0.001
N41.8 Other inflammatory diseases of prostate	0.000	0.997	0.003
N41.3 Prostatocystitis	0.000	0.997	0.003
N41.2 Abscess of prostate	0.000	0.997	0.003
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.003	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.003	0.997	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.997	0.003
Q37 Cleft palate with cleft lip	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.997	0.003
Q30-Q34 Congenital malformations of the respiratory system	0.003	0.997	0.000
D53 Other nutritional anaemias	0.003	0.997	0.000
Q60-Q64 Congenital malformations of the urinary system	0.003	0.997	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.997	0.000
I12 Hypertensive renal disease	0.000	0.997	0.003
H61.9 Disorder of external ear, unspecified	0.000	0.997	0.003
Q53.9 Undescended testicle, unspecified	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.003
T40.8 Lysergide [LSD]	0.000	0.997	0.003
T40.7 Cannabis (derivatives)	0.000	0.997	0.003
T40.5 Cocaine	0.000	0.997	0.003
T40.3 Methadone	0.000	0.997	0.003
T40.1 Heroin	0.000	0.997	0.003
T40.0 Opium	0.000	0.997	0.003
Q35 Cleft palate	0.003	0.997	0.000
J84 Other interstitial pulmonary diseases	0.003	0.997	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.003	0.997	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.997	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.002
Q00-Q07 Congenital malformations of the nervous system	0.003	0.997	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.002	0.997	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.002	0.997	0.000
Q55.5 Congenital absence and aplasia of penis	0.002	0.997	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.002	0.997	0.000
Q55.3 Atresia of vas deferens	0.002	0.997	0.000
Q55.1 Hypoplasia of testis and scrotum	0.002	0.997	0.000
Q55.0 Absence and aplasia of testis	0.002	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.002
H60 Otitis externa	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.000	0.997	0.003
X62.0 Home	0.000	0.997	0.002
X62.8 Other specified place	0.000	0.997	0.002
X62.7 Farm	0.000	0.997	0.002
X62.6 Industrial and construction area	0.000	0.997	0.002
X62.5 Trade and service area	0.000	0.997	0.002
X62.4 Street and highway	0.000	0.997	0.002
X62.3 Sports and athletics area	0.000	0.997	0.002
X62.2 School, other institution and public administrative area	0.000	0.997	0.002
X62.1 Residential institution	0.000	0.997	0.002
Q64 Other congenital malformations of urinary system	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.002
T45.4 Iron and its compounds	0.000	0.997	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.002
X78.0 Home	0.000	0.997	0.003
G12.2 Motor neuron disease	0.003	0.997	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.002	0.997	0.000
T45.5 Anticoagulants	0.000	0.997	0.002
C71.4 Occipital lobe	0.002	0.997	0.000
Q66.2 Metatarsus varus	0.003	0.997	0.000
Q90 Down's syndrome	0.002	0.997	0.000
T48.5 Anti-common-cold drugs	0.001	0.997	0.002
Q36 Cleft lip	0.002	0.997	0.000
H60.3 Other infective otitis externa	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.002	0.997	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.002	0.997	0.000
Q74.1 Congenital malformation of knee	0.002	0.997	0.000
D53.9 Nutritional anaemia, unspecified	0.002	0.997	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.997	0.000
G91.1 Obstructive hydrocephalus	0.002	0.997	0.001
X78 Intentional self-harm by sharp object	0.000	0.997	0.002
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
N41.0 Acute prostatitis	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations