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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs3997849
log Bayes Factor = 84.0835
Chromosome 6   position 32,682,402  (GRCh37) Explore rs3997849 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
H36.0 Diabetic retinopathy
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E10.4 With neurological complications
0.000 0.001 0.999
E10.2 With renal complications
0.000 0.003 0.997
E10.5 With peripheral circulatory complications
0.000 0.006 0.994
E14 Unspecified diabetes mellitus
0.000 0.015 0.985
E50-E64 Other nutritional deficiencies
0.000 0.021 0.979
E00-E07 Disorders of thyroid gland
0.000 0.024 0.976
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.027 0.973
E14.3 With ophthalmic complications
0.000 0.027 0.973
E05.9 Thyrotoxicosis, unspecified
0.000 0.038 0.962
E55 Vitamin D deficiency
0.000 0.050 0.950
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.059 0.941
E55.9 Vitamin D deficiency, unspecified
0.000 0.071 0.929
E11 Non-insulin-dependent diabetes mellitus
0.000 0.072 0.928
J45.9 Asthma, unspecified
0.903 0.097 0.000
E11.3 With ophthalmic complications
0.000 0.099 0.901
E53 Deficiency of other B group vitamins
0.000 0.121 0.879
E10.0 With coma
0.000 0.133 0.867
E10.8 With unspecified complications
0.000 0.137 0.863
E40-E46 Malnutrition
0.000 0.165 0.835
E10.6 With other specified complications
0.000 0.169 0.831
E06 Thyroiditis
0.000 0.193 0.807
E14.5 With peripheral circulatory complications
0.000 0.194 0.806
E14.6 With other specified complications
0.000 0.206 0.794
E11.1 With ketoacidosis
0.000 0.211 0.789
E53.8 Deficiency of other specified B group vitamins
0.000 0.217 0.783
E51 Thiamine deficiency
0.000 0.224 0.776
E14.8 With unspecified complications
0.000 0.231 0.769
E14.2 Withrenal complications
0.000 0.249 0.751
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.278 0.722
E06.3 Autoimmune thyroiditis
0.000 0.280 0.720
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.281 0.719
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E46 Unspecified protein-energy malnutrition
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E11.0 With coma
0.000 0.286 0.714
E14.4 With neurological complications
0.000 0.289 0.711
E14.7 With multiple complications
0.000 0.293 0.706
E14.0 With coma
0.000 0.293 0.706
E70-E90 Metabolic disorders
0.000 0.296 0.704
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.298 0.702
E63 Other nutritional deficiencies
0.000 0.298 0.702
E50 Vitamin A deficiency
0.000 0.298 0.702
E60 Dietary zinc deficiency
0.000 0.298 0.702
E59 Dietary selenium deficiency
0.000 0.298 0.702
E52 Niacin deficiency [pellagra]
0.000 0.298 0.702
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.300 0.700
E00 Congenital iodine-deficiency syndrome
0.000 0.300 0.700
E05.5 Thyroid crisis or storm
0.000 0.302 0.698
E05.4 Thyrotoxicosis factitia
0.000 0.302 0.698
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.302 0.698
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.302 0.698
E53.9 Vitamin B deficiency, unspecified
0.000 0.304 0.696
E11.6 With other specified complications
0.000 0.313 0.687
E54 Ascorbic acid deficiency
0.000 0.315 0.685
E11.5 With peripheral circulatory complications
0.000 0.316 0.684
E55.0 Rickets, active
0.000 0.319 0.681
E11.2 With renal complications
0.000 0.321 0.679
E58 Dietary calcium deficiency
0.000 0.324 0.676
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.329 0.671
E11.7 With multiple complications
0.000 0.334 0.665
E11.8 With unspecified complications
0.000 0.338 0.662
E56 Other vitamin deficiencies
0.000 0.340 0.660
E27.1 Primary adrenocortical insufficiency
0.000 0.342 0.658
E20-E35 Disorders of other endocrine glands
0.000 0.345 0.655
E07 Other disorders of thyroid
0.000 0.348 0.652
E27 Other disorders of adrenal gland
0.000 0.350 0.650
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.356 0.644
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.357 0.643
E51.2 Wernicke's encephalopathy
0.000 0.369 0.631
E53.1 Pyridoxine deficiency
0.000 0.369 0.631
E53.0 Riboflavin deficiency
0.000 0.369 0.631
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.370 0.630
N48.6 Balanitis xerotica obliterans
0.628 0.372 0.000
E87.7 Fluid overload
0.000 0.373 0.627
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.376 0.624
N48 Other disorders of penis
0.620 0.380 0.000
E89.0 Postprocedural hypothyroidism
0.000 0.385 0.615
E16.1 Other hypoglycaemia
0.000 0.388 0.612
E14.1 With ketoacidosis
0.000 0.393 0.607
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.401 0.599
E45 Retarded development following protein-energy malnutrition
0.000 0.401 0.599
E43 Unspecified severe protein-energy malnutrition
0.000 0.401 0.599
E42 Marasmic kwashiorkor
0.000 0.401 0.599
E41 Nutritional marasmus
0.000 0.401 0.599
E40 Kwashiorkor
0.000 0.401 0.599
E05.8 Other thyrotoxicosis
0.000 0.403 0.597
N47 Redundant prepuce, phimosis and paraphimosis
0.597 0.403 0.000
E73 Lactose intolerance
0.000 0.406 0.594
E87.5 Hyperkalaemia
0.000 0.408 0.592
E65-E68 Obesity and other hyperalimentation
0.000 0.415 0.585
E61 Deficiency of other nutrient elements
0.000 0.417 0.583
N48.0 Leukoplakia of penis
0.580 0.420 0.000
E06.4 Drug-induced thyroiditis
0.000 0.421 0.579
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.421 0.579
E06.0 Acute thyroiditis
0.000 0.421 0.579
E06.9 Thyroiditis, unspecified
0.000 0.425 0.575
E83 Disorders of mineral metabolism
0.000 0.439 0.561
E51.9 Thiamine deficiency, unspecified
0.000 0.443 0.557
E51.8 Other manifestations of thiamine deficiency
0.000 0.443 0.557
E51.1 Beriberi
0.000 0.443 0.557
N48.1 Balanoposthitis
0.556 0.444 0.000
G37 Other demyelinating diseases of central nervous system
0.000 0.446 0.554
E83.1 Disorders of iron metabolism
0.000 0.448 0.552
N40-N51 Diseases of male genital organs
0.551 0.449 0.000
E06.5 Other chronic thyroiditis
0.000 0.450 0.550
E89.4 Postprocedural ovarian failure
0.000 0.457 0.543
E79 Disorders of purine and pyrimidine metabolism
0.000 0.459 0.541
E06.1 Subacute thyroiditis
0.000 0.469 0.531
E73.9 Lactose intolerance, unspecified
0.000 0.485 0.515
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E07.8 Other specified disorders of thyroid
0.000 0.486 0.514
E84 Cystic fibrosis
0.000 0.487 0.513
E11.4 With neurological complications
0.000 0.489 0.511
E27.8 Other specified disorders of adrenal gland
0.000 0.490 0.510
E20 Hypoparathyroidism
0.000 0.494 0.506
E28 Ovarian dysfunction
0.000 0.494 0.506
E77 Disorders of glycoprotein metabolism
0.000 0.495 0.505
E76 Disorders of glycosaminoglycan metabolism
0.000 0.495 0.505
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.495 0.505
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.495 0.505
E50.9 Vitamin A deficiency, unspecified
0.000 0.496 0.503
E50.8 Other manifestations of vitamin A deficiency
0.000 0.496 0.503
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.496 0.503
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.496 0.503
E50.5 Vitamin A deficiency with night blindness
0.000 0.496 0.503
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.496 0.503
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.496 0.503
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.496 0.503
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.496 0.503
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.496 0.503
E63.9 Nutritional deficiency, unspecified
0.000 0.496 0.503
E63.8 Other specified nutritional deficiencies
0.000 0.496 0.503
E63.1 Imbalance of constituents of food intake
0.000 0.496 0.503
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.496 0.503
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.496 0.503
E64.8 Sequelae of other nutritional deficiencies
0.000 0.496 0.503
E64.3 Sequelae of rickets
0.000 0.496 0.503
E64.2 Sequelae of vitamin C deficiency
0.000 0.496 0.503
E64.1 Sequelae of vitamin A deficiency
0.000 0.496 0.503
E64.0 Sequelae of protein-energy malnutrition
0.000 0.496 0.503
N48.5 Ulcer of penis
0.503 0.497 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.497 0.503
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.498 0.502
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.498 0.502
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.498 0.502
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.498 0.502
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.498 0.502
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.498 0.502
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.498 0.502
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.498 0.502
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.500 0.500
E87.2 Acidosis
0.000 0.501 0.499
E13 Other specified diabetes mellitus
0.000 0.505 0.494
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.506 0.494
E89.2 Postprocedural hypoparathyroidism
0.000 0.508 0.492
N48.2 Other inflammatory disorders of penis
0.488 0.512 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.516 0.484
E87.4 Mixed disorder of acid-base balance
0.000 0.519 0.481
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.524 0.476
E56.9 Vitamin deficiency, unspecified
0.000 0.527 0.473
E56.8 Deficiency of other vitamins
0.000 0.527 0.473
E56.0 Deficiency of vitamin E
0.000 0.527 0.473
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.530 0.469
E32 Diseases of thymus
0.000 0.530 0.469
E31 Polyglandular dysfunction
0.000 0.530 0.469
E30 Disorders of puberty, not elsewhere classified
0.000 0.530 0.469
E07.1 Dyshormogenetic goitre
0.000 0.532 0.467
E07.0 Hypersecretion of calcitonin
0.000 0.532 0.467
E27.5 Adrenomedullary hyperfunction
0.000 0.534 0.466
E27.0 Other adrenocortical overactivity
0.000 0.534 0.466
M35.0 Sicca syndrome [Sjogren]
0.000 0.538 0.462
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.538 0.462
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.538 0.462
E89.1 Postprocedural hypoinsulinaemia
0.000 0.538 0.462
E22 Hyperfunction of pituitary gland
0.000 0.539 0.461
N48.9 Disorder of penis, unspecified
0.456 0.544 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.544 0.456
G36 Other acute disseminated demyelination
0.000 0.548 0.451
E27.2 Addisonian crisis
0.000 0.560 0.440
N48.3 Priapism
0.439 0.561 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.561 0.439
E28.3 Primary ovarian failure
0.000 0.563 0.437
N41 Inflammatory diseases of prostate
0.436 0.564 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.567 0.433
E56.1 Deficiency of vitamin K
0.000 0.569 0.431
E44.1 Mild protein-energy malnutrition
0.000 0.570 0.429
E44.0 Moderate protein-energy malnutrition
0.000 0.570 0.429
E65 Localised adiposity
0.000 0.572 0.428
E73.8 Other lactose intolerance
0.000 0.574 0.426
E73.1 Secondary lactase deficiency
0.000 0.574 0.426
E73.0 Congenital lactase deficiency
0.000 0.574 0.426
E61.2 Magnesium deficiency
0.000 0.575 0.425
E78.6 Lipoprotein deficiency
0.000 0.575 0.425
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.575 0.425
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.576 0.424
N44 Torsion of testis
0.424 0.576 0.000
E25 Adrenogenital disorders
0.000 0.579 0.420
E67 Other hyperalimentation
0.000 0.581 0.419
E68 Sequelae of hyperalimentation
0.000 0.581 0.419
E61.9 Deficiency of nutrient element, unspecified
0.000 0.582 0.418
E61.8 Deficiency of other specified nutrient elements
0.000 0.582 0.418
E61.7 Deficiency of multiple nutrient elements
0.000 0.582 0.418
E61.6 Vanadium deficiency
0.000 0.582 0.418
E61.5 Molybdenum deficiency
0.000 0.582 0.418
E61.4 Chromium deficiency
0.000 0.582 0.418
E61.3 Manganese deficiency
0.000 0.582 0.418
E61.0 Copper deficiency
0.000 0.582 0.418
N48.8 Other specified disorders of penis
0.414 0.586 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.000 0.588 0.412
M35 Other systemic involvement of connective tissue
0.000 0.591 0.409
E89.5 Postprocedural testicular hypofunction
0.000 0.591 0.409
N51 Disorders of male genital organs in diseases classified elsewhere
0.409 0.591 0.000
E83.8 Other disorders of mineral metabolism
0.000 0.597 0.402
E83.2 Disorders of zinc metabolism
0.000 0.597 0.402
E83.0 Disorders of copper metabolism
0.000 0.597 0.402
M35.3 Polymyalgia rheumatica
0.000 0.598 0.402
E20.9 Hypoparathyroidism, unspecified
0.000 0.600 0.400
G37.5 Concentric sclerosis [Balo]
0.000 0.603 0.397
G37.4 Subacute necrotising myelitis
0.000 0.603 0.397
G37.2 Central pontine myelinolysis
0.000 0.603 0.397
G37.1 Central demyelination of corpus callosum
0.000 0.603 0.397
G37.0 Diffuse sclerosis
0.000 0.603 0.397
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.606 0.394
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.607 0.392
E89.3 Postprocedural hypopituitarism
0.000 0.611 0.389
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.612 0.388
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.612 0.388
E79.1 Lesch-Nyhan syndrome
0.000 0.612 0.388
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.616 0.384
E78.1 Pure hyperglyceridaemia
0.000 0.616 0.384
E74 Other disorders of carbohydrate metabolism
0.000 0.618 0.382
N41.0 Acute prostatitis
0.382 0.618 0.000
E34 Other endocrine disorders
0.000 0.621 0.379
E14.9 Without complications
0.000 0.621 0.379
E29 Testicular dysfunction
0.000 0.622 0.378
E84.9 Cystic fibrosis, unspecified
0.000 0.623 0.377
N41.1 Chronic prostatitis
0.376 0.624 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.629 0.371
E84.8 Cystic fibrosis with other manifestations
0.000 0.632 0.368
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.632 0.368
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.632 0.368
E83.4 Disorders of magnesium metabolism
0.000 0.636 0.364
E20.8 Other hypoparathyroidism
0.000 0.637 0.363
E20.1 Pseudohypoparathyroidism
0.000 0.637 0.363
E20.0 Idiopathic hypoparathyroidism
0.000 0.637 0.363
E28.9 Ovarian dysfunction, unspecified
0.000 0.637 0.363
E28.8 Other ovarian dysfunction
0.000 0.637 0.363
E28.1 Androgen excess
0.000 0.637 0.363
E28.0 Oestrogen excess
0.000 0.637 0.363
E71.3 Disorders of fatty-acid metabolism
0.000 0.638 0.362
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.638 0.362
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.638 0.362
E71.0 Maple-syrup-urine disease
0.000 0.638 0.362
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.638 0.362
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.638 0.362
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.638 0.362
E76.2 Other mucopolysaccharidoses
0.000 0.638 0.362
E76.1 Mucopolysaccharidosis, type II
0.000 0.638 0.362
E76.0 Mucopolysaccharidosis, type I
0.000 0.638 0.362
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.638 0.362
E77.8 Other disorders of glycoprotein metabolism
0.000 0.638 0.362
E77.1 Defects in glycoprotein degradation
0.000 0.638 0.362
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.638 0.362
E22.1 Hyperprolactinaemia
0.000 0.641 0.359
E78.8 Other disorders of lipoprotein metabolism
0.000 0.645 0.355
E13.8 With unspecified complications
0.000 0.645 0.355
E13.7 With multiple complications
0.000 0.645 0.355
E13.6 With other specified complications
0.000 0.645 0.355
E13.5 With peripheral circulatory complications
0.000 0.645 0.355
E13.4 With neurological complications
0.000 0.645 0.355
E13.2 With renal complications
0.000 0.645 0.355
E13.1 With ketoacidosis
0.000 0.645 0.355
E13.0 With coma
0.000 0.645 0.355
E78.3 Hyperchylomicronaemia
0.000 0.646 0.354
E23 Hypofunction and other disorders of pituitary gland
0.000 0.647 0.353
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.653 0.347
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.653 0.347
E70.2 Disorders of tyrosine metabolism
0.000 0.653 0.347
E70.1 Other hyperphenylalaninaemias
0.000 0.653 0.347
E70.0 Classical phenylketonuria
0.000 0.653 0.347
N42 Other disorders of prostate
0.345 0.655 0.000
E13.3 With ophthalmic complications
0.000 0.656 0.344
E22.0 Acromegaly and pituitary gigantism
0.000 0.658 0.342
E07.9 Disorder of thyroid, unspecified
0.000 0.658 0.342
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.339 0.661 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.662 0.338
E30.9 Disorder of puberty, unspecified
0.000 0.663 0.337
E30.8 Other disorders of puberty
0.000 0.663 0.337
E30.1 Precocious puberty
0.000 0.663 0.337
E30.0 Delayed puberty
0.000 0.663 0.337
E31.9 Polyglandular dysfunction, unspecified
0.000 0.663 0.337
E31.8 Other polyglandular dysfunction
0.000 0.663 0.337
E31.1 Polyglandular hyperfunction
0.000 0.663 0.337
E31.0 Autoimmune polyglandular failure
0.000 0.663 0.337
E32.9 Disease of thymus, unspecified
0.000 0.663 0.337
E32.8 Other diseases of thymus
0.000 0.663 0.337
E32.1 Abscess of thymus
0.000 0.663 0.337
E32.0 Persistent hyperplasia of thymus
0.000 0.663 0.337
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.663 0.337
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.663 0.337
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.663 0.337
E26 Hyperaldosteronism
0.001 0.663 0.336
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.664 0.335
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.670 0.330
E22.8 Other hyperfunction of pituitary gland
0.000 0.670 0.330
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.673 0.327
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.673 0.327
E72.5 Disorders of glycine metabolism
0.000 0.673 0.327
E72.4 Disorders of ornithine metabolism
0.000 0.673 0.327
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.673 0.327
E72.2 Disorders of urea cycle metabolism
0.000 0.673 0.327
E70.3 Albinism
0.000 0.673 0.327
G36.9 Acute disseminated demyelination, unspecified
0.000 0.676 0.324
G36.8 Other specified acute disseminated demyelination
0.000 0.676 0.324
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.676 0.324
G36.0 Neuromyelitis optica [Devic]
0.000 0.676 0.324
E88 Other metabolic disorders
0.000 0.678 0.322
N46 Male infertility
0.321 0.679 0.000
M35.7 Hypermobility syndrome
0.000 0.679 0.321
E78.4 Other hyperlipidaemia
0.000 0.682 0.318
J45 Asthma
0.316 0.684 0.000
E87.3 Alkalosis
0.000 0.684 0.316
E75.6 Lipid storage disorder, unspecified
0.000 0.685 0.315
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.685 0.315
E75.3 Sphingolipidosis, unspecified
0.000 0.685 0.315
E75.2 Other sphingolipidosis
0.000 0.685 0.315
E75.1 Other gangliosidosis
0.000 0.685 0.315
E75.0 GM2 gangliosidosis
0.000 0.685 0.315
N41.3 Prostatocystitis
0.312 0.688 0.000
N41.2 Abscess of prostate
0.312 0.688 0.000
K90 Intestinal malabsorption
0.000 0.689 0.311
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.690 0.310
N51.2 Balanitis in diseases classified elsewhere
0.307 0.693 0.000
E72.0 Disorders of amino-acid transport
0.000 0.694 0.306
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.697 0.303
E25.9 Adrenogenital disorder, unspecified
0.000 0.698 0.301
E25.8 Other adrenogenital disorders
0.000 0.698 0.301
E67.8 Other specified hyperalimentation
0.000 0.699 0.301
E67.3 Hypervitaminosis D
0.000 0.699 0.301
E67.2 Megavitamin-B6 syndrome
0.000 0.699 0.301
E67.1 Hypercarotenaemia
0.000 0.699 0.301
E67.0 Hypervitaminosis A
0.000 0.699 0.301
E78.2 Mixed hyperlipidaemia
0.000 0.703 0.297
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.706 0.294
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.706 0.294
M35.5 Multifocal fibrosclerosis
0.000 0.706 0.294
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.706 0.294
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.293 0.707 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.293 0.707 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.293 0.707 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.707 0.293
N42.9 Disorder of prostate, unspecified
0.293 0.707 0.000
E61.1 Iron deficiency
0.000 0.714 0.285
E28.2 Polycystic ovarian syndrome
0.000 0.716 0.284
N45 Orchitis and epididymitis
0.283 0.717 0.000
M35.8 Other specified systemic involvement of connective tissue
0.000 0.717 0.283
E34.9 Endocrine disorder, unspecified
0.000 0.720 0.280
E80.6 Other disorders of bilirubin metabolism
0.000 0.722 0.278
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.724 0.276
E80.5 Crigler-Najjar syndrome
0.000 0.724 0.276
E80.3 Defects of catalase and peroxydase
0.000 0.724 0.276
E80.0 Hereditary erythropoietic porphyria
0.000 0.724 0.276
M35.1 Other overlap syndromes
0.000 0.725 0.274
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.726 0.274
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.726 0.274
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.726 0.274
E74.2 Disorders of galactose metabolism
0.000 0.726 0.274
E74.1 Disorders of fructose metabolism
0.000 0.726 0.274
E80.2 Other porphyria
0.000 0.726 0.274
E34.5 Androgen resistance syndrome
0.000 0.728 0.272
E34.4 Constitutional tall stature
0.000 0.728 0.272
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.728 0.272
E34.1 Other hypersecretion of intestinal hormones
0.000 0.728 0.272
E29.8 Other testicular dysfunction
0.000 0.729 0.271
E29.0 Testicular hyperfunction
0.000 0.729 0.271
N41.8 Other inflammatory diseases of prostate
0.271 0.729 0.000
N48.4 Impotence of organic origin
0.271 0.729 0.000
E66 Obesity
0.000 0.730 0.270
M35.2 Behcet's disease
0.000 0.730 0.269
N42.8 Other specified disorders of prostate
0.266 0.734 0.000
E34.0 Carcinoid syndrome
0.000 0.735 0.265
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.735 0.264
E23.6 Other disorders of pituitary gland
0.000 0.736 0.263
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.742 0.258
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.747 0.253
E23.1 Drug-induced hypopituitarism
0.000 0.747 0.253
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.747 0.252
E88.8 Other specified metabolic disorders
0.000 0.748 0.252
E75.5 Other lipid storage disorders
0.001 0.751 0.249
N42.3 Dysplasia of prostate
0.248 0.752 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.753 0.247
E80.1 Porphyria cutanea tarda
0.000 0.755 0.245
E34.8 Other specified endocrine disorders
0.000 0.755 0.244
E74.0 Glycogen storage disease
0.000 0.756 0.244
N49.9 Inflammatory disorder of unspecified male genital organ
0.243 0.756 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.243 0.756 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.243 0.756 0.000
K90.8 Other intestinal malabsorption
0.000 0.757 0.243
J45.1 Nonallergic asthma
0.243 0.757 0.000
E26.8 Other hyperaldosteronism
0.001 0.758 0.241
E26.1 Secondary hyperaldosteronism
0.001 0.758 0.241
E26.9 Hyperaldosteronism, unspecified
0.001 0.765 0.235
N49.8 Inflammatory disorders of other specified male genital organs
0.234 0.766 0.000
J45.8 Mixed asthma
0.228 0.772 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.776 0.223
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.776 0.223
K90.1 Tropical sprue
0.000 0.776 0.223
E04 Other non-toxic goitre
0.000 0.781 0.219
E34.3 Short stature, not elsewhere classified
0.000 0.781 0.219
E66.0 Obesity due to excess calories
0.000 0.783 0.217
E29.1 Testicular hypofunction
0.000 0.784 0.215
N43 Hydrocele and spermatocele
0.214 0.786 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.788 0.210
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified
0.000 0.789 0.211
N42.1 Congestion and haemorrhage of prostate
0.210 0.790 0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.208 0.792 0.000
E80.4 Gilbert's syndrome
0.000 0.796 0.204
N42.2 Atrophy of prostate
0.204 0.796 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.001 0.798 0.202
N49.2 Inflammatory disorders of scrotum
0.201 0.798 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.803 0.197
E66.8 Other obesity
0.000 0.805 0.195
E66.1 Drug-induced obesity
0.000 0.806 0.194
E04.0 Non-toxic diffuse goitre
0.000 0.808 0.192
E85 Amyloidosis
0.002 0.809 0.189
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.809 0.191
E83.3 Disorders of phosphorus metabolism
0.000 0.810 0.190
E24 Cushing's syndrome
0.003 0.815 0.182
E88.2 Lipomatosis, not elsewhere classified
0.000 0.815 0.184
E03 Other hypothyroidism
0.008 0.818 0.174
E88.3 Tumour lysis syndrome
0.000 0.820 0.180
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.822 0.178
N42.0 Calculus of prostate
0.177 0.823 0.000
J45.0 Predominantly allergic asthma
0.170 0.830 0.000
N43.2 Other hydrocele
0.170 0.830 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.835 0.165
N50 Other disorders of male genital organs
0.163 0.837 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.841 0.159
E13.9 Without complications
0.001 0.841 0.158
E23.2 Diabetes insipidus
0.000 0.841 0.159
N43.1 Infected hydrocele
0.159 0.841 0.000
E04.8 Other specified non-toxic goitre
0.000 0.842 0.157
N43.0 Encysted hydrocele
0.154 0.846 0.000
E86 Volume depletion
0.000 0.847 0.153
E23.0 Hypopituitarism
0.000 0.855 0.145
N41.9 Inflammatory disease of prostate, unspecified
0.141 0.859 0.000
E85.2 Heredofamilial amyloidosis, unspecified
0.002 0.863 0.136
E85.1 Neuropathic heredofamilial amyloidosis
0.002 0.863 0.136
E85.0 Nonneuropathic heredofamilial amyloidosis
0.002 0.863 0.136
E24.8 Other Cushing's syndrome
0.002 0.867 0.131
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.002 0.867 0.131
E24.3 Ectopic ACTH syndrome
0.002 0.867 0.131
E24.1 Nelson's syndrome
0.002 0.867 0.131
E85.8 Other amyloidosis
0.002 0.868 0.130
E03.5 Myxoedema coma
0.006 0.869 0.125
E03.4 Atrophy of thyroid (acquired)
0.006 0.869 0.125
E03.3 Postinfectious hypothyroidism
0.006 0.869 0.125
E03.0 Congenital hypothyroidism with diffuse goitre
0.006 0.869 0.125
K90.9 Intestinal malabsorption, unspecified
0.000 0.872 0.127
N50.0 Atrophy of testis
0.126 0.874 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.877 0.123
E26.0 Primary hyperaldosteronism
0.001 0.877 0.121
E03.1 Congenital hypothyroidism without goitre
0.006 0.880 0.114
N50.9 Disorder of male genital organs, unspecified
0.115 0.885 0.000
E21.2 Other hyperparathyroidism
0.000 0.885 0.114
E21.4 Other specified disorders of parathyroid gland
0.000 0.890 0.110
E24.2 Drug-induced Cushing's syndrome
0.003 0.890 0.107
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.007 0.892 0.101
E85.4 Organ-limited amyloidosis
0.002 0.895 0.103
E85.3 Secondary systemic amyloidosis
0.002 0.897 0.101
N43.4 Spermatocele
0.102 0.897 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.898 0.101
E24.0 Pituitary-dependent Cushing's disease
0.003 0.906 0.090
E03.8 Other specified hypothyroidism
0.007 0.909 0.084

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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