TreeWAS – Variant ID: rs401260

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.002	0.998
E05.9 Thyrotoxicosis, unspecified	0.000	0.004	0.996
E03.8 Other specified hypothyroidism	0.000	0.062	0.938
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.092	0.908
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.161	0.839
E07 Other disorders of thyroid	0.000	0.164	0.836
E03.1 Congenital hypothyroidism without goitre	0.000	0.211	0.789
E07.9 Disorder of thyroid, unspecified	0.000	0.252	0.748
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.716
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.304	0.696
C44.3 Skin of other and unspecified parts of face	0.682	0.318	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.376	0.624
E05.8 Other thyrotoxicosis	0.000	0.398	0.602
E07.1 Dyshormogenetic goitre	0.000	0.401	0.599
E07.0 Hypersecretion of calcitonin	0.000	0.401	0.599
E07.8 Other specified disorders of thyroid	0.000	0.478	0.522
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E06 Thyroiditis	0.000	0.492	0.508
C44 Other malignant neoplasms of skin	0.434	0.566	0.000
C44.5 Skin of trunk	0.429	0.571	0.000
C44.6 Skin of upper limb, including shoulder	0.416	0.584	0.000
E06.5 Other chronic thyroiditis	0.000	0.599	0.401
E06.4 Drug-induced thyroiditis	0.000	0.636	0.364
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.636	0.364
E06.0 Acute thyroiditis	0.000	0.636	0.364
E06.1 Subacute thyroiditis	0.000	0.650	0.349
C44.8 Overlapping lesion of skin	0.312	0.688	0.000
C44.2 Skin of ear and external auricular canal	0.302	0.698	0.000
E06.3 Autoimmune thyroiditis	0.000	0.700	0.300
C44.9 Malignant neoplasm of skin, unspecified	0.280	0.720	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.277	0.723	0.000
E04 Other non-toxic goitre	0.000	0.751	0.249
C43 Malignant melanoma of skin	0.246	0.754	0.000
C43.5 Malignant melanoma of trunk	0.245	0.755	0.000
E06.9 Thyroiditis, unspecified	0.001	0.790	0.209
C43.4 Malignant melanoma of scalp and neck	0.209	0.791	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.201	0.799	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.807	0.193
E04.8 Other specified non-toxic goitre	0.000	0.821	0.179
C43.8 Overlapping malignant melanoma of skin	0.176	0.824	0.000
C43.0 Malignant melanoma of lip	0.176	0.824	0.000
C43.9 Malignant melanoma of skin, unspecified	0.176	0.824	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.172	0.828	0.000
K50.9 Crohn's disease, unspecified	0.000	0.870	0.130
K50 Crohn's disease [regional enteritis]	0.000	0.872	0.128
K50.0 Crohn's disease of small intestine	0.000	0.876	0.124
E04.9 Non-toxic goitre, unspecified	0.000	0.883	0.117
C43.2 Malignant melanoma of ear and external auricular canal	0.114	0.886	0.000
K50.1 Crohn's disease of large intestine	0.000	0.888	0.112
K50.8 Other Crohn's disease	0.000	0.898	0.102
E04.2 Non-toxic multinodular goitre	0.000	0.904	0.096
L43.9 Lichen planus, unspecified	0.000	0.908	0.092
C44.0 Skin of lip	0.092	0.908	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.914	0.086
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.925	0.075
K50-K52 Noninfective enteritis and colitis	0.000	0.933	0.067
E50-E64 Other nutritional deficiencies	0.000	0.935	0.065
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.936	0.064
K51 Ulcerative colitis	0.000	0.937	0.063
E53 Deficiency of other B group vitamins	0.000	0.938	0.062
E53.8 Deficiency of other specified B group vitamins	0.000	0.938	0.062
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.939	0.061
K51.5 Mucosal proctocolitis	0.000	0.941	0.059
C43.6 Malignant melanoma of upper limb, including shoulder	0.057	0.943	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.944	0.056
E58 Dietary calcium deficiency	0.000	0.945	0.055
K51.8 Other ulcerative colitis	0.000	0.947	0.053
E16.2 Hypoglycaemia, unspecified	0.000	0.947	0.053
C44.4 Skin of scalp and neck	0.051	0.949	0.000
E51 Thiamine deficiency	0.000	0.951	0.049
C44.7 Skin of lower limb, including hip	0.049	0.951	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.953	0.047
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.953	0.047
E63 Other nutritional deficiencies	0.000	0.953	0.047
E50 Vitamin A deficiency	0.000	0.953	0.047
E60 Dietary zinc deficiency	0.000	0.953	0.047
E59 Dietary selenium deficiency	0.000	0.953	0.047
E52 Niacin deficiency [pellagra]	0.000	0.953	0.047
E40-E46 Malnutrition	0.000	0.953	0.047
E15 Nondiabetic hypoglycaemic coma	0.000	0.954	0.046
E54 Ascorbic acid deficiency	0.000	0.955	0.045
E53.1 Pyridoxine deficiency	0.000	0.955	0.045
E53.0 Riboflavin deficiency	0.000	0.955	0.045
E56 Other vitamin deficiencies	0.000	0.957	0.043
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.957	0.043
E61 Deficiency of other nutrient elements	0.000	0.959	0.041
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.960	0.040
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.960	0.040
E16.4 Abnormal secretion of gastrin	0.000	0.960	0.040
E16.3 Increased secretion of glucagon	0.000	0.960	0.040
E53.9 Vitamin B deficiency, unspecified	0.000	0.961	0.039
E10-E14 Diabetes mellitus	0.000	0.961	0.039
L43 Lichen planus	0.000	0.962	0.038
E51.2 Wernicke's encephalopathy	0.000	0.963	0.037
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.963	0.037
E14 Unspecified diabetes mellitus	0.000	0.963	0.037
K51.4 Pseudopolyposis of colon	0.000	0.964	0.036
E51.9 Thiamine deficiency, unspecified	0.000	0.965	0.035
E51.8 Other manifestations of thiamine deficiency	0.000	0.965	0.035
E51.1 Beriberi	0.000	0.965	0.035
E16.1 Other hypoglycaemia	0.000	0.965	0.034
E50.9 Vitamin A deficiency, unspecified	0.000	0.966	0.034
E50.8 Other manifestations of vitamin A deficiency	0.000	0.966	0.034
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.966	0.034
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.966	0.034
E50.5 Vitamin A deficiency with night blindness	0.000	0.966	0.034
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.966	0.034
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.966	0.034
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.966	0.034
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.966	0.034
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.966	0.034
E63.9 Nutritional deficiency, unspecified	0.000	0.966	0.034
E63.8 Other specified nutritional deficiencies	0.000	0.966	0.034
E63.1 Imbalance of constituents of food intake	0.000	0.966	0.034
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.966	0.034
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.966	0.034
E64.8 Sequelae of other nutritional deficiencies	0.000	0.966	0.034
E64.3 Sequelae of rickets	0.000	0.966	0.034
E64.2 Sequelae of vitamin C deficiency	0.000	0.966	0.034
E64.1 Sequelae of vitamin A deficiency	0.000	0.966	0.034
E64.0 Sequelae of protein-energy malnutrition	0.000	0.966	0.034
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.966	0.034
E45 Retarded development following protein-energy malnutrition	0.000	0.966	0.034
E43 Unspecified severe protein-energy malnutrition	0.000	0.966	0.034
E42 Marasmic kwashiorkor	0.000	0.966	0.034
E41 Nutritional marasmus	0.000	0.966	0.034
E40 Kwashiorkor	0.000	0.966	0.034
E14.9 Without complications	0.000	0.967	0.033
E56.9 Vitamin deficiency, unspecified	0.000	0.969	0.031
E56.8 Deficiency of other vitamins	0.000	0.969	0.031
E56.0 Deficiency of vitamin E	0.000	0.969	0.031
E14.4 With neurological complications	0.000	0.970	0.030
E61.9 Deficiency of nutrient element, unspecified	0.000	0.970	0.030
E61.8 Deficiency of other specified nutrient elements	0.000	0.970	0.030
E61.7 Deficiency of multiple nutrient elements	0.000	0.970	0.030
E61.6 Vanadium deficiency	0.000	0.970	0.030
E61.5 Molybdenum deficiency	0.000	0.970	0.030
E61.4 Chromium deficiency	0.000	0.970	0.030
E61.3 Manganese deficiency	0.000	0.970	0.030
E61.0 Copper deficiency	0.000	0.970	0.030
E55 Vitamin D deficiency	0.000	0.971	0.029
E14.3 With ophthalmic complications	0.000	0.971	0.029
E61.2 Magnesium deficiency	0.000	0.971	0.029
E14.1 With ketoacidosis	0.000	0.971	0.029
C44.1 Skin of eyelid, including canthus	0.029	0.971	0.000
L43.8 Other lichen planus	0.000	0.972	0.028
E12 Malnutrition-related diabetes mellitus	0.000	0.972	0.028
E14.5 With peripheral circulatory complications	0.000	0.972	0.028
L43.3 Subacute (active) lichen planus	0.000	0.972	0.028
L43.2 Lichenoid drug reaction	0.000	0.972	0.028
L43.1 Bullous lichen planus	0.000	0.972	0.028
E13 Other specified diabetes mellitus	0.000	0.972	0.028
E14.2 Withrenal complications	0.000	0.973	0.027
E46 Unspecified protein-energy malnutrition	0.000	0.973	0.027
E56.1 Deficiency of vitamin K	0.000	0.973	0.027
E14.7 With multiple complications	0.000	0.973	0.027
E14.0 With coma	0.000	0.973	0.027
E14.6 With other specified complications	0.000	0.974	0.026
L43.0 Hypertrophic lichen planus	0.000	0.974	0.026
E65-E68 Obesity and other hyperalimentation	0.000	0.975	0.025
E44.1 Mild protein-energy malnutrition	0.000	0.975	0.024
E44.0 Moderate protein-energy malnutrition	0.000	0.975	0.024
E14.8 With unspecified complications	0.000	0.976	0.024
E61.1 Iron deficiency	0.000	0.976	0.024
K51.2 Ulcerative (chronic) proctitis	0.000	0.977	0.023
E20-E35 Disorders of other endocrine glands	0.000	0.977	0.023
E23.0 Hypopituitarism	0.000	0.978	0.022
E23 Hypofunction and other disorders of pituitary gland	0.000	0.978	0.022
E55.0 Rickets, active	0.000	0.979	0.021
K51.9 Ulcerative colitis, unspecified	0.000	0.979	0.021
E13.3 With ophthalmic complications	0.000	0.979	0.021
E12.9 Without complications	0.000	0.979	0.020
E12.8 With unspecified complications	0.000	0.979	0.020
E12.7 With multiple complications	0.000	0.979	0.020
E12.6 With other specified complications	0.000	0.979	0.020
E12.5 With peripheral circulatory complications	0.000	0.979	0.020
E12.4 With neurological complications	0.000	0.979	0.020
E12.3 With ophthalmic complications	0.000	0.979	0.020
E12.2 With renal complications	0.000	0.979	0.020
E12.1 With ketoacidosis	0.000	0.979	0.020
E12.0 With coma	0.000	0.979	0.020
E13.8 With unspecified complications	0.000	0.980	0.020
E13.7 With multiple complications	0.000	0.980	0.020
E13.6 With other specified complications	0.000	0.980	0.020
E13.5 With peripheral circulatory complications	0.000	0.980	0.020
E13.4 With neurological complications	0.000	0.980	0.020
E13.2 With renal complications	0.000	0.980	0.020
E13.1 With ketoacidosis	0.000	0.980	0.020
E13.0 With coma	0.000	0.980	0.020
E13.9 Without complications	0.000	0.981	0.019
E67 Other hyperalimentation	0.000	0.982	0.018
E68 Sequelae of hyperalimentation	0.000	0.982	0.018
E26 Hyperaldosteronism	0.000	0.983	0.017
E23.7 Disorder of pituitary gland, unspecified	0.000	0.983	0.017
E25 Adrenogenital disorders	0.000	0.983	0.017
E70-E90 Metabolic disorders	0.000	0.983	0.017
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.983	0.017
E32 Diseases of thymus	0.000	0.983	0.017
E31 Polyglandular dysfunction	0.000	0.983	0.017
E30 Disorders of puberty, not elsewhere classified	0.000	0.983	0.017
E24 Cushing's syndrome	0.000	0.983	0.017
K52 Other non-infective gastro-enteritis and colitis	0.000	0.983	0.017
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.984	0.016
E23.1 Drug-induced hypopituitarism	0.000	0.984	0.016
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.984	0.016
E83 Disorders of mineral metabolism	0.000	0.984	0.016
E28 Ovarian dysfunction	0.000	0.984	0.015
K52.1 Toxic gastro-enteritis and colitis	0.000	0.985	0.015
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.985	0.015
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.985	0.015
E83.3 Disorders of phosphorus metabolism	0.000	0.985	0.015
E89.2 Postprocedural hypoparathyroidism	0.000	0.985	0.015
E22 Hyperfunction of pituitary gland	0.000	0.985	0.015
E89.0 Postprocedural hypothyroidism	0.000	0.986	0.014
E83.1 Disorders of iron metabolism	0.000	0.986	0.014
C43.7 Malignant melanoma of lower limb, including hip	0.014	0.986	0.000
E23.2 Diabetes insipidus	0.000	0.986	0.014
E28.3 Primary ovarian failure	0.000	0.986	0.014
E26.9 Hyperaldosteronism, unspecified	0.000	0.986	0.014
E29 Testicular dysfunction	0.000	0.986	0.014
E20 Hypoparathyroidism	0.000	0.987	0.013
E22.0 Acromegaly and pituitary gigantism	0.000	0.987	0.013
E67.8 Other specified hyperalimentation	0.000	0.987	0.013
E67.3 Hypervitaminosis D	0.000	0.987	0.013
E67.2 Megavitamin-B6 syndrome	0.000	0.987	0.013
E67.1 Hypercarotenaemia	0.000	0.987	0.013
E67.0 Hypervitaminosis A	0.000	0.987	0.013
E88 Other metabolic disorders	0.000	0.987	0.013
E24.9 Cushing's syndrome, unspecified	0.000	0.987	0.013
E74 Other disorders of carbohydrate metabolism	0.000	0.987	0.013
E79 Disorders of purine and pyrimidine metabolism	0.000	0.987	0.013
E72 Other disorders of amino-acid metabolism	0.000	0.987	0.013
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.987	0.013
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.987	0.013
E26.8 Other hyperaldosteronism	0.000	0.987	0.012
E26.1 Secondary hyperaldosteronism	0.000	0.987	0.012
E25.9 Adrenogenital disorder, unspecified	0.000	0.987	0.012
E25.8 Other adrenogenital disorders	0.000	0.987	0.012
E77 Disorders of glycoprotein metabolism	0.000	0.988	0.012
E76 Disorders of glycosaminoglycan metabolism	0.000	0.988	0.012
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.988	0.012
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.988	0.012
E30.9 Disorder of puberty, unspecified	0.000	0.988	0.012
E30.8 Other disorders of puberty	0.000	0.988	0.012
E30.1 Precocious puberty	0.000	0.988	0.012
E30.0 Delayed puberty	0.000	0.988	0.012
E31.9 Polyglandular dysfunction, unspecified	0.000	0.988	0.012
E31.8 Other polyglandular dysfunction	0.000	0.988	0.012
E31.1 Polyglandular hyperfunction	0.000	0.988	0.012
E32.9 Disease of thymus, unspecified	0.000	0.988	0.012
E32.8 Other diseases of thymus	0.000	0.988	0.012
E32.1 Abscess of thymus	0.000	0.988	0.012
E32.0 Persistent hyperplasia of thymus	0.000	0.988	0.012
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.988	0.012
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.988	0.012
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.988	0.012
E31.0 Autoimmune polyglandular failure	0.000	0.988	0.012
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.988	0.012
E24.3 Ectopic ACTH syndrome	0.000	0.988	0.012
E24.1 Nelson's syndrome	0.000	0.988	0.012
E24.0 Pituitary-dependent Cushing's disease	0.000	0.988	0.012
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.988	0.012
E70 Disorders of aromatic amino-acid metabolism	0.000	0.988	0.012
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.988	0.012
E21.2 Other hyperparathyroidism	0.000	0.988	0.012
E24.8 Other Cushing's syndrome	0.000	0.988	0.012
E84 Cystic fibrosis	0.000	0.988	0.011
E24.2 Drug-induced Cushing's syndrome	0.000	0.988	0.011
E83.8 Other disorders of mineral metabolism	0.000	0.988	0.011
E83.2 Disorders of zinc metabolism	0.000	0.988	0.011
E83.0 Disorders of copper metabolism	0.000	0.988	0.011
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.988	0.011
E89.1 Postprocedural hypoinsulinaemia	0.000	0.988	0.011
E28.9 Ovarian dysfunction, unspecified	0.000	0.989	0.011
E28.8 Other ovarian dysfunction	0.000	0.989	0.011
E28.1 Androgen excess	0.000	0.989	0.011
E28.0 Oestrogen excess	0.000	0.989	0.011
E83.4 Disorders of magnesium metabolism	0.000	0.989	0.011
E85 Amyloidosis	0.000	0.989	0.011
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.989	0.011
E10 Insulin-dependent diabetes mellitus	0.000	0.989	0.011
E26.0 Primary hyperaldosteronism	0.000	0.989	0.011
E73 Lactose intolerance	0.000	0.989	0.011
E89.5 Postprocedural testicular hypofunction	0.000	0.989	0.011
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.989	0.011
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.989	0.011
E27 Other disorders of adrenal gland	0.000	0.989	0.011
O47.1 False labour at or after 37 completed weeks of gestation	0.011	0.989	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.989	0.011
E22.8 Other hyperfunction of pituitary gland	0.000	0.989	0.011
E23.6 Other disorders of pituitary gland	0.000	0.989	0.011
E88.2 Lipomatosis, not elsewhere classified	0.000	0.989	0.011
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.989	0.010
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.989	0.010
E21.3 Hyperparathyroidism, unspecified	0.000	0.990	0.010
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.990	0.010
E29.9 Testicular dysfunction, unspecified	0.000	0.990	0.010
E29.8 Other testicular dysfunction	0.000	0.990	0.010
E29.0 Testicular hyperfunction	0.000	0.990	0.010
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.990	0.010
E88.8 Other specified metabolic disorders	0.000	0.990	0.010
E21.4 Other specified disorders of parathyroid gland	0.000	0.990	0.010
E88.9 Metabolic disorder, unspecified	0.000	0.990	0.010
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.990	0.010
E20.8 Other hypoparathyroidism	0.000	0.990	0.010
E20.1 Pseudohypoparathyroidism	0.000	0.990	0.010
E20.0 Idiopathic hypoparathyroidism	0.000	0.990	0.010
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.990	0.010
E72.0 Disorders of amino-acid transport	0.000	0.990	0.010
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.990	0.010
E89.3 Postprocedural hypopituitarism	0.000	0.990	0.010
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.990	0.009
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.990	0.009
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.990	0.009
E74.2 Disorders of galactose metabolism	0.000	0.990	0.009
E74.1 Disorders of fructose metabolism	0.000	0.990	0.009
E74.0 Glycogen storage disease	0.000	0.990	0.009
E88.3 Tumour lysis syndrome	0.000	0.991	0.009
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.991	0.009
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.991	0.009
E79.1 Lesch-Nyhan syndrome	0.000	0.991	0.009
K52.3 Indeterminate colitis	0.000	0.991	0.009
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.991	0.009
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.991	0.009
E72.5 Disorders of glycine metabolism	0.000	0.991	0.009
E72.4 Disorders of ornithine metabolism	0.000	0.991	0.009
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.991	0.009
E72.2 Disorders of urea cycle metabolism	0.000	0.991	0.009
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.991	0.009
O47.0 False labour before 37 completed weeks of gestation	0.009	0.991	0.000
E89.4 Postprocedural ovarian failure	0.000	0.991	0.009
E65 Localised adiposity	0.000	0.991	0.009
E71.3 Disorders of fatty-acid metabolism	0.000	0.991	0.009
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.991	0.009
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.991	0.009
E71.0 Maple-syrup-urine disease	0.000	0.991	0.009
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.991	0.009
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.991	0.009
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.991	0.009
E76.2 Other mucopolysaccharidoses	0.000	0.991	0.009
E76.1 Mucopolysaccharidosis, type II	0.000	0.991	0.009
E76.0 Mucopolysaccharidosis, type I	0.000	0.991	0.009
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.991	0.009
E77.8 Other disorders of glycoprotein metabolism	0.000	0.991	0.009
E77.1 Defects in glycoprotein degradation	0.000	0.991	0.009
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.991	0.009
E10.4 With neurological complications	0.000	0.991	0.009
O47 False labour	0.009	0.991	0.000
E66 Obesity	0.000	0.991	0.009
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.991	0.009
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.991	0.009
E70.2 Disorders of tyrosine metabolism	0.000	0.991	0.009
E70.1 Other hyperphenylalaninaemias	0.000	0.991	0.009
E70.0 Classical phenylketonuria	0.000	0.991	0.009
E10.1 With ketoacidosis	0.000	0.991	0.009
E10.0 With coma	0.000	0.991	0.009
E75.6 Lipid storage disorder, unspecified	0.000	0.991	0.009
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.991	0.009
E75.3 Sphingolipidosis, unspecified	0.000	0.991	0.009
E75.1 Other gangliosidosis	0.000	0.991	0.009
E75.0 GM2 gangliosidosis	0.000	0.991	0.009
E85.8 Other amyloidosis	0.000	0.991	0.009
E84.9 Cystic fibrosis, unspecified	0.000	0.991	0.009
E10.7 With multiple complications	0.000	0.991	0.009
E85.4 Organ-limited amyloidosis	0.000	0.991	0.009
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.991	0.009
E84.8 Cystic fibrosis with other manifestations	0.000	0.991	0.008
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.991	0.008
E75.5 Other lipid storage disorders	0.000	0.991	0.008
E10.6 With other specified complications	0.000	0.991	0.008
E70.3 Albinism	0.000	0.992	0.008
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.992	0.008
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.992	0.008
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.992	0.008
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.992	0.008
E75.2 Other sphingolipidosis	0.000	0.992	0.008
E73.8 Other lactose intolerance	0.000	0.992	0.008
E73.1 Secondary lactase deficiency	0.000	0.992	0.008
E73.0 Congenital lactase deficiency	0.000	0.992	0.008
E27.5 Adrenomedullary hyperfunction	0.000	0.992	0.008
E27.0 Other adrenocortical overactivity	0.000	0.992	0.008
S83.2 Tear of meniscus, current	0.000	0.992	0.008
E27.1 Primary adrenocortical insufficiency	0.000	0.992	0.008
E22.1 Hyperprolactinaemia	0.000	0.992	0.008
E83.5 Disorders of calcium metabolism	0.000	0.992	0.008
E85.9 Amyloidosis, unspecified	0.000	0.992	0.008
E10.2 With renal complications	0.000	0.992	0.008
M87.9 Osteonecrosis, unspecified	0.000	0.992	0.008
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.992	0.007
E10.9 Without complications	0.000	0.992	0.008
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.992	0.008
E34 Other endocrine disorders	0.001	0.993	0.007
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.993	0.007
M87.2 Osteonecrosis due to previous trauma	0.000	0.993	0.007
E85.3 Secondary systemic amyloidosis	0.000	0.993	0.007
O66.0 Obstructed labour due to shoulder dystocia	0.007	0.993	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.993	0.007
E73.9 Lactose intolerance, unspecified	0.000	0.993	0.007
E29.1 Testicular hypofunction	0.000	0.993	0.007
E27.2 Addisonian crisis	0.000	0.993	0.007
O47.9 False labour, unspecified	0.007	0.993	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.993	0.007
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.993	0.007
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
H54.0 Blindness, both eyes	0.007	0.993	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.007	0.993	0.000
M87 Osteonecrosis	0.000	0.993	0.007
E78.4 Other hyperlipidaemia	0.000	0.993	0.007
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.993	0.007
E66.1 Drug-induced obesity	0.000	0.993	0.007
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.993	0.007
T79.6 Traumatic ischaemia of muscle	0.000	0.993	0.007
E20.9 Hypoparathyroidism, unspecified	0.001	0.994	0.006
E10.8 With unspecified complications	0.000	0.994	0.006
E27.9 Disorder of adrenal gland, unspecified	0.000	0.994	0.006
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.994	0.006
M87.8 Other osteonecrosis	0.000	0.994	0.006
F31 Bipolar affective disorder	0.006	0.994	0.000
E21.0 Primary hyperparathyroidism	0.000	0.994	0.006
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.006	0.994	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.006	0.994	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.994	0.006
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.994	0.006
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.994	0.006
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.994	0.006
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.994	0.006
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.994	0.006
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.994	0.006
E66.0 Obesity due to excess calories	0.000	0.994	0.006
E34.5 Androgen resistance syndrome	0.001	0.994	0.005
E34.4 Constitutional tall stature	0.001	0.994	0.005
E34.2 Ectopic hormone secretion, not elsewhere classified	0.001	0.994	0.005
E34.1 Other hypersecretion of intestinal hormones	0.001	0.994	0.005
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.994	0.005
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.994	0.005
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.994	0.005
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.994	0.005
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.994	0.005
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.994	0.005
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.994	0.005
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.994	0.005
E78.1 Pure hyperglyceridaemia	0.000	0.994	0.006
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.994	0.005
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.994	0.005
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.995	0.005
C53.9 Cervix uteri, unspecified	0.000	0.995	0.005
N30.1 Interstitial cystitis (chronic)	0.005	0.995	0.000
Z88.5 Personal history of allergy to narcotic agent	0.005	0.995	0.000
W25.9 Unspecified place	0.000	0.995	0.005
E78.3 Hyperchylomicronaemia	0.000	0.995	0.005
S83.3 Tear of articular cartilage of knee, current	0.000	0.995	0.005
E34.3 Short stature, not elsewhere classified	0.001	0.995	0.004
C22.9 Liver, unspecified	0.000	0.995	0.005
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.005	0.995	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.995	0.005
F31.7 Bipolar affective disorder, currently in remission	0.005	0.995	0.000
M87.3 Other secondary osteonecrosis	0.000	0.995	0.005
E27.8 Other specified disorders of adrenal gland	0.000	0.995	0.005
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.995	0.005
O66 Other obstructed labour	0.005	0.995	0.000
M87.1 Osteonecrosis due to drugs	0.000	0.995	0.005
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.005	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.005	0.995	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.995	0.005
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.995	0.005
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.005	0.995	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.995	0.005
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.995	0.005
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.995	0.005
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
E78.6 Lipoprotein deficiency	0.000	0.995	0.005
E34.9 Endocrine disorder, unspecified	0.001	0.995	0.004
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.995	0.005
M87.88 Other osteonecrosis (Other)	0.000	0.995	0.005
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.995	0.005
M87.86 Other osteonecrosis (Lower leg)	0.000	0.995	0.005
M87.84 Other osteonecrosis (Hand)	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations