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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs402749
log Bayes Factor = 15.3577
Chromosome 6   position 167,386,104  (GRCh37) Explore rs402749 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.002 0.998
E05.9 Thyrotoxicosis, unspecified
0.000 0.003 0.997
E03.8 Other specified hypothyroidism
0.000 0.061 0.939
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.089 0.911
E07 Other disorders of thyroid
0.000 0.140 0.860
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.160 0.840
E03.1 Congenital hypothyroidism without goitre
0.000 0.210 0.790
E07.9 Disorder of thyroid, unspecified
0.000 0.215 0.785
E05.5 Thyroid crisis or storm
0.000 0.283 0.717
E05.4 Thyrotoxicosis factitia
0.000 0.283 0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.283 0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.302 0.698
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.375 0.624
E07.1 Dyshormogenetic goitre
0.000 0.383 0.617
E07.0 Hypersecretion of calcitonin
0.000 0.383 0.617
E05.8 Other thyrotoxicosis
0.000 0.396 0.604
C44.3 Skin of other and unspecified parts of face
0.591 0.409 0.000
E07.8 Other specified disorders of thyroid
0.000 0.463 0.537
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E06 Thyroiditis
0.000 0.511 0.489
E06.5 Other chronic thyroiditis
0.000 0.614 0.386
E06.4 Drug-induced thyroiditis
0.000 0.649 0.350
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.649 0.350
E06.0 Acute thyroiditis
0.000 0.649 0.350
E06.1 Subacute thyroiditis
0.000 0.663 0.337
C44 Other malignant neoplasms of skin
0.285 0.715 0.000
C44.5 Skin of trunk
0.282 0.718 0.000
E06.3 Autoimmune thyroiditis
0.000 0.720 0.280
C44.6 Skin of upper limb, including shoulder
0.266 0.734 0.000
E04 Other non-toxic goitre
0.000 0.746 0.254
K50.9 Crohn's disease, unspecified
0.000 0.759 0.241
K50 Crohn's disease [regional enteritis]
0.000 0.763 0.237
K50.0 Crohn's disease of small intestine
0.000 0.769 0.231
C44.8 Overlapping lesion of skin
0.205 0.795 0.000
K50.1 Crohn's disease of large intestine
0.000 0.797 0.203
C44.2 Skin of ear and external auricular canal
0.201 0.799 0.000
E04.0 Non-toxic diffuse goitre
0.000 0.803 0.197
E06.9 Thyroiditis, unspecified
0.001 0.808 0.191
K50.8 Other Crohn's disease
0.000 0.814 0.186
C44.9 Malignant neoplasm of skin, unspecified
0.183 0.817 0.000
E04.8 Other specified non-toxic goitre
0.000 0.818 0.182
C43-C44 Melanoma and other malignant neoplasms of skin
0.170 0.830 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.847 0.153
C43.5 Malignant melanoma of trunk
0.147 0.853 0.000
C43 Malignant melanoma of skin
0.147 0.853 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.858 0.142
K51 Ulcerative colitis
0.000 0.865 0.135
E50-E64 Other nutritional deficiencies
0.000 0.866 0.134
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.870 0.130
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.871 0.129
E53 Deficiency of other B group vitamins
0.000 0.874 0.126
K51.5 Mucosal proctocolitis
0.000 0.874 0.126
E53.8 Deficiency of other specified B group vitamins
0.000 0.877 0.123
C43.3 Malignant melanoma of other and unspecified parts of face
0.122 0.878 0.000
C43.4 Malignant melanoma of scalp and neck
0.122 0.878 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.882 0.118
K51.8 Other ulcerative colitis
0.000 0.885 0.115
E16 Other disorders of pancreatic internal secretion
0.000 0.887 0.113
E58 Dietary calcium deficiency
0.000 0.888 0.112
E10-E14 Diabetes mellitus
0.000 0.888 0.112
E14 Unspecified diabetes mellitus
0.000 0.891 0.109
C43.9 Malignant melanoma of skin, unspecified
0.108 0.892 0.000
E16.2 Hypoglycaemia, unspecified
0.000 0.894 0.106
C43.8 Overlapping malignant melanoma of skin
0.106 0.894 0.000
C43.0 Malignant melanoma of lip
0.106 0.894 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.103 0.897 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.898 0.102
E14.9 Without complications
0.000 0.899 0.101
E51 Thiamine deficiency
0.000 0.899 0.100
E40-E46 Malnutrition
0.000 0.900 0.099
E04.1 Non-toxic single thyroid nodule
0.000 0.904 0.096
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.904 0.096
E63 Other nutritional deficiencies
0.000 0.904 0.096
E50 Vitamin A deficiency
0.000 0.904 0.096
E60 Dietary zinc deficiency
0.000 0.904 0.096
E59 Dietary selenium deficiency
0.000 0.904 0.096
E52 Niacin deficiency [pellagra]
0.000 0.904 0.096
E15 Nondiabetic hypoglycaemic coma
0.000 0.907 0.093
E54 Ascorbic acid deficiency
0.000 0.907 0.093
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.908 0.092
E04.2 Non-toxic multinodular goitre
0.000 0.908 0.092
E53.1 Pyridoxine deficiency
0.000 0.909 0.091
E53.0 Riboflavin deficiency
0.000 0.909 0.091
E14.4 With neurological complications
0.000 0.912 0.088
E56 Other vitamin deficiencies
0.000 0.912 0.087
E14.3 With ophthalmic complications
0.000 0.913 0.087
E61 Deficiency of other nutrient elements
0.000 0.915 0.085
E14.1 With ketoacidosis
0.000 0.916 0.084
E53.9 Vitamin B deficiency, unspecified
0.000 0.917 0.083
E14.5 With peripheral circulatory complications
0.000 0.918 0.082
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.919 0.081
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.919 0.081
E16.4 Abnormal secretion of gastrin
0.000 0.919 0.081
E16.3 Increased secretion of glucagon
0.000 0.919 0.081
E12 Malnutrition-related diabetes mellitus
0.000 0.920 0.080
E13 Other specified diabetes mellitus
0.000 0.921 0.079
K51.4 Pseudopolyposis of colon
0.000 0.921 0.079
E14.2 Withrenal complications
0.000 0.921 0.079
E14.7 With multiple complications
0.000 0.922 0.078
E14.0 With coma
0.000 0.922 0.078
E51.2 Wernicke's encephalopathy
0.000 0.923 0.077
E14.6 With other specified complications
0.000 0.924 0.075
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.925 0.075
E14.8 With unspecified complications
0.000 0.925 0.074
E51.9 Thiamine deficiency, unspecified
0.000 0.928 0.072
E51.8 Other manifestations of thiamine deficiency
0.000 0.928 0.072
E51.1 Beriberi
0.000 0.928 0.072
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.928 0.071
E45 Retarded development following protein-energy malnutrition
0.000 0.928 0.071
E43 Unspecified severe protein-energy malnutrition
0.000 0.928 0.071
E42 Marasmic kwashiorkor
0.000 0.928 0.071
E41 Nutritional marasmus
0.000 0.928 0.071
E40 Kwashiorkor
0.000 0.928 0.071
E16.1 Other hypoglycaemia
0.000 0.930 0.070
E50.9 Vitamin A deficiency, unspecified
0.000 0.931 0.069
E50.8 Other manifestations of vitamin A deficiency
0.000 0.931 0.069
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.931 0.069
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.931 0.069
E50.5 Vitamin A deficiency with night blindness
0.000 0.931 0.069
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.931 0.069
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.931 0.069
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.931 0.069
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.931 0.069
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.931 0.069
E63.9 Nutritional deficiency, unspecified
0.000 0.931 0.069
E63.8 Other specified nutritional deficiencies
0.000 0.931 0.069
E63.1 Imbalance of constituents of food intake
0.000 0.931 0.069
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.931 0.069
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.931 0.069
E64.8 Sequelae of other nutritional deficiencies
0.000 0.931 0.069
E64.3 Sequelae of rickets
0.000 0.931 0.069
E64.2 Sequelae of vitamin C deficiency
0.000 0.931 0.069
E64.1 Sequelae of vitamin A deficiency
0.000 0.931 0.069
E64.0 Sequelae of protein-energy malnutrition
0.000 0.931 0.069
C43.2 Malignant melanoma of ear and external auricular canal
0.068 0.932 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.936 0.064
E56.9 Vitamin deficiency, unspecified
0.000 0.937 0.063
E56.8 Deficiency of other vitamins
0.000 0.937 0.063
E56.0 Deficiency of vitamin E
0.000 0.937 0.063
C44.0 Skin of lip
0.062 0.938 0.000
E23.0 Hypopituitarism
0.000 0.938 0.062
E23 Hypofunction and other disorders of pituitary gland
0.000 0.939 0.061
E61.9 Deficiency of nutrient element, unspecified
0.000 0.939 0.061
E61.8 Deficiency of other specified nutrient elements
0.000 0.939 0.061
E61.7 Deficiency of multiple nutrient elements
0.000 0.939 0.061
E61.6 Vanadium deficiency
0.000 0.939 0.061
E61.5 Molybdenum deficiency
0.000 0.939 0.061
E61.4 Chromium deficiency
0.000 0.939 0.061
E61.3 Manganese deficiency
0.000 0.939 0.061
E61.0 Copper deficiency
0.000 0.939 0.061
E46 Unspecified protein-energy malnutrition
0.000 0.939 0.061
E61.2 Magnesium deficiency
0.000 0.940 0.060
E55 Vitamin D deficiency
0.000 0.940 0.060
E13.3 With ophthalmic complications
0.000 0.941 0.059
E12.9 Without complications
0.000 0.942 0.058
E12.8 With unspecified complications
0.000 0.942 0.058
E12.7 With multiple complications
0.000 0.942 0.058
E12.6 With other specified complications
0.000 0.942 0.058
E12.5 With peripheral circulatory complications
0.000 0.942 0.058
E12.4 With neurological complications
0.000 0.942 0.058
E12.3 With ophthalmic complications
0.000 0.942 0.058
E12.2 With renal complications
0.000 0.942 0.058
E12.1 With ketoacidosis
0.000 0.942 0.058
E12.0 With coma
0.000 0.942 0.058
E13.8 With unspecified complications
0.000 0.943 0.057
E13.7 With multiple complications
0.000 0.943 0.057
E13.6 With other specified complications
0.000 0.943 0.057
E13.5 With peripheral circulatory complications
0.000 0.943 0.057
E13.4 With neurological complications
0.000 0.943 0.057
E13.2 With renal complications
0.000 0.943 0.057
E13.1 With ketoacidosis
0.000 0.943 0.057
E13.0 With coma
0.000 0.943 0.057
E56.1 Deficiency of vitamin K
0.000 0.945 0.054
E13.9 Without complications
0.000 0.946 0.054
K51.2 Ulcerative (chronic) proctitis
0.000 0.948 0.052
E44.1 Mild protein-energy malnutrition
0.000 0.948 0.051
E44.0 Moderate protein-energy malnutrition
0.000 0.948 0.051
E61.1 Iron deficiency
0.000 0.949 0.051
E10 Insulin-dependent diabetes mellitus
0.000 0.950 0.050
E65-E68 Obesity and other hyperalimentation
0.000 0.950 0.050
K51.9 Ulcerative colitis, unspecified
0.000 0.951 0.049
E23.7 Disorder of pituitary gland, unspecified
0.000 0.952 0.048
E26 Hyperaldosteronism
0.000 0.953 0.047
E25 Adrenogenital disorders
0.000 0.953 0.047
E31 Polyglandular dysfunction
0.000 0.954 0.046
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.954 0.046
E32 Diseases of thymus
0.000 0.954 0.046
E30 Disorders of puberty, not elsewhere classified
0.000 0.954 0.046
L43.9 Lichen planus, unspecified
0.000 0.954 0.046
E22 Hyperfunction of pituitary gland
0.000 0.954 0.046
E24 Cushing's syndrome
0.000 0.955 0.045
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.956 0.044
E23.1 Drug-induced hypopituitarism
0.000 0.956 0.044
K52 Other non-infective gastro-enteritis and colitis
0.000 0.956 0.044
E55.0 Rickets, active
0.000 0.957 0.043
E28 Ovarian dysfunction
0.000 0.957 0.043
E22.0 Acromegaly and pituitary gigantism
0.000 0.958 0.042
E10.4 With neurological complications
0.000 0.959 0.041
C44.7 Skin of lower limb, including hip
0.040 0.960 0.000
E23.2 Diabetes insipidus
0.000 0.960 0.040
K52.1 Toxic gastro-enteritis and colitis
0.000 0.960 0.040
E10.9 Without complications
0.000 0.961 0.039
E10.1 With ketoacidosis
0.000 0.961 0.039
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.961 0.039
E10.0 With coma
0.000 0.962 0.038
E26.9 Hyperaldosteronism, unspecified
0.000 0.962 0.038
E28.3 Primary ovarian failure
0.000 0.962 0.038
E10.7 With multiple complications
0.000 0.962 0.038
E10.6 With other specified complications
0.000 0.963 0.037
E29 Testicular dysfunction
0.000 0.963 0.037
E20 Hypoparathyroidism
0.000 0.963 0.036
E70-E90 Metabolic disorders
0.000 0.964 0.036
E67 Other hyperalimentation
0.000 0.964 0.036
E68 Sequelae of hyperalimentation
0.000 0.964 0.036
E24.9 Cushing's syndrome, unspecified
0.000 0.965 0.035
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.965 0.034
E10.2 With renal complications
0.000 0.966 0.034
E26.8 Other hyperaldosteronism
0.000 0.966 0.034
E26.1 Secondary hyperaldosteronism
0.000 0.966 0.034
E25.9 Adrenogenital disorder, unspecified
0.000 0.966 0.034
E25.8 Other adrenogenital disorders
0.000 0.966 0.034
E31.9 Polyglandular dysfunction, unspecified
0.000 0.967 0.033
E31.8 Other polyglandular dysfunction
0.000 0.967 0.033
E31.1 Polyglandular hyperfunction
0.000 0.967 0.033
E31.0 Autoimmune polyglandular failure
0.000 0.967 0.033
E30.9 Disorder of puberty, unspecified
0.000 0.967 0.033
E30.8 Other disorders of puberty
0.000 0.967 0.033
E30.1 Precocious puberty
0.000 0.967 0.033
E30.0 Delayed puberty
0.000 0.967 0.033
E32.9 Disease of thymus, unspecified
0.000 0.967 0.033
E32.8 Other diseases of thymus
0.000 0.967 0.033
E32.1 Abscess of thymus
0.000 0.967 0.033
E32.0 Persistent hyperplasia of thymus
0.000 0.967 0.033
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.967 0.033
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.967 0.033
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.967 0.033
E83 Disorders of mineral metabolism
0.000 0.967 0.033
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.967 0.033
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.967 0.033
E22.8 Other hyperfunction of pituitary gland
0.000 0.967 0.033
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.967 0.033
E24.3 Ectopic ACTH syndrome
0.000 0.967 0.033
E24.1 Nelson's syndrome
0.000 0.967 0.033
E24.0 Pituitary-dependent Cushing's disease
0.000 0.967 0.033
C44.4 Skin of scalp and neck
0.032 0.968 0.000
E24.8 Other Cushing's syndrome
0.000 0.968 0.031
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.969 0.031
E27 Other disorders of adrenal gland
0.000 0.969 0.031
E28.9 Ovarian dysfunction, unspecified
0.000 0.969 0.031
E28.8 Other ovarian dysfunction
0.000 0.969 0.031
E28.1 Androgen excess
0.000 0.969 0.031
E28.0 Oestrogen excess
0.000 0.969 0.031
E26.0 Primary hyperaldosteronism
0.000 0.969 0.031
E89.0 Postprocedural hypothyroidism
0.000 0.969 0.031
C43.6 Malignant melanoma of upper limb, including shoulder
0.030 0.969 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.970 0.030
E89.2 Postprocedural hypoparathyroidism
0.000 0.970 0.030
E23.6 Other disorders of pituitary gland
0.000 0.970 0.030
E21.2 Other hyperparathyroidism
0.000 0.970 0.030
E83.1 Disorders of iron metabolism
0.000 0.970 0.030
E24.2 Drug-induced Cushing's syndrome
0.000 0.970 0.030
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.971 0.029
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.971 0.028
E10.8 With unspecified complications
0.000 0.972 0.027
E88 Other metabolic disorders
0.000 0.972 0.028
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.973 0.027
K52.3 Indeterminate colitis
0.000 0.973 0.027
E79 Disorders of purine and pyrimidine metabolism
0.000 0.973 0.027
E72 Other disorders of amino-acid metabolism
0.000 0.973 0.027
E74 Other disorders of carbohydrate metabolism
0.000 0.973 0.027
E29.9 Testicular dysfunction, unspecified
0.000 0.973 0.027
E29.8 Other testicular dysfunction
0.000 0.973 0.027
E29.0 Testicular hyperfunction
0.000 0.973 0.027
E20.8 Other hypoparathyroidism
0.000 0.973 0.026
E20.1 Pseudohypoparathyroidism
0.000 0.973 0.026
E20.0 Idiopathic hypoparathyroidism
0.000 0.973 0.026
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.974 0.026
E77 Disorders of glycoprotein metabolism
0.000 0.974 0.026
E76 Disorders of glycosaminoglycan metabolism
0.000 0.974 0.026
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.974 0.026
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.974 0.026
E67.8 Other specified hyperalimentation
0.000 0.974 0.026
E67.3 Hypervitaminosis D
0.000 0.974 0.026
E67.2 Megavitamin-B6 syndrome
0.000 0.974 0.026
E67.1 Hypercarotenaemia
0.000 0.974 0.026
E67.0 Hypervitaminosis A
0.000 0.974 0.026
E21.4 Other specified disorders of parathyroid gland
0.000 0.974 0.026
E83.4 Disorders of magnesium metabolism
0.000 0.975 0.025
E70 Disorders of aromatic amino-acid metabolism
0.000 0.975 0.025
E21.3 Hyperparathyroidism, unspecified
0.000 0.975 0.025
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.975 0.025
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.975 0.025
E84 Cystic fibrosis
0.000 0.975 0.025
E85 Amyloidosis
0.000 0.976 0.024
E22.1 Hyperprolactinaemia
0.000 0.976 0.024
E83.8 Other disorders of mineral metabolism
0.000 0.976 0.024
E83.2 Disorders of zinc metabolism
0.000 0.976 0.024
E83.0 Disorders of copper metabolism
0.000 0.976 0.024
E89.1 Postprocedural hypoinsulinaemia
0.000 0.976 0.024
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.976 0.024
E73 Lactose intolerance
0.000 0.976 0.024
E89.5 Postprocedural testicular hypofunction
0.000 0.977 0.023
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.977 0.023
E27.1 Primary adrenocortical insufficiency
0.000 0.977 0.023
E27.5 Adrenomedullary hyperfunction
0.000 0.977 0.022
E27.0 Other adrenocortical overactivity
0.000 0.977 0.022
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.978 0.022
E88.2 Lipomatosis, not elsewhere classified
0.000 0.978 0.022
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.978 0.022
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.978 0.021
E88.8 Other specified metabolic disorders
0.000 0.979 0.021
Z09.2 Follow-up examination after chemotherapy for other conditions
0.000 0.979 0.021
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.979 0.020
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.979 0.020
E88.9 Metabolic disorder, unspecified
0.000 0.979 0.020
E72.0 Disorders of amino-acid transport
0.000 0.980 0.020
E89.3 Postprocedural hypopituitarism
0.000 0.980 0.020
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.980 0.020
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.980 0.019
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.980 0.019
E79.1 Lesch-Nyhan syndrome
0.000 0.980 0.019
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.980 0.019
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.980 0.019
E72.5 Disorders of glycine metabolism
0.000 0.980 0.019
E72.4 Disorders of ornithine metabolism
0.000 0.980 0.019
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.980 0.019
E72.2 Disorders of urea cycle metabolism
0.000 0.980 0.019
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.980 0.019
E88.3 Tumour lysis syndrome
0.000 0.980 0.019
E27.2 Addisonian crisis
0.000 0.981 0.019
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.981 0.019
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.981 0.019
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.981 0.019
E74.2 Disorders of galactose metabolism
0.000 0.981 0.019
E74.1 Disorders of fructose metabolism
0.000 0.981 0.019
E74.0 Glycogen storage disease
0.000 0.981 0.019
E89.4 Postprocedural ovarian failure
0.000 0.981 0.019
E34 Other endocrine disorders
0.001 0.981 0.018
E71.3 Disorders of fatty-acid metabolism
0.000 0.981 0.019
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.981 0.019
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.981 0.019
E71.0 Maple-syrup-urine disease
0.000 0.981 0.019
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.981 0.019
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.981 0.019
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.981 0.019
E76.2 Other mucopolysaccharidoses
0.000 0.981 0.019
E76.1 Mucopolysaccharidosis, type II
0.000 0.981 0.019
E76.0 Mucopolysaccharidosis, type I
0.000 0.981 0.019
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.981 0.019
E77.8 Other disorders of glycoprotein metabolism
0.000 0.981 0.019
E77.1 Defects in glycoprotein degradation
0.000 0.981 0.019
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.981 0.019
E10.5 With peripheral circulatory complications
0.000 0.981 0.019
C44.1 Skin of eyelid, including canthus
0.019 0.981 0.000
E85.8 Other amyloidosis
0.000 0.981 0.018
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.981 0.018
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.981 0.018
E70.2 Disorders of tyrosine metabolism
0.000 0.981 0.018
E70.1 Other hyperphenylalaninaemias
0.000 0.981 0.018
E70.0 Classical phenylketonuria
0.000 0.981 0.018
E85.4 Organ-limited amyloidosis
0.000 0.982 0.018
E65 Localised adiposity
0.000 0.982 0.018
E75.6 Lipid storage disorder, unspecified
0.000 0.982 0.018
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.982 0.018
E75.3 Sphingolipidosis, unspecified
0.000 0.982 0.018
E75.1 Other gangliosidosis
0.000 0.982 0.018
E75.0 GM2 gangliosidosis
0.000 0.982 0.018
E84.9 Cystic fibrosis, unspecified
0.000 0.982 0.018
L43 Lichen planus
0.000 0.982 0.018
E75.5 Other lipid storage disorders
0.000 0.982 0.018
E84.8 Cystic fibrosis with other manifestations
0.000 0.982 0.018
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.982 0.018
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.982 0.018
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.982 0.018
E27.9 Disorder of adrenal gland, unspecified
0.000 0.982 0.018
E70.3 Albinism
0.000 0.982 0.017
E75.2 Other sphingolipidosis
0.000 0.982 0.017
E73.8 Other lactose intolerance
0.000 0.983 0.017
E73.1 Secondary lactase deficiency
0.000 0.983 0.017
E73.0 Congenital lactase deficiency
0.000 0.983 0.017
E29.1 Testicular hypofunction
0.000 0.983 0.017
E66 Obesity
0.000 0.983 0.017
E20.9 Hypoparathyroidism, unspecified
0.001 0.983 0.016
E83.5 Disorders of calcium metabolism
0.000 0.983 0.017
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.983 0.017
E85.9 Amyloidosis, unspecified
0.000 0.983 0.017
E21.0 Primary hyperparathyroidism
0.000 0.984 0.016
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.984 0.016
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.984 0.015
E85.3 Secondary systemic amyloidosis
0.000 0.985 0.015
E73.9 Lactose intolerance, unspecified
0.000 0.985 0.015
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.985 0.015
E27.8 Other specified disorders of adrenal gland
0.000 0.985 0.015
E78.2 Mixed hyperlipidaemia
0.000 0.985 0.015
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.985 0.015
E34.5 Androgen resistance syndrome
0.001 0.986 0.013
E34.4 Constitutional tall stature
0.001 0.986 0.013
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.986 0.013
E34.1 Other hypersecretion of intestinal hormones
0.001 0.986 0.013
E78.4 Other hyperlipidaemia
0.000 0.986 0.014
L43.3 Subacute (active) lichen planus
0.000 0.987 0.013
L43.2 Lichenoid drug reaction
0.000 0.987 0.013
L43.1 Bullous lichen planus
0.000 0.987 0.013
L43.8 Other lichen planus
0.000 0.987 0.013
E34.3 Short stature, not elsewhere classified
0.001 0.987 0.012
E66.1 Drug-induced obesity
0.000 0.987 0.012
L43.0 Hypertrophic lichen planus
0.000 0.988 0.012
E10.3 With ophthalmic complications
0.000 0.988 0.012
E34.9 Endocrine disorder, unspecified
0.001 0.988 0.011
E78.1 Pure hyperglyceridaemia
0.000 0.988 0.012
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.000 0.989 0.011
S83.2 Tear of meniscus, current
0.000 0.989 0.011
E34.8 Other specified endocrine disorders
0.001 0.989 0.010
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.989 0.011
E78.3 Hyperchylomicronaemia
0.000 0.989 0.011
E66.0 Obesity due to excess calories
0.000 0.989 0.011
E78.6 Lipoprotein deficiency
0.000 0.990 0.010
O47.1 False labour at or after 37 completed weeks of gestation
0.010 0.990 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.000 0.990 0.010
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.000 0.990 0.010
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.000 0.990 0.009
E78.8 Other disorders of lipoprotein metabolism
0.000 0.991 0.009
E28.2 Polycystic ovarian syndrome
0.001 0.991 0.008
C43.7 Malignant melanoma of lower limb, including hip
0.009 0.991 0.000
O47.0 False labour before 37 completed weeks of gestation
0.009 0.991 0.000
C53.9 Cervix uteri, unspecified
0.000 0.991 0.009
M87.9 Osteonecrosis, unspecified
0.000 0.991 0.009
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.991 0.009
O47 False labour
0.008 0.992 0.000
E80.5 Crigler-Najjar syndrome
0.000 0.992 0.008
E80.3 Defects of catalase and peroxydase
0.000 0.992 0.008
E80.0 Hereditary erythropoietic porphyria
0.000 0.992 0.008
M87.2 Osteonecrosis due to previous trauma
0.000 0.992 0.008
H54.0 Blindness, both eyes
0.008 0.992 0.000
S83.3 Tear of articular cartilage of knee, current
0.000 0.992 0.008
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.992 0.007
E80.2 Other porphyria
0.000 0.992 0.007
M87 Osteonecrosis
0.000 0.992 0.008
E80.6 Other disorders of bilirubin metabolism
0.000 0.992 0.007
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.000 0.992 0.007
E34.0 Carcinoid syndrome
0.002 0.993 0.006
E80.1 Porphyria cutanea tarda
0.000 0.993 0.007
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.007 0.993 0.000
E55.9 Vitamin D deficiency, unspecified
0.001 0.993 0.006
S83.7 Injury to multiple structures of knee
0.000 0.993 0.007
M87.8 Other osteonecrosis
0.000 0.993 0.007
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.007 0.993 0.000
S83.1 Dislocation of knee
0.000 0.993 0.006
O47.9 False labour, unspecified
0.007 0.993 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.000 0.993 0.006
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.000 0.993 0.006
M87.94 Osteonecrosis, unspecified (Hand)
0.000 0.993 0.006
M87.93 Osteonecrosis, unspecified (Forearm)
0.000 0.993 0.006
M87.92 Osteonecrosis, unspecified (Upper arm)
0.000 0.993 0.006
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.000 0.993 0.006
M87.85 Other osteonecrosis (Pelvic region and thigh)
0.000 0.994 0.006
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.006 0.994 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.000 0.994 0.006
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.000 0.994 0.006
M87.28 Osteonecrosis due to previous trauma (Other)
0.000 0.994 0.006
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.000 0.994 0.006
M87.24 Osteonecrosis due to previous trauma (Hand)
0.000 0.994 0.006
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.000 0.994 0.006
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.000 0.994 0.006
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.000 0.994 0.006
M87.98 Osteonecrosis, unspecified (Other)
0.000 0.994 0.006
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.000 0.994 0.006
N30.1 Interstitial cystitis (chronic)
0.006 0.994 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.006 0.994 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.006 0.994 0.000
E66.8 Other obesity
0.000 0.994 0.006
M87.3 Other secondary osteonecrosis
0.000 0.994 0.006
S83.0 Dislocation of patella
0.000 0.994 0.006
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.000 0.994 0.006
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.006 0.994 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.006 0.994 0.000
M87.1 Osteonecrosis due to drugs
0.000 0.994 0.005
M87.96 Osteonecrosis, unspecified (Lower leg)
0.000 0.994 0.005
M87.0 Idiopathic aseptic necrosis of bone
0.000 0.995 0.005
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.995 0.005
M87.89 Other osteonecrosis (Site unspecified)
0.000 0.995 0.005
M87.88 Other osteonecrosis (Other)
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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