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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs406936
log Bayes Factor = 39.5422
Chromosome 6   position 31,933,161  (GRCh37) Explore rs406936 on Ensembl!
Variant rs406936 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.001 0.999
E10.3 With ophthalmic complications
0.000 0.001 0.999
M06 Other rheumatoid arthritis
0.000 0.002 0.998
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
E10.1 With ketoacidosis
0.000 0.008 0.992
E05.9 Thyrotoxicosis, unspecified
0.000 0.012 0.988
E11.3 With ophthalmic complications
0.000 0.014 0.986
M05-M14 Inflammatory polyarthropathies
0.000 0.024 0.976
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.029 0.971
M06.0 Seronegative rheumatoid arthritis
0.000 0.034 0.966
M05 Seropositive rheumatoid arthritis
0.000 0.041 0.959
E65-E68 Obesity and other hyperalimentation
0.000 0.041 0.959
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.052 0.948
E10.5 With peripheral circulatory complications
0.000 0.060 0.940
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.068 0.932
E66 Obesity
0.000 0.071 0.929
E66.8 Other obesity
0.000 0.073 0.927
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.075 0.925
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.098 0.902
E11.5 With peripheral circulatory complications
0.000 0.100 0.900
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.100 0.900
E10.4 With neurological complications
0.000 0.119 0.881
L20-L30 Dermatitis and eczema
0.000 0.125 0.875
E10.2 With renal complications
0.000 0.128 0.872
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.129 0.871
E14 Unspecified diabetes mellitus
0.000 0.132 0.868
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.132 0.868
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.133 0.867
E11.9 Without complications
0.000 0.134 0.866
L27 Dermatitis due to substances taken internally
0.000 0.139 0.861
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.146 0.854
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.150 0.850
L40-L45 Papulosquamous disorders
0.000 0.151 0.849
M06.3 Rheumatoid nodule
0.000 0.159 0.841
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.162 0.838
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.167 0.833
L40 Psoriasis
0.000 0.171 0.829
E11.2 With renal complications
0.000 0.171 0.829
L29 Pruritus
0.000 0.174 0.826
L30 Other dermatitis
0.000 0.175 0.825
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.178 0.822
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.192 0.808
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.196 0.804
M07 Psoriatic and enteropathic arthropathies
0.000 0.197 0.803
L30.9 Dermatitis, unspecified
0.000 0.201 0.799
L40.5 Arthropathic psoriasis
0.000 0.206 0.794
M35 Other systemic involvement of connective tissue
0.000 0.207 0.793
M35.3 Polymyalgia rheumatica
0.000 0.208 0.792
E06 Thyroiditis
0.000 0.215 0.785
L29.0 Pruritus ani
0.000 0.216 0.784
M35.0 Sicca syndrome [Sjogren]
0.000 0.217 0.783
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.217 0.783
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.223 0.777
E14.9 Without complications
0.000 0.228 0.772
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.228 0.772
E10.6 With other specified complications
0.000 0.246 0.754
L57.0 Actinic keratosis
0.000 0.246 0.754
M14 Arthropathies in other diseases classified elsewhere
0.000 0.247 0.753
H36.0 Diabetic retinopathy
0.000 0.261 0.739
E10.8 With unspecified complications
0.000 0.262 0.738
M10 Gout
0.000 0.273 0.727
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.275 0.725
E14.3 With ophthalmic complications
0.000 0.277 0.723
L08 Other local infections of skin and subcutaneous tissue
0.000 0.277 0.723
L21 Seborrhoeic dermatitis
0.000 0.277 0.722
E10.7 With multiple complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E11.1 With ketoacidosis
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E05.5 Thyroid crisis or storm
0.000 0.284 0.716
E05.4 Thyrotoxicosis factitia
0.000 0.284 0.716
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.284 0.716
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.284 0.716
L40.0 Psoriasis vulgaris
0.000 0.284 0.716
M06.8 Other specified rheumatoid arthritis
0.000 0.285 0.715
M06.2 Rheumatoid bursitis
0.000 0.285 0.715
M06.1 Adult-onset Still's disease
0.000 0.285 0.715
E11.7 With multiple complications
0.000 0.285 0.715
E11.4 With neurological complications
0.000 0.286 0.714
L43 Lichen planus
0.000 0.292 0.708
E11.8 With unspecified complications
0.000 0.294 0.706
M06.34 Rheumatoid nodule (Hand)
0.000 0.299 0.701
M12 Other specific arthropathies
0.000 0.300 0.700
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.300 0.700
M08 Juvenile arthritis
0.000 0.300 0.700
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.300 0.700
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.308 0.692
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.308 0.692
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.308 0.692
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.308 0.692
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.308 0.692
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.308 0.692
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.308 0.692
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.308 0.692
E05.8 Other thyrotoxicosis
0.000 0.312 0.688
M05.8 Other seropositive rheumatoid arthritis
0.000 0.312 0.688
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.312 0.688
M05.2 Rheumatoid vasculitis
0.000 0.312 0.688
M05.1 Rheumatoid lung disease
0.000 0.312 0.688
M05.0 Felty's syndrome
0.000 0.312 0.688
E67 Other hyperalimentation
0.000 0.313 0.687
E68 Sequelae of hyperalimentation
0.000 0.313 0.687
E65 Localised adiposity
0.000 0.314 0.686
E20-E35 Disorders of other endocrine glands
0.000 0.320 0.680
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.320 0.680
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.320 0.680
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.320 0.680
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.320 0.680
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.320 0.680
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.320 0.680
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.320 0.680
M07.3 Other psoriatic arthropathies
0.000 0.320 0.680
M35.1 Other overlap syndromes
0.000 0.324 0.676
D64.9 Anaemia, unspecified
0.000 0.325 0.675
M35.7 Hypermobility syndrome
0.000 0.326 0.673
M06.4 Inflammatory polyarthropathy
0.000 0.327 0.673
E27 Other disorders of adrenal gland
0.000 0.329 0.671
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.330 0.670
E11.0 With coma
0.000 0.333 0.667
E66.1 Drug-induced obesity
0.000 0.334 0.666
M20-M25 Other joint disorders
0.000 0.334 0.666
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.334 0.666
D64 Other anaemias
0.000 0.337 0.663
E06.3 Autoimmune thyroiditis
0.000 0.343 0.657
D60-D64 Aplastic and other anaemias
0.000 0.344 0.656
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.345 0.655
# Top node
0.000 0.345 0.655
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.348 0.652
E11.6 With other specified complications
0.000 0.349 0.651
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.349 0.651
E27.1 Primary adrenocortical insufficiency
0.000 0.350 0.650
L29.8 Other pruritus
0.000 0.363 0.637
H36 Retinal disorders in diseases classified elsewhere
0.000 0.367 0.633
E50-E64 Other nutritional deficiencies
0.000 0.369 0.631
L25 Unspecified contact dermatitis
0.000 0.372 0.627
L24 Irritant contact dermatitis
0.000 0.372 0.627
L26 Exfoliative dermatitis
0.000 0.372 0.627
L22 Diaper [napkin] dermatitis
0.000 0.372 0.627
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.373 0.627
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.374 0.626
L20 Atopic dermatitis
0.000 0.375 0.625
E66.0 Obesity due to excess calories
0.000 0.376 0.623
E14.8 With unspecified complications
0.000 0.377 0.623
E14.7 With multiple complications
0.000 0.377 0.623
E14.6 With other specified complications
0.000 0.377 0.623
E14.5 With peripheral circulatory complications
0.000 0.377 0.623
E14.1 With ketoacidosis
0.000 0.377 0.623
E14.0 With coma
0.000 0.377 0.623
M13 Other arthritis
0.000 0.378 0.622
E13 Other specified diabetes mellitus
0.000 0.380 0.620
E40-E46 Malnutrition
0.000 0.381 0.619
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.382 0.617
L27.8 Dermatitis due to other substances taken internally
0.000 0.382 0.617
L27.2 Dermatitis due to ingested food
0.000 0.382 0.617
L40.8 Other psoriasis
0.000 0.383 0.617
L21.9 Seborrhoeic dermatitis, unspecified
0.000 0.387 0.613
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.388 0.612
M34 Systemic sclerosis
0.000 0.388 0.612
L29.9 Pruritus, unspecified
0.000 0.391 0.609
L44 Other papulosquamous disorders
0.000 0.391 0.609
L41 Parapsoriasis
0.000 0.391 0.609
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.391 0.609
L40.9 Psoriasis, unspecified
0.000 0.391 0.609
L50-L54 Urticaria and erythema
0.000 0.391 0.609
M22 Disorders of patella
0.000 0.395 0.605
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.397 0.603
M06.38 Rheumatoid nodule (Other)
0.000 0.397 0.603
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.397 0.603
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.397 0.603
M06.33 Rheumatoid nodule (Forearm)
0.000 0.397 0.603
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.397 0.603
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.397 0.603
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.397 0.603
L10-L14 Bullous disorders
0.000 0.399 0.601
L40.4 Guttate psoriasis
0.000 0.405 0.595
L40.3 Pustulosis palmaris et plantaris
0.000 0.405 0.595
L40.2 Acrodermatitis continua
0.000 0.405 0.595
L40.1 Generalised pustular psoriasis
0.000 0.405 0.595
D50-D53 Nutritional anaemias
0.000 0.406 0.594
M14.6 Neuropathic arthropathy
0.000 0.406 0.594
L23 Allergic contact dermatitis
0.000 0.407 0.593
L43.8 Other lichen planus
0.000 0.407 0.593
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.407 0.593
L29.3 Anogenital pruritus, unspecified
0.000 0.408 0.592
L29.1 Pruritus scroti
0.000 0.408 0.592
L30.5 Pityriasis alba
0.000 0.408 0.592
L30.4 Erythema intertrigo
0.000 0.408 0.592
L30.3 Infective dermatitis
0.000 0.408 0.592
L30.2 Cutaneous autosensitisation
0.000 0.408 0.592
L30.1 Dyshidrosis [pompholyx]
0.000 0.408 0.592
L30.0 Nummular dermatitis
0.000 0.408 0.592
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.411 0.589
L58 Radiodermatitis
0.000 0.411 0.589
L55 Sunburn
0.000 0.411 0.589
M11 Other crystal arthropathies
0.000 0.414 0.586
E14.4 With neurological complications
0.000 0.415 0.585
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.419 0.581
M10.9 Gout, unspecified
0.000 0.419 0.581
L28 Lichen simplex chronicus and prurigo
0.000 0.421 0.579
L42 Pityriasis rosea
0.000 0.421 0.579
M07.6 Other enteropathic arthropathies
0.000 0.424 0.576
M07.5 Arthropathy in ulcerative colitis
0.000 0.424 0.576
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.424 0.576
M07.2 Psoriatic spondylitis
0.000 0.424 0.576
M07.1 Arthritis mutilans
0.000 0.424 0.576
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.424 0.576
E20 Hypoparathyroidism
0.000 0.425 0.575
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.431 0.568
M35.8 Other specified systemic involvement of connective tissue
0.000 0.431 0.568
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.431 0.568
M35.5 Multifocal fibrosclerosis
0.000 0.431 0.568
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.431 0.568
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.433 0.567
M31 Other necrotising vasculopathies
0.000 0.437 0.563
E06.5 Other chronic thyroiditis
0.000 0.437 0.563
E06.4 Drug-induced thyroiditis
0.000 0.437 0.563
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.437 0.563
E06.1 Subacute thyroiditis
0.000 0.437 0.563
E06.0 Acute thyroiditis
0.000 0.437 0.563
E27.8 Other specified disorders of adrenal gland
0.000 0.438 0.562
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.438 0.561
L57.5 Actinic granuloma
0.000 0.438 0.561
L57.3 Poikiloderma of Civatte
0.000 0.438 0.561
L57.2 Cutis rhomboidalis nuchae
0.000 0.438 0.561
L57.1 Actinic reticuloid
0.000 0.438 0.561
L29.2 Pruritus vulvae
0.000 0.441 0.559
L01 Impetigo
0.000 0.443 0.557
L00 Staphylococcal scalded skin syndrome
0.000 0.443 0.557
H30-H36 Disorders of choroid and retina
0.000 0.443 0.557
D61 Other aplastic anaemias
0.000 0.444 0.556
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.446 0.554
E27.2 Addisonian crisis
0.000 0.446 0.554
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.449 0.551
M13.0 Polyarthritis, unspecified
0.000 0.451 0.549
M22.2 Patellofemoral disorders
0.000 0.451 0.549
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.453 0.546
M14.8 Arthropathies in other specified diseases classified elsewhere
0.000 0.460 0.540
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.000 0.460 0.540
M14.4 Arthropathy in amyloidosis
0.000 0.460 0.540
M14.3 Lipoid dermatoarthritis
0.000 0.460 0.540
M14.2 Diabetic arthropathy
0.000 0.460 0.540
M14.1 Crystal arthropathy in other metabolic disorders
0.000 0.460 0.540
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.000 0.460 0.540
L57.4 Cutis laxa senilis
0.000 0.462 0.538
L27.1 Localised skin eruption due to drugs and medicaments
0.000 0.466 0.534
M34.1 CR(E)ST syndrome
0.000 0.467 0.533
L43.9 Lichen planus, unspecified
0.000 0.468 0.532
Chapter VII Diseases of the eye and adnexa
0.000 0.470 0.530
E16 Other disorders of pancreatic internal secretion
0.000 0.472 0.528
E04 Other non-toxic goitre
0.000 0.474 0.526
M35.2 Behcet's disease
0.000 0.477 0.523
M10.4 Other secondary gout
0.000 0.478 0.522
M10.3 Gout due to impairment of renal function
0.000 0.478 0.522
M10.2 Drug-induced gout
0.000 0.478 0.522
M10.1 Lead-induced gout
0.000 0.478 0.522
M31.3 Wegener's granulomatosis
0.000 0.479 0.521
L04 Acute lymphadenitis
0.000 0.480 0.520
E15 Nondiabetic hypoglycaemic coma
0.000 0.480 0.520
D51 Vitamin B12 deficiency anaemia
0.000 0.480 0.520
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.481 0.519
E06.9 Thyroiditis, unspecified
0.000 0.482 0.518
L08.1 Erythrasma
0.000 0.482 0.518
L08.0 Pyoderma
0.000 0.482 0.518
L21.8 Other seborrhoeic dermatitis
0.000 0.482 0.518
L21.1 Seborrhoeic infantile dermatitis
0.000 0.482 0.518
L21.0 Seborrhoea capitis
0.000 0.482 0.518
L30.8 Other specified dermatitis
0.000 0.484 0.516
E14.2 Withrenal complications
0.000 0.485 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M13.00 Polyarthritis, unspecified (Multiple sites)
0.000 0.486 0.514
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.487 0.513
M06.18 Adult-onset Still's disease (Other)
0.000 0.487 0.513
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.487 0.513
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.487 0.513
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.487 0.513
M06.14 Adult-onset Still's disease (Hand)
0.000 0.487 0.513
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.487 0.513
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.487 0.513
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.487 0.513
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.487 0.513
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.487 0.513
M06.28 Rheumatoid bursitis (Other)
0.000 0.487 0.513
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.487 0.513
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.487 0.513
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.487 0.513
M06.24 Rheumatoid bursitis (Hand)
0.000 0.487 0.513
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.487 0.513
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.487 0.513
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.487 0.513
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.487 0.513
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.487 0.513
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.487 0.513
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.487 0.513
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.487 0.513
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.487 0.513
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.487 0.513
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.487 0.513
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.487 0.513
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.487 0.513
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.487 0.513
M34.9 Systemic sclerosis, unspecified
0.000 0.490 0.510
L43.3 Subacute (active) lichen planus
0.000 0.492 0.508
L43.2 Lichenoid drug reaction
0.000 0.492 0.508
L43.1 Bullous lichen planus
0.000 0.492 0.508
L43.0 Hypertrophic lichen planus
0.000 0.492 0.508
M08.9 Juvenile arthritis, unspecified
0.000 0.498 0.502
M08.8 Other juvenile arthritis
0.000 0.498 0.502
M08.4 Pauciarticular juvenile arthritis
0.000 0.498 0.502
M08.3 Juvenile polyarthritis (seronegative)
0.000 0.498 0.502
M08.2 Juvenile arthritis with systemic onset
0.000 0.498 0.502
M08.1 Juvenile ankylosing spondylitis
0.000 0.498 0.502
M08.0 Juvenile rheumatoid arthritis
0.000 0.498 0.502
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.000 0.498 0.502
M09.2 Juvenile arthritis in ulcerative colitis
0.000 0.498 0.502
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.000 0.498 0.502
M09.0 Juvenile arthritis in psoriasis
0.000 0.498 0.502
M12.8 Other specific arthropathies, not elsewhere classified
0.000 0.498 0.502
M12.5 Traumatic arthropathy
0.000 0.498 0.502
M12.4 Intermittent hydrarthrosis
0.000 0.498 0.502
M12.3 Palindromic rheumatism
0.000 0.498 0.502
M12.2 Villonodular synovitis (pigmented)
0.000 0.498 0.502
M12.1 Kaschin-Beck disease
0.000 0.498 0.502
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.000 0.498 0.502
L50 Urticaria
0.000 0.499 0.501
M30 Polyarteritis nodosa and related conditions
0.000 0.499 0.501
M10.97 Gout, unspecified (Ankle and foot)
0.000 0.500 0.500
E07 Other disorders of thyroid
0.000 0.500 0.500
E20.9 Hypoparathyroidism, unspecified
0.000 0.500 0.499
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.501 0.498
D50 Iron deficiency anaemia
0.000 0.504 0.496
Chapter VI Diseases of the nervous system
0.000 0.506 0.494
M05.09 Felty's syndrome (Site unspecified)
0.000 0.507 0.493
M05.08 Felty's syndrome (Other)
0.000 0.507 0.493
M05.07 Felty's syndrome (Ankle and foot)
0.000 0.507 0.493
M05.06 Felty's syndrome (Lower leg)
0.000 0.507 0.493
M05.05 Felty's syndrome (Pelvic region and thigh)
0.000 0.507 0.493
M05.04 Felty's syndrome (Hand)
0.000 0.507 0.493
M05.03 Felty's syndrome (Forearm)
0.000 0.507 0.493
M05.02 Felty's syndrome (Upper arm)
0.000 0.507 0.493
M05.01 Felty's syndrome (Shoulder region)
0.000 0.507 0.493
M05.00 Felty's syndrome (Multiple sites)
0.000 0.507 0.493
M05.19 Rheumatoid lung disease (Site unspecified)
0.000 0.507 0.493
M05.18 Rheumatoid lung disease (Other)
0.000 0.507 0.493
M05.17 Rheumatoid lung disease (Ankle and foot)
0.000 0.507 0.493
M05.16 Rheumatoid lung disease (Lower leg)
0.000 0.507 0.493
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.000 0.507 0.493
M05.14 Rheumatoid lung disease (Hand)
0.000 0.507 0.493
M05.13 Rheumatoid lung disease (Forearm)
0.000 0.507 0.493
M05.12 Rheumatoid lung disease (Upper arm)
0.000 0.507 0.493
M05.11 Rheumatoid lung disease (Shoulder region)
0.000 0.507 0.493
M05.10 Rheumatoid lung disease (Multiple sites)
0.000 0.507 0.493
M05.29 Rheumatoid vasculitis (Site unspecified)
0.000 0.507 0.493
M05.28 Rheumatoid vasculitis (Other)
0.000 0.507 0.493
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.000 0.507 0.493
M05.26 Rheumatoid vasculitis (Lower leg)
0.000 0.507 0.493
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.000 0.507 0.493
M05.24 Rheumatoid vasculitis (Hand)
0.000 0.507 0.493
M05.23 Rheumatoid vasculitis (Forearm)
0.000 0.507 0.493
M05.22 Rheumatoid vasculitis (Upper arm)
0.000 0.507 0.493
M05.21 Rheumatoid vasculitis (Shoulder region)
0.000 0.507 0.493
M05.20 Rheumatoid vasculitis (Multiple sites)
0.000 0.507 0.493
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.000 0.507 0.493
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.000 0.507 0.493
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.000 0.507 0.493
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.000 0.507 0.493
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.000 0.507 0.493
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.000 0.507 0.493
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.000 0.507 0.493
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.000 0.507 0.493
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.000 0.507 0.493
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.000 0.507 0.493
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.000 0.507 0.493
M05.88 Other seropositive rheumatoid arthritis (Other)
0.000 0.507 0.493
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.000 0.507 0.493
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.000 0.507 0.493
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.000 0.507 0.493
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.000 0.507 0.493
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.000 0.507 0.493
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.000 0.507 0.493
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.000 0.507 0.493
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.000 0.507 0.493
E67.8 Other specified hyperalimentation
0.000 0.507 0.493
E67.3 Hypervitaminosis D
0.000 0.507 0.493
E67.2 Megavitamin-B6 syndrome
0.000 0.507 0.493
E67.1 Hypercarotenaemia
0.000 0.507 0.493
E67.0 Hypervitaminosis A
0.000 0.507 0.493
M33 Dermatopolymyositis
0.000 0.509 0.490
M22.3 Other derangements of patella
0.000 0.510 0.490
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.512 0.488
E32 Diseases of thymus
0.000 0.512 0.488
E31 Polyglandular dysfunction
0.000 0.512 0.488
E30 Disorders of puberty, not elsewhere classified
0.000 0.512 0.488
M07.38 Other psoriatic arthropathies (Other)
0.000 0.513 0.487
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.513 0.487
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.513 0.487
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.513 0.487
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.513 0.487
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.513 0.487
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.513 0.487
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.514 0.486
D61.9 Aplastic anaemia, unspecified
0.000 0.516 0.484
H35 Other retinal disorders
0.000 0.517 0.483
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.517 0.482
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.517 0.482
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.517 0.482
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.517 0.482
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.517 0.482
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.517 0.482
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.517 0.482
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.517 0.482
L80-L99 Other disorders of the skin and subcutaneous tissue
0.000 0.518 0.482
E27.5 Adrenomedullary hyperfunction
0.000 0.519 0.481
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.519 0.481
E27.0 Other adrenocortical overactivity
0.000 0.519 0.481
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.520 0.480
M10.90 Gout, unspecified (Multiple sites)
0.000 0.520 0.480
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.522 0.478
M10.0 Idiopathic gout
0.000 0.522 0.477
G90-G99 Other disorders of the nervous system
0.000 0.523 0.477
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.524 0.476
D64.4 Congenital dyserythropoietic anaemia
0.000 0.524 0.476
D64.3 Other sideroblastic anaemias
0.000 0.524 0.476
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.000 0.524 0.476
D64.1 Secondary sideroblastic anaemia due to disease
0.000 0.524 0.476
D64.0 Hereditary sideroblastic anaemia
0.000 0.524 0.476
M32 Systemic lupus erythematosus
0.000 0.526 0.474
E28 Ovarian dysfunction
0.000 0.526 0.474
E03.8 Other specified hypothyroidism
0.001 0.527 0.473
G91 Hydrocephalus
0.000 0.528 0.472
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.000 0.530 0.470
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.530 0.469
D64.8 Other specified anaemias
0.000 0.531 0.469
M34.8 Other forms of systemic sclerosis
0.000 0.532 0.468
G91.9 Hydrocephalus, unspecified
0.000 0.533 0.467
M10.96 Gout, unspecified (Lower leg)
0.000 0.534 0.466
H35.3 Degeneration of macula and posterior pole
0.000 0.537 0.463
D50.9 Iron deficiency anaemia, unspecified
0.000 0.537 0.463
L05 Pilonidal cyst
0.000 0.538 0.462
L03 Cellulitis
0.000 0.538 0.462
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.546 0.454
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.548 0.452
E63 Other nutritional deficiencies
0.000 0.548 0.452
E56 Other vitamin deficiencies
0.000 0.548 0.452
E51 Thiamine deficiency
0.000 0.548 0.452
E50 Vitamin A deficiency
0.000 0.548 0.452
E60 Dietary zinc deficiency
0.000 0.548 0.452
E59 Dietary selenium deficiency
0.000 0.548 0.452
E58 Dietary calcium deficiency
0.000 0.548 0.452
E54 Ascorbic acid deficiency
0.000 0.548 0.452
E52 Niacin deficiency [pellagra]
0.000 0.548 0.452
L24.9 Irritant contact dermatitis, unspecified cause
0.000 0.550 0.450
L24.8 Irritant contact dermatitis due to other agents
0.000 0.550 0.450
L24.7 Irritant contact dermatitis due to plants, except food
0.000 0.550 0.450
L24.6 Irritant contact dermatitis due to food in contact with the skin
0.000 0.550 0.450
L24.5 Irritant contact dermatitis due to other chemical products
0.000 0.550 0.450
L24.4 Irritant contact dermatitis due to drugs in contact with the skin
0.000 0.550 0.450
L24.3 Irritant contact dermatitis due to cosmetics
0.000 0.550 0.450
L24.2 Irritant contact dermatitis due to solvents
0.000 0.550 0.450
L24.1 Irritant contact dermatitis due to oils and greases
0.000 0.550 0.450
L24.0 Irritant contact dermatitis due to detergents
0.000 0.550 0.450
L25.9 Unspecified contact dermatitis, unspecified cause
0.000 0.550 0.450
L25.8 Unspecified contact dermatitis due to other agents
0.000 0.550 0.450
L25.5 Unspecified contact dermatitis due to plants, except food
0.000 0.550 0.450
L25.4 Unspecified contact dermatitis due to food in contact with the skin
0.000 0.550 0.450
L25.3 Unspecified contact dermatitis due to other chemical products
0.000 0.550 0.450

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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