TreeWAS – Variant ID: rs4074793

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20.0 Unstable angina	0.178	0.822	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.925	0.075
K25 Gastric ulcer	0.000	0.964	0.036
K25.7 Chronic without haemorrhage or perforation	0.000	0.967	0.033
E78.0 Pure hypercholesterolaemia	0.031	0.969	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.974	0.026
K25.2 Acute with both haemorrhage and perforation	0.000	0.974	0.026
K25.1 Acute with perforation	0.000	0.974	0.026
K25.0 Acute with haemorrhage	0.000	0.974	0.026
K25.4 Chronic or unspecified with haemorrhage	0.000	0.975	0.025
K25.3 Acute without haemorrhage or perforation	0.000	0.976	0.023
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.977	0.023
C44.5 Skin of trunk	0.000	0.978	0.022
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.022	0.978	0.000
C44.7 Skin of lower limb, including hip	0.000	0.979	0.021
R26 Abnormalities of gait and mobility	0.000	0.980	0.020
K25.5 Chronic or unspecified with perforation	0.000	0.980	0.020
E78.1 Pure hyperglyceridaemia	0.020	0.980	0.000
E78.8 Other disorders of lipoprotein metabolism	0.019	0.981	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.981	0.019
E78.6 Lipoprotein deficiency	0.018	0.982	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.018	0.982	0.000
E78.2 Mixed hyperlipidaemia	0.017	0.983	0.000
E78.3 Hyperchylomicronaemia	0.016	0.984	0.000
R26.3 Immobility	0.000	0.985	0.015
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.000	0.985	0.015
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.985	0.015
E78.4 Other hyperlipidaemia	0.015	0.985	0.000
R26.1 Paralytic gait	0.000	0.985	0.015
C44 Other malignant neoplasms of skin	0.000	0.985	0.015
R25 Abnormal involuntary movements	0.000	0.985	0.015
R26.0 Ataxic gait	0.000	0.985	0.014
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.986	0.014
I20 Angina pectoris	0.014	0.986	0.000
R27 Other lack of coordination	0.000	0.987	0.013
C44.0 Skin of lip	0.000	0.988	0.012
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.988	0.012
R27.0 Ataxia, unspecified	0.000	0.988	0.012
Y83.8 Other surgical procedures	0.000	0.988	0.012
R25.3 Fasciculation	0.000	0.989	0.011
S82.10 Fracture of upper end of tibia (closed)	0.000	0.989	0.011
C44.8 Overlapping lesion of skin	0.000	0.989	0.011
R25.1 Tremor, unspecified	0.000	0.989	0.011
R25.0 Abnormal head movements	0.000	0.989	0.011
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.989	0.011
R25.2 Cramp and spasm	0.000	0.989	0.011
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.991	0.009
S82.1 Fracture of upper end of tibia	0.000	0.991	0.009
R27.8 Other and unspecified lack of coordination	0.000	0.991	0.009
Z72.0 Tobacco use	0.009	0.991	0.000
I20.1 Angina pectoris with documented spasm	0.009	0.991	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.992	0.008
C44.6 Skin of upper limb, including shoulder	0.000	0.992	0.008
S82.8 Fractures of other parts of lower leg	0.000	0.992	0.008
S82 Fracture of lower leg, including ankle	0.000	0.992	0.008
R29.6 Tendency to fall, not elsewhere classified	0.000	0.992	0.008
S82.5 Fracture of medial malleolus	0.000	0.993	0.007
S82.50 Fracture of medial malleolus (closed)	0.000	0.993	0.007
G40.9 Epilepsy, unspecified	0.000	0.993	0.007
S82.4 Fracture of fibula alone	0.000	0.993	0.007
R29.4 Clicking hip	0.000	0.993	0.007
R29.3 Abnormal posture	0.000	0.993	0.007
R29.2 Abnormal reflex	0.000	0.993	0.007
R29.1 Meningismus	0.000	0.993	0.007
R29.0 Tetany	0.000	0.993	0.007
S82.11 Fracture of upper end of tibia (open)	0.000	0.993	0.007
C44.3 Skin of other and unspecified parts of face	0.000	0.993	0.007
S82.40 Fracture of fibula alone (closed)	0.000	0.993	0.007
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.994	0.006
C44.4 Skin of scalp and neck	0.000	0.994	0.006
N40 Hyperplasia of prostate	0.000	0.994	0.006
N80.1 Endometriosis of ovary	0.006	0.994	0.000
S82.9 Fracture of lower leg, part unspecified	0.000	0.994	0.006
S82.7 Multiple fractures of lower leg	0.000	0.994	0.006
S82.86 Maisonneuve's fracture	0.000	0.994	0.006
A41.9 Septicaemia, unspecified	0.000	0.994	0.006
S82.3 Fracture of lower end of tibia	0.000	0.994	0.006
N93 Other abnormal uterine and vaginal bleeding	0.000	0.994	0.006
S82.51 Fracture of medial malleolus (open)	0.000	0.994	0.005
N80.3 Endometriosis of pelvic peritoneum	0.006	0.994	0.000
E11.9 Without complications	0.006	0.994	0.000
S82.41 Fracture of fibula alone (open)	0.000	0.995	0.005
I20.8 Other forms of angina pectoris	0.005	0.995	0.000
S82.0 Fracture of patella	0.000	0.995	0.005
S82.81 Fractures of other parts of lower leg (open)	0.000	0.995	0.005
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.995	0.005
N80 Endometriosis	0.005	0.995	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.995	0.005
C43 Malignant melanoma of skin	0.000	0.995	0.005
S82.6 Fracture of lateral malleolus	0.000	0.995	0.004
S82.71 Multiple fractures of lower leg (open)	0.000	0.995	0.004
S82.70 Multiple fractures of lower leg (closed)	0.000	0.995	0.004
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.995	0.004
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.995	0.004
S82.31 Fracture of lower end of tibia (open)	0.000	0.995	0.004
A41 Other septicaemia	0.000	0.995	0.004
S82.2 Fracture of shaft of tibia	0.000	0.996	0.004
C44.2 Skin of ear and external auricular canal	0.000	0.996	0.004
N80.8 Other endometriosis	0.004	0.996	0.000
N60.3 Fibrosclerosis of breast	0.004	0.996	0.000
B07 Viral warts	0.004	0.996	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.996	0.004
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.996	0.004
N80.2 Endometriosis of Fallopian tube	0.004	0.996	0.000
S82.01 Fracture of patella (open)	0.000	0.996	0.004
N80.4 Endometriosis of rectovaginal septum and vagina	0.004	0.996	0.000
D25.1 Intramural leiomyoma of uterus	0.000	0.996	0.004
I84.5 External haemorrhoids without complication	0.000	0.996	0.004
N93.8 Other specified abnormal uterine and vaginal bleeding	0.000	0.996	0.004
I84.8 Unspecified haemorrhoids with other complications	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.004	0.996	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.996	0.004
D25 Leiomyoma of uterus	0.000	0.996	0.004
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.996	0.004
N80.9 Endometriosis, unspecified	0.004	0.996	0.000
N80.6 Endometriosis in cutaneous scar	0.004	0.996	0.000
N80.5 Endometriosis of intestine	0.004	0.996	0.000
N93.0 Postcoital and contact bleeding	0.000	0.996	0.004
F31 Bipolar affective disorder	0.004	0.996	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.996	0.004
Z72.2 Drug use	0.004	0.996	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.004	0.996	0.000
Z72 Problems related to lifestyle	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
C43.8 Overlapping malignant melanoma of skin	0.000	0.996	0.003
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.996	0.003
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.996	0.003
C43.0 Malignant melanoma of lip	0.000	0.996	0.003
D25.9 Leiomyoma of uterus, unspecified	0.000	0.996	0.004
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.996	0.004
R20.8 Other and unspecified disturbances of skin sensation	0.004	0.996	0.000
S82.61 Fracture of lateral malleolus (open)	0.000	0.996	0.003
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.003	0.996	0.000
A41.4 Septicaemia due to anaerobes	0.000	0.996	0.003
A41.3 Septicaemia due to Haemophilus influenzae	0.000	0.996	0.003
E78.5 Hyperlipidaemia, unspecified	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.000	0.997	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.003	0.997	0.000
H02.5 Other disorders affecting eyelid function	0.003	0.997	0.000
F31.9 Bipolar affective disorder, unspecified	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
S82.21 Fracture of shaft of tibia (open)	0.000	0.997	0.003
D25.0 Submucous leiomyoma of uterus	0.000	0.997	0.003
C43.9 Malignant melanoma of skin, unspecified	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.997	0.003
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.003	0.997	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.003	0.997	0.000
F31.8 Other bipolar affective disorders	0.003	0.997	0.000
F31.7 Bipolar affective disorder, currently in remission	0.003	0.997	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.003	0.997	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.997	0.003
M47.96 Spondylosis, unspecified (Lumbar region)	0.003	0.997	0.000
Z72.9 Problem related to lifestyle, unspecified	0.003	0.997	0.000
Z72.8 Other problems related to lifestyle	0.003	0.997	0.000
Z72.6 Gambling and betting	0.003	0.997	0.000
Z72.5 High-risk sexual behaviour	0.003	0.997	0.000
Z72.4 Inappropriate diet and eating habits	0.003	0.997	0.000
Z72.3 Lack of physical exercise	0.003	0.997	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
C43.4 Malignant melanoma of scalp and neck	0.000	0.997	0.003
Y45.0 Opioids and related analgesics	0.000	0.997	0.003
K70 Alcoholic liver disease	0.000	0.997	0.003
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.997	0.003
S89.9 Unspecified injury of lower leg	0.000	0.997	0.003
G61.0 Guillain-Barre syndrome	0.000	0.997	0.003
H91.9 Hearing loss, unspecified	0.003	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.997	0.003
I84.3 External thrombosed haemorrhoids	0.000	0.997	0.003
K70.0 Alcoholic fatty liver	0.000	0.997	0.002
S80-S89 Injuries to the knee and lower leg	0.000	0.998	0.002
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.998	0.002
K70.4 Alcoholic hepatic failure	0.000	0.998	0.002
C43.5 Malignant melanoma of trunk	0.000	0.998	0.002
H00.1 Chalazion	0.000	0.998	0.002
A41.8 Other specified septicaemia	0.000	0.998	0.002
S82.20 Fracture of shaft of tibia (closed)	0.000	0.998	0.002
I84.2 Internal haemorrhoids without complication	0.000	0.998	0.002
G50.0 Trigeminal neuralgia	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.002
I84 Haemorrhoids	0.000	0.998	0.002
S86 Injury of muscle and tendon at lower leg level	0.000	0.998	0.002
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.002	0.998	0.000
K70.1 Alcoholic hepatitis	0.000	0.998	0.002
S89.8 Other specified injuries of lower leg	0.000	0.998	0.002
S89.7 Multiple injuries of lower leg	0.000	0.998	0.002
S89.1 Other specified injuries of lower leg	0.000	0.998	0.002
S89.0 Multiple injuries of lower leg	0.000	0.998	0.002
N19 Unspecified renal failure	0.000	0.998	0.002
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
R20 Disturbances of skin sensation	0.002	0.998	0.000
S88 Traumatic amputation of lower leg	0.000	0.998	0.002
S87 Crushing injury of lower leg	0.000	0.998	0.002
S85 Injury of blood vessels at lower leg level	0.000	0.998	0.002
S84 Injury of nerves at lower leg level	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.002	0.998	0.000
B01 Varicella [chickenpox]	0.002	0.998	0.000
H74 Other disorders of middle ear and mastoid	0.002	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
B01.9 Varicella without complications	0.002	0.998	0.000
D12.2 Ascending colon	0.000	0.998	0.002
H91 Other hearing loss	0.002	0.998	0.000
B08.1 Molluscum contagiosum	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.002	0.998	0.000
F45.8 Other somatoform disorders	0.002	0.998	0.000
R20.0 Anaesthesia of skin	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
S86.0 Injury of Achilles tendon	0.000	0.998	0.002
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.998	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.998	0.002
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.002
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
B06 Rubella [German measles]	0.002	0.998	0.000
B05 Measles	0.002	0.998	0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.002	0.998	0.000
B04 Monkeypox	0.002	0.998	0.000
B03 Smallpox	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.002
H91.1 Presbycusis	0.002	0.998	0.000
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.998	0.002
S80 Superficial injury of lower leg	0.000	0.998	0.002
N18.5 Chronic kidney disease, stage 5	0.000	0.998	0.002
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.002
B00 Herpesviral [herpes simplex] infections	0.002	0.998	0.000
N81.4 Uterovaginal prolapse, unspecified	0.000	0.998	0.002
R20.2 Paraesthesia of skin	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.998	0.002
S80.0 Contusion of knee	0.000	0.998	0.002
N60 Benign mammary dysplasia	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.998	0.002
H74.9 Disorder of middle ear and mastoid, unspecified	0.002	0.998	0.000
R20.3 Hyperaesthesia	0.002	0.998	0.000
R20.1 Hypoaesthesia of skin	0.002	0.998	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.998	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.998	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.998	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.998	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.998	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.998	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.998	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.998	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.998	0.002
S85.5 Injury of popliteal vein	0.000	0.998	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.998	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.998	0.002
S85.2 Injury of peroneal artery	0.000	0.998	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.998	0.002
S85.0 Injury of popliteal artery	0.000	0.998	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.998	0.002
S87.0 Crushing injury of knee	0.000	0.998	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.998	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.998	0.002
S88.0 Traumatic amputation at knee level	0.000	0.998	0.002
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
B01.8 Varicella with other complications	0.002	0.998	0.000
B01.2 Varicella pneumonia	0.002	0.998	0.000
B01.1 Varicella encephalitis	0.002	0.998	0.000
B01.0 Varicella meningitis	0.002	0.998	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.998	0.002
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.998	0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
B00.5 Herpesviral ocular disease	0.002	0.998	0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.002	0.998	0.000
B08.5 Enteroviral vesicular pharyngitis	0.002	0.998	0.000
B08.4 Enteroviral vesicular stomatitis with exanthem	0.002	0.998	0.000
B08.3 Erythema infectiosum [fifth disease]	0.002	0.998	0.000
B08.2 Exanthema subitum [sixth disease]	0.002	0.998	0.000
B08.0 Other orthopoxvirus infections	0.002	0.998	0.000
H02.8 Other specified disorders of eyelid	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.998	0.002
H74.0 Tympanosclerosis	0.002	0.998	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
H02.3 Blepharochalasis	0.002	0.998	0.000
H91.8 Other specified hearing loss	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.001
B05.9 Measles without complication	0.001	0.998	0.000
B05.8 Measles with other complications	0.001	0.998	0.000
B05.4 Measles with intestinal complications	0.001	0.998	0.000
B05.3 Measles complicated by otitis media	0.001	0.998	0.000
B05.2 Measles complicated by pneumonia	0.001	0.998	0.000
B05.1 Measles complicated by meningitis	0.001	0.998	0.000
B05.0 Measles complicated by encephalitis	0.001	0.998	0.000
B06.9 Rubella without complication	0.001	0.998	0.000
B06.8 Rubella with other complications	0.001	0.998	0.000
B06.0 Rubella with neurological complications	0.001	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.998	0.001
G61.1 Serum neuropathy	0.000	0.998	0.001
K76.8 Other specified diseases of liver	0.000	0.998	0.002
N60.8 Other benign mammary dysplasias	0.002	0.998	0.000
B02 Zoster [herpes zoster]	0.002	0.998	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
H53.1 Subjective visual disturbances	0.000	0.998	0.002
B00.8 Other forms of herpesviral infection	0.001	0.998	0.000
B00.7 Disseminated herpesviral disease	0.001	0.998	0.000
B00.4 Herpesviral encephalitis	0.001	0.998	0.000
B00.3 Herpesviral meningitis	0.001	0.998	0.000
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.998	0.000
B00.0 Eczema herpeticum	0.001	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.001
H02 Other disorders of eyelid	0.002	0.998	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.998	0.001
N18.0 End-stage renal disease	0.000	0.998	0.002
N60.9 Benign mammary dysplasia, unspecified	0.001	0.998	0.000
N18 Chronic renal failure	0.000	0.998	0.002
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.001
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.998	0.000
C02.8 Overlapping lesion of tongue	0.001	0.998	0.000
C02.4 Lingual tonsil	0.001	0.998	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.001	0.998	0.000
C02.2 Ventral surface of tongue	0.001	0.998	0.000
C02.0 Dorsal surface of tongue	0.001	0.998	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.001	0.998	0.000
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
H74.4 Polyp of middle ear	0.001	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
Y45.1 Salicylates	0.000	0.998	0.001
O64 Obstructed labour due to malposition and malpresentation of foetus	0.001	0.998	0.000
I89.0 Lymphoedema, not elsewhere classified	0.000	0.998	0.001
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.998	0.002
L81.4 Other melanin hyperpigmentation	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.001
H72.8 Other perforations of tympanic membrane	0.001	0.998	0.000
I84.1 Internal haemorrhoids with other complications	0.000	0.998	0.001
I84.0 Internal thrombosed haemorrhoids	0.000	0.998	0.001
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.999	0.001
O63.1 Prolonged second stage (of labour)	0.001	0.999	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.999	0.001
H53.8 Other visual disturbances	0.000	0.999	0.001
O03.9 Complete or unspecified, without complication	0.000	0.999	0.001
R47.1 Dysarthria and anarthria	0.000	0.999	0.001
Z83.5 Family history of eye and ear disorders	0.000	0.999	0.001
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.999	0.001
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
B00.1 Herpesviral vesicular dermatitis	0.001	0.999	0.000
B02.8 Zoster with other complications	0.001	0.999	0.000
B02.7 Disseminated zoster	0.001	0.999	0.000
B02.1 Zoster meningitis	0.001	0.999	0.000
B02.0 Zoster encephalitis	0.001	0.999	0.000
N80.0 Endometriosis of uterus	0.001	0.999	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
C71.1 Frontal lobe	0.001	0.999	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.001	0.999	0.000
H02.6 Xanthelasma of eyelid	0.001	0.999	0.000
H02.2 Lagophthalmos	0.001	0.999	0.000
M16.1 Other primary coxarthrosis	0.001	0.999	0.000
O32.1 Maternal care for breech presentation	0.000	0.999	0.001
S80.9 Superficial injury of lower leg, unspecified	0.000	0.999	0.001
Z29.2 Other prophylactic chemotherapy	0.000	0.999	0.001
M24.07 Loose body in joint (Ankle and foot)	0.001	0.999	0.000
I87.8 Other specified disorders of veins	0.000	0.999	0.001
S83.7 Injury to multiple structures of knee	0.000	0.999	0.001
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.999	0.001
S83.3 Tear of articular cartilage of knee, current	0.000	0.999	0.001
S83.1 Dislocation of knee	0.000	0.999	0.001
S83.0 Dislocation of patella	0.000	0.999	0.001
Z97.4 Presence of external hearing-aid	0.000	0.999	0.001
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.999	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.999	0.000
B02.3 Zoster ocular disease	0.001	0.999	0.000
I22.8 Subsequent myocardial infarction of other sites	0.001	0.999	0.000
N60.0 Solitary cyst of breast	0.001	0.999	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.001	0.999	0.000
O64.5 Obstructed labour due to compound presentation	0.001	0.999	0.000
O64.4 Obstructed labour due to shoulder presentation	0.001	0.999	0.000
O64.3 Obstructed labour due to brow presentation	0.001	0.999	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.999	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.999	0.001
D48.5 Skin	0.001	0.999	0.000
O03.4 Incomplete, without complication	0.000	0.999	0.001
H66.2 Chronic atticoantral suppurative otitis media	0.001	0.999	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.999	0.001
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
N17-N19 Renal failure	0.000	0.999	0.001
C71.2 Temporal lobe	0.001	0.999	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.999	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.999	0.001
Y45.8 Other analgesics and antipyretics	0.000	0.999	0.001
Y45.5 4-Aminophenol derivatives	0.000	0.999	0.001
Y45.4 Antirheumatics	0.000	0.999	0.001
H70 Mastoiditis and related conditions	0.001	0.999	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.999	0.001
H72.9 Perforation of tympanic membrane, unspecified	0.001	0.999	0.000
N18.8 Other chronic renal failure	0.000	0.999	0.001
N18.1 Chronic kidney disease, stage 1	0.000	0.999	0.001
N60.4 Mammary duct ectasia	0.001	0.999	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.999	0.001
C04.9 Floor of mouth, unspecified	0.001	0.999	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
O62.3 Precipitate labour	0.001	0.999	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.001	0.999	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.999	0.001
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.999	0.001
O69.1 Labour and delivery complicated by cord around neck, with compression	0.001	0.999	0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.000	0.999	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.999	0.001
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
C71.0 Cerebrum, except lobes and ventricles	0.001	0.999	0.000
I84.4 External haemorrhoids with other complications	0.000	0.999	0.001
H69.0 Patulous Eustachian tube	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
N08.5 Glomerular disorders in systemic connective tissue disorders	0.000	0.999	0.001
O62.1 Secondary uterine inertia	0.001	0.999	0.000
A30-A49 Other bacterial diseases	0.000	0.999	0.001
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.001	0.999	0.000
C14.0 Pharynx, unspecified	0.001	0.999	0.000
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000
H70.2 Petrositis	0.001	0.999	0.000
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.001	0.999	0.000
O72.0 Third-stage haemorrhage	0.001	0.999	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.999	0.001
H00 Hordeolum and chalazion	0.000	0.999	0.001
H73 Other disorders of tympanic membrane	0.001	0.999	0.000
H66 Suppurative and unspecified otitis media	0.001	0.999	0.000
O03 Spontaneous abortion	0.000	0.999	0.001
R47 Speech disturbances, not elsewhere classified	0.000	0.999	0.001
I20-I25 Ischaemic heart diseases	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.001	0.999	0.000
O75.8 Other specified complications of labour and delivery	0.001	0.999	0.000
Y45.2 Propionic acid derivatives	0.000	0.999	0.001
C07 Malignant neoplasm of parotid gland	0.001	0.999	0.000
C71 Malignant neoplasm of brain	0.001	0.999	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.001	0.999	0.000
O62 Abnormalities of forces of labour	0.001	0.999	0.000
S81 Open wound of lower leg	0.000	0.999	0.001
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.001	0.999	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.001	0.999	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
A48 Other bacterial diseases, not elsewhere classified	0.000	0.999	0.001
C04 Malignant neoplasm of floor of mouth	0.001	0.999	0.000
I74 Arterial embolism and thrombosis	0.001	0.999	0.000
J90 Pleural effusion, not elsewhere classified	0.000	0.999	0.001
R31 Unspecified haematuria	0.000	0.999	0.001
C69.3 Choroid	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.000	0.999	0.001
H02.9 Disorder of eyelid, unspecified	0.001	0.999	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.001	0.999	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.000	0.999	0.001
M19.06 Primary arthrosis of other joints-Lower leg	0.001	0.999	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
A48.1 Legionnaires' disease	0.000	0.999	0.001
C71.3 Parietal lobe	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.000	0.999	0.001
H65.3 Chronic mucoid otitis media	0.001	0.999	0.000
H73.1 Chronic myringitis	0.001	0.999	0.000
H73.0 Acute myringitis	0.001	0.999	0.000
I87.1 Compression of vein	0.000	0.999	0.001
K35.0 Acute appendicitis with generalised peritonitis	0.001	0.999	0.000
O03.8 Complete or unspecified, with other and unspecified complications	0.000	0.999	0.001
O03.7 Complete or unspecified, complicated by embolism	0.000	0.999	0.001
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.999	0.001
O03.3 Incomplete, with other and unspecified complications	0.000	0.999	0.001
O03.2 Incomplete, complicated by embolism	0.000	0.999	0.001
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.999	0.001
O62.0 Primary inadequate contractions	0.001	0.999	0.000
O69.8 Labour and delivery complicated by other cord complications	0.001	0.999	0.000
A44 Bartonellosis	0.000	0.999	0.001
A43 Nocardiosis	0.000	0.999	0.001
A42 Actinomycosis	0.000	0.999	0.001
A39 Meningococcal infection	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations