TreeWAS – Variant ID: rs4077341

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K55.2 Angiodysplasia of colon	0.000	0.043	0.957
K55 Vascular disorders of intestine	0.000	0.591	0.409
K55.0 Acute vascular disorders of intestine	0.000	0.668	0.332
K55.8 Other vascular disorders of intestine	0.000	0.671	0.329
K55.9 Vascular disorder of intestine, unspecified	0.000	0.714	0.286
K55.1 Chronic vascular disorders of intestine	0.001	0.819	0.181
Y43.3 Other antineoplastic drugs	0.043	0.957	0.000
K60.1 Chronic anal fissure	0.000	0.957	0.043
Y43 Primarily systemic agents	0.039	0.961	0.000
Y43.1 Antineoplastic antimetabolites	0.036	0.964	0.000
Y43.2 Antineoplastic natural products	0.033	0.967	0.000
Y43.0 Antiallergic and antiemetic drugs	0.033	0.967	0.000
Y43.9 Primarily systemic agent, unspecified	0.028	0.972	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.028	0.972	0.000
Y43.6 Enzymes, not elsewhere classified	0.028	0.972	0.000
Y43.5 Acidifying and alkalising agents	0.028	0.972	0.000
Y43.4 Immunosuppressive agents	0.026	0.974	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.018	0.982	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.017	0.983	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.017	0.983	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.017	0.983	0.000
Y41.5 Antiviral drugs	0.016	0.984	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.016	0.984	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.015	0.985	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.985	0.015
Y42.5 Other oestrogens and progestogens	0.015	0.985	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.014	0.986	0.000
Y42.1 Thyroid hormones and substitutes	0.014	0.986	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.014	0.986	0.000
Y41.0 Sulphonamides	0.014	0.986	0.000
Y58 Bacterial vaccines	0.014	0.986	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.013	0.986	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.013	0.987	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.013	0.987	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.013	0.987	0.000
Y42.9 Other and unspecified hormone antagonists	0.013	0.987	0.000
Y42.2 Antithyroid drugs	0.013	0.987	0.000
Y59 Other and unspecified vaccines and biological substances	0.013	0.987	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.013	0.987	0.000
Y41.4 Anthelminthics	0.013	0.987	0.000
Y41.3 Other antiprotozoal drugs	0.013	0.987	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.013	0.987	0.000
Y41.1 Antimycobacterial drugs	0.013	0.987	0.000
Y42.4 Oral contraceptives	0.013	0.987	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.012	0.987	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.012	0.988	0.000
Y45.1 Salicylates	0.012	0.988	0.000
Y55.4 Expectorants	0.011	0.988	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.011	0.988	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.011	0.989	0.000
Y42.7 Androgens and anabolic congeners	0.011	0.989	0.000
Y49.2 Other and unspecified antidepressants	0.011	0.989	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.011	0.989	0.000
Y58.0 BCG vaccine	0.011	0.989	0.000
Y45.5 4-Aminophenol derivatives	0.011	0.989	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.011	0.989	0.000
Y40 Systemic antibiotics	0.011	0.989	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.011	0.989	0.000
Y45.2 Propionic acid derivatives	0.011	0.989	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.010	0.989	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.010	0.989	0.000
Y55.5 Anticommon cold drugs	0.010	0.989	0.000
Y55.3 Antitussives	0.010	0.989	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.010	0.989	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.010	0.989	0.000
Y55.0 Oxytocic drugs	0.010	0.989	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.010	0.990	0.000
Y50.9 Central nervous system stimulant, unspecified	0.010	0.990	0.000
Y50.8 Other central nervous system stimulants	0.010	0.990	0.000
Y50.1 Opioid receptor antagonists	0.010	0.990	0.000
Y50.0 Analeptics	0.010	0.990	0.000
Y58.9 Other and unspecified bacterial vaccines	0.010	0.990	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.010	0.990	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.010	0.990	0.000
Y58.5 Diphtheria vaccine	0.010	0.990	0.000
Y58.4 Tetanus vaccine	0.010	0.990	0.000
Y58.3 Plague vaccine	0.010	0.990	0.000
Y58.2 Cholera vaccine	0.010	0.990	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.010	0.990	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.010	0.990	0.000
Y59.0 Viral vaccines	0.010	0.990	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.010	0.990	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.010	0.990	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.010	0.990	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.010	0.990	0.000
Y51.0 Anticholinesterase agents	0.010	0.990	0.000
Y49.9 Psychotropic drug, unspecified	0.010	0.990	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
Y49.7 Psychostimulants with abuse potential	0.010	0.990	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.010	0.990	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.010	0.990	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.010	0.990	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.010	0.990	0.000
Y45.4 Antirheumatics	0.010	0.990	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.010	0.990	0.000
Y44 Agents primarily affecting blood constituents	0.010	0.990	0.000
Y59.9 Vaccine or biological substance, unspecified	0.009	0.991	0.000
Y59.8 Other specified vaccines and biological substances	0.009	0.991	0.000
Y59.2 Protozoal vaccines	0.009	0.991	0.000
Y59.1 Rickettsial vaccines	0.009	0.991	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.009	0.991	0.000
Y48 Anaesthetics and therapeutic gases	0.009	0.991	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.009	0.991	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.009	0.991	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.009	0.991	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.009	0.991	0.000
Y47.4 Bromine compounds	0.009	0.991	0.000
Y47.3 Paraldehyde	0.009	0.991	0.000
Y47.2 Chloral derivatives	0.009	0.991	0.000
Y47.0 Barbiturates, not elsewhere classified	0.009	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.009	0.991	0.000
O00.1 Tubal pregnancy	0.000	0.991	0.009
Y49.5 Other antipsychotics and neuroleptics	0.009	0.991	0.000
Y40.9 Systemic antibiotic, unspecified	0.009	0.991	0.000
Y47.1 Benzodiazepines	0.009	0.991	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.991	0.000
Y53.3 Saline and osmotic laxatives	0.009	0.991	0.000
Y59.3 Immunoglobulin	0.009	0.991	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.009	0.991	0.000
Y53.4 Other laxatives	0.009	0.991	0.000
Y56.9 Topical agent, unspecified	0.008	0.991	0.000
Y56.8 Other topical agents	0.008	0.991	0.000
Y56.7 Dental drugs, topically applied	0.008	0.991	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.008	0.991	0.000
Y56.5 Ophthalmological drugs and preparations	0.008	0.991	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.991	0.000
Y56.2 Local astringents and local detergents	0.008	0.991	0.000
Y56.1 Antipruritics	0.008	0.991	0.000
Y56.3 Emollients, demulcents and protectants	0.008	0.991	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.008	0.991	0.000
Y53.7 Emetics	0.008	0.991	0.000
Y53.6 Antidiarrhoeal drugs	0.008	0.991	0.000
Y53.5 Digestants	0.008	0.991	0.000
Y53.2 Stimulant laxatives	0.008	0.991	0.000
Y53.0 Histamine H2-receptor antagonists	0.008	0.991	0.000
Y57 Other and unspecified drugs and medicaments	0.008	0.991	0.000
Y44.5 Thrombolytic drugs	0.008	0.992	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.008	0.992	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.008	0.992	0.000
Y40.7 Antifungal antibiotics, systemically used	0.008	0.992	0.000
Y40.4 Tetracyclines	0.008	0.992	0.000
Y40.2 Chloramphenicol group	0.008	0.992	0.000
Y40.6 Rifamycins	0.008	0.992	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.007	0.992	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.007	0.993	0.000
Y44.7 Plasma substitutes	0.007	0.993	0.000
Y44.6 Natural blood and blood products	0.007	0.993	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.007	0.993	0.000
Y40.3 Macrolides	0.007	0.993	0.000
Y40.0 Penicillins	0.007	0.993	0.000
Y48.5 Therapeutic gases	0.007	0.993	0.000
Y48.1 Parenteral anaesthetics	0.007	0.993	0.000
Y48.0 Inhaled anaesthetics	0.007	0.993	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.007	0.993	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.007	0.993	0.000
Y48.4 Anaesthetic, unspecified	0.007	0.993	0.000
S92.00 Fracture of calcaneus (closed)	0.007	0.993	0.000
Y57.6 Other diagnostic agents	0.007	0.993	0.000
Y52 Agents primarily affecting the cardiovascular system	0.006	0.993	0.000
Y40.5 Aminoglycosides	0.006	0.993	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.006	0.994	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.994	0.006
Y57.7 Vitamins, not elsewhere classified	0.006	0.994	0.000
Y57.4 Pharmaceutical excipients	0.006	0.994	0.000
Y57.3 Alcohol deterrents	0.006	0.994	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.006	0.994	0.000
Y57.1 Lipotropic drugs	0.006	0.994	0.000
Y57.0 Appetite depressants [anorectics]	0.006	0.994	0.000
Y46.8 Antispasticity drugs	0.006	0.994	0.000
Y46.3 Deoxybarbiturates	0.006	0.994	0.000
Y46.1 Oxazolidinediones	0.006	0.994	0.000
Y46.0 Succinimides	0.006	0.994	0.000
Y57.5 X-ray contrast media	0.006	0.994	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.994	0.006
S96 Injury of muscle and tendon at ankle and foot level	0.006	0.994	0.000
Y46.5 Valproic acid	0.006	0.994	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.994	0.006
Y46.7 Anti-Parkinsonism drugs	0.006	0.994	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.006	0.994	0.000
S90-S99 Injuries to the ankle and foot	0.006	0.994	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
S92.0 Fracture of calcaneus	0.006	0.994	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.994	0.000
Y48.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
E87.2 Acidosis	0.000	0.994	0.006
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.000	0.994	0.006
Y46.6 Other and unspecified antiepileptics	0.006	0.994	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.006	0.994	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.006	0.994	0.000
Y48.3 Local anaesthetics	0.006	0.994	0.000
Y57.8 Other drugs and medicaments	0.006	0.994	0.000
S91 Open wound of ankle and foot	0.006	0.994	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
S92 Fracture of foot, except ankle	0.006	0.994	0.000
S93.0 Dislocation of ankle joint	0.006	0.994	0.000
H34.2 Other retinal artery occlusions	0.006	0.994	0.000
Y40.8 Other systemic antibiotics	0.005	0.994	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.005	0.994	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.994	0.006
S91.3 Open wound of other parts of foot	0.006	0.994	0.000
Y46.2 Hydantoin derivatives	0.005	0.995	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.005	0.995	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.995	0.005
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
E87.5 Hyperkalaemia	0.000	0.995	0.005
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.000	0.995	0.005
Y46.4 Iminostilbenes	0.005	0.995	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.005	0.995	0.000
S99 Other and unspecified injuries of ankle and foot	0.005	0.995	0.000
S97 Crushing injury of ankle and foot	0.005	0.995	0.000
S93.4 Sprain and strain of ankle	0.005	0.995	0.000
S93.5 Sprain and strain of toe(s)	0.005	0.995	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.000	0.995	0.005
S93.2 Rupture of ligaments at ankle and foot level	0.005	0.995	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.995	0.005
Y52.7 Peripheral vasodilators	0.005	0.995	0.000
S92.9 Fracture of foot, unspecified	0.005	0.995	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.005	0.995	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.005	0.995	0.000
Y52.1 Calcium-channel blockers	0.005	0.995	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.005	0.995	0.000
S91.1 Open wound of toe(s) without damage to nail	0.005	0.995	0.000
S98 Traumatic amputation of ankle and foot	0.005	0.995	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.995	0.005
S95 Injury of blood vessels at ankle and foot level	0.005	0.995	0.000
S94 Injury of nerves at ankle and foot level	0.005	0.995	0.000
O00 Ectopic pregnancy	0.000	0.995	0.005
F60.3 Emotionally unstable personality disorder	0.000	0.995	0.005
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.004	0.995	0.000
S92.01 Fracture of calcaneus (open)	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
S92.7 Multiple fractures of foot	0.004	0.996	0.000
Y54.9 Mineral salts, not elsewhere classified	0.004	0.996	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.996	0.000
Y54.0 Mineralocorticoids	0.004	0.996	0.000
S97.1 Crushing injury of toe(s)	0.004	0.996	0.000
K60 Fissure and fistula of anal and rectal regions	0.000	0.996	0.004
S91.7 Multiple open wounds of ankle and foot	0.004	0.996	0.000
S91.2 Open wound of toe(s) with damage to nail	0.004	0.996	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
S92.4 Fracture of great toe	0.004	0.996	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.000	0.996	0.004
Y54.3 Benzothiadiazine derivatives	0.004	0.996	0.000
S92.5 Fracture of other toe	0.004	0.996	0.000
S92.2 Fracture of other tarsal bone(s)	0.004	0.996	0.000
S92.1 Fracture of talus	0.004	0.996	0.000
Y54.7 Agents affecting calcification	0.004	0.996	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.004	0.996	0.000
S92.90 Fracture of foot, unspecified (closed)	0.004	0.996	0.000
E87.3 Alkalosis	0.000	0.996	0.004
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.996	0.004
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.996	0.004
S91.0 Open wound of ankle	0.004	0.996	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.000	0.996	0.004
O00.9 Ectopic pregnancy, unspecified	0.000	0.996	0.004
S02.60 Fracture of mandible (closed)	0.004	0.996	0.000
E87.7 Fluid overload	0.000	0.996	0.004
S92.41 Fracture of great toe (open)	0.004	0.996	0.000
S97.0 Crushing injury of ankle	0.004	0.996	0.000
S99.7 Multiple injuries of ankle and foot	0.004	0.996	0.000
Y54.8 Agents affecting uric acid metabolism	0.003	0.996	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.004	0.996	0.000
S93.40 Sprain of unspecified ligament of ankle	0.004	0.996	0.000
E87.4 Mixed disorder of acid-base balance	0.000	0.996	0.004
S92.91 Fracture of foot, unspecified (open)	0.003	0.996	0.000
Y45.0 Opioids and related analgesics	0.004	0.996	0.000
S98.1 Traumatic amputation of one toe	0.003	0.996	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.003	0.996	0.000
S94.8 Injury of other nerves at ankle and foot level	0.003	0.996	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.003	0.996	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.003	0.996	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.003	0.996	0.000
S94.1 Injury of medial plantar nerve	0.003	0.996	0.000
S94.0 Injury of lateral plantar nerve	0.003	0.996	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.003	0.996	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.003	0.996	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.003	0.996	0.000
S95.2 Injury of dorsal vein of foot	0.003	0.996	0.000
S95.1 Injury of plantar artery of foot	0.003	0.996	0.000
S95.0 Injury of dorsal artery of foot	0.003	0.996	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.003	0.996	0.000
S98.3 Traumatic amputation of other parts of foot	0.003	0.996	0.000
S98.2 Traumatic amputation of two or more toes	0.003	0.996	0.000
S98.0 Traumatic amputation of foot at ankle level	0.003	0.996	0.000
O00.8 Other ectopic pregnancy	0.000	0.996	0.003
O00.2 Ovarian pregnancy	0.000	0.996	0.003
O00.0 Abdominal pregnancy	0.000	0.996	0.003
Y54.4 Loop [high-ceiling] diuretics	0.003	0.996	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.000	0.996	0.004
S92.70 Multiple fractures of foot (closed)	0.003	0.996	0.000
K60.4 Rectal fistula	0.000	0.996	0.003
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
Y44.2 Anticoagulants	0.003	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.003	0.997	0.000
K60.0 Acute anal fissure	0.000	0.997	0.003
S92.3 Fracture of metatarsal bone	0.003	0.997	0.001
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.003	0.997	0.000
S92.11 Fracture of talus (open)	0.003	0.997	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.003	0.997	0.000
H34 Retinal vascular occlusions	0.003	0.997	0.000
F45.8 Other somatoform disorders	0.000	0.997	0.003
F60.9 Personality disorder, unspecified	0.000	0.997	0.003
F60 Specific personality disorders	0.000	0.997	0.003
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.997	0.003
S12.1 Fracture of second cervical vertebra	0.000	0.997	0.003
Y54.5 Other diuretics	0.003	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
S92.10 Fracture of talus (closed)	0.003	0.997	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.997	0.003
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.997	0.003
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.997	0.003
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
K12.1 Other forms of stomatitis	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.997	0.003
F60.6 Anxious [avoidant] personality disorder	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.997	0.003
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.000	0.997	0.003
M86.9 Osteomyelitis, unspecified	0.000	0.997	0.003
M06.9 Rheumatoid arthritis, unspecified	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.002	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.997	0.001
S12.2 Fracture of other specified cervical vertebra	0.000	0.997	0.003
K46 Unspecified abdominal hernia	0.000	0.997	0.003
K55-K64 Other diseases of intestines	0.000	0.997	0.003
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.003	0.997	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.997	0.003
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.997	0.003
S90 Superficial injury of ankle and foot	0.002	0.997	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.997	0.003
G51.0 Bell's palsy	0.003	0.997	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.997	0.003
H34.0 Transient retinal artery occlusion	0.002	0.997	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.997	0.003
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.997	0.002
F60.7 Dependent personality disorder	0.000	0.997	0.003
K60.5 Anorectal fistula	0.000	0.997	0.002
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.997	0.001
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.000	0.997	0.002
F60.2 Dissocial personality disorder	0.000	0.997	0.002
F60.1 Schizoid personality disorder	0.000	0.997	0.002
S12.11 Fracture of second cervical vertebra (open)	0.000	0.997	0.002
H34.1 Central retinal artery occlusion	0.002	0.997	0.000
L73.9 Follicular disorder, unspecified	0.002	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.998	0.002
M71.38 Other bursal cyst (Other)	0.002	0.998	0.000
S12 Fracture of neck	0.000	0.998	0.002
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.998	0.002
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
F60.5 Anankastic personality disorder	0.000	0.998	0.002
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.000	0.998	0.002
F60.8 Other specific personality disorders	0.000	0.998	0.002
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.998	0.002
R40.0 Somnolence	0.002	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.002
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
F60.0 Paranoid personality disorder	0.000	0.998	0.002
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.998	0.002
M86.93 Osteomyelitis, unspecified (Forearm)	0.000	0.998	0.002
M86.92 Osteomyelitis, unspecified (Upper arm)	0.000	0.998	0.002
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.000	0.998	0.002
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.000	0.998	0.002
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.998	0.002
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.998	0.002
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.998	0.002
F45.0 Somatisation disorder	0.000	0.998	0.002
F45.3 Somatoform autonomic dysfunction	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.998	0.002
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.000	0.998	0.002
R10.0 Acute abdomen	0.000	0.998	0.002
F45.9 Somatoform disorder, unspecified	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.001
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
O46.8 Other antepartum haemorrhage	0.000	0.998	0.002
S12.8 Fracture of other parts of neck	0.000	0.998	0.002
S12.0 Fracture of first cervical vertebra	0.000	0.998	0.002
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.000	0.998	0.002
F45.1 Undifferentiated somatoform disorder	0.000	0.998	0.002
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.998	0.002
S02.6 Fracture of mandible	0.002	0.998	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.998	0.002
K58 Irritable bowel syndrome	0.000	0.998	0.002
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
M06.98 Rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
Q51.3 Bicornate uterus	0.000	0.998	0.002
F45.2 Hypochondriacal disorder	0.000	0.998	0.002
K64.9 Haemorrhoids, unspecified	0.000	0.998	0.002
K64.8 Other specified haemorrhoids	0.000	0.998	0.002
K64.5 Perianal venous thrombosis	0.000	0.998	0.002
K64.4 Residual haemorrhoidal skin tags	0.000	0.998	0.002
K64.3 Fourth degree haemorrhoids	0.000	0.998	0.002
K64.2 Third degree haemorrhoids	0.000	0.998	0.002
K64.1 Second degree haemorrhoids	0.000	0.998	0.002
K64.0 First degree haemorrhoids	0.000	0.998	0.002
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.998	0.002
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
R07.0 Pain in throat	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
C84.5 Other and unspecified T-cell lymphomas	0.002	0.998	0.000
D76.3 Other histiocytosis syndromes	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.000	0.998	0.001
M86.98 Osteomyelitis, unspecified (Other)	0.000	0.998	0.001
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.002
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.002
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.002
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.002
S12.01 Fracture of first cervical vertebra (open)	0.000	0.998	0.001
S12.81 Fracture of other parts of neck (open)	0.000	0.998	0.001
S12.80 Fracture of other parts of neck (closed)	0.000	0.998	0.001
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.998	0.001
C18.9 Colon, unspecified	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
S02.61 Fracture of mandible (open)	0.002	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.001
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.001
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
K90.0 Coeliac disease	0.000	0.998	0.002
Z43.1 Attention to gastrostomy	0.000	0.998	0.002
Q51 Congenital malformations of uterus and cervix	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
D06.9 Cervix, unspecified	0.000	0.998	0.002
N34.3 Urethral syndrome, unspecified	0.000	0.998	0.002
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
G40.8 Other epilepsy	0.000	0.998	0.002
M71.3 Other bursal cyst	0.002	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
C84.4 Peripheral T-cell lymphoma	0.001	0.998	0.000
G83.2 Monoplegia of upper limb	0.002	0.998	0.000
U81.0 Vancomycin resistant agent	0.000	0.998	0.001
S12.91 Fracture of neck, part unspecified (open)	0.000	0.998	0.001
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.001
J01.9 Acute sinusitis, unspecified	0.001	0.998	0.000
O32.0 Maternal care for unstable lie	0.001	0.998	0.000
K61.1 Rectal abscess	0.000	0.999	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.999	0.001
O75.8 Other specified complications of labour and delivery	0.000	0.999	0.001
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M21.24 Flexion deformity (Hand)	0.000	0.999	0.001
K11.6 Mucocele of salivary gland	0.001	0.999	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.999	0.001
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.999	0.001
Q51.6 Embryonic cyst of cervix	0.000	0.999	0.001
Q51.5 Agenesis and aplasia of cervix	0.000	0.999	0.001
Q51.4 Unicornate uterus	0.000	0.999	0.001
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.999	0.001
Q51.0 Agenesis and aplasia of uterus	0.000	0.999	0.001
K11.2 Sialoadenitis	0.001	0.999	0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.001	0.999	0.000
M71.37 Other bursal cyst (Ankle and foot)	0.001	0.999	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.001	0.999	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.001	0.999	0.000
M71.39 Other bursal cyst (Site unspecified)	0.001	0.999	0.000
M71.36 Other bursal cyst (Lower leg)	0.001	0.999	0.000
M71.35 Other bursal cyst (Pelvic region and thigh)	0.001	0.999	0.000
M71.33 Other bursal cyst (Forearm)	0.001	0.999	0.000
M71.32 Other bursal cyst (Upper arm)	0.001	0.999	0.000
M71.31 Other bursal cyst (Shoulder region)	0.001	0.999	0.000
M71.30 Other bursal cyst (Multiple sites)	0.001	0.999	0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.000	0.999	0.001
F25.8 Other schizoaffective disorders	0.001	0.999	0.000
L50.9 Urticaria, unspecified	0.001	0.999	0.000
L65.9 Nonscarring hair loss, unspecified	0.000	0.999	0.001
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.999	0.001
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations