TreeWAS – Variant ID: rs41268932

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
J45 Asthma	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.996	0.004	0.000
I30-I52 Other forms of heart disease	0.996	0.004	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.995	0.005	0.000
J43 Emphysema	0.995	0.005	0.000
C15-C26 Malignant neoplasms of digestive organs	0.995	0.005	0.000
I50 Heart failure	0.995	0.005	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.994	0.006	0.000
E03 Other hypothyroidism	0.993	0.007	0.000
J43.9 Emphysema, unspecified	0.993	0.007	0.000
Chapter IX Diseases of the circulatory system	0.993	0.007	0.000
E00-E07 Disorders of thyroid gland	0.989	0.011	0.000
I42 Cardiomyopathy	0.987	0.013	0.000
I50.1 Left ventricular failure	0.985	0.015	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.985	0.015	0.000
C18 Malignant neoplasm of colon	0.982	0.018	0.000
I50.0 Congestive heart failure	0.981	0.019	0.000
J20-J22 Other acute lower respiratory infections	0.981	0.019	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.980	0.020	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.970	0.030	0.000
J22 Unspecified acute lower respiratory infection	0.964	0.036	0.000
D10-D36 Benign neoplasms	0.964	0.036	0.000
D00-D09 In situ neoplasms	0.963	0.037	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.962	0.038	0.000
M06.0 Seronegative rheumatoid arthritis	0.960	0.040	0.000
D12.8 Rectum	0.958	0.042	0.000
M20-M25 Other joint disorders	0.957	0.043	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.955	0.045	0.000
D12.5 Sigmoid colon	0.955	0.045	0.000
D50-D53 Nutritional anaemias	0.951	0.049	0.000
I51 Complications and ill-defined descriptions of heart disease	0.951	0.049	0.000
D27 Benign neoplasm of ovary	0.950	0.050	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.950	0.050	0.000
M06.3 Rheumatoid nodule	0.947	0.053	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.946	0.054	0.000
J30-J39 Other diseases of upper respiratory tract	0.944	0.056	0.000
D50 Iron deficiency anaemia	0.943	0.057	0.000
J33 Nasal polyp	0.943	0.057	0.000
M35 Other systemic involvement of connective tissue	0.941	0.059	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.939	0.061	0.000
J95-J99 Other diseases of the respiratory system	0.939	0.061	0.000
D60-D64 Aplastic and other anaemias	0.938	0.062	0.000
M35.3 Polymyalgia rheumatica	0.931	0.069	0.000
C21 Malignant neoplasm of anus and anal canal	0.931	0.069	0.000
C16 Malignant neoplasm of stomach	0.928	0.072	0.000
I47 Paroxysmal tachycardia	0.928	0.072	0.000
J33.0 Polyp of nasal cavity	0.927	0.073	0.000
D50.9 Iron deficiency anaemia, unspecified	0.926	0.074	0.000
C71 Malignant neoplasm of brain	0.920	0.080	0.000
J47 Bronchiectasis	0.920	0.080	0.000
E04 Other non-toxic goitre	0.907	0.093	0.000
C18.6 Descending colon	0.906	0.094	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.904	0.096	0.000
C18.3 Hepatic flexure	0.902	0.098	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.901	0.099	0.000
D64 Other anaemias	0.901	0.099	0.000
Chapter VIII Diseases of the ear and mastoid process	0.901	0.099	0.000
I42.0 Dilated cardiomyopathy	0.900	0.100	0.000
J33.9 Nasal polyp, unspecified	0.900	0.100	0.000
I31 Other diseases of pericardium	0.890	0.110	0.000
I51.7 Cardiomegaly	0.886	0.114	0.000
M06.4 Inflammatory polyarthropathy	0.879	0.121	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.877	0.123	0.000
D64.9 Anaemia, unspecified	0.875	0.125	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.869	0.131	0.000
D12.7 Rectosigmoid junction	0.865	0.135	0.000
I47.2 Ventricular tachycardia	0.863	0.137	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.862	0.138	0.000
I42.9 Cardiomyopathy, unspecified	0.861	0.139	0.000
N47 Redundant prepuce, phimosis and paraphimosis	0.860	0.140	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.859	0.141	0.000
D07.1 Vulva	0.853	0.147	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.846	0.154	0.000
C71.9 Brain, unspecified	0.845	0.155	0.000
D06 Carcinoma in situ of cervix uteri	0.844	0.156	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.843	0.157	0.000
M31 Other necrotising vasculopathies	0.843	0.157	0.000
M06.34 Rheumatoid nodule (Hand)	0.843	0.157	0.000
C21.1 Anal canal	0.841	0.159	0.000
I05-I09 Chronic rheumatic heart diseases	0.839	0.161	0.000
D62 Acute posthaemorrhagic anaemia	0.833	0.167	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.832	0.167	0.000
C18.0 Caecum	0.832	0.168	0.000
J98 Other respiratory disorders	0.832	0.168	0.000
J40 Bronchitis, not specified as acute or chronic	0.831	0.169	0.000
C71.0 Cerebrum, except lobes and ventricles	0.831	0.169	0.000
D50.8 Other iron deficiency anaemias	0.830	0.170	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.830	0.170	0.000
E04.9 Non-toxic goitre, unspecified	0.828	0.172	0.000
N40-N51 Diseases of male genital organs	0.824	0.176	0.000
D07.4 Penis	0.822	0.178	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.820	0.180	0.000
I42.2 Other hypertrophic cardiomyopathy	0.820	0.180	0.000
J46 Status asthmaticus	0.818	0.182	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.818	0.182	0.000
N48 Other disorders of penis	0.818	0.182	0.000
J84 Other interstitial pulmonary diseases	0.817	0.183	0.000
C07 Malignant neoplasm of parotid gland	0.817	0.183	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.816	0.184	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.813	0.187	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.811	0.189	0.000
I46 Cardiac arrest	0.810	0.190	0.000
N48.6 Balanitis xerotica obliterans	0.805	0.195	0.000
I31.3 Pericardial effusion (noninflammatory)	0.804	0.196	0.000
I42.6 Alcoholic cardiomyopathy	0.803	0.197	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.801	0.199	0.000
C21.0 Anus, unspecified	0.797	0.203	0.000
H80-H83 Diseases of inner ear	0.791	0.209	0.000
M34 Systemic sclerosis	0.791	0.209	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.788	0.211	0.000
J98.4 Other disorders of lung	0.788	0.212	0.000
M22 Disorders of patella	0.784	0.216	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.783	0.217	0.000
C18.9 Colon, unspecified	0.783	0.217	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.781	0.219	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.781	0.219	0.000
I08 Multiple valve diseases	0.780	0.220	0.000
J38.7 Other diseases of larynx	0.778	0.222	0.000
Chapter XIV Diseases of the genitourinary system	0.776	0.224	0.000
M31.6 Other giant cell arteritis	0.775	0.225	0.000
E06 Thyroiditis	0.770	0.230	0.000
D16 Benign neoplasm of bone and articular cartilage	0.767	0.233	0.000
J21 Acute bronchiolitis	0.765	0.235	0.000
I20-I25 Ischaemic heart diseases	0.761	0.239	0.000
J45.0 Predominantly allergic asthma	0.759	0.241	0.000
D06.9 Cervix, unspecified	0.759	0.241	0.000
C16.0 Cardia	0.757	0.243	0.000
C05 Malignant neoplasm of palate	0.753	0.247	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.752	0.248	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.752	0.248	0.000
M35.1 Other overlap syndromes	0.751	0.249	0.000
C18.2 Ascending colon	0.750	0.250	0.000
C17 Malignant neoplasm of small intestine	0.748	0.252	0.000
C18.5 Splenic flexure	0.748	0.252	0.000
I36 Nonrheumatic tricuspid valve disorders	0.747	0.253	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.746	0.254	0.000
J33.8 Other polyp of sinus	0.745	0.255	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.744	0.256	0.000
M40-M43 Deforming dorsopathies	0.743	0.257	0.000
E04.1 Non-toxic single thyroid nodule	0.741	0.259	0.000
C16.6 Greater curvature of stomach, unspecified	0.740	0.260	0.000
D34 Benign neoplasm of thyroid gland	0.739	0.261	0.000
I22 Subsequent myocardial infarction	0.738	0.262	0.000
M91-M94 Chondropathies	0.737	0.263	0.000
M11 Other crystal arthropathies	0.737	0.263	0.000
M30 Polyarteritis nodosa and related conditions	0.737	0.263	0.000
D52 Folate deficiency anaemia	0.736	0.264	0.000
C16.9 Stomach, unspecified	0.735	0.265	0.000
D22 Melanocytic naevi	0.733	0.267	0.000
J35 Chronic diseases of tonsils and adenoids	0.733	0.267	0.000
D29 Benign neoplasm of male genital organs	0.733	0.267	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.732	0.268	0.000
C16.3 Pyloric antrum	0.732	0.268	0.000
C09 Malignant neoplasm of tonsil	0.731	0.269	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.729	0.271	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.728	0.272	0.000
I46.0 Cardiac arrest with successful resuscitation	0.728	0.272	0.000
H81 Disorders of vestibular function	0.726	0.274	0.000
C16.2 Body of stomach	0.725	0.275	0.000
C15 Malignant neoplasm of oesophagus	0.724	0.276	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.723	0.277	0.000
C71.1 Frontal lobe	0.721	0.279	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.720	0.279	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.720	0.280	0.000
C22.0 Liver cell carcinoma	0.719	0.281	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.717	0.283	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.717	0.283	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
J45.8 Mixed asthma	0.717	0.283	0.000
J45.1 Nonallergic asthma	0.717	0.283	0.000
M05.8 Other seropositive rheumatoid arthritis	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.1 Rheumatoid lung disease	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
I42.8 Other cardiomyopathies	0.717	0.283	0.000
I52 Other heart disorders in diseases classified elsewhere	0.714	0.286	0.000
I48 Atrial fibrillation and flutter	0.714	0.286	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.714	0.286	0.000
I41 Myocarditis in diseases classified elsewhere	0.714	0.286	0.000
I40 Acute myocarditis	0.714	0.286	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.714	0.286	0.000
I37 Pulmonary valve disorders	0.714	0.286	0.000
I32 Pericarditis in diseases classified elsewhere	0.714	0.286	0.000
J43.8 Other emphysema	0.714	0.286	0.000
J43.1 Panlobular emphysema	0.714	0.286	0.000
J43.0 MacLeod's syndrome	0.714	0.286	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.713	0.286	0.000
C69 Malignant neoplasm of eye and adnexa	0.713	0.286	0.000
J38.0 Paralysis of vocal cords and larynx	0.712	0.288	0.000
E03.5 Myxoedema coma	0.712	0.288	0.000
E03.4 Atrophy of thyroid (acquired)	0.712	0.288	0.000
E03.3 Postinfectious hypothyroidism	0.712	0.288	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.712	0.288	0.000
E03.1 Congenital hypothyroidism without goitre	0.712	0.288	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.712	0.288	0.000
I00-I02 Acute rheumatic fever	0.712	0.288	0.000
C18.7 Sigmoid colon	0.711	0.289	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.711	0.289	0.000
I51.4 Myocarditis, unspecified	0.710	0.290	0.000
I47.1 Supraventricular tachycardia	0.710	0.290	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.709	0.291	0.000
E00 Congenital iodine-deficiency syndrome	0.709	0.291	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.709	0.291	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.707	0.292	0.000
I42.5 Other restrictive cardiomyopathy	0.707	0.292	0.000
I42.4 Endocardial fibroelastosis	0.707	0.292	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.707	0.292	0.000
I51.6 Cardiovascular disease, unspecified	0.706	0.294	0.000
C02.1 Border of tongue	0.706	0.294	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.705	0.295	0.000
D26 Other benign neoplasms of uterus	0.704	0.296	0.000
C18.8 Overlapping lesion of colon	0.704	0.296	0.000
C32 Malignant neoplasm of larynx	0.701	0.299	0.000
I08.0 Disorders of both mitral and aortic valves	0.701	0.299	0.000
M00-M03 Infectious arthropathies	0.701	0.299	0.000
H81.1 Benign paroxysmal vertigo	0.700	0.300	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.699	0.301	0.000
D55-D59 Haemolytic anaemias	0.698	0.302	0.000
J60-J70 Lung diseases due to external agents	0.697	0.303	0.000
E07 Other disorders of thyroid	0.697	0.303	0.000
J09-J18 Influenza and pneumonia	0.696	0.304	0.000
M60-M63 Disorders of muscles	0.696	0.304	0.000
N48.1 Balanoposthitis	0.692	0.307	0.000
J20 Acute bronchitis	0.692	0.308	0.000
D31 Benign neoplasm of eye and adnexa	0.691	0.309	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.691	0.309	0.000
D19 Benign neoplasm of mesothelial tissue	0.691	0.309	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.691	0.309	0.000
D09 Carcinoma in situ of other and unspecified sites	0.691	0.309	0.000
J37 Chronic laryngitis and laryngotracheitis	0.691	0.309	0.000
H90-H95 Other disorders of ear	0.691	0.309	0.000
D12.4 Descending colon	0.690	0.310	0.000
D12.1 Appendix	0.689	0.310	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.689	0.311	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.689	0.311	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.689	0.311	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.689	0.311	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.689	0.311	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.689	0.311	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.689	0.311	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.689	0.311	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.689	0.311	0.000
J42 Unspecified chronic bronchitis	0.688	0.312	0.000
C16.5 Lesser curvature of stomach, unspecified	0.688	0.312	0.000
D03 Melanoma in situ	0.687	0.313	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.686	0.313	0.000
M33 Dermatopolymyositis	0.686	0.313	0.000
M32 Systemic lupus erythematosus	0.686	0.313	0.000
C04 Malignant neoplasm of floor of mouth	0.686	0.314	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.685	0.315	0.000
C70 Malignant neoplasm of meninges	0.685	0.315	0.000
I51.8 Other ill-defined heart diseases	0.685	0.315	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.683	0.317	0.000
J99.0 Rheumatoid lung disease	0.683	0.317	0.000
D30 Benign neoplasm of urinary organs	0.682	0.318	0.000
D53 Other nutritional anaemias	0.682	0.318	0.000
I51.9 Heart disease, unspecified	0.682	0.318	0.000
I51.5 Myocardial degeneration	0.682	0.318	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.682	0.318	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.682	0.318	0.000
I51.0 Cardiac septal defect, acquired	0.682	0.318	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.679	0.321	0.000
M06.38 Rheumatoid nodule (Other)	0.679	0.321	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.679	0.321	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.679	0.321	0.000
M06.33 Rheumatoid nodule (Forearm)	0.679	0.321	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.679	0.321	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.679	0.321	0.000
C13 Malignant neoplasm of hypopharynx	0.678	0.322	0.000
C11 Malignant neoplasm of nasopharynx	0.678	0.322	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.678	0.322	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.678	0.322	0.000
C03 Malignant neoplasm of gum	0.678	0.322	0.000
C00 Malignant neoplasm of lip	0.678	0.322	0.000
C12 Malignant neoplasm of pyriform sinus	0.678	0.322	0.000
H60-H62 Diseases of external ear	0.676	0.324	0.000
D50.1 Sideropenic dysphagia	0.676	0.324	0.000
J33.1 Polypoid sinus degeneration	0.676	0.324	0.000
I47.0 Reentry ventricular arrhythmia	0.675	0.325	0.000
H65-H75 Diseases of middle ear and mastoid	0.675	0.325	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.674	0.325	0.000
M35.8 Other specified systemic involvement of connective tissue	0.674	0.325	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.674	0.325	0.000
M35.5 Multifocal fibrosclerosis	0.674	0.325	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.674	0.325	0.000
M35.2 Behcet's disease	0.674	0.325	0.000
C18.1 Appendix	0.674	0.326	0.000
D22.0 Melanocytic naevi of lip	0.674	0.326	0.000
J96 Respiratory failure, not elsewhere classified	0.673	0.327	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.672	0.328	0.000
M21 Other acquired deformities of limbs	0.672	0.328	0.000
I31.9 Disease of pericardium, unspecified	0.668	0.332	0.000
M14 Arthropathies in other diseases classified elsewhere	0.668	0.332	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.668	0.332	0.000
C21.2 Cloacogenic zone	0.668	0.332	0.000
J43.2 Centrilobular emphysema	0.666	0.333	0.000
C16.8 Overlapping lesion of stomach	0.666	0.334	0.000
C16.4 Pylorus	0.666	0.334	0.000
C16.1 Fundus of stomach	0.666	0.334	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.665	0.335	0.000
D01.3 Anus and anal canal	0.664	0.336	0.000
E40-E46 Malnutrition	0.663	0.337	0.000
C23 Malignant neoplasm of gallbladder	0.663	0.337	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.660	0.340	0.000
C71.8 Overlapping lesion of brain	0.660	0.340	0.000
C71.7 Brain stem	0.660	0.340	0.000
C71.6 Cerebellum	0.660	0.340	0.000
C71.5 Cerebral ventricle	0.660	0.340	0.000
C71.4 Occipital lobe	0.660	0.340	0.000
C71.2 Temporal lobe	0.659	0.340	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.659	0.340	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.655	0.345	0.000
I30 Acute pericarditis	0.654	0.346	0.000
C10 Malignant neoplasm of oropharynx	0.652	0.348	0.000
N48.0 Leukoplakia of penis	0.652	0.348	0.000
D00.0 Lip, oral cavity and pharynx	0.651	0.349	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.651	0.349	0.000
M34.1 CR(E)ST syndrome	0.651	0.349	0.000
E04.8 Other specified non-toxic goitre	0.650	0.350	0.000
D10 Benign neoplasm of mouth and pharynx	0.650	0.350	0.000
N48.5 Ulcer of penis	0.650	0.350	0.000
D07.6 Other and unspecified male genital organs	0.648	0.352	0.000
D07.3 Other and unspecified female genital organs	0.648	0.352	0.000
D07.2 Vagina	0.648	0.352	0.000
D07.0 Endometrium	0.648	0.352	0.000
E04.2 Non-toxic multinodular goitre	0.648	0.352	0.000
N45 Orchitis and epididymitis	0.648	0.352	0.000
D64.8 Other specified anaemias	0.646	0.354	0.000
D64.4 Congenital dyserythropoietic anaemia	0.646	0.354	0.000
D64.3 Other sideroblastic anaemias	0.646	0.354	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.646	0.354	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.646	0.354	0.000
D64.0 Hereditary sideroblastic anaemia	0.646	0.354	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.642	0.358	0.000
I09 Other rheumatic heart diseases	0.641	0.359	0.000
C32.0 Glottis	0.641	0.359	0.000
M10 Gout	0.639	0.361	0.000
I31.8 Other specified diseases of pericardium	0.638	0.362	0.000
I31.2 Haemopericardium, not elsewhere classified	0.638	0.362	0.000
I31.1 Chronic constrictive pericarditis	0.638	0.362	0.000
I31.0 Chronic adhesive pericarditis	0.638	0.362	0.000
C45 Mesothelioma	0.636	0.364	0.000
C02.9 Tongue, unspecified	0.636	0.364	0.000
K90 Intestinal malabsorption	0.001	0.365	0.635
M35.7 Hypermobility syndrome	0.634	0.366	0.000
J38.4 Oedema of larynx	0.634	0.366	0.000
J98.1 Pulmonary collapse	0.631	0.369	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.631	0.369	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.630	0.370	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.630	0.370	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.630	0.370	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.630	0.370	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.630	0.370	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.630	0.370	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.630	0.370	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.630	0.370	0.000
E50-E64 Other nutritional deficiencies	0.628	0.372	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.625	0.375	0.000
H90 Conductive and sensorineural hearing loss	0.623	0.377	0.000
J95.0 Tracheostomy malfunction	0.623	0.377	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.622	0.378	0.000
M22.4 Chondromalacia patellae	0.620	0.380	0.000
N48.9 Disorder of penis, unspecified	0.620	0.380	0.000
E03.8 Other specified hypothyroidism	0.620	0.380	0.000
D24 Benign neoplasm of breast	0.617	0.383	0.000
E04.0 Non-toxic diffuse goitre	0.615	0.385	0.000
M86-M90 Other osteopathies	0.615	0.385	0.000
I49 Other cardiac arrhythmias	0.614	0.386	0.000
C05.1 Soft palate	0.614	0.386	0.000
E06.3 Autoimmune thyroiditis	0.613	0.387	0.000
M22.8 Other disorders of patella	0.612	0.388	0.000
J98.9 Respiratory disorder, unspecified	0.612	0.388	0.000
D16.1 Short bones of upper limb	0.611	0.389	0.000
N48.8 Other specified disorders of penis	0.610	0.390	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.610	0.390	0.000
J21.9 Acute bronchiolitis, unspecified	0.610	0.390	0.000
C15.9 Oesophagus, unspecified	0.609	0.391	0.000
C22.9 Liver, unspecified	0.609	0.391	0.000
C17.9 Small intestine, unspecified	0.608	0.392	0.000
J38.6 Stenosis of larynx	0.607	0.393	0.000
I33 Acute and subacute endocarditis	0.607	0.393	0.000
C01 Malignant neoplasm of base of tongue	0.607	0.393	0.000
D04 Carcinoma in situ of skin	0.606	0.394	0.000
D23 Other benign neoplasms of skin	0.606	0.394	0.000
I22.8 Subsequent myocardial infarction of other sites	0.605	0.395	0.000
D06.7 Other parts of cervix	0.605	0.395	0.000
D06.1 Exocervix	0.605	0.395	0.000
D06.0 Endocervix	0.605	0.395	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.605	0.395	0.000
M31.9 Necrotising vasculopathy, unspecified	0.604	0.396	0.000
M31.8 Other specified necrotising vasculopathies	0.604	0.396	0.000
M31.7 Microscopic polyangiitis	0.604	0.396	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.604	0.396	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.604	0.396	0.000
M31.2 Lethal midline granuloma	0.604	0.396	0.000
M31.1 Thrombotic microangiopathy	0.604	0.396	0.000
M31.0 Hypersensitivity angiitis	0.604	0.396	0.000
I06 Rheumatic aortic valve diseases	0.602	0.398	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.599	0.401	0.000
J98.6 Disorders of diaphragm	0.596	0.404	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.596	0.404	0.000
J98.3 Compensatory emphysema	0.596	0.404	0.000
J98.2 Interstitial emphysema	0.596	0.404	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.596	0.404	0.000
M24 Other specific joint derangements	0.596	0.404	0.000
C71.3 Parietal lobe	0.594	0.406	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.591	0.408	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.591	0.409	0.000
N51 Disorders of male genital organs in diseases classified elsewhere	0.590	0.409	0.000
N46 Male infertility	0.590	0.409	0.000
N44 Torsion of testis	0.590	0.409	0.000
J38.2 Nodules of vocal cords	0.590	0.410	0.000
H80 Otosclerosis	0.589	0.411	0.000
M34.8 Other forms of systemic sclerosis	0.588	0.412	0.000
C02.8 Overlapping lesion of tongue	0.588	0.412	0.000
C02.4 Lingual tonsil	0.588	0.412	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.588	0.412	0.000
C02.2 Ventral surface of tongue	0.588	0.412	0.000
C02.0 Dorsal surface of tongue	0.588	0.412	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.587	0.413	0.000
N48.3 Priapism	0.586	0.414	0.000
J84.8 Other specified interstitial pulmonary diseases	0.586	0.414	0.000
J84.0 Alveolar and parietoalveolar conditions	0.586	0.414	0.000
H74 Other disorders of middle ear and mastoid	0.586	0.414	0.000
I08.8 Other multiple valve diseases	0.585	0.415	0.000
C22.7 Other specified carcinomas of liver	0.585	0.415	0.000
C22.4 Other sarcomas of liver	0.585	0.415	0.000
C22.3 Angiosarcoma of liver	0.585	0.415	0.000
C22.2 Hepatoblastoma	0.585	0.415	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.583	0.417	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.583	0.417	0.000
C31 Malignant neoplasm of accessory sinuses	0.583	0.417	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.583	0.417	0.000
C37 Malignant neoplasm of thymus	0.583	0.417	0.000
C33 Malignant neoplasm of trachea	0.583	0.417	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.583	0.417	0.000
D52.9 Folate deficiency anaemia, unspecified	0.582	0.418	0.000
M07 Psoriatic and enteropathic arthropathies	0.581	0.418	0.000
N42 Other disorders of prostate	0.582	0.418	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.581	0.419	0.000
I46.1 Sudden cardiac death, so described	0.580	0.419	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.580	0.420	0.000
D32 Benign neoplasm of meninges	0.580	0.420	0.000
M34.9 Systemic sclerosis, unspecified	0.579	0.420	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.579	0.421	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.577	0.422	0.000
C09.9 Tonsil, unspecified	0.578	0.422	0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.577	0.423	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.577	0.423	0.000
J38.3 Other diseases of vocal cords	0.576	0.424	0.000
J38.5 Laryngeal spasm	0.575	0.425	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.575	0.425	0.000
J81 Pulmonary oedema	0.575	0.425	0.000
M20 Acquired deformities of fingers and toes	0.574	0.426	0.000
C14.0 Pharynx, unspecified	0.573	0.426	0.000
J35.0 Chronic tonsillitis	0.571	0.429	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.568	0.432	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.567	0.433	0.000
D29.1 Prostate	0.567	0.433	0.000
C26.0 Intestinal tract, part unspecified	0.567	0.433	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.567	0.433	0.000
M34.0 Progressive systemic sclerosis	0.567	0.433	0.000
D01.9 Digestive organ, unspecified	0.565	0.435	0.000
D01.7 Other specified digestive organs	0.565	0.435	0.000
D01.5 Liver, gallbladder and bile ducts	0.565	0.435	0.000
D01.4 Other and unspecified parts of intestine	0.565	0.435	0.000
D01.2 Rectum	0.565	0.435	0.000
D01.1 Rectosigmoid junction	0.565	0.435	0.000
D01.0 Colon	0.565	0.435	0.000
M94 Other disorders of cartilage	0.564	0.435	0.000
M22.2 Patellofemoral disorders	0.563	0.436	0.000
M22.3 Other derangements of patella	0.563	0.437	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations