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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41272044
log Bayes Factor = 14.6049
Chromosome 6   position 161,014,751  (GRCh37) Explore rs41272044 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.001 0.999
I20.9 Angina pectoris, unspecified
0.000 0.001 0.999
I73 Other peripheral vascular diseases
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.001 0.999
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.002 0.998
I77 Other disorders of arteries and arterioles
0.000 0.003 0.997
I77.1 Stricture of artery
0.000 0.004 0.996
I25.2 Old myocardial infarction
0.000 0.011 0.989
Chapter IX Diseases of the circulatory system
0.000 0.029 0.971
I20.1 Angina pectoris with documented spasm
0.000 0.036 0.964
I22 Subsequent myocardial infarction
0.000 0.094 0.906
I70 Atherosclerosis
0.000 0.103 0.897
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.114 0.886
I74 Arterial embolism and thrombosis
0.000 0.132 0.868
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.134 0.866
I25.5 Ischaemic cardiomyopathy
0.000 0.135 0.865
I71 Aortic aneurysm and dissection
0.000 0.156 0.844
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.180 0.820
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.188 0.812
I77.8 Other specified disorders of arteries and arterioles
0.000 0.201 0.798
I20.0 Unstable angina
0.000 0.219 0.781
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.221 0.779
I27 Other pulmonary heart diseases
0.000 0.223 0.777
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.226 0.774
E78.0 Pure hypercholesterolaemia
0.000 0.228 0.772
E78.2 Mixed hyperlipidaemia
0.000 0.231 0.769
E78.5 Hyperlipidaemia, unspecified
0.000 0.231 0.769
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.235 0.765
I74.5 Embolism and thrombosis of iliac artery
0.000 0.241 0.759
I72 Other aneurysm
0.000 0.260 0.740
I73.8 Other specified peripheral vascular diseases
0.000 0.265 0.735
I27.2 Other secondary pulmonary hypertension
0.000 0.282 0.718
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.283 0.716
I77.5 Necrosis of artery
0.000 0.285 0.715
I77.4 Coeliac artery compression syndrome
0.000 0.285 0.715
I77.3 Arterial fibromuscular dysplasia
0.000 0.285 0.715
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.287 0.713
I25.3 Aneurysm of heart
0.000 0.289 0.711
I70.0 Atherosclerosis of aorta
0.000 0.293 0.707
I70.1 Atherosclerosis of renal artery
0.000 0.293 0.707
I72.4 Aneurysm of artery of lower extremity
0.000 0.294 0.706
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.307 0.693
I28 Other diseases of pulmonary vessels
0.000 0.311 0.689
I20.8 Other forms of angina pectoris
0.000 0.313 0.687
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.334 0.666
I23 Certain current complications following acute myocardial infarction
0.000 0.335 0.665
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.339 0.661
I77.2 Rupture of artery
0.000 0.341 0.659
I00-I02 Acute rheumatic fever
0.000 0.347 0.653
E78.1 Pure hyperglyceridaemia
0.000 0.349 0.651
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.352 0.648
I70.9 Generalised and unspecified atherosclerosis
0.000 0.357 0.643
I70.8 Atherosclerosis of other arteries
0.000 0.357 0.643
I27.9 Pulmonary heart disease, unspecified
0.000 0.359 0.641
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.372 0.628
I22.8 Subsequent myocardial infarction of other sites
0.000 0.375 0.625
I25.4 Coronary artery aneurysm
0.000 0.376 0.624
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.383 0.617
I77.0 Arteriovenous fistula, acquired
0.000 0.391 0.609
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.395 0.605
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.395 0.605
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.395 0.605
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.395 0.605
I26 Pulmonary embolism
0.000 0.420 0.580
I74.8 Embolism and thrombosis of other arteries
0.000 0.427 0.573
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.427 0.573
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.428 0.572
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.429 0.571
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.430 0.570
I28.8 Other specified diseases of pulmonary vessels
0.000 0.438 0.561
I27.0 Primary pulmonary hypertension
0.000 0.439 0.561
I27.1 Kyphoscoliotic heart disease
0.000 0.443 0.557
E78.3 Hyperchylomicronaemia
0.000 0.445 0.555
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.455 0.545
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.469 0.531
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.469 0.530
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.469 0.530
I72.1 Aneurysm of artery of upper extremity
0.000 0.469 0.530
I72.0 Aneurysm of carotid artery
0.000 0.482 0.518
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.490 0.509
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.493 0.507
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.493 0.507
E78.6 Lipoprotein deficiency
0.000 0.494 0.505
I72.3 Aneurysm of iliac artery
0.000 0.497 0.503
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.498 0.502
I72.2 Aneurysm of renal artery
0.000 0.500 0.500
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.506 0.494
I28.1 Aneurysm of pulmonary artery
0.000 0.506 0.494
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.506 0.494
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.517 0.483
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.521 0.479
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.523 0.477
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.523 0.477
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.523 0.477
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.523 0.477
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.523 0.477
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.523 0.477
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.523 0.477
I02 Rheumatic chorea
0.000 0.532 0.468
I01 Rheumatic fever with heart involvement
0.000 0.532 0.468
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.539 0.461
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.539 0.461
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.539 0.461
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.539 0.461
I10-I15 Hypertensive diseases
0.000 0.539 0.461
I11 Hypertensive heart disease
0.000 0.568 0.432
E78.8 Other disorders of lipoprotein metabolism
0.000 0.569 0.431
I23.8 Other current complications following acute myocardial infarction
0.000 0.574 0.425
I00 Rheumatic fever without mention of heart involvement
0.000 0.575 0.425
E78.4 Other hyperlipidaemia
0.000 0.575 0.424
I71.0 Dissection of aorta [any part]
0.000 0.591 0.409
I78 Diseases of capillaries
0.000 0.594 0.406
I72.9 Aneurysm of unspecified site
0.001 0.602 0.398
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.603 0.397
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.603 0.397
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.604 0.396
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.605 0.395
I27.8 Other specified pulmonary heart diseases
0.000 0.608 0.392
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.612 0.388
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.001 0.619 0.381
I79.1 Aortitis in diseases classified elsewhere
0.001 0.619 0.381
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.001 0.619 0.381
I77.6 Arteritis, unspecified
0.000 0.630 0.370
I24 Other acute ischaemic heart diseases
0.000 0.637 0.363
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.640 0.360
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.643 0.357
I99 Other and unspecified disorders of circulatory system
0.000 0.648 0.352
I05-I09 Chronic rheumatic heart diseases
0.000 0.660 0.340
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.664 0.336
I01.8 Other acute rheumatic heart disease
0.000 0.664 0.336
I01.2 Acute rheumatic myocarditis
0.000 0.664 0.336
I01.1 Acute rheumatic endocarditis
0.000 0.664 0.336
I01.0 Acute rheumatic pericarditis
0.000 0.664 0.336
I02.9 Rheumatic chorea without heart involvement
0.000 0.664 0.336
I02.0 Rheumatic chorea with heart involvement
0.000 0.664 0.336
I13 Hypertensive heart and renal disease
0.000 0.669 0.331
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.675 0.325
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.702 0.298
I78.9 Disease of capillaries, unspecified
0.000 0.709 0.291
I78.8 Other diseases of capillaries
0.000 0.710 0.290
I15 Secondary hypertension
0.000 0.716 0.283
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.717 0.283
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.717 0.283
I98.0 Cardiovascular syphilis
0.000 0.717 0.283
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.733 0.267
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.736 0.264
Z95.1 Presence of aortocoronary bypass graft
0.000 0.746 0.254
I73.0 Raynaud's syndrome
0.000 0.750 0.250
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.751 0.249
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.763 0.237
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.763 0.237
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.763 0.237
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.763 0.237
I07 Rheumatic tricuspid valve diseases
0.000 0.764 0.236
I05 Rheumatic mitral valve diseases
0.000 0.764 0.236
I09 Other rheumatic heart diseases
0.000 0.771 0.229
I06 Rheumatic aortic valve diseases
0.000 0.777 0.222
I72.8 Aneurysm of other specified arteries
0.002 0.779 0.219
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.782 0.217
I85 Oesophageal varices
0.000 0.788 0.212
I88 Nonspecific lymphadenitis
0.000 0.794 0.206
I15.9 Seconday hypertension, unspecified
0.000 0.796 0.204
I15.8 Other secondary hypertension
0.000 0.796 0.203
I15.2 Hypertension secondary to endocrine disorders
0.000 0.796 0.203
I15.0 Renovascular hypertension
0.000 0.796 0.203
I21 Acute myocardial infarction
0.000 0.799 0.201
I24.1 Dressler's syndrome
0.000 0.799 0.201
I86 Varicose veins of other sites
0.000 0.799 0.201
I05.2 Mitral stenosis with insufficiency
0.000 0.803 0.197
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.803 0.197
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.001 0.804 0.195
I24.8 Other forms of acute ischaemic heart disease
0.000 0.807 0.193
I86.4 Gastric varices
0.000 0.812 0.188
I87 Other disorders of veins
0.000 0.813 0.187
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.818 0.182
I85.9 Oesophageal varices without bleeding
0.000 0.820 0.180
I83 Varicose veins of lower extremities
0.000 0.823 0.177
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.826 0.174
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.828 0.172
I07.9 Tricuspid valve disease, unspecified
0.000 0.830 0.170
I07.8 Other tricuspid valve diseases
0.000 0.830 0.170
I07.2 Tricuspid stenosis with insufficiency
0.000 0.830 0.170
I07.0 Tricuspid stenosis
0.000 0.830 0.170
I05.8 Other mitral valve diseases
0.000 0.830 0.169
I87.1 Compression of vein
0.000 0.831 0.169
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.834 0.166
I09.8 Other specified rheumatic heart diseases
0.000 0.835 0.164
I09.2 Chronic rheumatic pericarditis
0.000 0.835 0.164
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.835 0.164
I09.0 Rheumatic myocarditis
0.000 0.835 0.164
I85.0 Oesophageal varices with bleeding
0.000 0.837 0.163
I95 Hypotension
0.000 0.837 0.162
I07.1 Tricuspid insufficiency
0.000 0.838 0.162
I05.9 Mitral valve disease, unspecified
0.000 0.839 0.161
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.840 0.160
I06.8 Other rheumatic aortic valve diseases
0.000 0.840 0.160
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.840 0.160
I06.1 Rheumatic aortic insufficiency
0.000 0.840 0.160
I05.0 Mitral stenosis
0.000 0.841 0.159
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.844 0.156
I97.0 Postcardiotomy syndrome
0.000 0.844 0.156
I15.1 Hypertension secondary to other renal disorders
0.000 0.844 0.156
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.846 0.154
I09.9 Rheumatic heart disease, unspecified
0.000 0.850 0.150
Z82.2 Family history of deafness and hearing loss
0.000 0.850 0.150
I88.8 Other nonspecific lymphadenitis
0.000 0.852 0.148
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.852 0.148
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.852 0.148
I97.1 Other functional disturbances following cardiac surgery
0.000 0.854 0.145
I82 Other venous embolism and thrombosis
0.000 0.855 0.145
I21.9 Acute myocardial infarction, unspecified
0.000 0.855 0.145
Z82.1 Family history of blindness and visual loss
0.000 0.855 0.145
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.856 0.144
I86.3 Vulval varices
0.000 0.856 0.144
I86.2 Pelvic varices
0.000 0.856 0.144
I86.0 Sublingual varices
0.000 0.856 0.144
I86.8 Varicose veins of other specified sites
0.000 0.857 0.143
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.859 0.141
I80 Phlebitis and thrombophlebitis
0.000 0.860 0.140
I05.1 Rheumatic mitral insufficiency
0.000 0.862 0.138
I06.0 Rheumatic aortic stenosis
0.000 0.862 0.138
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.862 0.138
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.862 0.138
I87.9 Disorder of vein, unspecified
0.000 0.865 0.134
I87.0 Postphlebitic syndrome
0.000 0.865 0.134
I81 Portal vein thrombosis
0.000 0.866 0.134
I95.0 Idiopathic hypotension
0.000 0.871 0.129
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.874 0.126
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.875 0.125
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.876 0.124
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.877 0.123
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.882 0.118
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.886 0.114
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.889 0.111
I12 Hypertensive renal disease
0.000 0.889 0.111
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.893 0.107
I82.1 Thrombophlebitis migrans
0.000 0.896 0.104
I82.0 Budd-Chiari syndrome
0.000 0.896 0.104
I82.3 Embolism and thrombosis of renal vein
0.000 0.897 0.103
I95.8 Other hypotension
0.000 0.898 0.102
I82.2 Embolism and thrombosis of vena cava
0.000 0.901 0.099
I95.2 Hypotension due to drugs
0.000 0.902 0.098
I82.8 Embolism and thrombosis of other specified veins
0.000 0.904 0.096
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.001 0.905 0.094
I95.1 Orthostatic hypotension
0.000 0.908 0.092
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.909 0.090
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.911 0.088
Z82.3 Family history of stroke
0.000 0.919 0.081
I87.8 Other specified disorders of veins
0.000 0.920 0.080
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.923 0.077
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.924 0.076
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.926 0.074
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.927 0.073
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.927 0.073
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.929 0.070
I08 Multiple valve diseases
0.000 0.932 0.068
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.936 0.064
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.937 0.062
I21.4 Acute subendocardial myocardial infarction
0.000 0.938 0.062
I78.1 Naevus, nonneoplastic
0.001 0.942 0.058
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.947 0.053
I86.1 Scrotal varices
0.001 0.949 0.051
I95.9 Hypotension, unspecified
0.000 0.949 0.051
I08.9 Multiple valve disease, unspecified
0.000 0.952 0.048
I08.8 Other multiple valve diseases
0.000 0.954 0.046
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.954 0.045
I08.0 Disorders of both mitral and aortic valves
0.000 0.959 0.041
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.960 0.040
Z95.3 Presence of xenogenic heart valve
0.000 0.961 0.039
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.962 0.038
I89.1 Lymphangitis
0.000 0.964 0.036
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.965 0.035
I12.9 Hypertensive renal disease without renal failure
0.001 0.971 0.028
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.974 0.026
I10 Essential (primary) hypertension
0.000 0.977 0.023
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.980 0.020
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.018 0.982 0.000
I60-I69 Cerebrovascular diseases
0.000 0.982 0.018
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.983 0.017
M21.3 Wrist or foot drop (acquired)
0.017 0.983 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.984 0.016
M21 Other acquired deformities of limbs
0.016 0.984 0.000
M21.2 Flexion deformity
0.015 0.985 0.000
I60 Subarachnoid haemorrhage
0.000 0.985 0.015
M21.7 Unequal limb length (acquired)
0.015 0.985 0.000
M21.27 Flexion deformity (Ankle and foot)
0.014 0.986 0.000
Z95.2 Presence of prosthetic heart valve
0.000 0.987 0.013
Z95.4 Presence of other heart-valve replacement
0.000 0.987 0.013
M21.76 Unequal limb length (acquired) (Lower leg)
0.013 0.987 0.000
M21.26 Flexion deformity (Lower leg)
0.013 0.987 0.000
M21.24 Flexion deformity (Hand)
0.013 0.987 0.000
I89.0 Lymphoedema, not elsewhere classified
0.000 0.987 0.013
M21.0 Valgus deformity, not elsewhere classified
0.013 0.987 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.987 0.012
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.988 0.012
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.988 0.012
M21.39 Wrist or foot drop (acquired)-Site unspec
0.012 0.988 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.012 0.988 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.012 0.988 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.012 0.988 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.012 0.988 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.012 0.988 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.012 0.988 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.012 0.988 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.012 0.988 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.012 0.988 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.988 0.012
M21.73 Unequal limb length (acquired) (Forearm)
0.012 0.988 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.988 0.012
I62 Other nontraumatic intracranial haemorrhage
0.000 0.988 0.012
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.012 0.988 0.000
M21.9 Acquired deformity of limb, unspecified
0.011 0.989 0.000
M21.8 Other specified acquired deformities of limbs
0.011 0.989 0.000
M21.29 Flexion deformity (Site unspecified)
0.011 0.989 0.000
M21.28 Flexion deformity (Other)
0.011 0.989 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.011 0.989 0.000
M21.23 Flexion deformity (Forearm)
0.011 0.989 0.000
M21.22 Flexion deformity (Upper arm)
0.011 0.989 0.000
M21.21 Flexion deformity (Shoulder region)
0.011 0.989 0.000
M21.20 Flexion deformity (Multiple sites)
0.011 0.989 0.000
M21.6 Other acquired deformities of ankle and foot
0.011 0.989 0.000
Z95.0 Presence of cardiac pacemaker
0.000 0.989 0.011
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.011 0.989 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.989 0.011
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.989 0.011
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.989 0.011
M21.79 Unequal limb length (acquired) (Site unspecified)
0.011 0.989 0.000
M21.78 Unequal limb length (acquired)-Other
0.011 0.989 0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)
0.011 0.989 0.000
M21.74 Unequal limb length (acquired) (Hand)
0.011 0.989 0.000
M21.72 Unequal limb length (acquired) (Upper arm)
0.011 0.989 0.000
M21.71 Unequal limb length (acquired)-Shldr region
0.011 0.989 0.000
M21.70 Unequal limb length (acquired) (Multiple sites)
0.011 0.989 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.989 0.011
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.989 0.010
I60.8 Other subarachnoid haemorrhage
0.000 0.990 0.010
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.990 0.010
M21.1 Varus deformity, not elsewhere classified
0.010 0.990 0.000
M21.4 Flat foot [pes planus] (acquired)
0.010 0.990 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.990 0.010
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.010 0.990 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.009 0.990 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.009 0.990 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.009 0.990 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.009 0.990 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.009 0.990 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.009 0.990 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.009 0.990 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.009 0.990 0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.991 0.009
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.991 0.009
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.991 0.009
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.991 0.009
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.009 0.991 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.991 0.009
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.991 0.009
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.991 0.009
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.991 0.009
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.991 0.009
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.009 0.991 0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.009 0.991 0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.009 0.991 0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.009 0.991 0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.009 0.991 0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.009 0.991 0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.009 0.991 0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.009 0.991 0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.009 0.991 0.000
Z90.1 Acquired absence of breast(s)
0.009 0.991 0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.991 0.009
I68.0 Cerebral amyloid angiopathy
0.000 0.991 0.009
I62.1 Nontraumatic extradural haemorrhage
0.000 0.991 0.008
M21.89 Other specified acquired deformities of limbs (Site unspecified)
0.008 0.991 0.000
M21.88 Other specified acquired deformities of limbs-Other
0.008 0.991 0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.008 0.991 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.008 0.991 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.008 0.991 0.000
M21.84 Other specified acquired deformities of limbs (Hand)
0.008 0.991 0.000
M21.83 Other specified acquired deformities of limbs (Forearm)
0.008 0.991 0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)
0.008 0.991 0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)
0.008 0.991 0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)
0.008 0.991 0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)
0.008 0.991 0.000
M21.98 Acquired deformity of limb, unspecified-Other
0.008 0.991 0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)
0.008 0.991 0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)
0.008 0.991 0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)
0.008 0.991 0.000
M21.94 Acquired deformity of limb, unspecified (Hand)
0.008 0.991 0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)
0.008 0.991 0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)
0.008 0.991 0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)
0.008 0.991 0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)
0.008 0.991 0.000
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.992 0.008
Z13.6 Special screening examination for cardiovascular disorders
0.000 0.992 0.008
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.008 0.992 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.008 0.992 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.008 0.992 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.008 0.992 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.008 0.992 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.008 0.992 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.008 0.992 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.008 0.992 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.008 0.992 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.008 0.992 0.000
R22.2 Localised swelling, mass and lump, trunk
0.000 0.992 0.008
I63 Cerebral infarction
0.000 0.992 0.008
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.007 0.992 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.007 0.992 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.007 0.992 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.007 0.992 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.007 0.992 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.007 0.992 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.007 0.992 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.007 0.992 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.007 0.992 0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.007 0.993 0.000
M21.48 Flat foot [pes planus] (acquired)-Other
0.007 0.993 0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.007 0.993 0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.007 0.993 0.000
M21.44 Flat foot [pes planus] (acquired)-Hand
0.007 0.993 0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.007 0.993 0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.007 0.993 0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.007 0.993 0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.007 0.993 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.993 0.007
I67 Other cerebrovascular diseases
0.000 0.993 0.007
G93.0 Cerebral cysts
0.000 0.993 0.007
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.993 0.007
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.993 0.007
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.993 0.007
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.993 0.006
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.006 0.994 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.994 0.006
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.994 0.006
I65.1 Occlusion and stenosis of basilar artery
0.000 0.994 0.006
M25.76 Osteophyte (Lower leg)
0.000 0.994 0.006
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.994 0.006
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.006 0.994 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.994 0.006
I67.9 Cerebrovascular disease, unspecified
0.000 0.994 0.006
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.994 0.006
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.994 0.006
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.994 0.006
G93 Other disorders of brain
0.000 0.994 0.006
G93.9 Disorder of brain, unspecified
0.000 0.994 0.006
E53.8 Deficiency of other specified B group vitamins
0.000 0.994 0.006
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.995 0.005
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.995 0.005
I67.5 Moyamoya disease
0.000 0.995 0.005
I67.4 Hypertensive encephalopathy
0.000 0.995 0.005
I67.3 Progressive vascular leukoencephalopathy
0.000 0.995 0.005
G93.6 Cerebral oedema
0.000 0.995 0.005
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.995 0.005
G95.2 Cord compression, unspecified
0.000 0.995 0.005
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.995 0.004
G93.2 Benign intracranial hypertension
0.000 0.995 0.005
I45.6 Preexcitation syndrome
0.000 0.995 0.005
G93.5 Compression of brain
0.000 0.995 0.005
G95.9 Disease of spinal cord, unspecified
0.000 0.995 0.005
H83.0 Labyrinthitis
0.000 0.995 0.005
G93.8 Other specified disorders of brain
0.000 0.995 0.005
I67.1 Cerebral aneurysm, nonruptured
0.000 0.995 0.005
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.000 0.995 0.005
R22.4 Localised swelling, mass and lump, lower limb
0.000 0.995 0.005
G95 Other diseases of spinal cord
0.000 0.995 0.005
R22.9 Localised swelling, mass and lump, unspecified
0.000 0.995 0.005
D21.1 Connective and other soft tissue of upper limb, including shoulder
0.004 0.995 0.000
G93.7 Reye's syndrome
0.000 0.996 0.004
M25.7 Osteophyte
0.000 0.996 0.004
I63.9 Cerebral infarction, unspecified
0.000 0.996 0.004
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.996 0.004
M25.71 Osteophyte (Shoulder region)
0.000 0.996 0.004
R22.1 Localised swelling, mass and lump, neck
0.000 0.996 0.004
I67.2 Cerebral atherosclerosis
0.000 0.996 0.004
M25.77 Osteophyte (Ankle and foot)
0.000 0.996 0.004
M25.72 Osteophyte (Upper arm)
0.000 0.996 0.004
G93.4 Encephalopathy, unspecified
0.000 0.996 0.004
M25.74 Osteophyte (Hand)
0.000 0.996 0.004
G95.1 Vascular myelopathies
0.000 0.996 0.004
I63.8 Other cerebral infarction
0.000 0.996 0.004
A49.8 Other bacterial infections of unspecified site
0.004 0.996 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.996 0.004
K35.0 Acute appendicitis with generalised peritonitis
0.004 0.996 0.000
K56.7 Ileus, unspecified
0.000 0.996 0.004
G90-G99 Other disorders of the nervous system
0.000 0.996 0.004
D21.2 Connective and other soft tissue of lower limb, including hip
0.003 0.996 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.000 0.996 0.003
M25.79 Osteophyte (Site unspecified)
0.000 0.997 0.003
M25.73 Osteophyte (Forearm)
0.000 0.997 0.003
M25.70 Osteophyte (Multiple sites)
0.000 0.997 0.003
M25.78 Osteophyte (Other)
0.000 0.997 0.003
M77.91 Enthesopathy, unspecified (Shoulder region)
0.000 0.997 0.003
G95.0 Syringomyelia and syringobulbia
0.000 0.997 0.003
G96.0 Cerebrospinal fluid leak
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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