TreeWAS – Variant ID: rs41273213

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
I25.8 Other forms of chronic ischaemic heart disease	0.996	0.004
Chapter V Mental and behavioural disorders	0.993	0.007
Chapter XIV Diseases of the genitourinary system	0.991	0.009
N70-N77 Inflammatory diseases of female pelvic organs	0.988	0.012
I70-I79 Diseases of arteries, arterioles and capillaries	0.987	0.013
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.986	0.014
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.985	0.015
S00-S09 Injuries to the head	0.985	0.015
Chapter XII Diseases of the skin and subcutaneous tissue	0.981	0.019
F10 Mental and behavioural disorders due to use of alcohol	0.981	0.019
Chapter IV Endocrine, nutritional and metabolic diseases	0.980	0.020
F10.1 Harmful use	0.977	0.023
I25.1 Atherosclerotic heart disease	0.973	0.027
L00-L08 Infections of the skin and subcutaneous tissue	0.962	0.038
Chapter VII Diseases of the eye and adnexa	0.962	0.038
N72 Inflammatory disease of cervix uteri	0.960	0.040
L03 Cellulitis	0.958	0.042
Chapter X Diseases of the respiratory system	0.955	0.045
I80 Phlebitis and thrombophlebitis	0.947	0.053
S00 Superficial injury of head	0.945	0.055
N30-N39 Other diseases of urinary system	0.943	0.057
F40-F48 Neurotic, stress-related and somatoform disorders	0.942	0.058
S80-S89 Injuries to the knee and lower leg	0.935	0.065
I24 Other acute ischaemic heart diseases	0.935	0.065
L03.1 Cellulitis of other parts of limb	0.932	0.068
H40-H42 Glaucoma	0.924	0.076
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.922	0.078
Chapter I Certain infectious and parasitic diseases	0.919	0.081
I60-I69 Cerebrovascular diseases	0.916	0.084
J09-J18 Influenza and pneumonia	0.915	0.085
Chapter VI Diseases of the nervous system	0.915	0.085
F41 Other anxiety disorders	0.914	0.086
I85 Oesophageal varices	0.909	0.091
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.908	0.092
L40-L45 Papulosquamous disorders	0.908	0.092
E70-E90 Metabolic disorders	0.903	0.097
Chapter XX External causes of morbidity and mortality	0.900	0.100
J80-J84 Other respiratory diseases principally affecting the interstitium	0.899	0.101
I71 Aortic aneurysm and dissection	0.898	0.102
N73 Other female pelvic inflammatory diseases	0.898	0.102
H40 Glaucoma	0.897	0.103
N75 Diseases of Bartholin's gland	0.893	0.107
E20-E35 Disorders of other endocrine glands	0.889	0.111
F41.9 Anxiety disorder, unspecified	0.888	0.112
I25.9 Chronic ischaemic heart disease, unspecified	0.886	0.114
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.884	0.116
I77 Other disorders of arteries and arterioles	0.882	0.118
S00.8 Superficial injury of other parts of head	0.880	0.120
L03.0 Cellulitis of finger and toe	0.873	0.127
E87 Other disorders of fluid, electrolyte and acid-base balance	0.872	0.128
S80 Superficial injury of lower leg	0.867	0.133
L40 Psoriasis	0.866	0.134
H55-H59 Other disorders of eye and adnexa	0.857	0.143
F10.0 Acute intoxication	0.854	0.146
W00-W19 Falls	0.853	0.147
N30 Cystitis	0.852	0.148
J18 Pneumonia, organism unspecified	0.851	0.149
S06 Intracranial injury	0.850	0.150
I22 Subsequent myocardial infarction	0.847	0.153
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.846	0.154
H40.9 Glaucoma, unspecified	0.845	0.155
S90-S99 Injuries to the ankle and foot	0.843	0.157
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.842	0.158
I24.8 Other forms of acute ischaemic heart disease	0.840	0.160
N76 Other inflammation of vagina and vulva	0.839	0.161
E87.1 Hypo-osmolality and hyponatraemia	0.839	0.161
N75.0 Cyst of Bartholin's gland	0.837	0.163
J20-J22 Other acute lower respiratory infections	0.837	0.163
I72 Other aneurysm	0.837	0.163
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.834	0.166
T79-T79 Certain early complications of trauma	0.832	0.168
J84 Other interstitial pulmonary diseases	0.830	0.169
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.829	0.171
I25.2 Old myocardial infarction	0.829	0.171
S20-S29 Injuries to the thorax	0.828	0.172
L40.9 Psoriasis, unspecified	0.827	0.173
H40.2 Primary angle-closure glaucoma	0.827	0.173
I85.9 Oesophageal varices without bleeding	0.826	0.174
I69 Sequelae of cerebrovascular disease	0.824	0.176
S00.1 Contusion of eyelid and periocular area	0.823	0.177
G90-G99 Other disorders of the nervous system	0.819	0.181
I20 Angina pectoris	0.814	0.186
N73.6 Female pelvic peritoneal adhesions	0.814	0.186
I70 Atherosclerosis	0.813	0.187
E10-E14 Diabetes mellitus	0.808	0.192
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.808	0.192
I25.5 Ischaemic cardiomyopathy	0.806	0.194
S01 Open wound of head	0.805	0.195
H10-H13 Disorders of conjunctiva	0.803	0.197
J18.1 Lobar pneumonia, unspecified	0.802	0.198
I67 Other cerebrovascular diseases	0.800	0.200
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.798	0.202
I25.4 Coronary artery aneurysm	0.798	0.202
L03.8 Cellulitis of other sites	0.797	0.203
E27 Other disorders of adrenal gland	0.796	0.204
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.794	0.206
S40-S49 Injuries to the shoulder and upper arm	0.793	0.207
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.793	0.207
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.792	0.208
L50-L54 Urticaria and erythema	0.791	0.209
N40-N51 Diseases of male genital organs	0.790	0.210
L03.2 Cellulitis of face	0.789	0.211
H57 Other disorders of eye and adnexa	0.788	0.212
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.788	0.212
I20.9 Angina pectoris, unspecified	0.784	0.216
W19 Unspecified fall	0.783	0.217
I25.3 Aneurysm of heart	0.780	0.220
S10-S19 Injuries to the neck	0.779	0.221
I24.9 Acute ischaemic heart disease, unspecified	0.775	0.225
E40-E46 Malnutrition	0.773	0.227
J84.9 Interstitial pulmonary disease, unspecified	0.770	0.230
S80.1 Contusion of other and unspecified parts of lower leg	0.770	0.230
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.768	0.232
F10.3 Withdrawal state	0.767	0.233
I81 Portal vein thrombosis	0.765	0.235
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.764	0.236
H04 Disorders of lachrymal system	0.763	0.237
I74 Arterial embolism and thrombosis	0.762	0.238
I82 Other venous embolism and thrombosis	0.762	0.238
J13 Pneumonia due to Streptococcus pneumoniae	0.762	0.238
I77.1 Stricture of artery	0.761	0.239
I87 Other disorders of veins	0.760	0.240
S00.2 Other superficial injuries of eyelid and periocular area	0.759	0.241
I71.3 Abdominal aortic aneurysm, ruptured	0.759	0.241
N31.8 Other neuromuscular dysfunction of bladder	0.757	0.243
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.757	0.243
S00.3 Superficial injury of nose	0.757	0.243
S05 Injury of eye and orbit	0.757	0.243
F12 Mental and behavioural disorders due to use of cannabinoids	0.756	0.244
N25-N29 Other disorders of kidney and ureter	0.756	0.244
S09 Other and unspecified injuries of head	0.755	0.245
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.754	0.246
R12 Heartburn	0.753	0.247
J22 Unspecified acute lower respiratory infection	0.753	0.247
J60-J70 Lung diseases due to external agents	0.752	0.248
S70-S79 Injuries to the hip and thigh	0.752	0.248
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.749	0.251
N10-N16 Renal tubulo-interstitial diseases	0.748	0.252
I05-I09 Chronic rheumatic heart diseases	0.747	0.253
B95-B98 Bacterial, viral and other infectious agents	0.746	0.254
E87.3 Alkalosis	0.746	0.254
I89.0 Lymphoedema, not elsewhere classified	0.746	0.254
T15-T19 Effects of foreign body entering through natural orifice	0.746	0.254
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.743	0.257
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.743	0.257
W19.9 Unspecified place	0.743	0.257
I64 Stroke, not specified as haemorrhage or infarction	0.741	0.259
I85.0 Oesophageal varices with bleeding	0.740	0.260
I78 Diseases of capillaries	0.740	0.260
L03.3 Cellulitis of trunk	0.740	0.260
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.737	0.263
I21 Acute myocardial infarction	0.736	0.264
S80.9 Superficial injury of lower leg, unspecified	0.735	0.265
E11 Non-insulin-dependent diabetes mellitus	0.735	0.265
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.734	0.266
F80-F89 Disorders of psychological development	0.730	0.270
G91 Hydrocephalus	0.729	0.271
F10.4 Withdrawal state with delirium	0.729	0.271
B15-B19 Viral hepatitis	0.728	0.272
B25-B34 Other viral diseases	0.727	0.273
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.725	0.275
A15-A19 Tuberculosis	0.724	0.276
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.723	0.277
I62 Other nontraumatic intracranial haemorrhage	0.722	0.278
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.721	0.279
S40 Superficial injury of shoulder and upper arm	0.720	0.279
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.719	0.280
S89 Other and unspecified injuries of lower leg	0.718	0.281
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.718	0.282
H57.9 Disorder of eye and adnexa, unspecified	0.717	0.282
E87.5 Hyperkalaemia	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.0 Atherosclerotic cardiovascular disease, so described	0.717	0.283
E78.5 Hyperlipidaemia, unspecified	0.717	0.283
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.717	0.283
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
N17-N19 Renal failure	0.715	0.285
N71 Inflammatory disease of uterus, except cervix	0.713	0.286
T79 Certain early complications of trauma, not elsewhere classified	0.713	0.287
S82 Fracture of lower leg, including ankle	0.713	0.287
G50-G59 Nerve, nerve root and plexus disorders	0.713	0.287
T66-T78 Other and unspecified effects of external causes	0.712	0.287
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.712	0.288
F70-F79 Mental retardation	0.712	0.288
F60-F69 Disorders of adult personality and behaviour	0.712	0.288
I67.1 Cerebral aneurysm, nonruptured	0.712	0.288
N30.8 Other cystitis	0.712	0.288
N47 Redundant prepuce, phimosis and paraphimosis	0.710	0.290
G93 Other disorders of brain	0.709	0.291
F41.2 Mixed anxiety and depressive disorder	0.709	0.291
J81 Pulmonary oedema	0.709	0.291
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.708	0.292
H52 Disorders of refraction and accommodation	0.708	0.292
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.707	0.293
I88 Nonspecific lymphadenitis	0.707	0.293
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.706	0.293
F18 Mental and behavioural disorders due to use of volatile solvents	0.706	0.293
F16 Mental and behavioural disorders due to use of hallucinogens	0.706	0.293
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.706	0.293
F14 Mental and behavioural disorders due to use of cocaine	0.706	0.293
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.706	0.293
F11 Mental and behavioural disorders due to use of opioids	0.706	0.293
S08 Traumatic amputation of part of head	0.706	0.294
S07 Crushing injury of head	0.706	0.294
S04 Injury of cranial nerves	0.706	0.294
S03 Dislocation, sprain and strain of joints and ligaments of head	0.706	0.294
I77.8 Other specified disorders of arteries and arterioles	0.705	0.295
E11.9 Without complications	0.705	0.295
X40-X49 Accidental poisoning by and exposure to noxious substances	0.704	0.296
L10-L14 Bullous disorders	0.704	0.296
F10.9 Unspecified mental and behavioural disorder	0.704	0.296
F10.8 Other mental and behavioural disorders	0.704	0.296
F10.7 Residual and late-onset psychotic disorder	0.704	0.296
F10.6 Amnesic syndrome	0.704	0.296
F10.5 Psychotic disorder	0.704	0.296
A00-A09 Intestinal infectious diseases	0.703	0.297
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.703	0.297
I77.9 Disorder of arteries and arterioles, unspecified	0.703	0.297
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.702	0.298
S50-S59 Injuries to the elbow and forearm	0.701	0.299
N73.9 Female pelvic inflammatory disease, unspecified	0.701	0.299
F00-F09 Organic, including symptomatic, mental disorders	0.700	0.300
G70-G73 Diseases of myoneural junction and muscle	0.700	0.300
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.699	0.301
J80 Adult respiratory distress syndrome	0.699	0.301
N30.9 Cystitis, unspecified	0.698	0.302
I72.3 Aneurysm of iliac artery	0.698	0.302
E23 Hypofunction and other disorders of pituitary gland	0.696	0.304
H40.0 Glaucoma suspect	0.696	0.304
J11 Influenza, virus not identified	0.695	0.305
T98 Sequelae of other and unspecified effects of external causes	0.695	0.305
X10-X19 Contact with heat and hot substances	0.694	0.305
N39 Other disorders of urinary system	0.694	0.306
S01.3 Open wound of ear	0.694	0.306
I71.0 Dissection of aorta [any part]	0.694	0.306
S06.6 Traumatic subarachnoid haemorrhage	0.694	0.306
N76.8 Other specified inflammation of vagina and vulva	0.692	0.308
H04.2 Epiphora	0.692	0.308
F43 Reaction to severe stress, and adjustment disorders	0.691	0.309
I60 Subarachnoid haemorrhage	0.691	0.309
L05 Pilonidal cyst	0.690	0.309
E73 Lactose intolerance	0.690	0.309
L04 Acute lymphadenitis	0.690	0.310
L01 Impetigo	0.690	0.310
L00 Staphylococcal scalded skin syndrome	0.690	0.310
H46-H48 Disorders of optic nerve and visual pathways	0.690	0.310
E87.7 Fluid overload	0.690	0.310
E50-E64 Other nutritional deficiencies	0.690	0.310
N10 Acute tubulo-interstitial nephritis	0.689	0.311
S00.7 Multiple superficial injuries of head	0.688	0.312
J10 Influenza due to identified influenza virus	0.688	0.312
S92 Fracture of foot, except ankle	0.687	0.313
I22.9 Subsequent myocardial infarction of unspecified site	0.686	0.314
L80-L99 Other disorders of the skin and subcutaneous tissue	0.686	0.314
N34 Urethritis and urethral syndrome	0.684	0.316
B35-B49 Mycoses	0.683	0.317
G62 Other polyneuropathies	0.682	0.318
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.680	0.320
X50-X57 Overexertion, travel and privation	0.680	0.320
S27 Injury of other and unspecified intrathoracic organs	0.680	0.320
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.680	0.320
B20-B24 Human immunodeficiency virus [HIV] disease	0.679	0.321
G56 Mononeuropathies of upper limb	0.679	0.321
S90 Superficial injury of ankle and foot	0.678	0.322
S00.5 Superficial injury of lip and oral cavity	0.678	0.322
S00.4 Superficial injury of ear	0.678	0.322
V40-V49 Car occupant injured in transport accident	0.678	0.322
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.676	0.323
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.676	0.324
N37 Urethral disorders in diseases classified elsewhere	0.676	0.324
N33 Bladder disorders in diseases classified elsewhere	0.676	0.324
J95-J99 Other diseases of the respiratory system	0.676	0.324
Chapter XXII Codes for special purposes	0.675	0.324
F48 Other neurotic disorders	0.675	0.325
F44 Dissociative [conversion] disorders	0.675	0.325
F42 Obsessive-compulsive disorder	0.675	0.325
T90 Sequelae of injuries of head	0.675	0.325
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.674	0.325
N17 Acute renal failure	0.674	0.326
L40.5 Arthropathic psoriasis	0.673	0.327
E78.2 Mixed hyperlipidaemia	0.673	0.327
X20-X29 Contact with venomous animals and plants	0.672	0.328
R17 Unspecified jaundice	0.671	0.329
H11 Other disorders of conjunctiva	0.671	0.329
S06.2 Diffuse brain injury	0.671	0.329
S88 Traumatic amputation of lower leg	0.671	0.329
S87 Crushing injury of lower leg	0.671	0.329
S86 Injury of muscle and tendon at lower leg level	0.671	0.329
S85 Injury of blood vessels at lower leg level	0.671	0.329
S84 Injury of nerves at lower leg level	0.671	0.329
E27.1 Primary adrenocortical insufficiency	0.670	0.330
I24.1 Dressler's syndrome	0.670	0.330
I22.8 Subsequent myocardial infarction of other sites	0.668	0.331
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.668	0.332
E16 Other disorders of pancreatic internal secretion	0.668	0.332
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.668	0.332
H04.5 Stenosis and insufficiency of lachrymal passages	0.668	0.332
F41.1 Generalised anxiety disorder	0.667	0.333
W06 Fall involving bed	0.667	0.333
B90-B94 Sequelae of infectious and parasitic diseases	0.666	0.334
A50-A64 Infections with a predominantly sexual mode of transmission	0.666	0.334
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.665	0.334
E78.9 Disorder of lipoprotein metabolism, unspecified	0.665	0.335
N50 Other disorders of male genital organs	0.665	0.335
H50 Other strabismus	0.664	0.336
E28 Ovarian dysfunction	0.663	0.336
L53 Other erythematous conditions	0.663	0.337
N30.3 Trigonitis	0.663	0.337
H42 Glaucoma in diseases classified elsewhere	0.662	0.337
N76.0 Acute vaginitis	0.662	0.338
Q38-Q45 Other congenital malformations of the digestive system	0.662	0.338
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.661	0.339
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.661	0.339
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.661	0.339
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.660	0.340
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.660	0.340
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.660	0.340
B99-B99 Other infectious diseases	0.659	0.341
B85-B89 Pediculosis, acariasis and other infestations	0.659	0.341
B65-B83 Helminthiases	0.659	0.341
B50-B64 Protozoal diseases	0.659	0.341
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.659	0.341
A80-A89 Viral infections of the central nervous system	0.659	0.341
A75-A79 Rickettsioses	0.659	0.341
A70-A74 Other diseases caused by chlamydiae	0.659	0.341
A65-A69 Other spirochaetal diseases	0.659	0.341
A20-A28 Certain zoonotic bacterial diseases	0.659	0.341
V20-V29 Motorcycle rider injured in transport accident	0.658	0.342
S22 Fracture of rib(s), sternum and thoracic spine	0.658	0.342
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.657	0.343
I68 Cerebrovascular disorders in diseases classified elsewhere	0.657	0.343
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.657	0.343
J17 Pneumonia in diseases classified elsewhere	0.656	0.344
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.656	0.344
J15 Bacterial pneumonia, not elsewhere classified	0.656	0.344
J12 Viral pneumonia, not elsewhere classified	0.656	0.344
J14 Pneumonia due to Haemophilus influenzae	0.656	0.344
J09 Influenza due to certain identified influenza virus	0.656	0.344
F41.8 Other specified anxiety disorders	0.656	0.344
F41.3 Other mixed anxiety disorders	0.656	0.344
W20-W49 Exposure to inanimate mechanical forces	0.655	0.344
F40 Phobic anxiety disorders	0.655	0.345
G56.0 Carpal tunnel syndrome	0.655	0.345
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.652	0.348
L44 Other papulosquamous disorders	0.651	0.349
L41 Parapsoriasis	0.651	0.349
L45 Papulosquamous disorders in diseases classified elsewhere	0.651	0.349
L42 Pityriasis rosea	0.651	0.349
H43-H45 Disorders of vitreous body and globe	0.650	0.350
G30-G32 Other degenerative diseases of the nervous system	0.649	0.350
S02 Fracture of skull and facial bones	0.649	0.351
S00.0 Superficial injury of scalp	0.649	0.351
G91.9 Hydrocephalus, unspecified	0.648	0.352
I70.2 Atherosclerosis of arteries of the extremities	0.648	0.352
E85 Amyloidosis	0.647	0.353
E84 Cystic fibrosis	0.647	0.353
E79 Disorders of purine and pyrimidine metabolism	0.647	0.353
E77 Disorders of glycoprotein metabolism	0.647	0.353
E76 Disorders of glycosaminoglycan metabolism	0.647	0.353
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.647	0.353
E74 Other disorders of carbohydrate metabolism	0.647	0.353
E72 Other disorders of amino-acid metabolism	0.647	0.353
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.647	0.353
E70 Disorders of aromatic amino-acid metabolism	0.647	0.353
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.647	0.353
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.647	0.353
I73 Other peripheral vascular diseases	0.647	0.353
X60-X84 Intentional self-harm	0.646	0.353
G00-G09 Inflammatory diseases of the central nervous system	0.645	0.355
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.645	0.355
Y35-Y36 Legal intervention and operations of war	0.645	0.355
Y10-Y34 Event of undetermined intent	0.645	0.355
Y00-Y09 Assault	0.645	0.355
X85-X99 Assault	0.645	0.355
X58-X59 Accidental exposure to other and unspecified factors	0.645	0.355
X30-X39 Exposure to forces of nature	0.645	0.355
X00-X09 Exposure to smoke, fire and flames	0.645	0.355
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.645	0.355
W75-W84 Other accidental threats to breathing	0.645	0.355
W65-W74 Accidental drowning and submersion	0.645	0.355
W50-W64 Exposure to animate mechanical forces	0.645	0.355
V98-V99 Other and unspecified transport accidents	0.645	0.355
V95-V97 Air and space transport accidents	0.645	0.355
V90-V94 Water transport accidents	0.645	0.355
V70-V79 Bus occupant injured in transport accident	0.645	0.355
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.645	0.355
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.645	0.355
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.645	0.355
V01-V09 Pedestrian injured in transport accident	0.645	0.355
N17.9 Acute renal failure, unspecified	0.645	0.355
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.644	0.355
J82 Pulmonary eosinophilia, not elsewhere classified	0.644	0.355
I71.8 Aortic aneurysm of unspecified site, ruptured	0.644	0.356
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.644	0.356
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.644	0.356
I71.1 Thoracic aortic aneurysm, ruptured	0.644	0.356
I69.1 Sequelae of intracerebral haemorrhage	0.644	0.356
N73.8 Other specified female pelvic inflammatory diseases	0.644	0.356
N73.5 Female pelvic peritonitis, unspecified	0.644	0.356
N73.4 Female chronic pelvic peritonitis	0.644	0.356
N73.3 Female acute pelvic peritonitis	0.644	0.356
N73.2 Unspecified parametritis and pelvic cellulitis	0.644	0.356
N73.1 Chronic parametritis and pelvic cellulitis	0.644	0.356
N73.0 Acute parametritis and pelvic cellulitis	0.644	0.356
J18.0 Bronchopneumonia, unspecified	0.644	0.356
G35-G37 Demyelinating diseases of the central nervous system	0.643	0.357
R26 Abnormalities of gait and mobility	0.643	0.357
H40.8 Other glaucoma	0.643	0.357
H40.6 Glaucoma secondary to drugs	0.643	0.357
H40.4 Glaucoma secondary to eye inflammation	0.643	0.357
H40.3 Glaucoma secondary to eye trauma	0.643	0.357
E27.2 Addisonian crisis	0.642	0.357
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.642	0.358
I72.8 Aneurysm of other specified arteries	0.641	0.359
N75.9 Disease of Bartholin's gland, unspecified	0.641	0.359
N75.8 Other diseases of Bartholin's gland	0.641	0.359
J84.1 Other interstitial pulmonary diseases with fibrosis	0.641	0.359
E78.4 Other hyperlipidaemia	0.640	0.360
I70.0 Atherosclerosis of aorta	0.640	0.360
F99-F99 Unspecified mental disorder	0.638	0.362
E35 Disorders of endocrine glands in diseases classified elsewhere	0.638	0.362
E34 Other endocrine disorders	0.638	0.362
E32 Diseases of thymus	0.638	0.362
E31 Polyglandular dysfunction	0.638	0.362
E30 Disorders of puberty, not elsewhere classified	0.638	0.362
E29 Testicular dysfunction	0.638	0.362
E26 Hyperaldosteronism	0.638	0.362
E25 Adrenogenital disorders	0.638	0.362
E24 Cushing's syndrome	0.638	0.362
E20 Hypoparathyroidism	0.638	0.362
S06.5 Traumatic subdural haemorrhage	0.638	0.362
N46 Male infertility	0.638	0.362
H40.5 Glaucoma secondary to other eye disorders	0.637	0.362
W07 Fall involving chair	0.637	0.363
I86 Varicose veins of other sites	0.636	0.364
H49 Paralytic strabismus	0.635	0.365
R11 Nausea and vomiting	0.635	0.365
H57.1 Ocular pain	0.635	0.365
S80.8 Other superficial injuries of lower leg	0.634	0.366
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.634	0.366
G80-G83 Cerebral palsy and other paralytic syndromes	0.634	0.366
I84 Haemorrhoids	0.634	0.366
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.634	0.366
I21.0 Acute transmural myocardial infarction of anterior wall	0.633	0.367
I77.5 Necrosis of artery	0.633	0.367
I77.4 Coeliac artery compression syndrome	0.633	0.367
I77.3 Arterial fibromuscular dysplasia	0.633	0.367
I77.2 Rupture of artery	0.633	0.367
I77.0 Arteriovenous fistula, acquired	0.633	0.367
V80-V89 Other land transport accidents	0.631	0.369
N30.1 Interstitial cystitis (chronic)	0.631	0.369
H04.3 Acute and unspecified inflammation of lachrymal passages	0.631	0.369
H04.4 Chronic inflammation of lachrymal passages	0.629	0.371
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.629	0.371
R19 Other symptoms and signs involving the digestive system and abdomen	0.629	0.371
S01.9 Open wound of head, part unspecified	0.628	0.372
H03 Disorders of eyelid in diseases classified elsewhere	0.628	0.372
I22.0 Subsequent myocardial infarction of anterior wall	0.627	0.372
I21.1 Acute transmural myocardial infarction of inferior wall	0.627	0.373
I69.0 Sequelae of subarachnoid haemorrhage	0.627	0.373
S06.0 Concussion	0.627	0.373
T86 Failure and rejection of transplanted organs and tissues	0.626	0.374
N60-N64 Disorders of breast	0.626	0.374
E46 Unspecified protein-energy malnutrition	0.626	0.374
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.625	0.374
E87.4 Mixed disorder of acid-base balance	0.625	0.374
N39.8 Other specified disorders of urinary system	0.625	0.375
T91 Sequelae of injuries of neck and trunk	0.625	0.375
Y60-Y69 Misadventures to patients during surgical and medical care	0.624	0.376
R25 Abnormal involuntary movements	0.624	0.376
Q80-Q89 Other congenital malformations	0.623	0.377
E00-E07 Disorders of thyroid gland	0.623	0.377
S80.7 Multiple superficial injuries of lower leg	0.621	0.378
S80.0 Contusion of knee	0.621	0.378
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.621	0.379
E27.9 Disorder of adrenal gland, unspecified	0.621	0.379
L40.8 Other psoriasis	0.621	0.379
L40.4 Guttate psoriasis	0.621	0.379
L40.3 Pustulosis palmaris et plantaris	0.621	0.379
L40.2 Acrodermatitis continua	0.621	0.379
L40.1 Generalised pustular psoriasis	0.621	0.379
L40.0 Psoriasis vulgaris	0.621	0.379
N30.0 Acute cystitis	0.620	0.380
W02.9 Unspecified place	0.620	0.380
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.619	0.381
H52.0 Hypermetropia	0.619	0.381
A04 Other bacterial intestinal infections	0.619	0.381
S82.1 Fracture of upper end of tibia	0.618	0.382
S10 Superficial injury of neck	0.617	0.382

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations