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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs41279092
log Bayes Factor = 7.635
Chromosome 12   position 112,924,706  (GRCh37) Explore rs41279092 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.001 0.999
I25 Chronic ischaemic heart disease
0.000 0.001 0.999
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.000 0.001 0.999
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.000 0.001 0.999
I20 Angina pectoris
0.000 0.003 0.997
I25.1 Atherosclerotic heart disease
0.000 0.007 0.993
Z88.6 Personal history of allergy to analgesic agent
0.000 0.010 0.990
I20.0 Unstable angina
0.000 0.016 0.984
Chapter IX Diseases of the circulatory system
0.000 0.018 0.982
E70-E90 Metabolic disorders
0.000 0.018 0.982
I30-I52 Other forms of heart disease
0.000 0.018 0.982
I21.9 Acute myocardial infarction, unspecified
0.000 0.021 0.979
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.022 0.978
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.023 0.977
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.026 0.974
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.029 0.971
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.030 0.970
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.033 0.967
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.036 0.964
E83 Disorders of mineral metabolism
0.000 0.037 0.963
E78.5 Hyperlipidaemia, unspecified
0.000 0.037 0.963
I20.9 Angina pectoris, unspecified
0.000 0.038 0.962
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.000 0.039 0.961
E00-E07 Disorders of thyroid gland
0.000 0.047 0.953
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.047 0.953
E83.5 Disorders of calcium metabolism
0.000 0.050 0.950
# Top node
0.000 0.051 0.949
Chapter XXI Factors influencing health status and contact with health services
0.000 0.052 0.948
Chapter X Diseases of the respiratory system
0.000 0.056 0.944
I49 Other cardiac arrhythmias
0.000 0.068 0.932
I44 Atrioventricular and left bundle-branch block
0.000 0.068 0.932
Chapter V Mental and behavioural disorders
0.000 0.069 0.931
Z95.4 Presence of other heart-valve replacement
0.000 0.069 0.931
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.073 0.927
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.076 0.924
E03 Other hypothyroidism
0.000 0.077 0.923
Z70-Z76 Persons encountering health services in other circumstances
0.000 0.078 0.922
Z72 Problems related to lifestyle
0.000 0.083 0.917
Z88.3 Personal history of allergy to other anti-infective agents
0.000 0.087 0.913
Z72.0 Tobacco use
0.000 0.091 0.909
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.092 0.908
E03.9 Hypothyroidism, unspecified
0.000 0.093 0.907
I51 Complications and ill-defined descriptions of heart disease
0.000 0.093 0.907
J30-J39 Other diseases of upper respiratory tract
0.000 0.097 0.903
J34 Other disorders of nose and nasal sinuses
0.000 0.101 0.899
I45 Other conduction disorders
0.000 0.107 0.893
E87.5 Hyperkalaemia
0.000 0.108 0.892
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.110 0.890
Z83 Family history of other specific disorders
0.000 0.110 0.890
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.113 0.887
E87.2 Acidosis
0.000 0.115 0.885
I44.7 Left bundle-branch block, unspecified
0.000 0.122 0.878
J09-J18 Influenza and pneumonia
0.000 0.123 0.877
J34.8 Other specified disorders of nose and nasal sinuses
0.000 0.124 0.876
F17.1 Harmful use
0.000 0.127 0.873
J18 Pneumonia, organism unspecified
0.000 0.135 0.865
Z97 Presence of other devices
0.000 0.136 0.864
J95-J99 Other diseases of the respiratory system
0.000 0.136 0.864
I25.2 Old myocardial infarction
0.000 0.137 0.863
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.139 0.861
Z83.7 Family history of diseases of the digestive system
0.000 0.140 0.860
I51.7 Cardiomegaly
0.000 0.154 0.846
I25.5 Ischaemic cardiomyopathy
0.000 0.155 0.845
Z88.4 Personal history of allergy to anaesthetic agent
0.000 0.158 0.842
I38 Endocarditis, valve unspecified
0.000 0.161 0.839
J18.1 Lobar pneumonia, unspecified
0.000 0.162 0.838
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.000 0.163 0.837
J34.2 Deviated nasal septum
0.000 0.170 0.830
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.000 0.171 0.829
J60-J70 Lung diseases due to external agents
0.000 0.173 0.827
E20-E35 Disorders of other endocrine glands
0.000 0.182 0.818
I44.1 Atrioventricular block, second degree
0.000 0.184 0.816
Z88.0 Personal history of allergy to penicillin
0.000 0.187 0.813
F10.3 Withdrawal state
0.000 0.188 0.812
J98 Other respiratory disorders
0.000 0.188 0.812
I21.4 Acute subendocardial myocardial infarction
0.000 0.188 0.812
Z95.0 Presence of cardiac pacemaker
0.000 0.189 0.811
Z97.8 Presence of other specified devices
0.000 0.192 0.808
I49.8 Other specified cardiac arrhythmias
0.000 0.194 0.806
J90-J94 Other diseases of pleura
0.000 0.197 0.803
F17.2 Dependence syndrome
0.000 0.198 0.802
I31 Other diseases of pericardium
0.000 0.199 0.801
I20.1 Angina pectoris with documented spasm
0.000 0.199 0.801
E89.0 Postprocedural hypothyroidism
0.000 0.201 0.799
E78.8 Other disorders of lipoprotein metabolism
0.000 0.206 0.794
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.211 0.789
Z88.1 Personal history of allergy to other antibiotic agents
0.000 0.214 0.786
I49.0 Ventricular fibrillation and flutter
0.000 0.217 0.783
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.220 0.780
I45.1 Other and unspecified right bundle-branch block
0.000 0.223 0.777
Z99.1 Dependence on respirator
0.000 0.227 0.773
I36 Nonrheumatic tricuspid valve disorders
0.000 0.229 0.771
E83.1 Disorders of iron metabolism
0.000 0.231 0.769
E05.9 Thyrotoxicosis, unspecified
0.000 0.233 0.767
E06 Thyroiditis
0.000 0.235 0.765
I49.1 Atrial premature depolarisation
0.000 0.238 0.762
F10.1 Harmful use
0.000 0.244 0.756
I47 Paroxysmal tachycardia
0.000 0.246 0.754
I51.8 Other ill-defined heart diseases
0.000 0.247 0.753
Z72.1 Alcohol use
0.000 0.248 0.752
I30 Acute pericarditis
0.000 0.250 0.750
F60-F69 Disorders of adult personality and behaviour
0.000 0.252 0.748
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.256 0.744
I49.5 Sick sinus syndrome
0.000 0.257 0.743
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.258 0.742
E88 Other metabolic disorders
0.000 0.261 0.739
J90 Pleural effusion, not elsewhere classified
0.000 0.261 0.739
I45.9 Conduction disorder, unspecified
0.000 0.262 0.738
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.267 0.733
I49.9 Cardiac arrhythmia, unspecified
0.000 0.268 0.732
E87.7 Fluid overload
0.000 0.269 0.731
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.270 0.730
J18.9 Pneumonia, unspecified
0.000 0.270 0.730
Z84 Family history of other conditions
0.000 0.273 0.727
Z74 Problems related to care-provider dependency
0.000 0.275 0.725
Z88.7 Personal history of allergy to serum and vaccine
0.000 0.277 0.723
J98.1 Pulmonary collapse
0.000 0.279 0.721
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.283 0.717
I46 Cardiac arrest
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.716
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.716
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.285 0.715
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.287 0.713
J18.0 Bronchopneumonia, unspecified
0.000 0.287 0.713
Z95.1 Presence of aortocoronary bypass graft
0.000 0.292 0.708
J34.1 Cyst and mucocele of nose and nasal sinus
0.000 0.294 0.706
E07 Other disorders of thyroid
0.000 0.294 0.706
I00-I02 Acute rheumatic fever
0.000 0.296 0.704
E84 Cystic fibrosis
0.000 0.296 0.704
E79 Disorders of purine and pyrimidine metabolism
0.000 0.296 0.704
E77 Disorders of glycoprotein metabolism
0.000 0.296 0.704
E76 Disorders of glycosaminoglycan metabolism
0.000 0.296 0.704
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.296 0.704
E74 Other disorders of carbohydrate metabolism
0.000 0.296 0.704
E72 Other disorders of amino-acid metabolism
0.000 0.296 0.704
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.296 0.704
E70 Disorders of aromatic amino-acid metabolism
0.000 0.296 0.704
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.296 0.704
I52 Other heart disorders in diseases classified elsewhere
0.000 0.296 0.704
I48 Atrial fibrillation and flutter
0.000 0.296 0.704
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.296 0.704
I41 Myocarditis in diseases classified elsewhere
0.000 0.296 0.704
I40 Acute myocarditis
0.000 0.296 0.704
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.296 0.704
I32 Pericarditis in diseases classified elsewhere
0.000 0.296 0.704
Z89 Acquired absence of limb
0.000 0.299 0.701
I49.3 Ventricular premature depolarisation
0.000 0.301 0.699
J34.0 Abscess, furuncle and carbuncle of nose
0.000 0.302 0.698
Z72.2 Drug use
0.000 0.302 0.698
I35 Nonrheumatic aortic valve disorders
0.000 0.302 0.698
E23 Hypofunction and other disorders of pituitary gland
0.000 0.305 0.695
I37 Pulmonary valve disorders
0.000 0.306 0.693
I25.3 Aneurysm of heart
0.000 0.307 0.692
I24 Other acute ischaemic heart diseases
0.000 0.308 0.692
I45.5 Other specified heart block
0.000 0.308 0.692
E78.6 Lipoprotein deficiency
0.000 0.309 0.691
E78.3 Hyperchylomicronaemia
0.000 0.309 0.691
E78.1 Pure hyperglyceridaemia
0.000 0.309 0.691
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.309 0.691
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.309 0.691
E83.8 Other disorders of mineral metabolism
0.000 0.309 0.691
E83.2 Disorders of zinc metabolism
0.000 0.309 0.691
E83.0 Disorders of copper metabolism
0.000 0.309 0.691
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.310 0.690
Z81 Family history of mental and behavioural disorders
0.000 0.311 0.689
J98.8 Other specified respiratory disorders
0.000 0.313 0.687
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.316 0.683
E00 Congenital iodine-deficiency syndrome
0.000 0.316 0.683
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.316 0.683
E87.4 Mixed disorder of acid-base balance
0.000 0.317 0.683
E89.3 Postprocedural hypopituitarism
0.000 0.318 0.682
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.319 0.681
I45.6 Preexcitation syndrome
0.000 0.323 0.677
I47.2 Ventricular tachycardia
0.000 0.326 0.674
I33 Acute and subacute endocarditis
0.000 0.327 0.673
E89.2 Postprocedural hypoparathyroidism
0.000 0.327 0.673
F99-F99 Unspecified mental disorder
0.000 0.328 0.672
Z97.5 Presence of (intra-uterine) contraceptive device
0.000 0.330 0.669
I44.2 Atrioventricular block, complete
0.000 0.331 0.669
J35 Chronic diseases of tonsils and adenoids
0.000 0.331 0.669
I49.2 Junctional premature depolarisation
0.000 0.331 0.668
I44.5 Left posterior fascicular block
0.000 0.332 0.668
I44.4 Left anterior fascicular block
0.000 0.332 0.668
J34.3 Hypertrophy of nasal turbinates
0.000 0.332 0.668
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.333 0.667
F70-F79 Mental retardation
0.000 0.333 0.667
F10.4 Withdrawal state with delirium
0.000 0.334 0.666
F10.2 Dependence syndrome
0.000 0.334 0.666
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.335 0.665
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.335 0.665
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.335 0.665
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.335 0.665
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.335 0.665
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.335 0.665
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.335 0.665
F11 Mental and behavioural disorders due to use of opioids
0.000 0.335 0.665
J92 Pleural plaque
0.000 0.336 0.664
E40-E46 Malnutrition
0.000 0.337 0.663
Z88.2 Personal history of allergy to sulphonamides
0.000 0.338 0.662
E03.5 Myxoedema coma
0.000 0.338 0.662
E03.4 Atrophy of thyroid (acquired)
0.000 0.338 0.662
E03.3 Postinfectious hypothyroidism
0.000 0.338 0.662
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.338 0.662
E03.1 Congenital hypothyroidism without goitre
0.000 0.338 0.662
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.338 0.662
Z76 Persons encountering health services in other circumstances
0.000 0.339 0.661
Z70 Counselling related to sexual attitude, behaviour and orientation
0.000 0.339 0.661
I31.9 Disease of pericardium, unspecified
0.000 0.340 0.660
E73 Lactose intolerance
0.000 0.341 0.658
Z72.9 Problem related to lifestyle, unspecified
0.000 0.343 0.657
Z72.8 Other problems related to lifestyle
0.000 0.343 0.657
Z72.6 Gambling and betting
0.000 0.343 0.657
Z72.5 High-risk sexual behaviour
0.000 0.343 0.657
Z72.4 Inappropriate diet and eating habits
0.000 0.343 0.657
Z72.3 Lack of physical exercise
0.000 0.343 0.657
I44.6 Other and unspecified fascicular block
0.000 0.345 0.655
E16 Other disorders of pancreatic internal secretion
0.000 0.346 0.654
I45.3 Trifascicular block
0.000 0.348 0.652
F10.0 Acute intoxication
0.000 0.349 0.651
F17.9 Unspecified mental and behavioural disorder
0.000 0.349 0.651
F17.8 Other mental and behavioural disorders
0.000 0.349 0.651
F17.7 Residual and late-onset psychotic disorder
0.000 0.349 0.651
F17.6 Amnesic syndrome
0.000 0.349 0.651
F17.5 Psychotic disorder
0.000 0.349 0.651
F17.4 Withdrawal state with delirium
0.000 0.349 0.651
F17.3 Withdrawal state
0.000 0.349 0.651
F17.0 Acute intoxication
0.000 0.349 0.651
Z99.3 Dependence on wheelchair
0.000 0.349 0.651
I51.6 Cardiovascular disease, unspecified
0.000 0.350 0.650
I51.5 Myocardial degeneration
0.000 0.350 0.650
I51.4 Myocarditis, unspecified
0.000 0.350 0.650
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.350 0.650
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.350 0.650
I51.0 Cardiac septal defect, acquired
0.000 0.350 0.650
E10-E14 Diabetes mellitus
0.000 0.351 0.649
I22 Subsequent myocardial infarction
0.000 0.352 0.648
F60 Specific personality disorders
0.000 0.354 0.646
E83.4 Disorders of magnesium metabolism
0.000 0.359 0.641
Z75 Problems related to medical facilities and other health care
0.000 0.359 0.641
Chapter XXII Codes for special purposes
0.000 0.359 0.641
I45.4 Nonspecific intraventricular block
0.000 0.360 0.640
I45.2 Bifascicular block
0.000 0.360 0.640
I45.0 Right fascicular block
0.000 0.360 0.640
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.360 0.640
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.361 0.638
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.361 0.638
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.361 0.638
E89.5 Postprocedural testicular hypofunction
0.000 0.361 0.638
E89.4 Postprocedural ovarian failure
0.000 0.361 0.638
E89.1 Postprocedural hypoinsulinaemia
0.000 0.361 0.638
Z83.6 Family history of diseases of the respiratory system
0.000 0.362 0.638
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.362 0.638
Z83.1 Family history of other infectious and parasitic diseases
0.000 0.362 0.638
Z83.0 Family history of human immunodeficiency virus [HIV]
0.000 0.362 0.638
J98.4 Other disorders of lung
0.000 0.362 0.638
E83.3 Disorders of phosphorus metabolism
0.000 0.363 0.637
J36 Peritonsillar abscess
0.000 0.363 0.637
I05-I09 Chronic rheumatic heart diseases
0.000 0.363 0.637
I99 Other and unspecified disorders of circulatory system
0.000 0.363 0.637
F10.9 Unspecified mental and behavioural disorder
0.000 0.364 0.636
F10.8 Other mental and behavioural disorders
0.000 0.364 0.636
F10.7 Residual and late-onset psychotic disorder
0.000 0.364 0.636
F10.6 Amnesic syndrome
0.000 0.364 0.636
F10.5 Psychotic disorder
0.000 0.364 0.636
E23.0 Hypopituitarism
0.000 0.364 0.636
J37 Chronic laryngitis and laryngotracheitis
0.000 0.364 0.635
E87.0 Hyperosmolality and hypernatraemia
0.000 0.365 0.634
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.366 0.634
I44.3 Other and unspecified atrioventricular block
0.000 0.366 0.634
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.000 0.369 0.631
E06.3 Autoimmune thyroiditis
0.000 0.370 0.630
I51.9 Heart disease, unspecified
0.000 0.370 0.630
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.000 0.371 0.629
J12 Viral pneumonia, not elsewhere classified
0.000 0.371 0.629
J09 Influenza due to certain identified influenza virus
0.000 0.371 0.629
Z83.5 Family history of eye and ear disorders
0.000 0.371 0.628
J32 Chronic sinusitis
0.000 0.372 0.628
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.372 0.628
J11 Influenza, virus not identified
0.000 0.377 0.623
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.380 0.620
J18.8 Other pneumonia, organism unspecified
0.000 0.380 0.620
J18.2 Hypostatic pneumonia, unspecified
0.000 0.380 0.620
Z97.3 Presence of spectacles and contact lenses
0.000 0.380 0.620
Z97.2 Presence of dental prosthetic device (complete)(partial)
0.000 0.380 0.620
Z97.1 Presence of artificial limb (complete)(partial)
0.000 0.380 0.620
J13 Pneumonia due to Streptococcus pneumoniae
0.000 0.380 0.620
J96 Respiratory failure, not elsewhere classified
0.000 0.380 0.619
Z97.4 Presence of external hearing-aid
0.000 0.382 0.618
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.382 0.618
F30-F39 Mood [affective] disorders
0.000 0.382 0.618
E21.0 Primary hyperparathyroidism
0.000 0.382 0.618
E05.8 Other thyrotoxicosis
0.000 0.383 0.617
E05.5 Thyroid crisis or storm
0.000 0.383 0.617
E05.4 Thyrotoxicosis factitia
0.000 0.383 0.617
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.383 0.617
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.383 0.617
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.383 0.617
J69 Pneumonitis due to solids and liquids
0.000 0.383 0.617
J35.0 Chronic tonsillitis
0.000 0.389 0.611
E10 Insulin-dependent diabetes mellitus
0.000 0.390 0.610
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.391 0.609
Z99.2 Dependence on renal dialysis
0.000 0.391 0.609
Z95.3 Presence of xenogenic heart valve
0.000 0.393 0.607
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.394 0.606
I35.1 Aortic (valve) insufficiency
0.000 0.395 0.605
E78.4 Other hyperlipidaemia
0.000 0.396 0.604
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.396 0.604
F52 Sexual dysfunction, not caused by organic disorder or disease
0.000 0.398 0.602
I46.9 Cardiac arrest, unspecified
0.000 0.399 0.601
F80-F89 Disorders of psychological development
0.000 0.399 0.601
Z99.9 Dependence on unspecified enabling machine and device
0.000 0.400 0.600
Z99.4 Dependence on artificial heart
0.000 0.400 0.600
Z99.0 Dependence on aspirator
0.000 0.400 0.600
I44.0 Atrioventricular block, first degree
0.000 0.402 0.598
J86 Pyothorax
0.000 0.403 0.597
E28 Ovarian dysfunction
0.000 0.405 0.595
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.405 0.594
E22 Hyperfunction of pituitary gland
0.000 0.406 0.594
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.406 0.594
J70 Respiratory conditions due to other external agents
0.000 0.407 0.593
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.407 0.593
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.407 0.593
J66 Airway disease due to specific organic dust
0.000 0.407 0.593
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.407 0.593
J62 Pneumoconiosis due to dust containing silica
0.000 0.407 0.593
J65 Pneumoconiosis associated with tuberculosis
0.000 0.407 0.593
J64 Unspecified pneumoconiosis
0.000 0.407 0.593
J60 Coalworker's pneumoconiosis
0.000 0.407 0.593
I31.3 Pericardial effusion (noninflammatory)
0.000 0.409 0.591
E34 Other endocrine disorders
0.000 0.410 0.590
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.414 0.586
E32 Diseases of thymus
0.000 0.414 0.586
E31 Polyglandular dysfunction
0.000 0.414 0.586
E30 Disorders of puberty, not elsewhere classified
0.000 0.414 0.586
E26 Hyperaldosteronism
0.000 0.414 0.586
E25 Adrenogenital disorders
0.000 0.414 0.586
E20 Hypoparathyroidism
0.000 0.414 0.586
Z74.0 Reduced mobility
0.000 0.415 0.584
I30.9 Acute pericarditis, unspecified
0.000 0.416 0.584
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.418 0.582
J98.6 Disorders of diaphragm
0.000 0.418 0.582
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.418 0.582
J98.3 Compensatory emphysema
0.000 0.418 0.582
J98.2 Interstitial emphysema
0.000 0.418 0.582
Z89.6 Acquired absence of leg above knee
0.000 0.419 0.581
I50 Heart failure
0.000 0.421 0.579
I31.8 Other specified diseases of pericardium
0.000 0.426 0.574
I31.2 Haemopericardium, not elsewhere classified
0.000 0.426 0.574
I31.1 Chronic constrictive pericarditis
0.000 0.426 0.574
I31.0 Chronic adhesive pericarditis
0.000 0.426 0.574
Z83.3 Family history of diabetes mellitus
0.000 0.427 0.573
J15 Bacterial pneumonia, not elsewhere classified
0.000 0.427 0.573
Z83.4 Family history of other endocrine, nutritional and metabolic diseases
0.000 0.429 0.571
E03.8 Other specified hypothyroidism
0.000 0.430 0.570
J17 Pneumonia in diseases classified elsewhere
0.000 0.431 0.569
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.433 0.567
Z73 Problems related to life-management difficulty
0.000 0.433 0.567
I25.4 Coronary artery aneurysm
0.000 0.434 0.566
E15 Nondiabetic hypoglycaemic coma
0.000 0.434 0.566
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.435 0.565
Z84.8 Family history of other specified conditions
0.000 0.440 0.560
Z95.2 Presence of prosthetic heart valve
0.000 0.442 0.557
E16.2 Hypoglycaemia, unspecified
0.000 0.443 0.557
E87.3 Alkalosis
0.000 0.444 0.556
J39 Other diseases of upper respiratory tract
0.000 0.444 0.556
E21.3 Hyperparathyroidism, unspecified
0.000 0.445 0.555
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.447 0.553
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.447 0.553
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.447 0.553
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.447 0.553
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.447 0.553
E29 Testicular dysfunction
0.000 0.449 0.551
F60.9 Personality disorder, unspecified
0.000 0.451 0.549
E06.9 Thyroiditis, unspecified
0.000 0.451 0.549
E06.5 Other chronic thyroiditis
0.000 0.451 0.549
E06.4 Drug-induced thyroiditis
0.000 0.451 0.549
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.451 0.549
E06.1 Subacute thyroiditis
0.000 0.451 0.549
E06.0 Acute thyroiditis
0.000 0.451 0.549
J32.8 Other chronic sinusitis
0.000 0.452 0.548
I45.8 Other specified conduction disorders
0.000 0.453 0.547
Chapter VIII Diseases of the ear and mastoid process
0.000 0.453 0.547
E10.1 With ketoacidosis
0.000 0.453 0.546
E24 Cushing's syndrome
0.000 0.455 0.545
J92.0 Pleural plaque with presence of asbestos
0.000 0.455 0.544
E87.6 Hypokalaemia
0.000 0.456 0.544
J20-J22 Other acute lower respiratory infections
0.000 0.460 0.539
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.462 0.538
I30.8 Other forms of acute pericarditis
0.000 0.462 0.538
I30.1 Infective pericarditis
0.000 0.462 0.538
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.462 0.538
F68 Other disorders of adult personality and behaviour
0.000 0.464 0.536
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.000 0.464 0.536
F65 Disorders of sexual preference
0.000 0.464 0.536
F63 Habit and impulse disorders
0.000 0.464 0.536
F62 Enduring personality changes, not attributable to brain damage and disease
0.000 0.464 0.536
F69 Unspecified disorder of adult personality and behaviour
0.000 0.464 0.536
F61 Mixed and other personality disorders
0.000 0.464 0.536
E65-E68 Obesity and other hyperalimentation
0.000 0.465 0.535
I07 Rheumatic tricuspid valve diseases
0.000 0.465 0.535
J30 Vasomotor and allergic rhinitis
0.000 0.465 0.535
Z89.5 Acquired absence of leg at or below knee
0.000 0.467 0.533
J85 Abscess of lung and mediastinum
0.000 0.468 0.532
E88.9 Metabolic disorder, unspecified
0.000 0.470 0.530
E88.8 Other specified metabolic disorders
0.000 0.470 0.530
E88.3 Tumour lysis syndrome
0.000 0.470 0.530
E88.2 Lipomatosis, not elsewhere classified
0.000 0.470 0.530
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.470 0.530
I47.0 Reentry ventricular arrhythmia
0.000 0.470 0.530
J80 Adult respiratory distress syndrome
0.000 0.471 0.529
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.000 0.471 0.529
E07.9 Disorder of thyroid, unspecified
0.000 0.471 0.529
J98.9 Respiratory disorder, unspecified
0.000 0.474 0.526
E85 Amyloidosis
0.001 0.474 0.525
E10.3 With ophthalmic complications
0.000 0.475 0.525
E50-E64 Other nutritional deficiencies
0.000 0.475 0.525
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.000 0.476 0.524
F51 Nonorganic sleep disorders
0.000 0.476 0.524
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.476 0.524
F55 Abuse of non-dependence-producing substances
0.000 0.476 0.524
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.000 0.476 0.524
J33 Nasal polyp
0.000 0.478 0.522
Z84.3 Family history of consanguinity
0.000 0.478 0.521
Z84.2 Family history of other diseases of the genito-urinary system
0.000 0.478 0.521
Z84.1 Family history of disorders of the kidney and ureter
0.000 0.478 0.521
Z84.0 Family history of diseases of the skin and subcutaneous tissue
0.000 0.478 0.521
F43 Reaction to severe stress, and adjustment disorders
0.000 0.479 0.521
Z74.9 Problem related to care-provider dependency, unspecified
0.000 0.480 0.520
Z74.8 Other problems related to care-provider dependency
0.000 0.480 0.520
Z74.3 Need for continuous supervision
0.000 0.480 0.520
Z74.2 Need for assistance at home and no other household member able to render care
0.000 0.480 0.520
Z74.1 Need for assistance with personal care
0.000 0.480 0.520
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I46.1 Sudden cardiac death, so described
0.000 0.486 0.514
I49.4 Other and unspecified premature depolarisation
0.000 0.487 0.512
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.489 0.511
E21.4 Other specified disorders of parathyroid gland
0.000 0.489 0.511
E21.2 Other hyperparathyroidism
0.000 0.489 0.511
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.489 0.511
J10 Influenza due to identified influenza virus
0.000 0.489 0.510
E86 Volume depletion
0.000 0.490 0.510
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.490 0.510
J91 Pleural effusion in conditions classified elsewhere
0.000 0.490 0.509
F52.2 Failure of genital response
0.000 0.490 0.509
F60.3 Emotionally unstable personality disorder
0.000 0.491 0.509
F31 Bipolar affective disorder
0.000 0.492 0.508
J92.9 Pleural plaque without asbestos
0.000 0.493 0.507
E07.8 Other specified disorders of thyroid
0.000 0.494 0.506
E07.1 Dyshormogenetic goitre
0.000 0.494 0.506
E07.0 Hypersecretion of calcitonin
0.000 0.494 0.506
I02 Rheumatic chorea
0.000 0.495 0.505
I01 Rheumatic fever with heart involvement
0.000 0.495 0.505
I00 Rheumatic fever without mention of heart involvement
0.000 0.495 0.505
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.495 0.505
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.495 0.505
E70.3 Albinism
0.000 0.495 0.505
E70.2 Disorders of tyrosine metabolism
0.000 0.495 0.505
E70.1 Other hyperphenylalaninaemias
0.000 0.495 0.505
E70.0 Classical phenylketonuria
0.000 0.495 0.505
E71.3 Disorders of fatty-acid metabolism
0.000 0.495 0.505
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.495 0.505
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.495 0.505
E71.0 Maple-syrup-urine disease
0.000 0.495 0.505
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.495 0.505
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.495 0.505
E72.5 Disorders of glycine metabolism
0.000 0.495 0.505
E72.4 Disorders of ornithine metabolism
0.000 0.495 0.505
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.495 0.505
E72.2 Disorders of urea cycle metabolism
0.000 0.495 0.505
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.495 0.505
E72.0 Disorders of amino-acid transport
0.000 0.495 0.505
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.495 0.505
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.495 0.505
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.495 0.505
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.495 0.505
E74.2 Disorders of galactose metabolism
0.000 0.495 0.505
E74.1 Disorders of fructose metabolism
0.000 0.495 0.505
E74.0 Glycogen storage disease
0.000 0.495 0.505
E75.6 Lipid storage disorder, unspecified
0.000 0.495 0.505
E75.5 Other lipid storage disorders
0.000 0.495 0.505
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.495 0.505
E75.3 Sphingolipidosis, unspecified
0.000 0.495 0.505
E75.2 Other sphingolipidosis
0.000 0.495 0.505
E75.1 Other gangliosidosis
0.000 0.495 0.505
E75.0 GM2 gangliosidosis
0.000 0.495 0.505
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.495 0.505
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.495 0.505
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.495 0.505
E76.2 Other mucopolysaccharidoses
0.000 0.495 0.505
E76.1 Mucopolysaccharidosis, type II
0.000 0.495 0.505

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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