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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs414390
log Bayes Factor = 42.8483
Chromosome 6   position 29,509,874  (GRCh37) Explore rs414390 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
N40 Hyperplasia of prostate
0.938 0.062 0.000
N42 Other disorders of prostate
0.930 0.070 0.000
N42.8 Other specified disorders of prostate
0.927 0.073 0.000
E03 Other hypothyroidism
0.000 0.077 0.923
E05.9 Thyrotoxicosis, unspecified
0.000 0.101 0.899
N42.2 Atrophy of prostate
0.898 0.102 0.000
N42.1 Congestion and haemorrhage of prostate
0.897 0.103 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.105 0.895
E00-E07 Disorders of thyroid gland
0.000 0.113 0.887
N40-N51 Diseases of male genital organs
0.887 0.113 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.136 0.864
N42.9 Disorder of prostate, unspecified
0.823 0.177 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.228 0.772
N43 Hydrocele and spermatocele
0.722 0.278 0.000
N44 Torsion of testis
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.338 0.662
E03.4 Atrophy of thyroid (acquired)
0.000 0.338 0.662
E03.3 Postinfectious hypothyroidism
0.000 0.338 0.662
E05.5 Thyroid crisis or storm
0.000 0.358 0.642
E05.4 Thyrotoxicosis factitia
0.000 0.358 0.642
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.358 0.642
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.358 0.642
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.364 0.636
E00 Congenital iodine-deficiency syndrome
0.000 0.364 0.636
N42.3 Dysplasia of prostate
0.635 0.365 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.629 0.371 0.000
E06 Thyroiditis
0.000 0.409 0.591
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.410 0.590
E03.8 Other specified hypothyroidism
0.000 0.422 0.578
N43.3 Hydrocele, unspecified
0.558 0.442 0.000
N43.2 Other hydrocele
0.547 0.453 0.000
N43.4 Spermatocele
0.538 0.462 0.000
N43.1 Infected hydrocele
0.532 0.468 0.000
N43.0 Encysted hydrocele
0.518 0.482 0.000
E03.1 Congenital hypothyroidism without goitre
0.000 0.496 0.504
N46 Male infertility
0.502 0.498 0.000
N50 Other disorders of male genital organs
0.497 0.503 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.483 0.517 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.523 0.476
E06.5 Other chronic thyroiditis
0.000 0.524 0.476
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.528 0.472
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.544 0.456
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.544 0.456
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.544 0.456
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.544 0.456
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.544 0.456
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.544 0.456
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.544 0.456
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.544 0.456
N51.8 Other disorders of male genital organs in diseases classified elsewhere
0.451 0.549 0.000
N51.1 Disorders of testis and epididymis in diseases classified elsewhere
0.451 0.549 0.000
N51.0 Disorders of prostate in diseases classified elsewhere
0.451 0.549 0.000
N50.9 Disorder of male genital organs, unspecified
0.445 0.555 0.000
N51.2 Balanitis in diseases classified elsewhere
0.444 0.555 0.000
N41 Inflammatory diseases of prostate
0.427 0.573 0.000
E06.4 Drug-induced thyroiditis
0.000 0.576 0.424
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.576 0.424
E06.0 Acute thyroiditis
0.000 0.576 0.424
E07 Other disorders of thyroid
0.000 0.585 0.414
E83 Disorders of mineral metabolism
0.000 0.594 0.406
E06.1 Subacute thyroiditis
0.000 0.603 0.397
E06.3 Autoimmune thyroiditis
0.000 0.605 0.395
E05.8 Other thyrotoxicosis
0.001 0.609 0.390
K90 Intestinal malabsorption
0.000 0.616 0.384
E83.5 Disorders of calcium metabolism
0.000 0.624 0.376
E06.9 Thyroiditis, unspecified
0.000 0.633 0.367
N50.1 Vascular disorders of male genital organs
0.366 0.634 0.000
N49.9 Inflammatory disorder of unspecified male genital organ
0.347 0.653 0.000
N49.0 Inflammatory disorders of seminal vesicle
0.347 0.653 0.000
N41.2 Abscess of prostate
0.338 0.662 0.000
N45 Orchitis and epididymitis
0.335 0.665 0.000
N42.0 Calculus of prostate
0.332 0.667 0.001
N49.8 Inflammatory disorders of other specified male genital organs
0.321 0.679 0.000
N49.1 Inflammatory disorders of spermatic cord, tunica vaginalis and vas deferens
0.313 0.687 0.000
N41.8 Other inflammatory diseases of prostate
0.312 0.688 0.000
N41.3 Prostatocystitis
0.306 0.694 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.702 0.297
E07.1 Dyshormogenetic goitre
0.000 0.703 0.297
E07.0 Hypersecretion of calcitonin
0.000 0.703 0.297
E83.8 Other disorders of mineral metabolism
0.000 0.708 0.291
E83.2 Disorders of zinc metabolism
0.000 0.708 0.291
E83.0 Disorders of copper metabolism
0.000 0.708 0.291
N49.2 Inflammatory disorders of scrotum
0.288 0.712 0.000
N41.0 Acute prostatitis
0.281 0.719 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.725 0.275
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.725 0.275
K90.1 Tropical sprue
0.000 0.725 0.275
K90.8 Other intestinal malabsorption
0.000 0.729 0.271
G35 Multiple sclerosis
0.000 0.729 0.271
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.752 0.248
E07.8 Other specified disorders of thyroid
0.000 0.760 0.240
N50.0 Atrophy of testis
0.223 0.777 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.780 0.220
N41.1 Chronic prostatitis
0.214 0.786 0.000
E83.3 Disorders of phosphorus metabolism
0.000 0.788 0.212
N41.9 Inflammatory disease of prostate, unspecified
0.205 0.795 0.000
E83.4 Disorders of magnesium metabolism
0.000 0.796 0.204
E07.9 Disorder of thyroid, unspecified
0.000 0.813 0.186
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess
0.169 0.830 0.000
K72.9 Hepatic failure, unspecified
0.000 0.872 0.128
M20.1 Hallux valgus (acquired)
0.108 0.892 0.000
K72 Hepatic failure, not elsewhere classified
0.000 0.892 0.108
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.108 0.892 0.000
E04 Other non-toxic goitre
0.000 0.906 0.094
K72.0 Acute and subacute hepatic failure
0.000 0.907 0.093
N50.8 Other specified disorders of male genital organs
0.083 0.917 0.000
K72.1 Chronic hepatic failure
0.000 0.921 0.079
K70-K77 Diseases of liver
0.000 0.922 0.078
K75 Other inflammatory liver diseases
0.000 0.924 0.076
E04.0 Non-toxic diffuse goitre
0.000 0.927 0.073
K75.4 Autoimmune hepatitis
0.000 0.929 0.071
E04.8 Other specified non-toxic goitre
0.000 0.932 0.067
K75.8 Other specified inflammatory liver diseases
0.000 0.934 0.066
K74 Fibrosis and cirrhosis of liver
0.000 0.934 0.066
G35-G37 Demyelinating diseases of the central nervous system
0.000 0.935 0.065
K73 Chronic hepatitis, not elsewhere classified
0.000 0.939 0.061
K74.0 Hepatic fibrosis
0.000 0.940 0.060
K75.9 Inflammatory liver disease, unspecified
0.000 0.942 0.058
K71 Toxic liver disease
0.000 0.942 0.058
K77 Liver disorders in diseases classified elsewhere
0.000 0.944 0.056
N47 Redundant prepuce, phimosis and paraphimosis
0.056 0.944 0.000
K75.2 Nonspecific reactive hepatitis
0.000 0.946 0.054
K75.1 Phlebitis of portal vein
0.000 0.946 0.054
K73.9 Chronic hepatitis, unspecified
0.000 0.947 0.052
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.948 0.052
K75.0 Abscess of liver
0.000 0.948 0.052
K74.5 Biliary cirrhosis, unspecified
0.000 0.951 0.049
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.953 0.047
K74.4 Secondary biliary cirrhosis
0.000 0.953 0.047
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.953 0.047
K74.1 Hepatic sclerosis
0.000 0.953 0.047
G36 Other acute disseminated demyelination
0.000 0.953 0.047
K71.0 Toxic liver disease with cholestasis
0.000 0.953 0.046
K74.3 Primary biliary cirrhosis
0.000 0.955 0.045
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.956 0.044
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.956 0.044
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.958 0.042
K71.9 Toxic liver disease, unspecified
0.000 0.958 0.041
K71.8 Toxic liver disease with other disorders of liver
0.000 0.958 0.041
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.958 0.041
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.958 0.041
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.958 0.041
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.958 0.041
K71.2 Toxic liver disease with acute hepatitis
0.000 0.958 0.041
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.960 0.040
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.960 0.040
K74.6 Other and unspecified cirrhosis of liver
0.000 0.960 0.040
K76.6 Portal hypertension
0.000 0.961 0.039
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.963 0.037
K76 Other diseases of liver
0.000 0.963 0.037
C44.3 Skin of other and unspecified parts of face
0.000 0.965 0.035
G36.0 Neuromyelitis optica [Devic]
0.000 0.965 0.034
G36.9 Acute disseminated demyelination, unspecified
0.000 0.966 0.034
G36.8 Other specified acute disseminated demyelination
0.000 0.966 0.034
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.000 0.966 0.034
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.966 0.033
M45.X9 Ankylosing spondylitis (Site unspecified)
0.031 0.969 0.000
K90-K93 Other diseases of the digestive system
0.000 0.969 0.031
M20.3 Other deformity of hallux (acquired)
0.029 0.971 0.000
S62.20 Fracture of first metacarpal bone (closed)
0.029 0.971 0.000
M20 Acquired deformities of fingers and toes
0.027 0.973 0.000
K76.5 Hepatic veno-occlusive disease
0.000 0.973 0.026
K76.4 Peliosis hepatis
0.000 0.973 0.026
K76.2 Central haemorrhagic necrosis of liver
0.000 0.973 0.026
N48 Other disorders of penis
0.026 0.974 0.000
K76.1 Chronic passive congestion of liver
0.000 0.975 0.025
M35.0 Sicca syndrome [Sjogren]
0.000 0.975 0.025
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.976 0.024
K76.7 Hepatorenal syndrome
0.000 0.976 0.023
E70-E90 Metabolic disorders
0.000 0.977 0.023
E04.1 Non-toxic single thyroid nodule
0.000 0.977 0.023
K76.3 Infarction of liver
0.000 0.977 0.023
G37 Other demyelinating diseases of central nervous system
0.001 0.978 0.022
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.978 0.022
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.978 0.022
E89.0 Postprocedural hypothyroidism
0.000 0.978 0.022
M20.6 Acquired deformity of toe(s), unspecified
0.022 0.978 0.000
J38.4 Oedema of larynx
0.000 0.979 0.021
K11.5 Sialolithiasis
0.020 0.980 0.000
N48.5 Ulcer of penis
0.020 0.980 0.000
K70 Alcoholic liver disease
0.000 0.981 0.019
J38.3 Other diseases of vocal cords
0.000 0.981 0.019
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.000 0.981 0.019
M45 Ankylosing spondylitis
0.019 0.981 0.000
N48.3 Priapism
0.018 0.982 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.982 0.018
E89.3 Postprocedural hypopituitarism
0.000 0.982 0.018
G37.8 Other specified demyelinating diseases of central nervous system
0.000 0.983 0.017
N48.1 Balanoposthitis
0.017 0.983 0.000
K76.9 Liver disease, unspecified
0.000 0.983 0.017
E84 Cystic fibrosis
0.000 0.983 0.017
E76 Disorders of glycosaminoglycan metabolism
0.000 0.983 0.017
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.983 0.017
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.983 0.017
E89.1 Postprocedural hypoinsulinaemia
0.000 0.984 0.016
E40-E46 Malnutrition
0.000 0.984 0.016
G37.5 Concentric sclerosis [Balo]
0.001 0.984 0.016
G37.4 Subacute necrotising myelitis
0.001 0.984 0.016
G37.2 Central pontine myelinolysis
0.001 0.984 0.016
G37.1 Central demyelination of corpus callosum
0.001 0.984 0.016
G37.0 Diffuse sclerosis
0.001 0.984 0.016
C50.8 Overlapping lesion of breast
0.016 0.984 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.984 0.016
K93.1 Megacolon in Chagas' disease
0.000 0.984 0.016
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.984 0.016
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.984 0.016
E89.5 Postprocedural testicular hypofunction
0.000 0.984 0.016
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.016 0.984 0.000
E70 Disorders of aromatic amino-acid metabolism
0.000 0.984 0.016
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.984 0.016
J38.7 Other diseases of larynx
0.000 0.984 0.016
J38.2 Nodules of vocal cords
0.000 0.984 0.016
E74 Other disorders of carbohydrate metabolism
0.000 0.984 0.016
E77 Disorders of glycoprotein metabolism
0.000 0.984 0.015
J38.1 Polyp of vocal cord and larynx
0.000 0.985 0.015
S62.2 Fracture of first metacarpal bone
0.015 0.985 0.000
K70.1 Alcoholic hepatitis
0.000 0.985 0.015
E72 Other disorders of amino-acid metabolism
0.000 0.985 0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.985 0.014
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.014 0.986 0.000
E89.4 Postprocedural ovarian failure
0.000 0.986 0.014
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.986 0.014
E79 Disorders of purine and pyrimidine metabolism
0.000 0.986 0.014
N48.9 Disorder of penis, unspecified
0.014 0.986 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.014 0.986 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.014 0.986 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.014 0.986 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.014 0.986 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.014 0.986 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.014 0.986 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.986 0.013
N48.6 Balanitis xerotica obliterans
0.013 0.987 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.013 0.987 0.000
J38.5 Laryngeal spasm
0.000 0.987 0.013
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.987 0.013
J38.6 Stenosis of larynx
0.000 0.987 0.013
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.987 0.013
R01.1 Cardiac murmur, unspecified
0.013 0.987 0.000
K70.0 Alcoholic fatty liver
0.000 0.987 0.013
M89.94 Disorder of bone, unspecified (Hand)
0.013 0.987 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.988 0.012
E84.8 Cystic fibrosis with other manifestations
0.000 0.988 0.012
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.988 0.012
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.988 0.012
E71.3 Disorders of fatty-acid metabolism
0.000 0.988 0.012
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.988 0.012
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.988 0.012
E71.0 Maple-syrup-urine disease
0.000 0.988 0.012
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.988 0.012
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.988 0.012
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.988 0.012
E76.2 Other mucopolysaccharidoses
0.000 0.988 0.012
E76.1 Mucopolysaccharidosis, type II
0.000 0.988 0.012
E76.0 Mucopolysaccharidosis, type I
0.000 0.988 0.012
E73 Lactose intolerance
0.001 0.988 0.012
N48.0 Leukoplakia of penis
0.012 0.988 0.000
M89.9 Disorder of bone, unspecified
0.012 0.988 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.988 0.012
E45 Retarded development following protein-energy malnutrition
0.000 0.988 0.012
E43 Unspecified severe protein-energy malnutrition
0.000 0.988 0.012
E42 Marasmic kwashiorkor
0.000 0.988 0.012
E41 Nutritional marasmus
0.000 0.988 0.012
E40 Kwashiorkor
0.000 0.988 0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.988 0.012
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.988 0.012
E70.2 Disorders of tyrosine metabolism
0.000 0.988 0.012
E70.1 Other hyperphenylalaninaemias
0.000 0.988 0.012
E70.0 Classical phenylketonuria
0.000 0.988 0.012
M45.X2 Ankylosing spondylitis (Cervical region)
0.012 0.988 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.012 0.988 0.000
E80.1 Porphyria cutanea tarda
0.000 0.988 0.012
E74.0 Glycogen storage disease
0.000 0.988 0.011
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.988 0.011
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.988 0.011
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.988 0.011
E74.2 Disorders of galactose metabolism
0.000 0.988 0.011
E74.1 Disorders of fructose metabolism
0.000 0.988 0.011
Z99.1 Dependence on respirator
0.012 0.988 0.000
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.989 0.011
E77.1 Defects in glycoprotein degradation
0.000 0.989 0.011
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.989 0.011
K70.9 Alcoholic liver disease, unspecified
0.000 0.989 0.011
M89 Other disorders of bone
0.011 0.989 0.000
N48.2 Other inflammatory disorders of penis
0.011 0.989 0.000
S62.21 Fracture of first metacarpal bone (open)
0.011 0.989 0.000
M94.88 Other specified disorders of cartilage (Other)
0.011 0.989 0.000
M89.0 Algoneurodystrophy
0.011 0.989 0.000
E70.3 Albinism
0.000 0.989 0.011
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.989 0.011
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.011 0.989 0.000
E80.2 Other porphyria
0.000 0.989 0.011
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.989 0.011
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.989 0.011
E72.5 Disorders of glycine metabolism
0.000 0.989 0.011
E72.4 Disorders of ornithine metabolism
0.000 0.989 0.011
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.989 0.011
E72.2 Disorders of urea cycle metabolism
0.000 0.989 0.011
K70.4 Alcoholic hepatic failure
0.000 0.989 0.011
M20.5 Other deformities of toe(s) (acquired)
0.011 0.989 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.989 0.011
E75.6 Lipid storage disorder, unspecified
0.000 0.989 0.010
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.989 0.010
E75.3 Sphingolipidosis, unspecified
0.000 0.989 0.010
E75.1 Other gangliosidosis
0.000 0.989 0.010
E75.0 GM2 gangliosidosis
0.000 0.989 0.010
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.989 0.010
E80.5 Crigler-Najjar syndrome
0.000 0.989 0.010
E80.3 Defects of catalase and peroxydase
0.000 0.989 0.010
E80.0 Hereditary erythropoietic porphyria
0.000 0.989 0.010
M89.07 Algoneurodystrophy (Ankle and foot)
0.010 0.990 0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.990 0.010
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.990 0.010
E79.1 Lesch-Nyhan syndrome
0.000 0.990 0.010
M62.8 Other specified disorders of muscle
0.010 0.990 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.990 0.010
K11 Diseases of salivary glands
0.010 0.990 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.010 0.990 0.000
E75.2 Other sphingolipidosis
0.000 0.990 0.010
E77.8 Other disorders of glycoprotein metabolism
0.000 0.990 0.010
M62.88 Other specified disorders of muscle (Other)
0.010 0.990 0.000
M89.03 Algoneurodystrophy (Forearm)
0.010 0.990 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.990 0.010
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.010 0.990 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.990 0.010
M62 Other disorders of muscle
0.010 0.990 0.000
K11.2 Sialoadenitis
0.010 0.990 0.000
M89.5 Osteolysis
0.009 0.991 0.000
E72.0 Disorders of amino-acid transport
0.000 0.991 0.009
E88 Other metabolic disorders
0.000 0.991 0.009
E75.5 Other lipid storage disorders
0.000 0.991 0.009
E73.8 Other lactose intolerance
0.001 0.991 0.009
E73.1 Secondary lactase deficiency
0.001 0.991 0.009
E73.0 Congenital lactase deficiency
0.001 0.991 0.009
M89.99 Disorder of bone, unspecified (Site unspecified)
0.009 0.991 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.009 0.991 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.009 0.991 0.000
M89.3 Hypertrophy of bone
0.009 0.991 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.991 0.009
E44.0 Moderate protein-energy malnutrition
0.000 0.991 0.009
M89.04 Algoneurodystrophy (Hand)
0.009 0.991 0.000
K11.7 Disturbances of salivary secretion
0.009 0.991 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.009 0.991 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.009 0.991 0.000
J38.0 Paralysis of vocal cords and larynx
0.000 0.991 0.009
E80.6 Other disorders of bilirubin metabolism
0.000 0.991 0.008
M20.0 Deformity of finger(s)
0.009 0.991 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.008 0.991 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.008 0.991 0.000
M89.6 Osteopathy after poliomyelitis
0.008 0.992 0.000
M89.2 Other disorders of bone development and growth
0.008 0.992 0.000
M89.1 Epiphyseal arrest
0.008 0.992 0.000
M21.3 Wrist or foot drop (acquired)
0.008 0.992 0.000
E86 Volume depletion
0.000 0.992 0.008
E65-E68 Obesity and other hyperalimentation
0.000 0.992 0.008
I84.6 Residual haemorrhoidal skin tags
0.000 0.992 0.008
M89.09 Algoneurodystrophy (Site unspecified)
0.008 0.992 0.000
M89.08 Algoneurodystrophy (Other)
0.008 0.992 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.008 0.992 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.008 0.992 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.008 0.992 0.000
M82.1 Osteoporosis in endocrine disorders
0.008 0.992 0.000
E50-E64 Other nutritional deficiencies
0.000 0.992 0.008
M62.6 Muscle strain
0.008 0.992 0.000
M89.98 Disorder of bone, unspecified (Other)
0.008 0.992 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.008 0.992 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.008 0.992 0.000
M62.4 Contracture of muscle
0.008 0.992 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.008 0.992 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.008 0.992 0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)
0.008 0.992 0.000
M84 Disorders of continuity of bone
0.008 0.992 0.000
M89.8 Other specified disorders of bone
0.008 0.992 0.000
H34.8 Other retinal vascular occlusions
0.000 0.992 0.008
M62.89 Other specified disorders of muscle (Site unspecified)
0.008 0.992 0.000
M94.8 Other specified disorders of cartilage
0.008 0.992 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.008 0.992 0.000
M82 Osteoporosis in diseases classified elsewhere
0.008 0.992 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.007 0.992 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.001 0.992 0.007
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.001 0.992 0.007
K11.3 Abscess of salivary gland
0.007 0.992 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.008 0.992 0.000
K11.4 Fistula of salivary gland
0.007 0.992 0.000
K11.0 Atrophy of salivary gland
0.007 0.992 0.000
M89.56 Osteolysis (Lower leg)
0.007 0.992 0.000
E88.8 Other specified metabolic disorders
0.000 0.992 0.007
M60-M63 Disorders of muscles
0.007 0.992 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.007 0.992 0.000
M62.0 Diastasis of muscle
0.007 0.992 0.000
M80-M85 Disorders of bone density and structure
0.007 0.993 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.001 0.993 0.007
K11.9 Disease of salivary gland, unspecified
0.007 0.993 0.000
E80.4 Gilbert's syndrome
0.000 0.993 0.007
M62.3 Immobility syndrome (paraplegic)
0.007 0.993 0.000
M62.2 Ischaemic infarction of muscle
0.007 0.993 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.007 0.993 0.000
M62.81 Other specified disorders of muscle (Shoulder region)
0.007 0.993 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.000 0.993 0.007
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.993 0.007
K11.1 Hypertrophy of salivary gland
0.007 0.993 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.007 0.993 0.000
M89.59 Osteolysis (Site unspecified)
0.007 0.993 0.000
M89.58 Osteolysis (Other)
0.007 0.993 0.000
M89.57 Osteolysis (Ankle and foot)
0.007 0.993 0.000
M89.54 Osteolysis (Hand)
0.007 0.993 0.000
M89.53 Osteolysis (Forearm)
0.007 0.993 0.000
M89.52 Osteolysis (Upper arm)
0.007 0.993 0.000
M89.51 Osteolysis (Shoulder region)
0.007 0.993 0.000
M89.50 Osteolysis (Multiple sites)
0.007 0.993 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.007 0.993 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.007 0.993 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.007 0.993 0.000
M89.81 Other specified disorders of bone (Shoulder region)
0.007 0.993 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.993 0.007
N60.1 Diffuse cystic mastopathy
0.000 0.993 0.007
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.007 0.993 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.007 0.993 0.000
M62.9 Disorder of muscle, unspecified
0.007 0.993 0.000
M62.46 Contracture of muscle (Lower leg)
0.007 0.993 0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)
0.007 0.993 0.000
M94 Other disorders of cartilage
0.007 0.993 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.007 0.993 0.000
M85 Other disorders of bone density and structure
0.007 0.993 0.000
R01 Cardiac murmurs and other cardiac sounds
0.007 0.993 0.000
M84.2 Delayed union of fracture
0.007 0.993 0.000
M89.38 Hypertrophy of bone (Other)
0.007 0.993 0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
M45-M49 Spondylopathies
0.007 0.993 0.000
K11.6 Mucocele of salivary gland
0.007 0.993 0.000
M86-M90 Other osteopathies
0.007 0.993 0.000
M89.39 Hypertrophy of bone (Site unspecified)
0.006 0.993 0.000
M89.36 Hypertrophy of bone (Lower leg)
0.006 0.993 0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.006 0.993 0.000
M89.34 Hypertrophy of bone (Hand)
0.006 0.993 0.000
M89.33 Hypertrophy of bone (Forearm)
0.006 0.993 0.000
M89.32 Hypertrophy of bone (Upper arm)
0.006 0.993 0.000
M89.31 Hypertrophy of bone (Shoulder region)
0.006 0.993 0.000
M89.30 Hypertrophy of bone (Multiple sites)
0.006 0.993 0.000
M62.65 Muscle strain (Pelvic region and thigh)
0.007 0.993 0.000
E88.9 Metabolic disorder, unspecified
0.000 0.993 0.006
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.006 0.993 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.006 0.993 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.006 0.993 0.000
N48.8 Other specified disorders of penis
0.006 0.993 0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)
0.006 0.993 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.993 0.007
M62.84 Other specified disorders of muscle (Hand)
0.006 0.993 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.006 0.994 0.000
Chapter XI Diseases of the digestive system
0.000 0.994 0.006
M62.86 Other specified disorders of muscle (Lower leg)
0.006 0.994 0.000
M62.66 Muscle strain (Lower leg)
0.006 0.994 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.006 0.994 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.006 0.994 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.006 0.994 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.006 0.994 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.006 0.994 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.006 0.994 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.006 0.994 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.006 0.994 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.006 0.994 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.006 0.994 0.000
E88.3 Tumour lysis syndrome
0.000 0.994 0.006
E58 Dietary calcium deficiency
0.000 0.994 0.006
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.006 0.994 0.000
M99 Biomechanical lesions, not elsewhere classified
0.006 0.994 0.000
M91-M94 Chondropathies
0.006 0.994 0.000
M89.19 Epiphyseal arrest (Site unspecified)
0.006 0.994 0.000
M89.18 Epiphyseal arrest (Other)
0.006 0.994 0.000
M89.17 Epiphyseal arrest (Ankle and foot)
0.006 0.994 0.000
M89.16 Epiphyseal arrest (Lower leg)
0.006 0.994 0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)
0.006 0.994 0.000
M89.14 Epiphyseal arrest (Hand)
0.006 0.994 0.000
M89.13 Epiphyseal arrest (Forearm)
0.006 0.994 0.000
M89.12 Epiphyseal arrest (Upper arm)
0.006 0.994 0.000
M89.11 Epiphyseal arrest (Shoulder region)
0.006 0.994 0.000
M89.10 Epiphyseal arrest (Multiple sites)
0.006 0.994 0.000
M89.29 Other disorders of bone development and growth (Site unspecified)
0.006 0.994 0.000
M89.28 Other disorders of bone development and growth (Other)
0.006 0.994 0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)
0.006 0.994 0.000
M89.26 Other disorders of bone development and growth (Lower leg)
0.006 0.994 0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)
0.006 0.994 0.000
M89.24 Other disorders of bone development and growth (Hand)
0.006 0.994 0.000
M89.23 Other disorders of bone development and growth (Forearm)
0.006 0.994 0.000
M89.22 Other disorders of bone development and growth (Upper arm)
0.006 0.994 0.000
M89.21 Other disorders of bone development and growth (Shoulder region)
0.006 0.994 0.000
M89.20 Other disorders of bone development and growth (Multiple sites)
0.006 0.994 0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)
0.006 0.994 0.000
M89.68 Osteopathy after poliomyelitis (Other)
0.006 0.994 0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)
0.006 0.994 0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)
0.006 0.994 0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)
0.006 0.994 0.000
M89.64 Osteopathy after poliomyelitis (Hand)
0.006 0.994 0.000
M89.63 Osteopathy after poliomyelitis (Forearm)
0.006 0.994 0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)
0.006 0.994 0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)
0.006 0.994 0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)
0.006 0.994 0.000
M62.68 Muscle strain (Other)
0.006 0.994 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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