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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4148871
log Bayes Factor = 16.8904
Chromosome 6   position 32,803,316  (GRCh37) Explore rs4148871 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.988 0.012 0.000
G37 Other demyelinating diseases of central nervous system
0.986 0.014 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.967 0.033 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.908 0.092 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.886 0.114 0.000
G36 Other acute disseminated demyelination
0.744 0.256 0.000
G37.5 Concentric sclerosis [Balo]
0.707 0.293 0.000
G37.4 Subacute necrotising myelitis
0.707 0.293 0.000
G37.2 Central pontine myelinolysis
0.707 0.293 0.000
G37.1 Central demyelination of corpus callosum
0.707 0.293 0.000
G37.0 Diffuse sclerosis
0.707 0.293 0.000
G36.0 Neuromyelitis optica [Devic]
0.569 0.430 0.000
G36.9 Acute disseminated demyelination, unspecified
0.534 0.466 0.000
G36.8 Other specified acute disseminated demyelination
0.534 0.466 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.534 0.466 0.000
I10 Essential (primary) hypertension
0.000 0.478 0.522
E03.9 Hypothyroidism, unspecified
0.000 0.536 0.464
E83.1 Disorders of iron metabolism
0.448 0.552 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.565 0.435
E03 Other hypothyroidism
0.000 0.567 0.433
E10.9 Without complications
0.000 0.572 0.428
E10-E14 Diabetes mellitus
0.000 0.584 0.416
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.597 0.403
E00-E07 Disorders of thyroid gland
0.000 0.598 0.402
E10.3 With ophthalmic complications
0.000 0.598 0.402
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.624 0.376
E10.1 With ketoacidosis
0.000 0.633 0.367
E10.8 With unspecified complications
0.000 0.634 0.366
E16 Other disorders of pancreatic internal secretion
0.000 0.643 0.357
E40-E46 Malnutrition
0.000 0.644 0.355
E11 Non-insulin-dependent diabetes mellitus
0.000 0.653 0.347
E03.8 Other specified hypothyroidism
0.000 0.657 0.343
E10.4 With neurological complications
0.000 0.666 0.334
E10.6 With other specified complications
0.000 0.670 0.330
E10.2 With renal complications
0.000 0.675 0.325
E46 Unspecified protein-energy malnutrition
0.000 0.679 0.321
E10.5 With peripheral circulatory complications
0.000 0.679 0.321
E16.1 Other hypoglycaemia
0.000 0.682 0.318
E11.1 With ketoacidosis
0.000 0.683 0.317
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.684 0.316
E10.7 With multiple complications
0.000 0.688 0.312
E03.5 Myxoedema coma
0.000 0.689 0.311
E03.4 Atrophy of thyroid (acquired)
0.000 0.689 0.311
E03.3 Postinfectious hypothyroidism
0.000 0.689 0.311
E03.1 Congenital hypothyroidism without goitre
0.000 0.689 0.311
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.689 0.311
E10.0 With coma
0.000 0.691 0.309
E65-E68 Obesity and other hyperalimentation
0.000 0.691 0.309
E16.2 Hypoglycaemia, unspecified
0.000 0.699 0.301
E13 Other specified diabetes mellitus
0.000 0.700 0.300
E12 Malnutrition-related diabetes mellitus
0.000 0.702 0.298
E20-E35 Disorders of other endocrine glands
0.000 0.706 0.294
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.709 0.291
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.711 0.289
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.711 0.289
E00 Congenital iodine-deficiency syndrome
0.000 0.711 0.289
E11.8 With unspecified complications
0.000 0.714 0.286
E11.5 With peripheral circulatory complications
0.000 0.714 0.286
E11.9 Without complications
0.000 0.717 0.283
E15 Nondiabetic hypoglycaemic coma
0.000 0.730 0.270
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.738 0.262
E11.6 With other specified complications
0.000 0.741 0.259
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.744 0.256
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.744 0.256
E16.4 Abnormal secretion of gastrin
0.000 0.744 0.256
E16.3 Increased secretion of glucagon
0.000 0.744 0.256
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.745 0.255
E45 Retarded development following protein-energy malnutrition
0.000 0.745 0.255
E43 Unspecified severe protein-energy malnutrition
0.000 0.745 0.255
E42 Marasmic kwashiorkor
0.000 0.745 0.255
E41 Nutritional marasmus
0.000 0.745 0.255
E40 Kwashiorkor
0.000 0.745 0.255
E06 Thyroiditis
0.000 0.749 0.251
E11.7 With multiple complications
0.000 0.751 0.249
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.757 0.243
E21.0 Primary hyperparathyroidism
0.000 0.758 0.242
E29 Testicular dysfunction
0.000 0.764 0.236
E05.8 Other thyrotoxicosis
0.000 0.766 0.233
E65 Localised adiposity
0.000 0.768 0.232
E66 Obesity
0.000 0.768 0.232
E07 Other disorders of thyroid
0.000 0.776 0.223
E11.3 With ophthalmic complications
0.000 0.777 0.223
E67 Other hyperalimentation
0.000 0.778 0.222
E68 Sequelae of hyperalimentation
0.000 0.778 0.222
K90 Intestinal malabsorption
0.000 0.780 0.220
E22 Hyperfunction of pituitary gland
0.000 0.781 0.219
E11.0 With coma
0.000 0.781 0.219
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.781 0.218
E13.9 Without complications
0.000 0.783 0.217
E05.9 Thyrotoxicosis, unspecified
0.000 0.784 0.216
E13.8 With unspecified complications
0.000 0.785 0.215
E13.7 With multiple complications
0.000 0.785 0.215
E13.6 With other specified complications
0.000 0.785 0.215
E13.5 With peripheral circulatory complications
0.000 0.785 0.215
E13.4 With neurological complications
0.000 0.785 0.215
E13.3 With ophthalmic complications
0.000 0.785 0.215
E13.2 With renal complications
0.000 0.785 0.215
E13.1 With ketoacidosis
0.000 0.785 0.215
E13.0 With coma
0.000 0.785 0.215
E34 Other endocrine disorders
0.000 0.785 0.215
E12.9 Without complications
0.000 0.786 0.214
E12.8 With unspecified complications
0.000 0.786 0.214
E12.7 With multiple complications
0.000 0.786 0.214
E12.6 With other specified complications
0.000 0.786 0.214
E12.5 With peripheral circulatory complications
0.000 0.786 0.214
E12.4 With neurological complications
0.000 0.786 0.214
E12.3 With ophthalmic complications
0.000 0.786 0.214
E12.2 With renal complications
0.000 0.786 0.214
E12.1 With ketoacidosis
0.000 0.786 0.214
E12.0 With coma
0.000 0.786 0.214
E66.9 Obesity, unspecified
0.000 0.789 0.211
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.789 0.211
E32 Diseases of thymus
0.000 0.789 0.211
E31 Polyglandular dysfunction
0.000 0.789 0.211
E30 Disorders of puberty, not elsewhere classified
0.000 0.789 0.211
E25 Adrenogenital disorders
0.000 0.789 0.211
E24 Cushing's syndrome
0.000 0.790 0.210
E11.2 With renal complications
0.000 0.792 0.208
E05.5 Thyroid crisis or storm
0.000 0.793 0.207
E05.4 Thyrotoxicosis factitia
0.000 0.793 0.207
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.793 0.207
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.793 0.207
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.793 0.207
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.793 0.207
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.793 0.207
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.793 0.207
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.793 0.207
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.793 0.207
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.793 0.207
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.793 0.207
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.800 0.200
E06.3 Autoimmune thyroiditis
0.000 0.803 0.197
E23 Hypofunction and other disorders of pituitary gland
0.000 0.804 0.196
E29.1 Testicular hypofunction
0.000 0.805 0.195
E26 Hyperaldosteronism
0.000 0.806 0.194
E14 Unspecified diabetes mellitus
0.000 0.806 0.194
E28 Ovarian dysfunction
0.000 0.808 0.192
E20 Hypoparathyroidism
0.000 0.810 0.190
E21.4 Other specified disorders of parathyroid gland
0.000 0.812 0.188
E21.2 Other hyperparathyroidism
0.000 0.812 0.188
I10-I15 Hypertensive diseases
0.000 0.813 0.187
E44.1 Mild protein-energy malnutrition
0.000 0.817 0.183
E44.0 Moderate protein-energy malnutrition
0.000 0.817 0.183
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.819 0.180
E06.4 Drug-induced thyroiditis
0.000 0.820 0.180
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.820 0.180
E06.1 Subacute thyroiditis
0.000 0.820 0.180
E06.0 Acute thyroiditis
0.000 0.820 0.180
E22.0 Acromegaly and pituitary gigantism
0.000 0.821 0.179
E34.8 Other specified endocrine disorders
0.000 0.821 0.179
E22.1 Hyperprolactinaemia
0.000 0.823 0.177
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.824 0.176
E21.3 Hyperparathyroidism, unspecified
0.000 0.828 0.172
E29.9 Testicular dysfunction, unspecified
0.000 0.831 0.169
E29.8 Other testicular dysfunction
0.000 0.831 0.169
E29.0 Testicular hyperfunction
0.000 0.831 0.169
E07.8 Other specified disorders of thyroid
0.000 0.832 0.168
E66.1 Drug-induced obesity
0.000 0.833 0.167
E14.4 With neurological complications
0.000 0.837 0.163
E07.1 Dyshormogenetic goitre
0.000 0.839 0.160
E07.0 Hypersecretion of calcitonin
0.000 0.839 0.160
E67.8 Other specified hyperalimentation
0.000 0.841 0.159
E67.3 Hypervitaminosis D
0.000 0.841 0.159
E67.2 Megavitamin-B6 syndrome
0.000 0.841 0.159
E67.1 Hypercarotenaemia
0.000 0.841 0.159
E67.0 Hypervitaminosis A
0.000 0.841 0.159
E14.3 With ophthalmic complications
0.000 0.841 0.159
E23.7 Disorder of pituitary gland, unspecified
0.000 0.841 0.159
K90.3 Pancreatic steatorrhoea
0.000 0.842 0.158
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.842 0.158
K90.1 Tropical sprue
0.000 0.842 0.158
E24.0 Pituitary-dependent Cushing's disease
0.000 0.842 0.158
E66.0 Obesity due to excess calories
0.000 0.842 0.158
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.842 0.157
E22.8 Other hyperfunction of pituitary gland
0.000 0.842 0.157
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.845 0.155
E34.9 Endocrine disorder, unspecified
0.000 0.845 0.155
E34.5 Androgen resistance syndrome
0.000 0.846 0.154
E34.4 Constitutional tall stature
0.000 0.846 0.154
E34.3 Short stature, not elsewhere classified
0.000 0.846 0.154
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.846 0.154
E34.1 Other hypersecretion of intestinal hormones
0.000 0.846 0.154
E25.9 Adrenogenital disorder, unspecified
0.000 0.849 0.151
E25.8 Other adrenogenital disorders
0.000 0.849 0.151
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.849 0.151
E30.9 Disorder of puberty, unspecified
0.000 0.849 0.151
E30.8 Other disorders of puberty
0.000 0.849 0.151
E30.1 Precocious puberty
0.000 0.849 0.151
E30.0 Delayed puberty
0.000 0.849 0.151
E31.9 Polyglandular dysfunction, unspecified
0.000 0.849 0.151
E31.8 Other polyglandular dysfunction
0.000 0.849 0.151
E31.1 Polyglandular hyperfunction
0.000 0.849 0.151
E31.0 Autoimmune polyglandular failure
0.000 0.849 0.151
E32.9 Disease of thymus, unspecified
0.000 0.849 0.151
E32.8 Other diseases of thymus
0.000 0.849 0.151
E32.1 Abscess of thymus
0.000 0.849 0.151
E32.0 Persistent hyperplasia of thymus
0.000 0.849 0.151
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.849 0.151
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.849 0.151
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.849 0.151
E06.5 Other chronic thyroiditis
0.000 0.849 0.151
E24.8 Other Cushing's syndrome
0.000 0.849 0.150
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.849 0.150
E24.3 Ectopic ACTH syndrome
0.000 0.849 0.150
E24.2 Drug-induced Cushing's syndrome
0.000 0.849 0.150
E24.1 Nelson's syndrome
0.000 0.849 0.150
E06.9 Thyroiditis, unspecified
0.000 0.849 0.150
E23.6 Other disorders of pituitary gland
0.000 0.855 0.145
I11 Hypertensive heart disease
0.000 0.856 0.144
E14.8 With unspecified complications
0.000 0.857 0.143
E28.3 Primary ovarian failure
0.000 0.858 0.142
E24.9 Cushing's syndrome, unspecified
0.000 0.859 0.141
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.859 0.141
E23.1 Drug-induced hypopituitarism
0.000 0.859 0.141
E14.5 With peripheral circulatory complications
0.000 0.861 0.139
E26.9 Hyperaldosteronism, unspecified
0.000 0.861 0.139
E26.8 Other hyperaldosteronism
0.000 0.861 0.139
E26.1 Secondary hyperaldosteronism
0.000 0.861 0.139
E14.7 With multiple complications
0.000 0.861 0.139
E14.0 With coma
0.000 0.861 0.139
E27 Other disorders of adrenal gland
0.000 0.861 0.138
E28.9 Ovarian dysfunction, unspecified
0.000 0.862 0.138
E28.8 Other ovarian dysfunction
0.000 0.862 0.138
E28.1 Androgen excess
0.000 0.862 0.138
E28.0 Oestrogen excess
0.000 0.862 0.138
E20.8 Other hypoparathyroidism
0.000 0.863 0.136
E20.1 Pseudohypoparathyroidism
0.000 0.863 0.136
E20.0 Idiopathic hypoparathyroidism
0.000 0.863 0.136
E04 Other non-toxic goitre
0.000 0.864 0.136
E50-E64 Other nutritional deficiencies
0.001 0.866 0.134
I13 Hypertensive heart and renal disease
0.000 0.866 0.134
K90.8 Other intestinal malabsorption
0.000 0.867 0.133
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.867 0.132
E23.0 Hypopituitarism
0.000 0.872 0.128
I12 Hypertensive renal disease
0.000 0.876 0.124
E14.2 Withrenal complications
0.000 0.876 0.124
E14.1 With ketoacidosis
0.000 0.876 0.124
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.877 0.123
E26.0 Primary hyperaldosteronism
0.000 0.878 0.122
E34.0 Carcinoid syndrome
0.000 0.880 0.119
I15 Secondary hypertension
0.000 0.884 0.116
E20.9 Hypoparathyroidism, unspecified
0.000 0.884 0.115
E28.2 Polycystic ovarian syndrome
0.000 0.887 0.113
E14.6 With other specified complications
0.000 0.892 0.107
K90.9 Intestinal malabsorption, unspecified
0.000 0.894 0.105
E23.2 Diabetes insipidus
0.000 0.895 0.105
E27.8 Other specified disorders of adrenal gland
0.000 0.897 0.103
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.898 0.102
I12.9 Hypertensive renal disease without renal failure
0.000 0.898 0.102
E27.5 Adrenomedullary hyperfunction
0.000 0.900 0.099
E27.0 Other adrenocortical overactivity
0.000 0.900 0.099
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.901 0.099
E04.8 Other specified non-toxic goitre
0.000 0.902 0.098
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.903 0.096
E63 Other nutritional deficiencies
0.001 0.903 0.096
E56 Other vitamin deficiencies
0.001 0.903 0.096
E51 Thiamine deficiency
0.001 0.903 0.096
E50 Vitamin A deficiency
0.001 0.903 0.096
E60 Dietary zinc deficiency
0.001 0.903 0.096
E59 Dietary selenium deficiency
0.001 0.903 0.096
E54 Ascorbic acid deficiency
0.001 0.903 0.096
E52 Niacin deficiency [pellagra]
0.001 0.903 0.096
E04.9 Non-toxic goitre, unspecified
0.000 0.903 0.097
E27.9 Disorder of adrenal gland, unspecified
0.000 0.903 0.096
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.904 0.096
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.904 0.096
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.904 0.096
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.904 0.096
E61 Deficiency of other nutrient elements
0.001 0.906 0.094
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.907 0.093
E58 Dietary calcium deficiency
0.001 0.908 0.092
E04.0 Non-toxic diffuse goitre
0.000 0.910 0.090
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.914 0.086
I15.8 Other secondary hypertension
0.000 0.917 0.083
I15.2 Hypertension secondary to endocrine disorders
0.000 0.917 0.083
I15.0 Renovascular hypertension
0.000 0.917 0.083
I15.9 Seconday hypertension, unspecified
0.000 0.919 0.081
E27.1 Primary adrenocortical insufficiency
0.000 0.919 0.081
E04.1 Non-toxic single thyroid nodule
0.000 0.921 0.079
E07.9 Disorder of thyroid, unspecified
0.000 0.922 0.078
E61.1 Iron deficiency
0.000 0.922 0.078
E50.9 Vitamin A deficiency, unspecified
0.001 0.930 0.069
E50.8 Other manifestations of vitamin A deficiency
0.001 0.930 0.069
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.930 0.069
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.930 0.069
E50.5 Vitamin A deficiency with night blindness
0.001 0.930 0.069
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.930 0.069
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.930 0.069
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.930 0.069
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.930 0.069
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.930 0.069
E51.9 Thiamine deficiency, unspecified
0.001 0.930 0.069
E51.8 Other manifestations of thiamine deficiency
0.001 0.930 0.069
E51.2 Wernicke's encephalopathy
0.001 0.930 0.069
E51.1 Beriberi
0.001 0.930 0.069
E56.9 Vitamin deficiency, unspecified
0.001 0.930 0.069
E56.8 Deficiency of other vitamins
0.001 0.930 0.069
E56.1 Deficiency of vitamin K
0.001 0.930 0.069
E56.0 Deficiency of vitamin E
0.001 0.930 0.069
E63.9 Nutritional deficiency, unspecified
0.001 0.930 0.069
E63.8 Other specified nutritional deficiencies
0.001 0.930 0.069
E63.1 Imbalance of constituents of food intake
0.001 0.930 0.069
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.930 0.069
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.930 0.069
E64.8 Sequelae of other nutritional deficiencies
0.001 0.930 0.069
E64.3 Sequelae of rickets
0.001 0.930 0.069
E64.2 Sequelae of vitamin C deficiency
0.001 0.930 0.069
E64.1 Sequelae of vitamin A deficiency
0.001 0.930 0.069
E64.0 Sequelae of protein-energy malnutrition
0.001 0.930 0.069
I15.1 Hypertension secondary to other renal disorders
0.000 0.931 0.068
E27.2 Addisonian crisis
0.000 0.932 0.067
E61.9 Deficiency of nutrient element, unspecified
0.001 0.932 0.067
E61.8 Deficiency of other specified nutrient elements
0.001 0.932 0.067
E61.7 Deficiency of multiple nutrient elements
0.001 0.932 0.067
E61.6 Vanadium deficiency
0.001 0.932 0.067
E61.5 Molybdenum deficiency
0.001 0.932 0.067
E61.4 Chromium deficiency
0.001 0.932 0.067
E61.3 Manganese deficiency
0.001 0.932 0.067
E61.0 Copper deficiency
0.001 0.932 0.067
E55 Vitamin D deficiency
0.001 0.939 0.060
E66.8 Other obesity
0.000 0.939 0.061
I12.0 Hypertensive renal disease with renal failure
0.000 0.945 0.055
E11.4 With neurological complications
0.000 0.947 0.053
E53 Deficiency of other B group vitamins
0.001 0.949 0.050
E61.2 Magnesium deficiency
0.001 0.953 0.046
E55.0 Rickets, active
0.001 0.956 0.043
E83 Disorders of mineral metabolism
0.039 0.960 0.001
E53.1 Pyridoxine deficiency
0.001 0.963 0.036
E53.0 Riboflavin deficiency
0.001 0.963 0.036
E83.9 Disorder of mineral metabolism, unspecified
0.032 0.967 0.001
E04.2 Non-toxic multinodular goitre
0.000 0.968 0.032
E83.8 Other disorders of mineral metabolism
0.028 0.971 0.001
E83.2 Disorders of zinc metabolism
0.028 0.971 0.001
E83.0 Disorders of copper metabolism
0.028 0.971 0.001
E53.9 Vitamin B deficiency, unspecified
0.001 0.974 0.026
E83.3 Disorders of phosphorus metabolism
0.017 0.982 0.001
F33.9 Recurrent depressive disorder, unspecified
0.016 0.984 0.000
E53.8 Deficiency of other specified B group vitamins
0.000 0.984 0.016
I84.1 Internal haemorrhoids with other complications
0.000 0.986 0.014
K90-K93 Other diseases of the digestive system
0.000 0.986 0.013
M25.84 Other specified joint disorders (Hand)
0.000 0.987 0.013
E83.4 Disorders of magnesium metabolism
0.012 0.987 0.001
E83.5 Disorders of calcium metabolism
0.011 0.989 0.000
C83.3 Large cell (diffuse)
0.000 0.989 0.011
M25.8 Other specified joint disorders
0.000 0.989 0.011
F33 Recurrent depressive disorder
0.011 0.989 0.000
K60.2 Anal fissure, unspecified
0.000 0.989 0.011
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.000 0.990 0.010
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.990 0.010
M25.83 Other specified joint disorders (Forearm)
0.000 0.990 0.010
E55.9 Vitamin D deficiency, unspecified
0.002 0.991 0.007
M25.81 Other specified joint disorders (Shoulder region)
0.000 0.991 0.009
E14.9 Without complications
0.000 0.991 0.009
D25.1 Intramural leiomyoma of uterus
0.000 0.991 0.009
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.009 0.991 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.008 0.991 0.000
M25.86 Other specified joint disorders (Lower leg)
0.000 0.992 0.008
F33.0 Recurrent depressive disorder, current episode mild
0.008 0.992 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.008 0.992 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.000 0.992 0.008
M25.82 Other specified joint disorders (Upper arm)
0.000 0.992 0.008
M25.80 Other specified joint disorders (Multiple sites)
0.000 0.992 0.008
F33.8 Other recurrent depressive disorders
0.008 0.992 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.008 0.992 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.993 0.007
K93.1 Megacolon in Chagas' disease
0.000 0.993 0.007
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.993 0.007
M65.34 Trigger finger-Hand
0.007 0.993 0.000
N18.0 End-stage renal disease
0.000 0.993 0.007
M25.88 Other specified joint disorders (Other)
0.000 0.994 0.006
F32.3 Severe depressive episode with psychotic symptoms
0.006 0.994 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.000 0.994 0.006
S52.00 Fracture of upper end of ulna (closed)
0.006 0.994 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.000 0.994 0.006
T83.0 Mechanical complication of urinary (indwelling) catheter
0.006 0.994 0.000
H00 Hordeolum and chalazion
0.006 0.994 0.000
H00.1 Chalazion
0.006 0.994 0.000
F30-F39 Mood [affective] disorders
0.006 0.994 0.000
D04.7 Skin of lower limb, including hip
0.000 0.994 0.006
N18.5 Chronic kidney disease, stage 5
0.000 0.995 0.005
N39.8 Other specified disorders of urinary system
0.005 0.995 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.005 0.995 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.005 0.995 0.000
F32 Depressive episode
0.005 0.995 0.000
N18 Chronic renal failure
0.000 0.995 0.005
I21.4 Acute subendocardial myocardial infarction
0.000 0.995 0.005
R40.2 Coma, unspecified
0.000 0.995 0.005
T43.2 Other and unspecified antidepressants
0.005 0.995 0.000
Z04.1 Examination and observation following transport accident
0.005 0.995 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.005 0.995 0.000
F39 Unspecified mood [affective] disorder
0.004 0.995 0.000
N88.2 Stricture and stenosis of cervix uteri
0.000 0.995 0.005
N18.2 Chronic kidney disease, stage 2
0.000 0.996 0.004
L89.3 Stage IV decubitus ulcer
0.004 0.996 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.004 0.996 0.000
S62.60 Fracture of other finger (closed)
0.004 0.996 0.000
F38 Other mood [affective] disorders
0.004 0.996 0.000
K83.8 Other specified diseases of biliary tract
0.004 0.996 0.000
N18.9 Chronic renal failure, unspecified
0.000 0.996 0.004
R52.1 Chronic intractable pain
0.004 0.996 0.000
F30 Manic episode
0.004 0.996 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.004 0.996 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.004 0.996 0.000
F31 Bipolar affective disorder
0.004 0.996 0.000
F32.0 Mild depressive episode
0.004 0.996 0.000
L89 Decubitus ulcer
0.004 0.996 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.004 0.996 0.000
N18.8 Other chronic renal failure
0.000 0.996 0.004
D04 Carcinoma in situ of skin
0.000 0.996 0.004
F32.8 Other depressive episodes
0.004 0.996 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.004 0.996 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.004 0.996 0.000
E70-E90 Metabolic disorders
0.000 0.996 0.003
F32.2 Severe depressive episode without psychotic symptoms
0.004 0.996 0.000
F34 Persistent mood [affective] disorders
0.004 0.996 0.000
F32.1 Moderate depressive episode
0.004 0.996 0.000
N42.9 Disorder of prostate, unspecified
0.000 0.996 0.004
E80.4 Gilbert's syndrome
0.000 0.996 0.004
R40 Somnolence, stupor and coma
0.000 0.996 0.004
R40.0 Somnolence
0.000 0.996 0.004
H35.6 Retinal haemorrhage
0.000 0.996 0.004
M65.3 Trigger finger
0.003 0.996 0.000
S62.70 Multiple fractures of fingers (closed)
0.004 0.996 0.000
F31.7 Bipolar affective disorder, currently in remission
0.003 0.996 0.000
N18.1 Chronic kidney disease, stage 1
0.000 0.996 0.003
Z71.8 Other specified counselling
0.004 0.996 0.000
F30.1 Mania without psychotic symptoms
0.003 0.997 0.000
L89.2 Stage III decubitus ulcer
0.003 0.997 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.997 0.003
D04.4 Skin of scalp and neck
0.000 0.997 0.003
S62.6 Fracture of other finger
0.003 0.997 0.000
F30.9 Manic episode, unspecified
0.003 0.997 0.000
F38.8 Other specified mood [affective] disorders
0.003 0.997 0.000
F38.1 Other recurrent mood [affective] disorders
0.003 0.997 0.000
F38.0 Other single mood [affective] disorders
0.003 0.997 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.003 0.997 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.003 0.997 0.000
R40.1 Stupor
0.000 0.997 0.003
F31.9 Bipolar affective disorder, unspecified
0.003 0.997 0.000
D04.6 Skin of upper limb, including shoulder
0.000 0.997 0.003
F30.8 Other manic episodes
0.003 0.997 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.003 0.997 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.003 0.997 0.000
F30.2 Mania with psychotic symptoms
0.003 0.997 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.003 0.997 0.000
S62.61 Fracture of other finger (open)
0.003 0.997 0.000
D04.3 Skin of other and unspecified parts of face
0.000 0.997 0.003
F31.8 Other bipolar affective disorders
0.003 0.997 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.003 0.997 0.000
D04.2 Skin of ear and external auricular canal
0.000 0.997 0.003
D04.9 Skin, unspecified
0.000 0.997 0.003
H66.9 Otitis media, unspecified
0.003 0.997 0.000
D04.8 Skin of other sites
0.000 0.997 0.003
D04.0 Skin of lip
0.000 0.997 0.003
E84 Cystic fibrosis
0.000 0.997 0.003
E77 Disorders of glycoprotein metabolism
0.000 0.997 0.003
E76 Disorders of glycosaminoglycan metabolism
0.000 0.997 0.003
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.997 0.003
E70 Disorders of aromatic amino-acid metabolism
0.000 0.997 0.003
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.997 0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.003 0.997 0.000
F34.9 Persistent mood [affective] disorder, unspecified
0.003 0.997 0.000
F34.8 Other persistent mood [affective] disorders
0.003 0.997 0.000
F34.0 Cyclothymia
0.003 0.997 0.000
T83.2 Mechanical complication of graft of urinary organ
0.003 0.997 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.997 0.002
E72 Other disorders of amino-acid metabolism
0.000 0.997 0.002
M65.39 Trigger finger-Site unspec
0.003 0.997 0.000
M65.38 Trigger finger-Other
0.003 0.997 0.000
M65.37 Trigger finger-Ankle/foot
0.003 0.997 0.000
M65.36 Trigger finger-Lower leg
0.003 0.997 0.000
M65.35 Trigger finger-Pelvic/thigh
0.003 0.997 0.000
M65.33 Trigger finger-Forearm
0.003 0.997 0.000
M65.32 Trigger finger-Upper arm
0.003 0.997 0.000
M65.31 Trigger finger-Shldr region
0.003 0.997 0.000
M65.30 Trigger finger-Mult sites
0.003 0.997 0.000
D04.5 Skin of trunk
0.000 0.997 0.003
F31.6 Bipolar affective disorder, current episode mixed
0.003 0.997 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.997 0.002
F30.0 Hypomania
0.003 0.997 0.000
M95.0 Acquired deformity of nose
0.003 0.997 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.003 0.997 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.003 0.997 0.000
D04.1 Skin of eyelid, including canthus
0.000 0.997 0.003
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.997 0.002
E80.5 Crigler-Najjar syndrome
0.000 0.997 0.002
E80.3 Defects of catalase and peroxydase
0.000 0.997 0.002
E80.0 Hereditary erythropoietic porphyria
0.000 0.997 0.002
T43.5 Other and unspecified antipsychotics and neuroleptics
0.003 0.997 0.000
R07.0 Pain in throat
0.003 0.997 0.000
E85 Amyloidosis
0.000 0.997 0.002
F31.0 Bipolar affective disorder, current episode hypomanic
0.003 0.997 0.000
S62.7 Multiple fractures of fingers
0.003 0.997 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.997 0.003
N18.4 Chronic kidney disease, stage 4
0.000 0.997 0.003
R25.3 Fasciculation
0.003 0.997 0.000
E80.1 Porphyria cutanea tarda
0.000 0.997 0.002
N18.3 Chronic kidney disease, stage 3
0.000 0.997 0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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