TreeWAS – Variant ID: rs415890

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.000	1.000
E00-E07 Disorders of thyroid gland	0.000	0.001	0.999
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.002	0.998
E05.9 Thyrotoxicosis, unspecified	0.000	0.003	0.997
E03.8 Other specified hypothyroidism	0.000	0.066	0.934
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.070	0.930
E07 Other disorders of thyroid	0.000	0.146	0.854
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.163	0.837
E03.1 Congenital hypothyroidism without goitre	0.000	0.211	0.789
E07.9 Disorder of thyroid, unspecified	0.000	0.224	0.776
E05.5 Thyroid crisis or storm	0.000	0.283	0.717
E05.4 Thyrotoxicosis factitia	0.000	0.283	0.717
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.283	0.717
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.283	0.717
E03.5 Myxoedema coma	0.000	0.283	0.717
E03.4 Atrophy of thyroid (acquired)	0.000	0.283	0.717
E03.3 Postinfectious hypothyroidism	0.000	0.283	0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.283	0.716
E00 Congenital iodine-deficiency syndrome	0.000	0.283	0.716
C44.3 Skin of other and unspecified parts of face	0.712	0.288	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.309	0.691
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.378	0.622
E07.1 Dyshormogenetic goitre	0.000	0.388	0.612
E07.0 Hypersecretion of calcitonin	0.000	0.388	0.612
C44.5 Skin of trunk	0.601	0.399	0.000
E05.8 Other thyrotoxicosis	0.000	0.401	0.599
C44 Other malignant neoplasms of skin	0.598	0.402	0.000
C44.6 Skin of upper limb, including shoulder	0.564	0.436	0.000
E07.8 Other specified disorders of thyroid	0.000	0.470	0.529
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.486	0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.486	0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.486	0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.486	0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.486	0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.486	0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.486	0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.486	0.514
E06 Thyroiditis	0.000	0.527	0.472
C44.2 Skin of ear and external auricular canal	0.459	0.541	0.000
C44.8 Overlapping lesion of skin	0.429	0.571	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.393	0.607	0.000
E06.5 Other chronic thyroiditis	0.000	0.627	0.372
E06.4 Drug-induced thyroiditis	0.000	0.661	0.339
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.661	0.339
E06.0 Acute thyroiditis	0.000	0.661	0.339
E06.1 Subacute thyroiditis	0.000	0.675	0.325
E06.3 Autoimmune thyroiditis	0.000	0.745	0.254
C43-C44 Melanoma and other malignant neoplasms of skin	0.242	0.758	0.000
E04 Other non-toxic goitre	0.000	0.787	0.213
E06.9 Thyroiditis, unspecified	0.001	0.807	0.193
C43 Malignant melanoma of skin	0.169	0.831	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.837	0.163
C43.5 Malignant melanoma of trunk	0.162	0.838	0.000
E04.8 Other specified non-toxic goitre	0.000	0.847	0.153
L43.9 Lichen planus, unspecified	0.000	0.849	0.151
C43.4 Malignant melanoma of scalp and neck	0.143	0.857	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.138	0.862	0.000
C44.0 Skin of lip	0.129	0.871	0.000
C43.9 Malignant melanoma of skin, unspecified	0.123	0.877	0.000
C43.8 Overlapping malignant melanoma of skin	0.121	0.878	0.000
C43.0 Malignant melanoma of lip	0.121	0.878	0.000
C44.4 Skin of scalp and neck	0.120	0.880	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.118	0.882	0.000
C44.7 Skin of lower limb, including hip	0.107	0.893	0.000
K50.9 Crohn's disease, unspecified	0.000	0.910	0.090
K50 Crohn's disease [regional enteritis]	0.000	0.911	0.089
K50.0 Crohn's disease of small intestine	0.000	0.912	0.088
E04.2 Non-toxic multinodular goitre	0.000	0.916	0.084
C43.2 Malignant melanoma of ear and external auricular canal	0.079	0.920	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.921	0.079
K50.1 Crohn's disease of large intestine	0.000	0.923	0.077
K50.8 Other Crohn's disease	0.000	0.927	0.073
E04.9 Non-toxic goitre, unspecified	0.000	0.930	0.070
L43 Lichen planus	0.000	0.940	0.060
C44.1 Skin of eyelid, including canthus	0.048	0.952	0.000
L43.3 Subacute (active) lichen planus	0.000	0.957	0.043
L43.2 Lichenoid drug reaction	0.000	0.957	0.043
L43.1 Bullous lichen planus	0.000	0.957	0.043
L43.8 Other lichen planus	0.000	0.958	0.042
L43.0 Hypertrophic lichen planus	0.000	0.960	0.040
K50-K52 Noninfective enteritis and colitis	0.000	0.961	0.039
K51 Ulcerative colitis	0.000	0.964	0.036
C43.6 Malignant melanoma of upper limb, including shoulder	0.035	0.965	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.966	0.034
K51.5 Mucosal proctocolitis	0.000	0.966	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.968	0.032
K51.8 Other ulcerative colitis	0.000	0.971	0.029
E50-E64 Other nutritional deficiencies	0.000	0.973	0.026
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.974	0.026
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.974	0.026
E53 Deficiency of other B group vitamins	0.000	0.975	0.025
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.975	0.025
E53.8 Deficiency of other specified B group vitamins	0.000	0.975	0.025
E58 Dietary calcium deficiency	0.000	0.978	0.022
E16 Other disorders of pancreatic internal secretion	0.000	0.979	0.021
K51.4 Pseudopolyposis of colon	0.000	0.979	0.021
E40-E46 Malnutrition	0.000	0.979	0.020
E51 Thiamine deficiency	0.000	0.980	0.020
E16.2 Hypoglycaemia, unspecified	0.000	0.980	0.020
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.981	0.019
E63 Other nutritional deficiencies	0.000	0.981	0.019
E50 Vitamin A deficiency	0.000	0.981	0.019
E60 Dietary zinc deficiency	0.000	0.981	0.019
E59 Dietary selenium deficiency	0.000	0.981	0.019
E52 Niacin deficiency [pellagra]	0.000	0.981	0.019
E15 Nondiabetic hypoglycaemic coma	0.000	0.981	0.019
E54 Ascorbic acid deficiency	0.000	0.981	0.018
E53.1 Pyridoxine deficiency	0.000	0.982	0.018
E53.0 Riboflavin deficiency	0.000	0.982	0.018
E56 Other vitamin deficiencies	0.000	0.982	0.017
E53.9 Vitamin B deficiency, unspecified	0.000	0.983	0.016
E61 Deficiency of other nutrient elements	0.000	0.984	0.016
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.984	0.015
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.984	0.015
E16.4 Abnormal secretion of gastrin	0.000	0.984	0.015
E16.3 Increased secretion of glucagon	0.000	0.984	0.015
E51.2 Wernicke's encephalopathy	0.000	0.985	0.015
K51.9 Ulcerative colitis, unspecified	0.000	0.985	0.015
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.985	0.015
E45 Retarded development following protein-energy malnutrition	0.000	0.985	0.015
E43 Unspecified severe protein-energy malnutrition	0.000	0.985	0.015
E42 Marasmic kwashiorkor	0.000	0.985	0.015
E41 Nutritional marasmus	0.000	0.985	0.015
E40 Kwashiorkor	0.000	0.985	0.015
E51.9 Thiamine deficiency, unspecified	0.000	0.985	0.014
E51.8 Other manifestations of thiamine deficiency	0.000	0.985	0.014
E51.1 Beriberi	0.000	0.985	0.014
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.986	0.014
E50.9 Vitamin A deficiency, unspecified	0.000	0.986	0.014
E50.8 Other manifestations of vitamin A deficiency	0.000	0.986	0.014
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.986	0.014
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.986	0.014
E50.5 Vitamin A deficiency with night blindness	0.000	0.986	0.014
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.986	0.014
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.986	0.014
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.986	0.014
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.986	0.014
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.986	0.014
E63.9 Nutritional deficiency, unspecified	0.000	0.986	0.014
E63.8 Other specified nutritional deficiencies	0.000	0.986	0.014
E63.1 Imbalance of constituents of food intake	0.000	0.986	0.014
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.986	0.014
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.986	0.014
E64.8 Sequelae of other nutritional deficiencies	0.000	0.986	0.014
E64.3 Sequelae of rickets	0.000	0.986	0.014
E64.2 Sequelae of vitamin C deficiency	0.000	0.986	0.014
E64.1 Sequelae of vitamin A deficiency	0.000	0.986	0.014
E64.0 Sequelae of protein-energy malnutrition	0.000	0.986	0.014
H54.0 Blindness, both eyes	0.013	0.987	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.987	0.013
E56.9 Vitamin deficiency, unspecified	0.000	0.987	0.013
E56.8 Deficiency of other vitamins	0.000	0.987	0.013
E56.0 Deficiency of vitamin E	0.000	0.987	0.013
E16.1 Other hypoglycaemia	0.000	0.987	0.012
E46 Unspecified protein-energy malnutrition	0.000	0.988	0.012
E55 Vitamin D deficiency	0.001	0.988	0.012
E10-E14 Diabetes mellitus	0.000	0.988	0.012
E61.9 Deficiency of nutrient element, unspecified	0.000	0.988	0.012
E61.8 Deficiency of other specified nutrient elements	0.000	0.988	0.012
E61.7 Deficiency of multiple nutrient elements	0.000	0.988	0.012
E61.6 Vanadium deficiency	0.000	0.988	0.012
E61.5 Molybdenum deficiency	0.000	0.988	0.012
E61.4 Chromium deficiency	0.000	0.988	0.012
E61.3 Manganese deficiency	0.000	0.988	0.012
E61.0 Copper deficiency	0.000	0.988	0.012
E61.2 Magnesium deficiency	0.000	0.988	0.011
E14 Unspecified diabetes mellitus	0.000	0.989	0.011
E56.1 Deficiency of vitamin K	0.000	0.989	0.011
E44.1 Mild protein-energy malnutrition	0.000	0.989	0.011
E44.0 Moderate protein-energy malnutrition	0.000	0.989	0.011
E65-E68 Obesity and other hyperalimentation	0.000	0.989	0.010
C43.7 Malignant melanoma of lower limb, including hip	0.009	0.990	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.990	0.010
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.991	0.009
O47.1 False labour at or after 37 completed weeks of gestation	0.009	0.991	0.000
E14.4 With neurological complications	0.000	0.991	0.009
E70-E90 Metabolic disorders	0.000	0.991	0.009
E14.9 Without complications	0.000	0.991	0.009
E89.2 Postprocedural hypoparathyroidism	0.000	0.991	0.009
E55.0 Rickets, active	0.001	0.991	0.009
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.991	0.009
E14.1 With ketoacidosis	0.000	0.991	0.009
E12 Malnutrition-related diabetes mellitus	0.000	0.991	0.009
E14.3 With ophthalmic complications	0.000	0.991	0.009
E83 Disorders of mineral metabolism	0.000	0.991	0.009
E61.1 Iron deficiency	0.000	0.991	0.009
O47.0 False labour before 37 completed weeks of gestation	0.009	0.991	0.000
E23.0 Hypopituitarism	0.000	0.991	0.009
E14.5 With peripheral circulatory complications	0.000	0.991	0.009
E14.8 With unspecified complications	0.000	0.991	0.009
E14.2 Withrenal complications	0.000	0.992	0.008
E83.3 Disorders of phosphorus metabolism	0.000	0.992	0.008
E14.7 With multiple complications	0.000	0.992	0.008
E14.0 With coma	0.000	0.992	0.008
E83.1 Disorders of iron metabolism	0.000	0.992	0.008
O47 False labour	0.008	0.992	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.992	0.008
E13 Other specified diabetes mellitus	0.000	0.992	0.008
E14.6 With other specified complications	0.000	0.992	0.008
E67 Other hyperalimentation	0.000	0.992	0.008
E68 Sequelae of hyperalimentation	0.000	0.992	0.008
E20-E35 Disorders of other endocrine glands	0.000	0.992	0.008
C53.9 Cervix uteri, unspecified	0.000	0.992	0.008
E23 Hypofunction and other disorders of pituitary gland	0.000	0.992	0.008
K52.1 Toxic gastro-enteritis and colitis	0.000	0.992	0.008
L40-L45 Papulosquamous disorders	0.000	0.992	0.007
E79 Disorders of purine and pyrimidine metabolism	0.000	0.993	0.007
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.993	0.007
E72 Other disorders of amino-acid metabolism	0.000	0.993	0.007
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.993	0.007
E89.1 Postprocedural hypoinsulinaemia	0.000	0.993	0.007
S83.2 Tear of meniscus, current	0.000	0.993	0.007
E88 Other metabolic disorders	0.000	0.993	0.007
E74 Other disorders of carbohydrate metabolism	0.000	0.993	0.007
E77 Disorders of glycoprotein metabolism	0.000	0.993	0.007
E76 Disorders of glycosaminoglycan metabolism	0.000	0.993	0.007
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.993	0.007
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.993	0.007
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.993	0.007
E89.5 Postprocedural testicular hypofunction	0.000	0.993	0.007
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.993	0.007
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
E73 Lactose intolerance	0.000	0.993	0.007
E12.9 Without complications	0.000	0.993	0.006
E12.8 With unspecified complications	0.000	0.993	0.006
E12.7 With multiple complications	0.000	0.993	0.006
E12.6 With other specified complications	0.000	0.993	0.006
E12.5 With peripheral circulatory complications	0.000	0.993	0.006
E12.4 With neurological complications	0.000	0.993	0.006
E12.3 With ophthalmic complications	0.000	0.993	0.006
E12.2 With renal complications	0.000	0.993	0.006
E12.1 With ketoacidosis	0.000	0.993	0.006
E12.0 With coma	0.000	0.993	0.006
E70 Disorders of aromatic amino-acid metabolism	0.000	0.993	0.007
O47.9 False labour, unspecified	0.007	0.993	0.000
H33.2 Serous retinal detachment	0.000	0.993	0.007
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.993	0.006
E83.8 Other disorders of mineral metabolism	0.000	0.993	0.006
E83.2 Disorders of zinc metabolism	0.000	0.993	0.006
E83.0 Disorders of copper metabolism	0.000	0.993	0.006
E84 Cystic fibrosis	0.000	0.994	0.006
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.994	0.006
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.994	0.006
E23.7 Disorder of pituitary gland, unspecified	0.000	0.994	0.006
E26 Hyperaldosteronism	0.000	0.994	0.006
E85 Amyloidosis	0.000	0.994	0.006
E13.8 With unspecified complications	0.000	0.994	0.006
E13.7 With multiple complications	0.000	0.994	0.006
E13.6 With other specified complications	0.000	0.994	0.006
E13.5 With peripheral circulatory complications	0.000	0.994	0.006
E13.4 With neurological complications	0.000	0.994	0.006
E13.2 With renal complications	0.000	0.994	0.006
E13.1 With ketoacidosis	0.000	0.994	0.006
E13.0 With coma	0.000	0.994	0.006
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.994	0.006
E31 Polyglandular dysfunction	0.000	0.994	0.006
E13.3 With ophthalmic complications	0.000	0.994	0.006
E25 Adrenogenital disorders	0.000	0.994	0.006
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.994	0.006
E67.8 Other specified hyperalimentation	0.000	0.994	0.006
E67.3 Hypervitaminosis D	0.000	0.994	0.006
E67.2 Megavitamin-B6 syndrome	0.000	0.994	0.006
E67.1 Hypercarotenaemia	0.000	0.994	0.006
E67.0 Hypervitaminosis A	0.000	0.994	0.006
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E32 Diseases of thymus	0.000	0.994	0.006
E30 Disorders of puberty, not elsewhere classified	0.000	0.994	0.006
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
E88.2 Lipomatosis, not elsewhere classified	0.000	0.994	0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.994	0.006
E23.1 Drug-induced hypopituitarism	0.000	0.994	0.006
E89.3 Postprocedural hypopituitarism	0.000	0.994	0.006
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.994	0.006
L41 Parapsoriasis	0.000	0.994	0.006
E24 Cushing's syndrome	0.000	0.994	0.006
L44 Other papulosquamous disorders	0.000	0.994	0.005
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.994	0.005
E89.4 Postprocedural ovarian failure	0.000	0.994	0.005
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.994	0.005
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.994	0.006
E72.0 Disorders of amino-acid transport	0.000	0.994	0.005
Z88.5 Personal history of allergy to narcotic agent	0.006	0.994	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.994	0.005
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.994	0.005
E79.1 Lesch-Nyhan syndrome	0.000	0.994	0.005
N30.1 Interstitial cystitis (chronic)	0.006	0.994	0.000
E88.8 Other specified metabolic disorders	0.000	0.995	0.005
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.995	0.005
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.995	0.005
E72.5 Disorders of glycine metabolism	0.000	0.995	0.005
E72.4 Disorders of ornithine metabolism	0.000	0.995	0.005
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.995	0.005
E72.2 Disorders of urea cycle metabolism	0.000	0.995	0.005
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.995	0.005
E88.9 Metabolic disorder, unspecified	0.000	0.995	0.005
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.995	0.005
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.995	0.005
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.995	0.005
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.995	0.005
E74.2 Disorders of galactose metabolism	0.000	0.995	0.005
E74.1 Disorders of fructose metabolism	0.000	0.995	0.005
E74.0 Glycogen storage disease	0.000	0.995	0.005
E13.9 Without complications	0.000	0.995	0.005
E71.3 Disorders of fatty-acid metabolism	0.000	0.995	0.005
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.995	0.005
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.995	0.005
E71.0 Maple-syrup-urine disease	0.000	0.995	0.005
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.995	0.005
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.995	0.005
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.995	0.005
E76.2 Other mucopolysaccharidoses	0.000	0.995	0.005
E76.1 Mucopolysaccharidosis, type II	0.000	0.995	0.005
E76.0 Mucopolysaccharidosis, type I	0.000	0.995	0.005
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.995	0.005
E77.8 Other disorders of glycoprotein metabolism	0.000	0.995	0.005
E77.1 Defects in glycoprotein degradation	0.000	0.995	0.005
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.995	0.005
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
E28 Ovarian dysfunction	0.000	0.995	0.005
E88.3 Tumour lysis syndrome	0.000	0.995	0.005
E26.9 Hyperaldosteronism, unspecified	0.000	0.995	0.005
E73.8 Other lactose intolerance	0.000	0.995	0.005
E73.1 Secondary lactase deficiency	0.000	0.995	0.005
E73.0 Congenital lactase deficiency	0.000	0.995	0.005
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.995	0.005
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.995	0.005
E70.2 Disorders of tyrosine metabolism	0.000	0.995	0.005
E70.1 Other hyperphenylalaninaemias	0.000	0.995	0.005
E70.0 Classical phenylketonuria	0.000	0.995	0.005
E22 Hyperfunction of pituitary gland	0.000	0.995	0.005
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.995	0.005
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.995	0.005
E23.2 Diabetes insipidus	0.000	0.995	0.005
E75.6 Lipid storage disorder, unspecified	0.000	0.995	0.005
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.995	0.005
E75.3 Sphingolipidosis, unspecified	0.000	0.995	0.005
E75.1 Other gangliosidosis	0.000	0.995	0.005
E75.0 GM2 gangliosidosis	0.000	0.995	0.005
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.000	0.995	0.005
E84.8 Cystic fibrosis with other manifestations	0.000	0.995	0.005
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.995	0.005
E75.5 Other lipid storage disorders	0.000	0.995	0.005
E73.9 Lactose intolerance, unspecified	0.000	0.995	0.005
E22.0 Acromegaly and pituitary gigantism	0.000	0.995	0.005
K52.3 Indeterminate colitis	0.000	0.995	0.005
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.995	0.005
E29 Testicular dysfunction	0.000	0.995	0.005
E70.3 Albinism	0.000	0.995	0.005
E75.2 Other sphingolipidosis	0.000	0.995	0.005
E85.8 Other amyloidosis	0.000	0.995	0.005
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
E31.0 Autoimmune polyglandular failure	0.000	0.995	0.005
T79.6 Traumatic ischaemia of muscle	0.000	0.995	0.005
E20 Hypoparathyroidism	0.000	0.995	0.004
E83.5 Disorders of calcium metabolism	0.000	0.995	0.005
E85.4 Organ-limited amyloidosis	0.000	0.995	0.005
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
M87.9 Osteonecrosis, unspecified	0.000	0.995	0.005
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.995	0.005
E26.8 Other hyperaldosteronism	0.000	0.995	0.004
E26.1 Secondary hyperaldosteronism	0.000	0.995	0.004
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.995	0.004
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.995	0.004
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.995	0.004
E28.3 Primary ovarian failure	0.000	0.995	0.005
E31.9 Polyglandular dysfunction, unspecified	0.000	0.995	0.004
E31.8 Other polyglandular dysfunction	0.000	0.995	0.004
E31.1 Polyglandular hyperfunction	0.000	0.995	0.004
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.995	0.004
E24.9 Cushing's syndrome, unspecified	0.000	0.995	0.004
E25.9 Adrenogenital disorder, unspecified	0.000	0.995	0.004
E25.8 Other adrenogenital disorders	0.000	0.995	0.004
E30.9 Disorder of puberty, unspecified	0.000	0.995	0.004
E30.8 Other disorders of puberty	0.000	0.995	0.004
E30.1 Precocious puberty	0.000	0.995	0.004
E30.0 Delayed puberty	0.000	0.995	0.004
E32.9 Disease of thymus, unspecified	0.000	0.995	0.004
E32.8 Other diseases of thymus	0.000	0.995	0.004
E32.1 Abscess of thymus	0.000	0.995	0.004
E32.0 Persistent hyperplasia of thymus	0.000	0.995	0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.995	0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.995	0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.995	0.004
S83.3 Tear of articular cartilage of knee, current	0.000	0.995	0.004
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.996	0.004
L41.1 Pityriasis lichenoides chronica	0.000	0.996	0.004
L41.9 Parapsoriasis, unspecified	0.000	0.996	0.004
L41.8 Other parapsoriasis	0.000	0.996	0.004
L41.5 Retiform parapsoriasis	0.000	0.996	0.004
L41.4 Large plaque parapsoriasis	0.000	0.996	0.004
L41.3 Small plaque parapsoriasis	0.000	0.996	0.004
L41.2 Lymphomatoid papulosis	0.000	0.996	0.004
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.996	0.004
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.996	0.004
E24.3 Ectopic ACTH syndrome	0.000	0.996	0.004
E24.1 Nelson's syndrome	0.000	0.996	0.004
E78.2 Mixed hyperlipidaemia	0.000	0.996	0.004
L44.9 Papulosquamous disorder, unspecified	0.000	0.996	0.004
L44.8 Other specified papulosquamous disorders	0.000	0.996	0.004
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.996	0.004
L44.3 Lichen ruber moniliformis	0.000	0.996	0.004
L44.2 Lichen striatus	0.000	0.996	0.004
L44.1 Lichen nitidus	0.000	0.996	0.004
L44.0 Pityriasis rubra pilaris	0.000	0.996	0.004
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.000	0.996	0.004
E24.0 Pituitary-dependent Cushing's disease	0.000	0.996	0.004
L42 Pityriasis rosea	0.000	0.996	0.004
E85.9 Amyloidosis, unspecified	0.000	0.996	0.004
M87.2 Osteonecrosis due to previous trauma	0.000	0.996	0.004
E24.8 Other Cushing's syndrome	0.000	0.996	0.004
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.996	0.004
E65 Localised adiposity	0.000	0.996	0.004
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.996	0.004
S83.7 Injury to multiple structures of knee	0.000	0.996	0.004
E24.2 Drug-induced Cushing's syndrome	0.000	0.996	0.004
E78.4 Other hyperlipidaemia	0.000	0.996	0.004
Z04.8 Examination and observation for other specified reasons	0.000	0.996	0.004
E23.6 Other disorders of pituitary gland	0.000	0.996	0.004
E28.9 Ovarian dysfunction, unspecified	0.000	0.996	0.004
E28.8 Other ovarian dysfunction	0.000	0.996	0.004
E28.1 Androgen excess	0.000	0.996	0.004
E28.0 Oestrogen excess	0.000	0.996	0.004
S83.1 Dislocation of knee	0.000	0.996	0.004
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.996	0.004
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.996	0.004
E22.8 Other hyperfunction of pituitary gland	0.000	0.996	0.004
M87 Osteonecrosis	0.000	0.996	0.004
E85.3 Secondary systemic amyloidosis	0.000	0.996	0.004
E21.2 Other hyperparathyroidism	0.000	0.996	0.004
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.996	0.004
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.996	0.004
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.004
E29.8 Other testicular dysfunction	0.000	0.996	0.004
E29.0 Testicular hyperfunction	0.000	0.996	0.004
E66 Obesity	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.004	0.996	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.004	0.996	0.000
E20.8 Other hypoparathyroidism	0.000	0.996	0.003
E20.1 Pseudohypoparathyroidism	0.000	0.996	0.003
E20.0 Idiopathic hypoparathyroidism	0.000	0.996	0.003
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.996	0.004
M87.8 Other osteonecrosis	0.000	0.996	0.004
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.996	0.003
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.996	0.003
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.996	0.003
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.996	0.003
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.996	0.003
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.996	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.996	0.004
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.000	0.996	0.003
S83.0 Dislocation of patella	0.000	0.996	0.003
E27 Other disorders of adrenal gland	0.000	0.996	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.997	0.003
C53 Malignant neoplasm of cervix uteri	0.000	0.997	0.003
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.997	0.003
G12.2 Motor neuron disease	0.000	0.997	0.003
E78.1 Pure hyperglyceridaemia	0.000	0.997	0.003
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.997	0.003
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.997	0.003
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.997	0.003
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.997	0.003
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.997	0.003
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.997	0.003
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.997	0.003
D45 Polycythaemia vera	0.000	0.997	0.003
T78.0 Anaphylactic shock due to adverse food reaction	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.997	0.003
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.997	0.003
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.997	0.003
E21.4 Other specified disorders of parathyroid gland	0.000	0.997	0.003
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.997	0.003
E34 Other endocrine disorders	0.001	0.997	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.997	0.003
E78.3 Hyperchylomicronaemia	0.000	0.997	0.003
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.997	0.003
M87.3 Other secondary osteonecrosis	0.000	0.997	0.003
O66 Other obstructed labour	0.003	0.997	0.000
M87.1 Osteonecrosis due to drugs	0.000	0.997	0.003
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E66.1 Drug-induced obesity	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
M87.89 Other osteonecrosis (Site unspecified)	0.000	0.997	0.003
M87.88 Other osteonecrosis (Other)	0.000	0.997	0.003
M87.87 Other osteonecrosis (Ankle and foot)	0.000	0.997	0.003
M87.86 Other osteonecrosis (Lower leg)	0.000	0.997	0.003
M87.84 Other osteonecrosis (Hand)	0.000	0.997	0.003
M87.83 Other osteonecrosis (Forearm)	0.000	0.997	0.003
M87.82 Other osteonecrosis (Upper arm)	0.000	0.997	0.003
M87.81 Other osteonecrosis (Shoulder region)	0.000	0.997	0.003
M87.80 Other osteonecrosis (Multiple sites)	0.000	0.997	0.003
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
K07.3 Anomalies of tooth position	0.000	0.997	0.003
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations