TreeWAS – Variant ID: rs4243971

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.738	0.262	0.000
Z42.1 Follow-up care involving plastic surgery of breast	0.130	0.870	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.900	0.100
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.918	0.082
I60 Subarachnoid haemorrhage	0.075	0.925	0.000
I10-I15 Hypertensive diseases	0.075	0.925	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.075	0.925	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.928	0.072
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.069	0.931	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.933	0.067
I60.8 Other subarachnoid haemorrhage	0.065	0.934	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.065	0.935	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.064	0.936	0.000
O16 Unspecified maternal hypertension	0.000	0.936	0.064
I61 Intracerebral haemorrhage	0.064	0.936	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.936	0.064
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.937	0.063
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.061	0.938	0.000
O14.9 Preeclampsia, unspecified	0.000	0.939	0.061
I61.5 Intracerebral haemorrhage, intraventricular	0.060	0.940	0.000
O15 Eclampsia	0.000	0.941	0.059
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.058	0.942	0.000
I60-I69 Cerebrovascular diseases	0.058	0.942	0.000
O14.0 Moderate preeclampsia	0.000	0.943	0.057
O12.0 Gestational oedema	0.000	0.944	0.056
I61.8 Other intracerebral haemorrhage	0.055	0.945	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.054	0.946	0.000
I13 Hypertensive heart and renal disease	0.054	0.946	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.053	0.947	0.000
O14.1 Severe preeclampsia	0.000	0.948	0.052
O14.2 HELLP syndrome	0.000	0.948	0.051
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.949	0.051
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.051	0.949	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.050	0.950	0.000
O12.1 Gestational proteinuria	0.000	0.950	0.050
I60.4 Subarachnoid haemorrhage from basilar artery	0.050	0.950	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.049	0.950	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.049	0.951	0.000
O12.2 Gestational oedema with proteinuria	0.000	0.952	0.048
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.047	0.953	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.046	0.954	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.954	0.046
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.954	0.046
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.954	0.046
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.954	0.046
I68.0 Cerebral amyloid angiopathy	0.045	0.955	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.955	0.045
I62 Other nontraumatic intracranial haemorrhage	0.043	0.957	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.957	0.042
O15.2 Eclampsia in the puerperium	0.000	0.957	0.042
O15.1 Eclampsia in labour	0.000	0.957	0.042
O15.0 Eclampsia in pregnancy	0.000	0.957	0.042
I61.3 Intracerebral haemorrhage in brain stem	0.042	0.958	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.040	0.960	0.000
I15 Secondary hypertension	0.040	0.960	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.039	0.961	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.039	0.961	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.039	0.961	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.038	0.961	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.038	0.962	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.036	0.964	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.036	0.964	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.036	0.964	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.036	0.964	0.000
I69 Sequelae of cerebrovascular disease	0.036	0.964	0.000
C92.0 Acute myeloid leukaemia	0.036	0.964	0.000
I11 Hypertensive heart disease	0.035	0.965	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.035	0.965	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.035	0.965	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.033	0.967	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.033	0.967	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.033	0.967	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.033	0.967	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.033	0.967	0.000
I15.0 Renovascular hypertension	0.033	0.967	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.032	0.968	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.030	0.970	0.000
I62.1 Nontraumatic extradural haemorrhage	0.030	0.970	0.000
I15.8 Other secondary hypertension	0.029	0.971	0.000
I15.2 Hypertension secondary to endocrine disorders	0.029	0.971	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.028	0.972	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.027	0.972	0.000
Z00.0 General medical examination	0.025	0.975	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.025	0.975	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.023	0.977	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.022	0.978	0.000
I12 Hypertensive renal disease	0.022	0.978	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.019	0.980	0.000
I15.1 Hypertension secondary to other renal disorders	0.019	0.981	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.018	0.982	0.000
I15.9 Seconday hypertension, unspecified	0.017	0.982	0.001
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.018	0.982	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.017	0.982	0.000
S00.9 Superficial injury of head, part unspecified	0.000	0.983	0.017
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.017	0.983	0.000
Chapter IX Diseases of the circulatory system	0.016	0.984	0.000
I65.1 Occlusion and stenosis of basilar artery	0.016	0.984	0.000
Z42 Follow-up care involving plastic surgery	0.015	0.985	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.015	0.985	0.000
I27.0 Primary pulmonary hypertension	0.015	0.985	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.014	0.986	0.000
I27 Other pulmonary heart diseases	0.014	0.986	0.000
I69.3 Sequelae of cerebral infarction	0.014	0.986	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.014	0.986	0.000
C92 Myeloid leukaemia	0.013	0.987	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.013	0.987	0.000
I00-I02 Acute rheumatic fever	0.012	0.987	0.000
Z00.8 Other general examinations	0.012	0.988	0.000
I27.9 Pulmonary heart disease, unspecified	0.012	0.988	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.011	0.989	0.000
Z42.8 Follow-up care involving plastic surgery of other body part	0.011	0.989	0.000
Z42.9 Follow-up care involving plastic surgery, unspecified	0.011	0.989	0.000
C92.5 Acute myelomonocytic leukaemia	0.010	0.990	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.010	0.990	0.000
C92.7 Other myeloid leukaemia	0.010	0.990	0.000
I27.1 Kyphoscoliotic heart disease	0.010	0.990	0.000
Z00.3 Examination for adolescent development state	0.010	0.990	0.000
Z00.2 Examination for period of rapid growth in childhood	0.010	0.990	0.000
Z00.1 Routine child health examination	0.010	0.990	0.000
C92.4 Acute promyelocytic leukaemia	0.010	0.990	0.000
I00 Rheumatic fever without mention of heart involvement	0.010	0.990	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.010	0.990	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.010	0.990	0.000
C92.3 Myeloid sarcoma	0.010	0.990	0.000
C92.2 Subacute myeloid leukaemia	0.010	0.990	0.000
C92.9 Myeloid leukaemia, unspecified	0.010	0.990	0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.009	0.990	0.000
G43.9 Migraine, unspecified	0.009	0.991	0.000
I28 Other diseases of pulmonary vessels	0.009	0.991	0.000
I02 Rheumatic chorea	0.009	0.991	0.000
I01 Rheumatic fever with heart involvement	0.009	0.991	0.000
I67 Other cerebrovascular diseases	0.009	0.991	0.000
E06.3 Autoimmune thyroiditis	0.000	0.991	0.009
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.009	0.991	0.000
I65.2 Occlusion and stenosis of carotid artery	0.009	0.991	0.000
I27.2 Other secondary pulmonary hypertension	0.009	0.991	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.008	0.991	0.000
Z00.5 Examination of potential donor of organ and tissue	0.008	0.992	0.000
I12.9 Hypertensive renal disease without renal failure	0.008	0.992	0.000
I26 Pulmonary embolism	0.008	0.992	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.008	0.992	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.008	0.992	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.008	0.992	0.000
I27.8 Other specified pulmonary heart diseases	0.007	0.992	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.007	0.993	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.007	0.993	0.000
I28.1 Aneurysm of pulmonary artery	0.007	0.993	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.007	0.993	0.000
I01.8 Other acute rheumatic heart disease	0.007	0.993	0.000
I01.2 Acute rheumatic myocarditis	0.007	0.993	0.000
I01.1 Acute rheumatic endocarditis	0.007	0.993	0.000
I01.0 Acute rheumatic pericarditis	0.007	0.993	0.000
I02.9 Rheumatic chorea without heart involvement	0.007	0.993	0.000
I02.0 Rheumatic chorea with heart involvement	0.007	0.993	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.007	0.993	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.007	0.993	0.000
I67.5 Moyamoya disease	0.007	0.993	0.000
I67.4 Hypertensive encephalopathy	0.007	0.993	0.000
I67.3 Progressive vascular leukoencephalopathy	0.007	0.993	0.000
I67.1 Cerebral aneurysm, nonruptured	0.006	0.994	0.000
G43 Migraine	0.006	0.994	0.000
C92.1 Chronic myeloid leukaemia	0.006	0.994	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.994	0.006
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.006	0.994	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.994	0.006
R82 Other abnormal findings in urine	0.000	0.994	0.006
I28.8 Other specified diseases of pulmonary vessels	0.006	0.994	0.000
I63 Cerebral infarction	0.006	0.994	0.000
G43.2 Status migrainosus	0.006	0.994	0.000
G43.1 Migraine with aura [classical migraine]	0.006	0.994	0.000
H11.3 Conjunctival haemorrhage	0.000	0.994	0.006
R82.7 Abnormal findings on microbiological examination of urine	0.000	0.995	0.005
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.995	0.005
Z98.8 Other specified postsurgical states	0.000	0.995	0.005
K83.8 Other specified diseases of biliary tract	0.005	0.995	0.000
R82.1 Myoglobinuria	0.000	0.995	0.005
Z46.8 Fitting and adjustment of other specified devices	0.005	0.995	0.000
G43.3 Complicated migraine	0.005	0.995	0.000
G43.0 Migraine without aura [common migraine]	0.005	0.995	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.000	0.995	0.005
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.005	0.995	0.000
H11 Other disorders of conjunctiva	0.000	0.995	0.005
Z42.0 Follow-up care involving plastic surgery of head and neck	0.005	0.995	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.004	0.995	0.000
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.000	0.995	0.005
R82.3 Haemoglobinuria	0.000	0.995	0.005
R82.2 Biliuria	0.000	0.995	0.005
R82.0 Chyluria	0.000	0.995	0.005
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.005	0.995	0.000
H11.9 Disorder of conjunctiva, unspecified	0.000	0.995	0.005
E06 Thyroiditis	0.000	0.995	0.005
H11.1 Conjunctival degenerations and deposits	0.000	0.995	0.004
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.004	0.996	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.004	0.996	0.000
I12.0 Hypertensive renal disease with renal failure	0.004	0.996	0.000
R82.4 Acetonuria	0.000	0.996	0.004
G43.8 Other migraine	0.004	0.996	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.004	0.996	0.000
I63.8 Other cerebral infarction	0.004	0.996	0.000
H11.2 Conjunctival scars	0.000	0.996	0.004
I67.9 Cerebrovascular disease, unspecified	0.004	0.996	0.000
I73.0 Raynaud's syndrome	0.004	0.996	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.000	0.996	0.004
E06.5 Other chronic thyroiditis	0.000	0.996	0.004
E10.4 With neurological complications	0.000	0.996	0.004
H11.8 Other specified disorders of conjunctiva	0.000	0.996	0.004
H11.0 Pterygium	0.000	0.996	0.004
N64.4 Mastodynia	0.004	0.996	0.000
Z46 Fitting and adjustment of other devices	0.004	0.996	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.003	0.996	0.000
E06.4 Drug-induced thyroiditis	0.000	0.996	0.003
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.996	0.003
E06.0 Acute thyroiditis	0.000	0.996	0.003
Z89.6 Acquired absence of leg above knee	0.000	0.996	0.004
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.996	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
Z46.3 Fitting and adjustment of dental prosthetic device	0.003	0.997	0.000
Z46.4 Fitting and adjustment of orthodontic device	0.003	0.997	0.000
E06.1 Subacute thyroiditis	0.000	0.997	0.003
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.003	0.997	0.000
Z46.7 Fitting and adjustment of orthopaedic device	0.003	0.997	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.000	0.997	0.003
E88 Other metabolic disorders	0.003	0.997	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.997	0.003
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.003	0.997	0.000
Z46.1 Fitting and adjustment of hearing aid	0.003	0.997	0.000
S51.0 Open wound of elbow	0.000	0.997	0.003
I67.8 Other specified cerebrovascular diseases	0.003	0.997	0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses	0.003	0.997	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.997	0.003
I50.1 Left ventricular failure	0.003	0.997	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.003	0.997	0.000
R23.1 Pallor	0.000	0.997	0.003
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances	0.003	0.997	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.003	0.997	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.997	0.003
Q87.4 Marfan's syndrome	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
Z46.9 Fitting and adjustment of other unspecified device	0.003	0.997	0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses	0.003	0.997	0.000
E10.7 With multiple complications	0.000	0.997	0.003
C26.0 Intestinal tract, part unspecified	0.003	0.997	0.000
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.003	0.997	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
I67.2 Cerebral atherosclerosis	0.003	0.997	0.000
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.003	0.997	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.003	0.997	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.003	0.997	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.997	0.003
E88.8 Other specified metabolic disorders	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.003	0.997	0.000
O24 Diabetes mellitus in pregnancy	0.000	0.997	0.003
T92 Sequelae of injuries of upper limb	0.003	0.997	0.000
E10.0 With coma	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
K83 Other diseases of biliary tract	0.003	0.997	0.000
E88.9 Metabolic disorder, unspecified	0.002	0.997	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.997	0.003
E10.6 With other specified complications	0.000	0.997	0.002
I05-I09 Chronic rheumatic heart diseases	0.002	0.997	0.000
E88.2 Lipomatosis, not elsewhere classified	0.002	0.997	0.000
K83.1 Obstruction of bile duct	0.003	0.997	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.002	0.998	0.000
Z45.8 Adjustment and management of other implanted devices	0.002	0.998	0.000
E88.3 Tumour lysis syndrome	0.002	0.998	0.000
M06.0 Seronegative rheumatoid arthritis	0.002	0.998	0.000
T92.0 Sequelae of open wound of upper limb	0.002	0.998	0.000
E10.9 Without complications	0.000	0.998	0.002
E10.3 With ophthalmic complications	0.000	0.998	0.002
J86.9 Pyothorax without fistula	0.000	0.998	0.002
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.002	0.998	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
L92.0 Granuloma annulare	0.002	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
Z89 Acquired absence of limb	0.000	0.998	0.002
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.998	0.002
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.998	0.002
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.998	0.002
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
E10.8 With unspecified complications	0.000	0.998	0.002
K83.3 Fistula of bile duct	0.002	0.998	0.000
O43.8 Other placental disorders	0.002	0.998	0.000
K29.3 Chronic superficial gastritis	0.002	0.998	0.000
K83.2 Perforation of bile duct	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.998	0.002
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.002	0.998	0.000
I06 Rheumatic aortic valve diseases	0.002	0.998	0.000
I70 Atherosclerosis	0.002	0.998	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.002	0.998	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.998	0.002
K83.4 Spasm of sphincter of Oddi	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
I44.0 Atrioventricular block, first degree	0.002	0.998	0.000
I70.1 Atherosclerosis of renal artery	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.002	0.998	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
Q21.1 Atrial septal defect	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.002
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.000	0.998	0.002
Q21 Congenital malformations of cardiac septa	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.000	0.998	0.002
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
K83.5 Biliary cyst	0.002	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.998	0.002
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.002
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.002
S52.01 Fracture of upper end of ulna (open)	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
Y45.1 Salicylates	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.000	0.998	0.002
Q21.3 Tetralogy of Fallot	0.000	0.998	0.002
R63.5 Abnormal weight gain	0.002	0.998	0.000
Z29.8 Other specified prophylactic measures	0.000	0.998	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.002	0.998	0.000
E10.2 With renal complications	0.000	0.998	0.002
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
L94.2 Calcinosis cutis	0.000	0.998	0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
Q24.0 Dextrocardia	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
Q24.6 Congenital heart block	0.000	0.998	0.002
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.000	0.998	0.002
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.998	0.002
C15.5 Lower third of oesophagus	0.000	0.998	0.002
S51 Open wound of forearm	0.000	0.998	0.002
I70.11 Atherosclerosis of renal artery (with gangrene)	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.002	0.998	0.000
J20.9 Acute bronchitis, unspecified	0.002	0.998	0.000
H10-H13 Disorders of conjunctiva	0.000	0.998	0.002
M77.02 Medial epicondylitis (Upper arm)	0.000	0.998	0.002
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.998	0.000
I70.8 Atherosclerosis of other arteries	0.002	0.998	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.000	0.998	0.002
H81.0 Meniere's disease	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.000	0.998	0.002
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.002	0.998	0.000
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.000	0.998	0.002
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.998	0.002
I06.0 Rheumatic aortic stenosis	0.001	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.998	0.001
O23.2 Infections of urethra in pregnancy	0.000	0.998	0.001
O23.1 Infections of bladder in pregnancy	0.000	0.998	0.001
Q21.4 Aortopulmonary septal defect	0.000	0.998	0.002
Q21.2 Atrioventricular septal defect	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.001
M77.9 Enthesopathy, unspecified	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.000	0.998	0.002
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.002
T81.9 Unspecified complication of procedure	0.002	0.998	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.001	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.001	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.998	0.000
I09.0 Rheumatic myocarditis	0.001	0.998	0.000
Q21.8 Other congenital malformations of cardiac septa	0.000	0.998	0.001
T20.1 Burn of first degree of head and neck	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.000	0.998	0.001
O22 Venous complications in pregnancy	0.000	0.998	0.002
O25 Malnutrition in pregnancy	0.000	0.998	0.001
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
Y83.3 Surgical operation with formation of external stoma	0.002	0.998	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.002	0.998	0.000
S52.0 Fracture of upper end of ulna	0.000	0.998	0.002
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.001
Z89.2 Acquired absence of upper limb above wrist	0.000	0.998	0.001
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
I77.2 Rupture of artery	0.001	0.998	0.000
K92.9 Disease of digestive system, unspecified	0.000	0.998	0.002
Q67.5 Congenital deformity of spine	0.001	0.998	0.000
I99 Other and unspecified disorders of circulatory system	0.001	0.998	0.000
M77.92 Enthesopathy, unspecified (Upper arm)	0.000	0.998	0.001
H10.4 Chronic conjunctivitis	0.000	0.998	0.001
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.998	0.001
Q24.5 Malformation of coronary vessels	0.000	0.998	0.001
X62.9 Unspecified place	0.002	0.998	0.000
H10 Conjunctivitis	0.000	0.998	0.001
I77 Other disorders of arteries and arterioles	0.002	0.998	0.000
O22.4 Haemorrhoids in pregnancy	0.000	0.998	0.001
E22.1 Hyperprolactinaemia	0.001	0.998	0.000
M89.8 Other specified disorders of bone	0.000	0.998	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.001	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.001
I73.9 Peripheral vascular disease, unspecified	0.002	0.998	0.000
O00.9 Ectopic pregnancy, unspecified	0.000	0.998	0.001
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.998	0.001
I70.81 Atherosclerosis of other arteries (with gangrene)	0.001	0.999	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.999	0.001
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
Z80.4 Family history of malignant neoplasm of genital organs	0.001	0.999	0.000
R80 Isolated proteinuria	0.000	0.999	0.001
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.999	0.001
M77.0 Medial epicondylitis	0.000	0.999	0.001
N30.3 Trigonitis	0.001	0.999	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.000	0.999	0.001
Q87.3 Congenital malformation syndromes involving early overgrowth	0.000	0.999	0.001
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.000	0.999	0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.001	0.999	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.001	0.999	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.001	0.999	0.000
M77.99 Enthesopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M77.98 Enthesopathy, unspecified (Other)	0.000	0.999	0.001
M77.93 Enthesopathy, unspecified (Forearm)	0.000	0.999	0.001
M77.90 Enthesopathy, unspecified (Multiple sites)	0.000	0.999	0.001
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.999	0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
I73.8 Other specified peripheral vascular diseases	0.001	0.999	0.000
N97.4 Female infertility associated with male factors	0.000	0.999	0.001
N97.0 Female infertility associated with anovulation	0.000	0.999	0.001
S12.0 Fracture of first cervical vertebra	0.000	0.999	0.001
I07 Rheumatic tricuspid valve diseases	0.001	0.999	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.999	0.001
O22.9 Venous complication in pregnancy, unspecified	0.000	0.999	0.001
O22.8 Other venous complications in pregnancy	0.000	0.999	0.001
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.999	0.001
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.999	0.001
S12 Fracture of neck	0.000	0.999	0.001
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M77.94 Enthesopathy, unspecified (Hand)	0.000	0.999	0.001
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.001	0.999	0.000
M77.4 Metatarsalgia	0.000	0.999	0.001
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.999	0.001
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.999	0.001
O29.6 Failed or difficult intubation during pregnancy	0.000	0.999	0.001
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.999	0.001
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.999	0.001
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.999	0.001
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.999	0.001
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.999	0.001
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.999	0.001
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.000	0.999	0.001
R40.0 Somnolence	0.000	0.999	0.001
T80 Complications following infusion, transfusion and therapeutic injection	0.001	0.999	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.001	0.999	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.001	0.999	0.000
T93.1 Sequelae of fracture of femur	0.001	0.999	0.000
H10.5 Blepharoconjunctivitis	0.000	0.999	0.001
H10.3 Acute conjunctivitis, unspecified	0.000	0.999	0.001
I77.5 Necrosis of artery	0.001	0.999	0.000
I77.4 Coeliac artery compression syndrome	0.001	0.999	0.000
I77.0 Arteriovenous fistula, acquired	0.001	0.999	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.000	0.999	0.001
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.001	0.999	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.999	0.000
H10.2 Other acute conjunctivitis	0.000	0.999	0.001
L43.8 Other lichen planus	0.001	0.999	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations