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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4246850
log Bayes Factor = 12.9549
Chromosome 9   position 20,928,037  (GRCh37) Explore rs4246850 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I20.9 Angina pectoris, unspecified
0.000 0.000 1.000
I25.2 Old myocardial infarction
0.000 0.001 0.999
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.002 0.998
I24 Other acute ischaemic heart diseases
0.000 0.006 0.994
Z95.1 Presence of aortocoronary bypass graft
0.000 0.012 0.988
I24.8 Other forms of acute ischaemic heart disease
0.000 0.021 0.979
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.022 0.978
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.088 0.912
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.101 0.899
Z95.0 Presence of cardiac pacemaker
0.000 0.109 0.891
I21 Acute myocardial infarction
0.000 0.111 0.889
I20.8 Other forms of angina pectoris
0.000 0.114 0.886
I22 Subsequent myocardial infarction
0.000 0.153 0.847
I20.0 Unstable angina
0.000 0.159 0.841
I25.5 Ischaemic cardiomyopathy
0.000 0.190 0.810
I21.4 Acute subendocardial myocardial infarction
0.000 0.206 0.794
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.237 0.763
I21.9 Acute myocardial infarction, unspecified
0.000 0.247 0.753
I20.1 Angina pectoris with documented spasm
0.000 0.252 0.748
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.254 0.746
Z95.4 Presence of other heart-valve replacement
0.000 0.258 0.742
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.265 0.735
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.274 0.726
I25.3 Aneurysm of heart
0.000 0.277 0.723
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I25.4 Coronary artery aneurysm
0.000 0.283 0.717
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.283 0.717
I23 Certain current complications following acute myocardial infarction
0.000 0.283 0.717
I24.1 Dressler's syndrome
0.000 0.287 0.712
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.296 0.704
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.299 0.701
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.357 0.643
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.363 0.637
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.380 0.620
I22.8 Subsequent myocardial infarction of other sites
0.000 0.389 0.611
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.393 0.607
Z95.3 Presence of xenogenic heart valve
0.000 0.400 0.600
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.419 0.581
I23.8 Other current complications following acute myocardial infarction
0.000 0.486 0.514
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.486 0.514
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.486 0.514
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.486 0.514
Z95.2 Presence of prosthetic heart valve
0.000 0.587 0.412
Chapter IX Diseases of the circulatory system
0.000 0.665 0.335
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.708 0.292
I05-I09 Chronic rheumatic heart diseases
0.000 0.712 0.288
I74 Arterial embolism and thrombosis
0.000 0.725 0.275
I30-I52 Other forms of heart disease
0.000 0.727 0.273
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.728 0.272
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.733 0.267
I50 Heart failure
0.000 0.736 0.264
I44 Atrioventricular and left bundle-branch block
0.000 0.743 0.257
I08 Multiple valve diseases
0.000 0.745 0.255
I10-I15 Hypertensive diseases
0.000 0.747 0.253
I71 Aortic aneurysm and dissection
0.000 0.748 0.252
I50.1 Left ventricular failure
0.000 0.753 0.247
I47 Paroxysmal tachycardia
0.000 0.755 0.245
I00-I02 Acute rheumatic fever
0.000 0.760 0.240
I47.2 Ventricular tachycardia
0.000 0.761 0.239
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.762 0.238
I12 Hypertensive renal disease
0.000 0.762 0.238
I72 Other aneurysm
0.000 0.766 0.234
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.766 0.234
I50.9 Heart failure, unspecified
0.000 0.767 0.233
I42 Cardiomyopathy
0.000 0.768 0.232
I44.7 Left bundle-branch block, unspecified
0.000 0.771 0.229
I95 Hypotension
0.000 0.772 0.228
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.772 0.228
I44.1 Atrioventricular block, second degree
0.000 0.773 0.227
I46 Cardiac arrest
0.000 0.775 0.225
I12.0 Hypertensive renal disease with renal failure
0.000 0.778 0.222
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.780 0.220
I70 Atherosclerosis
0.000 0.782 0.218
I05 Rheumatic mitral valve diseases
0.000 0.789 0.210
I09 Other rheumatic heart diseases
0.000 0.793 0.207
I06 Rheumatic aortic valve diseases
0.000 0.793 0.207
I42.9 Cardiomyopathy, unspecified
0.000 0.797 0.203
I07 Rheumatic tricuspid valve diseases
0.000 0.797 0.203
I42.2 Other hypertrophic cardiomyopathy
0.000 0.798 0.202
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.801 0.199
I44.3 Other and unspecified atrioventricular block
0.000 0.802 0.198
I08.8 Other multiple valve diseases
0.000 0.803 0.197
I50.0 Congestive heart failure
0.000 0.803 0.197
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.803 0.197
I74.8 Embolism and thrombosis of other arteries
0.000 0.803 0.197
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.803 0.197
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.803 0.197
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.803 0.197
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.804 0.196
I52 Other heart disorders in diseases classified elsewhere
0.000 0.804 0.195
I48 Atrial fibrillation and flutter
0.000 0.804 0.195
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.804 0.195
I41 Myocarditis in diseases classified elsewhere
0.000 0.804 0.195
I40 Acute myocarditis
0.000 0.804 0.195
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.804 0.195
I32 Pericarditis in diseases classified elsewhere
0.000 0.804 0.195
I44.0 Atrioventricular block, first degree
0.000 0.806 0.194
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.807 0.193
I36 Nonrheumatic tricuspid valve disorders
0.000 0.807 0.193
I46.0 Cardiac arrest with successful resuscitation
0.000 0.807 0.193
I12.9 Hypertensive renal disease without renal failure
0.000 0.807 0.193
I37 Pulmonary valve disorders
0.000 0.807 0.193
I95.1 Orthostatic hypotension
0.000 0.807 0.193
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.809 0.191
I72.3 Aneurysm of iliac artery
0.000 0.811 0.189
I44.6 Other and unspecified fascicular block
0.000 0.811 0.188
I78 Diseases of capillaries
0.000 0.812 0.188
I95.9 Hypotension, unspecified
0.000 0.813 0.187
I44.5 Left posterior fascicular block
0.000 0.815 0.185
I44.4 Left anterior fascicular block
0.000 0.815 0.185
I08.9 Multiple valve disease, unspecified
0.000 0.817 0.183
I13 Hypertensive heart and renal disease
0.000 0.818 0.182
I15 Secondary hypertension
0.000 0.818 0.182
I51 Complications and ill-defined descriptions of heart disease
0.000 0.819 0.181
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.819 0.181
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.819 0.181
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.819 0.181
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.819 0.181
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.819 0.181
I47.0 Reentry ventricular arrhythmia
0.000 0.821 0.179
I05.9 Mitral valve disease, unspecified
0.000 0.821 0.179
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.821 0.179
I71.0 Dissection of aorta [any part]
0.000 0.822 0.178
I11 Hypertensive heart disease
0.000 0.824 0.176
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.826 0.174
I74.5 Embolism and thrombosis of iliac artery
0.000 0.827 0.173
I72.4 Aneurysm of artery of lower extremity
0.000 0.827 0.173
I30 Acute pericarditis
0.000 0.827 0.173
I02 Rheumatic chorea
0.000 0.827 0.172
I01 Rheumatic fever with heart involvement
0.000 0.827 0.172
I00 Rheumatic fever without mention of heart involvement
0.000 0.827 0.172
I45 Other conduction disorders
0.000 0.829 0.171
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.832 0.168
I33 Acute and subacute endocarditis
0.000 0.832 0.168
I72.9 Aneurysm of unspecified site
0.000 0.832 0.168
I72.8 Aneurysm of other specified arteries
0.000 0.832 0.168
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.832 0.168
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.832 0.168
I72.2 Aneurysm of renal artery
0.000 0.832 0.168
I72.1 Aneurysm of artery of upper extremity
0.000 0.832 0.168
I72.0 Aneurysm of carotid artery
0.000 0.832 0.168
I70.0 Atherosclerosis of aorta
0.000 0.832 0.168
I42.8 Other cardiomyopathies
0.000 0.833 0.167
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.833 0.167
I42.6 Alcoholic cardiomyopathy
0.000 0.833 0.167
I42.5 Other restrictive cardiomyopathy
0.000 0.833 0.167
I42.4 Endocardial fibroelastosis
0.000 0.833 0.167
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.833 0.167
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.835 0.165
I95.8 Other hypotension
0.000 0.836 0.164
I95.0 Idiopathic hypotension
0.000 0.836 0.164
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.836 0.163
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.836 0.163
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.836 0.163
I98.0 Cardiovascular syphilis
0.000 0.836 0.163
I46.1 Sudden cardiac death, so described
0.000 0.838 0.162
I51.8 Other ill-defined heart diseases
0.000 0.840 0.160
I46.9 Cardiac arrest, unspecified
0.000 0.841 0.159
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.842 0.158
I79.1 Aortitis in diseases classified elsewhere
0.000 0.842 0.158
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.842 0.158
I70.9 Generalised and unspecified atherosclerosis
0.000 0.844 0.156
I70.8 Atherosclerosis of other arteries
0.000 0.844 0.156
I70.1 Atherosclerosis of renal artery
0.000 0.844 0.156
I44.2 Atrioventricular block, complete
0.000 0.844 0.156
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.845 0.155
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.847 0.153
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.848 0.152
I08.0 Disorders of both mitral and aortic valves
0.000 0.848 0.152
I05.8 Other mitral valve diseases
0.000 0.849 0.151
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.851 0.148
I06.8 Other rheumatic aortic valve diseases
0.000 0.851 0.148
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.851 0.148
I06.1 Rheumatic aortic insufficiency
0.000 0.851 0.148
I06.0 Rheumatic aortic stenosis
0.000 0.851 0.148
I09.9 Rheumatic heart disease, unspecified
0.000 0.851 0.148
I09.8 Other specified rheumatic heart diseases
0.000 0.851 0.148
I09.2 Chronic rheumatic pericarditis
0.000 0.851 0.148
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.851 0.148
I09.0 Rheumatic myocarditis
0.000 0.851 0.148
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.852 0.148
I07.9 Tricuspid valve disease, unspecified
0.000 0.854 0.146
I07.8 Other tricuspid valve diseases
0.000 0.854 0.146
I07.2 Tricuspid stenosis with insufficiency
0.000 0.854 0.146
I07.0 Tricuspid stenosis
0.000 0.854 0.146
I45.6 Preexcitation syndrome
0.000 0.855 0.145
I07.1 Tricuspid insufficiency
0.000 0.857 0.143
I05.2 Mitral stenosis with insufficiency
0.000 0.857 0.142
I99 Other and unspecified disorders of circulatory system
0.000 0.858 0.141
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.859 0.140
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.859 0.140
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.859 0.140
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.859 0.140
I40.9 Acute myocarditis, unspecified
0.000 0.859 0.140
I40.8 Other acute myocarditis
0.000 0.859 0.140
I40.1 Isolated myocarditis
0.000 0.859 0.140
I40.0 Infective myocarditis
0.000 0.859 0.140
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.859 0.140
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.859 0.140
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.859 0.140
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.859 0.140
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.859 0.140
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.859 0.140
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.859 0.140
I48.4 Atypical atrial flutter
0.000 0.859 0.140
I48.3 Typical atrial flutter
0.000 0.859 0.140
I48.2 Chronic atrial fibrillation
0.000 0.859 0.140
I48.1 Persistent atrial fibrillation
0.000 0.859 0.140
I48.0 Paroxysmal atrial fibrillation
0.000 0.859 0.140
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.859 0.140
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.859 0.140
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.859 0.140
I05.1 Rheumatic mitral insufficiency
0.000 0.860 0.140
I97.1 Other functional disturbances following cardiac surgery
0.000 0.861 0.139
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.861 0.139
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.861 0.139
I97.0 Postcardiotomy syndrome
0.000 0.861 0.139
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.861 0.138
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.861 0.138
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.861 0.138
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.861 0.138
I95.2 Hypotension due to drugs
0.000 0.861 0.138
I37.9 Pulmonary valve disorder, unspecified
0.000 0.862 0.138
I37.8 Other pulmonary valve disorders
0.000 0.862 0.138
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.862 0.138
I37.0 Pulmonary valve stenosis
0.000 0.862 0.138
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.863 0.136
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.864 0.136
I37.1 Pulmonary valve insufficiency
0.000 0.865 0.135
I78.9 Disease of capillaries, unspecified
0.000 0.865 0.135
I78.8 Other diseases of capillaries
0.000 0.865 0.135
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.865 0.135
I05.0 Mitral stenosis
0.000 0.866 0.134
I51.9 Heart disease, unspecified
0.000 0.868 0.132
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.868 0.132
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.869 0.130
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.869 0.130
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.869 0.130
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.869 0.130
I15.9 Seconday hypertension, unspecified
0.000 0.869 0.130
I15.8 Other secondary hypertension
0.000 0.869 0.130
I15.2 Hypertension secondary to endocrine disorders
0.000 0.869 0.130
I15.0 Renovascular hypertension
0.000 0.869 0.130
I15.1 Hypertension secondary to other renal disorders
0.000 0.869 0.130
I51.5 Myocardial degeneration
0.000 0.870 0.130
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.870 0.130
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.870 0.130
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.870 0.130
I45.5 Other specified heart block
0.000 0.871 0.129
I28 Other diseases of pulmonary vessels
0.000 0.871 0.128
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.874 0.126
I51.0 Cardiac septal defect, acquired
0.000 0.876 0.124
I30.8 Other forms of acute pericarditis
0.000 0.876 0.124
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.876 0.124
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.876 0.124
I01.8 Other acute rheumatic heart disease
0.000 0.876 0.124
I01.2 Acute rheumatic myocarditis
0.000 0.876 0.124
I01.1 Acute rheumatic endocarditis
0.000 0.876 0.124
I01.0 Acute rheumatic pericarditis
0.000 0.876 0.124
I02.9 Rheumatic chorea without heart involvement
0.000 0.876 0.124
I02.0 Rheumatic chorea with heart involvement
0.000 0.876 0.124
I45.8 Other specified conduction disorders
0.000 0.877 0.123
I45.4 Nonspecific intraventricular block
0.000 0.877 0.123
I45.3 Trifascicular block
0.000 0.877 0.123
I45.0 Right fascicular block
0.000 0.877 0.123
I27 Other pulmonary heart diseases
0.000 0.878 0.122
M79.6 Pain in limb
0.121 0.879 0.000
I33.9 Acute endocarditis, unspecified
0.000 0.879 0.121
M79.67 Pain in limb (Ankle and foot)
0.121 0.879 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.880 0.120
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.880 0.120
I73 Other peripheral vascular diseases
0.000 0.882 0.118
M79.66 Pain in limb (Lower leg)
0.117 0.883 0.000
I30.1 Infective pericarditis
0.000 0.883 0.117
I49 Other cardiac arrhythmias
0.000 0.885 0.115
I42.0 Dilated cardiomyopathy
0.000 0.886 0.114
M79.60 Pain in limb (Multiple sites)
0.114 0.886 0.000
I51.6 Cardiovascular disease, unspecified
0.000 0.886 0.113
I78.1 Naevus, nonneoplastic
0.000 0.887 0.113
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.888 0.112
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.888 0.112
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.888 0.112
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.888 0.112
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.888 0.112
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.888 0.112
I30.9 Acute pericarditis, unspecified
0.000 0.889 0.110
I21.1 Acute transmural myocardial infarction of inferior wall
0.001 0.890 0.109
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.891 0.109
I31 Other diseases of pericardium
0.000 0.891 0.109
I51.4 Myocarditis, unspecified
0.000 0.894 0.106
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.895 0.105
I51.7 Cardiomegaly
0.000 0.895 0.105
M79.65 Pain in limb (Pelvic region and thigh)
0.105 0.895 0.000
I45.2 Bifascicular block
0.000 0.896 0.104
I45.9 Conduction disorder, unspecified
0.000 0.896 0.104
M79.68 Pain in limb (Other)
0.097 0.903 0.000
I77 Other disorders of arteries and arterioles
0.000 0.903 0.096
M79.63 Pain in limb (Forearm)
0.095 0.905 0.000
M79.64 Pain in limb (Hand)
0.094 0.906 0.000
I33.0 Acute and subacute infective endocarditis
0.000 0.906 0.093
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.908 0.092
I28.8 Other specified diseases of pulmonary vessels
0.000 0.908 0.092
I28.1 Aneurysm of pulmonary artery
0.000 0.908 0.092
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.908 0.092
I27.2 Other secondary pulmonary hypertension
0.000 0.909 0.091
I34 Nonrheumatic mitral valve disorders
0.000 0.909 0.090
I45.1 Other and unspecified right bundle-branch block
0.000 0.910 0.090
I27.8 Other specified pulmonary heart diseases
0.000 0.912 0.088
I27.1 Kyphoscoliotic heart disease
0.000 0.912 0.088
I49.8 Other specified cardiac arrhythmias
0.000 0.914 0.086
I27.9 Pulmonary heart disease, unspecified
0.000 0.915 0.085
I49.5 Sick sinus syndrome
0.000 0.915 0.085
I73.8 Other specified peripheral vascular diseases
0.000 0.915 0.085
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.915 0.085
M79.61 Pain in limb (Shoulder region)
0.084 0.916 0.000
I49.4 Other and unspecified premature depolarisation
0.000 0.916 0.084
I49.0 Ventricular fibrillation and flutter
0.000 0.917 0.082
I49.2 Junctional premature depolarisation
0.000 0.918 0.082
I27.0 Primary pulmonary hypertension
0.000 0.920 0.080
I26 Pulmonary embolism
0.000 0.921 0.079
I31.8 Other specified diseases of pericardium
0.000 0.922 0.078
I31.2 Haemopericardium, not elsewhere classified
0.000 0.922 0.078
I31.0 Chronic adhesive pericarditis
0.000 0.922 0.078
M79.69 Pain in limb (Site unspecified)
0.078 0.922 0.000
I38 Endocarditis, valve unspecified
0.001 0.925 0.074
I35 Nonrheumatic aortic valve disorders
0.000 0.927 0.073
I77.5 Necrosis of artery
0.000 0.931 0.069
I77.4 Coeliac artery compression syndrome
0.000 0.931 0.069
I77.3 Arterial fibromuscular dysplasia
0.000 0.931 0.069
I77.2 Rupture of artery
0.000 0.931 0.069
I77.0 Arteriovenous fistula, acquired
0.000 0.931 0.069
I31.3 Pericardial effusion (noninflammatory)
0.000 0.931 0.069
I49.1 Atrial premature depolarisation
0.000 0.932 0.068
I49.9 Cardiac arrhythmia, unspecified
0.000 0.933 0.067
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.934 0.066
I73.0 Raynaud's syndrome
0.000 0.934 0.066
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.934 0.065
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.935 0.065
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.935 0.065
I31.1 Chronic constrictive pericarditis
0.000 0.935 0.064
M79.62 Pain in limb (Upper arm)
0.061 0.939 0.000
I77.8 Other specified disorders of arteries and arterioles
0.000 0.943 0.057
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.943 0.057
I35.8 Other aortic valve disorders
0.000 0.946 0.054
I77.6 Arteritis, unspecified
0.000 0.947 0.053
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.948 0.052
Z98.0 Intestinal bypass and anastomosis status
0.049 0.951 0.000
I31.9 Disease of pericardium, unspecified
0.000 0.954 0.045
I35.9 Aortic valve disorder, unspecified
0.000 0.955 0.045
I49.3 Ventricular premature depolarisation
0.000 0.955 0.045
I47.1 Supraventricular tachycardia
0.000 0.955 0.044
I77.1 Stricture of artery
0.000 0.957 0.043
I34.1 Mitral (valve) prolapse
0.000 0.961 0.039
I73.9 Peripheral vascular disease, unspecified
0.000 0.962 0.038
I35.1 Aortic (valve) insufficiency
0.000 0.963 0.036
I60-I69 Cerebrovascular diseases
0.000 0.965 0.035
I67 Other cerebrovascular diseases
0.000 0.970 0.030
M79 Other soft tissue disorders, not elsewhere classified
0.028 0.972 0.000
I67.8 Other specified cerebrovascular diseases
0.000 0.972 0.028
S90-S99 Injuries to the ankle and foot
0.027 0.973 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.026 0.974 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.974 0.026
Z98 Other postsurgical states
0.026 0.974 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.974 0.025
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.974 0.025
S50-S59 Injuries to the elbow and forearm
0.025 0.975 0.000
I62 Other nontraumatic intracranial haemorrhage
0.000 0.975 0.025
S91 Open wound of ankle and foot
0.025 0.975 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.024 0.976 0.000
S40-S49 Injuries to the shoulder and upper arm
0.024 0.976 0.000
S51 Open wound of forearm
0.023 0.977 0.000
I67.9 Cerebrovascular disease, unspecified
0.000 0.977 0.023
S91.3 Open wound of other parts of foot
0.023 0.977 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.023 0.977 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.023 0.977 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.023 0.977 0.000
S51.8 Open wound of other parts of forearm
0.023 0.977 0.000
S90 Superficial injury of ankle and foot
0.022 0.977 0.000
T51 Toxic effect of alcohol
0.022 0.977 0.000
I34.0 Mitral (valve) insufficiency
0.000 0.978 0.022
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.978 0.022
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.978 0.022
I67.5 Moyamoya disease
0.000 0.978 0.022
I67.4 Hypertensive encephalopathy
0.000 0.978 0.022
I67.3 Progressive vascular leukoencephalopathy
0.000 0.978 0.022
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.978 0.022
S20-S29 Injuries to the thorax
0.022 0.978 0.000
T79-T79 Certain early complications of trauma
0.022 0.978 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.022 0.978 0.000
I61 Intracerebral haemorrhage
0.000 0.978 0.021
M79.8 Other specified soft tissue disorders
0.022 0.978 0.000
I82 Other venous embolism and thrombosis
0.000 0.979 0.021
S52 Fracture of forearm
0.021 0.979 0.000
I67.2 Cerebral atherosclerosis
0.000 0.979 0.021
S96 Injury of muscle and tendon at ankle and foot level
0.021 0.979 0.000
Z98.8 Other specified postsurgical states
0.021 0.979 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.021 0.979 0.000
S92 Fracture of foot, except ankle
0.021 0.979 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.021 0.979 0.000
M79.9 Soft tissue disorder, unspecified
0.020 0.979 0.000
M79.3 Panniculitis, unspecified
0.020 0.979 0.000
I85 Oesophageal varices
0.000 0.979 0.020
Z98.1 Arthrodesis status
0.020 0.980 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.020 0.980 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.020 0.980 0.000
T98 Sequelae of other and unspecified effects of external causes
0.020 0.980 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.980 0.020
S40 Superficial injury of shoulder and upper arm
0.020 0.980 0.000
S70-S79 Injuries to the hip and thigh
0.020 0.980 0.000
S99 Other and unspecified injuries of ankle and foot
0.020 0.980 0.000
S98 Traumatic amputation of ankle and foot
0.020 0.980 0.000
S97 Crushing injury of ankle and foot
0.020 0.980 0.000
S95 Injury of blood vessels at ankle and foot level
0.020 0.980 0.000
S94 Injury of nerves at ankle and foot level
0.020 0.980 0.000
T51.9 Alcohol, unspecified
0.020 0.980 0.000
S80-S89 Injuries to the knee and lower leg
0.020 0.980 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.019 0.980 0.000
M79.2 Neuralgia and neuritis, unspecified
0.019 0.981 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.019 0.981 0.000
I67.1 Cerebral aneurysm, nonruptured
0.000 0.981 0.019
T51.0 Ethanol
0.019 0.981 0.000
T91 Sequelae of injuries of neck and trunk
0.019 0.981 0.000
S93.1 Dislocation of toe(s)
0.019 0.981 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.019 0.981 0.000
T33-T35 Frostbite
0.019 0.981 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.019 0.981 0.000
T00-T07 Injuries involving multiple body regions
0.019 0.981 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.981 0.019
I88 Nonspecific lymphadenitis
0.000 0.981 0.019
S91.1 Open wound of toe(s) without damage to nail
0.019 0.981 0.000
S42 Fracture of shoulder and upper arm
0.019 0.981 0.000
M79.1 Myalgia
0.019 0.981 0.000
I81 Portal vein thrombosis
0.000 0.981 0.019
S41 Open wound of shoulder and upper arm
0.019 0.981 0.000
S32 Fracture of lumbar spine and pelvis
0.019 0.981 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.019 0.981 0.000
T63 Toxic effect of contact with venomous animals
0.019 0.981 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.019 0.981 0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.981 0.018
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.981 0.018
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.981 0.018
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.981 0.018
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.981 0.018
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.981 0.018
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.981 0.018
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.981 0.018
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.981 0.018
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.981 0.018
I68.0 Cerebral amyloid angiopathy
0.000 0.981 0.018
S27 Injury of other and unspecified intrathoracic organs
0.019 0.981 0.000
S56 Injury of muscle and tendon at forearm level
0.018 0.981 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.018 0.981 0.000
S93.0 Dislocation of ankle joint
0.018 0.982 0.000
S51.7 Multiple open wounds of forearm
0.018 0.982 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.018 0.982 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.018 0.982 0.000
I86 Varicose veins of other sites
0.000 0.982 0.018
S71 Open wound of hip and thigh
0.018 0.982 0.000
S59 Other and unspecified injuries of forearm
0.018 0.982 0.000
S58 Traumatic amputation of forearm
0.018 0.982 0.000
S57 Crushing injury of forearm
0.018 0.982 0.000
S55 Injury of blood vessels at forearm level
0.018 0.982 0.000
S54 Injury of nerves at forearm level
0.018 0.982 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.018 0.982 0.000
I62.1 Nontraumatic extradural haemorrhage
0.000 0.982 0.018
S91.7 Multiple open wounds of ankle and foot
0.018 0.982 0.000
S91.2 Open wound of toe(s) with damage to nail
0.018 0.982 0.000
S91.0 Open wound of ankle
0.018 0.982 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.018 0.982 0.000
I63 Cerebral infarction
0.000 0.982 0.018
M79.5 Residual foreign body in soft tissue
0.018 0.982 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.018 0.982 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.018 0.982 0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified
0.018 0.982 0.000
S10-S19 Injuries to the neck
0.018 0.982 0.000
T65 Toxic effect of other and unspecified substances
0.018 0.982 0.000
T62 Toxic effect of other noxious substances eaten as food
0.018 0.982 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.018 0.982 0.000
T60 Toxic effect of pesticides
0.018 0.982 0.000
T59 Toxic effect of other gases, fumes and vapours
0.018 0.982 0.000
T57 Toxic effect of other inorganic substances
0.018 0.982 0.000
T56 Toxic effect of metals
0.018 0.982 0.000
T54 Toxic effect of corrosive substances
0.018 0.982 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.018 0.982 0.000
T52 Toxic effect of organic solvents
0.018 0.982 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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