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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4252129
log Bayes Factor = 0.666993
Chromosome 6   position 161,152,905  (GRCh37) Explore rs4252129 on Ensembl!
Variant rs4252129 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
0.000 0.233 0.767
I25.1 Atherosclerotic heart disease
0.000 0.240 0.760
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.243 0.757
I20-I25 Ischaemic heart diseases
0.000 0.264 0.736
I21 Acute myocardial infarction
0.000 0.290 0.710
I20 Angina pectoris
0.000 0.306 0.694
I21.9 Acute myocardial infarction, unspecified
0.000 0.319 0.681
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.349 0.651
I20.9 Angina pectoris, unspecified
0.000 0.359 0.641
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.384 0.616
I20.8 Other forms of angina pectoris
0.000 0.404 0.595
I25.2 Old myocardial infarction
0.000 0.434 0.566
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.443 0.557
I25.6 Silent myocardial ischaemia
0.000 0.450 0.550
I25.4 Coronary artery aneurysm
0.000 0.450 0.550
I25.3 Aneurysm of heart
0.000 0.450 0.550
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.450 0.550
I22 Subsequent myocardial infarction
0.000 0.467 0.533
I23 Certain current complications following acute myocardial infarction
0.000 0.472 0.528
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.491 0.509
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.491 0.509
I20.0 Unstable angina
0.000 0.505 0.495
I25.5 Ischaemic cardiomyopathy
0.000 0.507 0.493
I20.1 Angina pectoris with documented spasm
0.000 0.534 0.466
I24 Other acute ischaemic heart diseases
0.000 0.535 0.465
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.546 0.454
I21.4 Acute subendocardial myocardial infarction
0.000 0.577 0.422
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.591 0.409
I22.8 Subsequent myocardial infarction of other sites
0.000 0.618 0.382
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.618 0.382
I23.8 Other current complications following acute myocardial infarction
0.000 0.621 0.379
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.621 0.379
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.621 0.379
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.621 0.379
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.621 0.379
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.621 0.379
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.621 0.379
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.621 0.379
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.645 0.355
I24.8 Other forms of acute ischaemic heart disease
0.000 0.666 0.334
I24.1 Dressler's syndrome
0.000 0.667 0.333
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.675 0.325
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.719 0.281
Chapter IX Diseases of the circulatory system
0.000 0.914 0.086
I30-I52 Other forms of heart disease
0.000 0.917 0.083
I31 Other diseases of pericardium
0.000 0.922 0.078
I50 Heart failure
0.000 0.925 0.075
I35 Nonrheumatic aortic valve disorders
0.000 0.927 0.073
I31.3 Pericardial effusion (noninflammatory)
0.000 0.930 0.070
I05-I09 Chronic rheumatic heart diseases
0.000 0.930 0.070
I42 Cardiomyopathy
0.000 0.930 0.069
I35.0 Aortic (valve) stenosis
0.000 0.932 0.068
I31.9 Disease of pericardium, unspecified
0.000 0.932 0.068
I46 Cardiac arrest
0.000 0.934 0.066
I50.9 Heart failure, unspecified
0.000 0.935 0.065
I50.1 Left ventricular failure
0.000 0.935 0.065
I00-I02 Acute rheumatic fever
0.000 0.938 0.062
I49 Other cardiac arrhythmias
0.000 0.938 0.061
I51 Complications and ill-defined descriptions of heart disease
0.000 0.939 0.061
I33 Acute and subacute endocarditis
0.000 0.939 0.060
I42.9 Cardiomyopathy, unspecified
0.000 0.940 0.060
I08 Multiple valve diseases
0.000 0.940 0.060
I52 Other heart disorders in diseases classified elsewhere
0.000 0.940 0.059
I48 Atrial fibrillation and flutter
0.000 0.940 0.059
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.940 0.059
I41 Myocarditis in diseases classified elsewhere
0.000 0.940 0.059
I40 Acute myocarditis
0.000 0.940 0.059
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.940 0.059
I37 Pulmonary valve disorders
0.000 0.940 0.059
I36 Nonrheumatic tricuspid valve disorders
0.000 0.940 0.059
I32 Pericarditis in diseases classified elsewhere
0.000 0.940 0.059
I30 Acute pericarditis
0.000 0.940 0.059
I46.0 Cardiac arrest with successful resuscitation
0.000 0.944 0.056
I31.8 Other specified diseases of pericardium
0.000 0.944 0.056
I31.2 Haemopericardium, not elsewhere classified
0.000 0.944 0.056
I31.1 Chronic constrictive pericarditis
0.000 0.944 0.056
I31.0 Chronic adhesive pericarditis
0.000 0.944 0.056
I51.8 Other ill-defined heart diseases
0.000 0.945 0.055
I45 Other conduction disorders
0.000 0.947 0.053
I49.3 Ventricular premature depolarisation
0.000 0.947 0.053
I08.0 Disorders of both mitral and aortic valves
0.000 0.947 0.052
I35.9 Aortic valve disorder, unspecified
0.000 0.948 0.052
I35.8 Other aortic valve disorders
0.000 0.948 0.052
I42.0 Dilated cardiomyopathy
0.000 0.949 0.051
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.949 0.051
I09 Other rheumatic heart diseases
0.000 0.950 0.050
I06 Rheumatic aortic valve diseases
0.000 0.950 0.050
I05 Rheumatic mitral valve diseases
0.000 0.950 0.050
I42.8 Other cardiomyopathies
0.000 0.950 0.050
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.950 0.050
I42.6 Alcoholic cardiomyopathy
0.000 0.950 0.050
I42.5 Other restrictive cardiomyopathy
0.000 0.950 0.050
I42.4 Endocardial fibroelastosis
0.000 0.950 0.050
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.950 0.050
I42.2 Other hypertrophic cardiomyopathy
0.000 0.950 0.050
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.950 0.050
I47 Paroxysmal tachycardia
0.000 0.950 0.050
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.950 0.049
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.951 0.049
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.952 0.048
I38 Endocarditis, valve unspecified
0.000 0.952 0.048
I49.8 Other specified cardiac arrhythmias
0.000 0.952 0.047
I50.0 Congestive heart failure
0.000 0.952 0.047
I46.1 Sudden cardiac death, so described
0.000 0.953 0.047
I60-I69 Cerebrovascular diseases
0.000 0.953 0.047
I07 Rheumatic tricuspid valve diseases
0.000 0.953 0.047
I49.0 Ventricular fibrillation and flutter
0.000 0.953 0.047
I49.9 Cardiac arrhythmia, unspecified
0.000 0.955 0.045
I02 Rheumatic chorea
0.000 0.955 0.045
I01 Rheumatic fever with heart involvement
0.000 0.955 0.045
I00 Rheumatic fever without mention of heart involvement
0.000 0.955 0.045
I35.1 Aortic (valve) insufficiency
0.000 0.955 0.045
I33.0 Acute and subacute infective endocarditis
0.000 0.955 0.044
I49.2 Junctional premature depolarisation
0.000 0.956 0.044
I49.1 Atrial premature depolarisation
0.000 0.956 0.044
I51.6 Cardiovascular disease, unspecified
0.000 0.956 0.044
I51.5 Myocardial degeneration
0.000 0.956 0.044
I51.4 Myocarditis, unspecified
0.000 0.956 0.044
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.956 0.044
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.956 0.044
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.956 0.044
I51.0 Cardiac septal defect, acquired
0.000 0.956 0.044
I33.9 Acute endocarditis, unspecified
0.000 0.956 0.043
I51.9 Heart disease, unspecified
0.000 0.957 0.043
I08.9 Multiple valve disease, unspecified
0.000 0.957 0.043
I08.8 Other multiple valve diseases
0.000 0.957 0.043
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.957 0.043
I30.9 Acute pericarditis, unspecified
0.000 0.957 0.043
I30.8 Other forms of acute pericarditis
0.000 0.957 0.043
I30.1 Infective pericarditis
0.000 0.957 0.043
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.957 0.043
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.957 0.043
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.957 0.043
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.957 0.043
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.957 0.043
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.957 0.043
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.957 0.043
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.957 0.043
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.957 0.043
I37.9 Pulmonary valve disorder, unspecified
0.000 0.957 0.043
I37.8 Other pulmonary valve disorders
0.000 0.957 0.043
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.957 0.043
I37.1 Pulmonary valve insufficiency
0.000 0.957 0.043
I37.0 Pulmonary valve stenosis
0.000 0.957 0.043
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.957 0.043
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.957 0.043
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.957 0.043
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.957 0.043
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.957 0.043
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.957 0.043
I40.9 Acute myocarditis, unspecified
0.000 0.957 0.043
I40.8 Other acute myocarditis
0.000 0.957 0.043
I40.1 Isolated myocarditis
0.000 0.957 0.043
I40.0 Infective myocarditis
0.000 0.957 0.043
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.957 0.043
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.957 0.043
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.957 0.043
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.957 0.043
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.957 0.043
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.957 0.043
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.957 0.043
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.957 0.043
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.957 0.043
I48.4 Atypical atrial flutter
0.000 0.957 0.043
I48.3 Typical atrial flutter
0.000 0.957 0.043
I48.2 Chronic atrial fibrillation
0.000 0.957 0.043
I48.1 Persistent atrial fibrillation
0.000 0.957 0.043
I48.0 Paroxysmal atrial fibrillation
0.000 0.957 0.043
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.957 0.043
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.957 0.043
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.957 0.043
I46.9 Cardiac arrest, unspecified
0.000 0.957 0.042
I44 Atrioventricular and left bundle-branch block
0.000 0.957 0.043
I67 Other cerebrovascular diseases
0.000 0.959 0.041
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.959 0.041
I45.1 Other and unspecified right bundle-branch block
0.000 0.961 0.039
I45.8 Other specified conduction disorders
0.000 0.962 0.038
I45.5 Other specified heart block
0.000 0.962 0.038
I45.4 Nonspecific intraventricular block
0.000 0.962 0.038
I45.3 Trifascicular block
0.000 0.962 0.038
I45.2 Bifascicular block
0.000 0.962 0.038
I45.0 Right fascicular block
0.000 0.962 0.038
I71 Aortic aneurysm and dissection
0.000 0.962 0.038
I49.5 Sick sinus syndrome
0.000 0.962 0.038
I60 Subarachnoid haemorrhage
0.000 0.963 0.037
I74 Arterial embolism and thrombosis
0.000 0.963 0.037
I05.9 Mitral valve disease, unspecified
0.000 0.964 0.036
I05.8 Other mitral valve diseases
0.000 0.964 0.036
I05.2 Mitral stenosis with insufficiency
0.000 0.964 0.036
I05.1 Rheumatic mitral insufficiency
0.000 0.964 0.036
I05.0 Mitral stenosis
0.000 0.964 0.036
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.964 0.036
I06.8 Other rheumatic aortic valve diseases
0.000 0.964 0.036
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.964 0.036
I06.1 Rheumatic aortic insufficiency
0.000 0.964 0.036
I06.0 Rheumatic aortic stenosis
0.000 0.964 0.036
I09.9 Rheumatic heart disease, unspecified
0.000 0.964 0.036
I09.8 Other specified rheumatic heart diseases
0.000 0.964 0.036
I09.2 Chronic rheumatic pericarditis
0.000 0.964 0.036
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.964 0.036
I09.0 Rheumatic myocarditis
0.000 0.964 0.036
I10-I15 Hypertensive diseases
0.000 0.964 0.036
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.964 0.036
I47.0 Reentry ventricular arrhythmia
0.000 0.964 0.036
I28 Other diseases of pulmonary vessels
0.000 0.964 0.036
I45.9 Conduction disorder, unspecified
0.000 0.965 0.035
I61 Intracerebral haemorrhage
0.000 0.965 0.035
I27 Other pulmonary heart diseases
0.000 0.965 0.035
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.965 0.035
I67.9 Cerebrovascular disease, unspecified
0.000 0.965 0.035
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.965 0.035
I72 Other aneurysm
0.000 0.965 0.035
I67.1 Cerebral aneurysm, nonruptured
0.000 0.965 0.035
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.966 0.034
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.966 0.034
I07.9 Tricuspid valve disease, unspecified
0.000 0.966 0.034
I07.8 Other tricuspid valve diseases
0.000 0.966 0.034
I07.2 Tricuspid stenosis with insufficiency
0.000 0.966 0.034
I07.0 Tricuspid stenosis
0.000 0.966 0.034
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.966 0.034
I45.6 Preexcitation syndrome
0.000 0.966 0.034
I70 Atherosclerosis
0.000 0.966 0.034
I47.2 Ventricular tachycardia
0.000 0.967 0.033
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.968 0.032
I01.8 Other acute rheumatic heart disease
0.000 0.968 0.032
I01.2 Acute rheumatic myocarditis
0.000 0.968 0.032
I01.1 Acute rheumatic endocarditis
0.000 0.968 0.032
I01.0 Acute rheumatic pericarditis
0.000 0.968 0.032
I02.9 Rheumatic chorea without heart involvement
0.000 0.968 0.032
I02.0 Rheumatic chorea with heart involvement
0.000 0.968 0.032
I69 Sequelae of cerebrovascular disease
0.000 0.968 0.032
I77 Other disorders of arteries and arterioles
0.000 0.969 0.031
I44.1 Atrioventricular block, second degree
0.000 0.969 0.031
I07.1 Tricuspid insufficiency
0.000 0.969 0.031
I34 Nonrheumatic mitral valve disorders
0.000 0.969 0.031
I44.6 Other and unspecified fascicular block
0.000 0.969 0.031
I44.5 Left posterior fascicular block
0.000 0.969 0.031
I44.4 Left anterior fascicular block
0.000 0.969 0.031
I44.3 Other and unspecified atrioventricular block
0.000 0.969 0.031
I73 Other peripheral vascular diseases
0.000 0.969 0.031
I67.8 Other specified cerebrovascular diseases
0.000 0.969 0.031
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.969 0.031
I44.2 Atrioventricular block, complete
0.000 0.970 0.030
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.970 0.030
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.970 0.030
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.970 0.030
I67.5 Moyamoya disease
0.000 0.970 0.030
I67.4 Hypertensive encephalopathy
0.000 0.970 0.030
I67.3 Progressive vascular leukoencephalopathy
0.000 0.970 0.030
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.970 0.030
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.970 0.030
I47.1 Supraventricular tachycardia
0.000 0.970 0.030
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.970 0.029
I49.4 Other and unspecified premature depolarisation
0.000 0.971 0.029
I44.0 Atrioventricular block, first degree
0.000 0.972 0.028
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.972 0.028
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.972 0.027
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.972 0.027
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.972 0.027
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.972 0.027
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.972 0.027
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.972 0.027
I71.0 Dissection of aorta [any part]
0.000 0.972 0.027
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.973 0.027
I62 Other nontraumatic intracranial haemorrhage
0.000 0.973 0.027
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.973 0.027
I78 Diseases of capillaries
0.000 0.973 0.027
I60.8 Other subarachnoid haemorrhage
0.000 0.973 0.027
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.973 0.027
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.973 0.027
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.973 0.027
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.973 0.027
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.973 0.027
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.973 0.027
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.973 0.027
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.973 0.027
I99 Other and unspecified disorders of circulatory system
0.000 0.973 0.026
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.973 0.026
I74.8 Embolism and thrombosis of other arteries
0.000 0.973 0.026
I74.5 Embolism and thrombosis of iliac artery
0.000 0.973 0.026
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.973 0.026
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.973 0.026
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.973 0.026
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.973 0.026
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.973 0.026
I15 Secondary hypertension
0.000 0.974 0.026
I13 Hypertensive heart and renal disease
0.000 0.974 0.026
I11 Hypertensive heart disease
0.000 0.974 0.026
I27.2 Other secondary pulmonary hypertension
0.000 0.974 0.026
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.974 0.026
I28.8 Other specified diseases of pulmonary vessels
0.000 0.974 0.026
I28.1 Aneurysm of pulmonary artery
0.000 0.974 0.026
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.974 0.026
I61.8 Other intracerebral haemorrhage
0.000 0.974 0.025
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.974 0.025
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.974 0.025
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.974 0.025
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.974 0.025
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.974 0.025
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.974 0.025
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.974 0.025
I27.9 Pulmonary heart disease, unspecified
0.000 0.974 0.025
I27.8 Other specified pulmonary heart diseases
0.000 0.974 0.025
I27.1 Kyphoscoliotic heart disease
0.000 0.974 0.025
I72.9 Aneurysm of unspecified site
0.000 0.975 0.025
I72.8 Aneurysm of other specified arteries
0.000 0.975 0.025
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.975 0.025
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.975 0.025
I72.4 Aneurysm of artery of lower extremity
0.000 0.975 0.025
I72.3 Aneurysm of iliac artery
0.000 0.975 0.025
I72.2 Aneurysm of renal artery
0.000 0.975 0.025
I72.1 Aneurysm of artery of upper extremity
0.000 0.975 0.025
I72.0 Aneurysm of carotid artery
0.000 0.975 0.025
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.975 0.025
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.975 0.025
I79.1 Aortitis in diseases classified elsewhere
0.000 0.975 0.025
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.975 0.025
I73.0 Raynaud's syndrome
0.000 0.975 0.025
I67.2 Cerebral atherosclerosis
0.000 0.975 0.025
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.975 0.025
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.975 0.025
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.975 0.025
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.975 0.025
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.975 0.025
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.975 0.025
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.975 0.025
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.975 0.025
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.975 0.025
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.975 0.025
I68.0 Cerebral amyloid angiopathy
0.000 0.975 0.025
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.975 0.024
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.975 0.024
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.975 0.024
I65.1 Occlusion and stenosis of basilar artery
0.000 0.975 0.024
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.975 0.024
I70.9 Generalised and unspecified atherosclerosis
0.000 0.976 0.024
I70.8 Atherosclerosis of other arteries
0.000 0.976 0.024
I70.1 Atherosclerosis of renal artery
0.000 0.976 0.024
I70.0 Atherosclerosis of aorta
0.000 0.976 0.024
I69.3 Sequelae of cerebral infarction
0.000 0.976 0.024
I65.2 Occlusion and stenosis of carotid artery
0.000 0.976 0.024
I26 Pulmonary embolism
0.000 0.976 0.024
I27.0 Primary pulmonary hypertension
0.000 0.976 0.024
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.976 0.024
I12 Hypertensive renal disease
0.000 0.976 0.024
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.977 0.023
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.977 0.023
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.977 0.023
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.977 0.023
I77.8 Other specified disorders of arteries and arterioles
0.000 0.977 0.022
I77.6 Arteritis, unspecified
0.000 0.977 0.022
I77.5 Necrosis of artery
0.000 0.977 0.022
I77.4 Coeliac artery compression syndrome
0.000 0.977 0.022
I77.3 Arterial fibromuscular dysplasia
0.000 0.977 0.022
I77.2 Rupture of artery
0.000 0.977 0.022
I77.0 Arteriovenous fistula, acquired
0.000 0.977 0.022
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.978 0.022
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.978 0.022
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.978 0.022
I73.8 Other specified peripheral vascular diseases
0.000 0.978 0.022
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.978 0.022
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.978 0.022
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.978 0.022
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.978 0.021
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.978 0.021
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.978 0.021
I98.0 Cardiovascular syphilis
0.000 0.978 0.021
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.978 0.021
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.978 0.021
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.978 0.021
I97.1 Other functional disturbances following cardiac surgery
0.000 0.978 0.021
I97.0 Postcardiotomy syndrome
0.000 0.978 0.021
K83.1 Obstruction of bile duct
0.021 0.979 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.000 0.980 0.020
I62.1 Nontraumatic extradural haemorrhage
0.000 0.980 0.020
I78.9 Disease of capillaries, unspecified
0.000 0.980 0.019
I78.8 Other diseases of capillaries
0.000 0.980 0.019
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.980 0.019
I51.7 Cardiomegaly
0.000 0.981 0.019
I63 Cerebral infarction
0.000 0.981 0.019
I44.7 Left bundle-branch block, unspecified
0.000 0.981 0.019
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.981 0.019
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.981 0.019
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.981 0.019
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.981 0.019
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.981 0.019
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.981 0.019
I15.9 Seconday hypertension, unspecified
0.000 0.981 0.019
I15.8 Other secondary hypertension
0.000 0.981 0.019
I15.2 Hypertension secondary to endocrine disorders
0.000 0.981 0.019
I15.1 Hypertension secondary to other renal disorders
0.000 0.981 0.019
I15.0 Renovascular hypertension
0.000 0.981 0.019
K83 Other diseases of biliary tract
0.019 0.981 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.982 0.017
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.982 0.017
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.982 0.017
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.982 0.017
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.982 0.017
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.982 0.017
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.982 0.017
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.982 0.017
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.982 0.017
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.982 0.017
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.017 0.983 0.000
I12.9 Hypertensive renal disease without renal failure
0.000 0.983 0.017
Z51.1 Chemotherapy session for neoplasm
0.000 0.983 0.017
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.983 0.017
K82 Other diseases of gallbladder
0.017 0.983 0.000
I77.1 Stricture of artery
0.000 0.983 0.017
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.983 0.016
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.001 0.984 0.016
I78.1 Naevus, nonneoplastic
0.000 0.984 0.016
D12.6 Colon, unspecified
0.000 0.984 0.016
K86 Other diseases of pancreas
0.016 0.984 0.000
K82.8 Other specified diseases of gallbladder
0.016 0.984 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.985 0.015
I95 Hypotension
0.000 0.985 0.015
K83.8 Other specified diseases of biliary tract
0.015 0.985 0.000
I34.1 Mitral (valve) prolapse
0.001 0.985 0.014
K82.4 Cholesterolosis of gallbladder
0.015 0.985 0.000
I12.0 Hypertensive renal disease with renal failure
0.000 0.985 0.014
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.986 0.014
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.000 0.986 0.014
K80 Cholelithiasis
0.014 0.986 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.986 0.014
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.986 0.014
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.986 0.014
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.986 0.014
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.986 0.014
K83.9 Disease of biliary tract, unspecified
0.014 0.986 0.000
K83.5 Biliary cyst
0.014 0.986 0.000
K83.4 Spasm of sphincter of Oddi
0.014 0.986 0.000
K83.3 Fistula of bile duct
0.014 0.986 0.000
K83.2 Perforation of bile duct
0.014 0.986 0.000
K86.2 Cyst of pancreas
0.014 0.986 0.000
D12.5 Sigmoid colon
0.000 0.986 0.014
K83.0 Cholangitis
0.013 0.986 0.000
D12.8 Rectum
0.000 0.987 0.013
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.987 0.013
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.013 0.987 0.000
K81 Cholecystitis
0.013 0.987 0.000
K85 Acute pancreatitis
0.012 0.987 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.012 0.987 0.000
K86.3 Pseudocyst of pancreas
0.012 0.988 0.000
K82.9 Disease of gallbladder, unspecified
0.012 0.988 0.000
K82.3 Fistula of gallbladder
0.012 0.988 0.000
K82.2 Perforation of gallbladder
0.012 0.988 0.000
K82.1 Hydrops of gallbladder
0.012 0.988 0.000
K82.0 Obstruction of gallbladder
0.012 0.988 0.000
I73.9 Peripheral vascular disease, unspecified
0.000 0.988 0.012
D12.2 Ascending colon
0.000 0.988 0.012
K80.2 Calculus of gallbladder without cholecystitis
0.012 0.988 0.000
K86.1 Other chronic pancreatitis
0.011 0.988 0.000
K86.9 Disease of pancreas, unspecified
0.011 0.989 0.000
I34.0 Mitral (valve) insufficiency
0.001 0.989 0.011
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.989 0.011
I95.2 Hypotension due to drugs
0.000 0.989 0.011
I95.8 Other hypotension
0.000 0.989 0.011
I95.0 Idiopathic hypotension
0.000 0.989 0.011
I63.9 Cerebral infarction, unspecified
0.000 0.989 0.011
K80.0 Calculus of gallbladder with acute cholecystitis
0.011 0.989 0.000
I63.8 Other cerebral infarction
0.000 0.989 0.010
K80.1 Calculus of gallbladder with other cholecystitis
0.011 0.989 0.000
K81.9 Cholecystitis, unspecified
0.011 0.989 0.000
D12.9 Anus and anal canal
0.000 0.990 0.010
D12.1 Appendix
0.000 0.990 0.010
K80.3 Calculus of bile duct with cholangitis
0.010 0.990 0.000
K80.8 Other cholelithiasis
0.010 0.990 0.000
K80.4 Calculus of bile duct with cholecystitis
0.010 0.990 0.000
D12.4 Descending colon
0.000 0.990 0.010
D12.3 Transverse colon
0.000 0.990 0.010
I88 Nonspecific lymphadenitis
0.000 0.990 0.009
I87 Other disorders of veins
0.000 0.990 0.009
I81 Portal vein thrombosis
0.000 0.990 0.009
K86.8 Other specified diseases of pancreas
0.009 0.990 0.000
K87.1 Disorders of pancreas in diseases classified elsewhere
0.009 0.991 0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.009 0.991 0.000
K81.8 Other cholecystitis
0.009 0.991 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.009 0.991 0.000
I84 Haemorrhoids
0.000 0.991 0.009
K85.8 Other acute pancreatitis
0.009 0.991 0.000
K85.3 Drug-induced acute pancreatitis
0.009 0.991 0.000
K85.2 Alcohol-induced acute pancreatitis
0.009 0.991 0.000
K85.1 Biliary acute pancreatitis
0.009 0.991 0.000
K85.0 Idiopathic acute pancreatitis
0.009 0.991 0.000
I82 Other venous embolism and thrombosis
0.000 0.991 0.009
I84.1 Internal haemorrhoids with other complications
0.000 0.991 0.009
I86 Varicose veins of other sites
0.000 0.991 0.009
D12.0 Caecum
0.000 0.991 0.009
K85.9 Acute pancreatitis, unspecified
0.009 0.991 0.000
K81.0 Acute cholecystitis
0.009 0.991 0.000
D12.7 Rectosigmoid junction
0.000 0.991 0.009
I85 Oesophageal varices
0.000 0.991 0.008
K81.1 Chronic cholecystitis
0.008 0.992 0.000
I84.4 External haemorrhoids with other complications
0.000 0.992 0.008
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.008 0.992 0.000
I84.2 Internal haemorrhoids without complication
0.000 0.992 0.008
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.992 0.007
Z09.0 Follow-up examination after surgery for other conditions
0.000 0.992 0.008
I10 Essential (primary) hypertension
0.000 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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