TreeWAS – Variant ID: rs427576

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S83.2 Tear of meniscus, current	0.070	0.930	0.000
I85.9 Oesophageal varices without bleeding	0.058	0.942	0.000
I85.0 Oesophageal varices with bleeding	0.057	0.943	0.000
I85 Oesophageal varices	0.054	0.946	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.018	0.982	0.000
B37.0 Candidal stomatitis	0.016	0.984	0.000
S83.3 Tear of articular cartilage of knee, current	0.015	0.985	0.000
S83.0 Dislocation of patella	0.014	0.986	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.014	0.986	0.000
S83.1 Dislocation of knee	0.013	0.987	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.013	0.987	0.000
E83.3 Disorders of phosphorus metabolism	0.012	0.988	0.000
S83.7 Injury to multiple structures of knee	0.011	0.988	0.000
G60.0 Hereditary motor and sensory neuropathy	0.012	0.988	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.011	0.989	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.990	0.010
Z95.0 Presence of cardiac pacemaker	0.000	0.991	0.009
E83 Disorders of mineral metabolism	0.008	0.992	0.000
E89.2 Postprocedural hypoparathyroidism	0.008	0.992	0.000
E11.4 With neurological complications	0.008	0.992	0.000
E80.4 Gilbert's syndrome	0.008	0.992	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.008	0.992	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.008	0.992	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.008	0.992	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.008	0.992	0.000
B37.9 Candidiasis, unspecified	0.008	0.992	0.000
E83.4 Disorders of magnesium metabolism	0.008	0.992	0.000
E85 Amyloidosis	0.007	0.993	0.000
E70-E90 Metabolic disorders	0.007	0.993	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.007	0.993	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.993	0.007
E85.4 Organ-limited amyloidosis	0.007	0.993	0.000
E80.2 Other porphyria	0.007	0.993	0.000
E11 Non-insulin-dependent diabetes mellitus	0.007	0.993	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.007	0.993	0.000
G60 Hereditary and idiopathic neuropathy	0.006	0.993	0.000
E10.3 With ophthalmic complications	0.007	0.993	0.000
B37 Candidiasis	0.006	0.993	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.994	0.006
E74 Other disorders of carbohydrate metabolism	0.006	0.994	0.000
E85.9 Amyloidosis, unspecified	0.006	0.994	0.000
E11.8 With unspecified complications	0.006	0.994	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.006	0.994	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.006	0.994	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.994	0.006
E83.8 Other disorders of mineral metabolism	0.006	0.994	0.000
E83.2 Disorders of zinc metabolism	0.006	0.994	0.000
E83.0 Disorders of copper metabolism	0.006	0.994	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.006	0.994	0.000
E11.3 With ophthalmic complications	0.006	0.994	0.000
E80.1 Porphyria cutanea tarda	0.006	0.994	0.000
E85.8 Other amyloidosis	0.006	0.994	0.000
E79 Disorders of purine and pyrimidine metabolism	0.006	0.994	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.006	0.994	0.000
E11.2 With renal complications	0.006	0.994	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.006	0.994	0.000
E80.5 Crigler-Najjar syndrome	0.006	0.994	0.000
E80.3 Defects of catalase and peroxydase	0.006	0.994	0.000
E80.0 Hereditary erythropoietic porphyria	0.006	0.994	0.000
E73 Lactose intolerance	0.006	0.994	0.000
E72 Other disorders of amino-acid metabolism	0.006	0.994	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.006	0.994	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.006	0.994	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.006	0.994	0.000
E84 Cystic fibrosis	0.006	0.994	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.005	0.994	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.006	0.994	0.000
E10.2 With renal complications	0.006	0.994	0.000
E78.4 Other hyperlipidaemia	0.006	0.994	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.005	0.994	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.005	0.994	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.005	0.994	0.000
E85.3 Secondary systemic amyloidosis	0.005	0.994	0.000
E77 Disorders of glycoprotein metabolism	0.005	0.994	0.000
E76 Disorders of glycosaminoglycan metabolism	0.005	0.994	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.005	0.994	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.005	0.994	0.000
B37.1 Pulmonary candidiasis	0.005	0.994	0.000
E87.6 Hypokalaemia	0.005	0.995	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.995	0.005
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.995	0.005
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.995	0.005
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.995	0.005
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.995	0.005
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.995	0.005
E61.1 Iron deficiency	0.005	0.995	0.000
E70 Disorders of aromatic amino-acid metabolism	0.005	0.995	0.000
E74.0 Glycogen storage disease	0.005	0.995	0.000
E11.1 With ketoacidosis	0.005	0.995	0.000
E10 Insulin-dependent diabetes mellitus	0.005	0.995	0.000
E11.0 With coma	0.005	0.995	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.005	0.995	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.005	0.995	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.005	0.995	0.000
E11.7 With multiple complications	0.005	0.995	0.000
E78.6 Lipoprotein deficiency	0.005	0.995	0.000
E78.1 Pure hyperglyceridaemia	0.005	0.995	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.005	0.995	0.000
G60.3 Idiopathic progressive neuropathy	0.005	0.995	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.005	0.995	0.000
G60.1 Refsum's disease	0.005	0.995	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.005	0.995	0.000
E89.5 Postprocedural testicular hypofunction	0.005	0.995	0.000
B37.6 Candidal endocarditis	0.005	0.995	0.000
B37.5 Candidal meningitis	0.005	0.995	0.000
E80.6 Other disorders of bilirubin metabolism	0.005	0.995	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.005	0.995	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.005	0.995	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.005	0.995	0.000
E74.2 Disorders of galactose metabolism	0.005	0.995	0.000
E74.1 Disorders of fructose metabolism	0.005	0.995	0.000
E78.3 Hyperchylomicronaemia	0.005	0.995	0.000
E10-E14 Diabetes mellitus	0.005	0.995	0.000
M80 Osteoporosis with pathological fracture	0.000	0.995	0.005
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.995	0.005
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.005	0.995	0.000
E10.1 With ketoacidosis	0.005	0.995	0.000
E73.9 Lactose intolerance, unspecified	0.005	0.995	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.005	0.995	0.000
E78.5 Hyperlipidaemia, unspecified	0.005	0.995	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.005	0.995	0.000
E78.2 Mixed hyperlipidaemia	0.005	0.995	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.995	0.000
E72.0 Disorders of amino-acid transport	0.004	0.995	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.004	0.995	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.004	0.995	0.000
E79.1 Lesch-Nyhan syndrome	0.004	0.995	0.000
E11.6 With other specified complications	0.004	0.995	0.000
G61.8 Other inflammatory polyneuropathies	0.004	0.995	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.995	0.004
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.996	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.996	0.000
E72.5 Disorders of glycine metabolism	0.004	0.996	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.996	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.996	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.004	0.996	0.000
E73.1 Secondary lactase deficiency	0.004	0.996	0.000
E73.0 Congenital lactase deficiency	0.004	0.996	0.000
E84.9 Cystic fibrosis, unspecified	0.004	0.996	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.996	0.004
E84.8 Cystic fibrosis with other manifestations	0.004	0.996	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.996	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.996	0.000
S32.50 Fracture of pubis (closed)	0.004	0.996	0.000
E10.8 With unspecified complications	0.004	0.996	0.000
M05 Seropositive rheumatoid arthritis	0.004	0.996	0.000
E83.5 Disorders of calcium metabolism	0.004	0.996	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.996	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.996	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.996	0.000
E71.0 Maple-syrup-urine disease	0.004	0.996	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.996	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.996	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.996	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.996	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.996	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.996	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.996	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.996	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.996	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.996	0.000
G61 Inflammatory polyneuropathy	0.004	0.996	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
E10.7 With multiple complications	0.004	0.996	0.000
E11.5 With peripheral circulatory complications	0.004	0.996	0.000
E89.4 Postprocedural ovarian failure	0.004	0.996	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.996	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.996	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.996	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.996	0.000
E70.0 Classical phenylketonuria	0.004	0.996	0.000
G62 Other polyneuropathies	0.004	0.996	0.000
K50.8 Other Crohn's disease	0.004	0.996	0.000
E10.0 With coma	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.996	0.004
E75.6 Lipid storage disorder, unspecified	0.004	0.996	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.996	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.996	0.000
E75.1 Other gangliosidosis	0.004	0.996	0.000
E75.0 GM2 gangliosidosis	0.004	0.996	0.000
E70.3 Albinism	0.004	0.996	0.000
G62.8 Other specified polyneuropathies	0.004	0.996	0.000
B37.7 Candidal septicaemia	0.004	0.996	0.000
N13.4 Hydroureter	0.000	0.996	0.004
G63 Polyneuropathy in diseases classified elsewhere	0.004	0.996	0.000
E75.2 Other sphingolipidosis	0.004	0.996	0.000
K51.2 Ulcerative (chronic) proctitis	0.004	0.996	0.000
E61 Deficiency of other nutrient elements	0.004	0.996	0.000
E10.4 With neurological complications	0.004	0.996	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.996	0.004
E75.5 Other lipid storage disorders	0.004	0.996	0.000
E88 Other metabolic disorders	0.004	0.996	0.000
M05.1 Rheumatoid lung disease	0.004	0.996	0.000
B37.2 Candidiasis of skin and nail	0.003	0.996	0.000
E12 Malnutrition-related diabetes mellitus	0.004	0.996	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.996	0.004
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.996	0.004
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.996	0.004
G62.9 Polyneuropathy, unspecified	0.004	0.996	0.000
G64 Other disorders of peripheral nervous system	0.004	0.996	0.000
N13.8 Other obstructive and reflux uropathy	0.000	0.996	0.004
K50 Crohn's disease [regional enteritis]	0.004	0.996	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.003
G60.8 Other hereditary and idiopathic neuropathies	0.003	0.996	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.996	0.004
E89.3 Postprocedural hypopituitarism	0.003	0.996	0.000
K50.9 Crohn's disease, unspecified	0.004	0.996	0.000
N13 Obstructive and reflux uropathy	0.000	0.996	0.004
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.996	0.003
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
E88.8 Other specified metabolic disorders	0.003	0.997	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.003	0.997	0.000
M05.0 Felty's syndrome	0.003	0.997	0.000
N13.6 Pyonephrosis	0.000	0.997	0.003
G61.1 Serum neuropathy	0.003	0.997	0.000
M05.8 Other seropositive rheumatoid arthritis	0.003	0.997	0.000
B37.3 Candidiasis of vulva and vagina	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
M06.0 Seronegative rheumatoid arthritis	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.997	0.003
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.003	0.997	0.000
S32.5 Fracture of pubis	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.003	0.997	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
G62.2 Polyneuropathy due to other toxic agents	0.003	0.997	0.000
M05.2 Rheumatoid vasculitis	0.003	0.997	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
B37.4 Candidiasis of other urogenital sites	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.003	0.997	0.000
D37.4 Colon	0.000	0.997	0.003
G61.0 Guillain-Barre syndrome	0.003	0.997	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.003	0.997	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.003	0.997	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.003	0.997	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.003	0.997	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.003	0.997	0.000
G63.1 Polyneuropathy in neoplastic disease	0.003	0.997	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.003	0.997	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
G62.1 Alcoholic polyneuropathy	0.003	0.997	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.997	0.003
E50-E64 Other nutritional deficiencies	0.003	0.997	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.997	0.003
M05.18 Rheumatoid lung disease (Other)	0.003	0.997	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.003	0.997	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.003	0.997	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.003	0.997	0.000
M05.14 Rheumatoid lung disease (Hand)	0.003	0.997	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.003	0.997	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.003	0.997	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.003	0.997	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.003	0.997	0.000
E12.9 Without complications	0.003	0.997	0.000
E12.8 With unspecified complications	0.003	0.997	0.000
E12.7 With multiple complications	0.003	0.997	0.000
E12.6 With other specified complications	0.003	0.997	0.000
E12.5 With peripheral circulatory complications	0.003	0.997	0.000
E12.4 With neurological complications	0.003	0.997	0.000
E12.3 With ophthalmic complications	0.003	0.997	0.000
E12.2 With renal complications	0.003	0.997	0.000
E12.1 With ketoacidosis	0.003	0.997	0.000
E12.0 With coma	0.003	0.997	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.997	0.003
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.997	0.003
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.997	0.003
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.997	0.003
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.997	0.003
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.003
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.997	0.003
O21.0 Mild hyperemesis gravidarum	0.003	0.997	0.000
R40.0 Somnolence	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.003	0.997	0.000
O36.8 Maternal care for other specified foetal problems	0.003	0.997	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.003	0.997	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
E88.2 Lipomatosis, not elsewhere classified	0.003	0.997	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.003	0.997	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.003	0.997	0.000
H92.0 Otalgia	0.003	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
S60.8 Other superficial injuries of wrist and hand	0.003	0.997	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.003	0.997	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.003	0.997	0.000
E13 Other specified diabetes mellitus	0.003	0.997	0.000
E51 Thiamine deficiency	0.003	0.997	0.000
E88.9 Metabolic disorder, unspecified	0.003	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
E88.3 Tumour lysis syndrome	0.003	0.997	0.000
Z32.1 Pregnancy confirmed	0.000	0.997	0.003
M05.09 Felty's syndrome (Site unspecified)	0.002	0.997	0.000
M05.08 Felty's syndrome (Other)	0.002	0.997	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.002	0.997	0.000
M05.06 Felty's syndrome (Lower leg)	0.002	0.997	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.002	0.997	0.000
M05.04 Felty's syndrome (Hand)	0.002	0.997	0.000
M05.03 Felty's syndrome (Forearm)	0.002	0.997	0.000
M05.02 Felty's syndrome (Upper arm)	0.002	0.997	0.000
M05.01 Felty's syndrome (Shoulder region)	0.002	0.997	0.000
M05.00 Felty's syndrome (Multiple sites)	0.002	0.997	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.002	0.997	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.002	0.997	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.002	0.997	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.002	0.997	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.002	0.997	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.002	0.997	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.002	0.997	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.002	0.997	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.002	0.997	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.002	0.997	0.000
K50.0 Crohn's disease of small intestine	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.997	0.003
M05.88 Other seropositive rheumatoid arthritis (Other)	0.002	0.997	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.002	0.997	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.002	0.997	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.002	0.997	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.002	0.997	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.002	0.997	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.002	0.997	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.002	0.997	0.000
E51.2 Wernicke's encephalopathy	0.003	0.997	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.002	0.997	0.000
E61.2 Magnesium deficiency	0.002	0.997	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.002	0.997	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.003	0.997	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.003	0.997	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.003	0.997	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.997	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
S32.51 Fracture of pubis (open)	0.002	0.997	0.000
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
E54 Ascorbic acid deficiency	0.003	0.997	0.000
M05.28 Rheumatoid vasculitis (Other)	0.002	0.997	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.002	0.997	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.002	0.997	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.002	0.997	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.002	0.997	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.002	0.997	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.002	0.997	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.002	0.997	0.000
L40.9 Psoriasis, unspecified	0.003	0.997	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.002	0.997	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.003	0.997	0.000
E78.8 Other disorders of lipoprotein metabolism	0.002	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.002	0.998	0.000
E63 Other nutritional deficiencies	0.002	0.998	0.000
E50 Vitamin A deficiency	0.002	0.998	0.000
E60 Dietary zinc deficiency	0.002	0.998	0.000
E59 Dietary selenium deficiency	0.002	0.998	0.000
E52 Niacin deficiency [pellagra]	0.002	0.998	0.000
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
O42 Premature rupture of membranes	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.002	0.998	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.002	0.998	0.000
E56 Other vitamin deficiencies	0.002	0.998	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.002	0.998	0.000
R30.0 Dysuria	0.000	0.998	0.002
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.998	0.000
E51.9 Thiamine deficiency, unspecified	0.002	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.998	0.000
E51.1 Beriberi	0.002	0.998	0.000
L40.0 Psoriasis vulgaris	0.002	0.998	0.000
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
S32.3 Fracture of ilium	0.002	0.998	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.998	0.002
D39.1 Ovary	0.002	0.998	0.000
N17.0 Acute renal failure with tubular necrosis	0.000	0.998	0.002
B35-B49 Mycoses	0.002	0.998	0.000
N02.9 Unspecified	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.002	0.998	0.000
B35 Dermatophytosis	0.002	0.998	0.000
B35.1 Tinea unguium	0.002	0.998	0.000
E58 Dietary calcium deficiency	0.002	0.998	0.000
G62.0 Drug-induced polyneuropathy	0.002	0.998	0.000
N13.3 Other and unspecified hydronephrosis	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
E13.3 With ophthalmic complications	0.002	0.998	0.000
H27.8 Other specified disorders of lens	0.000	0.998	0.002
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.002
L40 Psoriasis	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
E55 Vitamin D deficiency	0.002	0.998	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.002	0.998	0.000
L40.1 Generalised pustular psoriasis	0.002	0.998	0.000
B36 Other superficial mycoses	0.002	0.998	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.002	0.998	0.000
C18.0 Caecum	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
Z92.8 Personal history of other medical treatment	0.000	0.998	0.002
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations