TreeWAS – Variant ID: rs4282054

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H25.8 Other senile cataract	0.000	0.642	0.358
H25 Senile cataract	0.000	0.658	0.342
F31 Bipolar affective disorder	0.000	0.658	0.342
H26.9 Cataract, unspecified	0.000	0.666	0.334
H25.1 Senile nuclear cataract	0.000	0.667	0.333
H26 Other cataract	0.000	0.670	0.330
H25-H28 Disorders of lens	0.000	0.672	0.328
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.673	0.327
F31.9 Bipolar affective disorder, unspecified	0.000	0.680	0.320
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.683	0.317
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.687	0.313
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.688	0.312
F31.7 Bipolar affective disorder, currently in remission	0.000	0.705	0.295
H26.8 Other specified cataract	0.000	0.716	0.284
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.723	0.277
H26.4 After-cataract	0.000	0.733	0.267
H26.3 Drug-induced cataract	0.000	0.737	0.263
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.741	0.259
H25.2 Senile cataract, morgagnian type	0.000	0.748	0.252
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.000	0.750	0.250
F31.8 Other bipolar affective disorders	0.000	0.752	0.247
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.758	0.242
H26.0 Infantile, juvenile and presenile cataract	0.000	0.761	0.239
H28.0 Diabetic cataract	0.000	0.806	0.194
H26.2 Complicated cataract	0.000	0.807	0.193
H28.8 Other disorders of lens in diseases classified elsewhere	0.000	0.821	0.179
H28.2 Cataract in other diseases classified elsewhere	0.000	0.821	0.179
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.000	0.821	0.179
H27 Other disorders of lens	0.000	0.822	0.178
H27.9 Disorder of lens, unspecified	0.000	0.872	0.128
H27.0 Aphakia	0.000	0.875	0.125
H25.9 Senile cataract, unspecified	0.000	0.880	0.120
H27.1 Dislocation of lens	0.000	0.891	0.108
H26.1 Traumatic cataract	0.001	0.892	0.107
H27.8 Other specified disorders of lens	0.000	0.895	0.105
T81.3 Disruption of operation wound, not elsewhere classified	0.076	0.924	0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.930	0.070
Z94.8 Other transplanted organ and tissue status	0.000	0.951	0.049
H25.0 Senile incipient cataract	0.000	0.954	0.046
Z94 Transplanted organ and tissue status	0.000	0.967	0.033
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.030	0.970	0.000
Z94.0 Kidney transplant status	0.000	0.971	0.029
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.027	0.973	0.000
Z94.2 Lung transplant status	0.000	0.973	0.027
M21.0 Valgus deformity, not elsewhere classified	0.026	0.974	0.000
Z94.6 Bone transplant status	0.000	0.974	0.026
Z94.5 Skin transplant status	0.000	0.974	0.026
Z94.1 Heart transplant status	0.000	0.975	0.025
Z94.4 Liver transplant status	0.000	0.976	0.024
Z94.3 Heart and lungs transplant status	0.000	0.976	0.024
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.977	0.023
Z96.6 Presence of orthopaedic joint implants	0.023	0.977	0.000
S32.50 Fracture of pubis (closed)	0.022	0.978	0.000
S32.40 Fracture of acetabulum (closed)	0.022	0.978	0.000
S32.5 Fracture of pubis	0.021	0.979	0.000
S32.4 Fracture of acetabulum	0.021	0.979	0.000
S32 Fracture of lumbar spine and pelvis	0.021	0.979	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.019	0.981	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.019	0.981	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.019	0.981	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.019	0.981	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.019	0.981	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.019	0.981	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.019	0.981	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.019	0.981	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.981	0.019
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.018	0.982	0.000
Z96.7 Presence of other bone and tendon implants	0.018	0.982	0.000
S32.3 Fracture of ilium	0.017	0.982	0.000
F30-F39 Mood [affective] disorders	0.000	0.983	0.017
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.016	0.984	0.000
Z96 Presence of other functional implants	0.016	0.984	0.000
S32.1 Fracture of sacrum	0.015	0.984	0.000
S32.51 Fracture of pubis (open)	0.015	0.984	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.015	0.985	0.000
S32.30 Fracture of ilium (closed)	0.015	0.985	0.000
S32.41 Fracture of acetabulum (open)	0.015	0.985	0.000
Z96.8 Presence of other specified functional implants	0.015	0.985	0.000
Z36 Antenatal screening	0.015	0.985	0.000
S32.2 Fracture of coccyx	0.015	0.985	0.000
S32.0 Fracture of lumbar vertebra	0.015	0.985	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.015	0.985	0.000
F34 Persistent mood [affective] disorders	0.000	0.986	0.014
Z36.8 Other antenatal screening	0.014	0.986	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.014	0.986	0.000
Y60.0 During surgical operation	0.000	0.987	0.013
Z36.1 Antenatal screening for raised alphafetoprotein level	0.013	0.987	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.013	0.987	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.013	0.987	0.000
S32.31 Fracture of ilium (open)	0.013	0.987	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.013	0.987	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.987	0.013
S32.10 Fracture of sacrum (closed)	0.012	0.988	0.000
F34.1 Dysthymia	0.000	0.988	0.012
F38 Other mood [affective] disorders	0.000	0.988	0.011
Z96.5 Presence of tooth-root and mandibular implants	0.011	0.988	0.000
Z96.9 Presence of functional implant, unspecified	0.011	0.989	0.000
S32.11 Fracture of sacrum (open)	0.011	0.989	0.000
Z36.5 Antenatal screening for isoimmunisation	0.011	0.989	0.000
S32.21 Fracture of coccyx (open)	0.011	0.989	0.000
S32.20 Fracture of coccyx (closed)	0.011	0.989	0.000
F34.0 Cyclothymia	0.000	0.989	0.011
S32.01 Fracture of lumbar vertebra (open)	0.011	0.989	0.000
Z96.3 Presence of artificial larynx	0.011	0.989	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.989	0.011
S32.00 Fracture of lumbar vertebra (closed)	0.011	0.989	0.000
Z94.7 Corneal transplant status	0.000	0.989	0.010
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.990	0.010
F34.8 Other persistent mood [affective] disorders	0.000	0.990	0.010
Z96.4 Presence of endocrine implants	0.010	0.990	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.010	0.990	0.000
F39 Unspecified mood [affective] disorder	0.000	0.990	0.009
I08.0 Disorders of both mitral and aortic valves	0.009	0.991	0.000
F30 Manic episode	0.000	0.991	0.009
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.991	0.009
F38.8 Other specified mood [affective] disorders	0.000	0.991	0.008
F38.1 Other recurrent mood [affective] disorders	0.000	0.991	0.008
Z96.2 Presence of otological and audiological implants	0.008	0.991	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.992	0.008
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.008	0.992	0.000
Z96.0 Presence of urogenital implants	0.008	0.992	0.000
F38.0 Other single mood [affective] disorders	0.000	0.992	0.007
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.008	0.992	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.007	0.993	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.007	0.993	0.000
M18 Arthrosis of first carpometacarpal joint	0.007	0.993	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.007	0.993	0.000
I08 Multiple valve diseases	0.007	0.993	0.000
F30.8 Other manic episodes	0.000	0.993	0.006
F30.0 Hypomania	0.000	0.994	0.006
O63.1 Prolonged second stage (of labour)	0.006	0.994	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.006	0.994	0.000
D09.0 Bladder	0.000	0.994	0.006
F30.2 Mania with psychotic symptoms	0.000	0.994	0.006
W21.9 Unspecified place	0.000	0.994	0.006
F30.9 Manic episode, unspecified	0.000	0.994	0.006
F32 Depressive episode	0.000	0.994	0.006
I08.1 Disorders of both mitral and tricuspid valves	0.006	0.994	0.000
D43.0 Brain, supratentorial	0.000	0.994	0.006
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.005	0.995	0.000
F30.1 Mania without psychotic symptoms	0.000	0.995	0.005
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.995	0.005
D68.8 Other specified coagulation defects	0.000	0.995	0.005
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.005	0.995	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.005	0.995	0.000
R17 Unspecified jaundice	0.000	0.995	0.005
C55 Malignant neoplasm of uterus, part unspecified	0.005	0.995	0.000
I08.8 Other multiple valve diseases	0.005	0.995	0.000
I08.9 Multiple valve disease, unspecified	0.005	0.995	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.005	0.995	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
D43.2 Brain, unspecified	0.000	0.995	0.005
Z93.3 Colostomy status	0.005	0.995	0.000
D37.5 Rectum	0.000	0.995	0.005
D43.1 Brain, infratentorial	0.000	0.995	0.004
D48.1 Connective and other soft tissue	0.000	0.995	0.005
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.996	0.004
H47.3 Other disorders of optic disk	0.000	0.996	0.004
D41.4 Bladder	0.000	0.996	0.004
F32.1 Moderate depressive episode	0.000	0.996	0.004
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.004	0.996	0.000
F32.0 Mild depressive episode	0.000	0.996	0.004
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.000	0.996	0.004
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.004	0.996	0.000
C79 Secondary malignant neoplasm of other sites	0.004	0.996	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.000	0.996	0.004
M21 Other acquired deformities of limbs	0.004	0.996	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.004	0.996	0.000
Q66 Congenital deformities of feet	0.004	0.996	0.000
Q66.2 Metatarsus varus	0.004	0.996	0.000
D44.3 Pituitary gland	0.000	0.996	0.004
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.004	0.996	0.000
M21.6 Other acquired deformities of ankle and foot	0.004	0.996	0.000
H47.1 Papilloedema, unspecified	0.000	0.996	0.004
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.996	0.004
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.996	0.004
D43.4 Spinal cord	0.000	0.996	0.004
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.996	0.004
D43.9 Central nervous system, unspecified	0.000	0.996	0.004
D43.7 Other parts of central nervous system	0.000	0.996	0.004
D43.3 Cranial nerves	0.000	0.996	0.004
C79.8 Secondary malignant neoplasm of other specified sites	0.004	0.996	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.996	0.000
M21.4 Flat foot [pes planus] (acquired)	0.004	0.996	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.004	0.996	0.000
F32.8 Other depressive episodes	0.000	0.996	0.004
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified	0.000	0.996	0.004
Q66.8 Other congenital deformities of feet	0.004	0.996	0.000
D44.7 Aortic body and other paraganglia	0.000	0.996	0.004
D48.7 Other specified sites	0.000	0.996	0.004
Q66.7 Pes cavus	0.004	0.996	0.000
D44.6 Carotid body	0.000	0.996	0.004
K65.9 Peritonitis, unspecified	0.004	0.996	0.000
D44.0 Thyroid gland	0.000	0.996	0.004
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.996	0.004
C91.0 Acute lymphoblastic leukaemia	0.000	0.996	0.004
D48.2 Peripheral nerves and autonomic nervous system	0.000	0.996	0.004
T42.4 Benzodiazepines	0.004	0.996	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.004	0.996	0.000
D48.4 Peritoneum	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.000	0.996	0.004
D68 Other coagulation defects	0.000	0.996	0.004
D44.1 Adrenal gland	0.000	0.996	0.003
T81 Complications of procedures, not elsewhere classified	0.004	0.996	0.000
S50.9 Superficial injury of forearm, unspecified	0.004	0.996	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.003	0.996	0.000
C69.3 Choroid	0.003	0.996	0.000
D68.6 Other Thrombophilia	0.000	0.996	0.003
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.003	0.997	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
D48.3 Retroperitoneum	0.000	0.997	0.003
D44.5 Pineal gland	0.000	0.997	0.003
D44.2 Parathyroid gland	0.000	0.997	0.003
Q66.3 Other congenital varus deformities of feet	0.003	0.997	0.000
D48.6 Breast	0.000	0.997	0.003
J92.9 Pleural plaque without asbestos	0.000	0.997	0.003
M87.9 Osteonecrosis, unspecified	0.003	0.997	0.000
F41 Other anxiety disorders	0.000	0.997	0.003
Q66.5 Congenital pes planus	0.003	0.997	0.000
Q66.4 Talipes calcaneovalgus	0.003	0.997	0.000
Q66.1 Talipes calcaneovarus	0.003	0.997	0.000
D41.0 Kidney	0.000	0.997	0.003
Q66.9 Congenital deformity of feet, unspecified	0.003	0.997	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.997	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.997	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.997	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.997	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.997	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.997	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.997	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.997	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.997	0.000
D41.2 Ureter	0.000	0.997	0.003
D48.0 Bone and articular cartilage	0.000	0.997	0.003
H47.2 Optic atrophy	0.000	0.997	0.003
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
D68.0 Von Willebrand's disease	0.000	0.997	0.003
D41.9 Urinary organ, unspecified	0.000	0.997	0.003
D41.7 Other urinary organs	0.000	0.997	0.003
D41.3 Urethra	0.000	0.997	0.003
D44.4 Craniopharyngeal duct	0.000	0.997	0.003
D68.1 Hereditary factor XI deficiency	0.000	0.997	0.003
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.997	0.003
L03.2 Cellulitis of face	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.997	0.003
H47.6 Disorders of visual cortex	0.000	0.997	0.003
H47.4 Disorders of optic chiasm	0.000	0.997	0.003
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.000	0.997	0.003
F32.3 Severe depressive episode with psychotic symptoms	0.000	0.997	0.003
D44.9 Endocrine gland, unspecified	0.000	0.997	0.003
Q65.8 Other congenital deformities of hip	0.003	0.997	0.000
T42.1 Iminostilbenes	0.003	0.997	0.000
T81.9 Unspecified complication of procedure	0.003	0.997	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.003	0.997	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.003	0.997	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.003	0.997	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.003	0.997	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.003	0.997	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.003	0.997	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.003	0.997	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.997	0.003
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.997	0.000
Z90.0 Acquired absence of part of head and neck	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.997	0.000
C91 Lymphoid leukaemia	0.000	0.997	0.003
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.997	0.003
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.000	0.997	0.003
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.003	0.997	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.003	0.997	0.000
Q66.0 Talipes equinovarus	0.003	0.997	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.997	0.003
F41.8 Other specified anxiety disorders	0.000	0.997	0.003
D44.8 Pluriglandular involvement	0.000	0.997	0.003
L03.8 Cellulitis of other sites	0.003	0.997	0.000
M21.8 Other specified acquired deformities of limbs	0.003	0.997	0.000
D47.4 Osteomyelofibrosis	0.000	0.997	0.003
R49.0 Dysphonia	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.000	0.997	0.003
M21.9 Acquired deformity of limb, unspecified	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.003	0.997	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.003	0.997	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.000	0.997	0.003
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.000	0.997	0.003
M21.7 Unequal limb length (acquired)	0.003	0.997	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.003	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.003	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.003	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.003	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.003	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.003	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.003	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.003	0.997	0.000
Q79.6 Ehlers-Danlos syndrome	0.003	0.997	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.997	0.000
D41.1 Renal pelvis	0.000	0.997	0.002
C91.4 Hairy-cell leukaemia	0.000	0.997	0.003
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.003	0.997	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.997	0.003
M21.33 Wrist or foot drop (acquired) (Forearm)	0.003	0.997	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.003	0.997	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.003	0.997	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.003	0.997	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.003	0.997	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.003	0.997	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.003	0.997	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.997	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.003	0.997	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.997	0.003
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.997	0.003
D68.5 Primary Thrombophilia	0.000	0.997	0.003
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.003
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.003	0.997	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.000	0.997	0.003
F41.3 Other mixed anxiety disorders	0.000	0.997	0.002
G00.9 Bacterial meningitis, unspecified	0.000	0.997	0.003
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.003	0.997	0.000
D42.1 Spinal meninges	0.000	0.997	0.002
D42.0 Cerebral meninges	0.000	0.997	0.002
J38.3 Other diseases of vocal cords	0.000	0.997	0.003
M50.1 Cervical disk disorder with radiculopathy	0.000	0.997	0.003
D45 Polycythaemia vera	0.000	0.997	0.003
D42.9 Meninges, unspecified	0.000	0.997	0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.997	0.002
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.997	0.000
Q70 Syndactyly	0.002	0.997	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.002	0.998	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.002	0.998	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.002	0.998	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.002	0.998	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.002	0.998	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.002	0.998	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.002	0.998	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.000	0.998	0.002
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.998	0.002
C91.7 Other lymphoid leukaemia	0.000	0.998	0.002
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.998	0.002
C91.3 Prolymphocytic leukaemia	0.000	0.998	0.002
C91.2 Subacute lymphocytic leukaemia	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
D38.5 Other respiratory organs	0.000	0.998	0.002
Y60.9 During unspecified surgical and medical care	0.000	0.998	0.002
Y60.7 During administration of enema	0.000	0.998	0.002
Y60.3 During injection or immunisation	0.000	0.998	0.002
Y60.2 During kidney dialysis or other perfusion	0.000	0.998	0.002
Y60.1 During infusion or transfusion	0.000	0.998	0.002
H46 Optic neuritis	0.000	0.998	0.002
W21 Striking against or struck by sports equipment	0.000	0.998	0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
F41.1 Generalised anxiety disorder	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
C90.0 Multiple myeloma	0.000	0.998	0.002
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
D39.7 Other female genital organs	0.000	0.998	0.002
Z96.1 Presence of intraocular lens	0.000	0.998	0.002
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.002	0.998	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.002	0.998	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.002	0.998	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.002	0.998	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.002	0.998	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.002	0.998	0.000
C91.5 Adult T-cell leukaemia	0.000	0.998	0.002
G40.9 Epilepsy, unspecified	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.000	0.998	0.002
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.002	0.998	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.002	0.998	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.002	0.998	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.002	0.998	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.002	0.998	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.002	0.998	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.002	0.998	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.002	0.998	0.000
D39.9 Female genital organ, unspecified	0.000	0.998	0.002
D39.2 Placenta	0.000	0.998	0.002
D40.0 Prostate	0.000	0.998	0.002
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.002	0.998	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.002	0.998	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.002	0.998	0.000
Q79.5 Other congenital malformations of abdominal wall	0.002	0.998	0.000
Q79.4 Prune belly syndrome	0.002	0.998	0.000
Q79.3 Gastroschisis	0.002	0.998	0.000
Q79.2 Exomphalos	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
Q79.0 Congenital diaphragmatic hernia	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.000	0.998	0.002
F84.5 Asperger's syndrome	0.000	0.998	0.002
L03.9 Cellulitis, unspecified	0.002	0.998	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.002	0.998	0.000
M21.78 Unequal limb length (acquired)-Other	0.002	0.998	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.002	0.998	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.002	0.998	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.002	0.998	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.002	0.998	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
D38.6 Respiratory organ, unspecified	0.000	0.998	0.002
D38.4 Thymus	0.000	0.998	0.002
D38.3 Mediastinum	0.000	0.998	0.002
D38.2 Pleura	0.000	0.998	0.002
D40.9 Male genital organ, unspecified	0.000	0.998	0.002
F33 Recurrent depressive disorder	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.998	0.002
Q68.5 Congenital bowing of long bones of leg, unspecified	0.002	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.002	0.998	0.000
Q68.3 Congenital bowing of femur	0.002	0.998	0.000
Q68.2 Congenital deformity of knee	0.002	0.998	0.000
Q68.1 Congenital deformity of hand	0.002	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.002	0.998	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.002	0.998	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.998	0.002
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.002	0.998	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.002	0.998	0.000
R10.0 Acute abdomen	0.002	0.998	0.000
D37.2 Small intestine	0.000	0.998	0.002
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.998	0.002
M21.73 Unequal limb length (acquired) (Forearm)	0.002	0.998	0.000
D09.7 Carcinoma in situ of other specified sites	0.000	0.998	0.002
D09.3 Thyroid and other endocrine glands	0.000	0.998	0.002
D09.2 Eye	0.000	0.998	0.002
Y60.5 During heart catheterisation	0.000	0.998	0.002
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.002	0.998	0.000
D09.9 Carcinoma in situ, unspecified	0.000	0.998	0.002
D39.0 Uterus	0.000	0.998	0.002
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
D09.1 Other and unspecified urinary organs	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
Q70.3 Webbed toes	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
O63 Long labour	0.002	0.998	0.000
D38.0 Larynx	0.000	0.998	0.002
Q70.9 Syndactyly, unspecified	0.002	0.998	0.000
Q70.4 Polysyndactyly	0.002	0.998	0.000
Q70.2 Fused toes	0.002	0.998	0.000
Q70.1 Webbed fingers	0.002	0.998	0.000
Q70.0 Fused fingers	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
Y60.8 During other surgical and medical care	0.000	0.998	0.002
Z36.9 Antenatal screening, unspecified	0.002	0.998	0.000
Q76.5 Cervical rib	0.002	0.998	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.998	0.000
C90.3 Solitary plasmacytoma	0.000	0.998	0.002
D39.1 Ovary	0.000	0.998	0.002
D40.7 Other male genital organs	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.002	0.998	0.000
Q69.9 Polydactyly, unspecified	0.002	0.998	0.000
Q69.2 Accessory toe(s)	0.002	0.998	0.000
Q69.1 Accessory thumb(s)	0.002	0.998	0.000
Q69.0 Accessory finger(s)	0.002	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.002	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations