TreeWAS – Variant ID: rs4282339

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N28.8 Other specified disorders of kidney and ureter	0.000	0.672	0.328
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.685	0.315
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.698	0.302
N28.1 Cyst of kidney, acquired	0.000	0.722	0.278
N28.0 Ischaemia and infarction of kidney	0.000	0.758	0.242
N25-N29 Other disorders of kidney and ureter	0.000	0.859	0.141
N26 Unspecified contracted kidney	0.000	0.892	0.108
N27 Small kidney of unknown cause	0.000	0.893	0.107
N25 Disorders resulting from impaired renal tubular function	0.000	0.901	0.099
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.000	0.907	0.092
C77.1 Intrathoracic lymph nodes	0.000	0.912	0.088
N27.1 Small kidney, bilateral	0.000	0.915	0.084
N27.9 Small kidney, unspecified	0.000	0.923	0.077
N27.0 Small kidney, unilateral	0.000	0.924	0.076
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.929	0.071
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.000	0.929	0.071
N25.1 Nephrogenic diabetes insipidus	0.000	0.929	0.071
N25.0 Renal osteodystrophy	0.000	0.929	0.071
C77.0 Lymph nodes of head, face and neck	0.000	0.929	0.071
N25.8 Other disorders resulting from impaired renal tubular function	0.000	0.931	0.069
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.000	0.933	0.066
N29.0 Late syphilis of kidney	0.000	0.933	0.066
C77.5 Intrapelvic lymph nodes	0.000	0.935	0.065
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.000	0.942	0.058
C77.8 Lymph nodes of multiple regions	0.000	0.942	0.058
C77.2 Intra-abdominal lymph nodes	0.000	0.946	0.054
C77.4 Inguinal and lower limb lymph nodes	0.000	0.957	0.043
C77.9 Lymph node, unspecified	0.000	0.960	0.040
N81.5 Vaginal enterocele	0.000	0.961	0.039
N81.8 Other female genital prolapse	0.000	0.962	0.038
N81 Female genital prolapse	0.000	0.963	0.037
N81.0 Female urethrocele	0.000	0.965	0.035
N81.3 Complete uterovaginal prolapse	0.000	0.969	0.031
N81.6 Rectocele	0.000	0.970	0.030
N81.9 Female genital prolapse, unspecified	0.000	0.971	0.029
Q21.1 Atrial septal defect	0.000	0.974	0.026
N81.1 Cystocele	0.000	0.979	0.021
N81.2 Incomplete uterovaginal prolapse	0.000	0.979	0.021
C34.1 Upper lobe, bronchus or lung	0.000	0.983	0.017
C34 Malignant neoplasm of bronchus and lung	0.000	0.983	0.017
Q21 Congenital malformations of cardiac septa	0.000	0.984	0.016
C34.0 Main bronchus	0.000	0.984	0.016
C34.3 Lower lobe, bronchus or lung	0.000	0.985	0.015
I46.9 Cardiac arrest, unspecified	0.000	0.985	0.015
C34.9 Bronchus or lung, unspecified	0.000	0.986	0.014
Q23.1 Congenital insufficiency of aortic valve	0.000	0.987	0.013
N81.4 Uterovaginal prolapse, unspecified	0.000	0.988	0.012
C34.8 Overlapping lesion of bronchus and lung	0.000	0.988	0.012
Q21.8 Other congenital malformations of cardiac septa	0.000	0.988	0.012
Q21.4 Aortopulmonary septal defect	0.000	0.988	0.012
Q21.2 Atrioventricular septal defect	0.000	0.988	0.012
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.988	0.012
Q23 Congenital malformations of aortic and mitral valves	0.000	0.988	0.012
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.988	0.012
C34.2 Middle lobe, bronchus or lung	0.000	0.989	0.011
Q21.0 Ventricular septal defect	0.000	0.989	0.011
Q21.3 Tetralogy of Fallot	0.000	0.989	0.011
Z63.8 Other specified problems related to primary support group	0.010	0.990	0.000
Z63 Other problems related to primary support group, including family circumstances	0.009	0.991	0.000
S70-S79 Injuries to the hip and thigh	0.009	0.991	0.000
Z63.4 Disappearance and death of family member	0.009	0.991	0.000
S72 Fracture of femur	0.009	0.991	0.000
S70 Superficial injury of hip and thigh	0.009	0.991	0.000
Q25 Congenital malformations of great arteries	0.000	0.991	0.009
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.991	0.009
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.991	0.009
Q23.4 Hypoplastic left heart syndrome	0.000	0.991	0.009
Q23.3 Congenital mitral insufficiency	0.000	0.991	0.009
Q23.2 Congenital mitral stenosis	0.000	0.991	0.009
S79 Other and unspecified injuries of hip and thigh	0.009	0.991	0.000
Q26 Congenital malformations of great veins	0.000	0.991	0.008
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.991	0.008
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.991	0.008
Q24 Other congenital malformations of heart	0.000	0.992	0.008
S72.0 Fracture of neck of femur	0.008	0.992	0.000
S79.8 Other specified injuries of hip and thigh	0.008	0.992	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.008	0.992	0.000
S72.3 Fracture of shaft of femur	0.008	0.992	0.000
Z63.7 Other stressful life events affecting family and household	0.008	0.992	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.992	0.008
S70.8 Other superficial injuries of hip and thigh	0.008	0.992	0.000
S72.00 Fracture of neck of femur (closed)	0.008	0.992	0.000
Z13.6 Special screening examination for cardiovascular disorders	0.000	0.992	0.008
Q27 Other congenital malformations of peripheral vascular system	0.000	0.992	0.008
S71 Open wound of hip and thigh	0.008	0.992	0.000
S72.30 Fracture of shaft of femur (closed)	0.008	0.992	0.000
Z63.0 Problems in relationship with spouse or partner	0.008	0.992	0.000
S72.9 Fracture of femur, part unspecified	0.007	0.992	0.000
S72.4 Fracture of lower end of femur	0.007	0.992	0.000
S70.1 Contusion of thigh	0.007	0.993	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.993	0.007
Q25.1 Coarctation of aorta	0.000	0.993	0.007
Q28 Other congenital malformations of circulatory system	0.000	0.993	0.007
S72.8 Fractures of other parts of femur	0.007	0.993	0.000
C44.2 Skin of ear and external auricular canal	0.007	0.993	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.007	0.993	0.000
Q25.4 Other congenital malformations of aorta	0.000	0.993	0.007
Z63.9 Problem related to primary support group, unspecified	0.007	0.993	0.000
Z63.3 Absence of family member	0.007	0.993	0.000
Z63.2 Inadequate family support	0.007	0.993	0.000
Z63.1 Problems in relationship with parents and in-laws	0.007	0.993	0.000
S78 Traumatic amputation of hip and thigh	0.007	0.993	0.000
S77 Crushing injury of hip and thigh	0.007	0.993	0.000
S75 Injury of blood vessels at hip and thigh level	0.007	0.993	0.000
S74 Injury of nerves at hip and thigh level	0.007	0.993	0.000
S79.9 Unspecified injury of hip and thigh	0.007	0.993	0.000
S72.7 Multiple fractures of femur	0.007	0.993	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.007	0.993	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.993	0.007
Q25.8 Other congenital malformations of great arteries	0.000	0.993	0.007
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.993	0.007
Q25.5 Atresia of pulmonary artery	0.000	0.993	0.007
Q25.3 Stenosis of aorta	0.000	0.993	0.007
Q25.2 Atresia of aorta	0.000	0.993	0.007
Q25.0 Patent ductus arteriosus	0.000	0.993	0.007
S76 Injury of muscle and tendon at hip and thigh level	0.007	0.993	0.000
Q25.6 Stenosis of pulmonary artery	0.000	0.993	0.007
S70.0 Contusion of hip	0.007	0.993	0.000
S71.1 Open wound of thigh	0.007	0.993	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.993	0.006
Z63.5 Disruption of family by separation and divorce	0.006	0.993	0.000
S79.7 Multiple injuries of hip and thigh	0.006	0.993	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.993	0.007
Z63.6 Dependent relative needing care at home	0.006	0.994	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.994	0.006
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.994	0.006
Q20.6 Isomerism of atrial appendages	0.000	0.994	0.006
Q20.5 Discordant atrioventricular connexion	0.000	0.994	0.006
Q20.4 Double inlet ventricle	0.000	0.994	0.006
Q20.3 Discordant ventriculoarterial connexion	0.000	0.994	0.006
Q20.2 Double outlet left ventricle	0.000	0.994	0.006
Q20.1 Double outlet right ventricle	0.000	0.994	0.006
Q20.0 Common arterial trunk	0.000	0.994	0.006
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.994	0.006
Q22.8 Other congenital malformations of tricuspid valve	0.000	0.994	0.006
Q22.6 Hypoplastic right heart syndrome	0.000	0.994	0.006
Q22.5 Ebstein's anomaly	0.000	0.994	0.006
Q22.4 Congenital tricuspid stenosis	0.000	0.994	0.006
Q22.3 Other congenital malformations of pulmonary valve	0.000	0.994	0.006
Q22.2 Congenital pulmonary valve insufficiency	0.000	0.994	0.006
Q22.1 Congenital pulmonary valve stenosis	0.000	0.994	0.006
Q22.0 Pulmonary valve atresia	0.000	0.994	0.006
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.994	0.006
Q26.8 Other congenital malformations of great veins	0.000	0.994	0.006
Q26.6 Portal vein-hepatic artery fistula	0.000	0.994	0.006
Q26.5 Anomalous portal venous connexion	0.000	0.994	0.006
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.994	0.006
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.994	0.006
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.994	0.006
Q26.1 Persistent left superior vena cava	0.000	0.994	0.006
Q26.0 Congenital stenosis of vena cava	0.000	0.994	0.006
S72.90 Fracture of femur, part unspecified (closed)	0.006	0.994	0.000
S72.40 Fracture of lower end of femur (closed)	0.006	0.994	0.000
Q24.6 Congenital heart block	0.000	0.994	0.006
Q24.4 Congenital subaortic stenosis	0.000	0.994	0.006
Q24.3 Pulmonary infundibular stenosis	0.000	0.994	0.006
Q24.2 Cor triatriatum	0.000	0.994	0.006
Q24.1 Levocardia	0.000	0.994	0.006
S72.01 Fracture of neck of femur (open)	0.006	0.994	0.000
S72.31 Fracture of shaft of femur (open)	0.006	0.994	0.000
Q24.0 Dextrocardia	0.000	0.994	0.006
S72.2 Subtrochanteric fracture	0.006	0.994	0.000
Q24.8 Other specified congenital malformations of heart	0.000	0.994	0.006
Q27.4 Congenital phlebectasia	0.000	0.994	0.006
Q27.2 Other congenital malformations of renal artery	0.000	0.994	0.006
Q27.1 Congenital renal artery stenosis	0.000	0.994	0.006
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.994	0.006
S72.80 Fractures of other parts of femur (closed)	0.006	0.994	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.006	0.994	0.000
S71.7 Multiple open wounds of of hip and thigh	0.006	0.994	0.000
S71.0 Open wound of hip	0.006	0.994	0.000
S72.91 Fracture of femur, part unspecified (open)	0.005	0.994	0.000
S72.41 Fracture of lower end of femur (open)	0.005	0.994	0.000
Q24.5 Malformation of coronary vessels	0.000	0.994	0.005
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.995	0.005
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.995	0.005
Q28.3 Other malformations of cerebral vessels	0.000	0.995	0.005
Q28.1 Other malformations of precerebral vessels	0.000	0.995	0.005
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.995	0.005
S72.81 Fractures of other parts of femur (open)	0.005	0.995	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.995	0.005
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.995	0.005
S73.1 Sprain and strain of hip	0.005	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
S73.0 Dislocation of hip	0.005	0.995	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.005	0.995	0.000
S74.8 Injury of other nerves at hip and thigh level	0.005	0.995	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.005	0.995	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.005	0.995	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.005	0.995	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.005	0.995	0.000
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.005	0.995	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.005	0.995	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.005	0.995	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.005	0.995	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.005	0.995	0.000
S75.0 Injury of femoral artery	0.005	0.995	0.000
S77.2 Crushing injury of hip with thigh	0.005	0.995	0.000
S77.1 Crushing injury of thigh	0.005	0.995	0.000
S77.0 Crushing injury of hip	0.005	0.995	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.005	0.995	0.000
S78.1 Traumatic amputation at level between hip and knee	0.005	0.995	0.000
S78.0 Traumatic amputation at hip joint	0.005	0.995	0.000
S72.71 Multiple fractures of femur (open)	0.005	0.995	0.000
S72.70 Multiple fractures of femur (closed)	0.005	0.995	0.000
S76.1 Injury of quadriceps muscle and tendon	0.005	0.995	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.005	0.995	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.005	0.995	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.005	0.995	0.000
S76.0 Injury of muscle and tendon of hip	0.005	0.995	0.000
S72.1 Pertrochanteric fracture	0.005	0.995	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.005	0.995	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.005	0.995	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
S72.21 Subtrochanteric fracture (open)	0.004	0.995	0.000
I46 Cardiac arrest	0.000	0.995	0.005
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.995	0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.005	0.995	0.000
T40.4 Other synthetic narcotics	0.004	0.995	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.996	0.004
H52.2 Astigmatism	0.004	0.996	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.004	0.996	0.000
I87.8 Other specified disorders of veins	0.004	0.996	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.996	0.004
H52.0 Hypermetropia	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.996	0.004
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.996	0.004
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.996	0.004
C31 Malignant neoplasm of accessory sinuses	0.000	0.996	0.004
C33 Malignant neoplasm of trachea	0.000	0.996	0.004
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.004	0.996	0.000
T39.1 4-Aminophenol derivatives	0.004	0.996	0.000
I63.8 Other cerebral infarction	0.000	0.996	0.004
Z29.1 Prophylactic immunotherapy	0.000	0.996	0.004
C69.3 Choroid	0.004	0.996	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.996	0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.004	0.996	0.000
T46.1 Calcium-channel blockers	0.004	0.996	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.996	0.004
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.004	0.996	0.000
S72.11 Pertrochanteric fracture (open)	0.004	0.996	0.000
T66 Unspecified effects of radiation	0.004	0.996	0.000
W02.9 Unspecified place	0.004	0.996	0.000
C37 Malignant neoplasm of thymus	0.000	0.996	0.004
C15.9 Oesophagus, unspecified	0.000	0.996	0.004
H52.3 Anisometropia and aniseikonia	0.004	0.996	0.000
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.004	0.996	0.000
T40.8 Lysergide [LSD]	0.004	0.996	0.000
T40.7 Cannabis (derivatives)	0.004	0.996	0.000
T40.5 Cocaine	0.004	0.996	0.000
T40.3 Methadone	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
T40.0 Opium	0.004	0.996	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.004	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.004	0.996	0.000
F40.2 Specific (isolated) phobias	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
T75 Effects of other external causes	0.004	0.996	0.000
C69 Malignant neoplasm of eye and adnexa	0.004	0.996	0.000
S42.40 Fracture of lower end of humerus (closed)	0.004	0.996	0.000
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
C30.0 Nasal cavity	0.000	0.996	0.004
T68 Hypothermia	0.004	0.996	0.000
S72.20 Subtrochanteric fracture (closed)	0.004	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.004	0.996	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
H52 Disorders of refraction and accommodation	0.004	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
I42 Cardiomyopathy	0.000	0.996	0.004
C69.0 Conjunctiva	0.004	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.996	0.004
T75.4 Effects of electric current	0.004	0.996	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
I46.1 Sudden cardiac death, so described	0.000	0.996	0.003
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.996	0.004
S42 Fracture of shoulder and upper arm	0.004	0.996	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.996	0.004
S42.4 Fracture of lower end of humerus	0.003	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.003	0.996	0.000
S42.3 Fracture of shaft of humerus	0.003	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
T39.4 Antirheumatics, not elsewhere classified	0.003	0.996	0.000
T39.2 Pyrazolone derivatives	0.003	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.003	0.996	0.000
C30.1 Middle ear	0.000	0.997	0.003
C69.2 Retina	0.003	0.997	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
C69.6 Orbit	0.003	0.997	0.000
Z99.8 Dependence on other enabling machines and devices	0.000	0.997	0.003
S43.1 Dislocation of acromioclavicular joint	0.003	0.997	0.000
T50.4 Drugs affecting uric acid metabolism	0.003	0.997	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.003	0.997	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.997	0.003
T45.2 Vitamins, not elsewhere classified	0.003	0.997	0.000
T75.1 Drowning and nonfatal submersion	0.003	0.997	0.000
S42.30 Fracture of shaft of humerus (closed)	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
C69.9 Eye, unspecified	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
C31.9 Accessory sinus, unspecified	0.000	0.997	0.003
C31.8 Overlapping lesion of accessory sinuses	0.000	0.997	0.003
C31.3 Sphenoidal sinus	0.000	0.997	0.003
C31.2 Frontal sinus	0.000	0.997	0.003
C31.1 Ethmoidal sinus	0.000	0.997	0.003
C31.0 Maxillary sinus	0.000	0.997	0.003
C39.9 Ill-defined sites within the respiratory system	0.000	0.997	0.003
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.997	0.003
C39.0 Upper respiratory tract, part unspecified	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.003	0.997	0.000
T45.8 Other primarily systemic and haematological agents	0.003	0.997	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.003	0.997	0.000
T45.6 Fibrinolysis-affecting drugs	0.003	0.997	0.000
T45.4 Iron and its compounds	0.003	0.997	0.000
T45.3 Enzymes, not elsewhere classified	0.003	0.997	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.003	0.997	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.997	0.003
T70.3 Caisson disease [decompression sickness]	0.003	0.997	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.997	0.003
H52.7 Disorder of refraction, unspecified	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.000	0.997	0.003
S42.2 Fracture of upper end of humerus	0.003	0.997	0.000
C38.4 Pleura	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.003	0.997	0.000
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.997	0.003
C38.2 Posterior mediastinum	0.000	0.997	0.003
C38.1 Anterior mediastinum	0.000	0.997	0.003
C38.0 Heart	0.000	0.997	0.003
S42.1 Fracture of scapula	0.003	0.997	0.000
S42.31 Fracture of shaft of humerus (open)	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T93.2 Sequelae of other fractures of lower limb	0.000	0.997	0.003
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.003
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
K29.4 Chronic atrophic gastritis	0.000	0.997	0.003
T42.0 Hydantoin derivatives	0.003	0.997	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.997	0.003
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.003	0.997	0.000
C69.5 Lachrymal gland and duct	0.003	0.997	0.000
C69.4 Ciliary body	0.003	0.997	0.000
C69.1 Cornea	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T75.8 Other specified effects of external causes	0.003	0.997	0.000
T75.3 Motion sickness	0.003	0.997	0.000
T75.2 Effects of vibration	0.003	0.997	0.000
T75.0 Effects of lightning	0.003	0.997	0.000
S43.0 Dislocation of shoulder joint	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
H52.6 Other disorders of refraction	0.003	0.997	0.000
H52.5 Disorders of accommodation	0.003	0.997	0.000
H52.4 Presbyopia	0.003	0.997	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.997	0.003
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.000	0.997	0.003
I42.4 Endocardial fibroelastosis	0.000	0.997	0.003
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.997	0.003
T11.0 Superficial injury of upper limb, level unspecified	0.003	0.997	0.000
T45.5 Anticoagulants	0.003	0.997	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
T39.0 Salicylates	0.003	0.997	0.000
Z99.2 Dependence on renal dialysis	0.000	0.997	0.003
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.000	0.997	0.003
C38.3 Mediastinum, part unspecified	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
T36.0 Penicillins	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.997	0.003
S43.5 Sprain and strain of acromioclavicular joint	0.003	0.997	0.000
T11 Other injuries of upper limb, level unspecified	0.003	0.997	0.000
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
D32.0 Cerebral meninges	0.003	0.997	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.003	0.997	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.003	0.997	0.000
C15.5 Lower third of oesophagus	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.003	0.997	0.000
T70.8 Other effects of air pressure and water pressure	0.003	0.997	0.000
T70.4 Effects of high-pressure fluids	0.003	0.997	0.000
T70.2 Other and unspecified effects of high altitude	0.003	0.997	0.000
T70.1 Sinus barotrauma	0.003	0.997	0.000
T70.0 Otitic barotrauma	0.003	0.997	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.997	0.000
T47.7 Emetics	0.002	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.997	0.000
T47.5 Digestants	0.002	0.997	0.000
T47.4 Other laxatives	0.002	0.997	0.000
T47.3 Saline and osmotic laxatives	0.002	0.997	0.000
T47.2 Stimulant laxatives	0.002	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.997	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.997	0.003
S42.7 Multiple fractures of clavicle, scapula and humerus	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.003	0.997	0.000
S14 Injury of nerves and spinal cord at neck level	0.003	0.997	0.000
C32.8 Overlapping lesion of larynx	0.000	0.997	0.002
C32.3 Laryngeal cartilage	0.000	0.997	0.002
C32.2 Subglottis	0.000	0.997	0.002
J98.4 Other disorders of lung	0.000	0.997	0.003
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.003	0.997	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.003	0.997	0.000
S43.2 Dislocation of sternoclavicular joint	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.003	0.997	0.000
S42.41 Fracture of lower end of humerus (open)	0.002	0.997	0.000
C32.0 Glottis	0.000	0.997	0.003
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.997	0.003
T11.1 Open wound of upper limb, level unspecified	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.997	0.002
C15 Malignant neoplasm of oesophagus	0.000	0.997	0.003
Z29 Need for other prophylactic measures	0.000	0.997	0.003
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.997	0.000
D26.0 Cervix uteri	0.003	0.997	0.000
S42.21 Fracture of upper end of humerus (open)	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations