TreeWAS – Variant ID: rs4282438

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
J45.9 Asthma, unspecified	0.000	0.002	0.998
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.840	0.160	0.000
M20 Acquired deformities of fingers and toes	0.838	0.162	0.000
M20-M25 Other joint disorders	0.838	0.162	0.000
M50-M54 Other dorsopathies	0.828	0.172	0.000
M20.5 Other deformities of toe(s) (acquired)	0.820	0.180	0.000
M20.1 Hallux valgus (acquired)	0.810	0.190	0.000
M15-M19 Arthrosis	0.774	0.226	0.000
M50 Cervical disk disorders	0.771	0.229	0.000
M86-M90 Other osteopathies	0.761	0.239	0.000
M51 Other intervertebral disk disorders	0.761	0.239	0.000
M16 Coxarthrosis [arthrosis of hip]	0.760	0.240	0.000
M16.0 Primary coxarthrosis, bilateral	0.747	0.253	0.000
M24 Other specific joint derangements	0.736	0.264	0.000
M54 Dorsalgia	0.710	0.290	0.000
M16.1 Other primary coxarthrosis	0.708	0.292	0.000
E03 Other hypothyroidism	0.002	0.298	0.700
M20.4 Other hammer toe(s) (acquired)	0.700	0.300	0.000
M21 Other acquired deformities of limbs	0.688	0.312	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.674	0.326	0.000
M51.2 Other specified intervertebral disk displacement	0.671	0.329	0.000
M30 Polyarteritis nodosa and related conditions	0.671	0.329	0.000
S60-S69 Injuries to the wrist and hand	0.670	0.330	0.000
M50.1 Cervical disk disorder with radiculopathy	0.664	0.336	0.000
M89 Other disorders of bone	0.661	0.339	0.000
M50.3 Other cervical disk degeneration	0.658	0.342	0.000
# Top node	0.658	0.342	0.000
Chapter VIII Diseases of the ear and mastoid process	0.651	0.349	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.641	0.359	0.000
H65-H75 Diseases of middle ear and mastoid	0.641	0.359	0.000
M60-M63 Disorders of muscles	0.639	0.361	0.000
M90 Osteopathies in diseases classified elsewhere	0.634	0.366	0.000
M91-M94 Chondropathies	0.633	0.367	0.000
M20.2 Hallux rigidus	0.627	0.373	0.000
S68 Traumatic amputation of wrist and hand	0.626	0.373	0.000
M40-M43 Deforming dorsopathies	0.625	0.375	0.000
M50.2 Other cervical disk displacement	0.623	0.377	0.000
M22 Disorders of patella	0.622	0.378	0.000
M54.1 Radiculopathy	0.621	0.379	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.616	0.384	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.614	0.386	0.000
M54.5 Low back pain	0.612	0.388	0.000
M65-M68 Disorders of synovium and tendon	0.610	0.390	0.000
M80-M85 Disorders of bone density and structure	0.604	0.396	0.000
M00-M03 Infectious arthropathies	0.602	0.398	0.000
M24.1 Other articular cartilage disorders	0.602	0.398	0.000
H72 Perforation of tympanic membrane	0.601	0.399	0.000
Chapter VI Diseases of the nervous system	0.601	0.399	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.601	0.399	0.000
M33 Dermatopolymyositis	0.601	0.399	0.000
M32 Systemic lupus erythematosus	0.601	0.399	0.000
M25 Other joint disorders, not elsewhere classified	0.596	0.404	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.595	0.405	0.000
S67 Crushing injury of wrist and hand	0.594	0.406	0.000
S40-S49 Injuries to the shoulder and upper arm	0.593	0.407	0.000
H66 Suppurative and unspecified otitis media	0.593	0.407	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.592	0.408	0.000
M24.2 Disorder of ligament	0.591	0.409	0.000
M34 Systemic sclerosis	0.590	0.410	0.000
M45-M49 Spondylopathies	0.590	0.410	0.000
M89.9 Disorder of bone, unspecified	0.589	0.411	0.000
S64 Injury of nerves at wrist and hand level	0.586	0.414	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.582	0.418	0.000
G90-G99 Other disorders of the nervous system	0.582	0.418	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.580	0.420	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.574	0.426	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.573	0.427	0.000
M53 Other dorsopathies, not elsewhere classified	0.571	0.429	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.565	0.435	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.565	0.435	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.561	0.439	0.000
M54.12 Radiculopathy (Cervical region)	0.557	0.443	0.000
H66.9 Otitis media, unspecified	0.557	0.443	0.000
M54.4 Lumbago with sciatica	0.555	0.445	0.000
M15 Polyarthrosis	0.555	0.445	0.000
M51.8 Other specified intervertebral disk disorders	0.554	0.446	0.000
M87 Osteonecrosis	0.554	0.446	0.000
M50.9 Cervical disk disorder, unspecified	0.553	0.447	0.000
M50.8 Other cervical disk disorders	0.553	0.447	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.552	0.447	0.000
G95 Other diseases of spinal cord	0.553	0.447	0.000
S61 Open wound of wrist and hand	0.552	0.448	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.551	0.449	0.000
H90-H95 Other disorders of ear	0.551	0.449	0.000
M86 Osteomyelitis	0.551	0.449	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.547	0.453	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.547	0.453	0.000
M21.2 Flexion deformity	0.546	0.454	0.000
M51.3 Other specified intervertebral disk degeneration	0.546	0.454	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.546	0.454	0.000
M51.9 Intervertebral disk disorder, unspecified	0.546	0.454	0.000
M51.4 Schmorl's nodes	0.546	0.454	0.000
M70-M79 Other soft tissue disorders	0.545	0.455	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.545	0.455	0.000
M16.5 Other posttraumatic coxarthrosis	0.545	0.455	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.545	0.455	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.545	0.455	0.000
M21.3 Wrist or foot drop (acquired)	0.544	0.456	0.000
M90.7 Fracture of bone in neoplastic disease	0.543	0.457	0.000
M88 Paget's disease of bone [osteitis deformans]	0.543	0.457	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.539	0.461	0.000
M20.3 Other deformity of hallux (acquired)	0.538	0.462	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.538	0.462	0.000
M50.0 Cervical disk disorder with myelopathy	0.537	0.463	0.000
M54.3 Sciatica	0.534	0.466	0.000
Chapter V Mental and behavioural disorders	0.533	0.467	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.531	0.469	0.000
S60 Superficial injury of wrist and hand	0.528	0.472	0.000
M24.9 Joint derangement, unspecified	0.528	0.472	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.528	0.472	0.000
M24.7 Protrusio acetabuli	0.528	0.472	0.000
M24.6 Ankylosis of joint	0.528	0.472	0.000
M24.5 Contracture of joint	0.528	0.472	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.528	0.472	0.000
M24.0 Loose body in joint	0.528	0.472	0.000
M16.3 Other dysplastic coxarthrosis	0.527	0.473	0.000
M20.0 Deformity of finger(s)	0.527	0.473	0.000
S32 Fracture of lumbar spine and pelvis	0.525	0.475	0.000
H73 Other disorders of tympanic membrane	0.525	0.475	0.000
S70-S79 Injuries to the hip and thigh	0.520	0.479	0.000
M16.7 Other secondary coxarthrosis	0.520	0.480	0.000
M67 Other disorders of synovium and tendon	0.518	0.482	0.000
M54.56 Low back pain (Lumbar region)	0.514	0.486	0.000
Chapter XXII Codes for special purposes	0.512	0.488	0.000
H60-H62 Diseases of external ear	0.512	0.488	0.000
S64.1 Injury of median nerve at wrist and hand level	0.510	0.490	0.000
M21.6 Other acquired deformities of ankle and foot	0.509	0.491	0.000
M54.8 Other dorsalgia	0.509	0.491	0.000
M54.0 Panniculitis affecting regions of neck and back	0.509	0.491	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.509	0.491	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.506	0.494	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.506	0.494	0.000
T51 Toxic effect of alcohol	0.505	0.495	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.505	0.495	0.000
E03.8 Other specified hypothyroidism	0.002	0.496	0.502
E03.5 Myxoedema coma	0.002	0.496	0.502
E03.4 Atrophy of thyroid (acquired)	0.002	0.496	0.502
E03.3 Postinfectious hypothyroidism	0.002	0.496	0.502
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.496	0.502
E03.1 Congenital hypothyroidism without goitre	0.002	0.496	0.502
E03.0 Congenital hypothyroidism with diffuse goitre	0.002	0.496	0.502
D80-D89 Certain disorders involving the immune mechanism	0.503	0.497	0.000
S10-S19 Injuries to the neck	0.497	0.503	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.496	0.504	0.000
Chapter I Certain infectious and parasitic diseases	0.496	0.504	0.000
G90 Disorders of autonomic nervous system	0.496	0.504	0.000
M62 Other disorders of muscle	0.495	0.505	0.000
M21.9 Acquired deformity of limb, unspecified	0.493	0.507	0.000
M21.8 Other specified acquired deformities of limbs	0.493	0.507	0.000
M21.7 Unequal limb length (acquired)	0.493	0.507	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.493	0.507	0.000
M21.4 Flat foot [pes planus] (acquired)	0.493	0.507	0.000
S69 Other and unspecified injuries of wrist and hand	0.493	0.507	0.000
G95.9 Disease of spinal cord, unspecified	0.493	0.507	0.000
M21.0 Valgus deformity, not elsewhere classified	0.492	0.508	0.000
H74 Other disorders of middle ear and mastoid	0.492	0.508	0.000
M31 Other necrotising vasculopathies	0.491	0.508	0.000
E00-E07 Disorders of thyroid gland	0.005	0.510	0.485
M54.6 Pain in thoracic spine	0.488	0.511	0.000
M24.24 Disorder of ligament (Hand)	0.487	0.513	0.000
M93 Other osteochondropathies	0.486	0.513	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.486	0.514	0.000
S20-S29 Injuries to the thorax	0.485	0.515	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.485	0.515	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.485	0.515	0.000
T66-T78 Other and unspecified effects of external causes	0.484	0.515	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.485	0.515	0.000
T33-T35 Frostbite	0.484	0.516	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.484	0.516	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.484	0.516	0.000
T00-T07 Injuries involving multiple body regions	0.484	0.516	0.000
T91 Sequelae of injuries of neck and trunk	0.483	0.517	0.000
M85 Other disorders of bone density and structure	0.482	0.518	0.000
G95.8 Other specified diseases of spinal cord	0.481	0.519	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.481	0.519	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.481	0.519	0.000
M30.2 Juvenile polyarteritis	0.481	0.519	0.000
M30.0 Polyarteritis nodosa	0.481	0.519	0.000
S65 Injury of blood vessels at wrist and hand level	0.481	0.519	0.000
S64.3 Injury of digital nerve of thumb	0.480	0.519	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.480	0.520	0.000
H72.0 Central perforation of tympanic membrane	0.480	0.520	0.000
S40 Superficial injury of shoulder and upper arm	0.480	0.520	0.000
T79-T79 Certain early complications of trauma	0.479	0.520	0.000
M22.2 Patellofemoral disorders	0.479	0.520	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.479	0.521	0.000
M22.3 Other derangements of patella	0.479	0.521	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.475	0.525	0.000
M89.8 Other specified disorders of bone	0.474	0.526	0.000
M89.6 Osteopathy after poliomyelitis	0.474	0.526	0.000
M89.5 Osteolysis	0.474	0.526	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.474	0.526	0.000
M89.3 Hypertrophy of bone	0.474	0.526	0.000
M89.2 Other disorders of bone development and growth	0.474	0.526	0.000
M89.1 Epiphyseal arrest	0.474	0.526	0.000
M89.0 Algoneurodystrophy	0.474	0.526	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.473	0.527	0.000
M21.1 Varus deformity, not elsewhere classified	0.472	0.527	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.472	0.528	0.000
H91 Other hearing loss	0.471	0.529	0.000
Chapter XX External causes of morbidity and mortality	0.471	0.529	0.000
S90-S99 Injuries to the ankle and foot	0.470	0.529	0.000
Q60-Q64 Congenital malformations of the urinary system	0.470	0.530	0.000
H65 Nonsuppurative otitis media	0.467	0.533	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.467	0.533	0.000
M43 Other deforming dorsopathies	0.465	0.535	0.000
T14 Injury of unspecified body region	0.465	0.535	0.000
M54.57 Low back pain (Lumbosacral region)	0.465	0.535	0.000
T86 Failure and rejection of transplanted organs and tissues	0.465	0.535	0.000
M54.50 Low back pain (Multiple sites in spine)	0.463	0.537	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.463	0.537	0.000
F25 Schizoaffective disorders	0.462	0.537	0.000
M22.4 Chondromalacia patellae	0.462	0.538	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.461	0.539	0.000
M54.59 Low back pain (Site unspecified)	0.461	0.539	0.000
M54.36 Sciatica (Lumbar region)	0.461	0.539	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.460	0.540	0.000
H70 Mastoiditis and related conditions	0.460	0.540	0.000
H69 Other disorders of Eustachian tube	0.460	0.540	0.000
H68 Eustachian salpingitis and obstruction	0.460	0.540	0.000
H67 Otitis media in diseases classified elsewhere	0.460	0.540	0.000
S61.8 Open wound of other parts of wrist and hand	0.459	0.541	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.458	0.542	0.000
M61 Calcification and ossification of muscle	0.458	0.542	0.000
M60 Myositis	0.458	0.542	0.000
M19 Other arthrosis	0.458	0.542	0.000
M84 Disorders of continuity of bone	0.457	0.543	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.456	0.544	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.456	0.544	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.455	0.545	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.455	0.545	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.455	0.545	0.000
M90.6 Osteitis deformans in neoplastic disease	0.455	0.545	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.455	0.545	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.455	0.545	0.000
M90.3 Osteonecrosis in caisson disease	0.455	0.545	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.455	0.545	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.455	0.545	0.000
M90.0 Tuberculosis of bone	0.455	0.545	0.000
M92 Other juvenile osteochondrosis	0.454	0.546	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.454	0.546	0.000
S32.0 Fracture of lumbar vertebra	0.454	0.546	0.000
D86 Sarcoidosis	0.454	0.546	0.000
M41 Scoliosis	0.454	0.546	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.452	0.548	0.000
M94 Other disorders of cartilage	0.452	0.548	0.000
F20 Schizophrenia	0.451	0.549	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.449	0.551	0.000
S68.8 Traumatic amputation of other parts of wrist and hand	0.449	0.551	0.000
S68.4 Traumatic amputation of hand at wrist level	0.449	0.551	0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.449	0.551	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.449	0.551	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.449	0.551	0.000
M42 Spinal osteochondrosis	0.448	0.552	0.000
M40 Kyphosis and lordosis	0.448	0.552	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.448	0.552	0.000
M18 Arthrosis of first carpometacarpal joint	0.447	0.552	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.447	0.553	0.000
D68 Other coagulation defects	0.446	0.554	0.000
M25.8 Other specified joint disorders	0.446	0.554	0.000
M22.1 Recurrent subluxation of patella	0.446	0.554	0.000
M22.9 Disorder of patella, unspecified	0.446	0.554	0.000
M22.0 Recurrent dislocation of patella	0.446	0.554	0.000
D55-D59 Haemolytic anaemias	0.445	0.554	0.000
M54.19 Radiculopathy (Site unspecified)	0.445	0.555	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.445	0.555	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.445	0.555	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.445	0.555	0.000
M54.14 Radiculopathy (Thoracic region)	0.445	0.555	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.445	0.555	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.445	0.555	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.445	0.555	0.000
M54.16 Radiculopathy (Lumbar region)	0.444	0.555	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.444	0.555	0.000
S42 Fracture of shoulder and upper arm	0.444	0.556	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.444	0.556	0.000
M21.27 Flexion deformity (Ankle and foot)	0.444	0.556	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.443	0.556	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.443	0.557	0.000
T51.9 Alcohol, unspecified	0.443	0.557	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.443	0.557	0.000
M46 Other inflammatory spondylopathies	0.442	0.558	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.441	0.559	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.441	0.559	0.000
H73.8 Other specified disorders of tympanic membrane	0.441	0.559	0.000
T59 Toxic effect of other gases, fumes and vapours	0.440	0.560	0.000
M99 Biomechanical lesions, not elsewhere classified	0.440	0.560	0.000
S50-S59 Injuries to the elbow and forearm	0.439	0.560	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.439	0.561	0.000
M54.55 Low back pain (Thoracolumbar region)	0.439	0.561	0.000
M54.54 Low back pain-Thoracic	0.439	0.561	0.000
M54.53 Low back pain-Cervicothoracic	0.439	0.561	0.000
M54.52 Low back pain-Cervical	0.439	0.561	0.000
M54.51 Low back pain-Occipit-atl-axl	0.439	0.561	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.439	0.561	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.437	0.562	0.000
M66 Spontaneous rupture of synovium and tendon	0.437	0.562	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.436	0.564	0.000
H92 Otalgia and effusion of ear	0.435	0.564	0.000
T98 Sequelae of other and unspecified effects of external causes	0.435	0.565	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.435	0.565	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.434	0.566	0.000
M83 Adult osteomalacia	0.433	0.567	0.000
M82 Osteoporosis in diseases classified elsewhere	0.433	0.567	0.000
M25.4 Effusion of joint	0.433	0.567	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.432	0.567	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.432	0.567	0.000
M17 Gonarthrosis [arthrosis of knee]	0.432	0.568	0.000
H72.8 Other perforations of tympanic membrane	0.432	0.568	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.432	0.568	0.000
M02 Reactive arthropathies	0.432	0.568	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.432	0.568	0.000
M00 Pyogenic arthritis	0.432	0.568	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.431	0.568	0.000
M24.18 Other articular cartilage disorders (Other)	0.431	0.568	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.431	0.568	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.431	0.568	0.000
M24.14 Other articular cartilage disorders (Hand)	0.431	0.568	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.431	0.568	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.431	0.568	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.431	0.568	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.431	0.568	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.432	0.568	0.000
H72.2 Other marginal perforations of tympanic membrane	0.431	0.569	0.000
H72.1 Attic perforation of tympanic membrane	0.431	0.569	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.431	0.569	0.000
M32.8 Other forms of systemic lupus erythematosus	0.431	0.569	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.431	0.569	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.431	0.569	0.000
M33.9 Dermatopolymyositis, unspecified	0.431	0.569	0.000
M33.2 Polymyositis	0.431	0.569	0.000
M33.1 Other dermatomyositis	0.431	0.569	0.000
M33.0 Juvenile dermatomyositis	0.431	0.569	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.431	0.569	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.431	0.569	0.000
M36.3 Arthropathy in other blood disorders	0.431	0.569	0.000
M36.2 Haemophilic arthropathy	0.431	0.569	0.000
M36.1 Arthropathy in neoplastic disease	0.431	0.569	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.431	0.569	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.430	0.570	0.000
G95.2 Cord compression, unspecified	0.430	0.570	0.000
H66.3 Other chronic suppurative otitis media	0.430	0.570	0.000
F25.9 Schizoaffective disorder, unspecified	0.430	0.570	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.428	0.572	0.000
M25.9 Joint disorder, unspecified	0.427	0.573	0.000
M25.3 Other instability of joint	0.427	0.573	0.000
M25.2 Flail joint	0.427	0.573	0.000
M25.1 Fistula of joint	0.427	0.573	0.000
M25.0 Haemarthrosis	0.427	0.573	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.427	0.573	0.000
S70 Superficial injury of hip and thigh	0.427	0.573	0.000
S32.4 Fracture of acetabulum	0.427	0.573	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.426	0.574	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.425	0.575	0.000
S48 Traumatic amputation of shoulder and upper arm	0.425	0.575	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.425	0.575	0.000
S44 Injury of nerves at shoulder and upper arm level	0.425	0.575	0.000
S41 Open wound of shoulder and upper arm	0.425	0.575	0.000
S47 Crushing injury of shoulder and upper arm	0.425	0.575	0.000
H66.4 Suppurative otitis media, unspecified	0.425	0.575	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.425	0.575	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.425	0.575	0.000
H66.0 Acute suppurative otitis media	0.425	0.575	0.000
Q28 Other congenital malformations of circulatory system	0.425	0.575	0.000
T87 Complications peculiar to reattachment and amputation	0.424	0.575	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.424	0.575	0.000
Q00-Q07 Congenital malformations of the nervous system	0.424	0.576	0.000
M24.29 Disorder of ligament (Site unspecified)	0.424	0.576	0.000
M24.28 Disorder of ligament (Other)	0.424	0.576	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.424	0.576	0.000
M24.26 Disorder of ligament (Lower leg)	0.424	0.576	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.424	0.576	0.000
M24.23 Disorder of ligament (Forearm)	0.424	0.576	0.000
M24.22 Disorder of ligament (Upper arm)	0.424	0.576	0.000
M24.21 Disorder of ligament (Shoulder region)	0.424	0.576	0.000
M24.20 Disorder of ligament (Multiple sites)	0.424	0.576	0.000
M34.8 Other forms of systemic sclerosis	0.423	0.577	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.423	0.577	0.000
M34.1 CR(E)ST syndrome	0.423	0.577	0.000
M34.0 Progressive systemic sclerosis	0.423	0.577	0.000
M49 Spondylopathies in diseases classified elsewhere	0.423	0.577	0.000
M70 Soft tissue disorders related to use, overuse and pressure	0.423	0.577	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.422	0.577	0.000
M89.98 Disorder of bone, unspecified (Other)	0.422	0.577	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.422	0.577	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.422	0.577	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.422	0.577	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.422	0.577	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.422	0.577	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.422	0.577	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.422	0.577	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.422	0.578	0.000
T90 Sequelae of injuries of head	0.422	0.578	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.421	0.579	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.421	0.579	0.000
G70-G73 Diseases of myoneural junction and muscle	0.421	0.579	0.000
G30-G32 Other degenerative diseases of the nervous system	0.421	0.579	0.000
S64.9 Injury of unspecified nerve at wrist and hand level	0.420	0.579	0.000
S64.8 Injury of other nerves at wrist and hand level	0.420	0.579	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.420	0.579	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.420	0.579	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.420	0.579	0.000
S62 Fracture at wrist and hand level	0.419	0.581	0.000
M54.37 Sciatica (Lumbosacral region)	0.419	0.581	0.000
M48 Other spondylopathies	0.419	0.581	0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.419	0.581	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.418	0.582	0.000
T65 Toxic effect of other and unspecified substances	0.417	0.582	0.000
T63 Toxic effect of contact with venomous animals	0.417	0.582	0.000
T62 Toxic effect of other noxious substances eaten as food	0.417	0.582	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.417	0.582	0.000
T60 Toxic effect of pesticides	0.417	0.582	0.000
T57 Toxic effect of other inorganic substances	0.417	0.582	0.000
T56 Toxic effect of metals	0.417	0.582	0.000
T54 Toxic effect of corrosive substances	0.417	0.582	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.417	0.582	0.000
T52 Toxic effect of organic solvents	0.417	0.582	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.417	0.582	0.000
T58 Toxic effect of carbon monoxide	0.417	0.582	0.000
T55 Toxic effect of soaps and detergents	0.417	0.582	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.417	0.583	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.417	0.583	0.000
G92 Toxic encephalopathy	0.417	0.583	0.000
S60.8 Other superficial injuries of wrist and hand	0.417	0.583	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.416	0.584	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.416	0.584	0.000
Q80-Q89 Other congenital malformations	0.416	0.584	0.000
Q50-Q56 Congenital malformations of genital organs	0.416	0.584	0.000
Q35-Q37 Cleft lip and cleft palate	0.416	0.584	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.416	0.584	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.416	0.584	0.000
E07 Other disorders of thyroid	0.003	0.585	0.412
T84.2 Mechanical complication of internal fixation device of other bones	0.415	0.585	0.000
G93 Other disorders of brain	0.415	0.585	0.000
M67.8 Other specified disorders of synovium and tendon	0.415	0.585	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.415	0.585	0.000
M80 Osteoporosis with pathological fracture	0.414	0.586	0.000
H91.9 Hearing loss, unspecified	0.414	0.586	0.000
M34.9 Systemic sclerosis, unspecified	0.413	0.587	0.000
H60 Otitis externa	0.412	0.588	0.000
G96 Other disorders of central nervous system	0.412	0.588	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.411	0.588	0.000
S37 Injury of urinary and pelvic organs	0.411	0.588	0.000
S36 Injury of intra-abdominal organs	0.411	0.588	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.411	0.588	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.411	0.588	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.411	0.588	0.000
S31 Open wound of abdomen, lower back and pelvis	0.411	0.588	0.000
M67.1 Other contracture of tendon (sheath)	0.411	0.589	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.411	0.589	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.411	0.589	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.411	0.589	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.411	0.589	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.411	0.589	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.411	0.589	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.411	0.589	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.411	0.589	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.411	0.589	0.000
M53.9 Dorsopathy, unspecified	0.410	0.590	0.000
M53.8 Other specified dorsopathies	0.410	0.590	0.000
M53.2 Spinal instabilities	0.410	0.590	0.000
M53.1 Cervicobrachial syndrome	0.410	0.590	0.000
M53.0 Cervicocranial syndrome	0.410	0.590	0.000
M79.6 Pain in limb	0.410	0.590	0.000
M05-M14 Inflammatory polyarthropathies	0.409	0.591	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.409	0.591	0.000
M45 Ankylosing spondylitis	0.409	0.591	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.408	0.591	0.000
M25.5 Pain in joint	0.408	0.592	0.000
M47 Spondylosis	0.407	0.593	0.000
T95 Sequelae of burns, corrosions and frostbite	0.405	0.594	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.405	0.594	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.405	0.594	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.405	0.594	0.000
M87.9 Osteonecrosis, unspecified	0.405	0.595	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.404	0.596	0.000
T92 Sequelae of injuries of upper limb	0.403	0.596	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.403	0.597	0.000
M79.0 Rheumatism, unspecified	0.403	0.597	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.403	0.597	0.000
T14.0 Superficial injury of unspecified body region	0.403	0.597	0.000
F99-F99 Unspecified mental disorder	0.401	0.599	0.000
M86.9 Osteomyelitis, unspecified	0.400	0.600	0.000
E04 Other non-toxic goitre	0.002	0.600	0.398
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.399	0.601	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.399	0.601	0.000
M54.9 Dorsalgia, unspecified	0.399	0.601	0.000
Q61 Cystic kidney disease	0.398	0.601	0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.398	0.602	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.398	0.602	0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.398	0.602	0.000
M54.44 Lumbago with sciatica-Thoracic	0.398	0.602	0.000
M54.43 Lumbago with sciatica-Cervicothoracic	0.398	0.602	0.000
M54.42 Lumbago with sciatica-Cervical	0.398	0.602	0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.398	0.602	0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.398	0.602	0.000
M15.9 Polyarthrosis, unspecified	0.398	0.602	0.000
M15.0 Primary generalised (osteo)arthrosis	0.398	0.602	0.000
M15.8 Other polyarthrosis	0.398	0.602	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations