TreeWAS – Variant ID: rs4293393

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N20.0 Calculus of kidney	1.000	0.000	0.000
I10 Essential (primary) hypertension	0.000	0.000	1.000
N20 Calculus of kidney and ureter	1.000	0.000	0.000
N20.1 Calculus of ureter	1.000	0.000	0.000
N20.2 Calculus of kidney with calculus of ureter	0.998	0.002	0.000
I10-I15 Hypertensive diseases	0.000	0.016	0.984
I12 Hypertensive renal disease	0.000	0.020	0.980
I12.0 Hypertensive renal disease with renal failure	0.000	0.032	0.968
I12.9 Hypertensive renal disease without renal failure	0.000	0.081	0.919
N20.9 Urinary calculus, unspecified	0.853	0.147	0.000
N18 Chronic renal failure	0.000	0.158	0.842
N18.9 Chronic renal failure, unspecified	0.000	0.161	0.839
N18.3 Chronic kidney disease, stage 3	0.000	0.161	0.839
N17-N19 Renal failure	0.000	0.191	0.808
N17 Acute renal failure	0.000	0.207	0.793
N17.9 Acute renal failure, unspecified	0.000	0.212	0.788
I15 Secondary hypertension	0.000	0.216	0.784
N20-N23 Urolithiasis	0.744	0.256	0.000
N21 Calculus of lower urinary tract	0.729	0.271	0.000
N19 Unspecified renal failure	0.000	0.294	0.706
I13 Hypertensive heart and renal disease	0.000	0.294	0.705
N18.5 Chronic kidney disease, stage 5	0.000	0.295	0.705
N21.0 Calculus in bladder	0.703	0.297	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.333	0.667
I11 Hypertensive heart disease	0.000	0.346	0.654
N21.1 Calculus in urethra	0.650	0.350	0.000
N18.8 Other chronic renal failure	0.000	0.383	0.617
N18.0 End-stage renal disease	0.000	0.425	0.575
N17.2 Acute renal failure with medullary necrosis	0.000	0.431	0.569
N17.1 Acute renal failure with acute cortical necrosis	0.000	0.431	0.569
N18.1 Chronic kidney disease, stage 1	0.000	0.432	0.568
I15.9 Seconday hypertension, unspecified	0.000	0.438	0.562
I15.8 Other secondary hypertension	0.000	0.438	0.562
I15.2 Hypertension secondary to endocrine disorders	0.000	0.438	0.562
N17.8 Other acute renal failure	0.000	0.450	0.549
N22 Calculus of urinary tract in diseases classified elsewhere	0.533	0.466	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.523	0.477	0.000
I15.0 Renovascular hypertension	0.000	0.489	0.511
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.494	0.506
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.494	0.506
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.494	0.506
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.494	0.506
N21.8 Other lower urinary tract calculus	0.497	0.503	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.518	0.482
N18.4 Chronic kidney disease, stage 4	0.000	0.528	0.472
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.549	0.451
N17.0 Acute renal failure with tubular necrosis	0.000	0.558	0.441
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.561	0.439
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.382	0.617	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.382	0.617	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.227	0.773	0.000
N13 Obstructive and reflux uropathy	0.141	0.859	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.135	0.865	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.127	0.873	0.000
N13.6 Pyonephrosis	0.113	0.886	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.107	0.893	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.098	0.902	0.000
N13.4 Hydroureter	0.080	0.920	0.000
N10-N16 Renal tubulo-interstitial diseases	0.068	0.931	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.060	0.939	0.000
N10 Acute tubulo-interstitial nephritis	0.057	0.943	0.000
N11 Chronic tubulo-interstitial nephritis	0.053	0.947	0.000
N15 Other renal tubulo-interstitial diseases	0.052	0.948	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.049	0.950	0.000
N13.3 Other and unspecified hydronephrosis	0.045	0.955	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.045	0.955	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.041	0.959	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.040	0.960	0.000
N11.1 Chronic obstructive pyelonephritis	0.039	0.961	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.038	0.962	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.038	0.962	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.037	0.962	0.000
N15.0 Balkan nephropathy	0.037	0.962	0.000
N15.1 Renal and perinephric abscess	0.037	0.963	0.000
Chapter XIV Diseases of the genitourinary system	0.034	0.964	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.035	0.964	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.035	0.964	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.035	0.964	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.035	0.964	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.035	0.964	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.035	0.964	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.035	0.964	0.000
N13.8 Other obstructive and reflux uropathy	0.034	0.965	0.001
N14.4 Toxic nephropathy, not elsewhere classified	0.032	0.968	0.000
N14.3 Nephropathy induced by heavy metals	0.032	0.968	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.032	0.968	0.000
N14.0 Analgesic nephropathy	0.032	0.968	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.027	0.972	0.000
N99-N99 Other disorders of the genitourinary system	0.027	0.972	0.001
F10.3 Withdrawal state	0.000	0.973	0.027
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.026	0.974	0.000
M86.9 Osteomyelitis, unspecified	0.026	0.974	0.000
M86 Osteomyelitis	0.023	0.977	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.000	0.978	0.022
M86.94 Osteomyelitis, unspecified (Hand)	0.022	0.978	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.022	0.978	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.021	0.978	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.021	0.979	0.000
F10.1 Harmful use	0.000	0.979	0.021
M86.6 Other chronic osteomyelitis	0.021	0.979	0.000
M86.8 Other osteomyelitis	0.020	0.980	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.019	0.981	0.000
M86.1 Other acute osteomyelitis	0.019	0.981	0.000
F10.9 Unspecified mental and behavioural disorder	0.000	0.981	0.019
M86.93 Osteomyelitis, unspecified (Forearm)	0.019	0.981	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.019	0.981	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.019	0.981	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.019	0.981	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.018	0.982	0.000
N23 Unspecified renal colic	0.017	0.982	0.001
N99.5 Malfunction of external stoma of urinary tract	0.018	0.982	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.018	0.982	0.000
F10.5 Psychotic disorder	0.000	0.982	0.018
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.017	0.983	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.017	0.983	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.017	0.983	0.000
M86.3 Chronic multifocal osteomyelitis	0.017	0.983	0.000
M86.2 Subacute osteomyelitis	0.017	0.983	0.000
M86.0 Acute haematogenous osteomyelitis	0.017	0.983	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.017	0.983	0.000
F10.8 Other mental and behavioural disorders	0.000	0.984	0.016
F10.7 Residual and late-onset psychotic disorder	0.000	0.984	0.016
M86.96 Osteomyelitis, unspecified (Lower leg)	0.016	0.984	0.000
F10.6 Amnesic syndrome	0.000	0.984	0.016
M86.17 Other acute osteomyelitis (Ankle and foot)	0.016	0.984	0.000
M86.86 Other osteomyelitis (Lower leg)	0.016	0.984	0.000
N99.1 Postprocedural urethral stricture	0.016	0.984	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.015	0.984	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.015	0.984	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.000	0.985	0.015
M86.66 Other chronic osteomyelitis (Lower leg)	0.015	0.985	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.015	0.985	0.000
M86.68 Other chronic osteomyelitis (Other)	0.015	0.985	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.015	0.985	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.015	0.985	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.015	0.985	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.015	0.985	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.015	0.985	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.015	0.985	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.014	0.985	0.000
M86.88 Other osteomyelitis (Other)	0.014	0.985	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.014	0.985	0.000
M86.84 Other osteomyelitis (Hand)	0.014	0.985	0.000
M86.83 Other osteomyelitis (Forearm)	0.014	0.985	0.000
M86.82 Other osteomyelitis (Upper arm)	0.014	0.985	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.014	0.985	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.014	0.985	0.000
F10.4 Withdrawal state with delirium	0.000	0.985	0.014
N99.3 Prolapse of vaginal vault after hysterectomy	0.014	0.986	0.000
N99.0 Postprocedural renal failure	0.014	0.986	0.000
F10.2 Dependence syndrome	0.000	0.986	0.014
M86.19 Other acute osteomyelitis (Site unspecified)	0.014	0.986	0.000
M86.18 Other acute osteomyelitis (Other)	0.014	0.986	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.014	0.986	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.014	0.986	0.000
M86.14 Other acute osteomyelitis (Hand)	0.014	0.986	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.014	0.986	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.014	0.986	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.014	0.986	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.014	0.986	0.000
N25-N29 Other disorders of kidney and ureter	0.012	0.986	0.002
N99.2 Postprocedural adhesions of vagina	0.013	0.987	0.000
F17.2 Dependence syndrome	0.000	0.987	0.013
F12 Mental and behavioural disorders due to use of cannabinoids	0.000	0.987	0.013
F11 Mental and behavioural disorders due to use of opioids	0.000	0.987	0.013
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.012	0.988	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.012	0.988	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.012	0.988	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.012	0.988	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.012	0.988	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.012	0.988	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.012	0.988	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.012	0.988	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.012	0.988	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.012	0.988	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.012	0.988	0.000
M86.28 Subacute osteomyelitis (Other)	0.012	0.988	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.012	0.988	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.012	0.988	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.012	0.988	0.000
M86.24 Subacute osteomyelitis (Hand)	0.012	0.988	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.012	0.988	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.012	0.988	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.012	0.988	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.012	0.988	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.012	0.988	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.012	0.988	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.012	0.988	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.012	0.988	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.012	0.988	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.012	0.988	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.012	0.988	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.012	0.988	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.012	0.988	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.012	0.988	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.012	0.988	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.012	0.988	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.012	0.988	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.012	0.988	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.012	0.988	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.012	0.988	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.012	0.988	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.012	0.988	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.012	0.988	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.012	0.988	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.012	0.988	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.012	0.988	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.012	0.988	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.012	0.988	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.012	0.988	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.012	0.988	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.012	0.988	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.012	0.988	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.012	0.988	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.012	0.988	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.000	0.988	0.012
F11.2 Dependence syndrome	0.000	0.988	0.012
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.000	0.989	0.011
F18 Mental and behavioural disorders due to use of volatile solvents	0.000	0.989	0.011
F16 Mental and behavioural disorders due to use of hallucinogens	0.000	0.989	0.011
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.000	0.989	0.011
F14 Mental and behavioural disorders due to use of cocaine	0.000	0.989	0.011
F12.1 Harmful use	0.000	0.989	0.011
N00-N08 Glomerular diseases	0.009	0.989	0.002
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.000	0.989	0.011
N27 Small kidney of unknown cause	0.009	0.989	0.001
N25 Disorders resulting from impaired renal tubular function	0.009	0.990	0.001
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.008	0.990	0.001
F12.2 Dependence syndrome	0.000	0.990	0.010
F11.9 Unspecified mental and behavioural disorder	0.000	0.990	0.009
F11.8 Other mental and behavioural disorders	0.000	0.990	0.009
F11.7 Residual and late-onset psychotic disorder	0.000	0.990	0.009
F11.6 Amnesic syndrome	0.000	0.990	0.009
F11.5 Psychotic disorder	0.000	0.990	0.009
F11.4 Withdrawal state with delirium	0.000	0.990	0.009
F11.1 Harmful use	0.000	0.990	0.009
F11.0 Acute intoxication	0.000	0.990	0.009
F12.9 Unspecified mental and behavioural disorder	0.000	0.990	0.009
F12.8 Other mental and behavioural disorders	0.000	0.990	0.009
F12.7 Residual and late-onset psychotic disorder	0.000	0.990	0.009
F12.6 Amnesic syndrome	0.000	0.990	0.009
F12.5 Psychotic disorder	0.000	0.990	0.009
F12.4 Withdrawal state with delirium	0.000	0.990	0.009
F12.3 Withdrawal state	0.000	0.990	0.009
F12.0 Acute intoxication	0.000	0.990	0.009
F17.8 Other mental and behavioural disorders	0.000	0.991	0.009
F17.7 Residual and late-onset psychotic disorder	0.000	0.991	0.009
F17.6 Amnesic syndrome	0.000	0.991	0.009
F17.5 Psychotic disorder	0.000	0.991	0.009
F17.4 Withdrawal state with delirium	0.000	0.991	0.009
F17.3 Withdrawal state	0.000	0.991	0.009
F11.3 Withdrawal state	0.000	0.991	0.009
M86-M90 Other osteopathies	0.009	0.991	0.000
N27.0 Small kidney, unilateral	0.008	0.991	0.001
F10.0 Acute intoxication	0.000	0.991	0.009
F19.1 Harmful use	0.000	0.991	0.008
F19.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
F19.8 Other mental and behavioural disorders	0.000	0.992	0.008
F19.7 Residual and late-onset psychotic disorder	0.000	0.992	0.008
F19.6 Amnesic syndrome	0.000	0.992	0.008
F19.5 Psychotic disorder	0.000	0.992	0.008
F19.4 Withdrawal state with delirium	0.000	0.992	0.008
F19.3 Withdrawal state	0.000	0.992	0.008
F19.2 Dependence syndrome	0.000	0.992	0.008
F19.0 Acute intoxication	0.000	0.992	0.008
F14.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
F14.8 Other mental and behavioural disorders	0.000	0.992	0.008
F14.7 Residual and late-onset psychotic disorder	0.000	0.992	0.008
F14.6 Amnesic syndrome	0.000	0.992	0.008
F14.5 Psychotic disorder	0.000	0.992	0.008
F14.4 Withdrawal state with delirium	0.000	0.992	0.008
F14.3 Withdrawal state	0.000	0.992	0.008
F14.2 Dependence syndrome	0.000	0.992	0.008
F14.1 Harmful use	0.000	0.992	0.008
F14.0 Acute intoxication	0.000	0.992	0.008
F15.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
F15.8 Other mental and behavioural disorders	0.000	0.992	0.008
F15.7 Residual and late-onset psychotic disorder	0.000	0.992	0.008
F15.6 Amnesic syndrome	0.000	0.992	0.008
F15.5 Psychotic disorder	0.000	0.992	0.008
F15.4 Withdrawal state with delirium	0.000	0.992	0.008
F15.3 Withdrawal state	0.000	0.992	0.008
F15.2 Dependence syndrome	0.000	0.992	0.008
F15.1 Harmful use	0.000	0.992	0.008
F15.0 Acute intoxication	0.000	0.992	0.008
F16.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
F16.8 Other mental and behavioural disorders	0.000	0.992	0.008
F16.7 Residual and late-onset psychotic disorder	0.000	0.992	0.008
F16.6 Amnesic syndrome	0.000	0.992	0.008
F16.5 Psychotic disorder	0.000	0.992	0.008
F16.4 Withdrawal state with delirium	0.000	0.992	0.008
F16.3 Withdrawal state	0.000	0.992	0.008
F16.2 Dependence syndrome	0.000	0.992	0.008
F16.1 Harmful use	0.000	0.992	0.008
F16.0 Acute intoxication	0.000	0.992	0.008
F18.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
F18.8 Other mental and behavioural disorders	0.000	0.992	0.008
F18.7 Residual and late-onset psychotic disorder	0.000	0.992	0.008
F18.6 Amnesic syndrome	0.000	0.992	0.008
F18.5 Psychotic disorder	0.000	0.992	0.008
F18.4 Withdrawal state with delirium	0.000	0.992	0.008
F18.3 Withdrawal state	0.000	0.992	0.008
F18.2 Dependence syndrome	0.000	0.992	0.008
F18.1 Harmful use	0.000	0.992	0.008
F18.0 Acute intoxication	0.000	0.992	0.008
N39.4 Other specified urinary incontinence	0.000	0.992	0.008
F13.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
F13.8 Other mental and behavioural disorders	0.000	0.992	0.008
F13.7 Residual and late-onset psychotic disorder	0.000	0.992	0.008
F13.6 Amnesic syndrome	0.000	0.992	0.008
F13.5 Psychotic disorder	0.000	0.992	0.008
F13.4 Withdrawal state with delirium	0.000	0.992	0.008
F13.3 Withdrawal state	0.000	0.992	0.008
F13.1 Harmful use	0.000	0.992	0.008
F13.0 Acute intoxication	0.000	0.992	0.008
N07 Hereditary nephropathy, not elsewhere classified	0.007	0.992	0.002
N06 Isolated proteinuria with specified morphological lesion	0.007	0.992	0.002
N01 Rapidly progressive nephritic syndrome	0.007	0.992	0.002
N00 Acute nephritic syndrome	0.007	0.992	0.002
F17.9 Unspecified mental and behavioural disorder	0.000	0.992	0.008
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.007	0.992	0.001
F17.0 Acute intoxication	0.000	0.992	0.008
N27.9 Small kidney, unspecified	0.007	0.992	0.001
F13.2 Dependence syndrome	0.000	0.992	0.007
N04 Nephrotic syndrome	0.006	0.992	0.001
N25.1 Nephrogenic diabetes insipidus	0.006	0.993	0.001
N25.0 Renal osteodystrophy	0.006	0.993	0.001
M89 Other disorders of bone	0.007	0.993	0.000
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.001
N29.0 Late syphilis of kidney	0.006	0.993	0.001
N02 Recurrent and persistent haematuria	0.006	0.993	0.001
M87 Osteonecrosis	0.007	0.993	0.000
N27.1 Small kidney, bilateral	0.006	0.993	0.001
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.006	0.993	0.001
M89.8 Other specified disorders of bone	0.007	0.993	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.006	0.993	0.001
N05 Unspecified nephritic syndrome	0.005	0.994	0.002
N03 Chronic nephritic syndrome	0.004	0.994	0.002
M89.9 Disorder of bone, unspecified	0.006	0.994	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.994	0.006
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
N00.9 Unspecified	0.005	0.994	0.001
N00.8 Other	0.005	0.994	0.001
N00.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.001
N00.6 Dense deposit disease	0.005	0.994	0.001
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.001
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.001
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.001
N00.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.001
N00.1 Focal and segmental glomerular lesions	0.005	0.994	0.001
N00.0 Minor glomerular abnormality	0.005	0.994	0.001
N01.9 Unspecified	0.005	0.994	0.001
N01.8 Other	0.005	0.994	0.001
N01.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.001
N01.6 Dense deposit disease	0.005	0.994	0.001
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.001
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.001
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.001
N01.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.001
N01.1 Focal and segmental glomerular lesions	0.005	0.994	0.001
N01.0 Minor glomerular abnormality	0.005	0.994	0.001
N06.9 Unspecified	0.005	0.994	0.001
N06.8 Other	0.005	0.994	0.001
N06.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.001
N06.6 Dense deposit disease	0.005	0.994	0.001
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.001
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.001
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.001
N06.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.001
N06.1 Focal and segmental glomerular lesions	0.005	0.994	0.001
N06.0 Minor glomerular abnormality	0.005	0.994	0.001
N07.9 Unspecified	0.005	0.994	0.001
N07.8 Other	0.005	0.994	0.001
N07.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.001
N07.6 Dense deposit disease	0.005	0.994	0.001
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.001
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.001
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.001
N07.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.001
N07.1 Focal and segmental glomerular lesions	0.005	0.994	0.001
N07.0 Minor glomerular abnormality	0.005	0.994	0.001
N08 Glomerular disorders in diseases classified elsewhere	0.004	0.994	0.002
W19.4 Street and highway	0.000	0.994	0.006
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.006	0.994	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.006	0.994	0.000
M87.9 Osteonecrosis, unspecified	0.006	0.994	0.000
M88 Paget's disease of bone [osteitis deformans]	0.005	0.994	0.001
N26 Unspecified contracted kidney	0.004	0.994	0.002
N02.0 Minor glomerular abnormality	0.005	0.994	0.001
N04.8 Other	0.005	0.994	0.001
N04.7 Diffuse crescentic glomerulonephritis	0.005	0.994	0.001
N04.6 Dense deposit disease	0.005	0.994	0.001
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.994	0.001
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.994	0.001
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.994	0.001
N04.2 Diffuse membranous glomerulonephritis	0.005	0.994	0.001
N04.1 Focal and segmental glomerular lesions	0.005	0.994	0.001
N04.0 Minor glomerular abnormality	0.005	0.994	0.001
M89.3 Hypertrophy of bone	0.005	0.994	0.000
M87.8 Other osteonecrosis	0.005	0.994	0.000
M89.6 Osteopathy after poliomyelitis	0.005	0.994	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.005	0.994	0.000
M89.2 Other disorders of bone development and growth	0.005	0.994	0.000
M89.1 Epiphyseal arrest	0.005	0.994	0.000
N02.9 Unspecified	0.005	0.995	0.000
N02.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.001
N02.6 Dense deposit disease	0.005	0.995	0.001
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.001
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.001
N02.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.001
N02.1 Focal and segmental glomerular lesions	0.005	0.995	0.001
N28 Other disorders of kidney and ureter, not elsewhere classified	0.005	0.995	0.000
M87.3 Other secondary osteonecrosis	0.005	0.995	0.000
M87.2 Osteonecrosis due to previous trauma	0.005	0.995	0.000
M87.1 Osteonecrosis due to drugs	0.005	0.995	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.005	0.995	0.000
M89.88 Other specified disorders of bone (Other)	0.005	0.995	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.005	0.995	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.005	0.995	0.000
N02.2 Diffuse membranous glomerulonephritis	0.004	0.995	0.001
M89.84 Other specified disorders of bone (Hand)	0.005	0.995	0.000
R23.8 Other and unspecified skin changes	0.005	0.995	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.005	0.995	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.005	0.995	0.000
M89.83 Other specified disorders of bone (Forearm)	0.005	0.995	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.005	0.995	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.005	0.995	0.000
E04.1 Non-toxic single thyroid nodule	0.005	0.995	0.000
M94.8 Other specified disorders of cartilage	0.005	0.995	0.000
N04.9 Unspecified	0.004	0.995	0.001
M90 Osteopathies in diseases classified elsewhere	0.005	0.995	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.005	0.995	0.000
N05.1 Focal and segmental glomerular lesions	0.004	0.995	0.001
M89.5 Osteolysis	0.005	0.995	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.004	0.995	0.001
N05.6 Dense deposit disease	0.004	0.995	0.001
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.004	0.995	0.001
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.004	0.995	0.001
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.004	0.995	0.001
N05.0 Minor glomerular abnormality	0.004	0.995	0.001
N05.8 Other	0.004	0.995	0.001
M87.98 Osteonecrosis, unspecified (Other)	0.005	0.995	0.000
N03.8 Other	0.003	0.995	0.002
N03.7 Diffuse crescentic glomerulonephritis	0.003	0.995	0.002
N03.6 Dense deposit disease	0.003	0.995	0.002
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.995	0.002
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.995	0.002
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.995	0.002
N03.2 Diffuse membranous glomerulonephritis	0.003	0.995	0.002
N03.1 Focal and segmental glomerular lesions	0.003	0.995	0.002
N03.0 Minor glomerular abnormality	0.003	0.995	0.002
M89.99 Disorder of bone, unspecified (Site unspecified)	0.005	0.995	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.005	0.995	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.005	0.995	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.005	0.995	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.005	0.995	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.005	0.995	0.000
M89.98 Disorder of bone, unspecified (Other)	0.005	0.995	0.000
N08.8 Glomerular disorders in other diseases classified elsewhere	0.003	0.995	0.001
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.003	0.995	0.001
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.003	0.995	0.001
N08.1 Glomerular disorders in neoplastic diseases	0.003	0.995	0.001
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.003	0.995	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.005	0.995	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.004	0.995	0.000
W07.0 Home	0.000	0.995	0.005
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.004	0.995	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.004	0.996	0.000
N05.2 Diffuse membranous glomerulonephritis	0.003	0.996	0.001
M94.88 Other specified disorders of cartilage (Other)	0.004	0.996	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.004	0.996	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.004	0.996	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.004	0.996	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.004	0.996	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.004	0.996	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.004	0.996	0.000
M88.8 Paget's disease of other bones	0.004	0.996	0.001
M88.0 Paget's disease of skull	0.004	0.996	0.001
M89.37 Hypertrophy of bone (Ankle and foot)	0.004	0.996	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.004	0.996	0.000
M89.38 Hypertrophy of bone (Other)	0.004	0.996	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.004	0.996	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.004	0.996	0.000
M89.34 Hypertrophy of bone (Hand)	0.004	0.996	0.000
M89.33 Hypertrophy of bone (Forearm)	0.004	0.996	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.004	0.996	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.004	0.996	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.004	0.996	0.000
N08.5 Glomerular disorders in systemic connective tissue disorders	0.003	0.996	0.001
M87.89 Other osteonecrosis (Site unspecified)	0.004	0.996	0.000
M87.88 Other osteonecrosis (Other)	0.004	0.996	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.004	0.996	0.000
M87.86 Other osteonecrosis (Lower leg)	0.004	0.996	0.000
M87.84 Other osteonecrosis (Hand)	0.004	0.996	0.000
M87.83 Other osteonecrosis (Forearm)	0.004	0.996	0.000
M87.82 Other osteonecrosis (Upper arm)	0.004	0.996	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.004	0.996	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.004	0.996	0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.004	0.996	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations