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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4294047
log Bayes Factor = 18.3213
Chromosome 6   position 31,101,583  (GRCh37) Explore rs4294047 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
J45.9 Asthma, unspecified
0.000 0.101 0.899
K90 Intestinal malabsorption
0.000 0.255 0.745
R31 Unspecified haematuria
0.697 0.303 0.000
J45 Asthma
0.004 0.305 0.691
J45.0 Predominantly allergic asthma
0.001 0.368 0.631
K90.9 Intestinal malabsorption, unspecified
0.000 0.412 0.588
E10.9 Without complications
0.000 0.412 0.588
K90-K93 Other diseases of the digestive system
0.000 0.423 0.577
E10 Insulin-dependent diabetes mellitus
0.000 0.444 0.556
K92 Other diseases of digestive system
0.000 0.458 0.542
K90.8 Other intestinal malabsorption
0.000 0.466 0.534
K90.3 Pancreatic steatorrhoea
0.000 0.466 0.534
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.466 0.534
K90.1 Tropical sprue
0.000 0.466 0.534
K92.2 Gastro-intestinal haemorrhage, unspecified
0.000 0.476 0.524
J45.8 Mixed asthma
0.003 0.502 0.495
J45.1 Nonallergic asthma
0.003 0.502 0.495
E10.3 With ophthalmic complications
0.000 0.509 0.491
K92.1 Melaena
0.000 0.516 0.484
E10.1 With ketoacidosis
0.000 0.516 0.484
E10.4 With neurological complications
0.000 0.553 0.447
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.562 0.437
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.583 0.417
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.586 0.414
E10.2 With renal complications
0.000 0.592 0.408
E10.5 With peripheral circulatory complications
0.000 0.594 0.406
E03 Other hypothyroidism
0.392 0.600 0.007
E10.8 With unspecified complications
0.000 0.601 0.399
E10.7 With multiple complications
0.000 0.601 0.399
E10.6 With other specified complications
0.000 0.601 0.399
E10.0 With coma
0.000 0.601 0.399
K91.3 Postoperative intestinal obstruction
0.000 0.616 0.384
K92.8 Other specified diseases of digestive system
0.000 0.632 0.368
E10-E14 Diabetes mellitus
0.002 0.638 0.360
K92.9 Disease of digestive system, unspecified
0.000 0.650 0.350
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.663 0.337
E14 Unspecified diabetes mellitus
0.000 0.669 0.330
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.701 0.299
K91.5 Postcholecystectomy syndrome
0.000 0.701 0.299
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.701 0.299
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.703 0.297
K93.1 Megacolon in Chagas' disease
0.000 0.703 0.297
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.703 0.297
E14.9 Without complications
0.000 0.705 0.295
E03.5 Myxoedema coma
0.281 0.713 0.005
E03.4 Atrophy of thyroid (acquired)
0.281 0.713 0.005
E03.3 Postinfectious hypothyroidism
0.281 0.713 0.005
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.281 0.713 0.005
E03.1 Congenital hypothyroidism without goitre
0.281 0.713 0.005
E03.0 Congenital hypothyroidism with diffuse goitre
0.281 0.713 0.005
E13 Other specified diabetes mellitus
0.001 0.725 0.274
E14.3 With ophthalmic complications
0.000 0.728 0.272
E12 Malnutrition-related diabetes mellitus
0.001 0.741 0.258
K91.1 Postgastric surgery syndromes
0.000 0.751 0.249
E14.8 With unspecified complications
0.000 0.763 0.237
E14.7 With multiple complications
0.000 0.763 0.237
E14.6 With other specified complications
0.000 0.763 0.237
E14.5 With peripheral circulatory complications
0.000 0.763 0.237
E14.4 With neurological complications
0.000 0.763 0.237
E14.2 Withrenal complications
0.000 0.763 0.237
E14.1 With ketoacidosis
0.000 0.763 0.237
E14.0 With coma
0.000 0.763 0.237
J40-J47 Chronic lower respiratory diseases
0.042 0.772 0.186
E03.8 Other specified hypothyroidism
0.219 0.775 0.006
K91.4 Colostomy and enterostomy malfunction
0.000 0.785 0.214
E13.9 Without complications
0.001 0.787 0.212
J43 Emphysema
0.019 0.797 0.184
E13.8 With unspecified complications
0.001 0.803 0.197
E13.7 With multiple complications
0.001 0.803 0.197
E13.6 With other specified complications
0.001 0.803 0.197
E13.5 With peripheral circulatory complications
0.001 0.803 0.197
E13.4 With neurological complications
0.001 0.803 0.197
E13.3 With ophthalmic complications
0.001 0.803 0.197
E13.2 With renal complications
0.001 0.803 0.197
E13.1 With ketoacidosis
0.001 0.803 0.197
E13.0 With coma
0.001 0.803 0.197
E12.9 Without complications
0.001 0.814 0.185
E12.8 With unspecified complications
0.001 0.814 0.185
E12.7 With multiple complications
0.001 0.814 0.185
E12.6 With other specified complications
0.001 0.814 0.185
E12.5 With peripheral circulatory complications
0.001 0.814 0.185
E12.4 With neurological complications
0.001 0.814 0.185
E12.3 With ophthalmic complications
0.001 0.814 0.185
E12.2 With renal complications
0.001 0.814 0.185
E12.1 With ketoacidosis
0.001 0.814 0.185
E12.0 With coma
0.001 0.814 0.185
J43.9 Emphysema, unspecified
0.001 0.815 0.184
J46 Status asthmaticus
0.015 0.819 0.165
E11 Non-insulin-dependent diabetes mellitus
0.000 0.826 0.174
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.828 0.172
K92.0 Haematemesis
0.000 0.832 0.167
J41 Simple and mucopurulent chronic bronchitis
0.030 0.836 0.134
E11.1 With ketoacidosis
0.000 0.849 0.151
E11.4 With neurological complications
0.000 0.851 0.149
J43.8 Other emphysema
0.014 0.854 0.132
J43.1 Panlobular emphysema
0.014 0.854 0.132
J43.0 MacLeod's syndrome
0.014 0.854 0.132
E11.5 With peripheral circulatory complications
0.000 0.860 0.140
J43.2 Centrilobular emphysema
0.015 0.867 0.118
E00-E07 Disorders of thyroid gland
0.115 0.873 0.012
E78.0 Pure hypercholesterolaemia
0.126 0.874 0.000
E11.7 With multiple complications
0.000 0.875 0.125
E11.2 With renal complications
0.000 0.879 0.121
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.022 0.882 0.096
J41.1 Mucopurulent chronic bronchitis
0.022 0.882 0.096
J41.0 Simple chronic bronchitis
0.022 0.882 0.096
D50.8 Other iron deficiency anaemias
0.000 0.883 0.117
E11.8 With unspecified complications
0.000 0.885 0.115
E11.6 With other specified complications
0.000 0.894 0.105
J47 Bronchiectasis
0.097 0.900 0.003
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.900 0.100
D50 Iron deficiency anaemia
0.000 0.901 0.099
E11.0 With coma
0.000 0.901 0.098
E06 Thyroiditis
0.092 0.901 0.006
E11.3 With ophthalmic complications
0.000 0.902 0.098
J42 Unspecified chronic bronchitis
0.039 0.902 0.059
D51 Vitamin B12 deficiency anaemia
0.000 0.903 0.097
D50-D53 Nutritional anaemias
0.000 0.905 0.095
E07 Other disorders of thyroid
0.085 0.908 0.007
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.082 0.909 0.009
E00 Congenital iodine-deficiency syndrome
0.082 0.909 0.009
E02 Subclinical iodine-deficiency hypothyroidism
0.082 0.909 0.009
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.922 0.078
Chapter IV Endocrine, nutritional and metabolic diseases
0.037 0.923 0.040
E06.9 Thyroiditis, unspecified
0.073 0.923 0.004
E06.3 Autoimmune thyroiditis
0.071 0.926 0.003
D50.1 Sideropenic dysphagia
0.000 0.928 0.071
E06.5 Other chronic thyroiditis
0.066 0.929 0.005
E06.4 Drug-induced thyroiditis
0.066 0.929 0.005
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.066 0.929 0.005
E06.1 Subacute thyroiditis
0.066 0.929 0.005
E06.0 Acute thyroiditis
0.066 0.929 0.005
D50.9 Iron deficiency anaemia, unspecified
0.000 0.930 0.070
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.930 0.070
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.930 0.070
D51.2 Transcobalamin II deficiency
0.000 0.930 0.070
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.930 0.070
D53 Other nutritional anaemias
0.000 0.932 0.068
E07.9 Disorder of thyroid, unspecified
0.063 0.933 0.003
J40 Bronchitis, not specified as acute or chronic
0.043 0.933 0.023
E07.8 Other specified disorders of thyroid
0.061 0.934 0.005
E07.1 Dyshormogenetic goitre
0.061 0.934 0.005
E07.0 Hypersecretion of calcitonin
0.061 0.934 0.005
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.059 0.934 0.006
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.059 0.934 0.006
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.059 0.934 0.006
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.059 0.934 0.006
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.059 0.934 0.006
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.059 0.934 0.006
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.059 0.934 0.006
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.059 0.934 0.006
D52 Folate deficiency anaemia
0.000 0.937 0.062
E04 Other non-toxic goitre
0.054 0.942 0.004
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.056 0.943 0.001
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.021 0.946 0.033
Chapter X Diseases of the respiratory system
0.000 0.946 0.054
E40-E46 Malnutrition
0.027 0.947 0.026
E05 Thyrotoxicosis [hyperthyroidism]
0.042 0.949 0.009
J95-J99 Other diseases of the respiratory system
0.000 0.949 0.050
E50-E64 Other nutritional deficiencies
0.020 0.950 0.030
D53.9 Nutritional anaemia, unspecified
0.000 0.951 0.049
D53.8 Other specified nutritional anaemias
0.000 0.951 0.049
D53.2 Scorbutic anaemia
0.000 0.951 0.049
D53.1 Other megaloblastic anaemias, not elsewhere classified
0.000 0.951 0.049
D53.0 Protein deficiency anaemia
0.000 0.951 0.049
J80-J84 Other respiratory diseases principally affecting the interstitium
0.000 0.952 0.048
J98 Other respiratory disorders
0.000 0.952 0.048
J84 Other interstitial pulmonary diseases
0.000 0.953 0.047
J98.4 Other disorders of lung
0.000 0.953 0.047
E70-E90 Metabolic disorders
0.036 0.954 0.011
E65-E68 Obesity and other hyperalimentation
0.031 0.954 0.014
D52.8 Other folate deficiency anaemias
0.000 0.955 0.045
D52.1 Drug-induced folate deficiency anaemia
0.000 0.955 0.045
D52.0 Dietary folate deficiency anaemia
0.000 0.955 0.045
J90-J94 Other diseases of pleura
0.000 0.955 0.045
E20-E35 Disorders of other endocrine glands
0.011 0.956 0.033
J84.1 Other interstitial pulmonary diseases with fibrosis
0.000 0.956 0.044
E78.4 Other hyperlipidaemia
0.043 0.956 0.001
J33.0 Polyp of nasal cavity
0.000 0.956 0.044
E04.0 Non-toxic diffuse goitre
0.040 0.957 0.003
J93 Pneumothorax
0.000 0.957 0.043
E78.8 Other disorders of lipoprotein metabolism
0.042 0.958 0.001
E78.9 Disorder of lipoprotein metabolism, unspecified
0.041 0.958 0.001
E04.8 Other specified non-toxic goitre
0.039 0.958 0.003
J95 Postprocedural respiratory disorders, not elsewhere classified
0.000 0.958 0.041
J93.9 Pneumothorax, unspecified
0.000 0.959 0.041
J84.9 Interstitial pulmonary disease, unspecified
0.000 0.959 0.041
E78.6 Lipoprotein deficiency
0.040 0.959 0.001
E78.3 Hyperchylomicronaemia
0.040 0.959 0.001
E78.1 Pure hyperglyceridaemia
0.040 0.959 0.001
D52.9 Folate deficiency anaemia, unspecified
0.000 0.960 0.039
E15 Nondiabetic hypoglycaemic coma
0.016 0.961 0.024
J98.9 Respiratory disorder, unspecified
0.000 0.961 0.039
E44 Protein-energy malnutrition of moderate and mild degree
0.019 0.962 0.019
E45 Retarded development following protein-energy malnutrition
0.019 0.962 0.019
E43 Unspecified severe protein-energy malnutrition
0.019 0.962 0.019
E42 Marasmic kwashiorkor
0.019 0.962 0.019
E41 Nutritional marasmus
0.019 0.962 0.019
E40 Kwashiorkor
0.019 0.962 0.019
E16 Other disorders of pancreatic internal secretion
0.010 0.962 0.028
E78.2 Mixed hyperlipidaemia
0.037 0.962 0.001
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.962 0.038
E04.9 Non-toxic goitre, unspecified
0.035 0.963 0.002
E05.8 Other thyrotoxicosis
0.030 0.963 0.006
E05.5 Thyroid crisis or storm
0.030 0.963 0.006
E05.4 Thyrotoxicosis factitia
0.030 0.963 0.006
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.030 0.963 0.006
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.030 0.963 0.006
J96 Respiratory failure, not elsewhere classified
0.000 0.963 0.036
J98.8 Other specified respiratory disorders
0.000 0.964 0.036
E64 Sequelae of malnutrition and other nutritional deficiencies
0.015 0.964 0.022
E63 Other nutritional deficiencies
0.015 0.964 0.022
E56 Other vitamin deficiencies
0.015 0.964 0.022
E51 Thiamine deficiency
0.015 0.964 0.022
E50 Vitamin A deficiency
0.015 0.964 0.022
E60 Dietary zinc deficiency
0.015 0.964 0.022
E59 Dietary selenium deficiency
0.015 0.964 0.022
E58 Dietary calcium deficiency
0.015 0.964 0.022
E54 Ascorbic acid deficiency
0.015 0.964 0.022
E52 Niacin deficiency [pellagra]
0.015 0.964 0.022
J60-J70 Lung diseases due to external agents
0.000 0.964 0.036
E29 Testicular dysfunction
0.006 0.964 0.030
E46 Unspecified protein-energy malnutrition
0.020 0.964 0.016
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.030 0.964 0.006
J91 Pleural effusion in conditions classified elsewhere
0.000 0.964 0.036
E83 Disorders of mineral metabolism
0.027 0.964 0.008
J93.8 Other pneumothorax
0.000 0.965 0.035
E55 Vitamin D deficiency
0.011 0.965 0.024
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.965 0.034
J98.6 Disorders of diaphragm
0.000 0.966 0.034
J98.3 Compensatory emphysema
0.000 0.966 0.034
J98.2 Interstitial emphysema
0.000 0.966 0.034
E65 Localised adiposity
0.027 0.966 0.007
E80 Disorders of porphyrin and bilirubin metabolism
0.028 0.966 0.006
E53 Deficiency of other B group vitamins
0.010 0.966 0.024
J84.0 Alveolar and parietoalveolar conditions
0.000 0.966 0.034
J84.8 Other specified interstitial pulmonary diseases
0.000 0.966 0.034
J80 Adult respiratory distress syndrome
0.000 0.966 0.034
J94 Other pleural conditions
0.000 0.966 0.034
J95.8 Other postprocedural respiratory disorders
0.000 0.966 0.034
J99 Respiratory disorders in diseases classified elsewhere
0.000 0.966 0.033
E84 Cystic fibrosis
0.026 0.966 0.008
E79 Disorders of purine and pyrimidine metabolism
0.026 0.966 0.008
E77 Disorders of glycoprotein metabolism
0.026 0.966 0.008
E76 Disorders of glycosaminoglycan metabolism
0.026 0.966 0.008
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.026 0.966 0.008
E72 Other disorders of amino-acid metabolism
0.026 0.966 0.008
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.026 0.966 0.008
E70 Disorders of aromatic amino-acid metabolism
0.026 0.966 0.008
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.026 0.966 0.008
E67 Other hyperalimentation
0.023 0.967 0.010
E68 Sequelae of hyperalimentation
0.023 0.967 0.010
E74 Other disorders of carbohydrate metabolism
0.025 0.967 0.008
E61 Deficiency of other nutrient elements
0.016 0.967 0.016
E34 Other endocrine disorders
0.008 0.967 0.025
E22 Hyperfunction of pituitary gland
0.006 0.967 0.027
E23 Hypofunction and other disorders of pituitary gland
0.006 0.968 0.026
J82 Pulmonary eosinophilia, not elsewhere classified
0.000 0.968 0.032
E35 Disorders of endocrine glands in diseases classified elsewhere
0.008 0.968 0.024
E32 Diseases of thymus
0.008 0.968 0.024
E31 Polyglandular dysfunction
0.008 0.968 0.024
E30 Disorders of puberty, not elsewhere classified
0.008 0.968 0.024
E25 Adrenogenital disorders
0.008 0.968 0.024
E20 Hypoparathyroidism
0.008 0.968 0.024
J98.1 Pulmonary collapse
0.000 0.968 0.032
J95.0 Tracheostomy malfunction
0.000 0.968 0.032
E04.2 Non-toxic multinodular goitre
0.030 0.968 0.002
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.026 0.969 0.005
J93.0 Spontaneous tension pneumothorax
0.000 0.969 0.031
E04.1 Non-toxic single thyroid nodule
0.028 0.969 0.003
E28 Ovarian dysfunction
0.007 0.969 0.023
E27 Other disorders of adrenal gland
0.006 0.969 0.025
J92 Pleural plaque
0.000 0.969 0.031
E73 Lactose intolerance
0.022 0.969 0.009
E85 Amyloidosis
0.022 0.969 0.008
E24 Cushing's syndrome
0.009 0.969 0.022
J33 Nasal polyp
0.000 0.969 0.031
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.970 0.030
E26 Hyperaldosteronism
0.009 0.970 0.022
J93.1 Other spontaneous pneumothorax
0.000 0.970 0.030
J95.9 Postprocedural respiratory disorder, unspecified
0.000 0.970 0.030
J95.5 Postprocedural subglottic stenosis
0.000 0.970 0.030
J95.4 Mendelson's syndrome
0.000 0.970 0.030
J95.3 Chronic pulmonary insufficiency following surgery
0.000 0.970 0.030
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.000 0.970 0.030
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.000 0.970 0.030
E29.1 Testicular hypofunction
0.002 0.970 0.028
D12.0 Caecum
0.029 0.971 0.000
E88 Other metabolic disorders
0.019 0.971 0.010
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.972 0.028
J94.8 Other specified pleural conditions
0.000 0.972 0.028
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.000 0.972 0.028
E44.1 Mild protein-energy malnutrition
0.014 0.972 0.014
E44.0 Moderate protein-energy malnutrition
0.014 0.972 0.014
E16.9 Disorder of pancreatic internal secretion, unspecified
0.007 0.972 0.020
E16.8 Other specified disorders of pancreatic internal secretion
0.007 0.972 0.020
E16.4 Abnormal secretion of gastrin
0.007 0.972 0.020
E16.3 Increased secretion of glucagon
0.007 0.972 0.020
E16.1 Other hypoglycaemia
0.007 0.972 0.020
E16.0 Drug-induced hypoglycaemia without coma
0.007 0.972 0.020
E83.4 Disorders of magnesium metabolism
0.025 0.972 0.002
E16.2 Hypoglycaemia, unspecified
0.002 0.974 0.024
J96.9 Respiratory failure, unspecified
0.000 0.974 0.026
J96.1 Chronic respiratory failure
0.000 0.974 0.026
J96.0 Acute respiratory failure
0.000 0.974 0.026
E66 Obesity
0.022 0.974 0.004
J81 Pulmonary oedema
0.000 0.974 0.026
J44 Other chronic obstructive pulmonary disease
0.005 0.974 0.021
E50.9 Vitamin A deficiency, unspecified
0.011 0.974 0.016
E50.8 Other manifestations of vitamin A deficiency
0.011 0.974 0.016
E50.7 Other ocular manifestations of vitamin A deficiency
0.011 0.974 0.016
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.011 0.974 0.016
E50.5 Vitamin A deficiency with night blindness
0.011 0.974 0.016
E50.4 Vitamin A deficiency with keratomalacia
0.011 0.974 0.016
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.011 0.974 0.016
E50.2 Vitamin A deficiency with corneal xerosis
0.011 0.974 0.016
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.011 0.974 0.016
E50.0 Vitamin A deficiency with conjunctival xerosis
0.011 0.974 0.016
E51.9 Thiamine deficiency, unspecified
0.011 0.974 0.016
E51.8 Other manifestations of thiamine deficiency
0.011 0.974 0.016
E51.2 Wernicke's encephalopathy
0.011 0.974 0.016
E51.1 Beriberi
0.011 0.974 0.016
E56.9 Vitamin deficiency, unspecified
0.011 0.974 0.016
E56.8 Deficiency of other vitamins
0.011 0.974 0.016
E56.1 Deficiency of vitamin K
0.011 0.974 0.016
E56.0 Deficiency of vitamin E
0.011 0.974 0.016
E63.9 Nutritional deficiency, unspecified
0.011 0.974 0.016
E63.8 Other specified nutritional deficiencies
0.011 0.974 0.016
E63.1 Imbalance of constituents of food intake
0.011 0.974 0.016
E63.0 Essential fatty acid [EFA] deficiency
0.011 0.974 0.016
E64.9 Sequelae of unspecified nutritional deficiency
0.011 0.974 0.016
E64.8 Sequelae of other nutritional deficiencies
0.011 0.974 0.016
E64.3 Sequelae of rickets
0.011 0.974 0.016
E64.2 Sequelae of vitamin C deficiency
0.011 0.974 0.016
E64.1 Sequelae of vitamin A deficiency
0.011 0.974 0.016
E64.0 Sequelae of protein-energy malnutrition
0.011 0.974 0.016
J00-J06 Acute upper respiratory infections
0.000 0.974 0.026
J70 Respiratory conditions due to other external agents
0.000 0.974 0.026
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.000 0.974 0.026
J66 Airway disease due to specific organic dust
0.000 0.974 0.026
J63 Pneumoconiosis due to other inorganic dusts
0.000 0.974 0.026
J62 Pneumoconiosis due to dust containing silica
0.000 0.974 0.026
J65 Pneumoconiosis associated with tuberculosis
0.000 0.974 0.026
J64 Unspecified pneumoconiosis
0.000 0.974 0.026
J60 Coalworker's pneumoconiosis
0.000 0.974 0.026
E29.9 Testicular dysfunction, unspecified
0.005 0.974 0.022
E29.8 Other testicular dysfunction
0.005 0.974 0.022
E29.0 Testicular hyperfunction
0.005 0.974 0.022
J92.9 Pleural plaque without asbestos
0.000 0.974 0.026
E83.9 Disorder of mineral metabolism, unspecified
0.020 0.974 0.006
E83.8 Other disorders of mineral metabolism
0.020 0.974 0.006
E83.2 Disorders of zinc metabolism
0.020 0.974 0.006
E83.0 Disorders of copper metabolism
0.020 0.974 0.006
E83.3 Disorders of phosphorus metabolism
0.021 0.974 0.005
J99.8 Respiratory disorders in other diseases classified elsewhere
0.000 0.974 0.025
E55.0 Rickets, active
0.008 0.975 0.017
E05.9 Thyrotoxicosis, unspecified
0.023 0.975 0.003
E80.4 Gilbert's syndrome
0.023 0.975 0.003
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.003 0.975 0.022
J85 Abscess of lung and mediastinum
0.000 0.975 0.025
E80.7 Disorder of bilirubin metabolism, unspecified
0.020 0.975 0.004
E80.6 Other disorders of bilirubin metabolism
0.020 0.975 0.004
E80.5 Crigler-Najjar syndrome
0.020 0.975 0.004
E80.3 Defects of catalase and peroxydase
0.020 0.975 0.004
E80.2 Other porphyria
0.020 0.975 0.004
E80.1 Porphyria cutanea tarda
0.020 0.975 0.004
E80.0 Hereditary erythropoietic porphyria
0.020 0.975 0.004
E53.9 Vitamin B deficiency, unspecified
0.007 0.975 0.017
E53.1 Pyridoxine deficiency
0.007 0.975 0.017
E53.0 Riboflavin deficiency
0.007 0.975 0.017
E89.4 Postprocedural ovarian failure
0.021 0.976 0.003
J94.9 Pleural condition, unspecified
0.000 0.976 0.024
J94.1 Fibrothorax
0.000 0.976 0.024
J94.0 Chylous effusion
0.000 0.976 0.024
J30-J39 Other diseases of upper respiratory tract
0.000 0.976 0.024
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.019 0.976 0.006
E70.8 Other disorders of aromatic amino-acid metabolism
0.019 0.976 0.006
E70.3 Albinism
0.019 0.976 0.006
E70.2 Disorders of tyrosine metabolism
0.019 0.976 0.006
E70.1 Other hyperphenylalaninaemias
0.019 0.976 0.006
E70.0 Classical phenylketonuria
0.019 0.976 0.006
E71.3 Disorders of fatty-acid metabolism
0.019 0.976 0.006
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.019 0.976 0.006
E71.1 Other disorders of branched-chain amino-acid metabolism
0.019 0.976 0.006
E71.0 Maple-syrup-urine disease
0.019 0.976 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.019 0.976 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.019 0.976 0.006
E72.5 Disorders of glycine metabolism
0.019 0.976 0.006
E72.4 Disorders of ornithine metabolism
0.019 0.976 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.019 0.976 0.006
E72.2 Disorders of urea cycle metabolism
0.019 0.976 0.006
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.019 0.976 0.006
E72.0 Disorders of amino-acid transport
0.019 0.976 0.006
E75.6 Lipid storage disorder, unspecified
0.019 0.976 0.006
E75.5 Other lipid storage disorders
0.019 0.976 0.006
E75.4 Neuronal ceroid lipofuscinosis
0.019 0.976 0.006
E75.3 Sphingolipidosis, unspecified
0.019 0.976 0.006
E75.2 Other sphingolipidosis
0.019 0.976 0.006
E75.1 Other gangliosidosis
0.019 0.976 0.006
E75.0 GM2 gangliosidosis
0.019 0.976 0.006
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.019 0.976 0.006
E76.8 Other disorders of glucosaminoglycan metabolism
0.019 0.976 0.006
E76.3 Mucopolysaccharidosis, unspecified
0.019 0.976 0.006
E76.2 Other mucopolysaccharidoses
0.019 0.976 0.006
E76.1 Mucopolysaccharidosis, type II
0.019 0.976 0.006
E76.0 Mucopolysaccharidosis, type I
0.019 0.976 0.006
E77.9 Disorder of glycoprotein metabolism, unspecified
0.019 0.976 0.006
E77.8 Other disorders of glycoprotein metabolism
0.019 0.976 0.006
E77.1 Defects in glycoprotein degradation
0.019 0.976 0.006
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.019 0.976 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.019 0.976 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.019 0.976 0.006
E79.1 Lesch-Nyhan syndrome
0.019 0.976 0.006
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.019 0.976 0.006
E84.9 Cystic fibrosis, unspecified
0.019 0.976 0.006
E84.8 Cystic fibrosis with other manifestations
0.019 0.976 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.019 0.976 0.006
E84.0 Cystic fibrosis with pulmonary manifestations
0.019 0.976 0.006
E34.9 Endocrine disorder, unspecified
0.005 0.976 0.019
E27.1 Primary adrenocortical insufficiency
0.003 0.976 0.021
E55.9 Vitamin D deficiency, unspecified
0.005 0.976 0.019
E67.8 Other specified hyperalimentation
0.016 0.976 0.008
E67.3 Hypervitaminosis D
0.016 0.976 0.008
E67.2 Megavitamin-B6 syndrome
0.016 0.976 0.008
E67.1 Hypercarotenaemia
0.016 0.976 0.008
E67.0 Hypervitaminosis A
0.016 0.976 0.008
E23.0 Hypopituitarism
0.003 0.976 0.021
E74.9 Disorder of carbohydrate metabolism, unspecified
0.018 0.976 0.006
E74.8 Other specified disorders of carbohydrate metabolism
0.018 0.976 0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.018 0.976 0.006
E74.2 Disorders of galactose metabolism
0.018 0.976 0.006
E74.1 Disorders of fructose metabolism
0.018 0.976 0.006
E74.0 Glycogen storage disease
0.018 0.976 0.006
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.024 0.976 0.000
E23.2 Diabetes insipidus
0.004 0.976 0.020
E61.9 Deficiency of nutrient element, unspecified
0.012 0.976 0.012
E61.8 Deficiency of other specified nutrient elements
0.012 0.976 0.012
E61.7 Deficiency of multiple nutrient elements
0.012 0.976 0.012
E61.6 Vanadium deficiency
0.012 0.976 0.012
E61.5 Molybdenum deficiency
0.012 0.976 0.012
E61.4 Chromium deficiency
0.012 0.976 0.012
E61.3 Manganese deficiency
0.012 0.976 0.012
E61.0 Copper deficiency
0.012 0.976 0.012
E22.9 Hyperfunction of pituitary gland, unspecified
0.004 0.976 0.019
E22.8 Other hyperfunction of pituitary gland
0.004 0.976 0.019
E34.8 Other specified endocrine disorders
0.006 0.976 0.018
E34.5 Androgen resistance syndrome
0.006 0.976 0.018
E34.4 Constitutional tall stature
0.006 0.976 0.018
E34.3 Short stature, not elsewhere classified
0.006 0.976 0.018
E34.2 Ectopic hormone secretion, not elsewhere classified
0.006 0.976 0.018
E34.1 Other hypersecretion of intestinal hormones
0.006 0.976 0.018
E34.0 Carcinoid syndrome
0.006 0.976 0.018
J69 Pneumonitis due to solids and liquids
0.000 0.976 0.023
E22.1 Hyperprolactinaemia
0.004 0.977 0.019
E23.7 Disorder of pituitary gland, unspecified
0.004 0.977 0.019
E23.6 Other disorders of pituitary gland
0.004 0.977 0.019
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.004 0.977 0.019
E23.1 Drug-induced hypopituitarism
0.004 0.977 0.019
E61.2 Magnesium deficiency
0.013 0.977 0.010
D86.9 Sarcoidosis, unspecified
0.000 0.977 0.023
E20.9 Hypoparathyroidism, unspecified
0.006 0.977 0.017
E20.8 Other hypoparathyroidism
0.006 0.977 0.017
E20.1 Pseudohypoparathyroidism
0.006 0.977 0.017
E20.0 Idiopathic hypoparathyroidism
0.006 0.977 0.017
E25.9 Adrenogenital disorder, unspecified
0.006 0.977 0.017
E25.8 Other adrenogenital disorders
0.006 0.977 0.017
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.006 0.977 0.017
E30.9 Disorder of puberty, unspecified
0.006 0.977 0.017
E30.8 Other disorders of puberty
0.006 0.977 0.017
E30.1 Precocious puberty
0.006 0.977 0.017
E30.0 Delayed puberty
0.006 0.977 0.017
E31.9 Polyglandular dysfunction, unspecified
0.006 0.977 0.017
E31.8 Other polyglandular dysfunction
0.006 0.977 0.017
E31.1 Polyglandular hyperfunction
0.006 0.977 0.017
E31.0 Autoimmune polyglandular failure
0.006 0.977 0.017
E32.9 Disease of thymus, unspecified
0.006 0.977 0.017
E32.8 Other diseases of thymus
0.006 0.977 0.017
E32.1 Abscess of thymus
0.006 0.977 0.017
E32.0 Persistent hyperplasia of thymus
0.006 0.977 0.017
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.006 0.977 0.017
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.006 0.977 0.017
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.006 0.977 0.017
J67 Hypersensitivity pneumonitis due to organic dust
0.000 0.977 0.023
E22.0 Acromegaly and pituitary gigantism
0.004 0.977 0.019
E74.3 Other disorders of intestinal carbohydrate absorption
0.017 0.977 0.006
E83.5 Disorders of calcium metabolism
0.021 0.977 0.002
D86 Sarcoidosis
0.000 0.977 0.023
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.019 0.977 0.004
E89.8 Other postprocedural endocrine and metabolic disorders
0.019 0.977 0.004
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.019 0.977 0.004
E89.5 Postprocedural testicular hypofunction
0.019 0.977 0.004
E89.1 Postprocedural hypoinsulinaemia
0.019 0.977 0.004
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.010 0.978 0.013
E28.9 Ovarian dysfunction, unspecified
0.006 0.978 0.017
E28.8 Other ovarian dysfunction
0.006 0.978 0.017
E28.3 Primary ovarian failure
0.006 0.978 0.017
E28.1 Androgen excess
0.006 0.978 0.017
E28.0 Oestrogen excess
0.006 0.978 0.017

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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