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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs429853
log Bayes Factor = 153.055
Chromosome 6   position 32,187,202  (GRCh37) Explore rs429853 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E11.9 Without complications
1.000 0.000 0.000
K90.0 Coeliac disease
1.000 0.000 0.000
L40.9 Psoriasis, unspecified
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
G35 Multiple sclerosis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
L40 Psoriasis
1.000 0.000 0.000
L40.5 Arthropathic psoriasis
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
E20-E35 Disorders of other endocrine glands
0.999 0.001 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.999 0.001 0.000
E10.3 With ophthalmic complications
0.998 0.002 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.988 0.012 0.000
E27 Other disorders of adrenal gland
0.987 0.013 0.000
E14 Unspecified diabetes mellitus
0.981 0.019 0.000
E16 Other disorders of pancreatic internal secretion
0.980 0.020 0.000
E10.1 With ketoacidosis
0.974 0.026 0.000
E16.2 Hypoglycaemia, unspecified
0.965 0.035 0.000
E14.3 With ophthalmic complications
0.964 0.036 0.000
E11.3 With ophthalmic complications
0.963 0.037 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.952 0.048 0.000
E13 Other specified diabetes mellitus
0.951 0.049 0.000
E27.1 Primary adrenocortical insufficiency
0.933 0.067 0.000
E21.3 Hyperparathyroidism, unspecified
0.922 0.078 0.000
E13.9 Without complications
0.920 0.080 0.000
K90 Intestinal malabsorption
0.902 0.098 0.000
L40.0 Psoriasis vulgaris
0.897 0.103 0.000
E11.5 With peripheral circulatory complications
0.890 0.110 0.000
E24 Cushing's syndrome
0.887 0.113 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.887 0.113 0.000
E11.2 With renal complications
0.886 0.114 0.000
E23 Hypofunction and other disorders of pituitary gland
0.875 0.125 0.000
E14.8 With unspecified complications
0.865 0.135 0.000
K90.9 Intestinal malabsorption, unspecified
0.862 0.138 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.014 0.138 0.848
E10.2 With renal complications
0.854 0.146 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.853 0.147 0.000
E11.1 With ketoacidosis
0.844 0.156 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.841 0.159 0.000
L40.4 Guttate psoriasis
0.837 0.163 0.000
E14.5 With peripheral circulatory complications
0.823 0.177 0.000
L40-L45 Papulosquamous disorders
0.821 0.179 0.000
G37 Other demyelinating diseases of central nervous system
0.004 0.184 0.813
E10.5 With peripheral circulatory complications
0.814 0.186 0.000
E11.7 With multiple complications
0.806 0.194 0.000
E24.2 Drug-induced Cushing's syndrome
0.799 0.201 0.000
L40.1 Generalised pustular psoriasis
0.797 0.203 0.000
E28 Ovarian dysfunction
0.795 0.204 0.000
E20 Hypoparathyroidism
0.793 0.207 0.000
E10.7 With multiple complications
0.788 0.212 0.000
E10.6 With other specified complications
0.788 0.212 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.000 0.218 0.781
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.771 0.229 0.000
E10.0 With coma
0.770 0.230 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.767 0.233 0.000
E29 Testicular dysfunction
0.757 0.243 0.000
E23.7 Disorder of pituitary gland, unspecified
0.753 0.247 0.000
E11.6 With other specified complications
0.753 0.247 0.000
E31 Polyglandular dysfunction
0.750 0.250 0.000
E10.8 With unspecified complications
0.748 0.252 0.000
E16.1 Other hypoglycaemia
0.747 0.253 0.000
E27.2 Addisonian crisis
0.747 0.253 0.000
E27.9 Disorder of adrenal gland, unspecified
0.746 0.253 0.000
E23.2 Diabetes insipidus
0.741 0.259 0.000
L43 Lichen planus
0.739 0.261 0.000
E23.6 Other disorders of pituitary gland
0.736 0.264 0.000
E14.1 With ketoacidosis
0.733 0.267 0.000
E24.0 Pituitary-dependent Cushing's disease
0.727 0.273 0.000
E10.4 With neurological complications
0.725 0.275 0.000
E21.4 Other specified disorders of parathyroid gland
0.721 0.279 0.000
E40-E46 Malnutrition
0.721 0.279 0.000
L40.8 Other psoriasis
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
L40.2 Acrodermatitis continua
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.717 0.283 0.000
E32 Diseases of thymus
0.717 0.283 0.000
E30 Disorders of puberty, not elsewhere classified
0.717 0.283 0.000
E14.4 With neurological complications
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.708 0.291 0.000
L40.3 Pustulosis palmaris et plantaris
0.708 0.292 0.000
E27.5 Adrenomedullary hyperfunction
0.708 0.292 0.000
E27.0 Other adrenocortical overactivity
0.708 0.292 0.000
E14.7 With multiple complications
0.703 0.297 0.000
E14.0 With coma
0.703 0.297 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.702 0.298 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.702 0.298 0.000
E16.4 Abnormal secretion of gastrin
0.702 0.298 0.000
E16.3 Increased secretion of glucagon
0.702 0.298 0.000
E11.0 With coma
0.701 0.299 0.000
E65-E68 Obesity and other hyperalimentation
0.689 0.311 0.000
E25 Adrenogenital disorders
0.688 0.312 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.686 0.313 0.000
E13.8 With unspecified complications
0.681 0.318 0.000
E13.7 With multiple complications
0.681 0.318 0.000
E13.6 With other specified complications
0.681 0.318 0.000
E13.5 With peripheral circulatory complications
0.681 0.318 0.000
E13.4 With neurological complications
0.681 0.318 0.000
E13.2 With renal complications
0.681 0.318 0.000
E13.1 With ketoacidosis
0.681 0.318 0.000
E13.0 With coma
0.681 0.318 0.000
K90.8 Other intestinal malabsorption
0.679 0.321 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.677 0.323 0.000
E03.1 Congenital hypothyroidism without goitre
0.676 0.324 0.000
E21.2 Other hyperparathyroidism
0.672 0.328 0.000
E14.2 Withrenal complications
0.672 0.328 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.670 0.330 0.000
E05.8 Other thyrotoxicosis
0.669 0.330 0.000
E03.8 Other specified hypothyroidism
0.667 0.333 0.000
L43.9 Lichen planus, unspecified
0.666 0.334 0.000
E28.3 Primary ovarian failure
0.656 0.344 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.652 0.348 0.000
E26 Hyperaldosteronism
0.649 0.351 0.000
L44 Other papulosquamous disorders
0.648 0.352 0.000
E14.6 With other specified complications
0.647 0.353 0.000
K90.3 Pancreatic steatorrhoea
0.646 0.353 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.646 0.353 0.000
K90.1 Tropical sprue
0.646 0.353 0.000
E20.9 Hypoparathyroidism, unspecified
0.645 0.355 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.643 0.356 0.000
E13.3 With ophthalmic complications
0.642 0.358 0.000
E27.8 Other specified disorders of adrenal gland
0.642 0.358 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.640 0.360 0.000
E24.8 Other Cushing's syndrome
0.636 0.364 0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.636 0.364 0.000
E24.3 Ectopic ACTH syndrome
0.636 0.364 0.000
E24.1 Nelson's syndrome
0.636 0.364 0.000
E22 Hyperfunction of pituitary gland
0.631 0.368 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.627 0.372 0.000
E23.1 Drug-induced hypopituitarism
0.627 0.372 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.002 0.379 0.619
G36 Other acute disseminated demyelination
0.010 0.382 0.608
E83.1 Disorders of iron metabolism
0.000 0.397 0.603
E06 Thyroiditis
0.597 0.403 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.002 0.406 0.592
L41 Parapsoriasis
0.594 0.406 0.000
E11.8 With unspecified complications
0.593 0.407 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.589 0.411 0.000
G37.5 Concentric sclerosis [Balo]
0.003 0.415 0.583
G37.4 Subacute necrotising myelitis
0.003 0.415 0.583
G37.2 Central pontine myelinolysis
0.003 0.415 0.583
G37.1 Central demyelination of corpus callosum
0.003 0.415 0.583
G37.0 Diffuse sclerosis
0.003 0.415 0.583
E29.1 Testicular hypofunction
0.583 0.417 0.000
N00-N08 Glomerular diseases
0.577 0.423 0.000
N04 Nephrotic syndrome
0.573 0.427 0.000
N05 Unspecified nephritic syndrome
0.572 0.428 0.000
L43.8 Other lichen planus
0.572 0.428 0.000
E31.0 Autoimmune polyglandular failure
0.571 0.428 0.000
E28.9 Ovarian dysfunction, unspecified
0.570 0.430 0.000
E28.8 Other ovarian dysfunction
0.570 0.430 0.000
E28.1 Androgen excess
0.570 0.430 0.000
E28.0 Oestrogen excess
0.570 0.430 0.000
E20.8 Other hypoparathyroidism
0.568 0.431 0.000
E20.1 Pseudohypoparathyroidism
0.568 0.431 0.000
E20.0 Idiopathic hypoparathyroidism
0.568 0.431 0.000
N04.9 Unspecified
0.563 0.437 0.000
E65 Localised adiposity
0.561 0.439 0.000
E28.2 Polycystic ovarian syndrome
0.560 0.440 0.000
D64.9 Anaemia, unspecified
0.553 0.447 0.000
E22.1 Hyperprolactinaemia
0.551 0.449 0.000
E07 Other disorders of thyroid
0.549 0.451 0.000
E50-E64 Other nutritional deficiencies
0.549 0.451 0.000
E34 Other endocrine disorders
0.544 0.456 0.000
E29.9 Testicular dysfunction, unspecified
0.543 0.457 0.000
E29.8 Other testicular dysfunction
0.543 0.457 0.000
E29.0 Testicular hyperfunction
0.543 0.457 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.543 0.457 0.000
E31.9 Polyglandular dysfunction, unspecified
0.538 0.462 0.000
E31.8 Other polyglandular dysfunction
0.538 0.462 0.000
E31.1 Polyglandular hyperfunction
0.538 0.462 0.000
E24.9 Cushing's syndrome, unspecified
0.530 0.470 0.000
L43.3 Subacute (active) lichen planus
0.530 0.470 0.000
L43.2 Lichenoid drug reaction
0.530 0.470 0.000
L43.1 Bullous lichen planus
0.530 0.470 0.000
L43.0 Hypertrophic lichen planus
0.530 0.470 0.000
N05.2 Diffuse membranous glomerulonephritis
0.529 0.471 0.000
L44.0 Pityriasis rubra pilaris
0.524 0.476 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.522 0.478 0.000
E46 Unspecified protein-energy malnutrition
0.521 0.479 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.517 0.483 0.000
E45 Retarded development following protein-energy malnutrition
0.517 0.483 0.000
E43 Unspecified severe protein-energy malnutrition
0.517 0.483 0.000
E42 Marasmic kwashiorkor
0.517 0.483 0.000
E41 Nutritional marasmus
0.517 0.483 0.000
E40 Kwashiorkor
0.517 0.483 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.514 0.486 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.514 0.486 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.514 0.486 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.514 0.486 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.514 0.486 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.514 0.486 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.514 0.486 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.514 0.486 0.000
E12.9 Without complications
0.514 0.486 0.000
E12.8 With unspecified complications
0.514 0.486 0.000
E12.7 With multiple complications
0.514 0.486 0.000
E12.6 With other specified complications
0.514 0.486 0.000
E12.5 With peripheral circulatory complications
0.514 0.486 0.000
E12.4 With neurological complications
0.514 0.486 0.000
E12.3 With ophthalmic complications
0.514 0.486 0.000
E12.2 With renal complications
0.514 0.486 0.000
E12.1 With ketoacidosis
0.514 0.486 0.000
E12.0 With coma
0.514 0.486 0.000
E30.9 Disorder of puberty, unspecified
0.514 0.486 0.000
E30.8 Other disorders of puberty
0.514 0.486 0.000
E30.1 Precocious puberty
0.514 0.486 0.000
E30.0 Delayed puberty
0.514 0.486 0.000
E32.9 Disease of thymus, unspecified
0.514 0.486 0.000
E32.8 Other diseases of thymus
0.514 0.486 0.000
E32.1 Abscess of thymus
0.514 0.486 0.000
E32.0 Persistent hyperplasia of thymus
0.514 0.486 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.514 0.486 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.514 0.486 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.514 0.486 0.000
L42 Pityriasis rosea
0.508 0.491 0.000
N04.2 Diffuse membranous glomerulonephritis
0.502 0.498 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.496 0.504 0.000
E67 Other hyperalimentation
0.494 0.506 0.000
E68 Sequelae of hyperalimentation
0.494 0.506 0.000
E25.9 Adrenogenital disorder, unspecified
0.493 0.506 0.000
E25.8 Other adrenogenital disorders
0.493 0.506 0.000
N05.1 Focal and segmental glomerular lesions
0.493 0.507 0.000
D64 Other anaemias
0.486 0.514 0.000
E21.0 Primary hyperparathyroidism
0.475 0.525 0.000
I10 Essential (primary) hypertension
0.470 0.530 0.000
N05.9 Unspecified
0.469 0.531 0.000
E26.8 Other hyperaldosteronism
0.465 0.534 0.000
E26.1 Secondary hyperaldosteronism
0.465 0.534 0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.465 0.534 0.000
L44.9 Papulosquamous disorder, unspecified
0.465 0.535 0.000
L44.8 Other specified papulosquamous disorders
0.465 0.535 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.465 0.535 0.000
L44.3 Lichen ruber moniliformis
0.465 0.535 0.000
L44.2 Lichen striatus
0.465 0.535 0.000
L44.1 Lichen nitidus
0.465 0.535 0.000
Q60-Q64 Congenital malformations of the urinary system
0.461 0.539 0.000
N03 Chronic nephritic syndrome
0.461 0.539 0.000
E26.9 Hyperaldosteronism, unspecified
0.455 0.544 0.000
N04.1 Focal and segmental glomerular lesions
0.454 0.546 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.453 0.547 0.000
E22.8 Other hyperfunction of pituitary gland
0.453 0.547 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.452 0.548 0.000
D60-D64 Aplastic and other anaemias
0.449 0.551 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.449 0.551 0.000
# Top node
0.449 0.551 0.000
N04.8 Other
0.449 0.551 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.449 0.551 0.000
Q61 Cystic kidney disease
0.448 0.552 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.445 0.555 0.000
I20-I25 Ischaemic heart diseases
0.445 0.555 0.000
G36.9 Acute disseminated demyelination, unspecified
0.007 0.557 0.436
G36.8 Other specified acute disseminated demyelination
0.007 0.557 0.436
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.007 0.557 0.436
G36.0 Neuromyelitis optica [Devic]
0.007 0.557 0.436
E53 Deficiency of other B group vitamins
0.441 0.559 0.000
I10-I15 Hypertensive diseases
0.440 0.560 0.000
E06.5 Other chronic thyroiditis
0.439 0.560 0.000
Q61.3 Polycystic kidney, unspecified
0.439 0.561 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.438 0.562 0.000
Chapter IX Diseases of the circulatory system
0.438 0.562 0.000
I24 Other acute ischaemic heart diseases
0.437 0.563 0.000
Q63 Other congenital malformations of kidney
0.436 0.564 0.000
I20 Angina pectoris
0.435 0.565 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.435 0.565 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.434 0.566 0.000
L41.1 Pityriasis lichenoides chronica
0.431 0.569 0.000
D80-D89 Certain disorders involving the immune mechanism
0.429 0.571 0.000
E06.4 Drug-induced thyroiditis
0.428 0.572 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.428 0.572 0.000
E06.0 Acute thyroiditis
0.428 0.572 0.000
N02 Recurrent and persistent haematuria
0.428 0.572 0.000
L41.9 Parapsoriasis, unspecified
0.426 0.574 0.000
L41.8 Other parapsoriasis
0.426 0.574 0.000
L41.5 Retiform parapsoriasis
0.426 0.574 0.000
L41.4 Large plaque parapsoriasis
0.426 0.574 0.000
L41.3 Small plaque parapsoriasis
0.426 0.574 0.000
L41.2 Lymphomatoid papulosis
0.426 0.574 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.426 0.574 0.000
I20.0 Unstable angina
0.424 0.576 0.000
Q60.0 Renal agenesis, unilateral
0.417 0.583 0.000
Y42.7 Androgens and anabolic congeners
0.416 0.584 0.000
E51 Thiamine deficiency
0.414 0.585 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.414 0.586 0.000
N06 Isolated proteinuria with specified morphological lesion
0.414 0.586 0.000
N01 Rapidly progressive nephritic syndrome
0.414 0.586 0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases
0.413 0.587 0.000
N03.1 Focal and segmental glomerular lesions
0.412 0.588 0.000
N04.7 Diffuse crescentic glomerulonephritis
0.411 0.589 0.000
N04.6 Dense deposit disease
0.411 0.589 0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis
0.411 0.589 0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis
0.411 0.589 0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis
0.411 0.589 0.000
E26.0 Primary hyperaldosteronism
0.411 0.589 0.000
N05.6 Dense deposit disease
0.410 0.590 0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis
0.410 0.590 0.000
N05.0 Minor glomerular abnormality
0.410 0.590 0.000
I20.9 Angina pectoris, unspecified
0.410 0.590 0.000
N05.8 Other
0.407 0.593 0.000
N02.2 Diffuse membranous glomerulonephritis
0.406 0.594 0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis
0.405 0.595 0.000
E07.8 Other specified disorders of thyroid
0.402 0.598 0.000
E06.1 Subacute thyroiditis
0.402 0.598 0.000
D80 Immunodeficiency with predominantly antibody defects
0.402 0.598 0.000
E53.8 Deficiency of other specified B group vitamins
0.401 0.599 0.000
E34.8 Other specified endocrine disorders
0.400 0.600 0.000
Q63.0 Accessory kidney
0.397 0.603 0.000
K90-K93 Other diseases of the digestive system
0.396 0.604 0.000
N00 Acute nephritic syndrome
0.396 0.604 0.000
E06.9 Thyroiditis, unspecified
0.395 0.605 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.394 0.606 0.000
E07.1 Dyshormogenetic goitre
0.394 0.606 0.000
E07.0 Hypersecretion of calcitonin
0.394 0.606 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.394 0.606 0.000
E63 Other nutritional deficiencies
0.394 0.606 0.000
E50 Vitamin A deficiency
0.394 0.606 0.000
E60 Dietary zinc deficiency
0.394 0.606 0.000
E59 Dietary selenium deficiency
0.394 0.606 0.000
E54 Ascorbic acid deficiency
0.394 0.606 0.000
E52 Niacin deficiency [pellagra]
0.394 0.606 0.000
E11.4 With neurological complications
0.391 0.608 0.000
N05.7 Diffuse crescentic glomerulonephritis
0.391 0.609 0.000
E34.5 Androgen resistance syndrome
0.390 0.609 0.000
E34.4 Constitutional tall stature
0.390 0.609 0.000
E34.3 Short stature, not elsewhere classified
0.390 0.609 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.390 0.609 0.000
E34.1 Other hypersecretion of intestinal hormones
0.390 0.609 0.000
Q61.2 Polycystic kidney, adult type
0.390 0.610 0.000
N08.8 Glomerular disorders in other diseases classified elsewhere
0.389 0.611 0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism
0.389 0.611 0.000
N08.1 Glomerular disorders in neoplastic diseases
0.389 0.611 0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere
0.389 0.611 0.000
Q43 Other congenital malformations of intestine
0.388 0.612 0.000
C83.3 Large cell (diffuse)
0.386 0.614 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.385 0.615 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.385 0.615 0.000
I24.8 Other forms of acute ischaemic heart disease
0.384 0.616 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.384 0.616 0.000
L10-L14 Bullous disorders
0.383 0.617 0.000
D55-D59 Haemolytic anaemias
0.380 0.620 0.000
E58 Dietary calcium deficiency
0.373 0.627 0.000
E06.3 Autoimmune thyroiditis
0.372 0.628 0.000
E44.1 Mild protein-energy malnutrition
0.371 0.629 0.000
E44.0 Moderate protein-energy malnutrition
0.371 0.629 0.000
I22 Subsequent myocardial infarction
0.370 0.630 0.000
K70-K77 Diseases of liver
0.369 0.631 0.000
E56 Other vitamin deficiencies
0.368 0.632 0.000
D64.3 Other sideroblastic anaemias
0.367 0.633 0.000
Chapter XI Diseases of the digestive system
0.365 0.635 0.000
N03.8 Other
0.364 0.636 0.000
I23 Certain current complications following acute myocardial infarction
0.363 0.637 0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis
0.363 0.637 0.000
E34.0 Carcinoid syndrome
0.360 0.639 0.000
D70 Agranulocytosis
0.360 0.640 0.000
D86 Sarcoidosis
0.360 0.640 0.000
Q61.9 Cystic kidney disease, unspecified
0.358 0.642 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.357 0.643 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.357 0.643 0.000
E67.8 Other specified hyperalimentation
0.354 0.646 0.000
E67.3 Hypervitaminosis D
0.354 0.646 0.000
E67.2 Megavitamin-B6 syndrome
0.354 0.646 0.000
E67.1 Hypercarotenaemia
0.354 0.646 0.000
E67.0 Hypervitaminosis A
0.354 0.646 0.000
D83 Common variable immunodeficiency
0.352 0.648 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.351 0.648 0.000
Q44.6 Cystic disease of liver
0.349 0.651 0.000
K70 Alcoholic liver disease
0.349 0.651 0.000
D64.4 Congenital dyserythropoietic anaemia
0.349 0.651 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.349 0.651 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.349 0.651 0.000
D64.0 Hereditary sideroblastic anaemia
0.349 0.651 0.000
E66 Obesity
0.348 0.652 0.000
Q63.2 Ectopic kidney
0.348 0.652 0.000
Q60.2 Renal agenesis, unspecified
0.343 0.657 0.000
Q63.8 Other specified congenital malformations of kidney
0.341 0.659 0.000
I00-I02 Acute rheumatic fever
0.340 0.660 0.000
K73 Chronic hepatitis, not elsewhere classified
0.339 0.661 0.000
K72 Hepatic failure, not elsewhere classified
0.337 0.663 0.000
N02.3 Diffuse mesangial proliferative glomerulonephritis
0.337 0.663 0.000
N04.0 Minor glomerular abnormality
0.334 0.665 0.000
Q43.9 Congenital malformation of intestine, unspecified
0.333 0.667 0.000
L13 Other bullous disorders
0.332 0.668 0.000
Chapter XIV Diseases of the genitourinary system
0.332 0.668 0.000
N03.7 Diffuse crescentic glomerulonephritis
0.331 0.669 0.000
N03.6 Dense deposit disease
0.331 0.669 0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis
0.331 0.669 0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis
0.331 0.669 0.000
N03.2 Diffuse membranous glomerulonephritis
0.331 0.669 0.000
N03.0 Minor glomerular abnormality
0.331 0.669 0.000
K75 Other inflammatory liver diseases
0.330 0.670 0.000
Q63.9 Congenital malformation of kidney, unspecified
0.329 0.671 0.000
K70.4 Alcoholic hepatic failure
0.328 0.672 0.000
D73 Diseases of spleen
0.326 0.674 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.325 0.675 0.000
Q00-Q07 Congenital malformations of the nervous system
0.323 0.677 0.000
Q61.8 Other cystic kidney diseases
0.321 0.679 0.000
Q61.1 Polycystic kidney, infantile type
0.321 0.679 0.000
K70.1 Alcoholic hepatitis
0.321 0.679 0.000
E51.2 Wernicke's encephalopathy
0.318 0.682 0.000
D86.3 Sarcoidosis of skin
0.318 0.682 0.000
D86.0 Sarcoidosis of lung
0.317 0.683 0.000
E53.1 Pyridoxine deficiency
0.316 0.683 0.000
E53.0 Riboflavin deficiency
0.316 0.683 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.315 0.685 0.000
Q60.6 Potter's syndrome
0.314 0.686 0.000
Q60.5 Renal hypoplasia, unspecified
0.314 0.686 0.000
Q60.4 Renal hypoplasia, bilateral
0.314 0.686 0.000
Q60.3 Renal hypoplasia, unilateral
0.314 0.686 0.000
Q60.1 Renal agenesis, bilateral
0.314 0.686 0.000
Q38.6 Other congenital malformations of mouth
0.313 0.686 0.000
Q63.3 Hyperplastic and giant kidney
0.312 0.687 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.312 0.688 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.312 0.688 0.000
I25 Chronic ischaemic heart disease
0.311 0.689 0.000
Q44.5 Other congenital malformations of bile ducts
0.311 0.689 0.000
I13 Hypertensive heart and renal disease
0.310 0.689 0.000
N17-N19 Renal failure
0.310 0.690 0.000
D59 Acquired haemolytic anaemia
0.310 0.690 0.000
N18 Chronic renal failure
0.310 0.690 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.308 0.692 0.000
E61 Deficiency of other nutrient elements
0.307 0.692 0.000
D81 Combined immunodeficiencies
0.307 0.693 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.307 0.693 0.000
N02.7 Diffuse crescentic glomerulonephritis
0.307 0.693 0.000
N02.6 Dense deposit disease
0.307 0.693 0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis
0.307 0.693 0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis
0.307 0.693 0.000
N02.1 Focal and segmental glomerular lesions
0.307 0.693 0.000
Q80-Q89 Other congenital malformations
0.306 0.694 0.000
K75.8 Other specified inflammatory liver diseases
0.304 0.696 0.000
D82 Immunodeficiency associated with other major defects
0.303 0.697 0.000
Q38.1 Ankyloglossia
0.302 0.697 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.302 0.698 0.000
N18.9 Chronic renal failure, unspecified
0.302 0.698 0.000
Q38.7 Pharyngeal pouch
0.302 0.698 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.300 0.700 0.000
K71 Toxic liver disease
0.300 0.700 0.000
K75.4 Autoimmune hepatitis
0.299 0.701 0.000
I20.1 Angina pectoris with documented spasm
0.299 0.701 0.000
K72.9 Hepatic failure, unspecified
0.297 0.703 0.000
Q44.7 Other congenital malformations of liver
0.297 0.703 0.000
E51.9 Thiamine deficiency, unspecified
0.297 0.703 0.000
E51.8 Other manifestations of thiamine deficiency
0.297 0.703 0.000
E51.1 Beriberi
0.297 0.703 0.000
Q43.8 Other specified congenital malformations of intestine
0.297 0.703 0.000
N01.9 Unspecified
0.297 0.703 0.000
N01.8 Other
0.297 0.703 0.000
N01.7 Diffuse crescentic glomerulonephritis
0.297 0.703 0.000
N01.6 Dense deposit disease
0.297 0.703 0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis
0.297 0.703 0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis
0.297 0.703 0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis
0.297 0.703 0.000
N01.2 Diffuse membranous glomerulonephritis
0.297 0.703 0.000
N01.1 Focal and segmental glomerular lesions
0.297 0.703 0.000
N01.0 Minor glomerular abnormality
0.297 0.703 0.000
N06.9 Unspecified
0.297 0.703 0.000
N06.8 Other
0.297 0.703 0.000
N06.7 Diffuse crescentic glomerulonephritis
0.297 0.703 0.000
N06.6 Dense deposit disease
0.297 0.703 0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis
0.297 0.703 0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis
0.297 0.703 0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis
0.297 0.703 0.000
N06.2 Diffuse membranous glomerulonephritis
0.297 0.703 0.000
N06.1 Focal and segmental glomerular lesions
0.297 0.703 0.000
N06.0 Minor glomerular abnormality
0.297 0.703 0.000
N07.9 Unspecified
0.297 0.703 0.000
N07.8 Other
0.297 0.703 0.000
N07.7 Diffuse crescentic glomerulonephritis
0.297 0.703 0.000
N07.6 Dense deposit disease
0.297 0.703 0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis
0.297 0.703 0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis
0.297 0.703 0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis
0.297 0.703 0.000
N07.2 Diffuse membranous glomerulonephritis
0.297 0.703 0.000
N07.1 Focal and segmental glomerular lesions
0.297 0.703 0.000
N07.0 Minor glomerular abnormality
0.297 0.703 0.000
Q45 Other congenital malformations of digestive system
0.297 0.703 0.000
D83.9 Common variable immunodeficiency, unspecified
0.297 0.703 0.000
N18.4 Chronic kidney disease, stage 4
0.297 0.703 0.000
L13.0 Dermatitis herpetiformis
0.296 0.704 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.296 0.704 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.296 0.704 0.000
D56 Thalassaemia
0.295 0.705 0.000
Q43.1 Hirschsprung's disease
0.294 0.706 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.294 0.706 0.000
D84 Other immunodeficiencies
0.293 0.707 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.293 0.707 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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